id category name description xref provided_by synonym iri object predicate relation same_as subject subsets GO:0099593 biolink:BiologicalProcess endocytosed synaptic vesicle to endosome fusion Fusion of an endocytosed synaptic vesicle with an endosome. go.json http://purl.obolibrary.org/obo/GO_0099593 GO:0099592 biolink:BiologicalProcess endocytosed synaptic vesicle processing via endosome The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles. go.json synaptic vesicle processing via endosome involved in synaptic vesicle recycling http://purl.obolibrary.org/obo/GO_0099592 GO:0099590 biolink:BiologicalProcess neurotransmitter receptor internalization A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor. go.json http://purl.obolibrary.org/obo/GO_0099590 GO:0002621 biolink:BiologicalProcess positive regulation of non-professional antigen presenting cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. go.json upregulation of non-professional antigen presenting cell antigen processing and presentation|up regulation of non-professional antigen presenting cell antigen processing and presentation|stimulation of non-professional antigen presenting cell antigen processing and presentation|up-regulation of non-professional antigen presenting cell antigen processing and presentation|activation of non-professional antigen presenting cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002621 GO:0099533 biolink:BiologicalProcess positive regulation of presynaptic cytosolic calcium concentration Any process that increases the concentration of calcium ions in the presynaptic cytosol. go.json http://purl.obolibrary.org/obo/GO_0099533 goslim_synapse GO:0051599 biolink:BiologicalProcess response to hydrostatic pressure Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it. go.json response to biomechanical stress|response to static fluid pressure http://purl.obolibrary.org/obo/GO_0051599 GO:0099534 biolink:MolecularActivity calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations. go.json regulation of presynaptic cytosolic calcium ion concentration by calcium ion buffering|presynaptic calcium ion buffering|calcium ion binding involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099534 goslim_synapse GO:0002622 biolink:BiologicalProcess regulation of B cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation. go.json regulation of B-lymphocyte antigen processing and presentation|regulation of B-cell antigen processing and presentation|regulation of B lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002622 GO:0051597 biolink:BiologicalProcess response to methylmercury Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus. go.json response to CH3-Hg+|response to MeHg+ http://purl.obolibrary.org/obo/GO_0051597 GO:0002623 biolink:BiologicalProcess negative regulation of B cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation. go.json down-regulation of B cell antigen processing and presentation|negative regulation of B-cell antigen processing and presentation|negative regulation of B lymphocyte antigen processing and presentation|negative regulation of B-lymphocyte antigen processing and presentation|downregulation of B cell antigen processing and presentation|down regulation of B cell antigen processing and presentation|inhibition of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002623 GO:0099531 biolink:BiologicalProcess presynaptic process involved in chemical synaptic transmission The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission. go.json http://purl.obolibrary.org/obo/GO_0099531 gocheck_do_not_annotate|goslim_synapse GO:0051598 biolink:BiologicalProcess meiotic recombination checkpoint signaling A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes. go.json pachytene checkpoint|meiotic recombination checkpoint|signal transduction involved in meiotic recombination checkpoint http://purl.obolibrary.org/obo/GO_0051598 GO:0099532 biolink:BiologicalProcess synaptic vesicle endosomal processing The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles. go.json synaptic vesicle processing via endosome http://purl.obolibrary.org/obo/GO_0099532 goslim_synapse GO:0002624 biolink:BiologicalProcess positive regulation of B cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation. go.json upregulation of B cell antigen processing and presentation|up regulation of B cell antigen processing and presentation|positive regulation of B-cell antigen processing and presentation|stimulation of B cell antigen processing and presentation|positive regulation of B lymphocyte antigen processing and presentation|up-regulation of B cell antigen processing and presentation|activation of B cell antigen processing and presentation|positive regulation of B-lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002624 GO:0099530 biolink:MolecularActivity G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane. go.json G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0099530 goslim_synapse GO:0002620 biolink:BiologicalProcess negative regulation of non-professional antigen presenting cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. go.json downregulation of non-professional antigen presenting cell antigen processing and presentation|down regulation of non-professional antigen presenting cell antigen processing and presentation|inhibition of non-professional antigen presenting cell antigen processing and presentation|down-regulation of non-professional antigen presenting cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002620 GO:0002629 biolink:BiologicalProcess negative regulation of proteolysis associated with antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. go.json down-regulation of proteolysis associated with antigen processing and presentation|down regulation of proteolysis associated with antigen processing and presentation|inhibition of proteolysis associated with antigen processing and presentation|downregulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002629 GO:0051591 biolink:BiologicalProcess response to cAMP Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus. go.json response to adenosine 3',5'-cyclophosphate|response to cyclic AMP|response to 3',5' cAMP|response to 3',5'-cAMP http://purl.obolibrary.org/obo/GO_0051591 GO:0051592 biolink:BiologicalProcess response to calcium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. go.json response to Ca2+ ion http://purl.obolibrary.org/obo/GO_0051592 GO:0099539 biolink:BiologicalProcess neuropeptide secretion from presynapse The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration. go.json neuropeptide secretion from presynapse via dense core granule exocytosis http://purl.obolibrary.org/obo/GO_0099539 goslim_synapse GO:0051590 biolink:BiologicalProcess positive regulation of neurotransmitter transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json up regulation of neurotransmitter transport|stimulation of neurotransmitter transport|up-regulation of neurotransmitter transport|activation of neurotransmitter transport|upregulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051590 GO:0002625 biolink:BiologicalProcess regulation of T cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation. go.json regulation of T-cell antigen processing and presentation|regulation of T lymphocyte antigen processing and presentation|regulation of T-lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002625 GO:0099537 biolink:BiologicalProcess trans-synaptic signaling Cell-cell signaling in either direction across the synaptic cleft. go.json http://purl.obolibrary.org/obo/GO_0099537 goslim_synapse GO:0051595 biolink:BiologicalProcess response to methylglyoxal Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. go.json response to pyruvaldehyde http://purl.obolibrary.org/obo/GO_0051595 GO:0051596 biolink:BiologicalProcess methylglyoxal catabolic process The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. MetaCyc:METHGLYUT-PWY|MetaCyc:Methylglyoxal-Detoxification go.json methylglyoxal breakdown|methylglyoxal catabolism|methylglyoxal degradation http://purl.obolibrary.org/obo/GO_0051596 GO:0099538 biolink:BiologicalProcess synaptic signaling via neuropeptide Cell-cell signaling to or from a synapse, mediated by a peptide. go.json http://purl.obolibrary.org/obo/GO_0099538 goslim_synapse GO:0002626 biolink:BiologicalProcess negative regulation of T cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation. go.json down regulation of T cell antigen processing and presentation|inhibition of T cell antigen processing and presentation|down-regulation of T cell antigen processing and presentation|negative regulation of T-cell antigen processing and presentation|negative regulation of T lymphocyte antigen processing and presentation|negative regulation of T-lymphocyte antigen processing and presentation|downregulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002626 GO:0051593 biolink:BiologicalProcess response to folic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus. go.json cellular response to folate|cellular response to vitamin B9 http://purl.obolibrary.org/obo/GO_0051593 GO:0002627 biolink:BiologicalProcess positive regulation of T cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation. go.json positive regulation of T-lymphocyte antigen processing and presentation|upregulation of T cell antigen processing and presentation|up regulation of T cell antigen processing and presentation|stimulation of T cell antigen processing and presentation|positive regulation of T-cell antigen processing and presentation|positive regulation of T lymphocyte antigen processing and presentation|activation of T cell antigen processing and presentation|up-regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002627 GO:0099535 biolink:CellularComponent synapse-associated extracellular matrix The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft. go.json extra-synaptic extracellular matrix http://purl.obolibrary.org/obo/GO_0099535 goslim_synapse GO:0099536 biolink:BiologicalProcess synaptic signaling Cell-cell signaling to, from or within a synapse. go.json http://purl.obolibrary.org/obo/GO_0099536 goslim_synapse GO:0002628 biolink:BiologicalProcess regulation of proteolysis associated with antigen processing and presentation Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002628 GO:0051594 biolink:BiologicalProcess detection of glucose The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal. go.json glucose sensing|glucose detection|glucose perception http://purl.obolibrary.org/obo/GO_0051594 GO:0099544 biolink:CellularComponent perisynaptic space The extracellular region immediately adjacent to to a synapse. go.json extrasynaptic space http://purl.obolibrary.org/obo/GO_0099544 goslim_synapse GO:0002632 biolink:BiologicalProcess negative regulation of granuloma formation Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation. go.json down-regulation of granuloma formation|down regulation of granuloma formation|inhibition of granuloma formation|downregulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002632 GO:0002633 biolink:BiologicalProcess positive regulation of granuloma formation Any process that activates or increases the frequency, rate, or extent of granuloma formation. go.json activation of granuloma formation|stimulation of granuloma formation|upregulation of granuloma formation|up-regulation of granuloma formation|up regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002633 GO:0099545 biolink:BiologicalProcess trans-synaptic signaling by trans-synaptic complex Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex. go.json http://purl.obolibrary.org/obo/GO_0099545 goslim_synapse GO:0002634 biolink:BiologicalProcess regulation of germinal center formation Any process that modulates the frequency, rate, or extent of germinal center formation. go.json http://purl.obolibrary.org/obo/GO_0002634 GO:0099542 biolink:BiologicalProcess trans-synaptic signaling by endocannabinoid Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand. go.json http://purl.obolibrary.org/obo/GO_0099542 goslim_synapse GO:0002635 biolink:BiologicalProcess negative regulation of germinal center formation Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. go.json down regulation of germinal center formation|inhibition of germinal center formation|downregulation of germinal center formation|down-regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0002635 GO:0099543 biolink:BiologicalProcess trans-synaptic signaling by soluble gas Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft. go.json http://purl.obolibrary.org/obo/GO_0099543 goslim_synapse GO:0099540 biolink:BiologicalProcess trans-synaptic signaling by neuropeptide Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft. go.json http://purl.obolibrary.org/obo/GO_0099540 goslim_synapse GO:0099541 biolink:BiologicalProcess trans-synaptic signaling by lipid Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid. go.json http://purl.obolibrary.org/obo/GO_0099541 goslim_synapse GO:0002630 biolink:BiologicalProcess positive regulation of proteolysis associated with antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. go.json up-regulation of proteolysis associated with antigen processing and presentation|up regulation of proteolysis associated with antigen processing and presentation|activation of proteolysis associated with antigen processing and presentation|stimulation of proteolysis associated with antigen processing and presentation|upregulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002630 GO:0002631 biolink:BiologicalProcess regulation of granuloma formation Any process that modulates the frequency, rate, or extent of granuloma formation. go.json http://purl.obolibrary.org/obo/GO_0002631 GO:0099548 biolink:BiologicalProcess trans-synaptic signaling by nitric oxide Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide. go.json http://purl.obolibrary.org/obo/GO_0099548 goslim_synapse GO:0002636 biolink:BiologicalProcess positive regulation of germinal center formation Any process that activates or increases the frequency, rate, or extent of germinal center formation. go.json up-regulation of germinal center formation|up regulation of germinal center formation|activation of germinal center formation|stimulation of germinal center formation|upregulation of germinal center formation http://purl.obolibrary.org/obo/GO_0002636 GO:0099549 biolink:BiologicalProcess trans-synaptic signaling by carbon monoxide Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide. go.json http://purl.obolibrary.org/obo/GO_0099549 goslim_synapse GO:0002637 biolink:BiologicalProcess regulation of immunoglobulin production Any process that modulates the frequency, rate, or extent of immunoglobulin production. go.json regulation of antibody production|regulation of immunoglobulin secretion|regulation of immunoglobulin biosynthetic process http://purl.obolibrary.org/obo/GO_0002637 GO:0002638 biolink:BiologicalProcess negative regulation of immunoglobulin production Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production. go.json negative regulation of immunoglobulin secretion|down-regulation of immunoglobulin production|down regulation of immunoglobulin production|inhibition of immunoglobulin production|downregulation of immunoglobulin production|negative regulation of immunoglobulin biosynthetic process http://purl.obolibrary.org/obo/GO_0002638 GO:0099546 biolink:BiologicalProcess protein catabolic process, modulating synaptic transmission Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission. go.json http://purl.obolibrary.org/obo/GO_0099546 goslim_synapse GO:0099547 biolink:BiologicalProcess regulation of translation at synapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the synapse. go.json http://purl.obolibrary.org/obo/GO_0099547 goslim_synapse GO:0002639 biolink:BiologicalProcess positive regulation of immunoglobulin production Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. go.json stimulation of immunoglobulin production|upregulation of immunoglobulin production|positive regulation of immunoglobulin secretion|positive regulation of immunoglobulin biosynthetic process|up-regulation of immunoglobulin production|up regulation of immunoglobulin production|activation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002639 GO:0099511 biolink:MolecularActivity voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel. go.json http://purl.obolibrary.org/obo/GO_0099511 goslim_synapse GO:0002600 biolink:BiologicalProcess positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. go.json up regulation of antigen processing and presentation of lipid antigen via MHC class Ib|activation of antigen processing and presentation of lipid antigen via MHC class Ib|positive regulation of lipid antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation of lipid antigen via MHC class Ib|upregulation of antigen processing and presentation of lipid antigen via MHC class Ib|up-regulation of antigen processing and presentation of lipid antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002600 GO:0099512 biolink:CellularComponent supramolecular fiber A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. go.json fibril http://purl.obolibrary.org/obo/GO_0099512 GO:0002601 biolink:BiologicalProcess regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. go.json regulation of polysaccharide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002601 GO:0099510 biolink:MolecularActivity calcium ion binding involved in regulation of cytosolic calcium ion concentration The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations. go.json regulation of cytosolic calcium ion concentration by calcium ion buffering http://purl.obolibrary.org/obo/GO_0099510 GO:0002602 biolink:BiologicalProcess negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. go.json down-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|negative regulation of polysaccharide antigen processing and presentation via MHC class II|downregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|down regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002602 GO:0099519 biolink:BiologicalProcess dense core granule cytoskeletal transport The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments. go.json dense core granule cytoskeletal transport|dense core vesicle cytoskeletal trafficking http://purl.obolibrary.org/obo/GO_0099519 GO:0002607 biolink:BiologicalProcess regulation of myeloid dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002607 GO:0002608 biolink:BiologicalProcess negative regulation of myeloid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. go.json downregulation of myeloid dendritic cell antigen processing and presentation|down regulation of myeloid dendritic cell antigen processing and presentation|inhibition of myeloid dendritic cell antigen processing and presentation|down-regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002608 GO:0002609 biolink:BiologicalProcess positive regulation of myeloid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. go.json up regulation of myeloid dendritic cell antigen processing and presentation|stimulation of myeloid dendritic cell antigen processing and presentation|up-regulation of myeloid dendritic cell antigen processing and presentation|activation of myeloid dendritic cell antigen processing and presentation|upregulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002609 GO:0099517 biolink:BiologicalProcess synaptic vesicle transport along microtubule The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors. go.json http://purl.obolibrary.org/obo/GO_0099517 goslim_synapse GO:0099518 biolink:BiologicalProcess vesicle cytoskeletal trafficking The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. go.json cytoskeletal fiber-based vesicle localization|vesicle cytoskeletal transport http://purl.obolibrary.org/obo/GO_0099518 GO:0002603 biolink:BiologicalProcess positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. go.json upregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|positive regulation of polysaccharide antigen processing and presentation via MHC class II|stimulation of antigen processing and presentation of polysaccharide antigen via MHC class II|up regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|up-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|activation of antigen processing and presentation of polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002603 GO:0099515 biolink:BiologicalProcess actin filament-based transport The transport of organelles or other particles from one location in the cell to another along actin filaments. go.json http://purl.obolibrary.org/obo/GO_0099515 GO:0099516 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0099516 GO:0002604 biolink:BiologicalProcess regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002604 GO:0002605 biolink:BiologicalProcess negative regulation of dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation. go.json down regulation of dendritic cell antigen processing and presentation|inhibition of dendritic cell antigen processing and presentation|down-regulation of dendritic cell antigen processing and presentation|downregulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002605 GO:0099513 biolink:CellularComponent polymeric cytoskeletal fiber A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. go.json http://purl.obolibrary.org/obo/GO_0099513 GO:0099514 biolink:BiologicalProcess synaptic vesicle cytoskeletal transport The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors. go.json http://purl.obolibrary.org/obo/GO_0099514 goslim_synapse GO:0002606 biolink:BiologicalProcess positive regulation of dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation. go.json upregulation of dendritic cell antigen processing and presentation|up regulation of dendritic cell antigen processing and presentation|stimulation of dendritic cell antigen processing and presentation|up-regulation of dendritic cell antigen processing and presentation|activation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002606 GO:0002610 biolink:BiologicalProcess regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002610 GO:0099522 biolink:CellularComponent region of cytosol Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol. go.json http://purl.obolibrary.org/obo/GO_0099522 GO:0002611 biolink:BiologicalProcess negative regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. go.json inhibition of plasmacytoid dendritic cell antigen processing and presentation|downregulation of plasmacytoid dendritic cell antigen processing and presentation|down-regulation of plasmacytoid dendritic cell antigen processing and presentation|down regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002611 GO:0099523 biolink:CellularComponent presynaptic cytosol The region of the cytosol consisting of all cytosol that is part of the presynapse. go.json http://purl.obolibrary.org/obo/GO_0099523 goslim_synapse GO:0099520 biolink:MolecularActivity ion antiporter activity involved in regulation of presynaptic membrane potential Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. go.json ion antiporter activity involved in regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099520 goslim_synapse GO:0002612 biolink:BiologicalProcess positive regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. go.json up-regulation of plasmacytoid dendritic cell antigen processing and presentation|up regulation of plasmacytoid dendritic cell antigen processing and presentation|activation of plasmacytoid dendritic cell antigen processing and presentation|stimulation of plasmacytoid dendritic cell antigen processing and presentation|upregulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002612 GO:0099521 biolink:MolecularActivity ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. go.json ATPase coupled ion transmembrane transporter activity involved in regulation of pre-synaptic membrane potential|ATPase-coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential http://purl.obolibrary.org/obo/GO_0099521 goslim_synapse GO:0002613 biolink:BiologicalProcess regulation of monocyte antigen processing and presentation Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002613 GO:0002618 biolink:BiologicalProcess positive regulation of macrophage antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation. go.json up regulation of macrophage antigen processing and presentation|stimulation of macrophage antigen processing and presentation|up-regulation of macrophage antigen processing and presentation|activation of macrophage antigen processing and presentation|upregulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002618 GO:0002619 biolink:BiologicalProcess regulation of non-professional antigen presenting cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002619 GO:0099528 biolink:MolecularActivity G protein-coupled neurotransmitter receptor activity Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go.json G-protein coupled neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0099528 GO:0099529 biolink:MolecularActivity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel). go.json http://purl.obolibrary.org/obo/GO_0099529 goslim_synapse GO:0099526 biolink:BiologicalProcess presynapse to nucleus signaling pathway A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications). go.json presynaptic signaling to nucleus http://purl.obolibrary.org/obo/GO_0099526 goslim_synapse GO:0002614 biolink:BiologicalProcess negative regulation of monocyte antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation. go.json downregulation of monocyte antigen processing and presentation|down regulation of monocyte antigen processing and presentation|inhibition of monocyte antigen processing and presentation|down-regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002614 GO:0002615 biolink:BiologicalProcess positive regulation of monocyte antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation. go.json stimulation of monocyte antigen processing and presentation|up regulation of monocyte antigen processing and presentation|up-regulation of monocyte antigen processing and presentation|activation of monocyte antigen processing and presentation|upregulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002615 GO:0099527 biolink:BiologicalProcess postsynapse to nucleus signaling pathway A series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications). go.json postsynaptic signaling to nucleus http://purl.obolibrary.org/obo/GO_0099527 goslim_synapse GO:0002616 biolink:BiologicalProcess regulation of macrophage antigen processing and presentation Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002616 GO:0099524 biolink:CellularComponent postsynaptic cytosol The region of the cytosol consisting of all cytosol that is part of the postsynapse. go.json http://purl.obolibrary.org/obo/GO_0099524 goslim_synapse GO:0002617 biolink:BiologicalProcess negative regulation of macrophage antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation. go.json downregulation of macrophage antigen processing and presentation|down regulation of macrophage antigen processing and presentation|inhibition of macrophage antigen processing and presentation|down-regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002617 GO:0099525 biolink:BiologicalProcess presynaptic dense core vesicle exocytosis The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels. go.json http://purl.obolibrary.org/obo/GO_0099525 goslim_synapse GO:0099577 biolink:BiologicalProcess regulation of translation at presynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. go.json http://purl.obolibrary.org/obo/GO_0099577 goslim_synapse GO:0099578 biolink:BiologicalProcess regulation of translation at postsynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. go.json http://purl.obolibrary.org/obo/GO_0099578 goslim_synapse GO:0099575 biolink:BiologicalProcess regulation of protein catabolic process at presynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. go.json http://purl.obolibrary.org/obo/GO_0099575 goslim_synapse GO:0099576 biolink:BiologicalProcess regulation of protein catabolic process at postsynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. go.json http://purl.obolibrary.org/obo/GO_0099576 goslim_synapse GO:0099573 biolink:CellularComponent glutamatergic postsynaptic density The post-synaptic specialization of a glutamatergic excitatory synapse. go.json postsynaptic specialization, glutamatergic neuron-to-neuron synapse http://purl.obolibrary.org/obo/GO_0099573 goslim_synapse GO:0099574 biolink:BiologicalProcess regulation of protein catabolic process at synapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating protein degradation at the synapse. go.json http://purl.obolibrary.org/obo/GO_0099574 goslim_synapse GO:0099571 biolink:CellularComponent postsynaptic cytoskeleton The portion of the cytoskeleton contained within the postsynapse. go.json http://purl.obolibrary.org/obo/GO_0099571 goslim_synapse GO:0099572 biolink:CellularComponent postsynaptic specialization A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. go.json http://purl.obolibrary.org/obo/GO_0099572 goslim_synapse GO:0099579 biolink:MolecularActivity G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential. go.json G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0099579 goslim_synapse GO:0099588 biolink:BiologicalProcess positive regulation of postsynaptic cytosolic calcium concentration Any process that increases the concentration of calcium ions in the postsynaptic cytosol. go.json http://purl.obolibrary.org/obo/GO_0099588 goslim_synapse GO:0099589 biolink:MolecularActivity serotonin receptor activity Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. go.json http://purl.obolibrary.org/obo/GO_0099589 GO:0099586 biolink:BiologicalProcess release of sequestered calcium ion into postsynaptic cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol. go.json http://purl.obolibrary.org/obo/GO_0099586 goslim_synapse GO:0099587 biolink:BiologicalProcess inorganic ion import across plasma membrane The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol. go.json inorganic ion import into cell http://purl.obolibrary.org/obo/GO_0099587 GO:0099585 biolink:BiologicalProcess release of sequestered calcium ion into presynaptic cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol. go.json http://purl.obolibrary.org/obo/GO_0099585 goslim_synapse GO:0099582 biolink:MolecularActivity neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol. go.json neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099582 goslim_synapse GO:0099583 biolink:MolecularActivity neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol. go.json neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099583 goslim_synapse GO:0099580 biolink:MolecularActivity ion antiporter activity involved in regulation of postsynaptic membrane potential Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. go.json ion antiporter activity involved in regulation of post-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099580 goslim_synapse GO:0099581 biolink:MolecularActivity ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. go.json ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099581 goslim_synapse GO:0099555 biolink:BiologicalProcess trans-synaptic signaling by nitric oxide, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099555 goslim_synapse GO:0099556 biolink:BiologicalProcess trans-synaptic signaling by carbon monoxide, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099556 goslim_synapse GO:0099553 biolink:BiologicalProcess trans-synaptic signaling by endocannabinoid, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099553 goslim_synapse GO:0099554 biolink:BiologicalProcess trans-synaptic signaling by soluble gas, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099554 goslim_synapse GO:0099551 biolink:BiologicalProcess trans-synaptic signaling by neuropeptide, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099551 goslim_synapse GO:0099552 biolink:BiologicalProcess trans-synaptic signaling by lipid, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099552 goslim_synapse GO:0099550 biolink:BiologicalProcess trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099550 goslim_synapse GO:0099559 biolink:BiologicalProcess maintenance of alignment of postsynaptic density and presynaptic active zone The process by which alignment between postsynaptic density and presynaptic active zone is maintained. go.json http://purl.obolibrary.org/obo/GO_0099559 goslim_synapse GO:0099557 biolink:BiologicalProcess trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099557 goslim_synapse GO:0099558 biolink:BiologicalProcess maintenance of synapse structure A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds. go.json synaptic maintenance http://purl.obolibrary.org/obo/GO_0099558 goslim_synapse GO:0099566 biolink:BiologicalProcess regulation of postsynaptic cytosolic calcium ion concentration Any process that regulates the concentration of calcium in the postsynaptic cytosol. go.json regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099566 goslim_synapse GO:0099567 biolink:MolecularActivity calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations. go.json regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering|postsynaptic calcium ion buffering|calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099567 goslim_synapse GO:0099564 biolink:BiologicalProcess modification of synaptic structure, modulating synaptic transmission Any process that modulates synaptic transmission via modification of the structure of the synapse. go.json http://purl.obolibrary.org/obo/GO_0099564 goslim_synapse GO:0099565 biolink:BiologicalProcess chemical synaptic transmission, postsynaptic The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. go.json postsynaptic process involved in chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0099565 goslim_synapse|gocheck_do_not_annotate GO:0099562 biolink:BiologicalProcess maintenance of postsynaptic density structure A process which maintains the organization and the arrangement of proteins in the presynaptic density. go.json http://purl.obolibrary.org/obo/GO_0099562 goslim_synapse GO:0099563 biolink:BiologicalProcess modification of synaptic structure Any process that modifies the structure/morphology of a synapse. go.json synapse remodelling http://purl.obolibrary.org/obo/GO_0099563 goslim_synapse GO:0099560 biolink:BiologicalProcess synaptic membrane adhesion The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane. go.json synapse adhesion between pre- and post-synapse http://purl.obolibrary.org/obo/GO_0099560 goslim_synapse GO:0099561 biolink:BiologicalProcess synaptic membrane adhesion to extracellular matrix The binding of a synaptic membrane to the extracellular matrix via adhesion molecules. go.json http://purl.obolibrary.org/obo/GO_0099561 goslim_synapse GO:0099568 biolink:CellularComponent cytoplasmic region Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. go.json http://purl.obolibrary.org/obo/GO_0099568 GO:0099569 biolink:CellularComponent presynaptic cytoskeleton The portion of the cytoskeleton contained within the presynapse. go.json http://purl.obolibrary.org/obo/GO_0099569 goslim_synapse GO:0002588 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. go.json stimulation of antigen processing and presentation of peptide antigen via MHC class II|positive regulation of peptide antigen processing and presentation via MHC class II|upregulation of antigen processing and presentation of peptide antigen via MHC class II|up-regulation of antigen processing and presentation of peptide antigen via MHC class II|up regulation of antigen processing and presentation of peptide antigen via MHC class II|activation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002588 GO:0051511 biolink:BiologicalProcess negative regulation of unidimensional cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. go.json down regulation of unidimensional cell growth|inhibition of unidimensional cell growth|down-regulation of unidimensional cell growth|downregulation of unidimensional cell growth|negative regulation of cell elongation http://purl.obolibrary.org/obo/GO_0051511 GO:0002589 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. go.json regulation of peptide antigen processing and presentation via MHC class I http://purl.obolibrary.org/obo/GO_0002589 GO:0051512 biolink:BiologicalProcess positive regulation of unidimensional cell growth Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. go.json upregulation of unidimensional cell growth|up regulation of unidimensional cell growth|positive regulation of cell elongation|stimulation of unidimensional cell growth|up-regulation of unidimensional cell growth|activation of unidimensional cell growth http://purl.obolibrary.org/obo/GO_0051512 GO:0051510 biolink:BiologicalProcess regulation of unidimensional cell growth Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. go.json regulation of cell elongation http://purl.obolibrary.org/obo/GO_0051510 GO:0002584 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen. go.json downregulation of antigen processing and presentation of peptide antigen|down regulation of antigen processing and presentation of peptide antigen|inhibition of antigen processing and presentation of peptide antigen|down-regulation of antigen processing and presentation of peptide antigen|negative regulation of peptide antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002584 GO:0051515 biolink:BiologicalProcess positive regulation of monopolar cell growth Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. go.json up regulation of monopolar cell growth|stimulation of monopolar cell growth|upregulation of monopolar cell growth|up-regulation of monopolar cell growth http://purl.obolibrary.org/obo/GO_0051515 GO:0002585 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen. go.json up-regulation of antigen processing and presentation of peptide antigen|activation of antigen processing and presentation of peptide antigen|upregulation of antigen processing and presentation of peptide antigen|positive regulation of peptide antigen processing and presentation|up regulation of antigen processing and presentation of peptide antigen|stimulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002585 GO:0051516 biolink:BiologicalProcess regulation of bipolar cell growth Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. go.json http://purl.obolibrary.org/obo/GO_0051516 GO:0002586 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. go.json regulation of peptide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002586 GO:0051513 biolink:BiologicalProcess regulation of monopolar cell growth Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. go.json http://purl.obolibrary.org/obo/GO_0051513 GO:0002587 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. go.json down-regulation of antigen processing and presentation of peptide antigen via MHC class II|down regulation of antigen processing and presentation of peptide antigen via MHC class II|inhibition of antigen processing and presentation of peptide antigen via MHC class II|downregulation of antigen processing and presentation of peptide antigen via MHC class II|negative regulation of peptide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002587 GO:0051514 biolink:BiologicalProcess negative regulation of monopolar cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. go.json down-regulation of monopolar cell growth|down regulation of monopolar cell growth|downregulation of monopolar cell growth|inhibition of monopolar cell growth http://purl.obolibrary.org/obo/GO_0051514 GO:0051519 biolink:BiologicalProcess activation of bipolar cell growth Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell. go.json http://purl.obolibrary.org/obo/GO_0051519 GO:0002580 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. go.json regulation of peptide or polysaccharide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002580 GO:0002581 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. go.json negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002581 GO:0051517 biolink:BiologicalProcess negative regulation of bipolar cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. go.json down regulation of bipolar cell growth|inhibition of bipolar cell growth|downregulation of bipolar cell growth|down-regulation of bipolar cell growth http://purl.obolibrary.org/obo/GO_0051517 GO:0002582 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. go.json up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002582 GO:0002583 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen. go.json regulation of peptide antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002583 GO:0051518 biolink:BiologicalProcess positive regulation of bipolar cell growth Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. go.json up-regulation of bipolar cell growth|up regulation of bipolar cell growth|stimulation of bipolar cell growth|upregulation of bipolar cell growth http://purl.obolibrary.org/obo/GO_0051518 GO:1905920 biolink:BiologicalProcess positive regulation of CoA-transferase activity Any process that activates or increases the frequency, rate or extent of CoA-transferase activity. go.json upregulation of CoA-transferase activity|up regulation of CoA-transferase activity|up-regulation of CoA-transferase activity|activation of CoA-transferase activity http://purl.obolibrary.org/obo/GO_1905920 GO:1905921 biolink:BiologicalProcess regulation of acetylcholine biosynthetic process Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process. go.json regulation of acetylcholine synthesis|regulation of acetylcholine formation|regulation of acetylcholine biosynthesis|regulation of acetylcholine anabolism http://purl.obolibrary.org/obo/GO_1905921 GO:1905922 biolink:BiologicalProcess negative regulation of acetylcholine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process. go.json inhibition of acetylcholine anabolism|down-regulation of acetylcholine formation|negative regulation of acetylcholine formation|downregulation of acetylcholine anabolism|down regulation of acetylcholine synthesis|down regulation of acetylcholine formation|inhibition of acetylcholine synthesis|downregulation of acetylcholine synthesis|downregulation of acetylcholine biosynthetic process|downregulation of acetylcholine biosynthesis|inhibition of acetylcholine formation|downregulation of acetylcholine formation|down-regulation of acetylcholine anabolism|negative regulation of acetylcholine anabolism|down regulation of acetylcholine biosynthesis|down regulation of acetylcholine biosynthetic process|inhibition of acetylcholine biosynthetic process|inhibition of acetylcholine biosynthesis|down regulation of acetylcholine anabolism|down-regulation of acetylcholine biosynthetic process|down-regulation of acetylcholine synthesis|negative regulation of acetylcholine synthesis|negative regulation of acetylcholine biosynthesis|down-regulation of acetylcholine biosynthesis http://purl.obolibrary.org/obo/GO_1905922 GO:1905923 biolink:BiologicalProcess positive regulation of acetylcholine biosynthetic process Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process. go.json up-regulation of acetylcholine anabolism|upregulation of acetylcholine formation|positive regulation of acetylcholine biosynthesis|up regulation of acetylcholine biosynthetic process|up regulation of acetylcholine anabolism|up regulation of acetylcholine biosynthesis|up-regulation of acetylcholine synthesis|activation of acetylcholine anabolism|positive regulation of acetylcholine anabolism|up-regulation of acetylcholine biosynthesis|up-regulation of acetylcholine biosynthetic process|activation of acetylcholine biosynthesis|activation of acetylcholine biosynthetic process|up-regulation of acetylcholine formation|up regulation of acetylcholine synthesis|activation of acetylcholine synthesis|positive regulation of acetylcholine synthesis|upregulation of acetylcholine anabolism|up regulation of acetylcholine formation|activation of acetylcholine formation|positive regulation of acetylcholine formation|upregulation of acetylcholine biosynthesis|upregulation of acetylcholine biosynthetic process|upregulation of acetylcholine synthesis http://purl.obolibrary.org/obo/GO_1905923 GO:1905924 biolink:BiologicalProcess obsolete regulation of invadopodium assembly OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium assembly. go.json regulation of invadopodium formation http://purl.obolibrary.org/obo/GO_1905924 GO:1905925 biolink:BiologicalProcess obsolete negative regulation of invadopodium assembly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium assembly. go.json down regulation of invadopodium assembly|downregulation of invadopodium formation|downregulation of invadopodium assembly|inhibition of invadopodium assembly|down regulation of invadopodium formation|inhibition of invadopodium formation|down-regulation of invadopodium formation|negative regulation of invadopodium formation|down-regulation of invadopodium assembly http://purl.obolibrary.org/obo/GO_1905925 GO:1905926 biolink:BiologicalProcess obsolete positive regulation of invadopodium assembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium assembly. go.json up regulation of invadopodium formation|up-regulation of invadopodium formation|activation of invadopodium formation|up-regulation of invadopodium assembly|up regulation of invadopodium assembly|upregulation of invadopodium formation|activation of invadopodium assembly|positive regulation of invadopodium formation|upregulation of invadopodium assembly http://purl.obolibrary.org/obo/GO_1905926 GO:1905927 biolink:BiologicalProcess obsolete regulation of invadopodium disassembly OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium disassembly. go.json http://purl.obolibrary.org/obo/GO_1905927 GO:1905928 biolink:BiologicalProcess obsolete negative regulation of invadopodium disassembly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium disassembly. go.json downregulation of invadopodium disassembly|down regulation of invadopodium disassembly|inhibition of invadopodium disassembly|down-regulation of invadopodium disassembly http://purl.obolibrary.org/obo/GO_1905928 GO:1905929 biolink:BiologicalProcess obsolete positive regulation of invadopodium disassembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium disassembly. go.json up-regulation of invadopodium disassembly|activation of invadopodium disassembly|upregulation of invadopodium disassembly|up regulation of invadopodium disassembly http://purl.obolibrary.org/obo/GO_1905929 GO:0002599 biolink:BiologicalProcess negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. go.json negative regulation of lipid antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation of lipid antigen via MHC class Ib|down regulation of antigen processing and presentation of lipid antigen via MHC class Ib|inhibition of antigen processing and presentation of lipid antigen via MHC class Ib|downregulation of antigen processing and presentation of lipid antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002599 GO:0051522 biolink:BiologicalProcess activation of monopolar cell growth Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell. go.json http://purl.obolibrary.org/obo/GO_0051522 GO:0051523 biolink:BiologicalProcess cell growth mode switching, monopolar to bipolar The process in which a cell switches from monopolar cell growth to bipolar cell growth. go.json new end take off|NETO http://purl.obolibrary.org/obo/GO_0051523 GO:0051520 biolink:BiologicalProcess termination of bipolar cell growth Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell. go.json http://purl.obolibrary.org/obo/GO_0051520 GO:0051521 biolink:BiologicalProcess termination of monopolar cell growth Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell. go.json http://purl.obolibrary.org/obo/GO_0051521 GO:0051526 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051526 GO:0002595 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. go.json regulation of peptide antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002595 GO:0002596 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. go.json negative regulation of peptide antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|down regulation of antigen processing and presentation of peptide antigen via MHC class Ib|inhibition of antigen processing and presentation of peptide antigen via MHC class Ib|downregulation of antigen processing and presentation of peptide antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002596 GO:0051527 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051527 GO:0002597 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. go.json up regulation of antigen processing and presentation of peptide antigen via MHC class Ib|activation of antigen processing and presentation of peptide antigen via MHC class Ib|positive regulation of peptide antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation of peptide antigen via MHC class Ib|upregulation of antigen processing and presentation of peptide antigen via MHC class Ib|up-regulation of antigen processing and presentation of peptide antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002597 GO:0051524 biolink:BiologicalProcess cell growth mode switching, bipolar to monopolar The process in which a cell switches from bipolar cell growth to monopolar cell growth. go.json http://purl.obolibrary.org/obo/GO_0051524 GO:0051525 biolink:MolecularActivity NFAT protein binding Interacting selectively and non-covalently with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system. go.json NFATx binding|NFAT5 protein binding|nuclear factor of activated T cell protein binding|NFATc4 binding|NFAT4 protein binding|NFAT3 protein binding|NFATc3 binding|NFAT2 protein binding|NFATc2 binding|NFAT1 protein binding|NFATc1 binding|NFATc binding|NFATp binding|NFAT binding|non-calcium-regulated NFAT protein binding http://purl.obolibrary.org/obo/GO_0051525 GO:0002598 biolink:BiologicalProcess regulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. go.json regulation of lipid antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002598 GO:0002591 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. go.json stimulation of antigen processing and presentation of peptide antigen via MHC class I|up regulation of antigen processing and presentation of peptide antigen via MHC class I|activation of antigen processing and presentation of peptide antigen via MHC class I|up-regulation of antigen processing and presentation of peptide antigen via MHC class I|upregulation of antigen processing and presentation of peptide antigen via MHC class I|positive regulation of peptide antigen processing and presentation via MHC class I http://purl.obolibrary.org/obo/GO_0002591 GO:0002592 biolink:BiologicalProcess regulation of antigen processing and presentation via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. go.json http://purl.obolibrary.org/obo/GO_0002592 GO:0002593 biolink:BiologicalProcess negative regulation of antigen processing and presentation via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. go.json down-regulation of antigen processing and presentation via MHC class Ib|downregulation of antigen processing and presentation via MHC class Ib|down regulation of antigen processing and presentation via MHC class Ib|inhibition of antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002593 GO:0051528 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051528 GO:0002594 biolink:BiologicalProcess positive regulation of antigen processing and presentation via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. go.json upregulation of antigen processing and presentation via MHC class Ib|up regulation of antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation via MHC class Ib|up-regulation of antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002594 GO:0051529 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051529 GO:0002590 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. go.json negative regulation of peptide antigen processing and presentation via MHC class I|downregulation of antigen processing and presentation of peptide antigen via MHC class I|down regulation of antigen processing and presentation of peptide antigen via MHC class I|inhibition of antigen processing and presentation of peptide antigen via MHC class I|down-regulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002590 GO:1905930 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. go.json regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of VSMC differentiation involved in phenotypic dimorphism|regulation of VSMC differentiation involved in phenotypic switching http://purl.obolibrary.org/obo/GO_1905930 GO:1905931 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. go.json downregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of VSMC differentiation involved in phenotypic switching|down regulation of VSMC differentiation involved in phenotypic dimorphism|downregulation of VSMC differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of VSMC differentiation involved in phenotypic dimorphism|down-regulation of VSMC differentiation involved in phenotypic dimorphism|down regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of VSMC differentiation involved in phenotypic dimorphism|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of VSMC differentiation involved in phenotypic switching|down-regulation of VSMC differentiation involved in phenotypic switching|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of VSMC differentiation involved in phenotypic dimorphism|down regulation of VSMC differentiation involved in phenotypic switching|downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism http://purl.obolibrary.org/obo/GO_1905931 GO:1905932 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. go.json activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of VSMC differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of VSMC differentiation involved in phenotypic dimorphism|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|upregulation of VSMC differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of VSMC differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic switching|upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of VSMC differentiation involved in phenotypic switching|upregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic dimorphism|activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of VSMC differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|upregulation of VSMC differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of VSMC differentiation involved in phenotypic dimorphism|up regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism http://purl.obolibrary.org/obo/GO_1905932 GO:1905933 biolink:BiologicalProcess regulation of cell fate determination Any process that modulates the frequency, rate or extent of cell fate determination. go.json http://purl.obolibrary.org/obo/GO_1905933 GO:1905934 biolink:BiologicalProcess negative regulation of cell fate determination Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination. go.json down regulation of cell fate determination|inhibition of cell fate determination|downregulation of cell fate determination|down-regulation of cell fate determination http://purl.obolibrary.org/obo/GO_1905934 GO:1905935 biolink:BiologicalProcess positive regulation of cell fate determination Any process that activates or increases the frequency, rate or extent of cell fate determination. go.json up-regulation of cell fate determination|up regulation of cell fate determination|activation of cell fate determination|upregulation of cell fate determination http://purl.obolibrary.org/obo/GO_1905935 GO:1905936 biolink:BiologicalProcess regulation of germ cell proliferation Any process that modulates the frequency, rate or extent of germ cell proliferation. go.json http://purl.obolibrary.org/obo/GO_1905936 GO:1905937 biolink:BiologicalProcess negative regulation of germ cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. go.json down-regulation of germ cell proliferation|down regulation of germ cell proliferation|inhibition of germ cell proliferation|downregulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905937 GO:1905938 biolink:BiologicalProcess positive regulation of germ cell proliferation Any process that activates or increases the frequency, rate or extent of germ cell proliferation. go.json up regulation of germ cell proliferation|activation of germ cell proliferation|upregulation of germ cell proliferation|up-regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905938 GO:1905939 biolink:BiologicalProcess regulation of gonad development Any process that modulates the frequency, rate or extent of gonad development. go.json regulation of gonadogenesis http://purl.obolibrary.org/obo/GO_1905939 GO:0051533 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051533 GO:0002566 biolink:BiologicalProcess somatic diversification of immune receptors via somatic mutation The process in which immune receptor genes are diversified through somatic mutation. go.json http://purl.obolibrary.org/obo/GO_0002566 GO:0075501 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075501 GO:0051534 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051534 GO:0002567 biolink:BiologicalProcess somatic diversification of FREP-based immune receptors The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails. go.json http://purl.obolibrary.org/obo/GO_0002567 GO:0075502 biolink:BiologicalProcess endosome membrane permeabilization involved in viral entry into host cell Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm. go.json viral entry into host cell via caveolae-mediated endocytosis followed by endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by endosome membrane permeabilization http://purl.obolibrary.org/obo/GO_0075502 GO:0002568 biolink:BiologicalProcess somatic diversification of T cell receptor genes The somatic process that results in the generation of sequence diversity of T cell receptor genes. go.json somatic diversification of TCR genes http://purl.obolibrary.org/obo/GO_0002568 GO:0051531 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051531 GO:0051532 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051532 GO:0075503 biolink:BiologicalProcess fusion of virus membrane with host macropinosome membrane Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm. go.json viral entry into host cell via macropinocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via macropinocytosis followed by membrane fusion with the host macropinosome membrane http://purl.obolibrary.org/obo/GO_0075503 GO:0002569 biolink:BiologicalProcess somatic diversification of immune receptors by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene. go.json http://purl.obolibrary.org/obo/GO_0002569 GO:0002562 biolink:BiologicalProcess somatic diversification of immune receptors via germline recombination within a single locus The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. go.json http://purl.obolibrary.org/obo/GO_0002562 GO:0051537 biolink:MolecularActivity 2 iron, 2 sulfur cluster binding Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. go.json 2 iron, 2 sulphur cluster binding|diiron disulfide cluster binding|2 Fe 2 S cluster binding|diiron disulphide cluster binding|iron-sulphur cluster 2Fe-2S binding|2Fe-2S cluster binding|iron-sulfur cluster 2Fe-2S binding http://purl.obolibrary.org/obo/GO_0051537 GO:0075504 biolink:BiologicalProcess macropinosomal membrane permeabilization involved in viral entry into host cell Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm. go.json viral entry into host cell via macropinocytosis followed by macropinosomal membrane permeabilization http://purl.obolibrary.org/obo/GO_0075504 GO:0051538 biolink:MolecularActivity 3 iron, 4 sulfur cluster binding Interacting selectively and non-covalently with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing. go.json triiron tetrasulfide cluster binding|iron-sulfur cluster 3Fe-4S binding|3 Fe 4 S cluster binding|triiron tetrasulphide cluster binding|iron-sulphur cluster 3Fe-4S binding|3Fe-4S cluster binding|3 iron, 4 sulphur cluster binding http://purl.obolibrary.org/obo/GO_0051538 GO:0002563 biolink:BiologicalProcess somatic diversification of immune receptors via alternate splicing The process in which immune receptor genes are diversified through alternate splicing. go.json http://purl.obolibrary.org/obo/GO_0002563 GO:0075505 biolink:BiologicalProcess entry of intact viral capsid into host nucleus through nuclear pore complex Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC). go.json http://purl.obolibrary.org/obo/GO_0075505 GO:0051535 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051535 GO:0075506 biolink:BiologicalProcess entry of viral genome into host nucleus through nuclear pore complex via importin Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery. go.json entry of viral genome into host nucleus via cellular importin transport through the nuclear pore complex http://purl.obolibrary.org/obo/GO_0075506 GO:0002564 biolink:BiologicalProcess alternate splicing of immunoglobulin genes The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons. go.json alternate splicing of antibody genes http://purl.obolibrary.org/obo/GO_0002564 GO:0051536 biolink:MolecularActivity iron-sulfur cluster binding Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms. go.json iron sulphur cluster binding|iron sulfur cluster binding|iron-sulphur cluster binding|Fe/S binding http://purl.obolibrary.org/obo/GO_0051536 goslim_metagenomics GO:0002565 biolink:BiologicalProcess somatic diversification of immune receptors via gene conversion The process in which immune receptor genes are diversified through gene conversion. go.json http://purl.obolibrary.org/obo/GO_0002565 GO:0075507 biolink:BiologicalProcess entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm. go.json http://purl.obolibrary.org/obo/GO_0075507 GO:0075508 biolink:BiologicalProcess entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm. go.json entry of viral genome into host nucleus via attachment of capsid to nuclear pore complex and release of genome into nucleoplasm http://purl.obolibrary.org/obo/GO_0075508 GO:0075509 biolink:BiologicalProcess endocytosis involved in viral entry into host cell Any endocytosis that is involved in the uptake of a virus into a host cell. VZ:977 go.json virus endocytosis by host|viral penetration via endocytosis followed by endosome disruption|viral entry into host cell via endocytosis http://purl.obolibrary.org/obo/GO_0075509 GO:0051539 biolink:MolecularActivity 4 iron, 4 sulfur cluster binding Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. go.json 4Fe-4S cluster binding|iron-sulfur cluster 4Fe-4S binding|tetrairon tetrasulphide cluster binding|tetrairon tetrasulfide cluster binding|4 Fe 4 S cluster binding|iron-sulphur cluster 4Fe-4S binding|4 iron, 4 sulphur cluster binding http://purl.obolibrary.org/obo/GO_0051539 GO:0002560 biolink:BiologicalProcess basophil mediated immunity Any process involved in the carrying out of an immune response by a basophil. go.json http://purl.obolibrary.org/obo/GO_0002560 GO:0002561 biolink:BiologicalProcess basophil degranulation The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil. go.json http://purl.obolibrary.org/obo/GO_0002561 GO:1905940 biolink:BiologicalProcess negative regulation of gonad development Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. go.json down-regulation of gonad development|down-regulation of gonadogenesis|negative regulation of gonadogenesis|down regulation of gonad development|down regulation of gonadogenesis|downregulation of gonad development|inhibition of gonad development|inhibition of gonadogenesis|downregulation of gonadogenesis http://purl.obolibrary.org/obo/GO_1905940 GO:1905941 biolink:BiologicalProcess positive regulation of gonad development Any process that activates or increases the frequency, rate or extent of gonad development. go.json up regulation of gonadogenesis|activation of gonadogenesis|positive regulation of gonadogenesis|upregulation of gonad development|upregulation of gonadogenesis|up-regulation of gonad development|up-regulation of gonadogenesis|up regulation of gonad development|activation of gonad development http://purl.obolibrary.org/obo/GO_1905941 GO:1905942 biolink:BiologicalProcess regulation of formation of growth cone in injured axon Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon. go.json http://purl.obolibrary.org/obo/GO_1905942 GO:1905943 biolink:BiologicalProcess negative regulation of formation of growth cone in injured axon Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon. go.json downregulation of formation of growth cone in injured axon|down regulation of formation of growth cone in injured axon|inhibition of formation of growth cone in injured axon|down-regulation of formation of growth cone in injured axon http://purl.obolibrary.org/obo/GO_1905943 GO:1905944 biolink:BiologicalProcess positive regulation of formation of growth cone in injured axon Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon. go.json up regulation of formation of growth cone in injured axon|up-regulation of formation of growth cone in injured axon|activation of formation of growth cone in injured axon|upregulation of formation of growth cone in injured axon http://purl.obolibrary.org/obo/GO_1905944 GO:1905945 biolink:BiologicalProcess regulation of response to calcium ion Any process that modulates the frequency, rate or extent of response to calcium ion. go.json regulation of response to Ca2+ ion http://purl.obolibrary.org/obo/GO_1905945 GO:1905946 biolink:BiologicalProcess negative regulation of response to calcium ion Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion. go.json downregulation of response to Ca2+ ion|downregulation of response to calcium ion|inhibition of response to calcium ion|down regulation of response to Ca2+ ion|inhibition of response to Ca2+ ion|negative regulation of response to Ca2+ ion|down-regulation of response to Ca2+ ion|down-regulation of response to calcium ion|down regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_1905946 GO:1905947 biolink:BiologicalProcess positive regulation of response to calcium ion Any process that activates or increases the frequency, rate or extent of response to calcium ion. go.json up regulation of response to Ca2+ ion|activation of response to Ca2+ ion|up-regulation of response to Ca2+ ion|up-regulation of response to calcium ion|up regulation of response to calcium ion|activation of response to calcium ion|upregulation of response to Ca2+ ion|upregulation of response to calcium ion|positive regulation of response to Ca2+ ion http://purl.obolibrary.org/obo/GO_1905947 GO:1905948 biolink:MolecularActivity ABC-type 3',5'-cyclic GMP transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out). go.json 3',5'-cyclic GMP transmembrane-transporting ATPase activity|ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity|ATPase-coupled cGMP transmembrane transporter activity|ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1905948 GO:1905949 biolink:BiologicalProcess negative regulation of calcium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane. go.json downregulation of calcium ion import across plasma membrane|inhibition of calcium ion import across plasma membrane|down-regulation of calcium ion import across plasma membrane|down regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1905949 GO:0051530 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051530 GO:0051544 biolink:BiologicalProcess positive regulation of elastin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. go.json up regulation of elastin biosynthetic process|stimulation of elastin biosynthetic process|up-regulation of elastin biosynthetic process|activation of elastin biosynthetic process|upregulation of elastin biosynthetic process http://purl.obolibrary.org/obo/GO_0051544 GO:0002577 biolink:BiologicalProcess regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation. go.json http://purl.obolibrary.org/obo/GO_0002577 GO:0002578 biolink:BiologicalProcess negative regulation of antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation. go.json down-regulation of antigen processing and presentation|down regulation of antigen processing and presentation|inhibition of antigen processing and presentation|downregulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002578 GO:0051545 biolink:BiologicalProcess negative regulation of elastin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. go.json downregulation of elastin biosynthetic process|down regulation of elastin biosynthetic process|inhibition of elastin biosynthetic process|down-regulation of elastin biosynthetic process http://purl.obolibrary.org/obo/GO_0051545 GO:0002579 biolink:BiologicalProcess positive regulation of antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. go.json stimulation of antigen processing and presentation|upregulation of antigen processing and presentation|up-regulation of antigen processing and presentation|up regulation of antigen processing and presentation|activation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002579 GO:0051542 biolink:BiologicalProcess elastin biosynthetic process The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries. go.json http://purl.obolibrary.org/obo/GO_0051542 GO:0051543 biolink:BiologicalProcess regulation of elastin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. go.json http://purl.obolibrary.org/obo/GO_0051543 GO:0051548 biolink:BiologicalProcess negative regulation of keratinocyte migration Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration. go.json down regulation of keratinocyte migration|inhibition of keratinocyte migration|down-regulation of keratinocyte migration|downregulation of keratinocyte migration http://purl.obolibrary.org/obo/GO_0051548 GO:0002573 biolink:BiologicalProcess myeloid leukocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. go.json myeloid leucocyte differentiation http://purl.obolibrary.org/obo/GO_0002573 GO:0051549 biolink:BiologicalProcess positive regulation of keratinocyte migration Any process that activates or increases the frequency, rate or extent of keratinocyte migration. go.json upregulation of keratinocyte migration|stimulation of keratinocyte migration|up regulation of keratinocyte migration|activation of keratinocyte migration|up-regulation of keratinocyte migration http://purl.obolibrary.org/obo/GO_0051549 GO:0002574 biolink:BiologicalProcess thrombocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. go.json http://purl.obolibrary.org/obo/GO_0002574 GO:0002575 biolink:BiologicalProcess basophil chemotaxis The movement of a basophil in response to an external stimulus. go.json http://purl.obolibrary.org/obo/GO_0002575 GO:0051546 biolink:BiologicalProcess keratinocyte migration The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another. go.json http://purl.obolibrary.org/obo/GO_0051546 GO:0051547 biolink:BiologicalProcess regulation of keratinocyte migration Any process that modulates the frequency, rate or extent of keratinocyte migration. go.json http://purl.obolibrary.org/obo/GO_0051547 GO:0002576 biolink:BiologicalProcess platelet degranulation The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. go.json platelet exocytosis http://purl.obolibrary.org/obo/GO_0002576 GO:0002570 biolink:BiologicalProcess somatic diversification of immunoglobulin genes by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions. go.json somatic diversification of antibody genes by N region addition http://purl.obolibrary.org/obo/GO_0002570 GO:0002571 biolink:BiologicalProcess somatic diversification of T cell receptor genes by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene. go.json somatic diversification of TCR genes by N region addition http://purl.obolibrary.org/obo/GO_0002571 GO:0002572 biolink:BiologicalProcess pro-T cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed. go.json pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002572 GO:1905960 biolink:BiologicalProcess response to differentiation-inducing factor 2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus. go.json response to DIF2|response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one|response to DIF-2 http://purl.obolibrary.org/obo/GO_1905960 GO:1905950 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_1905950 GO:1905951 biolink:BiologicalProcess mitochondrion DNA recombination Any DNA recombination that takes place in mitochondrion. go.json DNA recombination in mitochondria http://purl.obolibrary.org/obo/GO_1905951 GO:1905952 biolink:BiologicalProcess regulation of lipid localization Any process that modulates the frequency, rate or extent of lipid localization. go.json regulation of lipid localisation http://purl.obolibrary.org/obo/GO_1905952 GO:1905953 biolink:BiologicalProcess negative regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. go.json down-regulation of lipid localization|downregulation of lipid localisation|down regulation of lipid localisation|inhibition of lipid localisation|downregulation of lipid localization|negative regulation of lipid localisation|down-regulation of lipid localisation|down regulation of lipid localization|inhibition of lipid localization http://purl.obolibrary.org/obo/GO_1905953 GO:1905954 biolink:BiologicalProcess positive regulation of lipid localization Any process that activates or increases the frequency, rate or extent of lipid localization. go.json upregulation of lipid localization|up-regulation of lipid localisation|activation of lipid localisation|up regulation of lipid localization|up-regulation of lipid localization|upregulation of lipid localisation|activation of lipid localization|positive regulation of lipid localisation|up regulation of lipid localisation http://purl.obolibrary.org/obo/GO_1905954 GO:1905955 biolink:BiologicalProcess negative regulation of endothelial tube morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. go.json downregulation of endothelial tube morphogenesis|down regulation of endothelial tube morphogenesis|inhibition of endothelial tube morphogenesis|down-regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905955 GO:1905956 biolink:BiologicalProcess positive regulation of endothelial tube morphogenesis Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. go.json up regulation of endothelial tube morphogenesis|up-regulation of endothelial tube morphogenesis|activation of endothelial tube morphogenesis|upregulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905956 GO:1905957 biolink:BiologicalProcess regulation of cellular response to alcohol Any process that modulates the frequency, rate or extent of cellular response to alcohol. go.json http://purl.obolibrary.org/obo/GO_1905957 GO:1905958 biolink:BiologicalProcess negative regulation of cellular response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol. go.json downregulation of cellular response to alcohol|down regulation of cellular response to alcohol|inhibition of cellular response to alcohol|down-regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905958 GO:1905959 biolink:BiologicalProcess positive regulation of cellular response to alcohol Any process that activates or increases the frequency, rate or extent of cellular response to alcohol. go.json up regulation of cellular response to alcohol|up-regulation of cellular response to alcohol|activation of cellular response to alcohol|upregulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905959 GO:0051540 biolink:MolecularActivity metal cluster binding Interacting selectively and non-covalently with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters. go.json http://purl.obolibrary.org/obo/GO_0051540 goslim_pir GO:0051541 biolink:BiologicalProcess elastin metabolic process The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue. go.json elastin metabolism http://purl.obolibrary.org/obo/GO_0051541 GO:0051555 biolink:BiologicalProcess flavonol biosynthetic process The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities. MetaCyc:PWY-3101 go.json http://purl.obolibrary.org/obo/GO_0051555 GO:0075522 biolink:BiologicalProcess IRES-dependent viral translational initiation Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation. VZ:867 go.json http://purl.obolibrary.org/obo/GO_0075522 GO:0002544 biolink:BiologicalProcess chronic inflammatory response Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response. go.json http://purl.obolibrary.org/obo/GO_0002544 GO:0075523 biolink:BiologicalProcess viral translational frameshifting A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins. VZ:860 go.json ribosomal frameshifting involved in viral translation http://purl.obolibrary.org/obo/GO_0075523 GO:0002545 biolink:BiologicalProcess chronic inflammatory response to non-antigenic stimulus A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma. go.json http://purl.obolibrary.org/obo/GO_0002545 GO:0051556 biolink:BiologicalProcess leucoanthocyanidin metabolic process The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids. MetaCyc:PWY1F-823 go.json leucoanthocyanidin metabolism http://purl.obolibrary.org/obo/GO_0051556 GO:0002546 biolink:BiologicalProcess negative regulation of tissue kallikrein-kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade. go.json down regulation of tissue kallikrein-kinin cascade|inhibition of tissue kallikrein-kinin cascade|downregulation of tissue kallikrein-kinin cascade|negative regulation of glandular kallikrein-kinin cascade|down-regulation of tissue kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002546 GO:0075524 biolink:BiologicalProcess ribosomal skipping A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue. VZ:914 go.json http://purl.obolibrary.org/obo/GO_0075524 GO:0051553 biolink:BiologicalProcess flavone biosynthetic process The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone). go.json 2-phenylchromone biosynthesis|2-phenylchromone biosynthetic process|2-phenyl-4H-1-benzopyran-4-one biosynthesis|2-phenyl-4H-1-benzopyran-4-one biosynthetic process http://purl.obolibrary.org/obo/GO_0051553 GO:0075525 biolink:BiologicalProcess viral translational termination-reinitiation A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF. VZ:858 go.json viral translation involving translational stop-start|termination reinitiation involved in viral translation|viral translation involving termination-reinitiation|viral translation involving termination re-initiation http://purl.obolibrary.org/obo/GO_0075525 GO:0051554 biolink:BiologicalProcess flavonol metabolic process The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities. go.json flavonol metabolism http://purl.obolibrary.org/obo/GO_0051554 GO:0002547 biolink:BiologicalProcess positive regulation of tissue kallikrein-kinin cascade Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade. go.json up-regulation of tissue kallikrein-kinin cascade|up regulation of tissue kallikrein-kinin cascade|activation of tissue kallikrein-kinin cascade|positive regulation of glandular kallikrein-kinin cascade|stimulation of tissue kallikrein-kinin cascade|upregulation of tissue kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002547 GO:0002540 biolink:BiologicalProcess leukotriene production involved in inflammatory response The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go.json leukotriene production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002540 GO:0075526 biolink:BiologicalProcess cap snatching A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs. VZ:839 go.json cap snatching involved in viral mRNA transcription http://purl.obolibrary.org/obo/GO_0075526 GO:0051559 biolink:BiologicalProcess phlobaphene biosynthetic process The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols. go.json http://purl.obolibrary.org/obo/GO_0051559 GO:0075527 biolink:BiologicalProcess viral RNA editing The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon. VZ:857 go.json RNA editing involved in viral mRNA transcription http://purl.obolibrary.org/obo/GO_0075527 GO:0002541 biolink:BiologicalProcess activation of plasma proteins involved in acute inflammatory response Any process activating plasma proteins by proteolysis as part of an acute inflammatory response. go.json http://purl.obolibrary.org/obo/GO_0002541 GO:0075528 biolink:BiologicalProcess modulation by virus of host immune response The process in which a virus effects a change in the host immune response. go.json regulation by virus of host immune system process http://purl.obolibrary.org/obo/GO_0075528 GO:0051557 biolink:BiologicalProcess leucoanthocyanidin biosynthetic process The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids. go.json http://purl.obolibrary.org/obo/GO_0051557 GO:0002542 biolink:BiologicalProcess Factor XII activation Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade. go.json Hageman factor activation http://purl.obolibrary.org/obo/GO_0002542 GO:0075529 biolink:BiologicalProcess establishment of latency as a circular episome A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure. go.json establishment of latency as a circular plasmid|establishment of circular plasmid latency http://purl.obolibrary.org/obo/GO_0075529 GO:0002543 biolink:BiologicalProcess activation of blood coagulation via clotting cascade Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot. go.json activation of clotting cascade http://purl.obolibrary.org/obo/GO_0002543 GO:0051558 biolink:BiologicalProcess phlobaphene metabolic process The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols. go.json phlobaphene metabolism http://purl.obolibrary.org/obo/GO_0051558 GO:1905961 biolink:CellularComponent protein-cysteine S-palmitoyltransferase complex A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity. go.json Palmitoyltransferase ERF2/SHR5 complex|Palmitoyltransferase ERF2-SHR5 complex http://purl.obolibrary.org/obo/GO_1905961 GO:1905962 biolink:BiologicalProcess glutamatergic neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron. go.json http://purl.obolibrary.org/obo/GO_1905962 GO:1905963 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_1905963 GO:1905964 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_1905964 GO:1905965 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_1905965 GO:0051551 biolink:BiologicalProcess aurone biosynthetic process The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments. go.json benzalcoumaran-3-one biosynthesis|benzalcoumaran-3-one biosynthetic process http://purl.obolibrary.org/obo/GO_0051551 GO:0002548 biolink:BiologicalProcess monocyte chemotaxis The movement of a monocyte in response to an external stimulus. go.json http://purl.obolibrary.org/obo/GO_0002548 GO:0051552 biolink:BiologicalProcess flavone metabolic process The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone). go.json 2-phenyl-4H-1-benzopyran-4-one metabolism|flavone metabolism|2-phenyl-4H-1-benzopyran-4-one metabolic process|2-phenylchromone metabolism|2-phenylchromone metabolic process http://purl.obolibrary.org/obo/GO_0051552 GO:0002549 biolink:BiologicalProcess negative regulation of plasma kallikrein-kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade. go.json inhibition of plasma kallikrein-kinin cascade|downregulation of plasma kallikrein-kinin cascade|down-regulation of plasma kallikrein-kinin cascade|down regulation of plasma kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002549 GO:0075520 biolink:BiologicalProcess actin-dependent intracellular transport of virus The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions. VZ:991 go.json actin-dependent intracellular transport of viral material http://purl.obolibrary.org/obo/GO_0075520 GO:0051550 biolink:BiologicalProcess aurone metabolic process The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides. go.json aurone metabolism|benzalcoumaran-3-one metabolism|benzalcoumaran-3-one metabolic process http://purl.obolibrary.org/obo/GO_0051550 GO:0075521 biolink:BiologicalProcess microtubule-dependent intracellular transport of viral material towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules. VZ:983 go.json microtubule-dependent intracellular transport of viral material to nucleus http://purl.obolibrary.org/obo/GO_0075521 GO:0075511 biolink:BiologicalProcess macropinosome lysis involved in viral entry into host cell Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm. go.json http://purl.obolibrary.org/obo/GO_0075511 GO:0099500 biolink:BiologicalProcess vesicle fusion to plasma membrane Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. go.json http://purl.obolibrary.org/obo/GO_0099500 GO:0051566 biolink:MolecularActivity anthocyanidin-3-glucoside rhamnosyltransferase activity Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP. go.json 3RT activity|anthocyanidin 3-glucoside-rhamnosyltransferase activity http://purl.obolibrary.org/obo/GO_0051566 GO:0002555 biolink:BiologicalProcess histamine secretion by platelet The regulated release of histamine by a platelet or group of platelets. go.json http://purl.obolibrary.org/obo/GO_0002555 GO:0075512 biolink:BiologicalProcess clathrin-dependent endocytosis of virus by host cell Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus. VZ:957 go.json viral penetration via clathrin-mediated endocytosis|viral entry into host cell via clathrin-mediated endocytosis followed by endosome lysis|viral entry into host cell via clathrin-mediated endocytosis|clathrin-mediated endocytosis of virus by host cell http://purl.obolibrary.org/obo/GO_0075512 GO:0051567 biolink:BiologicalProcess histone H3-K9 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone. go.json histone lysine H3 K9 methylation|histone H3 K9 methylation|histone H3K9me http://purl.obolibrary.org/obo/GO_0051567 GO:0099501 biolink:CellularComponent exocytic vesicle membrane The lipid bilayer surrounding an exocytic vesicle. go.json secretory vesicle membrane http://purl.obolibrary.org/obo/GO_0099501 GO:0002556 biolink:BiologicalProcess serotonin secretion by basophil The regulated release of serotonin by a basophil or group of basophils. go.json serotonin release by basophil http://purl.obolibrary.org/obo/GO_0002556 GO:0051564 biolink:BiologicalProcess positive regulation of smooth endoplasmic reticulum calcium ion concentration Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum. go.json smooth endoplasmic reticulum calcium ion concentration elevation|elevation of smooth ER calcium ion concentration|elevation of smooth endoplasmic reticulum calcium ion concentration|elevation of calcium ion concentration in smooth endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0051564 GO:0075513 biolink:BiologicalProcess caveolin-mediated endocytosis of virus by host cell Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus. VZ:976 go.json viral entry into host cell via caveolae-mediated endocytosis|viral penetration via caveolae-mediated endocytosis followed by endosome disruption|viral entry into host cell via caveolin-mediated endocytosis http://purl.obolibrary.org/obo/GO_0075513 GO:0002557 biolink:BiologicalProcess histamine secretion by basophil The regulated release of histamine by a basophil or group of basophils. go.json http://purl.obolibrary.org/obo/GO_0002557 GO:0075514 biolink:BiologicalProcess endosome lysis involved in viral entry into host cell Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm. go.json viral entry into host cell via caveolae-mediated endocytosis followed by endosome lysis http://purl.obolibrary.org/obo/GO_0075514 GO:0051565 biolink:BiologicalProcess negative regulation of smooth endoplasmic reticulum calcium ion concentration Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum. go.json smooth endoplasmic reticulum calcium ion concentration reduction|reduction of calcium ion concentration in smooth ER|reduction of calcium ion concentration in smooth endoplasmic reticulum|reduction of smooth endoplasmic reticulum calcium ion concentration|reduction of smooth ER calcium ion concentration|smooth ER calcium ion concentration reduction http://purl.obolibrary.org/obo/GO_0051565 GO:0002558 biolink:BiologicalProcess type I hypersensitivity mediated by mast cells An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. go.json http://purl.obolibrary.org/obo/GO_0002558 GO:0002551 biolink:BiologicalProcess mast cell chemotaxis The movement of a mast cell in response to an external stimulus. go.json http://purl.obolibrary.org/obo/GO_0002551 GO:0075515 biolink:BiologicalProcess obsolete viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane OBSOLETE. The uptake of a virus into a host cell that begins when material is taken up into plasma membrane caveolae which then pinch off to form endocytic caveolar carriers containing the virus. The caveolar carriers then deliver their viral content to early endosomes, and the process ends when viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane. go.json viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by genetic injection through the endosome membrane http://purl.obolibrary.org/obo/GO_0075515 GO:0075516 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075516 GO:0002552 biolink:BiologicalProcess serotonin secretion by mast cell The regulated release of serotonin by a mast cell or group of mast cells. go.json serotonin release by mast cell http://purl.obolibrary.org/obo/GO_0002552 GO:0051568 biolink:BiologicalProcess histone H3-K4 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone. go.json histone lysine H3 K4 methylation|histone H3 K4 methylation|histone H3K4me http://purl.obolibrary.org/obo/GO_0051568 GO:0002553 biolink:BiologicalProcess histamine secretion by mast cell The regulated release of histamine by a mast cell or group of mast cells. go.json http://purl.obolibrary.org/obo/GO_0002553 GO:0075517 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075517 GO:0051569 biolink:BiologicalProcess regulation of histone H3-K4 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. go.json http://purl.obolibrary.org/obo/GO_0051569 GO:0075518 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075518 GO:0002554 biolink:BiologicalProcess serotonin secretion by platelet The regulated release of serotonin by a platelet or group of platelets. go.json serotonin release by platelet http://purl.obolibrary.org/obo/GO_0002554 GO:0075519 biolink:BiologicalProcess microtubule-dependent intracellular transport of viral material The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus. go.json http://purl.obolibrary.org/obo/GO_0075519 GO:0002550 biolink:BiologicalProcess positive regulation of plasma kallikrein-kinin cascade Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade. go.json activation of plasma kallikrein-kinin cascade|stimulation of plasma kallikrein-kinin cascade|upregulation of plasma kallikrein-kinin cascade|up-regulation of plasma kallikrein-kinin cascade|up regulation of plasma kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002550 GO:0099508 biolink:MolecularActivity voltage-gated ion channel activity involved in regulation of presynaptic membrane potential Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse. go.json voltage gated ion channel activity involved in regulation of presynaptic membrane potential|voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential|voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099508 goslim_synapse GO:0099509 biolink:BiologicalProcess regulation of presynaptic cytosolic calcium ion concentration Any process that regulates the concentration of calcium in the presynaptic cytosol. go.json regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099509 goslim_synapse GO:0099506 biolink:BiologicalProcess synaptic vesicle transport along actin filament The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors. go.json http://purl.obolibrary.org/obo/GO_0099506 goslim_synapse GO:0099507 biolink:MolecularActivity ligand-gated ion channel activity involved in regulation of presynaptic membrane potential Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. go.json ligand-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|ligand gated ion channel activity involved in regulation of presynaptic membrane potential|ligand-dependent ion channel activity involved in regulation of presynaptic membrane potential|ligand-gated ion channel activity involved in regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099507 goslim_synapse GO:0051562 biolink:BiologicalProcess negative regulation of mitochondrial calcium ion concentration Any process that decreases the concentration of calcium ions in mitochondria. go.json reduction of mitochondrial calcium ion concentration|mitochondrial calcium ion concentration reduction|reduction of calcium ion concentration in mitochondrion|reduction of calcium ion concentration in mitochondria http://purl.obolibrary.org/obo/GO_0051562 GO:0099504 biolink:BiologicalProcess synaptic vesicle cycle A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters. go.json http://purl.obolibrary.org/obo/GO_0099504 goslim_synapse GO:0002559 biolink:BiologicalProcess type I hypersensitivity mediated by basophils An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. go.json http://purl.obolibrary.org/obo/GO_0002559 GO:0051563 biolink:BiologicalProcess smooth endoplasmic reticulum calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings. go.json smooth ER calcium ion homeostasis|regulation of smooth ER calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration regulation|smooth ER calcium ion concentration regulation|calcium ion homeostasis in smooth endoplasmic reticulum|regulation of calcium ion concentration in smooth ER|regulation of calcium ion concentration in smooth endoplasmic reticulum|calcium ion homeostasis in smooth ER|regulation of smooth endoplasmic reticulum calcium ion concentration http://purl.obolibrary.org/obo/GO_0051563 GO:0099505 biolink:BiologicalProcess regulation of presynaptic membrane potential Any process that modulates the potential difference across a presynaptic membrane. go.json regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099505 goslim_synapse GO:0051560 biolink:BiologicalProcess mitochondrial calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings. go.json mitochondrial calcium ion concentration regulation|calcium ion homeostasis in mitochondria|regulation of calcium ion concentration in mitochondria|regulation of mitochondrial calcium ion concentration|regulation of calcium ion concentration in mitochondrion|calcium ion homeostasis in mitochondrion http://purl.obolibrary.org/obo/GO_0051560 GO:0099502 biolink:BiologicalProcess calcium-dependent activation of synaptic vesicle fusion The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane. go.json http://purl.obolibrary.org/obo/GO_0099502 goslim_synapse GO:0075510 biolink:BiologicalProcess macropinocytosis involved in viral entry into host cell Any macropinocytosis that is involved in the uptake of a virus into a host cell. VZ:800 go.json viral entry into host cell via macropinocytosis http://purl.obolibrary.org/obo/GO_0075510 GO:0099503 biolink:CellularComponent secretory vesicle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. go.json http://purl.obolibrary.org/obo/GO_0099503 goslim_drosophila GO:0051561 biolink:BiologicalProcess positive regulation of mitochondrial calcium ion concentration Any process that increases the concentration of calcium ions in mitochondria. go.json elevation of calcium ion concentration in mitochondrion|mitochondrial calcium ion concentration elevation|elevation of calcium ion concentration in mitochondria|elevation of mitochondrial calcium ion concentration http://purl.obolibrary.org/obo/GO_0051561 GO:0051577 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051577 GO:0002522 biolink:BiologicalProcess leukocyte migration involved in immune response The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. go.json leukocyte trafficking during immune response|immune cell migration during immune response|leucocyte migration during immune response|leucocyte trafficking during immune response|immune cell trafficking during immune response http://purl.obolibrary.org/obo/GO_0002522 GO:0051578 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051578 GO:0002523 biolink:BiologicalProcess leukocyte migration involved in inflammatory response The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. go.json leukocyte trafficking during inflammatory response|immune cell migration during inflammatory response|leucocyte migration during inflammatory response|leukocyte migration during inflammatory response|leucocyte trafficking during inflammatory response|immune cell trafficking during inflammatory response http://purl.obolibrary.org/obo/GO_0002523 GO:0002524 biolink:BiologicalProcess hypersensitivity An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. Wikipedia:Hypersensitivity go.json hypersensitivity response http://purl.obolibrary.org/obo/GO_0002524 GO:0051575 biolink:MolecularActivity 5'-deoxyribose-5-phosphate lyase activity Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site. go.json dRP lyase activity|5'-deoxyribose phosphate activity|dRPase activity http://purl.obolibrary.org/obo/GO_0051575 GO:0051576 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051576 GO:0002525 biolink:BiologicalProcess acute inflammatory response to non-antigenic stimulus An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma. go.json http://purl.obolibrary.org/obo/GO_0002525 GO:0002520 biolink:BiologicalProcess immune system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. go.json http://purl.obolibrary.org/obo/GO_0002520 goslim_drosophila GO:0051579 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051579 GO:0002521 biolink:BiologicalProcess leukocyte differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. go.json leucocyte differentiation|immune cell differentiation http://purl.obolibrary.org/obo/GO_0002521 GO:0051570 biolink:BiologicalProcess regulation of histone H3-K9 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. go.json http://purl.obolibrary.org/obo/GO_0051570 GO:0051573 biolink:BiologicalProcess negative regulation of histone H3-K9 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. go.json down-regulation of histone H3-K9 methylation|down regulation of histone H3-K9 methylation|inhibition of histone H3-K9 methylation|downregulation of histone H3-K9 methylation http://purl.obolibrary.org/obo/GO_0051573 GO:0002526 biolink:BiologicalProcess acute inflammatory response Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. go.json http://purl.obolibrary.org/obo/GO_0002526 GO:0051574 biolink:BiologicalProcess positive regulation of histone H3-K9 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. go.json stimulation of histone H3-K9 methylation|upregulation of histone H3-K9 methylation|up-regulation of histone H3-K9 methylation|up regulation of histone H3-K9 methylation|activation of histone H3-K9 methylation http://purl.obolibrary.org/obo/GO_0051574 GO:0002527 biolink:BiologicalProcess vasodilation involved in acute inflammatory response An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response. go.json vasodilation during acute inflammatory response http://purl.obolibrary.org/obo/GO_0002527 GO:0002528 biolink:BiologicalProcess regulation of vascular permeability involved in acute inflammatory response Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response. go.json regulation of vascular permeability during acute inflammatory response http://purl.obolibrary.org/obo/GO_0002528 GO:0051571 biolink:BiologicalProcess positive regulation of histone H3-K4 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. go.json up regulation of histone H3-K4 methylation|activation of histone H3-K4 methylation|stimulation of histone H3-K4 methylation|upregulation of histone H3-K4 methylation|up-regulation of histone H3-K4 methylation http://purl.obolibrary.org/obo/GO_0051571 GO:0002529 biolink:BiologicalProcess regulation of plasma kallikrein-kinin cascade Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade. go.json http://purl.obolibrary.org/obo/GO_0002529 GO:0051572 biolink:BiologicalProcess negative regulation of histone H3-K4 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. go.json down-regulation of histone H3-K4 methylation|down regulation of histone H3-K4 methylation|inhibition of histone H3-K4 methylation|downregulation of histone H3-K4 methylation http://purl.obolibrary.org/obo/GO_0051572 GO:0002533 biolink:BiologicalProcess lysosomal enzyme secretion involved in inflammatory response The regulated release of lysosomal enzymes by a cell as part of an inflammatory response. go.json lysosomal enzyme secretion involved in acute inflammatory response|secretion of lysosomal enzymes involved in acute inflammatory response|secretion of lysosomal enzymes involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002533 GO:0051588 biolink:BiologicalProcess regulation of neurotransmitter transport Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json http://purl.obolibrary.org/obo/GO_0051588 GO:0051589 biolink:BiologicalProcess negative regulation of neurotransmitter transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json inhibition of neurotransmitter transport|down-regulation of neurotransmitter transport|downregulation of neurotransmitter transport|down regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051589 GO:0002534 biolink:BiologicalProcess cytokine production involved in inflammatory response The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go.json cytokine production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002534 gocheck_do_not_annotate GO:0002535 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002535 GO:0051586 biolink:BiologicalProcess positive regulation of dopamine uptake involved in synaptic transmission Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell. go.json up-regulation of dopamine uptake involved in synaptic transmission|up regulation of dopamine uptake involved in synaptic transmission|activation of dopamine uptake involved in synaptic transmission|positive regulation of dopamine import involved in synaptic transmission|stimulation of dopamine uptake involved in synaptic transmission|upregulation of dopamine uptake involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051586 GO:0002536 biolink:BiologicalProcess respiratory burst involved in inflammatory response A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels. go.json respiratory burst involved in acute inflammatory response|oxidative burst during acute inflammatory response|production of reactive oxygen species during acute inflammatory response http://purl.obolibrary.org/obo/GO_0002536 GO:0051587 biolink:BiologicalProcess inhibition of dopamine uptake involved in synaptic transmission Any process that prevents the activation of the directed movement of dopamine into a cell. go.json inhibition of dopamine import involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051587 GO:0002530 biolink:BiologicalProcess regulation of systemic arterial blood pressure involved in acute-phase response Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein. go.json regulation of systemic arterial blood pressure during acute phase response|blood pressure regulation during acute phase response http://purl.obolibrary.org/obo/GO_0002530 GO:0002531 biolink:BiologicalProcess regulation of heart contraction involved in acute-phase response Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein. go.json regulation of heart contraction during acute phase response|regulation of cardiac contraction during acute phase response http://purl.obolibrary.org/obo/GO_0002531 GO:0002532 biolink:BiologicalProcess production of molecular mediator involved in inflammatory response The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. go.json production of molecular mediator involved in acute inflammatory response|production of cellular mediator of acute inflammation http://purl.obolibrary.org/obo/GO_0002532 GO:0051580 biolink:BiologicalProcess regulation of neurotransmitter uptake Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. go.json regulation of neurotransmitter import|regulation of neurotransmitter reuptake http://purl.obolibrary.org/obo/GO_0051580 goslim_synapse GO:0051581 biolink:BiologicalProcess negative regulation of neurotransmitter uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. go.json down regulation of neurotransmitter uptake|downregulation of neurotransmitter uptake|down-regulation of neurotransmitter uptake|negative regulation of neurotransmitter import http://purl.obolibrary.org/obo/GO_0051581 GO:0051584 biolink:BiologicalProcess regulation of dopamine uptake involved in synaptic transmission Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell. go.json regulation of dopamine import involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051584 GO:0002537 biolink:BiologicalProcess nitric oxide production involved in inflammatory response The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go.json production of nitric oxide involved in inflammatory response|production of nitric oxide involved in acute inflammatory response|nitric oxide production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002537 GO:0075530 biolink:BiologicalProcess establishment of latency as a linear episome A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure. go.json establishment of linear plasmid latency|establishment of latency as a linear plasmid http://purl.obolibrary.org/obo/GO_0075530 GO:0051585 biolink:BiologicalProcess negative regulation of dopamine uptake involved in synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell. go.json down regulation of dopamine uptake involved in synaptic transmission|downregulation of dopamine uptake involved in synaptic transmission|down-regulation of dopamine uptake involved in synaptic transmission|negative regulation of dopamine import involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051585 GO:0002538 biolink:BiologicalProcess arachidonic acid metabolite production involved in inflammatory response The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels. go.json arachidonic acid metabolite production involved in acute inflammatory response|production of arachidonic acid metabolites involved in acute inflammatory response|production of arachidonic acid metabolites involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002538 GO:0002539 biolink:BiologicalProcess prostaglandin production involved in inflammatory response The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go.json prostaglandin production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002539 GO:0051582 biolink:BiologicalProcess positive regulation of neurotransmitter uptake Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. go.json up-regulation of neurotransmitter uptake|up regulation of neurotransmitter uptake|activation of neurotransmitter uptake|positive regulation of neurotransmitter import|stimulation of neurotransmitter uptake|upregulation of neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0051582 GO:0051583 biolink:BiologicalProcess dopamine uptake involved in synaptic transmission The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. go.json dopamine import involved in synaptic transmission|dopamine reuptake involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051583 GO:1905900 biolink:BiologicalProcess negative regulation of smooth muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. go.json down regulation of smooth muscle tissue development|inhibition of smooth muscle tissue development|down-regulation of smooth muscle tissue development|downregulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905900 GO:1905901 biolink:BiologicalProcess positive regulation of smooth muscle tissue development Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. go.json activation of smooth muscle tissue development|upregulation of smooth muscle tissue development|up regulation of smooth muscle tissue development|up-regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905901 GO:1905902 biolink:BiologicalProcess regulation of mesoderm formation Any process that modulates the frequency, rate or extent of mesoderm formation. go.json http://purl.obolibrary.org/obo/GO_1905902 GO:1905903 biolink:BiologicalProcess negative regulation of mesoderm formation Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. go.json down regulation of mesoderm formation|inhibition of mesoderm formation|down-regulation of mesoderm formation|downregulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905903 GO:1905904 biolink:BiologicalProcess positive regulation of mesoderm formation Any process that activates or increases the frequency, rate or extent of mesoderm formation. go.json upregulation of mesoderm formation|up regulation of mesoderm formation|activation of mesoderm formation|up-regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905904 GO:1905905 biolink:BiologicalProcess pharyngeal gland morphogenesis The developmental process by which a pharyngeal gland is generated and organized. go.json glandulae pharyngeae morphogenesis|pharynx gland morphogenesis http://purl.obolibrary.org/obo/GO_1905905 GO:1905906 biolink:BiologicalProcess regulation of amyloid fibril formation Any process that modulates the frequency, rate or extent of amyloid fibril formation. go.json regulation of amyloid fibril assembly|regulation of amyloid structure formation|regulation of amyloid structure assembly http://purl.obolibrary.org/obo/GO_1905906 GO:1905907 biolink:BiologicalProcess negative regulation of amyloid fibril formation Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation. go.json down regulation of amyloid structure assembly|downregulation of amyloid fibril formation|downregulation of amyloid fibril assembly|down-regulation of amyloid structure assembly|negative regulation of amyloid structure assembly|inhibition of amyloid structure formation|down regulation of amyloid fibril formation|inhibition of amyloid structure assembly|negative regulation of amyloid structure formation|inhibition of amyloid fibril assembly|down-regulation of amyloid structure formation|inhibition of amyloid fibril formation|down-regulation of amyloid fibril formation|down regulation of amyloid structure formation|downregulation of amyloid structure assembly|negative regulation of amyloid fibril assembly|down-regulation of amyloid fibril assembly|downregulation of amyloid structure formation|down regulation of amyloid fibril assembly http://purl.obolibrary.org/obo/GO_1905907 GO:1905908 biolink:BiologicalProcess positive regulation of amyloid fibril formation Any process that activates or increases the frequency, rate or extent of amyloid fibril formation. go.json up regulation of amyloid fibril formation|up regulation of amyloid structure formation|activation of amyloid structure assembly|upregulation of amyloid structure assembly|up-regulation of amyloid fibril assembly|positive regulation of amyloid structure formation|activation of amyloid fibril formation|up-regulation of amyloid fibril formation|up regulation of amyloid fibril assembly|positive regulation of amyloid structure assembly|upregulation of amyloid structure formation|positive regulation of amyloid fibril assembly|activation of amyloid structure formation|up regulation of amyloid structure assembly|upregulation of amyloid fibril formation|upregulation of amyloid fibril assembly|up-regulation of amyloid structure assembly|activation of amyloid fibril assembly|up-regulation of amyloid structure formation http://purl.obolibrary.org/obo/GO_1905908 GO:1905909 biolink:BiologicalProcess regulation of dauer entry Any process that modulates the frequency, rate or extent of dauer entry. go.json regulation of nematode entry into dormancy http://purl.obolibrary.org/obo/GO_1905909 GO:0051500 biolink:MolecularActivity D-tyrosyl-tRNA(Tyr) deacylase activity Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA. go.json http://purl.obolibrary.org/obo/GO_0051500 GO:0051501 biolink:BiologicalProcess diterpene phytoalexin metabolic process The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units. go.json diterpene phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0051501 GO:0051504 biolink:BiologicalProcess diterpene phytoalexin precursor biosynthetic process pathway A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins. MetaCyc:PWY-2981 go.json diterpene phytoalexin precursor formation pathway|diterpene phytoalexin precursor anabolism pathway|diterpene phytoalexin precursor synthesis pathway http://purl.obolibrary.org/obo/GO_0051504 GO:0051505 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051505 GO:0051502 biolink:BiologicalProcess diterpene phytoalexin biosynthetic process The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses. go.json diterpene phytoalexin synthesis|diterpene phytoalexin formation|diterpene phytoalexin biosynthesis|diterpene phytoalexin anabolism http://purl.obolibrary.org/obo/GO_0051502 GO:0051503 biolink:BiologicalProcess adenine nucleotide transport The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json http://purl.obolibrary.org/obo/GO_0051503 GO:0051508 biolink:MolecularActivity stigmasterol UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol. RHEA:61828|MetaCyc:RXN-12126 go.json http://purl.obolibrary.org/obo/GO_0051508 GO:0051509 biolink:MolecularActivity tomatidine UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine. go.json http://purl.obolibrary.org/obo/GO_0051509 GO:0051506 biolink:MolecularActivity ergosterol UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol. RHEA:61836|MetaCyc:RXN-16975) go.json http://purl.obolibrary.org/obo/GO_0051506 GO:0051507 biolink:MolecularActivity beta-sitosterol UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol. RHEA:61832|MetaCyc:RXN-12128 go.json http://purl.obolibrary.org/obo/GO_0051507 GO:1905910 biolink:BiologicalProcess negative regulation of dauer entry Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry. go.json down-regulation of dauer entry|downregulation of nematode entry into dormancy|down regulation of dauer entry|down regulation of nematode entry into dormancy|downregulation of dauer entry|inhibition of dauer entry|inhibition of nematode entry into dormancy|negative regulation of nematode entry into dormancy|down-regulation of nematode entry into dormancy http://purl.obolibrary.org/obo/GO_1905910 GO:1905911 biolink:BiologicalProcess positive regulation of dauer entry Any process that activates or increases the frequency, rate or extent of dauer entry. go.json upregulation of nematode entry into dormancy|up regulation of dauer entry|activation of dauer entry|positive regulation of nematode entry into dormancy|up regulation of nematode entry into dormancy|upregulation of dauer entry|up-regulation of nematode entry into dormancy|activation of nematode entry into dormancy|up-regulation of dauer entry http://purl.obolibrary.org/obo/GO_1905911 GO:1905912 biolink:BiologicalProcess regulation of calcium ion export across plasma membrane Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane. go.json regulation of calcium ion export from cell|regulation of calcium ion efflux from cell http://purl.obolibrary.org/obo/GO_1905912 GO:1905913 biolink:BiologicalProcess negative regulation of calcium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane. go.json down regulation of calcium ion efflux from cell|downregulation of calcium ion export from cell|inhibition of calcium ion efflux from cell|negative regulation of calcium ion efflux from cell|down-regulation of calcium ion efflux from cell|down regulation of calcium ion export from cell|inhibition of calcium ion export from cell|down-regulation of calcium ion export from cell|negative regulation of calcium ion export from cell|downregulation of calcium ion efflux from cell http://purl.obolibrary.org/obo/GO_1905913 GO:1905914 biolink:BiologicalProcess positive regulation of calcium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane. go.json positive regulation of calcium ion export from cell|up regulation of calcium ion export from cell|up-regulation of calcium ion export from cell|upregulation of calcium ion efflux from cell|activation of calcium ion export from cell|positive regulation of calcium ion efflux from cell|up regulation of calcium ion efflux from cell|upregulation of calcium ion export from cell|up-regulation of calcium ion efflux from cell|activation of calcium ion efflux from cell http://purl.obolibrary.org/obo/GO_1905914 GO:1905915 biolink:BiologicalProcess regulation of cell differentiation involved in phenotypic switching Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching. go.json http://purl.obolibrary.org/obo/GO_1905915 GO:1905916 biolink:BiologicalProcess negative regulation of cell differentiation involved in phenotypic switching Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching. go.json down-regulation of cell differentiation involved in phenotypic switching|down regulation of cell differentiation involved in phenotypic switching|inhibition of cell differentiation involved in phenotypic switching|downregulation of cell differentiation involved in phenotypic switching http://purl.obolibrary.org/obo/GO_1905916 GO:1905917 biolink:BiologicalProcess positive regulation of cell differentiation involved in phenotypic switching Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching. go.json upregulation of cell differentiation involved in phenotypic switching|up-regulation of cell differentiation involved in phenotypic switching|up regulation of cell differentiation involved in phenotypic switching|activation of cell differentiation involved in phenotypic switching http://purl.obolibrary.org/obo/GO_1905917 GO:1905918 biolink:BiologicalProcess regulation of CoA-transferase activity Any process that modulates the frequency, rate or extent of CoA-transferase activity. go.json http://purl.obolibrary.org/obo/GO_1905918 GO:1905919 biolink:BiologicalProcess negative regulation of CoA-transferase activity Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity. go.json down regulation of CoA-transferase activity|inhibition of CoA-transferase activity|down-regulation of CoA-transferase activity|downregulation of CoA-transferase activity http://purl.obolibrary.org/obo/GO_1905919 GO:0036093 biolink:BiologicalProcess germ cell proliferation The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. go.json http://purl.obolibrary.org/obo/GO_0036093 GO:0036094 biolink:MolecularActivity small molecule binding Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule. go.json http://purl.obolibrary.org/obo/GO_0036094 goslim_agr|goslim_flybase_ribbon GO:0036095 biolink:BiologicalProcess obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go.json transcriptional activation of genes involved in invasive growth http://purl.obolibrary.org/obo/GO_0036095 GO:0036096 biolink:MolecularActivity obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA. go.json exonucleolytic trimming to generate 3' end of miRNA from pre-miRNA|3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0036096 GO:0036097 biolink:BiologicalProcess obsolete pre-miRNA 3'-end processing OBSOLETE. Any process involved in forming the mature 3' end of a miRNA from a pre-miRNA. go.json pre-miRNA 3'-end processing|microRNA 3'-end processing|miRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0036097 GO:0036098 biolink:BiologicalProcess male germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of male germ-line stem cells. go.json http://purl.obolibrary.org/obo/GO_0036098 GO:0036099 biolink:BiologicalProcess female germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of female germ-line stem cells. go.json http://purl.obolibrary.org/obo/GO_0036099 GO:0036090 biolink:BiologicalProcess cleavage furrow ingression Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed. go.json cleavage furrow contraction http://purl.obolibrary.org/obo/GO_0036090 GO:0036091 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go.json http://purl.obolibrary.org/obo/GO_0036091 GO:0036092 biolink:BiologicalProcess phosphatidylinositol-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position. go.json phosphatidylinositol-3-phosphate biosynthesis|phosphatidylinositol-3-phosphate formation|phosphatidylinositol-3-phosphate anabolism|PtdIns3P biosynthesis|PI(3)P biosynthesis|phosphatidylinositol-3-phosphate synthesis http://purl.obolibrary.org/obo/GO_0036092 GO:0036082 biolink:MolecularActivity extracellular phenylacetaldehyde-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts. go.json ionotropic phenylacetaldehyde receptor activity http://purl.obolibrary.org/obo/GO_0036082 GO:0036083 biolink:BiologicalProcess obsolete positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go.json http://purl.obolibrary.org/obo/GO_0036083 GO:0036084 biolink:BiologicalProcess GDP-fucose import into endoplasmic reticulum lumen The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. go.json GDP-fucose import into endoplasmic reticulum|GDP-fucose transport into endoplasmic reticulum lumen|GDP-fucose transport across endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0036084 GO:0036085 biolink:BiologicalProcess GDP-fucose import into Golgi lumen The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. go.json GDP-fucose transport across Golgi membrane|GDP-fucose import into Golgi|GDP-fucose transport into Golgi lumen http://purl.obolibrary.org/obo/GO_0036085 GO:0036086 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions. go.json positive regulation of transcription from RNA polymerase II promoter in response to iron deficiency http://purl.obolibrary.org/obo/GO_0036086 GO:0036087 biolink:CellularComponent glutathione synthase complex A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer. go.json glutathione synthetase complex http://purl.obolibrary.org/obo/GO_0036087 GO:0036088 biolink:BiologicalProcess D-serine catabolic process The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. go.json D-serine degradation|D-serine breakdown|D-serine catabolism http://purl.obolibrary.org/obo/GO_0036088 GO:0036089 biolink:BiologicalProcess cleavage furrow formation Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell. go.json cleavage furrow positioning http://purl.obolibrary.org/obo/GO_0036089 GO:0002742 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002742 GO:0002743 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002743 GO:0002744 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002744 GO:0002745 biolink:BiologicalProcess antigen processing and presentation initiated by receptor mediated uptake of antigen Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor. go.json http://purl.obolibrary.org/obo/GO_0002745 GO:0002740 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002740 GO:0002741 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002741 GO:0085008 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from microneme OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the microneme, a small, elongated secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085008 GO:0061040 biolink:BiologicalProcess female gonad morphogenesis The process in which a female gonad is generated and organized. go.json ovary morphogenesis http://purl.obolibrary.org/obo/GO_0061040 GO:1905890 biolink:BiologicalProcess regulation of cellular response to very-low-density lipoprotein particle stimulus Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. go.json regulation of cellular response to VLDL particle stimulus http://purl.obolibrary.org/obo/GO_1905890 GO:0085009 biolink:BiologicalProcess obsolete interaction with host mediated by symbiont secreted substance released from Maurer's cleft OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via Maurer's cleft. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json interaction with host mediated by symbiont secreted substance released from Maurers cleft http://purl.obolibrary.org/obo/GO_0085009 GO:0061041 biolink:BiologicalProcess regulation of wound healing Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. go.json http://purl.obolibrary.org/obo/GO_0061041 GO:0085006 biolink:BiologicalProcess obsolete interaction with host mediated by symbiont secreted substance released from symbiont-containing vacuole OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via a symbiont-containing vacuole, a specialized sac within the host in which the symbiont resides. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json interaction with host mediated by symbiont secreted substance released from parasitophorous vacuole http://purl.obolibrary.org/obo/GO_0085006 GO:0061042 biolink:BiologicalProcess vascular wound healing Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. go.json http://purl.obolibrary.org/obo/GO_0061042 GO:1905891 biolink:BiologicalProcess regulation of cellular response to thapsigargin Any process that modulates the frequency, rate or extent of cellular response to thapsigargin. go.json http://purl.obolibrary.org/obo/GO_1905891 GO:0061043 biolink:BiologicalProcess regulation of vascular wound healing Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. go.json http://purl.obolibrary.org/obo/GO_0061043 GO:1905892 biolink:BiologicalProcess negative regulation of cellular response to thapsigargin Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to thapsigargin. go.json down-regulation of cellular response to thapsigargin|down regulation of cellular response to thapsigargin|inhibition of cellular response to thapsigargin|downregulation of cellular response to thapsigargin http://purl.obolibrary.org/obo/GO_1905892 GO:0085007 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from rhoptry OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the rhoptry, a large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085007 GO:0061044 biolink:BiologicalProcess negative regulation of vascular wound healing Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. go.json http://purl.obolibrary.org/obo/GO_0061044 GO:0085004 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from haustorium OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the haustorium, a projection from a cell or tissue that penetrates the host's cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085004 GO:1905893 biolink:BiologicalProcess positive regulation of cellular response to thapsigargin Any process that activates or increases the frequency, rate or extent of cellular response to thapsigargin. go.json upregulation of cellular response to thapsigargin|up-regulation of cellular response to thapsigargin|up regulation of cellular response to thapsigargin|activation of cellular response to thapsigargin http://purl.obolibrary.org/obo/GO_1905893 GO:0061045 biolink:BiologicalProcess negative regulation of wound healing Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. go.json http://purl.obolibrary.org/obo/GO_0061045 GO:0085005 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from invasive hyphae OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via invasive hyphae. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085005 GO:1905894 biolink:BiologicalProcess regulation of cellular response to tunicamycin Any process that modulates the frequency, rate or extent of cellular response to tunicamycin. go.json http://purl.obolibrary.org/obo/GO_1905894 GO:1905884 biolink:BiologicalProcess negative regulation of triglyceride transport Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport. go.json inhibition of triacylglycerol transport|down regulation of triglyceride transport|downregulation of triacylglycerol transport|inhibition of triglyceride transport|down-regulation of triglyceride transport|down-regulation of triacylglycerol transport|negative regulation of triacylglycerol transport|down regulation of triacylglycerol transport|downregulation of triglyceride transport http://purl.obolibrary.org/obo/GO_1905884 GO:0061046 biolink:BiologicalProcess regulation of branching involved in lung morphogenesis Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. go.json http://purl.obolibrary.org/obo/GO_0061046 GO:0085002 biolink:BiologicalProcess obsolete interaction with host mediated by secreted substance released by symbiont from symbiotic structure OBSOLETE. An interaction with the host organism mediated by a symbiont secreted substance released by specialized structures generated in either organisms as a result of the symbiotic interaction. The term host is used for the larger (macro) of the two members of a symbiosis. go.json http://purl.obolibrary.org/obo/GO_0085002 GO:0085003 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from stylet OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085003 GO:1905885 biolink:BiologicalProcess positive regulation of triglyceride transport Any process that activates or increases the frequency, rate or extent of triglyceride transport. go.json up-regulation of triacylglycerol transport|upregulation of triglyceride transport|up regulation of triacylglycerol transport|activation of triacylglycerol transport|positive regulation of triacylglycerol transport|up regulation of triglyceride transport|upregulation of triacylglycerol transport|up-regulation of triglyceride transport|activation of triglyceride transport http://purl.obolibrary.org/obo/GO_1905885 GO:0061047 biolink:BiologicalProcess positive regulation of branching involved in lung morphogenesis Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. go.json http://purl.obolibrary.org/obo/GO_0061047 GO:0085000 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type V secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type V secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085000 GO:1905886 biolink:BiologicalProcess chromatin remodeling involved in meiosis I Any chromatin remodeling that is involved in meiosis I. go.json meiosis-specific chromatin remodeling|chromatin modeling involved in meiosis I|chromatin modelling involved in meiosis I|chromatin remodelling involved in meiosis I http://purl.obolibrary.org/obo/GO_1905886 GO:0061048 biolink:BiologicalProcess negative regulation of branching involved in lung morphogenesis Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. go.json http://purl.obolibrary.org/obo/GO_0061048 GO:0061049 biolink:BiologicalProcess cell growth involved in cardiac muscle cell development The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go.json cardiac muscle cell hypertrophy|cardiomyocyte growth|heart muscle cell growth http://purl.obolibrary.org/obo/GO_0061049 GO:1905887 biolink:BiologicalProcess autoinducer AI-2 transmembrane transport The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing. go.json AI-2 transmembrane transport|autoinducer 2 transmembrane transport|(2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol transmembrane transport http://purl.obolibrary.org/obo/GO_1905887 GO:0085001 biolink:BiologicalProcess formation of stylet for nutrient acquisition The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json formation by symbiont of stylet for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0085001 GO:1905888 biolink:BiologicalProcess negative regulation of cellular response to very-low-density lipoprotein particle stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. go.json down-regulation of cellular response to very-low-density lipoprotein particle stimulus|down-regulation of cellular response to VLDL particle stimulus|negative regulation of cellular response to VLDL particle stimulus|down regulation of cellular response to very-low-density lipoprotein particle stimulus|down regulation of cellular response to VLDL particle stimulus|inhibition of cellular response to very-low-density lipoprotein particle stimulus|downregulation of cellular response to very-low-density lipoprotein particle stimulus|inhibition of cellular response to VLDL particle stimulus|downregulation of cellular response to VLDL particle stimulus http://purl.obolibrary.org/obo/GO_1905888 GO:1905889 biolink:BiologicalProcess positive regulation of cellular response to very-low-density lipoprotein particle stimulus Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. go.json upregulation of cellular response to very-low-density lipoprotein particle stimulus|upregulation of cellular response to VLDL particle stimulus|up-regulation of cellular response to very-low-density lipoprotein particle stimulus|up-regulation of cellular response to VLDL particle stimulus|up regulation of cellular response to very-low-density lipoprotein particle stimulus|up regulation of cellular response to VLDL particle stimulus|activation of cellular response to very-low-density lipoprotein particle stimulus|positive regulation of cellular response to VLDL particle stimulus|activation of cellular response to VLDL particle stimulus http://purl.obolibrary.org/obo/GO_1905889 GO:0002746 biolink:BiologicalProcess antigen processing and presentation following pinocytosis Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis. go.json http://purl.obolibrary.org/obo/GO_0002746 GO:0002747 biolink:BiologicalProcess antigen processing and presentation following phagocytosis Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis. go.json http://purl.obolibrary.org/obo/GO_0002747 GO:0002748 biolink:BiologicalProcess antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR). go.json antigen processing and presentation initiated by PAMP receptor mediated uptake of antigen|antigen processing and presentation initiated by PRR mediated uptake of antigen http://purl.obolibrary.org/obo/GO_0002748 GO:0002749 biolink:BiologicalProcess antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR). go.json antigen processing and presentation initiated by TLR mediated phagocytosis of antigen http://purl.obolibrary.org/obo/GO_0002749 GO:0002753 biolink:BiologicalProcess cytoplasmic pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. go.json cytoplasmic PRR signaling pathway|cytoplasmic pattern recognition receptor signalling pathway|cytoplasmic PAMP receptor signaling pathway|cytoplasmic pathogen receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002753 GO:0002754 biolink:BiologicalProcess intracellular endosomal pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of an intracellular vesicle pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. go.json intracellular vesicle PAMP receptor signaling pathway|intracellular vesicle pattern recognition receptor signaling pathway|intracellular vesicle pathogen receptor signaling pathway|intracellular vesicle PRR signaling pathway|intracellular vesicle pattern recognition receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002754 GO:0002755 biolink:BiologicalProcess MyD88-dependent toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go.json MyD88-dependent TLR signaling pathway|MyD88-dependent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002755 GO:0002756 biolink:BiologicalProcess MyD88-independent toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go.json MyD88-independent toll-like receptor signalling pathway|MyD88-independent TLR signaling pathway http://purl.obolibrary.org/obo/GO_0002756 GO:0002750 biolink:BiologicalProcess antigen processing and presentation following macropinocytosis Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis. go.json http://purl.obolibrary.org/obo/GO_0002750 GO:0002751 biolink:BiologicalProcess antigen processing and presentation following receptor mediated endocytosis Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis. go.json http://purl.obolibrary.org/obo/GO_0002751 GO:0002752 biolink:BiologicalProcess cell surface pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. go.json cell surface PAMP receptor signaling pathway|cell surface pathogen receptor signaling pathway|cell surface PRR signaling pathway|cell surface pattern recognition receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002752 GO:0061030 biolink:BiologicalProcess epithelial cell differentiation involved in mammary gland alveolus development The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. go.json http://purl.obolibrary.org/obo/GO_0061030 GO:0061031 biolink:BiologicalProcess endodermal digestive tract morphogenesis The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm. go.json http://purl.obolibrary.org/obo/GO_0061031 GO:0061032 biolink:BiologicalProcess visceral serous pericardium development The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. go.json epicardium development http://purl.obolibrary.org/obo/GO_0061032 GO:0061033 biolink:BiologicalProcess secretion by lung epithelial cell involved in lung growth The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development. go.json fetal lung liquid secretion http://purl.obolibrary.org/obo/GO_0061033 GO:0061034 biolink:BiologicalProcess olfactory bulb mitral cell layer development The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. go.json http://purl.obolibrary.org/obo/GO_0061034 GO:0061035 biolink:BiologicalProcess regulation of cartilage development Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go.json http://purl.obolibrary.org/obo/GO_0061035 GO:1905895 biolink:BiologicalProcess negative regulation of cellular response to tunicamycin Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to tunicamycin. go.json downregulation of cellular response to tunicamycin|down regulation of cellular response to tunicamycin|inhibition of cellular response to tunicamycin|down-regulation of cellular response to tunicamycin http://purl.obolibrary.org/obo/GO_1905895 GO:1905896 biolink:BiologicalProcess positive regulation of cellular response to tunicamycin Any process that activates or increases the frequency, rate or extent of cellular response to tunicamycin. go.json up regulation of cellular response to tunicamycin|up-regulation of cellular response to tunicamycin|activation of cellular response to tunicamycin|upregulation of cellular response to tunicamycin http://purl.obolibrary.org/obo/GO_1905896 GO:0061036 biolink:BiologicalProcess positive regulation of cartilage development Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go.json http://purl.obolibrary.org/obo/GO_0061036 GO:1905897 biolink:BiologicalProcess regulation of response to endoplasmic reticulum stress Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress. go.json regulation of response to ER stress|regulation of cellular response to endoplasmic reticulum stress|regulation of ER stress response http://purl.obolibrary.org/obo/GO_1905897 GO:0061037 biolink:BiologicalProcess negative regulation of cartilage development Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go.json http://purl.obolibrary.org/obo/GO_0061037 GO:1905898 biolink:BiologicalProcess positive regulation of response to endoplasmic reticulum stress Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress. go.json activation of ER stress response|up-regulation of ER stress response|up-regulation of response to ER stress|up-regulation of cellular response to endoplasmic reticulum stress|upregulation of response to endoplasmic reticulum stress|up regulation of cellular response to endoplasmic reticulum stress|up regulation of response to ER stress|upregulation of ER stress response|activation of response to ER stress|activation of cellular response to endoplasmic reticulum stress|positive regulation of response to ER stress|positive regulation of cellular response to endoplasmic reticulum stress|positive regulation of ER stress response|upregulation of cellular response to endoplasmic reticulum stress|up regulation of response to endoplasmic reticulum stress|upregulation of response to ER stress|up regulation of ER stress response|activation of response to endoplasmic reticulum stress|up-regulation of response to endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_1905898 GO:0061038 biolink:BiologicalProcess uterus morphogenesis The process in which anatomical structures of the uterus are generated and organized. go.json http://purl.obolibrary.org/obo/GO_0061038 GO:1905899 biolink:BiologicalProcess regulation of smooth muscle tissue development Any process that modulates the frequency, rate or extent of smooth muscle tissue development. go.json http://purl.obolibrary.org/obo/GO_1905899 GO:0061039 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061039 GO:0002757 biolink:BiologicalProcess immune response-activating signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response. go.json http://purl.obolibrary.org/obo/GO_0002757 GO:0002758 biolink:BiologicalProcess innate immune response-activating signal transduction A series of molecular signals generated as a consequence of a pathogen or microbial effector binding to a plant 'resistance-gene' receptor to activate a plant immune response, usually plant-type hypersensitive response. go.json defense response signalling pathway, resistance gene-dependent|defence response signalling pathway, resistance gene-dependent|defense response signaling pathway, resistance gene-independent|defence response signaling pathway, resistance gene-independent|effector-triggered immune signaling|defence response signalling pathway, resistance gene-independent|effector triggered immunity|effector-triggered immunity|defense response signaling pathway, resistance gene-dependent|defence response signaling pathway, resistance gene-dependent http://purl.obolibrary.org/obo/GO_0002758 GO:0002759 biolink:BiologicalProcess regulation of antimicrobial humoral response Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response. go.json http://purl.obolibrary.org/obo/GO_0002759 GO:0002720 biolink:BiologicalProcess positive regulation of cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. go.json activation of cytokine production during immune response|up regulation of cytokine production during immune response|positive regulation of cytokine biosynthetic process involved in immune response|up-regulation of cytokine production during immune response|positive regulation of cytokine secretion involved in immune response|positive regulation of cytokine production during immune response|upregulation of cytokine production during immune response|stimulation of cytokine production during immune response http://purl.obolibrary.org/obo/GO_0002720 GO:0099632 biolink:BiologicalProcess protein transport within plasma membrane A process in which protein is transported from one region of the plasma membrane to another. go.json http://purl.obolibrary.org/obo/GO_0099632 GO:0099633 biolink:BiologicalProcess protein localization to postsynaptic specialization membrane A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density). go.json protein localisation in postsynaptic specialization membrane http://purl.obolibrary.org/obo/GO_0099633 GO:0002721 biolink:BiologicalProcess regulation of B cell cytokine production Any process that modulates the frequency, rate, or extent of B cell cytokine production. go.json regulation of B-lymphocyte cytokine production|regulation of B-cell cytokine production|regulation of B lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002721 GO:0002722 biolink:BiologicalProcess negative regulation of B cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production. go.json down-regulation of B cell cytokine production|negative regulation of B-cell cytokine production|negative regulation of B lymphocyte cytokine production|negative regulation of B-lymphocyte cytokine production|downregulation of B cell cytokine production|down regulation of B cell cytokine production|inhibition of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002722 GO:0099630 biolink:BiologicalProcess postsynaptic neurotransmitter receptor cycle The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. go.json http://purl.obolibrary.org/obo/GO_0099630 GO:0002723 biolink:BiologicalProcess positive regulation of B cell cytokine production Any process that activates or increases the frequency, rate, or extent of B cell cytokine production. go.json upregulation of B cell cytokine production|stimulation of B cell cytokine production|up regulation of B cell cytokine production|positive regulation of B-cell cytokine production|positive regulation of B lymphocyte cytokine production|activation of B cell cytokine production|up-regulation of B cell cytokine production|positive regulation of B-lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002723 GO:0099631 biolink:CellularComponent postsynaptic endocytic zone cytoplasmic component The cytoplasmic component of the postsynaptic endocytic zone. go.json postsynaptic endocytic zone cytoplasmic component http://purl.obolibrary.org/obo/GO_0099631 goslim_synapse GO:0061060 biolink:BiologicalProcess negative regulation of peptidoglycan recognition protein signaling pathway Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. go.json negative regulation of peptidoglycan recognition protein signalling pathway http://purl.obolibrary.org/obo/GO_0061060 GO:0061061 biolink:BiologicalProcess muscle structure development The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. go.json http://purl.obolibrary.org/obo/GO_0061061 goslim_drosophila GO:0061062 biolink:BiologicalProcess regulation of nematode larval development Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go.json http://purl.obolibrary.org/obo/GO_0061062 GO:0061063 biolink:BiologicalProcess positive regulation of nematode larval development Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go.json http://purl.obolibrary.org/obo/GO_0061063 GO:0061064 biolink:BiologicalProcess negative regulation of nematode larval development Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go.json http://purl.obolibrary.org/obo/GO_0061064 GO:0085028 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0085028 GO:0061065 biolink:BiologicalProcess regulation of dauer larval development Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. go.json http://purl.obolibrary.org/obo/GO_0061065 GO:0085029 biolink:BiologicalProcess extracellular matrix assembly The aggregation, arrangement and bonding together of the extracellular matrix. go.json http://purl.obolibrary.org/obo/GO_0085029 GO:0085026 biolink:CellularComponent tubovesicular membrane network A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains. go.json TVN|TVM network http://purl.obolibrary.org/obo/GO_0085026 GO:0061066 biolink:BiologicalProcess positive regulation of dauer larval development Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. go.json http://purl.obolibrary.org/obo/GO_0061066 GO:0061067 biolink:BiologicalProcess negative regulation of dauer larval development Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. go.json http://purl.obolibrary.org/obo/GO_0061067 GO:0085027 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0085027 GO:0061068 biolink:BiologicalProcess urethra development The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. go.json http://purl.obolibrary.org/obo/GO_0061068 GO:0085024 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by Sec complex OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Sec complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json modification by symbiont of host morphology or physiology via protein secreted by the Sec secretion system http://purl.obolibrary.org/obo/GO_0085024 GO:0061069 biolink:BiologicalProcess male urethra development The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. go.json http://purl.obolibrary.org/obo/GO_0061069 GO:0085025 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by Tat complex OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json modification by symbiont of host morphology or physiology via protein secreted by the Tat secretion system http://purl.obolibrary.org/obo/GO_0085025 GO:0085022 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085022 GO:0085023 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VII secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085023 GO:0085020 biolink:BiologicalProcess protein K6-linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair. go.json protein K6-linked polyubiquitination http://purl.obolibrary.org/obo/GO_0085020 GO:0085021 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type I secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type I secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085021 GO:0002728 biolink:BiologicalProcess negative regulation of natural killer cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production. go.json down regulation of natural killer cell cytokine production|downregulation of natural killer cell cytokine production|inhibition of natural killer cell cytokine production|negative regulation of NK cell cytokine production|down-regulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002728 GO:0002729 biolink:BiologicalProcess positive regulation of natural killer cell cytokine production Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production. go.json up-regulation of natural killer cell cytokine production|positive regulation of NK cell cytokine production|up regulation of natural killer cell cytokine production|activation of natural killer cell cytokine production|stimulation of natural killer cell cytokine production|upregulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002729 GO:0099638 biolink:BiologicalProcess endosome to plasma membrane protein transport The directed movement of proteins from the endosome to the plasma membrane in transport vesicles. go.json http://purl.obolibrary.org/obo/GO_0099638 GO:0099639 biolink:BiologicalProcess neurotransmitter receptor transport, endosome to plasma membrane The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles. go.json http://purl.obolibrary.org/obo/GO_0099639 goslim_synapse GO:0002724 biolink:BiologicalProcess regulation of T cell cytokine production Any process that modulates the frequency, rate, or extent of T cell cytokine production. go.json regulation of T-cell cytokine production|regulation of T lymphocyte cytokine production|regulation of T-lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002724 GO:0099636 biolink:BiologicalProcess cytoplasmic streaming The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains. Wikipedia:Cytoplasmic_streaming go.json http://purl.obolibrary.org/obo/GO_0099636 GO:0002725 biolink:BiologicalProcess negative regulation of T cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. go.json down regulation of T cell cytokine production|inhibition of T cell cytokine production|down-regulation of T cell cytokine production|negative regulation of T-cell cytokine production|negative regulation of T lymphocyte cytokine production|negative regulation of T-lymphocyte cytokine production|downregulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002725 GO:0099637 biolink:BiologicalProcess neurotransmitter receptor transport The directed movement of neurotransmitter receptors. go.json http://purl.obolibrary.org/obo/GO_0099637 goslim_synapse GO:0099634 biolink:CellularComponent postsynaptic specialization membrane The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. go.json http://purl.obolibrary.org/obo/GO_0099634 goslim_synapse GO:0002726 biolink:BiologicalProcess positive regulation of T cell cytokine production Any process that activates or increases the frequency, rate, or extent of T cell cytokine production. go.json upregulation of T cell cytokine production|up regulation of T cell cytokine production|stimulation of T cell cytokine production|positive regulation of T-cell cytokine production|positive regulation of T lymphocyte cytokine production|up-regulation of T cell cytokine production|activation of T cell cytokine production|positive regulation of T-lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002726 GO:0099635 biolink:MolecularActivity voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission. go.json http://purl.obolibrary.org/obo/GO_0099635 goslim_synapse GO:0002727 biolink:BiologicalProcess regulation of natural killer cell cytokine production Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production. go.json regulation of NK cell cytokine production http://purl.obolibrary.org/obo/GO_0002727 GO:0099643 biolink:BiologicalProcess signal release from synapse Any signal release from a synapse. go.json http://purl.obolibrary.org/obo/GO_0099643 goslim_synapse GO:0002731 biolink:BiologicalProcess negative regulation of dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production. go.json downregulation of dendritic cell cytokine production|down regulation of dendritic cell cytokine production|inhibition of dendritic cell cytokine production|down-regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002731 GO:0099644 biolink:BiologicalProcess protein localization to presynaptic membrane A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane. go.json protein localisation to presynaptic membrane|protein localization in presynaptic membrane|protein localisation in presynaptic membrane http://purl.obolibrary.org/obo/GO_0099644 GO:0002732 biolink:BiologicalProcess positive regulation of dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production. go.json up regulation of dendritic cell cytokine production|stimulation of dendritic cell cytokine production|up-regulation of dendritic cell cytokine production|activation of dendritic cell cytokine production|upregulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002732 GO:0002733 biolink:BiologicalProcess regulation of myeloid dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production. go.json http://purl.obolibrary.org/obo/GO_0002733 GO:0099641 biolink:BiologicalProcess anterograde axonal protein transport The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons. go.json anterograde axon cargo transport http://purl.obolibrary.org/obo/GO_0099641 goslim_synapse GO:0099642 biolink:BiologicalProcess retrograde axonal protein transport The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons. go.json retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_0099642 goslim_synapse GO:0002734 biolink:BiologicalProcess negative regulation of myeloid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production. go.json down regulation of myeloid dendritic cell cytokine production|inhibition of myeloid dendritic cell cytokine production|down-regulation of myeloid dendritic cell cytokine production|downregulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002734 GO:0099640 biolink:BiologicalProcess axo-dendritic protein transport The directed movement of proteins along microtubules in neuron projections. go.json axonal protein transport http://purl.obolibrary.org/obo/GO_0099640 goslim_synapse GO:0002730 biolink:BiologicalProcess regulation of dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production. go.json http://purl.obolibrary.org/obo/GO_0002730 GO:0061050 biolink:BiologicalProcess regulation of cell growth involved in cardiac muscle cell development Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go.json http://purl.obolibrary.org/obo/GO_0061050 GO:0085019 biolink:BiologicalProcess formation of tubovesicular network for nutrient acquisition The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json formation of a symbiont- induced tubovesicular network for nutrient acquisition from host|formation by symbiont of a tubovesicular network for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0085019 GO:0061051 biolink:BiologicalProcess positive regulation of cell growth involved in cardiac muscle cell development Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go.json http://purl.obolibrary.org/obo/GO_0061051 GO:0061052 biolink:BiologicalProcess negative regulation of cell growth involved in cardiac muscle cell development Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go.json http://purl.obolibrary.org/obo/GO_0061052 GO:0085017 biolink:BiologicalProcess entry into host cell by a symbiont-containing vacuole The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole. go.json symbiont entry into host cell forming a pathogen-containing vacuole|symbiont entry into host cell forming a parasitophorous vacuole|symbiont entry into host cell forming a symbiont-containing vacuole http://purl.obolibrary.org/obo/GO_0085017 GO:0061053 biolink:BiologicalProcess somite development The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. go.json http://purl.obolibrary.org/obo/GO_0061053 GO:0085018 biolink:BiologicalProcess maintenance of symbiont-containing vacuole by host The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment. go.json maintenance of parasitophorous vacuole|maintenance of vacuolar integrity during bacterial infection|maintenance of pathogen-containing vacuole http://purl.obolibrary.org/obo/GO_0085018 GO:0061054 biolink:BiologicalProcess dermatome development The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go.json http://purl.obolibrary.org/obo/GO_0061054 GO:0085015 biolink:BiologicalProcess dormancy maintenance of symbiont in host Any process in which a dormant state is maintained by the symbiont within the host organism. go.json NRP|non-replicating persistence http://purl.obolibrary.org/obo/GO_0085015 GO:0061055 biolink:BiologicalProcess myotome development The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. go.json http://purl.obolibrary.org/obo/GO_0061055 GO:0085016 biolink:BiologicalProcess dormancy exit of symbiont in host Exit from dormant state, also known as resuscitation, of the symbiont within the host organism. go.json resuscitation of symbiont http://purl.obolibrary.org/obo/GO_0085016 GO:0061056 biolink:BiologicalProcess sclerotome development The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. go.json http://purl.obolibrary.org/obo/GO_0061056 GO:0061057 biolink:BiologicalProcess peptidoglycan recognition protein signaling pathway A series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides. go.json Imd signalling pathway|immune deficiency signaling pathway|PGRP signaling pathway|Imd signaling pathway|immune deficiency pathway http://purl.obolibrary.org/obo/GO_0061057 GO:0085013 biolink:BiologicalProcess obsolete interaction with host via protein secreted by type VII secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type VII secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085013 GO:0061058 biolink:BiologicalProcess regulation of peptidoglycan recognition protein signaling pathway Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. go.json regulation of peptidoglycan recognition protein signalling pathway http://purl.obolibrary.org/obo/GO_0061058 GO:0085014 biolink:BiologicalProcess dormancy entry of symbiont in host Entry into a dormant state of the symbiont within the host organism. go.json http://purl.obolibrary.org/obo/GO_0085014 GO:0061059 biolink:BiologicalProcess positive regulation of peptidoglycan recognition protein signaling pathway Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. go.json positive regulation of peptidoglycan recognition protein signalling pathway http://purl.obolibrary.org/obo/GO_0061059 GO:0085011 biolink:BiologicalProcess obsolete interaction with host via protein secreted by Sec complex OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Sec complex. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json interaction with host via protein secreted by Sec secretion system http://purl.obolibrary.org/obo/GO_0085011 GO:0085012 biolink:BiologicalProcess obsolete interaction with host via protein secreted by Tat complex OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Tat complex. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json interaction with host via protein secreted by Tat secretion system http://purl.obolibrary.org/obo/GO_0085012 GO:0085010 biolink:BiologicalProcess obsolete interaction with host mediated by secreted substance entering host via endocytosis OBSOLETE. An interaction with the host organism mediated by a secreted substance from the symbiont entering host cells via endocytosis of the substance. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0085010 GO:0002739 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002739 GO:0002735 biolink:BiologicalProcess positive regulation of myeloid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production. go.json upregulation of myeloid dendritic cell cytokine production|stimulation of myeloid dendritic cell cytokine production|up regulation of myeloid dendritic cell cytokine production|activation of myeloid dendritic cell cytokine production|up-regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002735 GO:0002736 biolink:BiologicalProcess regulation of plasmacytoid dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. go.json http://purl.obolibrary.org/obo/GO_0002736 GO:0002737 biolink:BiologicalProcess negative regulation of plasmacytoid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. go.json downregulation of plasmacytoid dendritic cell cytokine production|down-regulation of plasmacytoid dendritic cell cytokine production|down regulation of plasmacytoid dendritic cell cytokine production|inhibition of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002737 GO:0099645 biolink:BiologicalProcess neurotransmitter receptor localization to postsynaptic specialization membrane A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density). go.json neurotransmitter receptor localisation in postsynaptic specialization membrane http://purl.obolibrary.org/obo/GO_0099645 goslim_synapse GO:0002738 biolink:BiologicalProcess positive regulation of plasmacytoid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. go.json up-regulation of plasmacytoid dendritic cell cytokine production|up regulation of plasmacytoid dendritic cell cytokine production|activation of plasmacytoid dendritic cell cytokine production|stimulation of plasmacytoid dendritic cell cytokine production|upregulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002738 GO:0099646 biolink:BiologicalProcess neurotransmitter receptor transport, plasma membrane to endosome Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome. go.json http://purl.obolibrary.org/obo/GO_0099646 goslim_synapse GO:0099699 biolink:CellularComponent integral component of synaptic membrane The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go.json http://purl.obolibrary.org/obo/GO_0099699 goslim_synapse GO:0002700 biolink:BiologicalProcess regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. go.json http://purl.obolibrary.org/obo/GO_0002700 GO:0002701 biolink:BiologicalProcess negative regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. go.json down-regulation of production of molecular mediator of immune response|down regulation of production of molecular mediator of immune response|inhibition of production of molecular mediator of immune response|downregulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002701 GO:0061080 biolink:BiologicalProcess right horn of sinus venosus development The progression of the right horn of the sinus venosus from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061080 GO:0061081 biolink:BiologicalProcess positive regulation of myeloid leukocyte cytokine production involved in immune response Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response. go.json positive regulation of myeloid cell cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0061081 GO:0061082 biolink:BiologicalProcess myeloid leukocyte cytokine production Any process that contributes to cytokine production by a myeloid cell. go.json http://purl.obolibrary.org/obo/GO_0061082 gocheck_do_not_annotate GO:0061083 biolink:BiologicalProcess regulation of protein refolding Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. go.json http://purl.obolibrary.org/obo/GO_0061083 GO:0061084 biolink:BiologicalProcess negative regulation of protein refolding Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. go.json http://purl.obolibrary.org/obo/GO_0061084 GO:0061085 biolink:BiologicalProcess regulation of histone H3-K27 methylation Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. go.json http://purl.obolibrary.org/obo/GO_0061085 GO:0061086 biolink:BiologicalProcess negative regulation of histone H3-K27 methylation Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. go.json http://purl.obolibrary.org/obo/GO_0061086 GO:0061087 biolink:BiologicalProcess positive regulation of histone H3-K27 methylation Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. go.json http://purl.obolibrary.org/obo/GO_0061087 GO:0061088 biolink:BiologicalProcess regulation of sequestering of zinc ion Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. go.json http://purl.obolibrary.org/obo/GO_0061088 GO:0061089 biolink:BiologicalProcess negative regulation of sequestering of zinc ion Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. go.json http://purl.obolibrary.org/obo/GO_0061089 GO:0085044 biolink:BiologicalProcess disassembly by symbiont of host cuticle The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json degradation of host cuticle|catabolism of host cuticle http://purl.obolibrary.org/obo/GO_0085044 GO:0085042 biolink:CellularComponent periarbuscular membrane A host-derived membrane surrounding the symbiont arbuscule during symbiosis. go.json http://purl.obolibrary.org/obo/GO_0085042 GO:0085040 biolink:CellularComponent obsolete extra-invasive hyphal space OBSOLETE. The space between the symbiont plasma membrane and the extra-invasive hyphal membrane. go.json http://purl.obolibrary.org/obo/GO_0085040 GO:0085041 biolink:CellularComponent arbuscule Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange. go.json http://purl.obolibrary.org/obo/GO_0085041 GO:0002706 biolink:BiologicalProcess regulation of lymphocyte mediated immunity Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. go.json http://purl.obolibrary.org/obo/GO_0002706 GO:0002707 biolink:BiologicalProcess negative regulation of lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. go.json downregulation of lymphocyte mediated immunity|down regulation of lymphocyte mediated immunity|inhibition of lymphocyte mediated immunity|down-regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002707 GO:0002708 biolink:BiologicalProcess positive regulation of lymphocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. go.json stimulation of lymphocyte mediated immunity|up regulation of lymphocyte mediated immunity|up-regulation of lymphocyte mediated immunity|activation of lymphocyte mediated immunity|upregulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002708 GO:0002709 biolink:BiologicalProcess regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell mediated immunity. go.json regulation of T-lymphocyte mediated immunity|regulation of T-cell mediated immunity|regulation of T lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002709 GO:0002702 biolink:BiologicalProcess positive regulation of production of molecular mediator of immune response Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. go.json stimulation of production of molecular mediator of immune response|upregulation of production of molecular mediator of immune response|up-regulation of production of molecular mediator of immune response|up regulation of production of molecular mediator of immune response|activation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002702 GO:0002703 biolink:BiologicalProcess regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. go.json regulation of immune cell mediated immunity|regulation of leucocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 GO:0002704 biolink:BiologicalProcess negative regulation of leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. go.json down-regulation of leukocyte mediated immunity|down regulation of leukocyte mediated immunity|downregulation of leukocyte mediated immunity|inhibition of leukocyte mediated immunity|negative regulation of immune cell mediated immunity|negative regulation of leucocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002704 GO:0002705 biolink:BiologicalProcess positive regulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. go.json upregulation of leukocyte mediated immunity|positive regulation of immune cell mediated immunity|positive regulation of leucocyte mediated immunity|up-regulation of leukocyte mediated immunity|up regulation of leukocyte mediated immunity|activation of leukocyte mediated immunity|stimulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002705 GO:0002710 biolink:BiologicalProcess negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. go.json negative regulation of T-lymphocyte mediated immunity|downregulation of T cell mediated immunity|down regulation of T cell mediated immunity|inhibition of T cell mediated immunity|down-regulation of T cell mediated immunity|negative regulation of T-cell mediated immunity|negative regulation of T lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002710 GO:0002711 biolink:BiologicalProcess positive regulation of T cell mediated immunity Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. go.json stimulation of T cell mediated immunity|up regulation of T cell mediated immunity|positive regulation of T-cell mediated immunity|positive regulation of T lymphocyte mediated immunity|up-regulation of T cell mediated immunity|activation of T cell mediated immunity|positive regulation of T-lymphocyte mediated immunity|upregulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002711 GO:0002712 biolink:BiologicalProcess regulation of B cell mediated immunity Any process that modulates the frequency, rate, or extent of B cell mediated immunity. go.json regulation of B-cell mediated immunity|regulation of B lymphocyte mediated immunity|regulation of B-lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002712 GO:0061070 biolink:BiologicalProcess female urethra development The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. go.json http://purl.obolibrary.org/obo/GO_0061070 GO:0061071 biolink:BiologicalProcess urethra epithelium development The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. go.json http://purl.obolibrary.org/obo/GO_0061071 GO:0061072 biolink:BiologicalProcess iris morphogenesis The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. go.json http://purl.obolibrary.org/obo/GO_0061072 GO:0061073 biolink:BiologicalProcess ciliary body morphogenesis The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. go.json http://purl.obolibrary.org/obo/GO_0061073 GO:0061074 biolink:BiologicalProcess regulation of neural retina development Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. go.json http://purl.obolibrary.org/obo/GO_0061074 GO:0085039 biolink:CellularComponent hyphal membrane A host-derived membrane surrounding the symbiont hypha during infection. go.json extra-invasive hyphal membrane http://purl.obolibrary.org/obo/GO_0085039 GO:0061075 biolink:BiologicalProcess positive regulation of neural retina development Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. go.json http://purl.obolibrary.org/obo/GO_0061075 GO:0061076 biolink:BiologicalProcess negative regulation of neural retina development Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. go.json http://purl.obolibrary.org/obo/GO_0061076 GO:0061077 biolink:BiologicalProcess chaperone-mediated protein folding The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone. go.json http://purl.obolibrary.org/obo/GO_0061077 GO:0085037 biolink:CellularComponent extrahaustorial membrane The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane. go.json http://purl.obolibrary.org/obo/GO_0085037 GO:0061078 biolink:BiologicalProcess positive regulation of prostaglandin secretion involved in immune response Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response. go.json positive regulation of prostaglandin secretion during immune response http://purl.obolibrary.org/obo/GO_0061078 GO:0085035 biolink:CellularComponent haustorium A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane. go.json http://purl.obolibrary.org/obo/GO_0085035 GO:0061079 biolink:BiologicalProcess left horn of sinus venosus development The progression of the left horn of the sinus venosus from its initial formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061079 GO:0085036 biolink:CellularComponent extrahaustorial matrix The space between the symbiont plasma membrane and the extrahaustorial membrane of the host. go.json http://purl.obolibrary.org/obo/GO_0085036 GO:0085033 biolink:BiologicalProcess induction by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json positive regulation by symbiont of nuclear factor kappa-light-chain-enhancer of activated B cells mediated signal transduction pathway|up regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|up-regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|stimulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|activation by symbiont of host I-kappaB kinase/NF-kappaB cascade|upregulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host NF-kappaB-mediated signal transduction pathway|positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|induction by symbiont of host I-kappaB kinase/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0085033 GO:0085034 biolink:BiologicalProcess suppression by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process that stops, prevents, or reduces the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0085034 GO:0085031 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0085031 GO:0085032 biolink:BiologicalProcess modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go.json modulation by symbiont of host NF-kappaB-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0085032 GO:0085030 biolink:BiologicalProcess symbiotic process benefiting host A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism. go.json mutualism http://purl.obolibrary.org/obo/GO_0085030 GO:0002717 biolink:BiologicalProcess positive regulation of natural killer cell mediated immunity Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity. go.json up regulation of natural killer cell mediated immunity|positive regulation of natural killer cell activity|activation of natural killer cell mediated immunity|stimulation of natural killer cell mediated immunity|upregulation of natural killer cell mediated immunity|positive regulation of NK cell activity|up-regulation of natural killer cell mediated immunity|positive regulation of NK cell mediated immunity http://purl.obolibrary.org/obo/GO_0002717 GO:0002718 biolink:BiologicalProcess regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response. go.json regulation of cytokine biosynthetic process involved in immune response|regulation of cytokine secretion involved in immune response|regulation of cytokine production during immune response http://purl.obolibrary.org/obo/GO_0002718 GO:0002719 biolink:BiologicalProcess negative regulation of cytokine production involved in immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. go.json inhibition of cytokine production during immune response|negative regulation of cytokine secretion involved in immune response|downregulation of cytokine production during immune response|down-regulation of cytokine production during immune response|negative regulation of cytokine production during immune response|negative regulation of cytokine biosynthetic process involved in immune response|down regulation of cytokine production during immune response http://purl.obolibrary.org/obo/GO_0002719 GO:0002713 biolink:BiologicalProcess negative regulation of B cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. go.json negative regulation of B-lymphocyte mediated immunity|downregulation of B cell mediated immunity|down regulation of B cell mediated immunity|inhibition of B cell mediated immunity|down-regulation of B cell mediated immunity|negative regulation of B-cell mediated immunity|negative regulation of B lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002713 GO:0002714 biolink:BiologicalProcess positive regulation of B cell mediated immunity Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. go.json positive regulation of B-cell mediated immunity|stimulation of B cell mediated immunity|positive regulation of B lymphocyte mediated immunity|up-regulation of B cell mediated immunity|activation of B cell mediated immunity|positive regulation of B-lymphocyte mediated immunity|upregulation of B cell mediated immunity|up regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002714 GO:0002715 biolink:BiologicalProcess regulation of natural killer cell mediated immunity Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity. go.json regulation of NK cell mediated immunity|regulation of natural killer cell activity http://purl.obolibrary.org/obo/GO_0002715 GO:0002716 biolink:BiologicalProcess negative regulation of natural killer cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity. go.json negative regulation of NK cell mediated immunity|negative regulation of NK cell activity|down-regulation of natural killer cell mediated immunity|down regulation of natural killer cell mediated immunity|negative regulation of natural killer cell activity|inhibition of natural killer cell mediated immunity|downregulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0002716 GO:0061090 biolink:BiologicalProcess positive regulation of sequestering of zinc ion Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. go.json http://purl.obolibrary.org/obo/GO_0061090 GO:0061091 biolink:BiologicalProcess regulation of phospholipid translocation Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go.json http://purl.obolibrary.org/obo/GO_0061091 GO:0061092 biolink:BiologicalProcess positive regulation of phospholipid translocation Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go.json http://purl.obolibrary.org/obo/GO_0061092 GO:0061093 biolink:BiologicalProcess negative regulation of phospholipid translocation Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go.json http://purl.obolibrary.org/obo/GO_0061093 GO:0061094 biolink:BiologicalProcess regulation of turning behavior involved in mating Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. go.json http://purl.obolibrary.org/obo/GO_0061094 GO:0061095 biolink:BiologicalProcess positive regulation of turning behavior involved in mating Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. go.json http://purl.obolibrary.org/obo/GO_0061095 GO:0061096 biolink:BiologicalProcess negative regulation of turning behavior involved in mating Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. go.json http://purl.obolibrary.org/obo/GO_0061096 GO:0061097 biolink:BiologicalProcess regulation of protein tyrosine kinase activity Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity. go.json http://purl.obolibrary.org/obo/GO_0061097 GO:0061098 biolink:BiologicalProcess positive regulation of protein tyrosine kinase activity Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity. go.json http://purl.obolibrary.org/obo/GO_0061098 GO:0061099 biolink:BiologicalProcess negative regulation of protein tyrosine kinase activity Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity. go.json http://purl.obolibrary.org/obo/GO_0061099 GO:0051632 biolink:BiologicalProcess negative regulation of acetylcholine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell. go.json down regulation of acetylcholine uptake|down-regulation of acetylcholine uptake|negative regulation of acetylcholine import|downregulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051632 GO:0051633 biolink:BiologicalProcess positive regulation of acetylcholine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell. go.json upregulation of acetylcholine uptake|positive regulation of acetylcholine import|stimulation of acetylcholine uptake|up regulation of acetylcholine uptake|activation of acetylcholine uptake|up-regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051633 GO:0075601 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075601 GO:0051630 biolink:BiologicalProcess acetylcholine uptake The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. go.json acetylcholine import http://purl.obolibrary.org/obo/GO_0051630 GO:0051631 biolink:BiologicalProcess regulation of acetylcholine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell. go.json regulation of acetylcholine import http://purl.obolibrary.org/obo/GO_0051631 GO:0051636 biolink:MolecularActivity obsolete Gram-negative bacterial cell surface binding OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a Gram-negative bacterial cell. go.json Gram-negative bacterial binding|Gram-negative bacterium cell surface binding|binding to Gram-negative bacterium|Gram-negative bacterium binding|Gram-negative bacterial cell surface binding http://purl.obolibrary.org/obo/GO_0051636 GO:0051637 biolink:MolecularActivity obsolete Gram-positive bacterial cell surface binding OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a Gram-positive bacterium. go.json Gram-positive bacterial binding|binding to Gram-positive bacterium|Gram-positive bacterium binding|Gram-positive bacterium cell surface binding|Gram-positive bacterial cell surface binding http://purl.obolibrary.org/obo/GO_0051637 GO:0051634 biolink:BiologicalProcess inhibition of acetylcholine uptake Any process that prevents the activation of the directed movement of acetylcholine into a cell. go.json inhibition of acetylcholine import http://purl.obolibrary.org/obo/GO_0051634 GO:0075606 biolink:BiologicalProcess transport of viral material towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane. VZ:990 go.json viral genome transport to host cell nucleus|transport of viral material to nucleus|cytoplasmic inwards viral transport http://purl.obolibrary.org/obo/GO_0075606 GO:0051635 biolink:MolecularActivity obsolete bacterial cell surface binding OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a bacterial cell. go.json binding to bacterium|bacterium binding|bacterium cell surface binding|bacterial cell surface binding|bacterial binding http://purl.obolibrary.org/obo/GO_0051635 GO:0051638 biolink:BiologicalProcess barbed-end actin filament uncapping The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. go.json barbed-end F-actin uncapping|plus end actin filament uncapping|barbed end F-actin uncapping|plus-end F-actin uncapping|plus-end actin filament uncapping|barbed end actin filament uncapping|plus end F-actin uncapping http://purl.obolibrary.org/obo/GO_0051638 GO:0051639 biolink:BiologicalProcess actin filament network formation The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments. go.json actin gel biosynthesis|actin gel formation http://purl.obolibrary.org/obo/GO_0051639 GO:1905800 biolink:BiologicalProcess negative regulation of intraciliary retrograde transport Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport. go.json down regulation of intraciliary retrograde transport|down-regulation of intraflagellar retrograde transport|negative regulation of intraflagellar retrograde transport|inhibition of intraciliary retrograde transport|downregulation of intraciliary retrograde transport|down regulation of intraflagellar retrograde transport|inhibition of intraflagellar retrograde transport|downregulation of intraflagellar retrograde transport|down-regulation of intraciliary retrograde transport http://purl.obolibrary.org/obo/GO_1905800 GO:1905801 biolink:BiologicalProcess positive regulation of intraciliary retrograde transport Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport. go.json upregulation of intraciliary retrograde transport|activation of intraflagellar retrograde transport|positive regulation of intraflagellar retrograde transport|upregulation of intraflagellar retrograde transport|up-regulation of intraciliary retrograde transport|up regulation of intraciliary retrograde transport|activation of intraciliary retrograde transport|up-regulation of intraflagellar retrograde transport|up regulation of intraflagellar retrograde transport http://purl.obolibrary.org/obo/GO_1905801 GO:1905802 biolink:BiologicalProcess regulation of cellular response to manganese ion Any process that modulates the frequency, rate or extent of cellular response to manganese ion. go.json regulation of cellular response to manganese http://purl.obolibrary.org/obo/GO_1905802 GO:1905803 biolink:BiologicalProcess negative regulation of cellular response to manganese ion Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion. go.json downregulation of cellular response to manganese ion|down regulation of cellular response to manganese ion|inhibition of cellular response to manganese ion|down-regulation of cellular response to manganese ion|downregulation of cellular response to manganese|down regulation of cellular response to manganese|inhibition of cellular response to manganese|down-regulation of cellular response to manganese|negative regulation of cellular response to manganese http://purl.obolibrary.org/obo/GO_1905803 GO:1905804 biolink:BiologicalProcess positive regulation of cellular response to manganese ion Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion. go.json up-regulation of cellular response to manganese ion|activation of cellular response to manganese ion|positive regulation of cellular response to manganese|up regulation of cellular response to manganese|upregulation of cellular response to manganese ion|up-regulation of cellular response to manganese|activation of cellular response to manganese|up regulation of cellular response to manganese ion|upregulation of cellular response to manganese http://purl.obolibrary.org/obo/GO_1905804 GO:1905805 biolink:BiologicalProcess excitatory synapse pruning The disaggregation of an excitatory synapse into its constituent components. go.json synapse clearance|synapse removal|synapse elimination|synapse disassembly http://purl.obolibrary.org/obo/GO_1905805 GO:1905806 biolink:BiologicalProcess regulation of synapse pruning Any process that modulates the frequency, rate or extent of synapse pruning. go.json regulation of synapse disassembly|regulation of synapse elimination|regulation of synapse clearance|regulation of synapse removal http://purl.obolibrary.org/obo/GO_1905806 goslim_synapse GO:1905807 biolink:BiologicalProcess negative regulation of synapse pruning Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning. go.json regulation of synapse elimination|down-regulation of synapse disassembly|regulation of synapse disassembly|down regulation of synapse disassembly|downregulation of synapse disassembly|inhibition of synapse disassembly|regulation of synapse removal|regulation of synapse clearance http://purl.obolibrary.org/obo/GO_1905807 GO:1905808 biolink:BiologicalProcess positive regulation of synapse pruning Any process that activates or increases the frequency, rate or extent of synapse pruning. go.json regulation of synapse elimination|upregulation of synapse disassembly|regulation of synapse disassembly|up-regulation of synapse disassembly|regulation of synapse clearance|regulation of synapse removal|up regulation of synapse disassembly|activation of synapse disassembly http://purl.obolibrary.org/obo/GO_1905808 GO:1905809 biolink:BiologicalProcess negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization. go.json inhibition of synapse organization and biogenesis|inhibition of synapse organisation|downregulation of synapse morphogenesis|inhibition of synapse development|downregulation of synapse organization|downregulation of synapse development|down-regulation of synapse organisation|negative regulation of synapse organisation|negative regulation of synapse organization and biogenesis|down-regulation of synapse organization and biogenesis|inhibition of synapse morphogenesis|down regulation of synapse organization|inhibition of synapse organization|down regulation of synapse organization and biogenesis|down-regulation of synapse organization|down-regulation of synapse morphogenesis|negative regulation of synapse morphogenesis|down-regulation of synapse development|negative regulation of synapse development|downregulation of synapse organisation|downregulation of synapse organization and biogenesis|down regulation of synapse morphogenesis|down regulation of synapse development|down regulation of synapse organisation http://purl.obolibrary.org/obo/GO_1905809 GO:0051643 biolink:BiologicalProcess endoplasmic reticulum localization Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell. go.json establishment and maintenance of ER localization|ER localization|endoplasmic reticulum localisation http://purl.obolibrary.org/obo/GO_0051643 GO:0051644 biolink:BiologicalProcess plastid localization Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell. go.json establishment and maintenance of plastid localization|plastid localisation http://purl.obolibrary.org/obo/GO_0051644 GO:0051641 biolink:BiologicalProcess cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. go.json intracellular localization|localization within cell|establishment and maintenance of cellular localization|establishment and maintenance of localization in cell or cell membrane|cellular localisation|single-organism cellular localization|single organism cellular localization http://purl.obolibrary.org/obo/GO_0051641 goslim_pir GO:0051642 biolink:BiologicalProcess centrosome localization Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell. go.json establishment and maintenance of centrosome localization|centrosome localisation http://purl.obolibrary.org/obo/GO_0051642 GO:0051647 biolink:BiologicalProcess nucleus localization Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. go.json nucleus localisation|cell nucleus localization|localization of nucleus|establishment and maintenance of nucleus localization http://purl.obolibrary.org/obo/GO_0051647 GO:0051648 biolink:BiologicalProcess vesicle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. go.json cytoplasmic vesicle localization|vesicle localisation|establishment and maintenance of vesicle localization http://purl.obolibrary.org/obo/GO_0051648 GO:0051645 biolink:BiologicalProcess Golgi localization Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. go.json Golgi localisation|Golgi apparatus localization|establishment and maintenance of Golgi localization|Golgi body localization http://purl.obolibrary.org/obo/GO_0051645 GO:0051646 biolink:BiologicalProcess mitochondrion localization Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell. go.json mitochondria localization|establishment and maintenance of mitochondrion localization|localization of mitochondria|mitochondrion localisation|establishment and maintenance of mitochondria localization|mitochondrial localization|localization of mitochondrion http://purl.obolibrary.org/obo/GO_0051646 GO:0051649 biolink:BiologicalProcess establishment of localization in cell Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. go.json establishment of localisation in cell|establishment of intracellular localization|positioning within cell|establishment of localization within cell|establishment of cellular localization http://purl.obolibrary.org/obo/GO_0051649 GO:1905810 biolink:BiologicalProcess regulation of excitatory synapse pruning Any process that modulates the frequency, rate or extent of excitatory synapse pruning. go.json regulation of synapse removal|regulation of synapse clearance|regulation of synapse elimination|regulation of synapse disassembly http://purl.obolibrary.org/obo/GO_1905810 GO:1905811 biolink:BiologicalProcess negative regulation of excitatory synapse pruning Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning. go.json downregulation of excitatory synapse disassembly|down regulation of excitatory synapse disassembly|regulation of synapse clearance|regulation of synapse removal|inhibition of excitatory synapse disassembly|down-regulation of excitatory synapse disassembly|regulation of synapse elimination|regulation of synapse disassembly http://purl.obolibrary.org/obo/GO_1905811 GO:1905812 biolink:BiologicalProcess regulation of motor neuron axon guidance Any process that modulates the frequency, rate or extent of motor neuron axon guidance. go.json regulation of motor axon pathfinding|regulation of motoneuron axon guidance|regulation of motor axon guidance http://purl.obolibrary.org/obo/GO_1905812 GO:1905813 biolink:BiologicalProcess negative regulation of motor neuron axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance. go.json downregulation of motor axon pathfinding|negative regulation of motor axon guidance|down-regulation of motor axon guidance|downregulation of motoneuron axon guidance|down regulation of motor axon pathfinding|down regulation of motor axon guidance|downregulation of motor neuron axon guidance|inhibition of motor axon pathfinding|negative regulation of motor axon pathfinding|inhibition of motor axon guidance|down-regulation of motor axon pathfinding|down regulation of motoneuron axon guidance|inhibition of motoneuron axon guidance|downregulation of motor axon guidance|down regulation of motor neuron axon guidance|inhibition of motor neuron axon guidance|negative regulation of motoneuron axon guidance|down-regulation of motoneuron axon guidance|down-regulation of motor neuron axon guidance http://purl.obolibrary.org/obo/GO_1905813 GO:1905814 biolink:BiologicalProcess positive regulation of motor neuron axon guidance Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance. go.json positive regulation of motoneuron axon guidance|up-regulation of motor axon pathfinding|up regulation of motoneuron axon guidance|upregulation of motor axon guidance|activation of motor axon pathfinding|up regulation of motor neuron axon guidance|up-regulation of motoneuron axon guidance|activation of motoneuron axon guidance|up-regulation of motor neuron axon guidance|activation of motor neuron axon guidance|upregulation of motor axon pathfinding|up-regulation of motor axon guidance|upregulation of motoneuron axon guidance|up regulation of motor axon guidance|positive regulation of motor axon pathfinding|upregulation of motor neuron axon guidance|positive regulation of motor axon guidance|up regulation of motor axon pathfinding|activation of motor axon guidance http://purl.obolibrary.org/obo/GO_1905814 GO:1905815 biolink:BiologicalProcess regulation of dorsal/ventral axon guidance Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance. go.json regulation of dorsoventral axon guidance|regulation of dorsal/ventral axon pathfinding|regulation of dorsal-ventral axon guidance http://purl.obolibrary.org/obo/GO_1905815 GO:1905816 biolink:BiologicalProcess negative regulation of dorsal/ventral axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance. go.json negative regulation of dorsal/ventral axon pathfinding|downregulation of dorsoventral axon guidance|down-regulation of dorsal/ventral axon pathfinding|down regulation of dorsal/ventral axon pathfinding|downregulation of dorsal-ventral axon guidance|down regulation of dorsoventral axon guidance|downregulation of dorsal/ventral axon guidance|inhibition of dorsoventral axon guidance|down regulation of dorsal-ventral axon guidance|inhibition of dorsal/ventral axon pathfinding|negative regulation of dorsoventral axon guidance|downregulation of dorsal/ventral axon pathfinding|down-regulation of dorsoventral axon guidance|down regulation of dorsal/ventral axon guidance|inhibition of dorsal-ventral axon guidance|negative regulation of dorsal-ventral axon guidance|down-regulation of dorsal-ventral axon guidance|inhibition of dorsal/ventral axon guidance|down-regulation of dorsal/ventral axon guidance http://purl.obolibrary.org/obo/GO_1905816 GO:1905817 biolink:BiologicalProcess positive regulation of dorsal/ventral axon guidance Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance. go.json up regulation of dorsal-ventral axon guidance|up-regulation of dorsoventral axon guidance|upregulation of dorsal/ventral axon pathfinding|activation of dorsoventral axon guidance|up regulation of dorsal/ventral axon guidance|up-regulation of dorsal-ventral axon guidance|activation of dorsal-ventral axon guidance|up-regulation of dorsal/ventral axon guidance|activation of dorsal/ventral axon guidance|upregulation of dorsoventral axon guidance|up-regulation of dorsal/ventral axon pathfinding|upregulation of dorsal-ventral axon guidance|up regulation of dorsal/ventral axon pathfinding|positive regulation of dorsoventral axon guidance|positive regulation of dorsal/ventral axon pathfinding|activation of dorsal/ventral axon pathfinding|upregulation of dorsal/ventral axon guidance|up regulation of dorsoventral axon guidance|positive regulation of dorsal-ventral axon guidance http://purl.obolibrary.org/obo/GO_1905817 GO:1905818 biolink:BiologicalProcess regulation of chromosome separation Any process that modulates the frequency, rate or extent of chromosome separation. go.json regulation of chromatid release|regulation of rDNA separation http://purl.obolibrary.org/obo/GO_1905818 GO:1905819 biolink:BiologicalProcess negative regulation of chromosome separation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation. go.json negative regulation of chromatid release|down-regulation of chromatid release|down regulation of chromosome separation|inhibition of rDNA separation|down regulation of chromatid release|inhibition of chromosome separation|downregulation of chromosome separation|negative regulation of rDNA separation|down-regulation of rDNA separation|downregulation of chromatid release|down regulation of rDNA separation|inhibition of chromatid release|downregulation of rDNA separation|down-regulation of chromosome separation http://purl.obolibrary.org/obo/GO_1905819 GO:0051640 biolink:BiologicalProcess organelle localization Any process in which an organelle is transported to, and/or maintained in, a specific location. go.json establishment and maintenance of organelle localization|organelle localisation http://purl.obolibrary.org/obo/GO_0051640 goslim_pir GO:0002687 biolink:BiologicalProcess positive regulation of leukocyte migration Any process that activates or increases the frequency, rate, or extent of leukocyte migration. go.json positive regulation of immune cell migration|positive regulation of leucocyte migration|up-regulation of leukocyte migration|up regulation of leukocyte migration|activation of leukocyte migration|stimulation of leukocyte migration|upregulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0002687 GO:0051654 biolink:BiologicalProcess establishment of mitochondrion localization The directed movement of the mitochondrion to a specific location. go.json establishment of mitochondrion localisation|mitochondria positioning|mitochondrial migration|establishment of mitochondria localization|mitochondrion positioning http://purl.obolibrary.org/obo/GO_0051654 GO:0051655 biolink:BiologicalProcess maintenance of vesicle location Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of vesicle localization http://purl.obolibrary.org/obo/GO_0051655 GO:0002688 biolink:BiologicalProcess regulation of leukocyte chemotaxis Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis. go.json regulation of immune cell chemotaxis|regulation of leucocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002688 GO:0002689 biolink:BiologicalProcess negative regulation of leukocyte chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis. go.json negative regulation of immune cell chemotaxis|negative regulation of leucocyte chemotaxis|downregulation of leukocyte chemotaxis|down regulation of leukocyte chemotaxis|inhibition of leukocyte chemotaxis|down-regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002689 GO:0051652 biolink:BiologicalProcess maintenance of chromosome location Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of chromosome localization http://purl.obolibrary.org/obo/GO_0051652 GO:0051653 biolink:BiologicalProcess spindle localization Any process in which is the spindle is transported to, and/or maintained in, a specific location. go.json spindle localisation|establishment and maintenance of spindle localization http://purl.obolibrary.org/obo/GO_0051653 GO:0051658 biolink:BiologicalProcess maintenance of nucleus location Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of nucleus localization|maintenance of cell nucleus location http://purl.obolibrary.org/obo/GO_0051658 GO:0002683 biolink:BiologicalProcess negative regulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. go.json down-regulation of immune system process|down regulation of immune system process|downregulation of immune system process|inhibition of immune system process http://purl.obolibrary.org/obo/GO_0002683 GO:0002684 biolink:BiologicalProcess positive regulation of immune system process Any process that activates or increases the frequency, rate, or extent of an immune system process. go.json activation of immune system process|stimulation of immune system process|upregulation of immune system process|up-regulation of immune system process|up regulation of immune system process http://purl.obolibrary.org/obo/GO_0002684 GO:0051659 biolink:BiologicalProcess maintenance of mitochondrion location Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of mitochondrion localization|maintenance of mitochondria localization http://purl.obolibrary.org/obo/GO_0051659 GO:0051656 biolink:BiologicalProcess establishment of organelle localization The directed movement of an organelle to a specific location. go.json establishment of organelle localisation http://purl.obolibrary.org/obo/GO_0051656 GO:0002685 biolink:BiologicalProcess regulation of leukocyte migration Any process that modulates the frequency, rate, or extent of leukocyte migration. go.json regulation of immune cell migration|regulation of leucocyte migration http://purl.obolibrary.org/obo/GO_0002685 GO:0002686 biolink:BiologicalProcess negative regulation of leukocyte migration Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. go.json inhibition of leukocyte migration|downregulation of leukocyte migration|negative regulation of immune cell migration|negative regulation of leucocyte migration|down-regulation of leukocyte migration|down regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0002686 GO:0051657 biolink:BiologicalProcess maintenance of organelle location Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of organelle localization http://purl.obolibrary.org/obo/GO_0051657 GO:0002680 biolink:BiologicalProcess pro-T cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell. go.json pro-T lymphocyte lineage commitment|pro-T cell fate commitment|pro-T lymphocyte fate commitment http://purl.obolibrary.org/obo/GO_0002680 GO:0002681 biolink:BiologicalProcess somatic recombination of T cell receptor gene segments The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments. go.json somatic recombination of TCR gene segments http://purl.obolibrary.org/obo/GO_0002681 GO:0002682 biolink:BiologicalProcess regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune system process. go.json http://purl.obolibrary.org/obo/GO_0002682 GO:1905820 biolink:BiologicalProcess positive regulation of chromosome separation Any process that activates or increases the frequency, rate or extent of chromosome separation. go.json upregulation of rDNA separation|activation of rDNA separation|up-regulation of chromatid release|up regulation of chromosome separation|activation of chromosome separation|up regulation of chromatid release|positive regulation of chromatid release|up-regulation of rDNA separation|upregulation of chromosome separation|up regulation of rDNA separation|upregulation of chromatid release|activation of chromatid release|positive regulation of rDNA separation|up-regulation of chromosome separation http://purl.obolibrary.org/obo/GO_1905820 GO:1905821 biolink:BiologicalProcess positive regulation of chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. go.json up regulation of eukaryotic chromosome condensation|upregulation of chromosome condensation|up-regulation of nuclear chromosome condensation|activation of eukaryotic chromosome condensation|up-regulation of eukaryotic chromosome condensation|up regulation of nuclear chromosome condensation|activation of nuclear chromosome condensation|positive regulation of nuclear chromosome condensation|up-regulation of chromosome condensation|upregulation of eukaryotic chromosome condensation|up regulation of chromosome condensation|upregulation of nuclear chromosome condensation|activation of chromosome condensation|positive regulation of eukaryotic chromosome condensation http://purl.obolibrary.org/obo/GO_1905821 GO:1905822 biolink:BiologicalProcess regulation of mitotic sister chromatid arm separation Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation. go.json http://purl.obolibrary.org/obo/GO_1905822 GO:1905823 biolink:BiologicalProcess negative regulation of mitotic sister chromatid arm separation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation. go.json down-regulation of mitotic sister chromatid arm separation|down regulation of mitotic sister chromatid arm separation|inhibition of mitotic sister chromatid arm separation|downregulation of mitotic sister chromatid arm separation http://purl.obolibrary.org/obo/GO_1905823 GO:1905824 biolink:BiologicalProcess positive regulation of mitotic sister chromatid arm separation Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation. go.json activation of mitotic sister chromatid arm separation|upregulation of mitotic sister chromatid arm separation|up-regulation of mitotic sister chromatid arm separation|up regulation of mitotic sister chromatid arm separation http://purl.obolibrary.org/obo/GO_1905824 GO:1905825 biolink:BiologicalProcess regulation of selenocysteine metabolic process Any process that modulates the frequency, rate or extent of selenocysteine metabolic process. go.json regulation of selenocysteine metabolism http://purl.obolibrary.org/obo/GO_1905825 GO:1905826 biolink:BiologicalProcess negative regulation of selenocysteine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process. go.json down regulation of selenocysteine metabolism|downregulation of selenocysteine metabolic process|downregulation of selenocysteine metabolism|inhibition of selenocysteine metabolism|down regulation of selenocysteine metabolic process|inhibition of selenocysteine metabolic process|down-regulation of selenocysteine metabolic process|down-regulation of selenocysteine metabolism|negative regulation of selenocysteine metabolism http://purl.obolibrary.org/obo/GO_1905826 GO:1905827 biolink:BiologicalProcess positive regulation of selenocysteine metabolic process Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process. go.json up regulation of selenocysteine metabolic process|up-regulation of selenocysteine metabolism|up-regulation of selenocysteine metabolic process|activation of selenocysteine metabolic process|up regulation of selenocysteine metabolism|activation of selenocysteine metabolism|positive regulation of selenocysteine metabolism|upregulation of selenocysteine metabolic process|upregulation of selenocysteine metabolism http://purl.obolibrary.org/obo/GO_1905827 GO:1905828 biolink:BiologicalProcess regulation of prostaglandin catabolic process Any process that modulates the frequency, rate or extent of prostaglandin catabolic process. go.json regulation of prostaglandin degradation|regulation of prostaglandin breakdown|regulation of prostaglandin catabolism http://purl.obolibrary.org/obo/GO_1905828 GO:1905829 biolink:BiologicalProcess negative regulation of prostaglandin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process. go.json downregulation of prostaglandin catabolic process|down regulation of prostaglandin catabolism|down-regulation of prostaglandin degradation|inhibition of prostaglandin catabolic process|negative regulation of prostaglandin degradation|inhibition of prostaglandin catabolism|down regulation of prostaglandin degradation|negative regulation of prostaglandin catabolism|down-regulation of prostaglandin catabolism|down-regulation of prostaglandin breakdown|negative regulation of prostaglandin breakdown|downregulation of prostaglandin degradation|inhibition of prostaglandin degradation|down regulation of prostaglandin breakdown|down-regulation of prostaglandin catabolic process|inhibition of prostaglandin breakdown|downregulation of prostaglandin breakdown|downregulation of prostaglandin catabolism|down regulation of prostaglandin catabolic process http://purl.obolibrary.org/obo/GO_1905829 GO:0051650 biolink:BiologicalProcess establishment of vesicle localization The directed movement of a vesicle to a specific location. go.json establishment of vesicle localisation http://purl.obolibrary.org/obo/GO_0051650 goslim_aspergillus GO:0051651 biolink:BiologicalProcess maintenance of location in cell Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. go.json maintenance of intracellular localization|intracellular sequestering|sequestering within cell|maintenance of localization within cell|cellular sequestering|cellular retention|intracellular retention|cellular storage|retention within cell|intracellular storage|maintenance of cellular localization|maintenance of localization in cell|storage within cell http://purl.obolibrary.org/obo/GO_0051651 GO:0002698 biolink:BiologicalProcess negative regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. go.json down-regulation of immune effector process|down regulation of immune effector process|inhibition of immune effector process|downregulation of immune effector process http://purl.obolibrary.org/obo/GO_0002698 GO:0051665 biolink:BiologicalProcess membrane raft localization Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. go.json membrane raft localisation|lipid raft localization|establishment and maintenance of membrane raft localization http://purl.obolibrary.org/obo/GO_0051665 GO:0002699 biolink:BiologicalProcess positive regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. go.json upregulation of immune effector process|up-regulation of immune effector process|up regulation of immune effector process|activation of immune effector process|stimulation of immune effector process http://purl.obolibrary.org/obo/GO_0002699 GO:0051666 biolink:BiologicalProcess actin cortical patch localization Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells. go.json establishment and maintenance of actin cortical patch localization|actin cortical patch localisation http://purl.obolibrary.org/obo/GO_0051666 GO:0051663 biolink:BiologicalProcess oocyte nucleus localization involved in oocyte dorsal/ventral axis specification The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte. go.json oocyte nucleus localization during oocyte axis determination|oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte axis determination, oocyte nucleus localization|oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|establishment and maintenance of oocyte nucleus localization during oocyte axis determination|oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|oocyte nucleus localization involved in oocyte dorsoventral axis specification http://purl.obolibrary.org/obo/GO_0051663 GO:0051664 biolink:BiologicalProcess nuclear pore localization Any process in which nuclear pores are transported to, or maintained in, a specific location. go.json nuclear pore distribution|establishment and maintenance of nuclear pore localization|nuclear pore localisation|positioning of nuclear pores http://purl.obolibrary.org/obo/GO_0051664 GO:0002694 biolink:BiologicalProcess regulation of leukocyte activation Any process that modulates the frequency, rate, or extent of leukocyte activation. go.json regulation of leucocyte activation|regulation of immune cell activation http://purl.obolibrary.org/obo/GO_0002694 GO:0051669 biolink:MolecularActivity fructan beta-fructosidase activity Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans. MetaCyc:3.2.1.80-RXN|EC:3.2.1.80 go.json fructanase activity|fructan b-fructosidase activity|beta-D-fructan fructohydrolase activity|exo-beta-D-fructosidase activity|polysaccharide beta-fructofuranosidase activity|fructan exohydrolase activity|exo-beta-fructosidase activity http://purl.obolibrary.org/obo/GO_0051669 GO:0002695 biolink:BiologicalProcess negative regulation of leukocyte activation Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. go.json down regulation of leukocyte activation|inhibition of leukocyte activation|down-regulation of leukocyte activation|negative regulation of leucocyte activation|negative regulation of immune cell activation|downregulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0002695 GO:0051667 biolink:BiologicalProcess establishment of plastid localization The directed movement of a plastid to a specific location in the cell. go.json establishment of plastid localisation http://purl.obolibrary.org/obo/GO_0051667 GO:0002696 biolink:BiologicalProcess positive regulation of leukocyte activation Any process that activates or increases the frequency, rate, or extent of leukocyte activation. go.json positive regulation of immune cell activation|positive regulation of leucocyte activation|upregulation of leukocyte activation|up regulation of leukocyte activation|stimulation of leukocyte activation|up-regulation of leukocyte activation|activation of leukocyte activation http://purl.obolibrary.org/obo/GO_0002696 GO:0051668 biolink:BiologicalProcess localization within membrane Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. go.json positioning within membrane|localisation within membrane|localization to membrane|establishment and maintenance of localization in membrane|establishment and maintenance of position in membrane http://purl.obolibrary.org/obo/GO_0051668 GO:0002697 biolink:BiologicalProcess regulation of immune effector process Any process that modulates the frequency, rate, or extent of an immune effector process. go.json http://purl.obolibrary.org/obo/GO_0002697 GO:0002690 biolink:BiologicalProcess positive regulation of leukocyte chemotaxis Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis. go.json positive regulation of leucocyte chemotaxis|positive regulation of immune cell chemotaxis|upregulation of leukocyte chemotaxis|up regulation of leukocyte chemotaxis|stimulation of leukocyte chemotaxis|up-regulation of leukocyte chemotaxis|activation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002690 GO:0002691 biolink:BiologicalProcess regulation of cellular extravasation Any process that modulates the frequency, rate, or extent of cellular extravasation. go.json http://purl.obolibrary.org/obo/GO_0002691 GO:0002692 biolink:BiologicalProcess negative regulation of cellular extravasation Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation. go.json downregulation of cellular extravasation|down regulation of cellular extravasation|inhibition of cellular extravasation|down-regulation of cellular extravasation http://purl.obolibrary.org/obo/GO_0002692 GO:0002693 biolink:BiologicalProcess positive regulation of cellular extravasation Any process that activates or increases the frequency, rate, or extent of cellular extravasation. go.json up regulation of cellular extravasation|stimulation of cellular extravasation|up-regulation of cellular extravasation|activation of cellular extravasation|upregulation of cellular extravasation http://purl.obolibrary.org/obo/GO_0002693 GO:1905830 biolink:BiologicalProcess positive regulation of prostaglandin catabolic process Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process. go.json positive regulation of prostaglandin catabolism|up-regulation of prostaglandin degradation|up regulation of prostaglandin catabolism|upregulation of prostaglandin catabolic process|up regulation of prostaglandin degradation|positive regulation of prostaglandin degradation|activation of prostaglandin degradation|up-regulation of prostaglandin catabolism|up-regulation of prostaglandin breakdown|activation of prostaglandin catabolism|up regulation of prostaglandin breakdown|up-regulation of prostaglandin catabolic process|upregulation of prostaglandin degradation|activation of prostaglandin breakdown|positive regulation of prostaglandin breakdown|up regulation of prostaglandin catabolic process|upregulation of prostaglandin catabolism|upregulation of prostaglandin breakdown|activation of prostaglandin catabolic process http://purl.obolibrary.org/obo/GO_1905830 GO:1905831 biolink:BiologicalProcess negative regulation of spindle assembly Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly. go.json downregulation of spindle formation|downregulation of spindle biosynthesis|negative regulation of bipolar spindle formation|down-regulation of bipolar spindle formation|down regulation of spindle biosynthesis|down regulation of bipolar spindle formation|inhibition of spindle biosynthesis|downregulation of spindle assembly|down-regulation of spindle biosynthesis|negative regulation of spindle biosynthesis|downregulation of bipolar spindle biosynthesis|inhibition of bipolar spindle formation|down-regulation of spindle formation|downregulation of bipolar spindle formation|negative regulation of spindle formation|down regulation of spindle assembly|down regulation of spindle formation|down regulation of bipolar spindle biosynthesis|inhibition of spindle assembly|inhibition of bipolar spindle biosynthesis|down-regulation of spindle assembly|negative regulation of bipolar spindle biosynthesis|inhibition of spindle formation|down-regulation of bipolar spindle biosynthesis http://purl.obolibrary.org/obo/GO_1905831 GO:1905832 biolink:BiologicalProcess positive regulation of spindle assembly Any process that activates or increases the frequency, rate or extent of spindle assembly. go.json up-regulation of spindle formation|up-regulation of spindle biosynthesis|activation of spindle biosynthesis|upregulation of bipolar spindle formation|up regulation of spindle formation|positive regulation of bipolar spindle biosynthesis|up regulation of spindle assembly|up regulation of bipolar spindle biosynthesis|activation of spindle formation|positive regulation of spindle formation|up-regulation of spindle assembly|upregulation of spindle biosynthesis|activation of spindle assembly|up-regulation of bipolar spindle biosynthesis|up-regulation of bipolar spindle formation|activation of bipolar spindle biosynthesis|upregulation of spindle formation|up regulation of bipolar spindle formation|positive regulation of spindle biosynthesis|upregulation of spindle assembly|up regulation of spindle biosynthesis|activation of bipolar spindle formation|positive regulation of bipolar spindle formation|upregulation of bipolar spindle biosynthesis http://purl.obolibrary.org/obo/GO_1905832 GO:1905833 biolink:BiologicalProcess negative regulation of microtubule nucleation Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. go.json downregulation of microtubule nucleation|down regulation of microtubule nucleation|inhibition of microtubule nucleation|down-regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_1905833 GO:1905834 biolink:BiologicalProcess response to pyrimidine ribonucleotide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus. go.json http://purl.obolibrary.org/obo/GO_1905834 GO:1905835 biolink:BiologicalProcess cellular response to pyrimidine ribonucleotide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus. go.json http://purl.obolibrary.org/obo/GO_1905835 GO:1905836 biolink:BiologicalProcess response to triterpenoid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus. go.json http://purl.obolibrary.org/obo/GO_1905836 GO:1905837 biolink:BiologicalProcess cellular response to triterpenoid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus. go.json http://purl.obolibrary.org/obo/GO_1905837 GO:1905838 biolink:BiologicalProcess regulation of telomeric D-loop disassembly Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly. go.json http://purl.obolibrary.org/obo/GO_1905838 GO:1905839 biolink:BiologicalProcess negative regulation of telomeric D-loop disassembly Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly. go.json downregulation of telomeric D-loop disassembly|down regulation of telomeric D-loop disassembly|inhibition of telomeric D-loop disassembly|down-regulation of telomeric D-loop disassembly http://purl.obolibrary.org/obo/GO_1905839 GO:0051661 biolink:BiologicalProcess maintenance of centrosome location Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of centrosome localization http://purl.obolibrary.org/obo/GO_0051661 GO:0051662 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051662 GO:0051660 biolink:BiologicalProcess establishment of centrosome localization The directed movement of the centrosome to a specific location. go.json establishment of centrosome localisation|centrosome positioning http://purl.obolibrary.org/obo/GO_0051660 GO:0002665 biolink:BiologicalProcess negative regulation of T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction. go.json negative regulation of T lymphocyte tolerance induction|negative regulation of T-lymphocyte tolerance induction|downregulation of T cell tolerance induction|down regulation of T cell tolerance induction|inhibition of T cell tolerance induction|down-regulation of T cell tolerance induction|negative regulation of T-cell tolerance induction http://purl.obolibrary.org/obo/GO_0002665 GO:0099610 biolink:BiologicalProcess action potential initiation The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate. go.json action potential firing|action potential triggering http://purl.obolibrary.org/obo/GO_0099610 GO:0051676 biolink:BiologicalProcess pullulan metabolic process The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. go.json pullulan metabolism http://purl.obolibrary.org/obo/GO_0051676 GO:0002666 biolink:BiologicalProcess positive regulation of T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction. go.json stimulation of T cell tolerance induction|up regulation of T cell tolerance induction|positive regulation of T-cell tolerance induction|positive regulation of T lymphocyte tolerance induction|activation of T cell tolerance induction|up-regulation of T cell tolerance induction|positive regulation of T-lymphocyte tolerance induction|upregulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002666 GO:0051677 biolink:BiologicalProcess pullulan biosynthetic process The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. go.json http://purl.obolibrary.org/obo/GO_0051677 GO:0099611 biolink:BiologicalProcess regulation of action potential firing threshold Any process that regulates the potential at which an axon potential is triggered. go.json http://purl.obolibrary.org/obo/GO_0099611 GO:0051674 biolink:BiologicalProcess localization of cell Any process in which a cell is transported to, and/or maintained in, a specific location. go.json establishment and maintenance of localization of cell|establishment and maintenance of cell localization|localisation of cell|cell localization http://purl.obolibrary.org/obo/GO_0051674 GO:0002667 biolink:BiologicalProcess regulation of T cell anergy Any process that modulates the frequency, rate, or extent of T cell anergy. go.json regulation of T-lymphocyte anergy|regulation of T lymphocyte anergy|regulation of T-cell anergy http://purl.obolibrary.org/obo/GO_0002667 GO:0002668 biolink:BiologicalProcess negative regulation of T cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy. go.json negative regulation of T-lymphocyte anergy|negative regulation of T lymphocyte anergy|negative regulation of T-cell anergy|down-regulation of T cell anergy|down regulation of T cell anergy|inhibition of T cell anergy|downregulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002668 GO:0051675 biolink:MolecularActivity isopullulanase activity Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose). EC:3.2.1.57|MetaCyc:3.2.1.57-RXN go.json pullulan 4-glucanohydrolase (isopanose-forming) activity http://purl.obolibrary.org/obo/GO_0051675 GO:0002661 biolink:BiologicalProcess regulation of B cell tolerance induction Any process that modulates the frequency, rate, or extent of B cell tolerance induction. go.json regulation of B-cell tolerance induction|regulation of B lymphocyte tolerance induction|regulation of B-lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002661 GO:0002662 biolink:BiologicalProcess negative regulation of B cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction. go.json negative regulation of B-lymphocyte tolerance induction|downregulation of B cell tolerance induction|down regulation of B cell tolerance induction|inhibition of B cell tolerance induction|down-regulation of B cell tolerance induction|negative regulation of B-cell tolerance induction|negative regulation of B lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002662 GO:0002663 biolink:BiologicalProcess positive regulation of B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction. go.json positive regulation of B-cell tolerance induction|stimulation of B cell tolerance induction|positive regulation of B lymphocyte tolerance induction|up-regulation of B cell tolerance induction|activation of B cell tolerance induction|positive regulation of B-lymphocyte tolerance induction|upregulation of B cell tolerance induction|up regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002663 GO:0051678 biolink:BiologicalProcess pullulan catabolic process The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. go.json http://purl.obolibrary.org/obo/GO_0051678 GO:0051679 biolink:BiologicalProcess 6-alpha-maltosylglucose metabolic process The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose. go.json 6-alpha-maltosylglucose metabolism|isopanose metabolism|isopanose metabolic process http://purl.obolibrary.org/obo/GO_0051679 GO:0002664 biolink:BiologicalProcess regulation of T cell tolerance induction Any process that modulates the frequency, rate, or extent of T cell tolerance induction. go.json regulation of T-cell tolerance induction|regulation of T lymphocyte tolerance induction|regulation of T-lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002664 GO:0002660 biolink:BiologicalProcess positive regulation of peripheral tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction. go.json stimulation of peripheral tolerance induction|up regulation of peripheral tolerance induction|activation of peripheral tolerance induction|up-regulation of peripheral tolerance induction|upregulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002660 GO:0061000 biolink:BiologicalProcess negative regulation of dendritic spine development Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061000 GO:0061001 biolink:BiologicalProcess regulation of dendritic spine morphogenesis Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go.json http://purl.obolibrary.org/obo/GO_0061001 GO:1905850 biolink:BiologicalProcess positive regulation of forward locomotion Any process that activates or increases the frequency, rate or extent of forward locomotion. go.json upregulation of forward locomotion|up regulation of forward locomotion|up-regulation of forward locomotion|activation of forward locomotion http://purl.obolibrary.org/obo/GO_1905850 GO:0061002 biolink:BiologicalProcess negative regulation of dendritic spine morphogenesis Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go.json http://purl.obolibrary.org/obo/GO_0061002 GO:1905840 biolink:BiologicalProcess positive regulation of telomeric D-loop disassembly Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly. go.json upregulation of telomeric D-loop disassembly|up regulation of telomeric D-loop disassembly|up-regulation of telomeric D-loop disassembly|activation of telomeric D-loop disassembly http://purl.obolibrary.org/obo/GO_1905840 GO:1905841 biolink:BiologicalProcess response to oxidopamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus. go.json http://purl.obolibrary.org/obo/GO_1905841 GO:0061003 biolink:BiologicalProcess positive regulation of dendritic spine morphogenesis Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go.json http://purl.obolibrary.org/obo/GO_0061003 GO:1905842 biolink:BiologicalProcess cellular response to oxidopamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus. go.json http://purl.obolibrary.org/obo/GO_1905842 GO:0061004 biolink:BiologicalProcess pattern specification involved in kidney development Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate. go.json pattern formation involved in kidney development|kidney pattern specification|kidney pattern formation http://purl.obolibrary.org/obo/GO_0061004 GO:1905843 biolink:BiologicalProcess regulation of cellular response to gamma radiation Any process that modulates the frequency, rate or extent of cellular response to gamma radiation. go.json regulation of cellular response to gamma ray|regulation of cellular response to gamma-ray photon http://purl.obolibrary.org/obo/GO_1905843 GO:0061005 biolink:BiologicalProcess cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061005 GO:1905844 biolink:BiologicalProcess negative regulation of cellular response to gamma radiation Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation. go.json downregulation of cellular response to gamma ray|inhibition of cellular response to gamma-ray photon|down regulation of cellular response to gamma ray|down-regulation of cellular response to gamma-ray photon|negative regulation of cellular response to gamma-ray photon|downregulation of cellular response to gamma radiation|down regulation of cellular response to gamma-ray photon|down-regulation of cellular response to gamma ray|negative regulation of cellular response to gamma ray|down regulation of cellular response to gamma radiation|inhibition of cellular response to gamma radiation|down-regulation of cellular response to gamma radiation|downregulation of cellular response to gamma-ray photon|inhibition of cellular response to gamma ray http://purl.obolibrary.org/obo/GO_1905844 GO:0061006 biolink:BiologicalProcess regulation of cell proliferation involved in kidney morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. go.json http://purl.obolibrary.org/obo/GO_0061006 GO:1905845 biolink:BiologicalProcess positive regulation of cellular response to gamma radiation Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation. go.json up regulation of cellular response to gamma-ray photon|up-regulation of cellular response to gamma ray|positive regulation of cellular response to gamma-ray photon|up regulation of cellular response to gamma radiation|activation of cellular response to gamma radiation|up-regulation of cellular response to gamma radiation|upregulation of cellular response to gamma-ray photon|activation of cellular response to gamma-ray photon|activation of cellular response to gamma ray|upregulation of cellular response to gamma ray|positive regulation of cellular response to gamma ray|upregulation of cellular response to gamma radiation|up-regulation of cellular response to gamma-ray photon|up regulation of cellular response to gamma ray http://purl.obolibrary.org/obo/GO_1905845 GO:0061007 biolink:BiologicalProcess hepaticobiliary system process An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. go.json hepatobiliary system process http://purl.obolibrary.org/obo/GO_0061007 GO:0061008 biolink:BiologicalProcess hepaticobiliary system development The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. go.json hepatobiliary system development http://purl.obolibrary.org/obo/GO_0061008 GO:1905846 biolink:BiologicalProcess regulation of cellular response to oxidopamine Any process that modulates the frequency, rate or extent of cellular response to oxidopamine. go.json http://purl.obolibrary.org/obo/GO_1905846 GO:1905847 biolink:BiologicalProcess negative regulation of cellular response to oxidopamine Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine. go.json downregulation of cellular response to oxidopamine|down regulation of cellular response to oxidopamine|inhibition of cellular response to oxidopamine|down-regulation of cellular response to oxidopamine http://purl.obolibrary.org/obo/GO_1905847 GO:0061009 biolink:BiologicalProcess common bile duct development The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine. go.json extrahepatic bile duct development|CBD development|bile duct development|EHBD development http://purl.obolibrary.org/obo/GO_0061009 GO:1905848 biolink:BiologicalProcess positive regulation of cellular response to oxidopamine Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine. go.json up-regulation of cellular response to oxidopamine|activation of cellular response to oxidopamine|upregulation of cellular response to oxidopamine|up regulation of cellular response to oxidopamine http://purl.obolibrary.org/obo/GO_1905848 GO:0099618 biolink:MolecularActivity UDP-glucuronic acid dehydrogenase activity Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+. EC:1.1.1.305|RHEA:24702 go.json UDP-GlcUA decarboxylase activity http://purl.obolibrary.org/obo/GO_0099618 GO:1905849 biolink:BiologicalProcess negative regulation of forward locomotion Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion. go.json downregulation of forward locomotion|down regulation of forward locomotion|inhibition of forward locomotion|down-regulation of forward locomotion http://purl.obolibrary.org/obo/GO_1905849 GO:0099619 biolink:MolecularActivity UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. EC:2.1.2.13|RHEA:24706 go.json UDP-L-Ara4N formyltransferase activity|10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity|ArnAFT activity http://purl.obolibrary.org/obo/GO_0099619 GO:0099616 biolink:CellularComponent extrinsic component of matrix side of mitochondrial inner membrane The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go.json http://purl.obolibrary.org/obo/GO_0099616 GO:0099617 biolink:CellularComponent matrix side of mitochondrial inner membrane The side (leaflet) of the mitochondrial inner membrane that faces the matrix. go.json http://purl.obolibrary.org/obo/GO_0099617 GO:0002669 biolink:BiologicalProcess positive regulation of T cell anergy Any process that activates or increases the frequency, rate, or extent of T cell anergy. go.json positive regulation of T lymphocyte anergy|positive regulation of T-cell anergy|up regulation of T cell anergy|activation of T cell anergy|stimulation of T cell anergy|upregulation of T cell anergy|positive regulation of T-lymphocyte anergy|up-regulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002669 GO:0051672 biolink:BiologicalProcess catabolism by organism of cell wall peptidoglycan in other organism The chemical reactions and pathways resulting in the breakdown of the cell wall peptidoglycans of another organism. go.json cell wall catabolism in other organism|catabolism of cell wall peptidoglycans of other organism|cell wall catabolic process in other organism|cell wall peptidoglycan catabolic process in another organism|catabolic process of cell wall peptidoglycans of other organism http://purl.obolibrary.org/obo/GO_0051672 GO:0099614 biolink:BiologicalProcess protein localization to spore cell wall A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall. go.json protein targeting to spore cell wall http://purl.obolibrary.org/obo/GO_0099614 GO:0099615 biolink:MolecularActivity (D)-2-hydroxyglutarate-pyruvate transhydrogenase activity Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor. go.json D-2HG-pyruvate transhydrogenase activity|R-2-hydroxyglutarate alpha-pyruvate transhydrogenase activity http://purl.obolibrary.org/obo/GO_0099615 GO:0051673 biolink:BiologicalProcess membrane disruption in other organism The disruption of the membranes of another organism, leading to damage to its cells and possibly death of that organism. go.json membrane disruption in another organism|cytolysis, by membrane disruption, in other organism http://purl.obolibrary.org/obo/GO_0051673 GO:0099612 biolink:BiologicalProcess protein localization to axon A process in which a protein is transported to or maintained in a location within an axon. go.json http://purl.obolibrary.org/obo/GO_0099612 GO:0051670 biolink:MolecularActivity inulinase activity Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin. MetaCyc:3.2.1.7-RXN|EC:3.2.1.7 go.json indoinulinase activity|exoinulinase activity|2,1-beta-D-fructan fructanohydrolase activity|inulase activity|endo-inulinase activity http://purl.obolibrary.org/obo/GO_0051670 GO:0051671 biolink:BiologicalProcess induction of autolysin activity in other organism Any process in which an organism initiates the activity of the inactive enzyme autolysin in another organism. The autolysin enzyme belongs to, and is active in, the other organism. go.json activation of autolytic activity in other organism|positive regulation of autolysin activity in another organism|activation of autolysin activity in another organism|induction of autolytic activity in other organism|induction of autolysis in other organism|induction of autolysin activity in another organism|activation of autolysis in other organism http://purl.obolibrary.org/obo/GO_0051671 GO:0099613 biolink:BiologicalProcess protein localization to cell wall The process of directing proteins towards the cell-wall. go.json http://purl.obolibrary.org/obo/GO_0099613 GO:0099621 biolink:MolecularActivity undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate. EC:2.4.2.53|RHEA:27722|MetaCyc:RXN0-3521 go.json undecaprenyl-phosphate Ara4FN transferase activity|undecaprenyl phosphate-L-Ara4FN transferase activity|Ara4FN transferase activity http://purl.obolibrary.org/obo/GO_0099621 GO:0002676 biolink:BiologicalProcess regulation of chronic inflammatory response Any process that modulates the frequency, rate, or extent of a chronic inflammatory response. go.json http://purl.obolibrary.org/obo/GO_0002676 GO:0051687 biolink:BiologicalProcess maintenance of spindle location Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of spindle localization http://purl.obolibrary.org/obo/GO_0051687 GO:0002677 biolink:BiologicalProcess negative regulation of chronic inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response. go.json inhibition of chronic inflammatory response|downregulation of chronic inflammatory response|down-regulation of chronic inflammatory response|down regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0002677 GO:0099622 biolink:BiologicalProcess cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. go.json http://purl.obolibrary.org/obo/GO_0099622 GO:0051688 biolink:BiologicalProcess maintenance of plastid location Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of plastid localization http://purl.obolibrary.org/obo/GO_0051688 GO:0002678 biolink:BiologicalProcess positive regulation of chronic inflammatory response Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response. go.json up-regulation of chronic inflammatory response|up regulation of chronic inflammatory response|activation of chronic inflammatory response|stimulation of chronic inflammatory response|upregulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0002678 GO:0051685 biolink:BiologicalProcess maintenance of ER location Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of ER localization|maintenance of endoplasmic reticulum localization http://purl.obolibrary.org/obo/GO_0051685 GO:0051686 biolink:BiologicalProcess establishment of ER localization The directed movement of the endoplasmic reticulum to a specific location. go.json establishment of ER localisation|establishment of endoplasmic reticulum localization http://purl.obolibrary.org/obo/GO_0051686 GO:0099620 biolink:MolecularActivity UDP-4-amino-4-deoxy-L-arabinose aminotransferase Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate. EC:2.6.1.87|RHEA:24710 go.json UDP-L-Ara4N transaminase|UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase|UDP-Ara4O aminotransferase|UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase|UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase http://purl.obolibrary.org/obo/GO_0099620 GO:0002679 biolink:BiologicalProcess respiratory burst involved in defense response A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go.json http://purl.obolibrary.org/obo/GO_0002679 GO:0002672 biolink:BiologicalProcess positive regulation of B cell anergy Any process that activates or increases the frequency, rate, or extent of B cell anergy. go.json activation of B cell anergy|stimulation of B cell anergy|upregulation of B cell anergy|positive regulation of B-lymphocyte anergy|up-regulation of B cell anergy|positive regulation of B lymphocyte anergy|positive regulation of B-cell anergy|up regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002672 GO:0002673 biolink:BiologicalProcess regulation of acute inflammatory response Any process that modulates the frequency, rate, or extent of an acute inflammatory response. go.json http://purl.obolibrary.org/obo/GO_0002673 GO:0002674 biolink:BiologicalProcess negative regulation of acute inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response. go.json inhibition of acute inflammatory response|downregulation of acute inflammatory response|down-regulation of acute inflammatory response|down regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0002674 GO:0051689 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051689 GO:0002675 biolink:BiologicalProcess positive regulation of acute inflammatory response Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response. go.json up-regulation of acute inflammatory response|up regulation of acute inflammatory response|activation of acute inflammatory response|stimulation of acute inflammatory response|upregulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0002675 GO:0002670 biolink:BiologicalProcess regulation of B cell anergy Any process that modulates the frequency, rate, or extent of B cell anergy. go.json regulation of B-lymphocyte anergy|regulation of B lymphocyte anergy|regulation of B-cell anergy http://purl.obolibrary.org/obo/GO_0002670 GO:0002671 biolink:BiologicalProcess negative regulation of B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy. go.json negative regulation of B lymphocyte anergy|negative regulation of B-cell anergy|down-regulation of B cell anergy|down regulation of B cell anergy|inhibition of B cell anergy|downregulation of B cell anergy|negative regulation of B-lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002671 GO:1905860 biolink:BiologicalProcess positive regulation of heparan sulfate proteoglycan binding Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding. go.json up-regulation of heparan sulfate proteoglycan binding|activation of heparan sulfate proteoglycan binding|positive regulation of heparin proteoglycan binding|up regulation of heparin proteoglycan binding|upregulation of heparan sulfate proteoglycan binding|up-regulation of heparin proteoglycan binding|up regulation of heparan sulfate proteoglycan binding|activation of heparin proteoglycan binding|upregulation of heparin proteoglycan binding http://purl.obolibrary.org/obo/GO_1905860 GO:1905861 biolink:BiologicalProcess intranuclear rod assembly The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod. go.json intranuclear rod formation|intranuclear actin rod assembly|intranuclear actin rod formation http://purl.obolibrary.org/obo/GO_1905861 GO:1905851 biolink:BiologicalProcess negative regulation of backward locomotion Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion. go.json down regulation of backward locomotion|inhibition of backward locomotion|downregulation of backward locomotion|down-regulation of backward locomotion http://purl.obolibrary.org/obo/GO_1905851 GO:1905852 biolink:BiologicalProcess positive regulation of backward locomotion Any process that activates or increases the frequency, rate or extent of backward locomotion. go.json upregulation of backward locomotion|up-regulation of backward locomotion|up regulation of backward locomotion|activation of backward locomotion http://purl.obolibrary.org/obo/GO_1905852 GO:1905853 biolink:BiologicalProcess regulation of heparan sulfate binding Any process that modulates the frequency, rate or extent of heparan sulfate binding. go.json http://purl.obolibrary.org/obo/GO_1905853 GO:1905854 biolink:BiologicalProcess negative regulation of heparan sulfate binding Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding. go.json down-regulation of heparan sulfate binding|down regulation of heparan sulfate binding|downregulation of heparan sulfate binding|inhibition of heparan sulfate binding http://purl.obolibrary.org/obo/GO_1905854 GO:1905855 biolink:BiologicalProcess positive regulation of heparan sulfate binding Any process that activates or increases the frequency, rate or extent of heparan sulfate binding. go.json up regulation of heparan sulfate binding|activation of heparan sulfate binding|upregulation of heparan sulfate binding|up-regulation of heparan sulfate binding http://purl.obolibrary.org/obo/GO_1905855 GO:1905856 biolink:BiologicalProcess negative regulation of pentose-phosphate shunt Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt. go.json http://purl.obolibrary.org/obo/GO_1905856 GO:1905857 biolink:BiologicalProcess positive regulation of pentose-phosphate shunt Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt. go.json http://purl.obolibrary.org/obo/GO_1905857 GO:1905858 biolink:BiologicalProcess regulation of heparan sulfate proteoglycan binding Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding. go.json regulation of heparin proteoglycan binding http://purl.obolibrary.org/obo/GO_1905858 GO:1905859 biolink:BiologicalProcess negative regulation of heparan sulfate proteoglycan binding Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding. go.json down regulation of heparin proteoglycan binding|negative regulation of heparin proteoglycan binding|down-regulation of heparin proteoglycan binding|downregulation of heparan sulfate proteoglycan binding|inhibition of heparin proteoglycan binding|down regulation of heparan sulfate proteoglycan binding|inhibition of heparan sulfate proteoglycan binding|down-regulation of heparan sulfate proteoglycan binding|downregulation of heparin proteoglycan binding http://purl.obolibrary.org/obo/GO_1905859 GO:0099629 biolink:CellularComponent postsynaptic specialization of symmetric synapse A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses. go.json postsynaptic density of inhibitory synapse http://purl.obolibrary.org/obo/GO_0099629 goslim_synapse GO:0051680 biolink:BiologicalProcess 6-alpha-maltosylglucose biosynthetic process The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose. go.json isopanose biosynthetic process|isopanose biosynthesis http://purl.obolibrary.org/obo/GO_0051680 GO:0099627 biolink:BiologicalProcess neurotransmitter receptor cycle The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping). go.json http://purl.obolibrary.org/obo/GO_0099627 GO:0099628 biolink:BiologicalProcess neurotransmitter receptor diffusion trapping The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane. go.json http://purl.obolibrary.org/obo/GO_0099628 goslim_synapse GO:0099625 biolink:BiologicalProcess ventricular cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. go.json http://purl.obolibrary.org/obo/GO_0099625 GO:0051683 biolink:BiologicalProcess establishment of Golgi localization The directed movement of the Golgi to a specific location. go.json establishment of Golgi apparatus localization|establishment of Golgi body localization|establishment of Golgi localisation http://purl.obolibrary.org/obo/GO_0051683 GO:0051684 biolink:BiologicalProcess maintenance of Golgi location Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere. go.json maintenance of Golgi body localization|maintenance of Golgi apparatus localization|maintenance of Golgi localization http://purl.obolibrary.org/obo/GO_0051684 GO:0099626 biolink:MolecularActivity voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels. go.json voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099626 goslim_synapse GO:0051681 biolink:BiologicalProcess 6-alpha-maltosylglucose catabolic process The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose. go.json isopanose catabolism|isopanose catabolic process http://purl.obolibrary.org/obo/GO_0051681 GO:0099623 biolink:BiologicalProcess regulation of cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte. go.json regulation of cardiac muscle cell repolarization|heart repolarization|regulation of cardiomyocyte membrane repolarization http://purl.obolibrary.org/obo/GO_0099623 GO:0051682 biolink:BiologicalProcess galactomannan catabolic process The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units. go.json http://purl.obolibrary.org/obo/GO_0051682 GO:0099624 biolink:BiologicalProcess atrial cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. go.json http://purl.obolibrary.org/obo/GO_0099624 GO:0002643 biolink:BiologicalProcess regulation of tolerance induction Any process that modulates the frequency, rate, or extent of tolerance induction. go.json http://purl.obolibrary.org/obo/GO_0002643 GO:0051698 biolink:MolecularActivity saccharopine oxidase activity Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2. go.json SAX activity http://purl.obolibrary.org/obo/GO_0051698 GO:0002644 biolink:BiologicalProcess negative regulation of tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction. go.json inhibition of tolerance induction|downregulation of tolerance induction|down-regulation of tolerance induction|down regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0002644 GO:0051699 biolink:MolecularActivity proline oxidase activity Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2. MetaCyc:RXN-821|RHEA:26124 go.json http://purl.obolibrary.org/obo/GO_0051699 GO:0051696 biolink:BiologicalProcess pointed-end actin filament uncapping The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. go.json pointed end actin filament uncapping|minus end actin filament uncapping|minus-end actin filament uncapping|minus-end F-actin uncapping|pointed-end F-actin uncapping|minus end F-actin uncapping|pointed end F-actin uncapping http://purl.obolibrary.org/obo/GO_0051696 GO:0002645 biolink:BiologicalProcess positive regulation of tolerance induction Any process that activates or increases the frequency, rate, or extent of tolerance induction. go.json up-regulation of tolerance induction|up regulation of tolerance induction|activation of tolerance induction|stimulation of tolerance induction|upregulation of tolerance induction http://purl.obolibrary.org/obo/GO_0002645 GO:0051697 biolink:BiologicalProcess protein delipidation The breakage of covalent bonds to detach lipid groups from a protein. go.json http://purl.obolibrary.org/obo/GO_0051697 GO:0002646 biolink:BiologicalProcess regulation of central tolerance induction Any process that modulates the frequency, rate, or extent of central tolerance induction. go.json http://purl.obolibrary.org/obo/GO_0002646 GO:0002640 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002640 GO:0002641 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002641 GO:0002642 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002642 GO:0061020 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061020 GO:1905870 biolink:BiologicalProcess positive regulation of 3'-UTR-mediated mRNA stabilization Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. go.json up regulation of 3'-untranslated region-mediated mRNA stabilization|up regulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-UTR-mediated mRNA stabilization|upregulation of 3'-untranslated region-mediated mRNA stabilization|upregulation of 3'-UTR-mediated mRNA stabilization|positive regulation of 3'-untranslated region-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_1905870 GO:0061021 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061021 GO:1905871 biolink:BiologicalProcess regulation of protein localization to cell leading edge Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. go.json regulation of protein localisation in cell leading edge|regulation of protein localization in cell leading edge|regulation of protein localisation to cell leading edge http://purl.obolibrary.org/obo/GO_1905871 GO:0061022 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061022 GO:1905872 biolink:BiologicalProcess negative regulation of protein localization to cell leading edge Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. go.json inhibition of protein localization in cell leading edge|down-regulation of protein localisation in cell leading edge|downregulation of protein localization in cell leading edge|negative regulation of protein localisation in cell leading edge|inhibition of protein localisation to cell leading edge|downregulation of protein localisation to cell leading edge|down regulation of protein localisation in cell leading edge|down-regulation of protein localization to cell leading edge|inhibition of protein localisation in cell leading edge|down regulation of protein localization to cell leading edge|downregulation of protein localisation in cell leading edge|negative regulation of protein localization in cell leading edge|down-regulation of protein localization in cell leading edge|inhibition of protein localization to cell leading edge|downregulation of protein localization to cell leading edge|negative regulation of protein localisation to cell leading edge|down-regulation of protein localisation to cell leading edge|down regulation of protein localization in cell leading edge|down regulation of protein localisation to cell leading edge http://purl.obolibrary.org/obo/GO_1905872 GO:0061023 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061023 GO:0061024 biolink:BiologicalProcess membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. go.json membrane organization and biogenesis|cellular membrane organisation|cellular membrane organization|membrane organisation|single-organism membrane organization http://purl.obolibrary.org/obo/GO_0061024 goslim_generic|goslim_pombe|goslim_pir|goslim_drosophila|goslim_chembl GO:1905862 biolink:CellularComponent ferroxidase complex A protein complex which is capable of ferroxidase activity. go.json http://purl.obolibrary.org/obo/GO_1905862 GO:1905863 biolink:BiologicalProcess obsolete invadopodium organization OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an invadopodium. go.json http://purl.obolibrary.org/obo/GO_1905863 GO:0061025 biolink:BiologicalProcess membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane. Wikipedia:Lipid_bilayer_fusion go.json cellular membrane fusion|single-organism membrane fusion http://purl.obolibrary.org/obo/GO_0061025 goslim_yeast GO:1905864 biolink:BiologicalProcess regulation of Atg1/ULK1 kinase complex assembly Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. go.json regulation of ATG1 kinase complex assembly|regulation of ULK1-ATG13-RB1CC1 complex assembly|regulation of ATG1/ULK1 signaling complex assembly|regulation of Atg1p signalling complex formation|regulation of ATG1-ATG13 complex assembly|regulation of ULK1-ATG13-FIP200 complex assembly|regulation of ULK1 signaling complex assembly|regulation of ULK1 signaling complex formation|regulation of ATG1-ATG13 complex formation|regulation of ULK1-ATG13-FIP200 complex formation|regulation of ATG1/ULK1 kinase complex formation|regulation of Atg1p signalling complex assembly|regulation of ATG1/ULK1 signaling complex formation|regulation of ULK1-ATG13-RB1CC1 complex formation|regulation of ATG1 kinase complex formation http://purl.obolibrary.org/obo/GO_1905864 GO:0061026 biolink:BiologicalProcess cardiac muscle tissue regeneration The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. go.json http://purl.obolibrary.org/obo/GO_0061026 GO:1905865 biolink:BiologicalProcess negative regulation of Atg1/ULK1 kinase complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. go.json down-regulation of ATG1/ULK1 kinase complex formation|inhibition of ULK1-ATG13-RB1CC1 complex formation|downregulation of ULK1-ATG13-RB1CC1 complex formation|negative regulation of ATG1/ULK1 kinase complex formation|downregulation of ATG1/ULK1 signaling complex assembly|negative regulation of ATG1-ATG13 complex assembly|inhibition of ATG1 kinase complex formation|downregulation of ATG1 kinase complex formation|down-regulation of ATG1-ATG13 complex assembly|down regulation of ATG1 kinase complex assembly|down-regulation of ULK1 signaling complex assembly|down regulation of ATG1/ULK1 kinase complex assembly|downregulation of Atg1p signalling complex formation|negative regulation of ULK1 signaling complex assembly|down regulation of ULK1-ATG13-RB1CC1 complex assembly|inhibition of ATG1 kinase complex assembly|down regulation of ATG1-ATG13 complex assembly|down-regulation of ULK1-ATG13-FIP200 complex formation|downregulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ULK1-ATG13-FIP200 complex formation|down regulation of ULK1 signaling complex assembly|inhibition of ULK1-ATG13-RB1CC1 complex assembly|down regulation of ATG1/ULK1 signaling complex assembly|down-regulation of ATG1 kinase complex assembly|negative regulation of ATG1 kinase complex assembly|negative regulation of Atg1p signalling complex assembly|downregulation of ULK1 signaling complex formation|downregulation of ATG1/ULK1 kinase complex assembly|down-regulation of ULK1-ATG13-RB1CC1 complex assembly|down regulation of Atg1p signalling complex formation|down-regulation of Atg1p signalling complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex assembly|inhibition of ATG1/ULK1 kinase complex assembly|down regulation of ULK1-ATG13-FIP200 complex formation|downregulation of ATG1-ATG13 complex formation|negative regulation of ATG1/ULK1 signaling complex formation|down-regulation of ATG1/ULK1 signaling complex formation|inhibition of ATG1/ULK1 signaling complex assembly|downregulation of ATG1-ATG13 complex assembly|negative regulation of ATG1/ULK1 signaling complex assembly|down regulation of ULK1-ATG13-FIP200 complex assembly|down-regulation of ATG1/ULK1 signaling complex assembly|inhibition of Atg1p signalling complex formation|inhibition of ATG1-ATG13 complex assembly|down-regulation of ULK1-ATG13-RB1CC1 complex formation|down-regulation of Atg1p signalling complex formation|inhibition of ULK1 signaling complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex formation|downregulation of ULK1 signaling complex assembly|negative regulation of Atg1p signalling complex formation|down regulation of Atg1p signalling complex assembly|downregulation of ATG1/ULK1 kinase complex formation|down regulation of ULK1 signaling complex formation|down-regulation of ATG1 kinase complex formation|negative regulation of ATG1 kinase complex formation|down regulation of ATG1/ULK1 signaling complex formation|inhibition of ULK1-ATG13-FIP200 complex assembly|down regulation of ATG1-ATG13 complex formation|down-regulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ULK1-ATG13-FIP200 complex assembly|inhibition of ULK1-ATG13-FIP200 complex formation|downregulation of ULK1-ATG13-FIP200 complex formation|inhibition of ULK1 signaling complex formation|down regulation of ULK1-ATG13-RB1CC1 complex formation|down-regulation of ULK1 signaling complex formation|inhibition of ATG1-ATG13 complex formation|down regulation of ATG1 kinase complex formation|downregulation of Atg1p signalling complex assembly|down regulation of ATG1/ULK1 kinase complex formation|inhibition of Atg1p signalling complex assembly|negative regulation of ULK1 signaling complex formation|downregulation of ATG1/ULK1 signaling complex formation|downregulation of ATG1 kinase complex assembly|down-regulation of ATG1-ATG13 complex formation|negative regulation of ATG1-ATG13 complex formation|inhibition of ATG1/ULK1 signaling complex formation|downregulation of ULK1-ATG13-RB1CC1 complex assembly|inhibition of ATG1/ULK1 kinase complex formation|down-regulation of ATG1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_1905865 GO:0061027 biolink:BiologicalProcess umbilical cord development The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. go.json http://purl.obolibrary.org/obo/GO_0061027 GO:1905866 biolink:BiologicalProcess positive regulation of Atg1/ULK1 kinase complex assembly Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. go.json up regulation of Atg1p signalling complex assembly|upregulation of ATG1/ULK1 kinase complex formation|activation of ULK1-ATG13-RB1CC1 complex assembly|activation of ULK1-ATG13-FIP200 complex formation|positive regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ULK1-ATG13-RB1CC1 complex formation|up-regulation of ATG1/ULK1 signaling complex assembly|upregulation of ATG1-ATG13 complex assembly|up regulation of ULK1-ATG13-FIP200 complex assembly|up regulation of ATG1/ULK1 signaling complex formation|up-regulation of ATG1 kinase complex formation|positive regulation of ULK1 signaling complex formation|up-regulation of Atg1p signalling complex formation|activation of ATG1/ULK1 signaling complex assembly|positive regulation of ATG1-ATG13 complex formation|positive regulation of Atg1p signalling complex assembly|upregulation of ULK1 signaling complex assembly|activation of Atg1p signalling complex assembly|up regulation of ULK1 signaling complex formation|activation of Atg1p signalling complex formation|up regulation of ULK1-ATG13-RB1CC1 complex formation|positive regulation of ATG1/ULK1 signaling complex formation|activation of ATG1/ULK1 signaling complex formation|up regulation of ATG1 kinase complex formation|positive regulation of ATG1/ULK1 kinase complex formation|upregulation of ULK1-ATG13-FIP200 complex formation|up regulation of ATG1-ATG13 complex formation|up-regulation of ULK1-ATG13-FIP200 complex assembly|positive regulation of ULK1-ATG13-RB1CC1 complex formation|activation of ULK1-ATG13-FIP200 complex assembly|activation of ULK1-ATG13-RB1CC1 complex formation|upregulation of ATG1 kinase complex assembly|positive regulation of ATG1 kinase complex formation|up-regulation of ATG1/ULK1 kinase complex assembly|upregulation of Atg1p signalling complex assembly|activation of ATG1 kinase complex formation|up regulation of ATG1/ULK1 kinase complex formation|up-regulation of ULK1 signaling complex formation|upregulation of ULK1-ATG13-RB1CC1 complex assembly|upregulation of ATG1/ULK1 signaling complex formation|activation of ULK1 signaling complex formation|up-regulation of ATG1-ATG13 complex formation|upregulation of ATG1/ULK1 signaling complex assembly|up-regulation of ATG1-ATG13 complex assembly|activation of ATG1-ATG13 complex formation|up-regulation of ATG1/ULK1 kinase complex formation|up regulation of ATG1/ULK1 kinase complex assembly|up-regulation of ULK1 signaling complex assembly|upregulation of ULK1-ATG13-RB1CC1 complex formation|positive regulation of ATG1 kinase complex assembly|upregulation of Atg1p signalling complex formation|activation of ATG1/ULK1 kinase complex formation|positive regulation of ULK1-ATG13-RB1CC1 complex assembly|upregulation of ATG1 kinase complex formation|activation of ATG1/ULK1 kinase complex assembly|upregulation of ULK1-ATG13-FIP200 complex assembly|up-regulation of ULK1-ATG13-FIP200 complex formation|up regulation of ATG1 kinase complex assembly|up regulation of ATG1-ATG13 complex assembly|up regulation of ULK1 signaling complex assembly|positive regulation of ATG1/ULK1 signaling complex assembly|up regulation of ULK1-ATG13-RB1CC1 complex assembly|up-regulation of Atg1p signalling complex assembly|upregulation of ULK1 signaling complex formation|activation of ATG1-ATG13 complex assembly|positive regulation of ATG1-ATG13 complex assembly|positive regulation of Atg1p signalling complex formation|up regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ATG1/ULK1 signaling complex formation|up-regulation of ATG1 kinase complex assembly|activation of ULK1 signaling complex assembly|positive regulation of ULK1 signaling complex assembly|upregulation of ATG1-ATG13 complex formation|up regulation of ATG1/ULK1 signaling complex assembly|upregulation of ATG1/ULK1 kinase complex assembly|activation of ATG1 kinase complex assembly|up regulation of Atg1p signalling complex formation|up-regulation of ULK1-ATG13-RB1CC1 complex assembly|positive regulation of ULK1-ATG13-FIP200 complex assembly http://purl.obolibrary.org/obo/GO_1905866 GO:0061028 biolink:BiologicalProcess establishment of endothelial barrier The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. go.json http://purl.obolibrary.org/obo/GO_0061028 GO:1905867 biolink:BiologicalProcess epididymis development The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure. go.json epididymus development http://purl.obolibrary.org/obo/GO_1905867 GO:0061029 biolink:BiologicalProcess eyelid development in camera-type eye The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. go.json http://purl.obolibrary.org/obo/GO_0061029 GO:1905868 biolink:BiologicalProcess regulation of 3'-UTR-mediated mRNA stabilization Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. go.json regulation of 3'-untranslated region-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_1905868 GO:1905869 biolink:BiologicalProcess negative regulation of 3'-UTR-mediated mRNA stabilization Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. go.json inhibition of 3'-UTR-mediated mRNA stabilization|negative regulation of 3'-untranslated region-mediated mRNA stabilization|down-regulation of 3'-untranslated region-mediated mRNA stabilization|down-regulation of 3'-UTR-mediated mRNA stabilization|downregulation of 3'-untranslated region-mediated mRNA stabilization|downregulation of 3'-UTR-mediated mRNA stabilization|down regulation of 3'-untranslated region-mediated mRNA stabilization|inhibition of 3'-untranslated region-mediated mRNA stabilization|down regulation of 3'-UTR-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_1905869 GO:0051690 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051690 GO:0051691 biolink:BiologicalProcess cellular oligosaccharide metabolic process The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells. go.json cellular oligosaccharide metabolism http://purl.obolibrary.org/obo/GO_0051691 GO:0051694 biolink:BiologicalProcess pointed-end actin filament capping The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. go.json pointed-end F-actin capping activity|minus-end F-actin capping activity|minus-end actin filament capping activity|pointed-end actin capping activity http://purl.obolibrary.org/obo/GO_0051694 GO:0002647 biolink:BiologicalProcess negative regulation of central tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction. go.json down-regulation of central tolerance induction|down regulation of central tolerance induction|inhibition of central tolerance induction|downregulation of central tolerance induction http://purl.obolibrary.org/obo/GO_0002647 GO:0002648 biolink:BiologicalProcess positive regulation of central tolerance induction Any process that activates or increases the frequency, rate, or extent of central tolerance induction. go.json up regulation of central tolerance induction|activation of central tolerance induction|stimulation of central tolerance induction|upregulation of central tolerance induction|up-regulation of central tolerance induction http://purl.obolibrary.org/obo/GO_0002648 GO:0051695 biolink:BiologicalProcess actin filament uncapping The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. go.json F-actin uncapping http://purl.obolibrary.org/obo/GO_0051695 GO:0051692 biolink:BiologicalProcess cellular oligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells. go.json cellular oligosaccharide breakdown|cellular oligosaccharide degradation|cellular oligosaccharide catabolism http://purl.obolibrary.org/obo/GO_0051692 GO:0002649 biolink:BiologicalProcess regulation of tolerance induction to self antigen Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen. go.json http://purl.obolibrary.org/obo/GO_0002649 GO:0051693 biolink:BiologicalProcess actin filament capping The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. go.json actin capping activity|F-actin capping activity http://purl.obolibrary.org/obo/GO_0051693 GO:0002654 biolink:BiologicalProcess positive regulation of tolerance induction dependent upon immune response Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response. go.json positive regulation of immune response-dependent tolerance induction|up regulation of tolerance induction dependent upon immune response|stimulation of tolerance induction dependent upon immune response|activation of tolerance induction dependent upon immune response|up-regulation of tolerance induction dependent upon immune response|upregulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002654 GO:0099600 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0099600 GO:0002655 biolink:BiologicalProcess regulation of tolerance induction to nonself antigen Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen. go.json http://purl.obolibrary.org/obo/GO_0002655 GO:0002656 biolink:BiologicalProcess negative regulation of tolerance induction to nonself antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen. go.json down regulation of tolerance induction to nonself antigen|inhibition of tolerance induction to nonself antigen|down-regulation of tolerance induction to nonself antigen|downregulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002656 GO:0002657 biolink:BiologicalProcess positive regulation of tolerance induction to nonself antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen. go.json up-regulation of tolerance induction to nonself antigen|activation of tolerance induction to nonself antigen|upregulation of tolerance induction to nonself antigen|up regulation of tolerance induction to nonself antigen|stimulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002657 GO:0002650 biolink:BiologicalProcess negative regulation of tolerance induction to self antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen. go.json down-regulation of tolerance induction to self antigen|down regulation of tolerance induction to self antigen|inhibition of tolerance induction to self antigen|downregulation of tolerance induction to self antigen http://purl.obolibrary.org/obo/GO_0002650 GO:0002651 biolink:BiologicalProcess positive regulation of tolerance induction to self antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen. go.json up regulation of tolerance induction to self antigen|activation of tolerance induction to self antigen|stimulation of tolerance induction to self antigen|upregulation of tolerance induction to self antigen|up-regulation of tolerance induction to self antigen http://purl.obolibrary.org/obo/GO_0002651 GO:0002652 biolink:BiologicalProcess regulation of tolerance induction dependent upon immune response Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response. go.json regulation of immune response-dependent tolerance induction http://purl.obolibrary.org/obo/GO_0002652 GO:0002653 biolink:BiologicalProcess negative regulation of tolerance induction dependent upon immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response. go.json downregulation of tolerance induction dependent upon immune response|negative regulation of immune response-dependent tolerance induction|down regulation of tolerance induction dependent upon immune response|inhibition of tolerance induction dependent upon immune response|down-regulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002653 GO:1905880 biolink:BiologicalProcess negative regulation of oogenesis Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. go.json down regulation of ovum development|down-regulation of oogenesis|inhibition of ovum development|down-regulation of ovum development|negative regulation of ovum development|down regulation of oogenesis|inhibition of oogenesis|downregulation of oogenesis|downregulation of ovum development http://purl.obolibrary.org/obo/GO_1905880 GO:0061010 biolink:BiologicalProcess gall bladder development The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile. go.json http://purl.obolibrary.org/obo/GO_0061010 GO:1905881 biolink:BiologicalProcess positive regulation of oogenesis Any process that activates or increases the frequency, rate or extent of oogenesis. go.json upregulation of oogenesis|upregulation of ovum development|positive regulation of ovum development|up-regulation of oogenesis|up regulation of ovum development|up regulation of oogenesis|up-regulation of ovum development|activation of oogenesis|activation of ovum development http://purl.obolibrary.org/obo/GO_1905881 GO:1905882 biolink:CellularComponent obsolete other organism cell wall OBSOLETE. Any cell wall that is part of a other organism. go.json http://purl.obolibrary.org/obo/GO_1905882 GO:0061011 biolink:BiologicalProcess hepatic duct development The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. go.json http://purl.obolibrary.org/obo/GO_0061011 GO:1905883 biolink:BiologicalProcess regulation of triglyceride transport Any process that modulates the frequency, rate or extent of triglyceride transport. go.json regulation of triacylglycerol transport http://purl.obolibrary.org/obo/GO_1905883 GO:0061012 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061012 GO:1905873 biolink:BiologicalProcess positive regulation of protein localization to cell leading edge Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. go.json activation of protein localization to cell leading edge|up-regulation of protein localization in cell leading edge|upregulation of protein localisation in cell leading edge|up-regulation of protein localisation to cell leading edge|up regulation of protein localization in cell leading edge|upregulation of protein localization to cell leading edge|up regulation of protein localisation to cell leading edge|positive regulation of protein localization in cell leading edge|activation of protein localization in cell leading edge|positive regulation of protein localisation to cell leading edge|activation of protein localisation to cell leading edge|up-regulation of protein localisation in cell leading edge|upregulation of protein localization in cell leading edge|up regulation of protein localisation in cell leading edge|up-regulation of protein localization to cell leading edge|upregulation of protein localisation to cell leading edge|positive regulation of protein localisation in cell leading edge|activation of protein localisation in cell leading edge|up regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1905873 GO:0061013 biolink:BiologicalProcess regulation of mRNA catabolic process Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. go.json regulation of mRNA decay http://purl.obolibrary.org/obo/GO_0061013 GO:1905874 biolink:BiologicalProcess regulation of postsynaptic density organization Any process that modulates the frequency, rate or extent of postsynaptic density organization. go.json regulation of post-synaptic density organization|regulation of postsynaptic density organisation|regulation of post synaptic density organization|regulation of PSD organization http://purl.obolibrary.org/obo/GO_1905874 GO:0061014 biolink:BiologicalProcess positive regulation of mRNA catabolic process Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. go.json positive regulation of mRNA decay http://purl.obolibrary.org/obo/GO_0061014 GO:1905875 biolink:BiologicalProcess negative regulation of postsynaptic density organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization. go.json inhibition of PSD organization|negative regulation of PSD organization|down-regulation of PSD organization|inhibition of postsynaptic density organization|downregulation of postsynaptic density organization|down-regulation of postsynaptic density organisation|negative regulation of postsynaptic density organisation|downregulation of post-synaptic density organization|down regulation of postsynaptic density organisation|downregulation of post synaptic density organization|down regulation of post-synaptic density organization|downregulation of PSD organization|downregulation of postsynaptic density organisation|inhibition of post-synaptic density organization|inhibition of postsynaptic density organisation|down-regulation of postsynaptic density organization|negative regulation of post-synaptic density organization|down-regulation of post-synaptic density organization|down regulation of post synaptic density organization|down regulation of PSD organization|inhibition of post synaptic density organization|down regulation of postsynaptic density organization|down-regulation of post synaptic density organization|negative regulation of post synaptic density organization http://purl.obolibrary.org/obo/GO_1905875 GO:0061015 biolink:BiologicalProcess snRNA import into nucleus The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus. go.json http://purl.obolibrary.org/obo/GO_0061015 GO:1905876 biolink:BiologicalProcess positive regulation of postsynaptic density organization Any process that activates or increases the frequency, rate or extent of postsynaptic density organization. go.json activation of postsynaptic density organisation|upregulation of post synaptic density organization|positive regulation of postsynaptic density organisation|positive regulation of post-synaptic density organization|upregulation of PSD organization|up-regulation of postsynaptic density organization|up regulation of post-synaptic density organization|positive regulation of post synaptic density organization|upregulation of postsynaptic density organisation|positive regulation of PSD organization|up regulation of postsynaptic density organization|up-regulation of post-synaptic density organization|activation of post-synaptic density organization|up regulation of post synaptic density organization|activation of postsynaptic density organization|up regulation of PSD organization|up-regulation of post synaptic density organization|activation of post synaptic density organization|activation of PSD organization|up-regulation of PSD organization|up-regulation of postsynaptic density organisation|upregulation of postsynaptic density organization|upregulation of post-synaptic density organization|up regulation of postsynaptic density organisation http://purl.obolibrary.org/obo/GO_1905876 GO:0061016 biolink:BiologicalProcess snRNA localization to Cajal body The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body. go.json http://purl.obolibrary.org/obo/GO_0061016 GO:0061017 biolink:BiologicalProcess hepatoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. go.json http://purl.obolibrary.org/obo/GO_0061017 GO:1905877 biolink:BiologicalProcess obsolete invadopodium assembly OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form an invadopodium. go.json invadopodium formation http://purl.obolibrary.org/obo/GO_1905877 GO:0061018 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061018 GO:1905878 biolink:BiologicalProcess obsolete invadopodium disassembly OBSOLETE. The disaggregation of an invadopodium into its constituent components. go.json http://purl.obolibrary.org/obo/GO_1905878 GO:0061019 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061019 GO:1905879 biolink:BiologicalProcess regulation of oogenesis Any process that modulates the frequency, rate or extent of oogenesis. go.json regulation of ovum development http://purl.obolibrary.org/obo/GO_1905879 GO:0099609 biolink:MolecularActivity microtubule lateral binding Interacting selectively and non-covalently with the side of a microtubule. go.json http://purl.obolibrary.org/obo/GO_0099609 GO:0099607 biolink:BiologicalProcess lateral attachment of mitotic spindle microtubules to kinetochore The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate). go.json http://purl.obolibrary.org/obo/GO_0099607 GO:0099608 biolink:BiologicalProcess regulation of action potential firing pattern Any process that regulates the temporal pattern of a sequence of action potentials in a neuron. go.json spike train sculpting http://purl.obolibrary.org/obo/GO_0099608 GO:0099605 biolink:BiologicalProcess regulation of action potential firing rate Any process that regulates the frequency of action potentials in a spike train. go.json http://purl.obolibrary.org/obo/GO_0099605 GO:0099606 biolink:BiologicalProcess microtubule plus-end directed mitotic chromosome migration The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression. go.json plus-end directed chromosome gliding http://purl.obolibrary.org/obo/GO_0099606 GO:0099603 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0099603 GO:0002658 biolink:BiologicalProcess regulation of peripheral tolerance induction Any process that modulates the frequency, rate, or extent of peripheral tolerance induction. go.json http://purl.obolibrary.org/obo/GO_0002658 GO:0002659 biolink:BiologicalProcess negative regulation of peripheral tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction. go.json inhibition of peripheral tolerance induction|down-regulation of peripheral tolerance induction|downregulation of peripheral tolerance induction|down regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002659 GO:0099604 biolink:MolecularActivity ligand-gated calcium channel activity Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. go.json http://purl.obolibrary.org/obo/GO_0099604 GO:0099601 biolink:BiologicalProcess regulation of neurotransmitter receptor activity Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. go.json http://purl.obolibrary.org/obo/GO_0099601 goslim_synapse GO:0099602 biolink:MolecularActivity neurotransmitter receptor regulator activity A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing. go.json http://purl.obolibrary.org/obo/GO_0099602 GO:0036080 biolink:MolecularActivity purine nucleotide-sugar transmembrane transporter activity Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. go.json http://purl.obolibrary.org/obo/GO_0036080 GO:0036081 biolink:MolecularActivity extracellular ammonia-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts. go.json ionotropic ammonia receptor activity http://purl.obolibrary.org/obo/GO_0036081 GO:0036079 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036079 GO:0036071 biolink:BiologicalProcess N-glycan fucosylation The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains. go.json glycoprotein fucosylation http://purl.obolibrary.org/obo/GO_0036071 GO:0036072 biolink:BiologicalProcess direct ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. go.json http://purl.obolibrary.org/obo/GO_0036072 GO:0036073 biolink:BiologicalProcess perichondral ossification Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage. go.json http://purl.obolibrary.org/obo/GO_0036073 GO:0036074 biolink:BiologicalProcess metaplastic ossification Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division. go.json metaplasia http://purl.obolibrary.org/obo/GO_0036074 GO:0036075 biolink:BiologicalProcess replacement ossification Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. go.json indirect ossification http://purl.obolibrary.org/obo/GO_0036075 GO:0036076 biolink:BiologicalProcess ligamentous ossification Ossification wherein bone tissue forms within ligamentous tissue. go.json http://purl.obolibrary.org/obo/GO_0036076 GO:0036077 biolink:BiologicalProcess intratendonous ossification Ossification wherein bone tissue forms within tendonous tissue. go.json http://purl.obolibrary.org/obo/GO_0036077 GO:0036078 biolink:BiologicalProcess minus-end specific microtubule depolymerization The removal of tubulin heterodimers from the minus end of a microtubule. go.json http://purl.obolibrary.org/obo/GO_0036078 GO:0036070 biolink:BiologicalProcess light-independent bacteriochlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants. go.json light-independent bacteriochlorophyll biosynthesis|light-independent bacteriochlorophyll synthesis|light-independent bacteriochlorophyll formation|light-independent bacteriochlorophyll anabolism|light independent bacteriochlorophyll biosynthetic process http://purl.obolibrary.org/obo/GO_0036070 GO:0036068 biolink:BiologicalProcess light-independent chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light. go.json light-independent chlorophyll anabolism|light independent chlorophyll biosynthetic process|light-independent chlorophyll synthesis|light-independent chlorophyll formation|light-independent chlorophyll biosynthesis http://purl.obolibrary.org/obo/GO_0036068 GO:0036069 biolink:BiologicalProcess light-dependent bacteriochlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants. go.json light-dependent bacteriochlorophyll synthesis|light-dependent bacteriochlorophyll formation|light dependent bacteriochlorophyll biosynthetic process|light-dependent bacteriochlorophyll biosynthesis|light-dependent bacteriochlorophyll anabolism http://purl.obolibrary.org/obo/GO_0036069 GO:0036060 biolink:BiologicalProcess slit diaphragm assembly The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration. go.json http://purl.obolibrary.org/obo/GO_0036060 GO:0036061 biolink:BiologicalProcess muscle cell chemotaxis toward tendon cell The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells. go.json muscle cell attraction|muscle cell chemotaxis towards tendon cell http://purl.obolibrary.org/obo/GO_0036061 GO:0036062 biolink:CellularComponent presynaptic periactive zone A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development. go.json pre-synaptic periactive zone|periactive zone http://purl.obolibrary.org/obo/GO_0036062 GO:0036063 biolink:CellularComponent acroblast A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle. go.json spermatid acroblast http://purl.obolibrary.org/obo/GO_0036063 GO:0036064 biolink:CellularComponent ciliary basal body A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. NIF_Subcellular:sao11978067 go.json cilial basal body|microtubule basal body|kinetosome|basal body|cilium basal body http://purl.obolibrary.org/obo/GO_0036064 GO:0036065 biolink:BiologicalProcess fucosylation The covalent attachment of a fucosyl group to an acceptor molecule. go.json http://purl.obolibrary.org/obo/GO_0036065 GO:0036066 biolink:BiologicalProcess protein O-linked fucosylation The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage. go.json http://purl.obolibrary.org/obo/GO_0036066 GO:0036067 biolink:BiologicalProcess light-dependent chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light. go.json light-dependent chlorophyll biosynthesis|light-dependent chlorophyll synthesis|light-dependent chlorophyll formation|light dependent chlorophyll biosynthetic process|light-dependent chlorophyll anabolism http://purl.obolibrary.org/obo/GO_0036067 GO:0036057 biolink:CellularComponent slit diaphragm A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration. go.json http://purl.obolibrary.org/obo/GO_0036057 GO:0036058 biolink:BiologicalProcess filtration diaphragm assembly The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph. go.json http://purl.obolibrary.org/obo/GO_0036058 GO:0036059 biolink:BiologicalProcess nephrocyte diaphragm assembly The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney. go.json http://purl.obolibrary.org/obo/GO_0036059 GO:0036050 biolink:BiologicalProcess peptidyl-lysine succinylation The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine. RESID:AA0545 go.json http://purl.obolibrary.org/obo/GO_0036050 GO:0036051 biolink:BiologicalProcess protein localization to trailing edge A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement. go.json protein localisation to trailing edge http://purl.obolibrary.org/obo/GO_0036051 GO:0036052 biolink:BiologicalProcess protein localization to uropod A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell. go.json protein localisation to uropod http://purl.obolibrary.org/obo/GO_0036052 GO:0036053 biolink:CellularComponent glomerular endothelium fenestra A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes. go.json GEnC fenestration|glomerular endothelial cell fenestration http://purl.obolibrary.org/obo/GO_0036053 GO:0036054 biolink:MolecularActivity protein-malonyllysine demalonylase activity Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide. go.json peptidyl-malonyllysine demalonylase activity|protein malonyl lysine demalonylation activity|protein lysine demalonylation activity http://purl.obolibrary.org/obo/GO_0036054 GO:0036055 biolink:MolecularActivity protein-succinyllysine desuccinylase activity Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. RHEA:47668 go.json peptidyl-succinyllysine desuccinylase activity|succinyl lysine desuccinylase activity|succinyllysine desuccinylase activity http://purl.obolibrary.org/obo/GO_0036055 GO:0036056 biolink:CellularComponent filtration diaphragm A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph. go.json http://purl.obolibrary.org/obo/GO_0036056 GO:0036046 biolink:BiologicalProcess protein demalonylation The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide. go.json http://purl.obolibrary.org/obo/GO_0036046 GO:0036047 biolink:BiologicalProcess peptidyl-lysine demalonylation The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein. go.json http://purl.obolibrary.org/obo/GO_0036047 GO:0036048 biolink:BiologicalProcess protein desuccinylation The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein. go.json http://purl.obolibrary.org/obo/GO_0036048 GO:0036049 biolink:BiologicalProcess peptidyl-lysine desuccinylation The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein. go.json http://purl.obolibrary.org/obo/GO_0036049 GO:0036040 biolink:BiologicalProcess curcumin catabolic process The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin. go.json (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolism|turmeric yellow breakdown|curcumin breakdown|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione degradation|diferuloylmethane catabolism|diferuloylmethane breakdown|curcumin catabolism|turmeric yellow catabolism|turmeric yellow catabolic process|diferuloylmethane catabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione breakdown|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolic process|turmeric yellow degradation|curcumin degradation|diferuloylmethane degradation http://purl.obolibrary.org/obo/GO_0036040 GO:0036041 biolink:MolecularActivity long-chain fatty acid binding Interacting selectively and non-covalently with a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go.json long chain fatty acid binding http://purl.obolibrary.org/obo/GO_0036041 GO:0036042 biolink:MolecularActivity long-chain fatty acyl-CoA binding Interacting selectively and non-covalently with a long-chain fatty acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. go.json long-chain fatty acyl-coenyme A binding http://purl.obolibrary.org/obo/GO_0036042 GO:0036043 biolink:CellularComponent obsolete microspike OBSOLETE. A dynamic, actin-rich projection extending from the surface of a migrating animal cell. go.json microspike http://purl.obolibrary.org/obo/GO_0036043 GO:0036044 biolink:BiologicalProcess obsolete protein malonylation OBSOLETE. The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group. go.json protein malonylation http://purl.obolibrary.org/obo/GO_0036044 GO:0036045 biolink:BiologicalProcess obsolete peptidyl-lysine malonylation OBSOLETE. The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine. go.json lysine malonylation|peptidyl-lysine malonylation http://purl.obolibrary.org/obo/GO_0036045 GO:0036035 biolink:BiologicalProcess osteoclast development The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. go.json osteoclast cell development http://purl.obolibrary.org/obo/GO_0036035 GO:0036036 biolink:BiologicalProcess cardiac neural crest cell delamination The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube. go.json http://purl.obolibrary.org/obo/GO_0036036 GO:0036037 biolink:BiologicalProcess CD8-positive, alpha-beta T cell activation The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go.json http://purl.obolibrary.org/obo/GO_0036037 GO:0036038 biolink:CellularComponent MKS complex A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane. go.json B9 complex|MKS module|tectonic complex|tectonic-like complex|TCTN-B9D complex http://purl.obolibrary.org/obo/GO_0036038 GO:0036039 biolink:BiologicalProcess curcumin metabolic process The chemical reactions and pathways involving the polyphenol, curcumin. go.json diferuloylmethane metabolism|curcumin metabolism|turmeric yellow metabolism|turmeric yellow metabolic process|diferuloylmethane metabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism http://purl.obolibrary.org/obo/GO_0036039 GO:0036030 biolink:CellularComponent protein C inhibitor-plasma kallikrein complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein. go.json SERPINA5-plasma kallikrein complex|PCI-plasma kallikrein complex|protein C inhibitor-KLKB1 complex|plasma serine protease inhibitor-plasma kallikrein complex|serpin A5-plasma kallikrein complex http://purl.obolibrary.org/obo/GO_0036030 GO:0036031 biolink:BiologicalProcess recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript. go.json recruitment of guanylyltransferase to RNA polymerase II holoenzyme complex|capping enzyme targeting to RNA polymerase II http://purl.obolibrary.org/obo/GO_0036031 GO:0036032 biolink:BiologicalProcess neural crest cell delamination The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube. go.json neural crest cell emigration|neural crest cell segregation|neural crest cell individualization http://purl.obolibrary.org/obo/GO_0036032 GO:0036033 biolink:MolecularActivity mediator complex binding Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. go.json http://purl.obolibrary.org/obo/GO_0036033 GO:0036034 biolink:BiologicalProcess mediator complex assembly The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. go.json http://purl.obolibrary.org/obo/GO_0036034 GO:0051600 biolink:BiologicalProcess regulation of endocytosis by exocyst localization Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. go.json regulation of endocytosis by exocyst localisation|regulation of site selection of endocytosis|spatial regulation of endocytosis|relocation of endocytosis http://purl.obolibrary.org/obo/GO_0051600 GO:0051603 biolink:BiologicalProcess proteolysis involved in cellular protein catabolic process The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. go.json proteolysis during cellular protein catabolism|peptidolysis during cellular protein catabolism|peptidolysis during cellular protein catabolic process|peptidolysis involved in cellular protein catabolic process|peptidolysis involved in cellular protein catabolism|proteolysis during cellular protein catabolic process http://purl.obolibrary.org/obo/GO_0051603 goslim_yeast GO:0051604 biolink:BiologicalProcess protein maturation Any process leading to the attainment of the full functional capacity of a protein. go.json http://purl.obolibrary.org/obo/GO_0051604 goslim_yeast|goslim_generic|goslim_pombe|goslim_pir|goslim_chembl|goslim_drosophila GO:0051601 biolink:BiologicalProcess exocyst localization Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. go.json exocyst localisation|establishment and maintenance of exocyst localization http://purl.obolibrary.org/obo/GO_0051601 GO:0051602 biolink:BiologicalProcess response to electrical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. go.json response to electricity http://purl.obolibrary.org/obo/GO_0051602 GO:0051607 biolink:BiologicalProcess defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism. go.json antiviral response|defence response to virus|defense response to viruses http://purl.obolibrary.org/obo/GO_0051607 GO:0051608 biolink:BiologicalProcess histamine transport The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go.json http://purl.obolibrary.org/obo/GO_0051608 GO:0051605 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051605 GO:0051606 biolink:BiologicalProcess detection of stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. go.json stimulus sensing|stimulus detection|perception of stimulus http://purl.obolibrary.org/obo/GO_0051606 goslim_pir GO:0051609 biolink:BiologicalProcess inhibition of neurotransmitter uptake Any process that prevents the activation of the directed movement of a neurotransmitter into a cell. go.json inhibition of neurotransmitter import http://purl.obolibrary.org/obo/GO_0051609 GO:0036024 biolink:CellularComponent protein C inhibitor-TMPRSS7 complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7. go.json plasma serine protease inhibitor-TMPRSS7 complex|protein C inhibitor-matriptase-3 complex|serpin A5-TMPRSS7 complex|SERPINA5-TMPRSS7 complex|protein C inhibitor-transmembrane protease serine 7 complex|PCI-TMPRSS7 complex http://purl.obolibrary.org/obo/GO_0036024 GO:0036025 biolink:CellularComponent protein C inhibitor-TMPRSS11E complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E. go.json protein C inhibitor-transmembrane protease serine 11E complex|PCI-TMPRSS11E complex|plasma serine protease inhibitor-TMPRSS11E complex|serpin A5-TMPRSS11E complex|SERPINA5-TMPRSS11E complex http://purl.obolibrary.org/obo/GO_0036025 GO:0036026 biolink:CellularComponent protein C inhibitor-PLAT complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator. go.json SERPINA5-PLAT complex|protein C inhibitor-tPA complex|serpin A5-PLAT complex|plasma serine protease inhibitor-PLAT complex|protein C inhibitor-tissue-type plasminogen activator complex|PCI-PLAT complex http://purl.obolibrary.org/obo/GO_0036026 GO:0036027 biolink:CellularComponent protein C inhibitor-PLAU complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator. go.json SERPINA5-PLAU complex|serpin A5-PLAU complex|protein C inhibitor-uPA complex|protein C inhibitor-urokinase-type plasminogen activator complex|plasma serine protease inhibitor-PLAU complex|protein C inhibitor-U-plasminogen activator complex|PCI-PLAU complex http://purl.obolibrary.org/obo/GO_0036027 GO:0036028 biolink:CellularComponent protein C inhibitor-thrombin complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin. go.json protein C inhibitor-coagulation factor II complex|PCI-thrombin complex|SERPINA5-thrombin complex|protein C inhibitor-F2 complex|serpin A5-thrombin complex|plasma serine protease inhibitor-thrombin complex http://purl.obolibrary.org/obo/GO_0036028 GO:0036029 biolink:CellularComponent protein C inhibitor-KLK3 complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen. go.json plasma serine protease inhibitor-KLK3 complex|protein C inhibitor-kallikrein-3 complex|PCI-KLK3 complex|SERPINA5-KLK3 complex|protein C inhibitor-prostate-specific antigen complex|serpin A5-KLK3 complex http://purl.obolibrary.org/obo/GO_0036029 GO:0036020 biolink:CellularComponent endolysosome membrane The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome. go.json endolysosomal membrane http://purl.obolibrary.org/obo/GO_0036020 GO:0036021 biolink:CellularComponent endolysosome lumen The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome. go.json endolysosomal lumen http://purl.obolibrary.org/obo/GO_0036021 GO:0036022 biolink:BiologicalProcess limb joint morphogenesis The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. go.json knee morphogenesis|leg joint morphogenesis http://purl.obolibrary.org/obo/GO_0036022 GO:0036023 biolink:BiologicalProcess embryonic skeletal limb joint morphogenesis The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb. go.json http://purl.obolibrary.org/obo/GO_0036023 GO:0051610 biolink:BiologicalProcess serotonin uptake The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. go.json serotonin import|5-hydroxytryptamine uptake|5HT uptake|5-HT uptake http://purl.obolibrary.org/obo/GO_0051610 GO:0051611 biolink:BiologicalProcess regulation of serotonin uptake Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell. go.json regulation of 5-HT uptake|regulation of serotonin import|regulation of 5-hydroxytryptamine uptake|regulation of 5HT uptake http://purl.obolibrary.org/obo/GO_0051611 GO:0051614 biolink:BiologicalProcess inhibition of serotonin uptake Any process that prevents the activation of the directed movement of serotonin into a cell. go.json inhibition of 5-hydroxytryptamine uptake|inhibition of 5HT uptake|inhibition of 5-HT uptake|inhibition of serotonin import http://purl.obolibrary.org/obo/GO_0051614 GO:0051615 biolink:BiologicalProcess histamine uptake The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go.json histamine import http://purl.obolibrary.org/obo/GO_0051615 GO:0051612 biolink:BiologicalProcess negative regulation of serotonin uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell. go.json downregulation of serotonin uptake|down regulation of serotonin uptake|down-regulation of serotonin uptake|negative regulation of serotonin import|negative regulation of 5-hydroxytryptamine uptake|negative regulation of 5-HT uptake|negative regulation of 5HT uptake http://purl.obolibrary.org/obo/GO_0051612 GO:0051613 biolink:BiologicalProcess positive regulation of serotonin uptake Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell. go.json positive regulation of 5-hydroxytryptamine uptake|up-regulation of serotonin uptake|activation of serotonin uptake|positive regulation of 5HT uptake|upregulation of serotonin uptake|positive regulation of 5-HT uptake|positive regulation of serotonin import|up regulation of serotonin uptake|stimulation of serotonin uptake http://purl.obolibrary.org/obo/GO_0051613 GO:0051618 biolink:BiologicalProcess positive regulation of histamine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell. go.json upregulation of histamine uptake|positive regulation of histamine import|up regulation of histamine uptake|stimulation of histamine uptake|activation of histamine uptake|up-regulation of histamine uptake http://purl.obolibrary.org/obo/GO_0051618 GO:0051619 biolink:BiologicalProcess inhibition of histamine uptake Any process that prevents the activation of the directed movement of histamine into a cell. go.json inhibition of histamine import http://purl.obolibrary.org/obo/GO_0051619 GO:0051616 biolink:BiologicalProcess regulation of histamine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell. go.json regulation of histamine import http://purl.obolibrary.org/obo/GO_0051616 GO:0051617 biolink:BiologicalProcess negative regulation of histamine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell. go.json down-regulation of histamine uptake|negative regulation of histamine import|downregulation of histamine uptake|down regulation of histamine uptake http://purl.obolibrary.org/obo/GO_0051617 GO:0036013 biolink:CellularComponent cyanelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope. go.json http://purl.obolibrary.org/obo/GO_0036013 GO:0036014 biolink:CellularComponent cyanelle intermembrane space The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer. go.json cyanelle periplasm|cyanelle envelope lumen http://purl.obolibrary.org/obo/GO_0036014 GO:0036015 biolink:BiologicalProcess response to interleukin-3 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus. go.json response to IL-3 http://purl.obolibrary.org/obo/GO_0036015 GO:0036016 biolink:BiologicalProcess cellular response to interleukin-3 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus. go.json cellular response to IL-3 http://purl.obolibrary.org/obo/GO_0036016 GO:0036017 biolink:BiologicalProcess response to erythropoietin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis. go.json http://purl.obolibrary.org/obo/GO_0036017 GO:0036018 biolink:BiologicalProcess cellular response to erythropoietin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. go.json http://purl.obolibrary.org/obo/GO_0036018 GO:0036019 biolink:CellularComponent endolysosome An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place. go.json http://purl.obolibrary.org/obo/GO_0036019 GO:0036010 biolink:BiologicalProcess protein localization to endosome A process in which a protein is transported to, or maintained in, a location within an endosome. go.json protein localization in endosome|protein localisation in endosome http://purl.obolibrary.org/obo/GO_0036010 GO:0036011 biolink:BiologicalProcess imaginal disc-derived leg segmentation Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint. go.json http://purl.obolibrary.org/obo/GO_0036011 GO:0036012 biolink:CellularComponent cyanelle inner membrane The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma. go.json cyanelle inner envelope membrane http://purl.obolibrary.org/obo/GO_0036012 GO:0051621 biolink:BiologicalProcess regulation of norepinephrine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. go.json regulation of noradrenaline uptake|regulation of levarterenol uptake|regulation of norepinephrine import http://purl.obolibrary.org/obo/GO_0051621 GO:0051622 biolink:BiologicalProcess negative regulation of norepinephrine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. go.json negative regulation of levarterenol uptake|down-regulation of norepinephrine uptake|negative regulation of norepinephrine import|down regulation of norepinephrine uptake|downregulation of norepinephrine uptake|negative regulation of noradrenaline uptake http://purl.obolibrary.org/obo/GO_0051622 GO:0051620 biolink:BiologicalProcess norepinephrine uptake The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. go.json norepinephrine reuptake|levarterenol uptake|noradrenaline reuptake|norepinephrine import|noradrenaline uptake|levarterenol reuptake http://purl.obolibrary.org/obo/GO_0051620 GO:0051625 biolink:BiologicalProcess epinephrine uptake The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. go.json epinephrine reuptake|adrenaline reuptake|adrenaline uptake|epinephrine import http://purl.obolibrary.org/obo/GO_0051625 GO:0051626 biolink:BiologicalProcess regulation of epinephrine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell. go.json regulation of epinephrine import|regulation of adrenaline uptake http://purl.obolibrary.org/obo/GO_0051626 GO:0051623 biolink:BiologicalProcess positive regulation of norepinephrine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. go.json positive regulation of norepinephrine import|stimulation of norepinephrine uptake|upregulation of norepinephrine uptake|up-regulation of norepinephrine uptake|up regulation of norepinephrine uptake|positive regulation of levarterenol uptake|activation of norepinephrine uptake|positive regulation of noradrenaline uptake http://purl.obolibrary.org/obo/GO_0051623 GO:0051624 biolink:BiologicalProcess inhibition of norepinephrine uptake Any process that prevents the activation of the directed movement of norepinephrine into a cell. go.json inhibition of norepinephrine import|inhibition of levarterenol uptake|inhibition of noradrenaline uptake http://purl.obolibrary.org/obo/GO_0051624 GO:0051629 biolink:BiologicalProcess inhibition of epinephrine uptake Any process that prevents the activation of the directed movement of epinephrine into a cell. go.json inhibition of epinephrine import|inhibition of adrenaline uptake http://purl.obolibrary.org/obo/GO_0051629 GO:0051627 biolink:BiologicalProcess negative regulation of epinephrine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell. go.json downregulation of epinephrine uptake|down regulation of epinephrine uptake|negative regulation of adrenaline uptake|down-regulation of epinephrine uptake|negative regulation of epinephrine import http://purl.obolibrary.org/obo/GO_0051627 GO:0051628 biolink:BiologicalProcess positive regulation of epinephrine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell. go.json positive regulation of epinephrine import|stimulation of epinephrine uptake|up regulation of epinephrine uptake|activation of epinephrine uptake|up-regulation of epinephrine uptake|positive regulation of adrenaline uptake|upregulation of epinephrine uptake http://purl.obolibrary.org/obo/GO_0051628 GO:0036002 biolink:MolecularActivity pre-mRNA binding Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule. go.json protein-coding primary transcript binding http://purl.obolibrary.org/obo/GO_0036002 GO:0036003 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go.json http://purl.obolibrary.org/obo/GO_0036003 GO:0036004 biolink:MolecularActivity GAF domain binding Interacting selectively and non-covalently with the GAF domain of a protein. go.json http://purl.obolibrary.org/obo/GO_0036004 GO:0036005 biolink:BiologicalProcess response to macrophage colony-stimulating factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. go.json response to macrophage colony-stimulating factor|response to M-CSF|response to macrophage colony-stimulating factor stimulus http://purl.obolibrary.org/obo/GO_0036005 GO:0036006 biolink:BiologicalProcess cellular response to macrophage colony-stimulating factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. go.json cellular response to M-CSF stimulus|cellular response to macrophage colony-stimulating factor http://purl.obolibrary.org/obo/GO_0036006 GO:0036007 biolink:CellularComponent scintillon A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen. go.json http://purl.obolibrary.org/obo/GO_0036007 GO:0036008 biolink:BiologicalProcess sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate. MetaCyc:SUCUTIL-PWY go.json http://purl.obolibrary.org/obo/GO_0036008 GO:0036009 biolink:MolecularActivity protein-glutamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine. Reactome:R-HSA-6800138 go.json http://purl.obolibrary.org/obo/GO_0036009 GO:0036000 biolink:CellularComponent mucocyst A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion. go.json http://purl.obolibrary.org/obo/GO_0036000 GO:0036001 biolink:BiologicalProcess 'de novo' pyridoxal 5'-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components. MetaCyc:PYRIDOXSYN-PWY go.json 'de novo' pyridoxal 5'-phosphate anabolism|'de novo' pyridoxal 5'-phosphate synthesis|'de novo' pyridoxal 5'-phosphate formation|'de novo' pyridoxal phosphate biosynthetic process|'de novo' pyridoxal 5'-phosphate biosynthesis|'de novo' PLP biosynthesis http://purl.obolibrary.org/obo/GO_0036001 GO:0120057 biolink:BiologicalProcess regulation of small intestinal transit Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. go.json regulation of small intestine transit|regulation of small bowel transit http://purl.obolibrary.org/obo/GO_0120057 GO:0120058 biolink:BiologicalProcess positive regulation of small intestinal transit Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. go.json positive regulation of small bowel transit|positive regulation of small intestine transit http://purl.obolibrary.org/obo/GO_0120058 GO:0120059 biolink:BiologicalProcess negative regulation of small intestinal transit Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. go.json negative regulation of small intestine transit|negative regulation of small bowel transit http://purl.obolibrary.org/obo/GO_0120059 GO:0120053 biolink:MolecularActivity ribitol beta-1,4-xylosyltransferase activity Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R. go.json http://purl.obolibrary.org/obo/GO_0120053 GO:0120054 biolink:BiologicalProcess intestinal motility Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth). go.json http://purl.obolibrary.org/obo/GO_0120054 GO:0120055 biolink:BiologicalProcess small intestinal transit Migration of ingested material along the length of the small intestine. go.json small intestine transit|small bowel transit http://purl.obolibrary.org/obo/GO_0120055 GO:0120056 biolink:BiologicalProcess large intestinal transit Migration of ingested material along the length of the large intestine. go.json colon transit|large bowel transit|colonic transit|large intestine transit http://purl.obolibrary.org/obo/GO_0120056 GO:0120068 biolink:BiologicalProcess regulation of stomach fundus smooth muscle contraction Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction. go.json http://purl.obolibrary.org/obo/GO_0120068 GO:0120069 biolink:BiologicalProcess positive regulation of stomach fundus smooth muscle contraction Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction. go.json http://purl.obolibrary.org/obo/GO_0120069 GO:0120064 biolink:BiologicalProcess stomach pylorus smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach. go.json http://purl.obolibrary.org/obo/GO_0120064 GO:0120065 biolink:BiologicalProcess pyloric antrum smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach. go.json antrum smooth muscle contraction http://purl.obolibrary.org/obo/GO_0120065 GO:0120066 biolink:BiologicalProcess pyloric canal smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter. go.json http://purl.obolibrary.org/obo/GO_0120066 GO:0120067 biolink:BiologicalProcess pyloric sphincter smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum. go.json http://purl.obolibrary.org/obo/GO_0120067 GO:0120060 biolink:BiologicalProcess regulation of gastric emptying Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. go.json regulation of small bowel emptying|regulation of small intestine emptying http://purl.obolibrary.org/obo/GO_0120060 GO:0120061 biolink:BiologicalProcess negative regulation of gastric emptying Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. go.json http://purl.obolibrary.org/obo/GO_0120061 GO:0120062 biolink:BiologicalProcess positive regulation of gastric emptying Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. go.json http://purl.obolibrary.org/obo/GO_0120062 GO:0120063 biolink:BiologicalProcess stomach smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach. go.json http://purl.obolibrary.org/obo/GO_0120063 GO:0120079 biolink:BiologicalProcess regulation of microfilament motor activity Any process that modulates the frequency, rate or extent of microfilament motor activity. go.json regulation of actin-activated ATPase activity|regulation of myosin ATPase activity|regulation of actin-filament motor activity|regulation of muscle motor activity|regulation of actin-dependent ATPase activity|regulation of actin filament motor activity http://purl.obolibrary.org/obo/GO_0120079 GO:0120075 biolink:BiologicalProcess positive regulation of endocardial cushion cell differentiation Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation. go.json http://purl.obolibrary.org/obo/GO_0120075 GO:0120076 biolink:BiologicalProcess negative regulation of endocardial cushion cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation. go.json http://purl.obolibrary.org/obo/GO_0120076 GO:0120077 biolink:BiologicalProcess angiogenic sprout fusion The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis. go.json blood vessel anastomosis|angiogenic sprout fusion http://purl.obolibrary.org/obo/GO_0120077 GO:0120078 biolink:BiologicalProcess cell adhesion involved in sprouting angiogenesis The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network. go.json cell adhesion involved in vascular anastomosis|cell adhesion involved in blood vessel anastomosis http://purl.obolibrary.org/obo/GO_0120078 GO:0120071 biolink:BiologicalProcess regulation of pyloric antrum smooth muscle contraction Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction. go.json http://purl.obolibrary.org/obo/GO_0120071 GO:0120072 biolink:BiologicalProcess positive regulation of pyloric antrum smooth muscle contraction Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction. go.json http://purl.obolibrary.org/obo/GO_0120072 GO:0120073 biolink:BiologicalProcess negative regulation of pyloric antrum smooth muscle contraction Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction. go.json http://purl.obolibrary.org/obo/GO_0120073 GO:0120074 biolink:BiologicalProcess regulation of endocardial cushion cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell. go.json http://purl.obolibrary.org/obo/GO_0120074 GO:0120070 biolink:BiologicalProcess negative regulation of stomach fundus smooth muscle contraction Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction. go.json http://purl.obolibrary.org/obo/GO_0120070 GO:0120086 biolink:MolecularActivity (3S)-(+)-asterisca-2(9),6-diene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene. go.json asterisca-2(9),6-diene synthase activity http://purl.obolibrary.org/obo/GO_0120086 GO:0120082 biolink:CellularComponent smooth endoplasmic reticulum cisterna A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity. go.json http://purl.obolibrary.org/obo/GO_0120082 GO:0120083 biolink:CellularComponent rough endoplasmic reticulum cisterna A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity. go.json http://purl.obolibrary.org/obo/GO_0120083 GO:0120084 biolink:BiologicalProcess endothelial tip cell filopodium assembly The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout. go.json http://purl.obolibrary.org/obo/GO_0120084 GO:0120085 biolink:BiologicalProcess transposon integration involved in RNA-mediated transposition Any transposon integration that contributes to a process of RNA-mediated transposition. go.json retrotransposon integration http://purl.obolibrary.org/obo/GO_0120085 GO:0120080 biolink:BiologicalProcess negative regulation of microfilament motor activity Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity. go.json negative regulation of actin filament motor activity|negative regulation of myosin ATPase activity|down regulation of actin-dependent ATPase activity|negative regulation of actin-activated ATPase activity|negative regulation of actin-filament motor activity|inhibition of actin-activated ATPase activity|negative regulation of muscle motor activity|down regulation of actin-activated ATPase activity|negative regulation of actin-dependent ATPase activity|inhibition of actin-dependent ATPase activity http://purl.obolibrary.org/obo/GO_0120080 GO:0120081 biolink:BiologicalProcess positive regulation of microfilament motor activity Any process that activates or increases the frequency, rate or extent of microfilament motor activity. go.json positive regulation of myosin ATPase activity|activation of actin-activated ATPase activity|upregulation of actin-dependent ATPase activity|activation of actin-dependent ATPase activity|positive regulation of actin-activated ATPase activity|positive regulation of muscle motor activity|positive regulation of actin-filament motor activity|positive regulation of actin-dependent ATPase activity|positive regulation of actin filament motor activity http://purl.obolibrary.org/obo/GO_0120081 GO:0120017 biolink:MolecularActivity ceramide transfer activity Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go.json ceramide carrier activity|intermembrane ceramide transfer activity|ceramide transporter activity http://purl.obolibrary.org/obo/GO_0120017 GO:0120018 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0120018 GO:0120019 biolink:MolecularActivity phosphatidylcholine transfer activity Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go.json phosphatidylcholine carrier activity|intermembrane phosphatidylcholine transfer activity http://purl.obolibrary.org/obo/GO_0120019 GO:0120013 biolink:MolecularActivity lipid transfer activity Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids. go.json lipid carrier activity|intermembrane lipid transfer activity http://purl.obolibrary.org/obo/GO_0120013 GO:0120014 biolink:MolecularActivity phospholipid transfer activity Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go.json phospholipid carrier activity|intermembrane phospholipid transfer activity http://purl.obolibrary.org/obo/GO_0120014 GO:0120015 biolink:MolecularActivity sterol transfer activity Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go.json sterol carrier activity|intermembrane sterol transfer activity http://purl.obolibrary.org/obo/GO_0120015 GO:0120016 biolink:MolecularActivity sphingolipid transfer activity Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go.json sphingolipid carrier activity|intermembrane sphingolipid transfer activity http://purl.obolibrary.org/obo/GO_0120016 GO:0120010 biolink:BiologicalProcess intermembrane phospholipid transfer The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. go.json http://purl.obolibrary.org/obo/GO_0120010 GO:0120011 biolink:BiologicalProcess intermembrane sterol transfer The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). go.json http://purl.obolibrary.org/obo/GO_0120011 GO:0120012 biolink:BiologicalProcess intermembrane sphingolipid transfer The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). go.json http://purl.obolibrary.org/obo/GO_0120012 GO:0120028 biolink:BiologicalProcess negative regulation of osmosensory signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120028 GO:0120029 biolink:BiologicalProcess proton export across plasma membrane The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region. go.json proton export from cell|hydrogen ion export from cell|hydrogen ion export across plasma membrane|proton export across plasma membrane http://purl.obolibrary.org/obo/GO_0120029 GO:0120024 biolink:MolecularActivity glucagon-like peptide binding Interacting selectively and non-covalently with glucagon-like peptide, a antihyperglycemic hormone. Glucagon-like peptide is derived from the glucagon gene produced by pancreatic alpha cells. go.json http://purl.obolibrary.org/obo/GO_0120024 GO:0120025 biolink:CellularComponent plasma membrane bounded cell projection A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. go.json http://purl.obolibrary.org/obo/GO_0120025 GO:0120026 biolink:CellularComponent host cell uropod A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively. go.json host cell uropodium http://purl.obolibrary.org/obo/GO_0120026 GO:0120027 biolink:BiologicalProcess regulation of osmosensory signaling pathway Any process that modulates the frequency, rate or extent of osmosensory signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120027 GO:0120020 biolink:MolecularActivity cholesterol transfer activity Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Reactome:R-HSA-265443|Reactome:R-HSA-1454928|Reactome:R-HSA-5682111|Reactome:R-HSA-265545|Reactome:R-HSA-266082|Reactome:R-HSA-216723|Reactome:R-HSA-8951850 go.json cholesterol carrier activity|intermembrane cholesterol transfer activity|cholesterol transporter activity http://purl.obolibrary.org/obo/GO_0120020 GO:0120021 biolink:MolecularActivity oxysterol transfer activity Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go.json intermembrane oxysterol transfer activity|oxysterol carrier activity http://purl.obolibrary.org/obo/GO_0120021 GO:0120022 biolink:MolecularActivity glucagon binding Interacting selectively and non-covalently with glucagon, a polypeptide hormone involved in glucose response. It is produced by pancreatic alpha cells and raises the concentration of glucose in the blood. go.json http://purl.obolibrary.org/obo/GO_0120022 GO:0120023 biolink:MolecularActivity somatostatin binding Interacting selectively and non-covalently with somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin. go.json http://purl.obolibrary.org/obo/GO_0120023 GO:0120039 biolink:BiologicalProcess plasma membrane bounded cell projection morphogenesis The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. go.json http://purl.obolibrary.org/obo/GO_0120039 GO:0120035 biolink:BiologicalProcess regulation of plasma membrane bounded cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. go.json http://purl.obolibrary.org/obo/GO_0120035 GO:0120036 biolink:BiologicalProcess plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. go.json http://purl.obolibrary.org/obo/GO_0120036 GO:0120038 biolink:CellularComponent obsolete plasma membrane bounded cell projection part OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon. go.json http://purl.obolibrary.org/obo/GO_0120038 GO:0120031 biolink:BiologicalProcess plasma membrane bounded cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. go.json eupodium http://purl.obolibrary.org/obo/GO_0120031 GO:0120032 biolink:BiologicalProcess regulation of plasma membrane bounded cell projection assembly Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. go.json http://purl.obolibrary.org/obo/GO_0120032 GO:0120033 biolink:BiologicalProcess negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. go.json http://purl.obolibrary.org/obo/GO_0120033 GO:0120034 biolink:BiologicalProcess positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. go.json http://purl.obolibrary.org/obo/GO_0120034 GO:0120030 biolink:BiologicalProcess positive regulation of cilium beat frequency involved in ciliary motility Any process that activates or increases the frequency of cilium beating involved in ciliary motility. go.json http://purl.obolibrary.org/obo/GO_0120030 GO:0120046 biolink:BiologicalProcess regulation of protein localization to medial cortical node Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node. go.json http://purl.obolibrary.org/obo/GO_0120046 GO:0120047 biolink:BiologicalProcess positive regulation of protein localization to medial cortical node Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node. go.json http://purl.obolibrary.org/obo/GO_0120047 GO:0120048 biolink:MolecularActivity U6 snRNA (adenine-(43)-N(6))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA. go.json http://purl.obolibrary.org/obo/GO_0120048 GO:0120049 biolink:BiologicalProcess snRNA (adenine-N6)-methylation The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule. go.json http://purl.obolibrary.org/obo/GO_0120049 GO:0120042 biolink:BiologicalProcess negative regulation of macrophage proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation. go.json http://purl.obolibrary.org/obo/GO_0120042 GO:0120043 biolink:CellularComponent stereocilium shaft The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle. go.json http://purl.obolibrary.org/obo/GO_0120043 GO:0120044 biolink:CellularComponent stereocilium base The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium. go.json stereocilium taper http://purl.obolibrary.org/obo/GO_0120044 GO:0120045 biolink:BiologicalProcess stereocilium maintenance The organization process that preserves a stereocilium in a stable functional or structural state. go.json http://purl.obolibrary.org/obo/GO_0120045 GO:0120040 biolink:BiologicalProcess regulation of macrophage proliferation Any process that modulates the frequency, rate or extent of macrophage proliferation. go.json http://purl.obolibrary.org/obo/GO_0120040 GO:0120041 biolink:BiologicalProcess positive regulation of macrophage proliferation Any process that activates or increases the frequency, rate or extent of macrophage proliferation. go.json http://purl.obolibrary.org/obo/GO_0120041 GO:0002863 biolink:BiologicalProcess positive regulation of inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. go.json stimulation of inflammatory response to antigenic stimulus|upregulation of inflammatory response to antigenic stimulus|up-regulation of inflammatory response to antigenic stimulus|up regulation of inflammatory response to antigenic stimulus|activation of inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002863 GO:0002864 biolink:BiologicalProcess regulation of acute inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. go.json http://purl.obolibrary.org/obo/GO_0002864 GO:0002865 biolink:BiologicalProcess negative regulation of acute inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. go.json down regulation of acute inflammatory response to antigenic stimulus|inhibition of acute inflammatory response to antigenic stimulus|downregulation of acute inflammatory response to antigenic stimulus|down-regulation of acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002865 GO:0002866 biolink:BiologicalProcess positive regulation of acute inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. go.json up-regulation of acute inflammatory response to antigenic stimulus|up regulation of acute inflammatory response to antigenic stimulus|activation of acute inflammatory response to antigenic stimulus|stimulation of acute inflammatory response to antigenic stimulus|upregulation of acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002866 GO:0002860 biolink:BiologicalProcess positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. go.json upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target|up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|stimulation of natural killer cell mediated cytotoxicity directed against tumor cell target|activation of natural killer cell mediated cytotoxicity directed against tumor cell target|up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002860 GO:0002861 biolink:BiologicalProcess regulation of inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. go.json http://purl.obolibrary.org/obo/GO_0002861 GO:0002862 biolink:BiologicalProcess negative regulation of inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. go.json down-regulation of inflammatory response to antigenic stimulus|down regulation of inflammatory response to antigenic stimulus|inhibition of inflammatory response to antigenic stimulus|downregulation of inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002862 GO:0061160 biolink:BiologicalProcess regulation of establishment of bipolar cell polarity regulating cell shape Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell. go.json http://purl.obolibrary.org/obo/GO_0061160 GO:0061161 biolink:BiologicalProcess positive regulation of establishment of bipolar cell polarity regulating cell shape Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell. go.json http://purl.obolibrary.org/obo/GO_0061161 GO:0061162 biolink:BiologicalProcess establishment of monopolar cell polarity The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. go.json http://purl.obolibrary.org/obo/GO_0061162 GO:0061163 biolink:BiologicalProcess endoplasmic reticulum polarization The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity. go.json endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|ER polarization|maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site|transitional endoplasmic reticulum polarization at cell division site|ER localization involved in ER polarization at cell division site|endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|establishment of endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site http://purl.obolibrary.org/obo/GO_0061163 GO:0061164 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061164 GO:0061165 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061165 GO:0061166 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061166 GO:0061167 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0061167 GO:0061168 biolink:BiologicalProcess regulation of hair follicle placode formation Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. go.json http://purl.obolibrary.org/obo/GO_0061168 GO:0061169 biolink:BiologicalProcess positive regulation of hair placode formation Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. go.json http://purl.obolibrary.org/obo/GO_0061169 GO:0002867 biolink:BiologicalProcess regulation of B cell deletion Any process that modulates the frequency, rate, or extent of B cell deletion. go.json regulation of B lymphocyte deletion|regulation of B-cell deletion|regulation of B-lymphocyte deletion http://purl.obolibrary.org/obo/GO_0002867 GO:0002868 biolink:BiologicalProcess negative regulation of B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion. go.json down-regulation of B cell deletion|down regulation of B cell deletion|inhibition of B cell deletion|downregulation of B cell deletion|negative regulation of B-lymphocyte deletion|negative regulation of B lymphocyte deletion|negative regulation of B-cell deletion http://purl.obolibrary.org/obo/GO_0002868 GO:0002869 biolink:BiologicalProcess positive regulation of B cell deletion Any process that activates or increases the frequency, rate, or extent of B cell deletion. go.json stimulation of B cell deletion|upregulation of B cell deletion|positive regulation of B-lymphocyte deletion|up-regulation of B cell deletion|positive regulation of B lymphocyte deletion|positive regulation of B-cell deletion|up regulation of B cell deletion|activation of B cell deletion http://purl.obolibrary.org/obo/GO_0002869 GO:0002874 biolink:BiologicalProcess regulation of chronic inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. go.json http://purl.obolibrary.org/obo/GO_0002874 GO:0002875 biolink:BiologicalProcess negative regulation of chronic inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. go.json inhibition of chronic inflammatory response to antigenic stimulus|downregulation of chronic inflammatory response to antigenic stimulus|down-regulation of chronic inflammatory response to antigenic stimulus|down regulation of chronic inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002875 GO:0002876 biolink:BiologicalProcess positive regulation of chronic inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. go.json up-regulation of chronic inflammatory response to antigenic stimulus|up regulation of chronic inflammatory response to antigenic stimulus|activation of chronic inflammatory response to antigenic stimulus|stimulation of chronic inflammatory response to antigenic stimulus|upregulation of chronic inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002876 GO:0002877 biolink:BiologicalProcess regulation of acute inflammatory response to non-antigenic stimulus Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. go.json http://purl.obolibrary.org/obo/GO_0002877 GO:0002870 biolink:BiologicalProcess T cell anergy Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction. go.json T-lymphocyte anergy|T lymphocyte anergy|T-cell anergy http://purl.obolibrary.org/obo/GO_0002870 GO:0002871 biolink:BiologicalProcess regulation of natural killer cell tolerance induction Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction. go.json regulation of NK cell tolerance induction http://purl.obolibrary.org/obo/GO_0002871 GO:0002872 biolink:BiologicalProcess negative regulation of natural killer cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction. go.json down regulation of natural killer cell tolerance induction|inhibition of natural killer cell tolerance induction|downregulation of natural killer cell tolerance induction|negative regulation of NK cell tolerance induction|down-regulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002872 GO:0002873 biolink:BiologicalProcess positive regulation of natural killer cell tolerance induction Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction. go.json up-regulation of natural killer cell tolerance induction|positive regulation of NK cell tolerance induction|up regulation of natural killer cell tolerance induction|activation of natural killer cell tolerance induction|stimulation of natural killer cell tolerance induction|upregulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002873 GO:0061150 biolink:BiologicalProcess renal system segmentation The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis. go.json urinary tract segmentation http://purl.obolibrary.org/obo/GO_0061150 GO:0061151 biolink:BiologicalProcess BMP signaling pathway involved in renal system segmentation A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system. go.json BMP signalling pathway involved in renal system segmentation http://purl.obolibrary.org/obo/GO_0061151 GO:0061152 biolink:BiologicalProcess trachea submucosa development The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. go.json http://purl.obolibrary.org/obo/GO_0061152 GO:0061153 biolink:BiologicalProcess trachea gland development The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. go.json http://purl.obolibrary.org/obo/GO_0061153 GO:0061154 biolink:BiologicalProcess endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. go.json http://purl.obolibrary.org/obo/GO_0061154 GO:0061155 biolink:BiologicalProcess pulmonary artery endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. go.json http://purl.obolibrary.org/obo/GO_0061155 GO:0061156 biolink:BiologicalProcess pulmonary artery morphogenesis The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. go.json http://purl.obolibrary.org/obo/GO_0061156 GO:0061157 biolink:BiologicalProcess mRNA destabilization Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. go.json http://purl.obolibrary.org/obo/GO_0061157 GO:0061158 biolink:BiologicalProcess 3'-UTR-mediated mRNA destabilization An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. go.json http://purl.obolibrary.org/obo/GO_0061158 GO:0061159 biolink:BiologicalProcess establishment of bipolar cell polarity involved in cell morphogenesis The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane. go.json http://purl.obolibrary.org/obo/GO_0061159 GO:0002878 biolink:BiologicalProcess negative regulation of acute inflammatory response to non-antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. go.json down regulation of acute inflammatory response to non-antigenic stimulus|inhibition of acute inflammatory response to non-antigenic stimulus|downregulation of acute inflammatory response to non-antigenic stimulus|down-regulation of acute inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002878 GO:0002879 biolink:BiologicalProcess positive regulation of acute inflammatory response to non-antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. go.json up-regulation of acute inflammatory response to non-antigenic stimulus|up regulation of acute inflammatory response to non-antigenic stimulus|activation of acute inflammatory response to non-antigenic stimulus|stimulation of acute inflammatory response to non-antigenic stimulus|upregulation of acute inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002879 GO:0002841 biolink:BiologicalProcess negative regulation of T cell mediated immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell. go.json downregulation of T cell mediated immune response to tumor cell|negative regulation of T-lymphocyte mediated immune response to tumor cell|negative regulation of T lymphocyte mediated immune response to tumor cell|negative regulation of T cell mediated immune response to tumour cell|negative regulation of T-cell mediated immune response to tumor cell|down-regulation of T cell mediated immune response to tumor cell|down regulation of T cell mediated immune response to tumor cell|inhibition of T cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002841 GO:0002842 biolink:BiologicalProcess positive regulation of T cell mediated immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell. go.json up-regulation of T cell mediated immune response to tumor cell|positive regulation of T lymphocyte mediated immune response to tumor cell|positive regulation of T-cell mediated immune response to tumor cell|up regulation of T cell mediated immune response to tumor cell|activation of T cell mediated immune response to tumor cell|stimulation of T cell mediated immune response to tumor cell|upregulation of T cell mediated immune response to tumor cell|positive regulation of T cell mediated immune response to tumour cell|positive regulation of T-lymphocyte mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002842 GO:0002843 biolink:BiologicalProcess regulation of tolerance induction to tumor cell Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell. go.json regulation of tolerance induction to tumour cell http://purl.obolibrary.org/obo/GO_0002843 GO:0002844 biolink:BiologicalProcess negative regulation of tolerance induction to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell. go.json downregulation of tolerance induction to tumor cell|inhibition of tolerance induction to tumor cell|negative regulation of tolerance induction to tumour cell|down-regulation of tolerance induction to tumor cell|down regulation of tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002844 GO:0002840 biolink:BiologicalProcess regulation of T cell mediated immune response to tumor cell Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell. go.json regulation of T cell mediated immune response to tumour cell|regulation of T-lymphocyte mediated immune response to tumor cell|regulation of T lymphocyte mediated immune response to tumor cell|regulation of T-cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002840 GO:0061180 biolink:BiologicalProcess mammary gland epithelium development The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. go.json breast epithelium development http://purl.obolibrary.org/obo/GO_0061180 GO:0061181 biolink:BiologicalProcess regulation of chondrocyte development Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. go.json http://purl.obolibrary.org/obo/GO_0061181 GO:0061182 biolink:BiologicalProcess negative regulation of chondrocyte development Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. go.json http://purl.obolibrary.org/obo/GO_0061182 GO:0061183 biolink:BiologicalProcess regulation of dermatome development Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go.json http://purl.obolibrary.org/obo/GO_0061183 GO:0061184 biolink:BiologicalProcess positive regulation of dermatome development Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go.json http://purl.obolibrary.org/obo/GO_0061184 GO:0061185 biolink:BiologicalProcess negative regulation of dermatome development Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go.json http://purl.obolibrary.org/obo/GO_0061185 GO:0061186 biolink:BiologicalProcess negative regulation of silent mating-type cassette heterochromatin assembly Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. go.json negative regulation of chromatin silencing at silent mating-type cassette http://purl.obolibrary.org/obo/GO_0061186 GO:0061187 biolink:BiologicalProcess regulation of ribosomal DNA heterochromatin assembly Any process that modulates the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin. go.json regulation of chromatin silencing at rDNA http://purl.obolibrary.org/obo/GO_0061187 GO:0061188 biolink:BiologicalProcess negative regulation of ribosomal DNA heterochromatin assembly Any process that decreases the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin. go.json negative regulation of chromatin silencing at rDNA http://purl.obolibrary.org/obo/GO_0061188 GO:0061189 biolink:BiologicalProcess positive regulation of sclerotome development Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. go.json http://purl.obolibrary.org/obo/GO_0061189 GO:0002849 biolink:BiologicalProcess regulation of peripheral T cell tolerance induction Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction. go.json http://purl.obolibrary.org/obo/GO_0002849 GO:0002845 biolink:BiologicalProcess positive regulation of tolerance induction to tumor cell Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell. go.json up-regulation of tolerance induction to tumor cell|up regulation of tolerance induction to tumor cell|activation of tolerance induction to tumor cell|stimulation of tolerance induction to tumor cell|positive regulation of tolerance induction to tumour cell|upregulation of tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002845 GO:0002846 biolink:BiologicalProcess regulation of T cell tolerance induction to tumor cell Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell. go.json http://purl.obolibrary.org/obo/GO_0002846 GO:0002847 biolink:BiologicalProcess negative regulation of T cell tolerance induction to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell. go.json down regulation of T cell tolerance induction to tumor cell|inhibition of T cell tolerance induction to tumor cell|down-regulation of T cell tolerance induction to tumor cell|downregulation of T cell tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002847 GO:0002848 biolink:BiologicalProcess positive regulation of T cell tolerance induction to tumor cell Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell. go.json upregulation of T cell tolerance induction to tumor cell|up regulation of T cell tolerance induction to tumor cell|stimulation of T cell tolerance induction to tumor cell|up-regulation of T cell tolerance induction to tumor cell|activation of T cell tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002848 GO:0002852 biolink:BiologicalProcess regulation of T cell mediated cytotoxicity directed against tumor cell target Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. go.json http://purl.obolibrary.org/obo/GO_0002852 GO:0002853 biolink:BiologicalProcess negative regulation of T cell mediated cytotoxicity directed against tumor cell target Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. go.json down regulation of T cell mediated cytotoxicity directed against tumor cell target|inhibition of T cell mediated cytotoxicity directed against tumor cell target|downregulation of T cell mediated cytotoxicity directed against tumor cell target|down-regulation of T cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002853 GO:0002854 biolink:BiologicalProcess positive regulation of T cell mediated cytotoxicity directed against tumor cell target Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. go.json up-regulation of T cell mediated cytotoxicity directed against tumor cell target|up regulation of T cell mediated cytotoxicity directed against tumor cell target|activation of T cell mediated cytotoxicity directed against tumor cell target|stimulation of T cell mediated cytotoxicity directed against tumor cell target|upregulation of T cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002854 GO:0002855 biolink:BiologicalProcess regulation of natural killer cell mediated immune response to tumor cell Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. go.json http://purl.obolibrary.org/obo/GO_0002855 GO:0002850 biolink:BiologicalProcess negative regulation of peripheral T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction. go.json down regulation of peripheral T cell tolerance induction|inhibition of peripheral T cell tolerance induction|downregulation of peripheral T cell tolerance induction|down-regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002850 GO:0002851 biolink:BiologicalProcess positive regulation of peripheral T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction. go.json up-regulation of peripheral T cell tolerance induction|up regulation of peripheral T cell tolerance induction|activation of peripheral T cell tolerance induction|stimulation of peripheral T cell tolerance induction|upregulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002851 GO:0061170 biolink:BiologicalProcess negative regulation of hair follicle placode formation Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. go.json http://purl.obolibrary.org/obo/GO_0061170 GO:0061171 biolink:BiologicalProcess establishment of bipolar cell polarity The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane. go.json http://purl.obolibrary.org/obo/GO_0061171 GO:0061172 biolink:BiologicalProcess regulation of establishment of bipolar cell polarity Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane. go.json http://purl.obolibrary.org/obo/GO_0061172 GO:0061173 biolink:BiologicalProcess positive regulation of establishment of bipolar cell polarity Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity. go.json http://purl.obolibrary.org/obo/GO_0061173 GO:0061174 biolink:CellularComponent type I terminal bouton Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. go.json type I terminal button http://purl.obolibrary.org/obo/GO_0061174 GO:0061175 biolink:CellularComponent type II terminal bouton Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. go.json type II terminal button http://purl.obolibrary.org/obo/GO_0061175 GO:0061176 biolink:CellularComponent type Ib terminal bouton Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons. go.json type Ib terminal button http://purl.obolibrary.org/obo/GO_0061176 GO:0061177 biolink:CellularComponent type Is terminal bouton Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons. go.json type Is terminal button http://purl.obolibrary.org/obo/GO_0061177 GO:0061178 biolink:BiologicalProcess regulation of insulin secretion involved in cellular response to glucose stimulus Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. go.json regulation of insulin secretion in response to glucose http://purl.obolibrary.org/obo/GO_0061178 GO:0061179 biolink:BiologicalProcess negative regulation of insulin secretion involved in cellular response to glucose stimulus Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. go.json negative regulation of insulin secretion involved in cellular response to glucose|negative regulation of insulin secretion in response to glucose http://purl.obolibrary.org/obo/GO_0061179 GO:0002856 biolink:BiologicalProcess negative regulation of natural killer cell mediated immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. go.json downregulation of natural killer cell mediated immune response to tumor cell|down regulation of natural killer cell mediated immune response to tumor cell|inhibition of natural killer cell mediated immune response to tumor cell|down-regulation of natural killer cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002856 GO:0002857 biolink:BiologicalProcess positive regulation of natural killer cell mediated immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. go.json upregulation of natural killer cell mediated immune response to tumor cell|up regulation of natural killer cell mediated immune response to tumor cell|stimulation of natural killer cell mediated immune response to tumor cell|activation of natural killer cell mediated immune response to tumor cell|up-regulation of natural killer cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002857 GO:0002858 biolink:BiologicalProcess regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. go.json http://purl.obolibrary.org/obo/GO_0002858 GO:0002859 biolink:BiologicalProcess negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. go.json downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target|down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target|down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002859 GO:0002820 biolink:BiologicalProcess negative regulation of adaptive immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. go.json down regulation of adaptive immune response|inhibition of adaptive immune response|down-regulation of adaptive immune response|downregulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0002820 GO:0002821 biolink:BiologicalProcess positive regulation of adaptive immune response Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. go.json upregulation of adaptive immune response|stimulation of adaptive immune response|up regulation of adaptive immune response|up-regulation of adaptive immune response|activation of adaptive immune response http://purl.obolibrary.org/obo/GO_0002821 GO:0002822 biolink:BiologicalProcess regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. go.json http://purl.obolibrary.org/obo/GO_0002822 GO:0120097 biolink:CellularComponent glycosylphosphatidylinositol-mannosyltransferase II complex A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p. go.json GPI-MT-I complex http://purl.obolibrary.org/obo/GO_0120097 GO:0120098 biolink:CellularComponent procentriole A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells. go.json http://purl.obolibrary.org/obo/GO_0120098 GO:0120099 biolink:CellularComponent procentriole replication complex A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates. go.json http://purl.obolibrary.org/obo/GO_0120099 GO:0120093 biolink:BiologicalProcess regulation of peptidyl-lysine crotonylation Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein. go.json http://purl.obolibrary.org/obo/GO_0120093 GO:0002827 biolink:BiologicalProcess positive regulation of T-helper 1 type immune response Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response. go.json up regulation of T-helper 1 type immune response|activation of T-helper 1 type immune response|stimulation of T-helper 1 type immune response|upregulation of T-helper 1 type immune response|up-regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002827 GO:0120094 biolink:BiologicalProcess negative regulation of peptidyl-lysine crotonylation Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein. go.json http://purl.obolibrary.org/obo/GO_0120094 GO:0002828 biolink:BiologicalProcess regulation of type 2 immune response Any process that modulates the frequency, rate, or extent of a type 2 immune response. go.json regulation of T-helper 2 type immune response|regulation of Th2 immune response http://purl.obolibrary.org/obo/GO_0002828 GO:0002829 biolink:BiologicalProcess negative regulation of type 2 immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response. go.json inhibition of type 2 immune response|down-regulation of type 2 immune response|negative regulation of T-helper 2 type immune response|negative regulation of Th2 immune response|downregulation of type 2 immune response|down regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0002829 GO:0120095 biolink:CellularComponent vacuole-isolation membrane contact site An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome. go.json vacuole-phagophore contact site|vacuole-IM contact site|VICS http://purl.obolibrary.org/obo/GO_0120095 GO:0002823 biolink:BiologicalProcess negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. go.json http://purl.obolibrary.org/obo/GO_0002823 GO:0002824 biolink:BiologicalProcess positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. go.json http://purl.obolibrary.org/obo/GO_0002824 GO:0120091 biolink:MolecularActivity jasmonic acid hydrolase Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid. go.json 2-oxoglutarate dioxygenase http://purl.obolibrary.org/obo/GO_0120091 GO:0002825 biolink:BiologicalProcess regulation of T-helper 1 type immune response Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response. go.json http://purl.obolibrary.org/obo/GO_0002825 GO:0120092 biolink:MolecularActivity crotonyl-CoA hydratase activity Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. RHEA:45584 go.json http://purl.obolibrary.org/obo/GO_0120092 GO:0002826 biolink:BiologicalProcess negative regulation of T-helper 1 type immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response. go.json down-regulation of T-helper 1 type immune response|down regulation of T-helper 1 type immune response|inhibition of T-helper 1 type immune response|downregulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002826 GO:0002830 biolink:BiologicalProcess positive regulation of type 2 immune response Any process that activates or increases the frequency, rate, or extent of a type 2 immune response. go.json up regulation of type 2 immune response|stimulation of type 2 immune response|up-regulation of type 2 immune response|activation of type 2 immune response|positive regulation of T-helper 2 type immune response|upregulation of type 2 immune response|positive regulation of Th2 immune response http://purl.obolibrary.org/obo/GO_0002830 GO:0002831 biolink:BiologicalProcess regulation of response to biotic stimulus Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. go.json http://purl.obolibrary.org/obo/GO_0002831 gocheck_do_not_manually_annotate GO:0002832 biolink:BiologicalProcess negative regulation of response to biotic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. go.json down-regulation of response to biotic stimulus|down regulation of response to biotic stimulus|inhibition of response to biotic stimulus|downregulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0002832 gocheck_do_not_manually_annotate GO:0002833 biolink:BiologicalProcess positive regulation of response to biotic stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. go.json activation of response to biotic stimulus|stimulation of response to biotic stimulus|upregulation of response to biotic stimulus|up-regulation of response to biotic stimulus|up regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0002833 gocheck_do_not_manually_annotate GO:0061190 biolink:BiologicalProcess regulation of sclerotome development Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. go.json http://purl.obolibrary.org/obo/GO_0061190 GO:0061191 biolink:BiologicalProcess positive regulation of vacuole fusion, non-autophagic Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. go.json http://purl.obolibrary.org/obo/GO_0061191 GO:0061192 biolink:BiologicalProcess negative regulation of vacuole fusion, non-autophagic Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. go.json http://purl.obolibrary.org/obo/GO_0061192 GO:0061193 biolink:BiologicalProcess taste bud development The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. go.json http://purl.obolibrary.org/obo/GO_0061193 GO:0061194 biolink:BiologicalProcess taste bud morphogenesis The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. go.json http://purl.obolibrary.org/obo/GO_0061194 GO:0061195 biolink:BiologicalProcess taste bud formation The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. go.json http://purl.obolibrary.org/obo/GO_0061195 GO:0061196 biolink:BiologicalProcess fungiform papilla development The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue. go.json http://purl.obolibrary.org/obo/GO_0061196 GO:0061197 biolink:BiologicalProcess fungiform papilla morphogenesis The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue. go.json http://purl.obolibrary.org/obo/GO_0061197 GO:0061198 biolink:BiologicalProcess fungiform papilla formation The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue. go.json http://purl.obolibrary.org/obo/GO_0061198 GO:0061199 biolink:BiologicalProcess striated muscle contraction involved in embryonic body morphogenesis The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology. go.json http://purl.obolibrary.org/obo/GO_0061199 GO:0002838 biolink:BiologicalProcess negative regulation of immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell. go.json down regulation of immune response to tumor cell|inhibition of immune response to tumor cell|downregulation of immune response to tumor cell|negative regulation of immune response to tumour cell|down-regulation of immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002838 GO:0002839 biolink:BiologicalProcess positive regulation of immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell. go.json up-regulation of immune response to tumor cell|up regulation of immune response to tumor cell|activation of immune response to tumor cell|positive regulation of immune response to tumour cell|stimulation of immune response to tumor cell|upregulation of immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002839 GO:0002834 biolink:BiologicalProcess regulation of response to tumor cell Any process that modulates the frequency, rate, or extent of a response to tumor cell. go.json regulation of response to tumour cell http://purl.obolibrary.org/obo/GO_0002834 GO:0002835 biolink:BiologicalProcess negative regulation of response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell. go.json downregulation of response to tumor cell|negative regulation of response to tumour cell|down regulation of response to tumor cell|inhibition of response to tumor cell|down-regulation of response to tumor cell http://purl.obolibrary.org/obo/GO_0002835 GO:0002836 biolink:BiologicalProcess positive regulation of response to tumor cell Any process that activates or increases the frequency, rate, or extent of a response to tumor cell. go.json positive regulation of response to tumour cell|up regulation of response to tumor cell|stimulation of response to tumor cell|up-regulation of response to tumor cell|activation of response to tumor cell|upregulation of response to tumor cell http://purl.obolibrary.org/obo/GO_0002836 GO:0002837 biolink:BiologicalProcess regulation of immune response to tumor cell Any process that modulates the frequency, rate, or extent of an immune response to tumor cell. go.json regulation of immune response to tumour cell http://purl.obolibrary.org/obo/GO_0002837 GO:0002800 biolink:BiologicalProcess regulation of antifungal peptide secretion Any process that modulates the frequency, rate, or extent of antifungal peptide secretion. go.json http://purl.obolibrary.org/obo/GO_0002800 GO:0002809 biolink:BiologicalProcess negative regulation of antibacterial peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis. go.json downregulation of antibacterial peptide biosynthetic process|down regulation of antibacterial peptide biosynthetic process|inhibition of antibacterial peptide biosynthetic process|down-regulation of antibacterial peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002809 GO:0002805 biolink:BiologicalProcess regulation of antimicrobial peptide biosynthetic process Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis. go.json http://purl.obolibrary.org/obo/GO_0002805 GO:0002806 biolink:BiologicalProcess negative regulation of antimicrobial peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis. go.json downregulation of antimicrobial peptide biosynthetic process|down regulation of antimicrobial peptide biosynthetic process|inhibition of antimicrobial peptide biosynthetic process|down-regulation of antimicrobial peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002806 GO:0002807 biolink:BiologicalProcess positive regulation of antimicrobial peptide biosynthetic process Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis. go.json up-regulation of antimicrobial peptide biosynthetic process|activation of antimicrobial peptide biosynthetic process|upregulation of antimicrobial peptide biosynthetic process|up regulation of antimicrobial peptide biosynthetic process|stimulation of antimicrobial peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002807 GO:0002808 biolink:BiologicalProcess regulation of antibacterial peptide biosynthetic process Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis. go.json http://purl.obolibrary.org/obo/GO_0002808 OBO:go#systematic_synonym biolink:OntologyClass Systematic synonym go.json http://purl.obolibrary.org/obo/go#systematic_synonym GO:0002801 biolink:BiologicalProcess negative regulation of antifungal peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion. go.json downregulation of antifungal peptide secretion|down regulation of antifungal peptide secretion|inhibition of antifungal peptide secretion|down-regulation of antifungal peptide secretion http://purl.obolibrary.org/obo/GO_0002801 GO:0002802 biolink:BiologicalProcess positive regulation of antifungal peptide secretion Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion. go.json up regulation of antifungal peptide secretion|stimulation of antifungal peptide secretion|activation of antifungal peptide secretion|up-regulation of antifungal peptide secretion|upregulation of antifungal peptide secretion http://purl.obolibrary.org/obo/GO_0002802 GO:0002803 biolink:BiologicalProcess positive regulation of antibacterial peptide production Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production. go.json stimulation of antibacterial peptide production|up-regulation of antibacterial peptide production|activation of antibacterial peptide production|upregulation of antibacterial peptide production|up regulation of antibacterial peptide production http://purl.obolibrary.org/obo/GO_0002803 GO:0002804 biolink:BiologicalProcess positive regulation of antifungal peptide production Any process that activates or increases the frequency, rate, or extent of antifungal peptide production. go.json up regulation of antifungal peptide production|activation of antifungal peptide production|stimulation of antifungal peptide production|upregulation of antifungal peptide production|up-regulation of antifungal peptide production http://purl.obolibrary.org/obo/GO_0002804 GO:0002810 biolink:BiologicalProcess regulation of antifungal peptide biosynthetic process Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis. go.json http://purl.obolibrary.org/obo/GO_0002810 GO:0002811 biolink:BiologicalProcess negative regulation of antifungal peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis. go.json down-regulation of antifungal peptide biosynthetic process|down regulation of antifungal peptide biosynthetic process|inhibition of antifungal peptide biosynthetic process|downregulation of antifungal peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002811 GO:0002816 biolink:BiologicalProcess regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. go.json http://purl.obolibrary.org/obo/GO_0002816 GO:0002817 biolink:BiologicalProcess negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. go.json downregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|down regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|down-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria http://purl.obolibrary.org/obo/GO_0002817 GO:0002818 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002818 GO:0002819 biolink:BiologicalProcess regulation of adaptive immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response. go.json http://purl.obolibrary.org/obo/GO_0002819 GO:0002812 biolink:BiologicalProcess biosynthetic process of antibacterial peptides active against Gram-negative bacteria The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria. go.json http://purl.obolibrary.org/obo/GO_0002812 GO:0002813 biolink:BiologicalProcess regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. go.json http://purl.obolibrary.org/obo/GO_0002813 GO:0002814 biolink:BiologicalProcess negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. go.json down regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|down-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria http://purl.obolibrary.org/obo/GO_0002814 GO:0002815 biolink:BiologicalProcess biosynthetic process of antibacterial peptides active against Gram-positive bacteria The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria. go.json http://purl.obolibrary.org/obo/GO_0002815 GO:0075720 biolink:BiologicalProcess establishment of episomal latency A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity. go.json establishment as a plasmid prophage|establishment of plasmid latency http://purl.obolibrary.org/obo/GO_0075720 GO:0051753 biolink:MolecularActivity mannan synthase activity Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan. go.json galactomannan beta-1,4-mannosyltransferase activity|mannan beta-1,4-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0051753 GO:0051754 biolink:BiologicalProcess meiotic sister chromatid cohesion, centromeric The cell cycle process in which centromeres of sister chromatids are joined during meiosis. go.json centromeric meiotic sister chromatin cohesion|meiotic sister chromatid cohesion at centromere|sister chromatid cohesion at centromere at meiosis I http://purl.obolibrary.org/obo/GO_0051754 GO:0051751 biolink:MolecularActivity alpha-1,4-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage. go.json http://purl.obolibrary.org/obo/GO_0051751 GO:0051752 biolink:MolecularActivity phosphoglucan, water dikinase activity Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate. MetaCyc:2.7.9.5-RXN|EC:2.7.9.5 go.json PWD|ATP:phospho-alpha-glucan, water phosphotransferase activity|OK1 http://purl.obolibrary.org/obo/GO_0051752 GO:0051757 biolink:BiologicalProcess meiotic sister chromatid separation The process in which sister chromatids are physically detached from each other during meiosis. go.json meiotic sister chromatid resolution http://purl.obolibrary.org/obo/GO_0051757 GO:0051758 biolink:BiologicalProcess homologous chromosome movement towards spindle pole in meiosis I anaphase The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase. go.json meiosis I, homologous chromosome movement towards spindle pole|homologous chromosome movement towards spindle pole during meiosis I http://purl.obolibrary.org/obo/GO_0051758 GO:0051755 biolink:BiologicalProcess meiotic sister chromatid arm separation The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis. go.json http://purl.obolibrary.org/obo/GO_0051755 GO:0051756 biolink:BiologicalProcess meiotic sister chromatid centromere separation The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis. go.json http://purl.obolibrary.org/obo/GO_0051756 GO:0051759 biolink:BiologicalProcess sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II. go.json sister chromosome movement towards spindle pole during meiosis II|meiosis II, sister chromosome movement towards spindle pole http://purl.obolibrary.org/obo/GO_0051759 GO:0036112 biolink:BiologicalProcess medium-chain fatty-acyl-CoA metabolic process The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. go.json medium-chain fatty acyl-CoA metabolism|medium-chain fatty acyl CoA metabolic process http://purl.obolibrary.org/obo/GO_0036112 GO:0036113 biolink:BiologicalProcess very long-chain fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. go.json very long-chain fatty-acyl-CoA breakdown|very long-chain fatty-acyl-CoA catabolism|very long-chain fatty-acyl-CoA degradation http://purl.obolibrary.org/obo/GO_0036113 GO:0036114 biolink:BiologicalProcess medium-chain fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. go.json medium-chain fatty-acyl-CoA breakdown|medium-chain fatty-acyl-CoA catabolism|medium-chain fatty-acyl-CoA degradation http://purl.obolibrary.org/obo/GO_0036114 GO:0036115 biolink:BiologicalProcess fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. go.json fatty-acyl-CoA catabolism|fatty-acyl-CoA degradation|fatty-acyl-CoA breakdown http://purl.obolibrary.org/obo/GO_0036115 GO:0036116 biolink:BiologicalProcess long-chain fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go.json long-chain fatty-acyl-CoA catabolism|long-chain fatty-acyl-CoA degradation|long-chain fatty-acyl-CoA breakdown http://purl.obolibrary.org/obo/GO_0036116 GO:0036117 biolink:CellularComponent hyaluranon cable A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan. go.json HA cable http://purl.obolibrary.org/obo/GO_0036117 GO:0036118 biolink:BiologicalProcess hyaluranon cable assembly A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan. go.json HA cable assembly http://purl.obolibrary.org/obo/GO_0036118 GO:0036119 biolink:BiologicalProcess response to platelet-derived growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus. go.json response to PDGF stimulus|response to platelet-derived growth factor stimulus http://purl.obolibrary.org/obo/GO_0036119 GO:0051750 biolink:MolecularActivity delta3,5-delta2,4-dienoyl-CoA isomerase activity Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA. go.json delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase activity|delta5-delta2,4-dienoyl-CoA isomerase activity http://purl.obolibrary.org/obo/GO_0051750 GO:0036110 biolink:BiologicalProcess cellular response to inositol starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol. go.json http://purl.obolibrary.org/obo/GO_0036110 GO:0036111 biolink:BiologicalProcess very long-chain fatty-acyl-CoA metabolic process The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. go.json very long-chain fatty acyl CoA metabolic process|very long-chain fatty acyl-CoA metabolism http://purl.obolibrary.org/obo/GO_0036111 GO:0051764 biolink:BiologicalProcess actin crosslink formation The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes. go.json formation of actin crosslink|actin bundling|actin crosslinking|bridging actin filaments http://purl.obolibrary.org/obo/GO_0051764 GO:0075710 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075710 GO:0051765 biolink:MolecularActivity inositol tetrakisphosphate kinase activity Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP. go.json http://purl.obolibrary.org/obo/GO_0051765 GO:0051762 biolink:BiologicalProcess sesquiterpene biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. go.json http://purl.obolibrary.org/obo/GO_0051762 GO:0051763 biolink:BiologicalProcess sesquiterpene catabolic process The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. go.json http://purl.obolibrary.org/obo/GO_0051763 GO:0075713 biolink:BiologicalProcess establishment of integrated proviral latency A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage. VZ:980 go.json prophage integration|provirus integration http://purl.obolibrary.org/obo/GO_0075713 GO:0051768 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051768 GO:0051769 biolink:BiologicalProcess regulation of nitric-oxide synthase biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme. go.json regulation of nitric-oxide synthase (type 2) biosynthetic process|regulation of nitric-oxide synthase (type 2) biosynthesis|regulation of nitric-oxide synthase (type II) biosynthetic process|regulation of nitric-oxide synthase (type II) biosynthesis|regulation of NO synthase biosynthetic process|regulation of NO synthase biosynthesis|regulation of nitric-oxide synthase 2 biosynthetic process|regulation of NOS biosynthetic process|regulation of NOS2 synthase biosynthetic process|regulation of NOS2 synthase biosynthesis|regulation of NOS biosynthesis http://purl.obolibrary.org/obo/GO_0051769 GO:0051766 biolink:MolecularActivity inositol trisphosphate kinase activity Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP. go.json http://purl.obolibrary.org/obo/GO_0051766 GO:0051767 biolink:BiologicalProcess nitric-oxide synthase biosynthetic process The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. go.json endothelial nitric-oxide synthase biosynthetic process|nitric-oxide synthase-2 biosynthetic process|NOS2 synthase biosynthesis|nitric-oxide synthase-3 biosynthetic process|NOS2 synthase biosynthetic process|brain nitric-oxide synthase biosynthetic process|NOS biosynthesis|NOS biosynthetic process|NO synthase biosynthesis|NO synthase biosynthetic process|nitric-oxide synthase (type II) biosynthesis|nitric-oxide synthase (type II) biosynthetic process|inducible nitric-oxide synthase biosynthetic process|NOS1 biosynthesis|NOS2 biosynthesis|nitric-oxide synthase 2 biosynthetic process|NOS3 biosynthesis|nitric-oxide synthase (type 2) biosynthetic process|nitric-oxide synthase-1 biosynthetic process|nitric-oxide synthase (type 2) biosynthesis http://purl.obolibrary.org/obo/GO_0051767 GO:0075716 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075716 GO:0036109 biolink:BiologicalProcess alpha-linolenic acid metabolic process The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. Wikipedia:Linoleic_acid go.json alpha-linolenic acid metabolism|ALA metabolism http://purl.obolibrary.org/obo/GO_0036109 GO:0075717 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075717 GO:0036101 biolink:BiologicalProcess leukotriene B4 catabolic process The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. go.json leukotriene B4 breakdown|leukotriene B4 catabolism|leukotriene B4 degradation|LTB4 catabolism http://purl.obolibrary.org/obo/GO_0036101 GO:0036102 biolink:BiologicalProcess leukotriene B4 metabolic process The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. go.json LTB4 metabolism http://purl.obolibrary.org/obo/GO_0036102 GO:0036103 biolink:BiologicalProcess Kdo2-lipid A metabolic process The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component. go.json Kdo2-lipid A metabolism http://purl.obolibrary.org/obo/GO_0036103 GO:0036104 biolink:BiologicalProcess Kdo2-lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component. go.json Kdo2-lipid A anabolism|Kdo2-lipid A synthesis|Kdo2-lipid A formation|Kdo2-lipid A biosynthesis|di[3-deoxy-D-manno-octulosonyl]-lipid A biosynthesis|KDO(2)-lipid A biosynthesis http://purl.obolibrary.org/obo/GO_0036104 GO:0036105 biolink:MolecularActivity peroxisome membrane class-1 targeting sequence binding Interacting selectively and non-covalently with a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner. go.json PEX19-dependent mPTS binding|class 1 mPTS binding http://purl.obolibrary.org/obo/GO_0036105 GO:0036106 biolink:MolecularActivity peroxisome membrane class-2 targeting sequence binding Interacting selectively and non-covalently with a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner. go.json PEX19-independent mPTS binding|class 2 mPTS binding http://purl.obolibrary.org/obo/GO_0036106 GO:0036107 biolink:BiologicalProcess 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). go.json 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process|undecaprenyl phosphate alpha-L-Ara4N metabolism http://purl.obolibrary.org/obo/GO_0036107 GO:0036108 biolink:BiologicalProcess 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). go.json 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate anabolism|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate synthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate formation|undecaprenyl phosphate alpha-L-Ara4N biosynthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0036108 GO:0051760 biolink:BiologicalProcess meiotic sister chromatid cohesion, arms The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis. go.json sister chromatid cohesion along arms at meiosis I|meiotic sister chromatid cohesion along arms http://purl.obolibrary.org/obo/GO_0051760 GO:0099703 biolink:BiologicalProcess induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission. go.json http://purl.obolibrary.org/obo/GO_0099703 goslim_synapse GO:0051761 biolink:BiologicalProcess sesquiterpene metabolic process The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. go.json sesquiterpene metabolism http://purl.obolibrary.org/obo/GO_0051761 GO:0036100 biolink:BiologicalProcess leukotriene catabolic process The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. go.json leukotriene breakdown|leukotriene catabolism|leukotriene degradation http://purl.obolibrary.org/obo/GO_0036100 GO:0051775 biolink:BiologicalProcess response to redox state Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. go.json redox signal response http://purl.obolibrary.org/obo/GO_0051775 GO:0051776 biolink:BiologicalProcess detection of redox state The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. go.json redox sensing http://purl.obolibrary.org/obo/GO_0051776 GO:0051773 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051773 GO:0051774 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051774 GO:0051779 biolink:MolecularActivity gibberellin 12-aldehyde oxidase activity Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). RHEA:22700|MetaCyc:RXN1F-161 go.json GA12-aldehyde oxidase activity http://purl.obolibrary.org/obo/GO_0051779 GO:0051777 biolink:MolecularActivity ent-kaurenoate oxidase activity Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). RHEA:19241|MetaCyc:1.14.13.79-RXN go.json ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity|ent-kaurenoic acid oxidase activity http://purl.obolibrary.org/obo/GO_0051777 GO:0051778 biolink:MolecularActivity ent-7-alpha-hydroxykaurenoate oxidase activity Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). MetaCyc:RXN1F-160|RHEA:22904 go.json http://purl.obolibrary.org/obo/GO_0051778 GO:0061100 biolink:BiologicalProcess lung neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. go.json http://purl.obolibrary.org/obo/GO_0061100 GO:0061101 biolink:BiologicalProcess neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. go.json http://purl.obolibrary.org/obo/GO_0061101 GO:0061102 biolink:BiologicalProcess stomach neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium. go.json gastric neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061102 GO:0061103 biolink:BiologicalProcess carotid body glomus cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia. go.json http://purl.obolibrary.org/obo/GO_0061103 GO:0061104 biolink:BiologicalProcess adrenal chromaffin cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. go.json http://purl.obolibrary.org/obo/GO_0061104 GO:0061105 biolink:BiologicalProcess regulation of stomach neuroendocrine cell differentiation Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. go.json http://purl.obolibrary.org/obo/GO_0061105 GO:0061106 biolink:BiologicalProcess negative regulation of stomach neuroendocrine cell differentiation Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. go.json http://purl.obolibrary.org/obo/GO_0061106 GO:0061107 biolink:BiologicalProcess seminal vesicle development The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. go.json http://purl.obolibrary.org/obo/GO_0061107 GO:0061108 biolink:BiologicalProcess seminal vesicle epithelium development The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061108 GO:0061109 biolink:BiologicalProcess dense core granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. go.json dense core granule organisation http://purl.obolibrary.org/obo/GO_0061109 GO:0051771 biolink:BiologicalProcess negative regulation of nitric-oxide synthase biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme. go.json negative regulation of nitric-oxide synthase (type II) biosynthesis|downregulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase (type II) biosynthetic process|negative regulation of NO synthase biosynthetic process|negative regulation of NO synthase biosynthesis|downregulation of nitric-oxide synthase biosynthetic process|down regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthesis|down-regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase 2 biosynthetic process|down regulation of nitric-oxide synthase biosynthetic process|inhibition of nitric-oxide synthase biosynthetic process|inhibition of nitric-oxide synthase 2 biosynthetic process|down-regulation of nitric-oxide synthase biosynthetic process|negative regulation of NOS2 synthase biosynthesis|negative regulation of NOS2 synthase biosynthetic process|negative regulation of NOS biosynthesis|negative regulation of NOS biosynthetic process http://purl.obolibrary.org/obo/GO_0051771 GO:0051772 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051772 GO:0051770 biolink:BiologicalProcess positive regulation of nitric-oxide synthase biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme. go.json positive regulation of NOS2 synthase biosynthetic process|positive regulation of NOS biosynthesis|positive regulation of NOS2 synthase biosynthesis|up regulation of nitric-oxide synthase biosynthetic process|positive regulation of NOS biosynthetic process|up-regulation of nitric-oxide synthase 2 biosynthetic process|stimulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase (type 2) biosynthesis|positive regulation of nitric-oxide synthase (type 2) biosynthetic process|up-regulation of nitric-oxide synthase biosynthetic process|stimulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NO synthase biosynthetic process|positive regulation of nitric-oxide synthase (type II) biosynthesis|positive regulation of NO synthase biosynthesis|activation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase (type II) biosynthetic process|activation of nitric-oxide synthase 2 biosynthetic process|upregulation of nitric-oxide synthase 2 biosynthetic process|upregulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase 2 biosynthetic process|up regulation of nitric-oxide synthase 2 biosynthetic process http://purl.obolibrary.org/obo/GO_0051770 GO:0051786 biolink:MolecularActivity all-trans-retinol 13,14-reductase activity Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction. KEGG_REACTION:R07163|MetaCyc:1.3.99.23-RXN|Reactome:R-HSA-8956427|EC:1.3.99.23|RHEA:19193 go.json retinol saturase activity|all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity|RetSat activity|all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity|(13,14)-all-trans-retinol saturase activity http://purl.obolibrary.org/obo/GO_0051786 GO:0051787 biolink:MolecularActivity misfolded protein binding Interacting selectively and non-covalently with a misfolded protein. Reactome:R-HSA-5324632 go.json http://purl.obolibrary.org/obo/GO_0051787 GO:0075732 biolink:BiologicalProcess viral penetration into host nucleus The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid. VZ:989 go.json viral entry into host nucleus|viral import into host nucleus http://purl.obolibrary.org/obo/GO_0075732 GO:0051784 biolink:BiologicalProcess negative regulation of nuclear division Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. go.json inhibition of nuclear division|down-regulation of nuclear division|downregulation of nuclear division|down regulation of nuclear division http://purl.obolibrary.org/obo/GO_0051784 GO:0075733 biolink:BiologicalProcess intracellular transport of virus The directed movement of a virus, or part of a virus, within the host cell. go.json viral genome transport in host cell|egress of virus within host cell|viral egress|intracellular virion transport|intracellular transport of viral material|movement of virus within host cell http://purl.obolibrary.org/obo/GO_0075733 GO:0051785 biolink:BiologicalProcess positive regulation of nuclear division Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. go.json upregulation of nuclear division|stimulation of nuclear division|up regulation of nuclear division|up-regulation of nuclear division|activation of nuclear division http://purl.obolibrary.org/obo/GO_0051785 GO:0051788 biolink:BiologicalProcess response to misfolded protein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus. go.json http://purl.obolibrary.org/obo/GO_0051788 GO:0051789 biolink:BiologicalProcess obsolete response to protein OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. go.json response to protein stimulus|response to protein http://purl.obolibrary.org/obo/GO_0051789 GO:0051782 biolink:BiologicalProcess negative regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. go.json down-regulation of cell division|down regulation of cell division|inhibition of cell division|downregulation of cell division http://purl.obolibrary.org/obo/GO_0051782 GO:0051783 biolink:BiologicalProcess regulation of nuclear division Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. go.json http://purl.obolibrary.org/obo/GO_0051783 GO:0051780 biolink:BiologicalProcess behavioral response to nutrient Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus. go.json behavioural response to nutrient http://purl.obolibrary.org/obo/GO_0051780 GO:0051781 biolink:BiologicalProcess positive regulation of cell division Any process that activates or increases the frequency, rate or extent of cell division. go.json up regulation of cell division|activation of cell division|stimulation of cell division|upregulation of cell division|up-regulation of cell division http://purl.obolibrary.org/obo/GO_0051781 GO:0051797 biolink:BiologicalProcess regulation of hair follicle development Any process that modulates the frequency, rate or extent of hair follicle development. go.json http://purl.obolibrary.org/obo/GO_0051797 GO:0002786 biolink:BiologicalProcess regulation of antibacterial peptide production Any process that modulates the frequency, rate, or extent of antibacterial peptide production. go.json http://purl.obolibrary.org/obo/GO_0002786 GO:0002787 biolink:BiologicalProcess negative regulation of antibacterial peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production. go.json downregulation of antibacterial peptide production|down regulation of antibacterial peptide production|inhibition of antibacterial peptide production|down-regulation of antibacterial peptide production http://purl.obolibrary.org/obo/GO_0002787 GO:0051798 biolink:BiologicalProcess positive regulation of hair follicle development Any process that activates or increases the frequency, rate or extent of hair follicle development. go.json up-regulation of hair follicle development|up regulation of hair follicle development|activation of hair follicle development|stimulation of hair follicle development|upregulation of hair follicle development http://purl.obolibrary.org/obo/GO_0051798 GO:0002788 biolink:BiologicalProcess regulation of antifungal peptide production Any process that modulates the frequency, rate, or extent of antifungal peptide production. go.json http://purl.obolibrary.org/obo/GO_0002788 GO:0051795 biolink:BiologicalProcess positive regulation of timing of catagen Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. go.json upregulation of catagen|activation of catagen|up-regulation of catagen|stimulation of catagen|up regulation of catagen|positive regulation of catagen http://purl.obolibrary.org/obo/GO_0051795 GO:0051796 biolink:BiologicalProcess negative regulation of timing of catagen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. go.json down-regulation of catagen|negative regulation of catagen|inhibition of catagen|down regulation of catagen|downregulation of catagen http://purl.obolibrary.org/obo/GO_0051796 GO:0002789 biolink:BiologicalProcess negative regulation of antifungal peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production. go.json down-regulation of antifungal peptide production|down regulation of antifungal peptide production|inhibition of antifungal peptide production|downregulation of antifungal peptide production http://purl.obolibrary.org/obo/GO_0002789 GO:0002782 biolink:BiologicalProcess antifungal peptide secretion The regulated release of an antifungal peptide from a cell or a tissue. go.json http://purl.obolibrary.org/obo/GO_0002782 GO:0002783 biolink:BiologicalProcess antifungal peptide biosynthetic process The chemical reactions and pathways resulting in the formation of an antifungal peptide. go.json http://purl.obolibrary.org/obo/GO_0002783 GO:0051799 biolink:BiologicalProcess negative regulation of hair follicle development Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development. go.json down-regulation of hair follicle development|down regulation of hair follicle development|inhibition of hair follicle development|downregulation of hair follicle development http://purl.obolibrary.org/obo/GO_0051799 GO:0002784 biolink:BiologicalProcess regulation of antimicrobial peptide production Any process that modulates the frequency, rate, or extent of antimicrobial peptide production. go.json http://purl.obolibrary.org/obo/GO_0002784 GO:0002785 biolink:BiologicalProcess negative regulation of antimicrobial peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production. go.json down regulation of antimicrobial peptide production|inhibition of antimicrobial peptide production|down-regulation of antimicrobial peptide production|downregulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002785 GO:0002780 biolink:BiologicalProcess antibacterial peptide biosynthetic process The chemical reactions and pathways resulting in the formation of an antibacterial peptide. go.json http://purl.obolibrary.org/obo/GO_0002780 GO:0002781 biolink:BiologicalProcess antifungal peptide production The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels. go.json http://purl.obolibrary.org/obo/GO_0002781 gocheck_do_not_annotate GO:0061120 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP by DIF-1 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. go.json http://purl.obolibrary.org/obo/GO_0061120 GO:0061121 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP by DIF-2 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. go.json http://purl.obolibrary.org/obo/GO_0061121 GO:0061122 biolink:BiologicalProcess positive regulation of positive chemotaxis to cAMP Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. go.json http://purl.obolibrary.org/obo/GO_0061122 GO:0061123 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. go.json http://purl.obolibrary.org/obo/GO_0061123 GO:0061124 biolink:BiologicalProcess positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. go.json http://purl.obolibrary.org/obo/GO_0061124 GO:0061125 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. go.json http://purl.obolibrary.org/obo/GO_0061125 GO:0061126 biolink:BiologicalProcess positive regulation of positive chemotaxis to cAMP by DIF-1 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. go.json http://purl.obolibrary.org/obo/GO_0061126 GO:0061127 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP by DIF-1 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. go.json http://purl.obolibrary.org/obo/GO_0061127 GO:0061128 biolink:BiologicalProcess positive regulation of chemotaxis to cAMP by DIF-2 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. go.json http://purl.obolibrary.org/obo/GO_0061128 GO:0061129 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP by DIF-2 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. go.json http://purl.obolibrary.org/obo/GO_0061129 GO:0051790 biolink:BiologicalProcess short-chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6. go.json short-chain fatty acid synthesis|short-chain fatty acid formation|short-chain fatty acid biosynthesis|short chain fatty acid biosynthesis|short chain fatty acid biosynthetic process|short-chain fatty acid anabolism http://purl.obolibrary.org/obo/GO_0051790 GO:0099738 biolink:CellularComponent cell cortex region The complete extent of cell cortex that underlies some some region of the plasma membrane. go.json perimembrane region http://purl.obolibrary.org/obo/GO_0099738 GO:0051793 biolink:BiologicalProcess medium-chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of any fatty acid with a chain length of between C6 and C12. go.json medium-chain fatty acid degradation|medium-chain fatty acid catabolism|medium-chain fatty acid breakdown|medium chain fatty acid catabolism|medium chain fatty acid catabolic process http://purl.obolibrary.org/obo/GO_0051793 GO:0051794 biolink:BiologicalProcess regulation of timing of catagen Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. go.json regulation of catagen http://purl.obolibrary.org/obo/GO_0051794 GO:0051791 biolink:BiologicalProcess medium-chain fatty acid metabolic process The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12. go.json medium-chain fatty acid metabolism|medium chain fatty acid metabolism|medium chain fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0051791 GO:0051792 biolink:BiologicalProcess medium-chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12. go.json medium chain fatty acid biosynthetic process|medium chain fatty acid biosynthesis|medium-chain fatty acid anabolism|medium-chain fatty acid synthesis|medium-chain fatty acid formation|medium-chain fatty acid biosynthesis http://purl.obolibrary.org/obo/GO_0051792 GO:0002797 biolink:BiologicalProcess regulation of antibacterial peptide secretion Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion. go.json http://purl.obolibrary.org/obo/GO_0002797 GO:0002798 biolink:BiologicalProcess negative regulation of antibacterial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion. go.json down-regulation of antibacterial peptide secretion|down regulation of antibacterial peptide secretion|inhibition of antibacterial peptide secretion|downregulation of antibacterial peptide secretion http://purl.obolibrary.org/obo/GO_0002798 GO:0002799 biolink:BiologicalProcess positive regulation of antibacterial peptide secretion Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion. go.json up regulation of antibacterial peptide secretion|activation of antibacterial peptide secretion|stimulation of antibacterial peptide secretion|upregulation of antibacterial peptide secretion|up-regulation of antibacterial peptide secretion http://purl.obolibrary.org/obo/GO_0002799 GO:0002793 biolink:BiologicalProcess positive regulation of peptide secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. go.json up-regulation of peptide secretion|up regulation of peptide secretion|activation of peptide secretion|stimulation of peptide secretion|upregulation of peptide secretion http://purl.obolibrary.org/obo/GO_0002793 GO:0002794 biolink:BiologicalProcess regulation of antimicrobial peptide secretion Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion. go.json http://purl.obolibrary.org/obo/GO_0002794 GO:0002795 biolink:BiologicalProcess negative regulation of antimicrobial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion. go.json down-regulation of antimicrobial peptide secretion|down regulation of antimicrobial peptide secretion|downregulation of antimicrobial peptide secretion|inhibition of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002795 GO:0002796 biolink:BiologicalProcess positive regulation of antimicrobial peptide secretion Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion. go.json up regulation of antimicrobial peptide secretion|activation of antimicrobial peptide secretion|stimulation of antimicrobial peptide secretion|upregulation of antimicrobial peptide secretion|up-regulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002796 GO:0002790 biolink:BiologicalProcess peptide secretion The controlled release of a peptide from a cell or a tissue. go.json http://purl.obolibrary.org/obo/GO_0002790 GO:0002791 biolink:BiologicalProcess regulation of peptide secretion Any process that modulates the frequency, rate, or extent of peptide secretion. go.json http://purl.obolibrary.org/obo/GO_0002791 GO:0002792 biolink:BiologicalProcess negative regulation of peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. go.json downregulation of peptide secretion|down-regulation of peptide secretion|down regulation of peptide secretion|inhibition of peptide secretion http://purl.obolibrary.org/obo/GO_0002792 GO:0061110 biolink:BiologicalProcess dense core granule biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule. go.json http://purl.obolibrary.org/obo/GO_0061110 GO:0061111 biolink:BiologicalProcess epithelial-mesenchymal cell signaling involved in lung development Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ. go.json epithelial-mesenchymal cell signalling involved in lung development http://purl.obolibrary.org/obo/GO_0061111 GO:0061112 biolink:BiologicalProcess negative regulation of bud outgrowth involved in lung branching Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching. go.json http://purl.obolibrary.org/obo/GO_0061112 GO:0061113 biolink:BiologicalProcess pancreas morphogenesis Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. go.json http://purl.obolibrary.org/obo/GO_0061113 GO:0061114 biolink:BiologicalProcess branching involved in pancreas morphogenesis The process in which the branches of the pancreas are generated and organized. go.json http://purl.obolibrary.org/obo/GO_0061114 GO:0061115 biolink:BiologicalProcess lung proximal/distal axis specification The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli. go.json http://purl.obolibrary.org/obo/GO_0061115 GO:0061116 biolink:BiologicalProcess ductus venosus closure The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth. go.json http://purl.obolibrary.org/obo/GO_0061116 GO:0061117 biolink:BiologicalProcess negative regulation of heart growth Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. go.json http://purl.obolibrary.org/obo/GO_0061117 GO:0061118 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. go.json http://purl.obolibrary.org/obo/GO_0061118 GO:0061119 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP by chlorinated alkylphenone Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. go.json http://purl.obolibrary.org/obo/GO_0061119 GO:0002764 biolink:BiologicalProcess immune response-regulating signaling pathway The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response. go.json immune response-regulating signalling pathway http://purl.obolibrary.org/obo/GO_0002764 GO:0002765 biolink:BiologicalProcess immune response-inhibiting signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response. go.json http://purl.obolibrary.org/obo/GO_0002765 GO:0002766 biolink:BiologicalProcess innate immune response-inhibiting signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response. go.json http://purl.obolibrary.org/obo/GO_0002766 GO:0002767 biolink:BiologicalProcess immune response-inhibiting cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response. go.json immune response-inhibiting cell surface receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002767 GO:0002760 biolink:BiologicalProcess positive regulation of antimicrobial humoral response Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response. go.json up regulation of antimicrobial humoral response|stimulation of antimicrobial humoral response|up-regulation of antimicrobial humoral response|activation of antimicrobial humoral response|upregulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0002760 GO:0002761 biolink:BiologicalProcess regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. go.json http://purl.obolibrary.org/obo/GO_0002761 GO:0002762 biolink:BiologicalProcess negative regulation of myeloid leukocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. go.json down-regulation of myeloid leukocyte differentiation|down regulation of myeloid leukocyte differentiation|inhibition of myeloid leukocyte differentiation|downregulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0002762 GO:0002763 biolink:BiologicalProcess positive regulation of myeloid leukocyte differentiation Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. go.json activation of myeloid leukocyte differentiation|stimulation of myeloid leukocyte differentiation|upregulation of myeloid leukocyte differentiation|up-regulation of myeloid leukocyte differentiation|up regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0002763 GO:0061140 biolink:BiologicalProcess lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. go.json http://purl.obolibrary.org/obo/GO_0061140 GO:0061141 biolink:BiologicalProcess lung ciliated cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells. go.json http://purl.obolibrary.org/obo/GO_0061141 GO:0061142 biolink:BiologicalProcess mesothelial-mesenchymal cell signaling involved in early lung development Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung. go.json mesothelial-mesenchymal cell signalling involved in early lung development http://purl.obolibrary.org/obo/GO_0061142 GO:0061143 biolink:BiologicalProcess alveolar primary septum development The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms. go.json http://purl.obolibrary.org/obo/GO_0061143 GO:0061144 biolink:BiologicalProcess alveolar secondary septum development The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule. go.json http://purl.obolibrary.org/obo/GO_0061144 GO:0061145 biolink:BiologicalProcess lung smooth muscle development The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061145 GO:0061146 biolink:BiologicalProcess Peyer's patch morphogenesis The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. go.json http://purl.obolibrary.org/obo/GO_0061146 GO:0061147 biolink:BiologicalProcess endocardial endothelium development The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. go.json http://purl.obolibrary.org/obo/GO_0061147 GO:0061148 biolink:BiologicalProcess extracellular matrix organization involved in endocardium development A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. go.json extracellular matrix organisation involved in endocardium development http://purl.obolibrary.org/obo/GO_0061148 GO:0061149 biolink:BiologicalProcess BMP signaling pathway involved in ureter morphogenesis A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder. go.json BMP signalling pathway involved in ureter morphogenesis http://purl.obolibrary.org/obo/GO_0061149 GO:0002768 biolink:BiologicalProcess immune response-regulating cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response. go.json immune response-regulating cell surface receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002768 GO:0002769 biolink:BiologicalProcess natural killer cell inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response. go.json inhibitory KIR signaling pathway|natural killer cell inhibitory signalling pathway|killer cell inhibitory receptor signaling pathway|NK cell inhibitory signaling pathway|Ly49 inhibitory receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002769 GO:0002775 biolink:BiologicalProcess antimicrobial peptide production The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. go.json http://purl.obolibrary.org/obo/GO_0002775 gocheck_do_not_annotate GO:0002776 biolink:BiologicalProcess antimicrobial peptide secretion The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. go.json http://purl.obolibrary.org/obo/GO_0002776 GO:0002777 biolink:BiologicalProcess antimicrobial peptide biosynthetic process The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. go.json http://purl.obolibrary.org/obo/GO_0002777 GO:0002778 biolink:BiologicalProcess antibacterial peptide production The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. go.json http://purl.obolibrary.org/obo/GO_0002778 gocheck_do_not_annotate GO:0002771 biolink:BiologicalProcess inhibitory killer cell immunoglobulin-like receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response. go.json inhibitory killer cell immunoglobulin-like receptor signalling pathway|killer cell inhibitory receptor signaling pathway|KIR signaling pathway http://purl.obolibrary.org/obo/GO_0002771 GO:0002772 biolink:BiologicalProcess inhibitory C-type lectin receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response. go.json inhibitory C-type lectin receptor signalling pathway|Ly49 inhibitory receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002772 GO:0002773 biolink:BiologicalProcess B cell inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response. go.json B-cell inhibitory signaling pathway|B lymphocyte inhibitory signaling pathwayBT-lymphocyte inhibitory signaling pathway|B cell inhibitory signalling pathway http://purl.obolibrary.org/obo/GO_0002773 GO:0002774 biolink:BiologicalProcess Fc receptor mediated inhibitory signaling pathway A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. go.json Fc receptor mediated inhibitory signalling pathway|Fc-receptor mediated inhibitory signaling pathway http://purl.obolibrary.org/obo/GO_0002774 GO:0002770 biolink:BiologicalProcess T cell inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response. go.json T cell inhibitory signalling pathway|T-lymphocyte inhibitory signaling pathway|T lymphocyte inhibitory signaling pathway|T-cell inhibitory signaling pathway http://purl.obolibrary.org/obo/GO_0002770 GO:0061130 biolink:BiologicalProcess pancreatic bud formation The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. go.json http://purl.obolibrary.org/obo/GO_0061130 GO:0061131 biolink:BiologicalProcess pancreas field specification The process in which a specific region of the gut is delineated into the area in which the pancreas will develop. go.json http://purl.obolibrary.org/obo/GO_0061131 GO:0061132 biolink:BiologicalProcess pancreas induction The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas. go.json http://purl.obolibrary.org/obo/GO_0061132 GO:0061133 biolink:MolecularActivity endopeptidase activator activity Binds to and increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. go.json http://purl.obolibrary.org/obo/GO_0061133 GO:0061134 biolink:MolecularActivity peptidase regulator activity Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. go.json http://purl.obolibrary.org/obo/GO_0061134 GO:0061135 biolink:MolecularActivity endopeptidase regulator activity Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. go.json http://purl.obolibrary.org/obo/GO_0061135 GO:0061136 biolink:BiologicalProcess regulation of proteasomal protein catabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. go.json http://purl.obolibrary.org/obo/GO_0061136 GO:0061137 biolink:BiologicalProcess bud dilation The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch. go.json http://purl.obolibrary.org/obo/GO_0061137 GO:0061138 biolink:BiologicalProcess morphogenesis of a branching epithelium The process in which the anatomical structures of a branched epithelium are generated and organized. go.json http://purl.obolibrary.org/obo/GO_0061138 GO:0061139 biolink:BiologicalProcess bud field specification The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go.json http://purl.obolibrary.org/obo/GO_0061139 GO:0002779 biolink:BiologicalProcess antibacterial peptide secretion The regulated release of an antibacterial peptide from a cell or a tissue. go.json http://purl.obolibrary.org/obo/GO_0002779 GO:0036192 biolink:MolecularActivity 3-hydroxyindolin-2-one monooxygenase activity Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O. EC:1.14.14.109|RHEA:31927|KEGG_REACTION:R07422 go.json 3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming) http://purl.obolibrary.org/obo/GO_0036192 GO:0036193 biolink:MolecularActivity 2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O. RHEA:31939|KEGG_REACTION:R07423|EC:1.14.14.110 go.json http://purl.obolibrary.org/obo/GO_0036193 GO:0036194 biolink:CellularComponent muscle cell projection A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. go.json muscle arm|myopodia|myocyte projection http://purl.obolibrary.org/obo/GO_0036194 GO:0036195 biolink:CellularComponent muscle cell projection membrane The portion of the plasma membrane surrounding a muscle cell projection. go.json http://purl.obolibrary.org/obo/GO_0036195 GO:0036196 biolink:BiologicalProcess zymosterol metabolic process The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol). go.json http://purl.obolibrary.org/obo/GO_0036196 GO:0036197 biolink:BiologicalProcess zymosterol biosynthetic process The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol). MetaCyc:PWY-6074|UniPathway:UPA00770 go.json zymosterol anabolism|zymosterol synthesis|zymosterol biosynthesis|zymosterol formation http://purl.obolibrary.org/obo/GO_0036197 GO:0036198 biolink:BiologicalProcess dTMP salvage Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis. UniPathway:UPA00578 go.json dTMP biosynthesis via salvage pathway|deoxythymidine monophosphate biosynthesis via salvage pathway http://purl.obolibrary.org/obo/GO_0036198 GO:0036199 biolink:MolecularActivity cholest-4-en-3-one 26-monooxygenase activity Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate. RHEA:51564|EC:1.14.15.29|KEGG_REACTION:R09859 go.json http://purl.obolibrary.org/obo/GO_0036199 GO:0036190 biolink:MolecularActivity indole-2-monooxygenase activity Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O. KEGG_REACTION:R07403|EC:1.14.14.153|RHEA:31899 go.json http://purl.obolibrary.org/obo/GO_0036190 GO:0036191 biolink:MolecularActivity indolin-2-one monooxygenase activity Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O. RHEA:31919|EC:1.14.14.157|KEGG_REACTION:R07421 go.json indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating) http://purl.obolibrary.org/obo/GO_0036191 GO:0120109 biolink:BiologicalProcess mitotic telomere clustering and tethering at nuclear periphery The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle. go.json http://purl.obolibrary.org/obo/GO_0120109 GO:0120105 biolink:CellularComponent mitotic actomyosin contractile ring, intermediate layer The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer. go.json actomyosin contractile ring, intermediate layer http://purl.obolibrary.org/obo/GO_0120105 GO:0120106 biolink:CellularComponent mitotic actomyosin contractile ring, distal actin filament layer The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to. go.json actomyosin contractile ring, distal actin filament layer http://purl.obolibrary.org/obo/GO_0120106 GO:0120107 biolink:CellularComponent bacterial-type flagellum rotor complex The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation. go.json http://purl.obolibrary.org/obo/GO_0120107 GO:0120108 biolink:MolecularActivity DNA-3'-diphospho-5'-guanosine diphosphatase Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H(2)O <=> (DNA)-3'-phosphate + GMP. RHEA:52140|EC:3.6.1.72 go.json DNA-3'pp5'G guanylate hydrolase http://purl.obolibrary.org/obo/GO_0120108 GO:0036189 biolink:MolecularActivity abieta-7,13-diene hydroxylase activity Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O. KEGG_REACTION:R06351|RHEA:26217|MetaCyc:RXN-8507|EC:1.14.14.144 go.json abietadiene hydroxylase http://purl.obolibrary.org/obo/GO_0036189 GO:0120101 biolink:CellularComponent bacterial-type flagellum stator complex A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. go.json bacterial-type flagellum torque generator complex|bacterial-type flagellum motor force generator complex http://purl.obolibrary.org/obo/GO_0120101 GO:0120102 biolink:CellularComponent bacterial-type flagellum secretion apparatus A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament. go.json bacterial-type flagellum export apparatus http://purl.obolibrary.org/obo/GO_0120102 GO:0120103 biolink:CellularComponent centriolar subdistal appendage A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68. go.json subdistal appendage of mother centriole|subdistal appendage of centriole|subdistal appendage of basal body http://purl.obolibrary.org/obo/GO_0120103 GO:0120104 biolink:CellularComponent mitotic actomyosin contractile ring, proximal layer The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located. go.json actomyosin contractile ring, proximal layer http://purl.obolibrary.org/obo/GO_0120104 GO:0120100 biolink:CellularComponent bacterial-type flagellum motor A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation. go.json http://purl.obolibrary.org/obo/GO_0120100 GO:0036181 biolink:BiologicalProcess protein localization to linear element A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase. go.json protein localisation to linear element http://purl.obolibrary.org/obo/GO_0036181 GO:0036182 biolink:BiologicalProcess asperthecin metabolic process The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. go.json asperthecin metabolism http://purl.obolibrary.org/obo/GO_0036182 GO:0036183 biolink:BiologicalProcess asperthecin catabolic process The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. go.json asperthecin breakdown|asperthecin catabolism|asperthecin degradation http://purl.obolibrary.org/obo/GO_0036183 GO:0036184 biolink:BiologicalProcess asperthecin biosynthetic process The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. go.json asperthecin synthesis|asperthecin formation|asperthecin biosynthesis http://purl.obolibrary.org/obo/GO_0036184 GO:0036185 biolink:MolecularActivity 13-lipoxin reductase activity Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+. Reactome:R-HSA-2161844 go.json http://purl.obolibrary.org/obo/GO_0036185 GO:0036186 biolink:CellularComponent early phagosome membrane The lipid bilayer surrounding an early phagosome. go.json early phagocytic vesicle membrane http://purl.obolibrary.org/obo/GO_0036186 GO:0036187 biolink:BiologicalProcess cell growth mode switching, budding to filamentous The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans. go.json yeast to hyphal transition http://purl.obolibrary.org/obo/GO_0036187 GO:0036188 biolink:MolecularActivity abieta-7,13-dien-18-al dehydrogenase activity Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+. MetaCyc:1.2.1.74-RXN|EC:1.2.1.74|KEGG_REACTION:R06357|RHEA:26225 go.json abietadienal dehydrogenase http://purl.obolibrary.org/obo/GO_0036188 GO:0036180 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to biotic stimulus The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus. go.json http://purl.obolibrary.org/obo/GO_0036180 GO:0120116 biolink:BiologicalProcess glucagon processing The formation of mature glucagon by proteolysis of the precursor proglucagon. go.json http://purl.obolibrary.org/obo/GO_0120116 GO:0120117 biolink:BiologicalProcess T cell meandering migration The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs). go.json T cell meandering search|lymph node surveillance http://purl.obolibrary.org/obo/GO_0120117 GO:0120118 biolink:CellularComponent flagella connector A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum. go.json http://purl.obolibrary.org/obo/GO_0120118 GO:0120119 biolink:CellularComponent flagellum attachment zone A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species. go.json FAZ http://purl.obolibrary.org/obo/GO_0120119 GO:0120112 biolink:BiologicalProcess UDP-glucose transmembrane transport into endoplasmic reticulum The directed movement of UDP-glucose from cytosol to endoplasmic reticulum. go.json http://purl.obolibrary.org/obo/GO_0120112 GO:0036178 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to neutral pH The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus. go.json http://purl.obolibrary.org/obo/GO_0036178 GO:0120113 biolink:BiologicalProcess cytoplasm to vacuole transport by the NVT pathway A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe. go.json cytoplasm to vacuole targeting|cytoplasm-to-vacuole targeting|protein localization by the Nbr1-mediated vacuolar targeting pathway|protein localization by the NVT pathway http://purl.obolibrary.org/obo/GO_0120113 GO:0036179 biolink:BiologicalProcess osteoclast maturation A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes. go.json chondroclast maturation http://purl.obolibrary.org/obo/GO_0036179 GO:0120114 biolink:CellularComponent Sm-like protein family complex A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles. go.json http://purl.obolibrary.org/obo/GO_0120114 GO:0120115 biolink:CellularComponent Lsm2-8 complex A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus. go.json http://purl.obolibrary.org/obo/GO_0120115 GO:0120110 biolink:BiologicalProcess interphase mitotic telomere clustering The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope. go.json mitotic telomere clustering during interphase http://purl.obolibrary.org/obo/GO_0120110 GO:0120111 biolink:CellularComponent neuron projection cytoplasm All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. go.json http://purl.obolibrary.org/obo/GO_0120111 GO:0036170 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to starvation The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment. go.json http://purl.obolibrary.org/obo/GO_0036170 GO:0036171 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to chemical stimulus The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus. go.json http://purl.obolibrary.org/obo/GO_0036171 GO:0036172 biolink:BiologicalProcess thiamine salvage A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis. MetaCyc:PWY-6898|MetaCyc:PWY-6897|MetaCyc:PWY-6896 go.json http://purl.obolibrary.org/obo/GO_0036172 GO:0036173 biolink:MolecularActivity thiosulfate binding Interacting selectively and non-covalently with the inorganic anion thiosulfate, a sulfur oxide that has formula O3S2. go.json http://purl.obolibrary.org/obo/GO_0036173 GO:0036174 biolink:MolecularActivity butane monooxygenase activity Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O. go.json sBMO|soluble butane monooxygenase http://purl.obolibrary.org/obo/GO_0036174 GO:0036175 biolink:MolecularActivity ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin. Reactome:R-HSA-111742|Reactome:R-HSA-8866405 go.json http://purl.obolibrary.org/obo/GO_0036175 GO:0036176 biolink:BiologicalProcess response to neutral pH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go.json http://purl.obolibrary.org/obo/GO_0036176 GO:0036177 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to pH The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go.json http://purl.obolibrary.org/obo/GO_0036177 GO:0051702 biolink:BiologicalProcess biological process involved in interaction with symbiont An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. go.json interaction with symbiont http://purl.obolibrary.org/obo/GO_0051702 GO:0051703 biolink:BiologicalProcess biological process involved in intraspecies interaction between organisms Any process in which an organism has an effect on an organism of the same species. go.json intraspecies interaction between organisms|intraspecies interaction with other organisms http://purl.obolibrary.org/obo/GO_0051703 gocheck_do_not_annotate|goslim_pir GO:0051700 biolink:MolecularActivity fructosyl-amino acid oxidase activity Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2. go.json FAOD activity http://purl.obolibrary.org/obo/GO_0051700 GO:0051701 biolink:BiologicalProcess biological process involved in interaction with host An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. go.json interaction with host|growth of symbiont in host organelle|growth of symbiont in host|growth of symbiont in host cell|growth of symbiont in host vacuole http://purl.obolibrary.org/obo/GO_0051701 GO:0051706 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051706 GO:0051707 biolink:BiologicalProcess response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. go.json http://purl.obolibrary.org/obo/GO_0051707 GO:0051704 biolink:BiologicalProcess multi-organism process A biological process which involves another organism of the same or different species. go.json physiological interaction with other organism|physiological interaction between organisms|interaction between organisms http://purl.obolibrary.org/obo/GO_0051704 gocheck_do_not_annotate|goslim_pir GO:0051705 biolink:BiologicalProcess obsolete multi-organism behavior OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species. go.json behavioural interaction with other organism|behavioural interaction between organisms|behavioral signalling|behavioral signaling|behavioral interaction with other organism|behavioral interaction between organisms http://purl.obolibrary.org/obo/GO_0051705 goslim_pir GO:0120127 biolink:BiologicalProcess response to zinc ion starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion. go.json http://purl.obolibrary.org/obo/GO_0120127 GO:0051708 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051708 GO:0051709 biolink:BiologicalProcess regulation of killing of cells of other organism Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism. go.json modulation by organism of apoptotic process in other organism involved in symbiotic interaction|regulation of killing of cells of another organism|modulation of programmed cell death in other organism|modulation of programmed cell death in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051709 GO:0120123 biolink:CellularComponent ubiquitin activating enzyme complex A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. go.json E1 complex|E1 ubiquitin-activating enzyme http://purl.obolibrary.org/obo/GO_0120123 GO:0036167 biolink:BiologicalProcess phenotypic switching in response to host A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. go.json http://purl.obolibrary.org/obo/GO_0036167 GO:0036168 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to heat The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature. go.json http://purl.obolibrary.org/obo/GO_0036168 GO:0120124 biolink:CellularComponent membrane fusion priming complex A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes. go.json GATE-16 complex|LMA1 complex http://purl.obolibrary.org/obo/GO_0120124 GO:0120125 biolink:CellularComponent PNGase complex A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue. go.json http://purl.obolibrary.org/obo/GO_0120125 GO:0036169 biolink:MolecularActivity 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2. Reactome:R-HSA-2162195 go.json http://purl.obolibrary.org/obo/GO_0036169 GO:0120126 biolink:BiologicalProcess response to copper ion starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion. go.json http://purl.obolibrary.org/obo/GO_0120126 GO:0120120 biolink:CellularComponent bilobe structure A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone). go.json kinetoplastid flagellar hook complex http://purl.obolibrary.org/obo/GO_0120120 GO:0120121 biolink:CellularComponent tripartite attachment complex A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body. go.json TAC http://purl.obolibrary.org/obo/GO_0120121 GO:0120122 biolink:BiologicalProcess prolactin metabolic process The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals. go.json prolactin metabolism http://purl.obolibrary.org/obo/GO_0120122 GO:0036160 biolink:BiologicalProcess melanocyte-stimulating hormone secretion The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation. go.json MSH secretion http://purl.obolibrary.org/obo/GO_0036160 GO:0036161 biolink:BiologicalProcess calcitonin secretion The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell. go.json http://purl.obolibrary.org/obo/GO_0036161 GO:0036162 biolink:BiologicalProcess oxytocin secretion The regulated release of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain, from a cell. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. go.json http://purl.obolibrary.org/obo/GO_0036162 GO:0036163 biolink:MolecularActivity 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2. RHEA:44768|KEGG_REACTION:R06866 go.json http://purl.obolibrary.org/obo/GO_0036163 GO:0036164 biolink:BiologicalProcess cell-abiotic substrate adhesion The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules. go.json cell-abiotic surface adhesion http://purl.obolibrary.org/obo/GO_0036164 GO:0036165 biolink:BiologicalProcess invasive growth in response to heat The growth of colonies in filamentous chains of cells as a result of an increase in temperature. go.json invasive growth in response to high temperature|invasive growth in response to elevated temperature|invasive growth in response to temperature stimulus http://purl.obolibrary.org/obo/GO_0036165 GO:0036166 biolink:BiologicalProcess phenotypic switching A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues. go.json phenotypic dimorphism http://purl.obolibrary.org/obo/GO_0036166 GO:0051710 biolink:BiologicalProcess regulation of cytolysis in other organism Any process that modulates the frequency, rate or extent of the cytolysis by an organism of cells in another organism. go.json regulation of cytolysis of cells of another, non-host, organism|regulation of cytolysis of cells of another organism http://purl.obolibrary.org/obo/GO_0051710 GO:0051713 biolink:BiologicalProcess negative regulation of cytolysis in other organism Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cytolysis of cells in another organism. go.json down regulation of cytolysis of cells of another organism|inhibition of cytolysis of cells of another organism|down-regulation of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another, non-host, organism|downregulation of cytolysis of cells of another organism http://purl.obolibrary.org/obo/GO_0051713 GO:0051714 biolink:BiologicalProcess positive regulation of cytolysis in other organism Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism. go.json positive regulation of cytolysis of cells of another, non-host, organism|upregulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another organism|stimulation of cytolysis of cells of another organism|up regulation of cytolysis of cells of another organism|activation of cytolysis of cells of another organism|up-regulation of cytolysis of cells of another organism http://purl.obolibrary.org/obo/GO_0051714 GO:0051711 biolink:BiologicalProcess negative regulation of killing of cells of other organism Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism. go.json downregulation of killing of cells of another organism|down regulation of killing of cells of another organism|inhibition of killing of cells of another organism|down-regulation of killing of cells of another organism|negative regulation of killing of cells of another organism|negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051711 GO:0051712 biolink:BiologicalProcess positive regulation of killing of cells of other organism Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism. go.json activation of killing of cells of another organism|up-regulation of killing of cells of another organism|positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction|enhancement of other organism programmed cell death by organism|upregulation of killing of cells of another organism|positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction|activation by organism of apoptotic programmed cell death in other organism during symbiotic interaction|induction by organism of apoptosis in other organism involved in symbiotic interaction|induction by organism of apoptosis in other organism during symbiotic interaction|stimulation of killing of cells of another organism|up regulation of killing of cells of another organism http://purl.obolibrary.org/obo/GO_0051712 GO:0051717 biolink:MolecularActivity inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate. Reactome:R-HSA-1855200|Reactome:R-HSA-1855205|MetaCyc:3.1.3.62-RXN go.json inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity|inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity|inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity http://purl.obolibrary.org/obo/GO_0051717 GO:0051718 biolink:MolecularActivity DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA). Reactome:R-HSA-5334151 go.json HpaII' methylase|HpaII methylase|M.BsuRIb|M.BsuRIa http://purl.obolibrary.org/obo/GO_0051718 GO:0051715 biolink:BiologicalProcess cytolysis in other organism The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm. go.json cytolysis of cells of another organism|cytolysis of cells of another, non-host, organism|cytolysis of cells of competing organism http://purl.obolibrary.org/obo/GO_0051715 GO:0051716 biolink:BiologicalProcess cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. go.json http://purl.obolibrary.org/obo/GO_0051716 gocheck_do_not_manually_annotate GO:0051719 biolink:MolecularActivity DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN. Reactome:R-HSA-5334152|Reactome:R-HSA-5334097 go.json http://purl.obolibrary.org/obo/GO_0051719 GO:0036156 biolink:CellularComponent inner dynein arm Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. go.json inner dynein arm complex http://purl.obolibrary.org/obo/GO_0036156 GO:0036157 biolink:CellularComponent outer dynein arm Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. go.json outer dynein arm complex http://purl.obolibrary.org/obo/GO_0036157 GO:0036158 biolink:BiologicalProcess outer dynein arm assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. go.json ODA assembly http://purl.obolibrary.org/obo/GO_0036158 GO:0036159 biolink:BiologicalProcess inner dynein arm assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. go.json IDA assembly http://purl.obolibrary.org/obo/GO_0036159 GO:0036150 biolink:BiologicalProcess phosphatidylserine acyl-chain remodeling Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains. go.json phosphatidyl-L-serine acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036150 GO:0036151 biolink:BiologicalProcess phosphatidylcholine acyl-chain remodeling Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains. go.json http://purl.obolibrary.org/obo/GO_0036151 GO:0036152 biolink:BiologicalProcess phosphatidylethanolamine acyl-chain remodeling Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains. go.json http://purl.obolibrary.org/obo/GO_0036152 GO:0036153 biolink:BiologicalProcess triglyceride acyl-chain remodeling Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains. go.json triacylglycerol acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036153 GO:0036154 biolink:BiologicalProcess diacylglycerol acyl-chain remodeling Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains. go.json diglyceride acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036154 GO:0036155 biolink:BiologicalProcess acylglycerol acyl-chain remodeling Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains. go.json glyceride acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036155 GO:0051720 biolink:MolecularActivity DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG. go.json http://purl.obolibrary.org/obo/GO_0051720 GO:0051721 biolink:MolecularActivity protein phosphatase 2A binding Interacting selectively and non-covalently with the enzyme protein phosphatase 2A. go.json protein phosphatase 2 binding http://purl.obolibrary.org/obo/GO_0051721 GO:0051724 biolink:MolecularActivity NAD transmembrane transporter activity Enables the transfer of NAD from one side of a membrane to the other. go.json NADH transporter activity|NAD+ transporter activity|NAD (oxidized) transporter activity|reduced nicotinamide adenine dinucleotide transmembrane transporter activity|reduced NAD transporter activity|nicotinamide adenine dinucleotide transmembrane transporter activity|oxidized nicotinamide adenine dinucleotide transmembrane transporter activity|NAD (reduced) transporter activity|oxidized NAD transporter activity|NAD transporter activity http://purl.obolibrary.org/obo/GO_0051724 GO:0051725 biolink:BiologicalProcess protein de-ADP-ribosylation The process of removing one or more ADP-ribose residues from a protein. go.json removal of ADP-ribose from protein|protein poly(ADP-ribose) catabolic process|protein poly(ADP-ribose) hydrolysis|protein poly(ADP-ribose) catabolism|protein amino acid de-ADP-ribosylation|poly(ADP-ribose) removal from protein|protein poly(ADP-ribose) degradation http://purl.obolibrary.org/obo/GO_0051725 GO:0051722 biolink:MolecularActivity protein C-terminal methylesterase activity Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol. Reactome:R-HSA-8856951 go.json protein phosphatase methylesterase activity http://purl.obolibrary.org/obo/GO_0051722 GO:0051723 biolink:MolecularActivity protein methylesterase activity Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol. Reactome:R-HSA-5367022 go.json protein methyl-esterase activity|protein carboxylic ester hydrolase activity|protein carboxyl methylesterase activity|PME activity http://purl.obolibrary.org/obo/GO_0051723 GO:0051728 biolink:BiologicalProcess cell cycle switching, mitotic to meiotic cell cycle The process in which a cell switches cell cycle mode from mitotic to meiotic division. go.json cell cycle switching, mitosis to meiosis|conversion to meiotic cell cycle|entry into meiosis|initiation of meiosis|initiation of meiotic cell cycle|conversion to meiosis|entry into meiotic cell cycle|meiotic entry http://purl.obolibrary.org/obo/GO_0051728 GO:0051729 biolink:BiologicalProcess germline cell cycle switching, mitotic to meiotic cell cycle The process in which a germline cell switches cell cycle mode from mitotic to meiotic division. go.json germline meiotic entry|germline initiation of meiotic cell cycle|germline initiation of meiosis|germline entry into meiotic cell cycle|germline cell cycle switching, mitosis to meiosis|germline conversion to meiosis|germline conversion to meiotic cell cycle|germline entry into meiosis http://purl.obolibrary.org/obo/GO_0051729 GO:0051726 biolink:BiologicalProcess regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle. go.json cell cycle arrest|cell cycle regulation|regulation of cell cycle arrest|arrest of mitotic cell cycle progression|regulation of progression through cell cycle|mitotic cell cycle arrest|positive regulation of cell cycle arrest|control of cell cycle progression|modulation of cell cycle progression|regulation of cell cycle progression|negative regulation of cell cycle arrest|cell cycle regulator|cell cycle modulation|tumor suppressor http://purl.obolibrary.org/obo/GO_0051726 goslim_yeast GO:0051727 biolink:BiologicalProcess obsolete cell cycle switching, meiotic to mitotic cell cycle OBSOLETE. The process in which a cell switches cell cycle mode from meiotic to mitotic division. go.json entry into mitotic cell cycle|cell cycle switching, meiosis to mitosis|conversion to mitosis|mitotic entry|cell cycle switching, meiotic to mitotic cell cycle|conversion to mitotic cell cycle|entry into mitosis|initiation of mitosis|initiation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0051727 GO:0036145 biolink:BiologicalProcess dendritic cell homeostasis The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. go.json DC homeostasis http://purl.obolibrary.org/obo/GO_0036145 GO:0036146 biolink:BiologicalProcess cellular response to mycotoxin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi. go.json http://purl.obolibrary.org/obo/GO_0036146 GO:0036147 biolink:BiologicalProcess rumination A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again. go.json digestive rumination http://purl.obolibrary.org/obo/GO_0036147 GO:0036148 biolink:BiologicalProcess phosphatidylglycerol acyl-chain remodeling Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains. go.json http://purl.obolibrary.org/obo/GO_0036148 GO:0036149 biolink:BiologicalProcess phosphatidylinositol acyl-chain remodeling Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains. go.json http://purl.obolibrary.org/obo/GO_0036149 GO:0036140 biolink:MolecularActivity peptidyl-asparagine 3-dioxygenase activity Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2. go.json http://purl.obolibrary.org/obo/GO_0036140 GO:0036141 biolink:MolecularActivity L-phenylalanine-oxaloacetate transaminase activity Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate. go.json L-phenylalanine:oxaloacetate transaminase activity http://purl.obolibrary.org/obo/GO_0036141 GO:0036142 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036142 GO:0036143 biolink:MolecularActivity kringle domain binding Interacting selectively and non-covalently with a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors. go.json http://purl.obolibrary.org/obo/GO_0036143 GO:0036144 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036144 GO:0051731 biolink:MolecularActivity polynucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. go.json polynucleotide kinase activity|polynucleotide 5'-hydroxy-kinase activity|PNK|5'-dephosphopolynucleotide kinase activity|polynucleotide 5'-hydroxyl kinase (phosphorylating) activity|5'-hydroxyl polynucleotide kinase activity http://purl.obolibrary.org/obo/GO_0051731 GO:0051732 biolink:MolecularActivity polyribonucleotide kinase activity Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA. go.json RNA 5'-hydroxyl kinase activity|5'-hydroxyl RNA kinase activity|5'-hydroxyl polyribonucleotide kinase activity|RNA kinase activity http://purl.obolibrary.org/obo/GO_0051732 GO:0051730 biolink:MolecularActivity GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA. go.json GTP-dependent polyribonucleotide kinase activity|GTP-dependent RNA kinase activity|GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent RNA 5'-hydroxyl-kinase activity http://purl.obolibrary.org/obo/GO_0051730 GO:0051735 biolink:MolecularActivity GTP-dependent polynucleotide kinase activity Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. go.json GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0051735 GO:0051736 biolink:MolecularActivity ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA. go.json ATP-dependent RNA kinase activity|ATP-dependent polyribonucleotide kinase activity|ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|ATP-dependent RNA 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity http://purl.obolibrary.org/obo/GO_0051736 GO:0051733 biolink:MolecularActivity polydeoxyribonucleotide kinase activity Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA. go.json DNA 5'-hydroxyl kinase activity|DNA kinase activity http://purl.obolibrary.org/obo/GO_0051733 GO:0075705 biolink:BiologicalProcess obsolete viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane OBSOLETE. The uptake of a virus into a host cell that begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicles containing the virus. The vesicle then delivers its viral content to early endosomes, and the process ends when the viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane. go.json viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane|viral penetration via endocytosis followed by genetic injection through the endosome membrane http://purl.obolibrary.org/obo/GO_0075705 GO:0051734 biolink:MolecularActivity ATP-dependent polynucleotide kinase activity Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. EC:2.7.1.78|RHEA:54580 go.json ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity|ATP:5'-dephosphopolynucleotide 5'-phosphatase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity http://purl.obolibrary.org/obo/GO_0051734 GO:0075706 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0075706 GO:0051739 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051739 GO:0051737 biolink:MolecularActivity GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA. go.json GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent DNA 5'-hydroxyl-kinase activity|GTP-dependent DNA kinase activity|GTP-dependent polydeoxyribonucleotide kinase activity|GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0051737 GO:0051738 biolink:MolecularActivity xanthophyll binding Interacting selectively and non-covalently with xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen. go.json http://purl.obolibrary.org/obo/GO_0051738 GO:0036134 biolink:MolecularActivity 12-hydroxyheptadecatrienoic acid synthase activity Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA). RHEA:48644|Reactome:R-HSA-2161613 go.json prostaglandin H2 degradation activity http://purl.obolibrary.org/obo/GO_0036134 GO:0036135 biolink:BiologicalProcess Schwann cell migration The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function. go.json http://purl.obolibrary.org/obo/GO_0036135 GO:0036136 biolink:MolecularActivity kynurenine-oxaloacetate transaminase activity Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate. go.json L-kynurenine-oxaloacetate transaminase activity http://purl.obolibrary.org/obo/GO_0036136 GO:0036137 biolink:MolecularActivity kynurenine aminotransferase activity Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid. go.json kynurenine-oxo-acid transaminase activity|L-kynurenine transaminase activity http://purl.obolibrary.org/obo/GO_0036137 GO:0036138 biolink:BiologicalProcess peptidyl-histidine hydroxylation The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine. go.json http://purl.obolibrary.org/obo/GO_0036138 GO:0036139 biolink:MolecularActivity peptidyl-histidine dioxygenase activity Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2. go.json http://purl.obolibrary.org/obo/GO_0036139 GO:0036130 biolink:MolecularActivity prostaglandin H2 endoperoxidase reductase activity Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate). RHEA:45312|KEGG_REACTION:R02264|Reactome:R-HSA-2161549 go.json PGH2 9-,11-endoperoxide reductase|PGH2 9,11-endoperoxidase http://purl.obolibrary.org/obo/GO_0036130 GO:0036131 biolink:MolecularActivity prostaglandin D2 11-ketoreductase activity Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+. Reactome:R-HSA-2161614|RHEA:45316|KEGG_REACTION:R02799|EC:1.1.1.188 go.json prostaglandin 11-keto reductase|PGD2 11-ketoreductase http://purl.obolibrary.org/obo/GO_0036131 GO:0036132 biolink:MolecularActivity 13-prostaglandin reductase activity Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin. KEGG_REACTION:R04557|KEGG_REACTION:R04556|EC:1.3.1.48|Reactome:R-HSA-2161692 go.json prostaglandin delta13-reductase activity|15-oxo-delta13-prostaglandin reductase activity|prostaglandin 13-reductase activity|15-ketoprostaglandin delta13-reductase activity|15-oxoprostaglandin 13-reductase activity|delta13-15-ketoprostaglandin reductase activity http://purl.obolibrary.org/obo/GO_0036132 GO:0036133 biolink:MolecularActivity 11-hydroxythromboxane B2 dehydrogenase activity Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+. Reactome:R-HSA-2161732|KEGG_REACTION:R05060|RHEA:52312 go.json NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity http://purl.obolibrary.org/obo/GO_0036133 GO:0051742 biolink:MolecularActivity 2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine. MetaCyc:RXN-2762|RHEA:37999 go.json MSBQ methyltransferase activity http://purl.obolibrary.org/obo/GO_0051742 GO:0051743 biolink:MolecularActivity red chlorophyll catabolite reductase activity Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence. RHEA:24752|MetaCyc:RXN-7741 go.json RCC reductase activity http://purl.obolibrary.org/obo/GO_0051743 GO:0051740 biolink:MolecularActivity ethylene binding Interacting selectively and non-covalently with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. go.json ethene binding http://purl.obolibrary.org/obo/GO_0051740 GO:0051741 biolink:MolecularActivity 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine. MetaCyc:RXN-2542|RHEA:37979 go.json MPBQ methyltransferase activity http://purl.obolibrary.org/obo/GO_0051741 GO:0051746 biolink:MolecularActivity thalianol synthase activity Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol). EC:5.4.99.31|RHEA:26163 go.json http://purl.obolibrary.org/obo/GO_0051746 GO:0051747 biolink:MolecularActivity cytosine C-5 DNA demethylase activity Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA. go.json DNA methyltransferase activity acting on cytosine C-5|hydrolytic DNA demethylase activity|DNA demethylase activity http://purl.obolibrary.org/obo/GO_0051747 GO:0051744 biolink:MolecularActivity 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+. MetaCyc:RXN1F-72|RHEA:48884 go.json http://purl.obolibrary.org/obo/GO_0051744 GO:0051745 biolink:MolecularActivity 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. MetaCyc:ISPH2-RXN|EC:1.17.7.4 go.json 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity|isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051745 GO:0051748 biolink:MolecularActivity UTP-monosaccharide-1-phosphate uridylyltransferase activity Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide. RHEA:13205|MetaCyc:2.7.7.64-RXN|EC:2.7.7.64 go.json UDP-monosaccharide pyrophosphorylase activity|UDP-monosaccharide diphosphorylase activity|UDP-sugar pyrophosphorylase activity|USP|PsUSP http://purl.obolibrary.org/obo/GO_0051748 GO:0051749 biolink:MolecularActivity indole acetic acid carboxyl methyltransferase activity Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine. go.json IAA carboxyl methyltransferase activity http://purl.obolibrary.org/obo/GO_0051749 GO:0036123 biolink:BiologicalProcess histone H3-K9 dimethylation The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone. go.json histone lysine H3 K9 dimethylation|histone H3 K9 dimethylation http://purl.obolibrary.org/obo/GO_0036123 GO:0036124 biolink:BiologicalProcess histone H3-K9 trimethylation The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone. go.json http://purl.obolibrary.org/obo/GO_0036124 GO:0036125 biolink:CellularComponent fatty acid beta-oxidation multienzyme complex A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT). go.json http://purl.obolibrary.org/obo/GO_0036125 GO:0036126 biolink:CellularComponent sperm flagellum A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid. go.json sperm tail|sperm cilium http://purl.obolibrary.org/obo/GO_0036126 GO:0036127 biolink:MolecularActivity 3-sulfino-L-alanine binding Interacting selectively and non-covalently with 3-sulfino-L-alanine (cysteine sulfinate). go.json cysteine sulfinate binding http://purl.obolibrary.org/obo/GO_0036127 GO:0036128 biolink:CellularComponent CatSper complex A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits. go.json CATSPER channel|CatSper channel complex http://purl.obolibrary.org/obo/GO_0036128 GO:0036129 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus. go.json http://purl.obolibrary.org/obo/GO_0036129 GO:0036120 biolink:BiologicalProcess cellular response to platelet-derived growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus. go.json cellular response to PDGF stimulus http://purl.obolibrary.org/obo/GO_0036120 GO:0036121 biolink:MolecularActivity double-stranded DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix. go.json double-stranded DNA-dependent ATP-dependent DNA helicase activity|double-stranded DNA-dependent ATPase activity|dsDNA-dependent ATPase activity|dsDNA-dependent ATP-dependent DNA helicase activity http://purl.obolibrary.org/obo/GO_0036121 GO:0036122 biolink:MolecularActivity BMP binding Interacting selectively and non-covalently with a member of the bone morphogenetic protein (BMP) family. go.json bone morphogenetic protein binding http://purl.obolibrary.org/obo/GO_0036122 GO:0002908 biolink:BiologicalProcess regulation of peripheral B cell deletion Any process that modulates the frequency, rate, or extent of peripheral B cell deletion. go.json http://purl.obolibrary.org/obo/GO_0002908 GO:0002909 biolink:BiologicalProcess negative regulation of peripheral B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion. go.json downregulation of peripheral B cell deletion|down regulation of peripheral B cell deletion|inhibition of peripheral B cell deletion|down-regulation of peripheral B cell deletion http://purl.obolibrary.org/obo/GO_0002909 GO:0002904 biolink:BiologicalProcess positive regulation of B cell apoptotic process Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process. go.json upregulation of B cell apoptosis|stimulation of B cell apoptosis|up regulation of B cell apoptosis|activation of B cell apoptosis|up-regulation of B cell apoptosis|positive regulation of B cell apoptosis http://purl.obolibrary.org/obo/GO_0002904 GO:0002905 biolink:BiologicalProcess regulation of mature B cell apoptotic process Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process. go.json regulation of mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002905 GO:0002906 biolink:BiologicalProcess negative regulation of mature B cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process. go.json down-regulation of mature B cell apoptosis|down regulation of mature B cell apoptosis|inhibition of mature B cell apoptosis|downregulation of mature B cell apoptosis|negative regulation of mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002906 GO:0002907 biolink:BiologicalProcess positive regulation of mature B cell apoptotic process Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process. go.json activation of mature B cell apoptosis|stimulation of mature B cell apoptosis|upregulation of mature B cell apoptosis|positive regulation of mature B cell apoptosis|up-regulation of mature B cell apoptosis|up regulation of mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002907 GO:0002900 biolink:BiologicalProcess positive regulation of central B cell deletion Any process that activates or increases the frequency, rate, or extent of central B cell deletion. go.json up-regulation of central B cell deletion|up regulation of central B cell deletion|activation of central B cell deletion|stimulation of central B cell deletion|upregulation of central B cell deletion http://purl.obolibrary.org/obo/GO_0002900 GO:0002901 biolink:BiologicalProcess mature B cell apoptotic process Any apoptotic process in a B cell that is mature, having left the bone marrow. go.json apoptosis of mature B-lymphocytes|programmed cell death, mature B cells|mature B-lymphocyte programmed cell death by apoptosis|apoptosis of mature B lymphocytes|apoptosis of mature B-cells|programmed cell death of mature B cells by apoptosis|mature B lymphocyte programmed cell death by apoptosis|mature B-cell apoptosis|mature B-cell programmed cell death by apoptosis|apoptosis of mature B cells|mature B lymphocyte apoptosis|programmed cell death, mature B-lymphocytes|programmed cell death of mature B-cells by apoptosis|mature B cell programmed cell death by apoptosis|mature B-lymphocyte apoptosis|programmed cell death of mature B lymphocytes by apoptosis|programmed cell death, mature B lymphocytes|programmed cell death, mature B-cells|programmed cell death of mature B-lymphocytes by apoptosis|mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002901 GO:0002902 biolink:BiologicalProcess regulation of B cell apoptotic process Any process that modulates the frequency, rate, or extent of B cell apoptotic process. go.json regulation of B cell apoptosis http://purl.obolibrary.org/obo/GO_0002902 GO:0002903 biolink:BiologicalProcess negative regulation of B cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process. go.json downregulation of B cell apoptosis|negative regulation of B cell apoptosis|down regulation of B cell apoptosis|inhibition of B cell apoptosis|down-regulation of B cell apoptosis http://purl.obolibrary.org/obo/GO_0002903 GO:0002910 biolink:BiologicalProcess positive regulation of peripheral B cell deletion Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion. go.json upregulation of peripheral B cell deletion|up regulation of peripheral B cell deletion|stimulation of peripheral B cell deletion|up-regulation of peripheral B cell deletion|activation of peripheral B cell deletion http://purl.obolibrary.org/obo/GO_0002910 GO:0002919 biolink:BiologicalProcess positive regulation of peripheral B cell anergy Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy. go.json up regulation of peripheral B cell anergy|stimulation of peripheral B cell anergy|up-regulation of peripheral B cell anergy|activation of peripheral B cell anergy|upregulation of peripheral B cell anergy http://purl.obolibrary.org/obo/GO_0002919 GO:0002915 biolink:BiologicalProcess negative regulation of central B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy. go.json inhibition of central B cell anergy|downregulation of central B cell anergy|down-regulation of central B cell anergy|down regulation of central B cell anergy http://purl.obolibrary.org/obo/GO_0002915 GO:0002916 biolink:BiologicalProcess positive regulation of central B cell anergy Any process that activates or increases the frequency, rate, or extent of central B cell anergy. go.json up-regulation of central B cell anergy|up regulation of central B cell anergy|activation of central B cell anergy|stimulation of central B cell anergy|upregulation of central B cell anergy http://purl.obolibrary.org/obo/GO_0002916 GO:0002917 biolink:BiologicalProcess regulation of peripheral B cell anergy Any process that modulates the frequency, rate, or extent of peripheral B cell anergy. go.json http://purl.obolibrary.org/obo/GO_0002917 GO:0002918 biolink:BiologicalProcess negative regulation of peripheral B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy. go.json downregulation of peripheral B cell anergy|down regulation of peripheral B cell anergy|inhibition of peripheral B cell anergy|down-regulation of peripheral B cell anergy http://purl.obolibrary.org/obo/GO_0002918 GO:0002911 biolink:BiologicalProcess regulation of lymphocyte anergy Any process that modulates the frequency, rate, or extent of lymphocyte anergy. go.json http://purl.obolibrary.org/obo/GO_0002911 GO:0002912 biolink:BiologicalProcess negative regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy. go.json down regulation of lymphocyte anergy|inhibition of lymphocyte anergy|downregulation of lymphocyte anergy|down-regulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002912 GO:0002913 biolink:BiologicalProcess positive regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy. go.json up-regulation of lymphocyte anergy|up regulation of lymphocyte anergy|activation of lymphocyte anergy|stimulation of lymphocyte anergy|upregulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002913 GO:0002914 biolink:BiologicalProcess regulation of central B cell anergy Any process that modulates the frequency, rate, or extent of central B cell anergy. go.json http://purl.obolibrary.org/obo/GO_0002914 GO:0051900 biolink:BiologicalProcess regulation of mitochondrial depolarization Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. go.json http://purl.obolibrary.org/obo/GO_0051900 GO:0051901 biolink:BiologicalProcess positive regulation of mitochondrial depolarization Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. go.json upregulation of mitochondrial depolarization|up regulation of mitochondrial depolarization|stimulation of mitochondrial depolarization|up-regulation of mitochondrial depolarization|activation of mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0051901 GO:0051904 biolink:BiologicalProcess pigment granule transport The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json pigment granule translocation http://purl.obolibrary.org/obo/GO_0051904 GO:0051905 biolink:BiologicalProcess establishment of pigment granule localization The directed movement of a pigment granule to a specific location. go.json establishment of pigment granule localisation http://purl.obolibrary.org/obo/GO_0051905 GO:0051902 biolink:BiologicalProcess negative regulation of mitochondrial depolarization Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. go.json down regulation of mitochondrial depolarization|inhibition of mitochondrial depolarization|down-regulation of mitochondrial depolarization|downregulation of mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0051902 GO:0051903 biolink:MolecularActivity S-(hydroxymethyl)glutathione dehydrogenase activity Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+. EC:1.1.1.284|MetaCyc:RXN-2962|KEGG_REACTION:R06983|Reactome:R-HSA-5692237|KEGG_REACTION:R07140|UM-BBD_reactionID:r1146 go.json chi-ADH activity|ADH3 activity|glutathione-dependent formaldehyde dehydrogenase activity|GD-FALDH activity|S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity|GS-FDH activity|FDH activity|NAD-linked formaldehyde dehydrogenase activity|formic dehydrogenase activity|NAD- and glutathione-dependent formaldehyde dehydrogenase activity|NAD-dependent formaldehyde dehydrogenase activity|class III alcohol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0051903 GO:0051908 biolink:MolecularActivity double-stranded DNA 5'-3' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule. go.json double-stranded DNA specific 5'-3' exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0051908 GO:0051909 biolink:MolecularActivity acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O. EC:4.2.1.27 go.json alkynoate hydratase activity|3-hydroxypropenoate dehydratase activity|acetylenemonocarboxylate hydratase activity|acetylenecarboxylate hydratase activity http://purl.obolibrary.org/obo/GO_0051909 GO:0051906 biolink:BiologicalProcess maintenance of pigment granule location Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere. go.json maintenance of pigment granule localization http://purl.obolibrary.org/obo/GO_0051906 GO:0051907 biolink:MolecularActivity S-(hydroxymethyl)glutathione synthase activity Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione. UM-BBD_reactionID:r1145|EC:4.4.1.22|RHEA:22488|MetaCyc:RXN-2961|KEGG_REACTION:R06982 go.json S-(hydroxymethyl)glutathione formaldehyde-lyase activity|glutathione-dependent formaldehyde-activating enzyme activity|S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)|Gfa http://purl.obolibrary.org/obo/GO_0051907 GO:0061280 biolink:BiologicalProcess epithelial cell migration involved in mesonephric proximal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis. go.json http://purl.obolibrary.org/obo/GO_0061280 GO:0061281 biolink:BiologicalProcess specification of mesonephric connecting tubule identity The process in which the connecting tubule of the mesonephric nephron acquires its identity. go.json specification of mesonephric collecting tubule identity http://purl.obolibrary.org/obo/GO_0061281 GO:0061282 biolink:BiologicalProcess specification of mesonephric nephron tubule identity The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity. go.json http://purl.obolibrary.org/obo/GO_0061282 GO:0061283 biolink:BiologicalProcess specification of mesonephric distal tubule identity The process in which the distal tubule of the mesonephric nephron acquires its identity. go.json http://purl.obolibrary.org/obo/GO_0061283 GO:0061284 biolink:BiologicalProcess specification of mesonephric proximal tubule identity The process in which the proximal tubule of the mesonephric nephron acquires its identity. go.json http://purl.obolibrary.org/obo/GO_0061284 GO:0061285 biolink:BiologicalProcess mesonephric capsule development The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. go.json http://purl.obolibrary.org/obo/GO_0061285 GO:0061286 biolink:BiologicalProcess mesonephric capsule morphogenesis The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. go.json http://purl.obolibrary.org/obo/GO_0061286 GO:0061287 biolink:BiologicalProcess mesonephric capsule formation The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. go.json http://purl.obolibrary.org/obo/GO_0061287 GO:0061288 biolink:BiologicalProcess mesonephric capsule specification The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go.json http://purl.obolibrary.org/obo/GO_0061288 GO:0061289 biolink:BiologicalProcess Wnt signaling pathway involved in kidney development The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time. go.json Wnt receptor signalling pathway involved in kidney development|Wnt-activated signaling pathway involved in kidney development|Wnt receptor signaling pathway involved in kidney development http://purl.obolibrary.org/obo/GO_0061289 GO:0061270 biolink:BiologicalProcess mesonephric intraglomerular mesangial cell proliferation The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. go.json http://purl.obolibrary.org/obo/GO_0061270 GO:0061271 biolink:BiologicalProcess mesenchymal to epithelial transition involved in mesonephric renal vesicle formation A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle. go.json http://purl.obolibrary.org/obo/GO_0061271 GO:0061272 biolink:BiologicalProcess mesonephric connecting tubule development The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. go.json mesonephric collecting tubule development|mesonephric connecting duct development http://purl.obolibrary.org/obo/GO_0061272 GO:0061273 biolink:BiologicalProcess mesonephric distal tubule morphogenesis The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. go.json http://purl.obolibrary.org/obo/GO_0061273 GO:0061274 biolink:BiologicalProcess mesonephric distal tubule development The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. go.json http://purl.obolibrary.org/obo/GO_0061274 GO:0061275 biolink:BiologicalProcess mesonephric proximal tubule development The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. go.json http://purl.obolibrary.org/obo/GO_0061275 GO:0061276 biolink:BiologicalProcess mesonephric proximal tubule morphogenesis The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. go.json http://purl.obolibrary.org/obo/GO_0061276 GO:0061277 biolink:BiologicalProcess mesonephric nephron tubule formation The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061277 GO:0061278 biolink:BiologicalProcess epithelial cell migration involved in mesonephric nephron tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis. go.json http://purl.obolibrary.org/obo/GO_0061278 GO:0061279 biolink:BiologicalProcess epithelial cell migration involved in mesonephric distal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis. go.json http://purl.obolibrary.org/obo/GO_0061279 GO:0061290 biolink:BiologicalProcess canonical Wnt signaling pathway involved in metanephric kidney development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go.json canonical Wnt receptor signaling pathway involved in metanephric kidney development|canonical Wnt receptor signalling pathway involved in metanephric kidney development|canonical Wnt-activated signaling pathway involved in metanephric kidney development http://purl.obolibrary.org/obo/GO_0061290 GO:0061291 biolink:BiologicalProcess canonical Wnt signaling pathway involved in ureteric bud branching The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go.json canonical Wnt receptor signalling pathway involved in ureteric bud branching|canonical Wnt receptor signaling pathway involved in ureteric bud branching http://purl.obolibrary.org/obo/GO_0061291 GO:0061292 biolink:BiologicalProcess canonical Wnt signaling pathway involved in mesonephros development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go.json canonical Wnt receptor signaling pathway involved in mesonephros development|canonical Wnt-activated signaling pathway involved in mesonephros development|canonical Wnt receptor signalling pathway involved in mesonephros development http://purl.obolibrary.org/obo/GO_0061292 GO:0061293 biolink:BiologicalProcess canonical Wnt signaling pathway involved in mesonephric nephron development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go.json canonical Wnt-activated signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signalling pathway involved in mesonephric nephron development http://purl.obolibrary.org/obo/GO_0061293 GO:0061294 biolink:BiologicalProcess mesonephric renal vesicle induction Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle. go.json http://purl.obolibrary.org/obo/GO_0061294 GO:0061295 biolink:BiologicalProcess regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. go.json regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis|regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061295 GO:0061296 biolink:BiologicalProcess negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. go.json negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061296 GO:0061297 biolink:BiologicalProcess positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. go.json positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061297 GO:0061298 biolink:BiologicalProcess retina vasculature development in camera-type eye The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. go.json retinal vasculature development http://purl.obolibrary.org/obo/GO_0061298 GO:0061299 biolink:BiologicalProcess retina vasculature morphogenesis in camera-type eye The process in which the vasculature of the retina is generated and organized. go.json retinal vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0061299 GO:0002940 biolink:BiologicalProcess tRNA N2-guanine methylation The process whereby a guanine in a tRNA is methylated at the N2 position of guanine. go.json tRNA m2-guanine biosynthesis http://purl.obolibrary.org/obo/GO_0002940 GO:0002941 biolink:BiologicalProcess synoviocyte proliferation The multiplication or reproduction of synoviocytes by cell division, resulting in the expansion of their population. A synoviocyte is a fibroblast-like cell found in synovial tissues. go.json http://purl.obolibrary.org/obo/GO_0002941 GO:0002942 biolink:BiologicalProcess tRNA m2,2-guanine biosynthesis The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position. go.json http://purl.obolibrary.org/obo/GO_0002942 GO:0002943 biolink:BiologicalProcess tRNA dihydrouridine synthesis The process whereby a uridine in a transfer RNA is converted to dihydrouridine. go.json http://purl.obolibrary.org/obo/GO_0002943 GO:0002948 biolink:MolecularActivity archaeosine synthase activity Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA. Wikipedia:Archaeosine_synthase|RHEA:54084|EC:2.6.1.97 go.json glutamine:preQ0-tRNA amidinotransferase|ArcS http://purl.obolibrary.org/obo/GO_0002948 GO:0002949 biolink:BiologicalProcess tRNA threonylcarbamoyladenosine modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base). go.json t6A tRNA modification|threonylcarbamoyladenosine biosynthesis|threonylcarbamoyladenosine anabolism|threonylcarbamoyladenosine synthesis|threonylcarbamoyladenosine formation|t6A biosynthesis|t6A biosynthetic process|threonylcarbamoyladenosine biosynthetic process http://purl.obolibrary.org/obo/GO_0002949 GO:0002944 biolink:CellularComponent cyclin K-CDK12 complex A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go.json CycK/Cdk12 complex http://purl.obolibrary.org/obo/GO_0002944 GO:0002945 biolink:CellularComponent cyclin K-CDK13 complex A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go.json CycK/Cdk13 complex http://purl.obolibrary.org/obo/GO_0002945 GO:0002946 biolink:BiologicalProcess tRNA C5-cytosine methylation The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine. go.json tRNA 5-methylcytosine biosynthesis http://purl.obolibrary.org/obo/GO_0002946 GO:0002947 biolink:CellularComponent tumor necrosis factor receptor superfamily complex A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily. go.json TNF receptor superfamily complex http://purl.obolibrary.org/obo/GO_0002947 GO:0002951 biolink:MolecularActivity leukotriene-C(4) hydrolase Catalysis of the reaction Leukotriene C(4) + H(2)O= leukotriene D(4) + L-glutamate. go.json http://purl.obolibrary.org/obo/GO_0002951 GO:0002952 biolink:MolecularActivity (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione. go.json phospho-AI-2 isomerase activity http://purl.obolibrary.org/obo/GO_0002952 GO:0002953 biolink:MolecularActivity 5'-deoxynucleotidase activity Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate. go.json http://purl.obolibrary.org/obo/GO_0002953 GO:0002950 biolink:MolecularActivity ceramide phosphoethanolamine synthase activity Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine. Reactome:R-HSA-8959462 go.json http://purl.obolibrary.org/obo/GO_0002950 GO:0002920 biolink:BiologicalProcess regulation of humoral immune response Any process that modulates the frequency, rate, or extent of a humoral immune response. go.json http://purl.obolibrary.org/obo/GO_0002920 GO:0002921 biolink:BiologicalProcess negative regulation of humoral immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response. go.json inhibition of humoral immune response|downregulation of humoral immune response|down-regulation of humoral immune response|down regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0002921 GO:0002926 biolink:BiologicalProcess tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine. go.json tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis|mcm5s2U34 biosynthesis|mcm5 modification http://purl.obolibrary.org/obo/GO_0002926 GO:0002927 biolink:BiologicalProcess archaeosine-tRNA biosynthetic process The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs. go.json http://purl.obolibrary.org/obo/GO_0002927 GO:0002928 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0002928 GO:0002929 biolink:CellularComponent MECO complex A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II. go.json meta-coactivator complex http://purl.obolibrary.org/obo/GO_0002929 GO:0002922 biolink:BiologicalProcess positive regulation of humoral immune response Any process that activates or increases the frequency, rate, or extent of a humoral immune response. go.json up-regulation of humoral immune response|up regulation of humoral immune response|activation of humoral immune response|stimulation of humoral immune response|upregulation of humoral immune response http://purl.obolibrary.org/obo/GO_0002922 GO:0002923 biolink:BiologicalProcess regulation of humoral immune response mediated by circulating immunoglobulin Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. go.json http://purl.obolibrary.org/obo/GO_0002923 GO:0002924 biolink:BiologicalProcess negative regulation of humoral immune response mediated by circulating immunoglobulin Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. go.json inhibition of humoral immune response mediated by circulating immunoglobulin|down-regulation of humoral immune response mediated by circulating immunoglobulin|downregulation of humoral immune response mediated by circulating immunoglobulin|down regulation of humoral immune response mediated by circulating immunoglobulin http://purl.obolibrary.org/obo/GO_0002924 GO:0002925 biolink:BiologicalProcess positive regulation of humoral immune response mediated by circulating immunoglobulin Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. go.json upregulation of humoral immune response mediated by circulating immunoglobulin|up regulation of humoral immune response mediated by circulating immunoglobulin|stimulation of humoral immune response mediated by circulating immunoglobulin|up-regulation of humoral immune response mediated by circulating immunoglobulin|activation of humoral immune response mediated by circulating immunoglobulin http://purl.obolibrary.org/obo/GO_0002925 GO:0002930 biolink:BiologicalProcess trabecular meshwork development The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor. go.json http://purl.obolibrary.org/obo/GO_0002930 GO:0002931 biolink:BiologicalProcess response to ischemia Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply. go.json http://purl.obolibrary.org/obo/GO_0002931 GO:0002932 biolink:BiologicalProcess tendon sheath development The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. go.json http://purl.obolibrary.org/obo/GO_0002932 GO:0002937 biolink:BiologicalProcess tRNA 4-thiouridine biosynthesis The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs. go.json http://purl.obolibrary.org/obo/GO_0002937 GO:0002938 biolink:BiologicalProcess tRNA guanine ribose methylation The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety. go.json http://purl.obolibrary.org/obo/GO_0002938 GO:0002939 biolink:BiologicalProcess tRNA N1-guanine methylation The process whereby a guanine in tRNA is methylated at position N1 of the guanine. go.json tRNA m1-guanine biosynthesis http://purl.obolibrary.org/obo/GO_0002939 GO:0002933 biolink:BiologicalProcess lipid hydroxylation The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid. go.json fatty acid hydroxylation http://purl.obolibrary.org/obo/GO_0002933 GO:0002934 biolink:BiologicalProcess desmosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. go.json http://purl.obolibrary.org/obo/GO_0002934 GO:0002935 biolink:MolecularActivity tRNA (adenine-C2-)-methyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA. go.json http://purl.obolibrary.org/obo/GO_0002935 GO:0002936 biolink:BiologicalProcess bradykinin biosynthetic process The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin. go.json http://purl.obolibrary.org/obo/GO_0002936 GO:0051874 biolink:BiologicalProcess sphinganine-1-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol. go.json dihydrosphingosine-1-phosphate catabolic process|dihydrosphingosine-1-phosphate catabolism http://purl.obolibrary.org/obo/GO_0051874 GO:0051875 biolink:BiologicalProcess pigment granule localization Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. go.json pigment granule localisation http://purl.obolibrary.org/obo/GO_0051875 GO:0051872 biolink:BiologicalProcess sphingosine catabolic process The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. go.json (4E)-sphing-4-enine catabolism|sphing-4-enine catabolism|sphing-4-enine catabolic process|(4E)-sphing-4-enine catabolic process http://purl.obolibrary.org/obo/GO_0051872 GO:0051873 biolink:BiologicalProcess killing by host of symbiont cells Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json disruption by host of symbiont cells http://purl.obolibrary.org/obo/GO_0051873 GO:0051878 biolink:BiologicalProcess lateral element assembly The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements. go.json http://purl.obolibrary.org/obo/GO_0051878 GO:0051879 biolink:MolecularActivity Hsp90 protein binding Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size. go.json Hsp90 class protein binding|Hsp90 binding http://purl.obolibrary.org/obo/GO_0051879 GO:0051876 biolink:BiologicalProcess pigment granule dispersal The directed movement of pigment granules within a cell towards the cell periphery. go.json http://purl.obolibrary.org/obo/GO_0051876 GO:0051877 biolink:BiologicalProcess pigment granule aggregation in cell center The directed movement of dispersed pigment granules towards the center of the cell. go.json http://purl.obolibrary.org/obo/GO_0051877 GO:0061200 biolink:CellularComponent clathrin-sculpted gamma-aminobutyric acid transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle. go.json clathrin sculpted gamma-aminobutyric acid transport vesicle|clathrin sculpted GABA transport vesicle http://purl.obolibrary.org/obo/GO_0061200 GO:0036233 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036233 GO:0061201 biolink:CellularComponent clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle. go.json clathrin sculpted GABA transport vesicle lumen|clathrin sculpted gamma-aminobutyric acid transport vesicle lumen http://purl.obolibrary.org/obo/GO_0061201 GO:0036234 biolink:BiologicalProcess deglucuronidation The removal of glucuronic acid from a conjugated substrate. go.json http://purl.obolibrary.org/obo/GO_0036234 GO:0036235 biolink:BiologicalProcess acyl deglucuronidation The removal of glucuronic acid from an acyl-glucuronide. go.json http://purl.obolibrary.org/obo/GO_0036235 GO:0061202 biolink:CellularComponent clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle. go.json clathrin sculpted GABA transport vesicle membrane|clathrin sculpted gamma-aminobutyric acid transport vesicle membrane http://purl.obolibrary.org/obo/GO_0061202 GO:0036236 biolink:BiologicalProcess acyl glucuronidation The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside). go.json http://purl.obolibrary.org/obo/GO_0036236 GO:0061203 biolink:BiologicalProcess striated muscle paramyosin thick filament assembly The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle. go.json http://purl.obolibrary.org/obo/GO_0061203 GO:0036237 biolink:MolecularActivity acyl-glucuronidase activity Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate. go.json acyl-glucuronide deglucuronidation activity http://purl.obolibrary.org/obo/GO_0036237 GO:0061204 biolink:BiologicalProcess paramyosin filament assembly or disassembly The formation or disassembly of a filament composed of paramyosin molecules. go.json http://purl.obolibrary.org/obo/GO_0061204 GO:0061205 biolink:BiologicalProcess paramesonephric duct development The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. go.json Mullerian duct development http://purl.obolibrary.org/obo/GO_0061205 GO:0036238 biolink:MolecularActivity gallate dioxygenase activity Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate. KEGG_REACTION:R09565|MetaCyc:GALLATE-DIOXYGENASE-RXN|RHEA:28927|EC:1.13.11.57 go.json http://purl.obolibrary.org/obo/GO_0036238 GO:0061206 biolink:BiologicalProcess mesonephros morphogenesis The process in which the anatomical structures of the mesonephros are generated and organized. go.json Wolffian body morphogenesis http://purl.obolibrary.org/obo/GO_0061206 GO:0036239 biolink:MolecularActivity taxoid 7beta-hydroxylase activity Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O. RHEA:31975|MetaCyc:RXN-12885|KEGG_REACTION:R09868|EC:1.14.13.147 go.json http://purl.obolibrary.org/obo/GO_0036239 GO:0061207 biolink:BiologicalProcess mesonephric juxtaglomerulus cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061207 GO:0061208 biolink:BiologicalProcess cell differentiation involved in mesonephros development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061208 GO:0061209 biolink:BiologicalProcess cell proliferation involved in mesonephros development The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061209 GO:0051870 biolink:MolecularActivity methotrexate binding Interacting selectively and non-covalently with methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. go.json http://purl.obolibrary.org/obo/GO_0051870 GO:0051871 biolink:MolecularActivity dihydrofolic acid binding Interacting selectively and non-covalently with dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms. go.json dihydrofolate binding|DHF binding http://purl.obolibrary.org/obo/GO_0051871 GO:0036230 biolink:BiologicalProcess granulocyte activation The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go.json http://purl.obolibrary.org/obo/GO_0036230 GO:0036231 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036231 GO:0036232 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036232 GO:0051885 biolink:BiologicalProcess positive regulation of timing of anagen Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. go.json upregulation of anagen|stimulation of anagen|positive regulation of anagen|activation of anagen|up regulation of anagen|up-regulation of anagen http://purl.obolibrary.org/obo/GO_0051885 GO:0051886 biolink:BiologicalProcess negative regulation of timing of anagen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. go.json downregulation of anagen|inhibition of anagen|down regulation of anagen|negative regulation of anagen|down-regulation of anagen http://purl.obolibrary.org/obo/GO_0051886 GO:0051883 biolink:BiologicalProcess killing of cells in other organism involved in symbiotic interaction Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction. go.json killing of cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051883 GO:0051884 biolink:BiologicalProcess regulation of timing of anagen Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. go.json regulation of anagen http://purl.obolibrary.org/obo/GO_0051884 GO:0051889 biolink:BiologicalProcess negative regulation of timing of exogen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. go.json down-regulation of exogen|negative regulation of exogen|downregulation of exogen|inhibition of exogen|down regulation of exogen http://purl.obolibrary.org/obo/GO_0051889 GO:0051887 biolink:BiologicalProcess regulation of timing of exogen Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. go.json regulation of exogen http://purl.obolibrary.org/obo/GO_0051887 GO:0051888 biolink:BiologicalProcess positive regulation of timing of exogen Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. go.json upregulation of exogen|stimulation of exogen|positive regulation of exogen|activation of exogen|up regulation of exogen|up-regulation of exogen http://purl.obolibrary.org/obo/GO_0051888 GO:0036222 biolink:MolecularActivity XTP diphosphatase activity Catalysis of the reaction: XTP + H2O <=> H+ + XDP + monophosphate. KEGG_REACTION:R02720|EC:3.6.1.66|MetaCyc:RXN0-1603|MetaCyc:RXN0-5074|Reactome:R-HSA-2509831|RHEA:28610 go.json XTP pyrophosphohydrolase activity|XTP/dITP diphosphatase|XTPase activity|hypoxanthine/xanthine dNTP pyrophosphatase http://purl.obolibrary.org/obo/GO_0036222 GO:0036223 biolink:BiologicalProcess cellular response to adenine starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine. go.json cellular response to adenine deprivation http://purl.obolibrary.org/obo/GO_0036223 GO:0036224 biolink:CellularComponent pairing center A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment. go.json homolog recognition region http://purl.obolibrary.org/obo/GO_0036224 GO:0036225 biolink:BiologicalProcess cellular response to vitamin B1 starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine). go.json cellular response to thiamin starvation|cellular response to vitamin B1 deprivation http://purl.obolibrary.org/obo/GO_0036225 GO:0036226 biolink:BiologicalProcess obsolete mitotic cell cycle arrest in response to glucose starvation OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose. go.json cell cycle arrest in response to glucose starvation http://purl.obolibrary.org/obo/GO_0036226 GO:0036227 biolink:BiologicalProcess mitotic G2 cell cycle arrest in response to glucose starvation The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose. go.json http://purl.obolibrary.org/obo/GO_0036227 GO:0036228 biolink:BiologicalProcess protein localization to nuclear inner membrane A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane. go.json protein targeting to INM|protein targeting to nuclear inner membrane http://purl.obolibrary.org/obo/GO_0036228 GO:0036229 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036229 GO:0051881 biolink:BiologicalProcess regulation of mitochondrial membrane potential Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go.json http://purl.obolibrary.org/obo/GO_0051881 GO:0051882 biolink:BiologicalProcess mitochondrial depolarization The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level. go.json mitochondrion depolarization|mitochondria depolarization|mitochondrial depolarisation|mitochondrial membrane depolarization http://purl.obolibrary.org/obo/GO_0051882 GO:0036220 biolink:MolecularActivity ITP diphosphatase activity Catalysis of the reaction: ITP + H2O = IMP + diphosphate. KEGG_REACTION:R00720|Reactome:R-HSA-2509827|MetaCyc:RXN0-6382|RHEA:29399 go.json inosine-5'-triphosphate pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0036220 GO:0036221 biolink:MolecularActivity UTP diphosphatase activity Catalysis of the reaction: UTP + H2O = UMP + diphosphate. RHEA:29395|KEGG_REACTION:R00662 go.json uridine triphosphate pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0036221 GO:0051880 biolink:MolecularActivity G-quadruplex DNA binding Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. go.json G-DNA binding|quadruplex DNA binding|G-quartet DNA binding|G quartet DNA binding|G-quartet binding|tetraplex DNA binding|G quadruplex DNA binding|G quartet binding http://purl.obolibrary.org/obo/GO_0051880 GO:0051896 biolink:BiologicalProcess regulation of protein kinase B signaling Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. go.json regulation of PKB signalling cascade|regulation of protein kinase B signalling cascade|regulation of AKT signalling cascade|regulation of protein kinase B signaling cascade|regulation of AKT signaling cascade|regulation of PKB signaling cascade http://purl.obolibrary.org/obo/GO_0051896 GO:0051897 biolink:BiologicalProcess positive regulation of protein kinase B signaling Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. go.json positive regulation of PKB signaling cascade|upregulation of protein kinase B signaling cascade|positive regulation of AKT signaling cascade|stimulation of protein kinase B signaling cascade|activation of protein kinase B signaling cascade|up regulation of protein kinase B signaling cascade|positive regulation of AKT signalling cascade|positive regulation of protein kinase B signalling cascade|positive regulation of PKB signalling cascade|up-regulation of protein kinase B signaling cascade|positive regulation of protein kinase B signaling cascade http://purl.obolibrary.org/obo/GO_0051897 GO:0051894 biolink:BiologicalProcess positive regulation of focal adhesion assembly Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. go.json up regulation of focal adhesion formation|stimulation of focal adhesion formation|up-regulation of focal adhesion formation|activation of focal adhesion formation|upregulation of focal adhesion formation http://purl.obolibrary.org/obo/GO_0051894 GO:0051895 biolink:BiologicalProcess negative regulation of focal adhesion assembly Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. go.json downregulation of focal adhesion formation|down regulation of focal adhesion formation|inhibition of focal adhesion formation|down-regulation of focal adhesion formation http://purl.obolibrary.org/obo/GO_0051895 GO:0051898 biolink:BiologicalProcess negative regulation of protein kinase B signaling Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. go.json down-regulation of protein kinase B signaling cascade|negative regulation of PKB signaling cascade|negative regulation of AKT signalling cascade|negative regulation of AKT signaling cascade|negative regulation of PKB signalling cascade|negative regulation of protein kinase B signaling cascade|downregulation of protein kinase B signaling cascade|inhibition of protein kinase B signaling cascade|negative regulation of protein kinase B signalling cascade|down regulation of protein kinase B signaling cascade http://purl.obolibrary.org/obo/GO_0051898 GO:0051899 biolink:BiologicalProcess membrane depolarization The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential. go.json http://purl.obolibrary.org/obo/GO_0051899 GO:0036219 biolink:MolecularActivity GTP diphosphatase activity Catalysis of the reaction: GTP + H2O = GMP + diphosphate. KEGG_REACTION:R00426|RHEA:29391 go.json GTP diphosphohydrolase activity|GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase http://purl.obolibrary.org/obo/GO_0036219 GO:0061220 biolink:BiologicalProcess mesonephric macula densa development The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. go.json http://purl.obolibrary.org/obo/GO_0061220 GO:0061221 biolink:BiologicalProcess mesonephric mesenchyme morphogenesis The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061221 GO:0036211 biolink:BiologicalProcess protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). go.json protein modification http://purl.obolibrary.org/obo/GO_0036211 GO:0061222 biolink:BiologicalProcess mesonephric mesenchymal cell proliferation involved in mesonephros development The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population. go.json http://purl.obolibrary.org/obo/GO_0061222 GO:0036212 biolink:BiologicalProcess contractile ring maintenance The process in which the contractile ring is maintained, typically in response to an internal or external cue. go.json http://purl.obolibrary.org/obo/GO_0036212 GO:0061223 biolink:BiologicalProcess mesonephric mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061223 GO:0036213 biolink:BiologicalProcess contractile ring contraction The process of an actomyosin ring getting smaller in diameter. go.json http://purl.obolibrary.org/obo/GO_0036213 GO:0061224 biolink:BiologicalProcess mesonephric glomerulus development The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061224 GO:0036214 biolink:BiologicalProcess contractile ring localization The process in which a contractile ring is assembled and/or maintained in a specific location. go.json http://purl.obolibrary.org/obo/GO_0036214 GO:0061225 biolink:BiologicalProcess mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. go.json mesonephric lacis cell proliferation|mesonephric Goormaghtigh proliferation http://purl.obolibrary.org/obo/GO_0061225 GO:0036215 biolink:BiologicalProcess response to stem cell factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus. go.json response to hematopoietic growth factor KL|response to stem cell factor stimulus|response to SCF|response to KIT ligand http://purl.obolibrary.org/obo/GO_0036215 GO:0061226 biolink:BiologicalProcess proximal/distal pattern formation involved in mesonephric nephron development The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end). go.json http://purl.obolibrary.org/obo/GO_0061226 GO:0036216 biolink:BiologicalProcess cellular response to stem cell factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus. go.json cellular response to SCF|cellular response to KIT ligand|cellular response to KITLG|cellular response to hematopoietic growth factor KL http://purl.obolibrary.org/obo/GO_0036216 GO:0061227 biolink:BiologicalProcess pattern specification involved in mesonephros development Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate. go.json mesonephros pattern specification|mesonephros pattern formation http://purl.obolibrary.org/obo/GO_0061227 GO:0036217 biolink:MolecularActivity dGTP diphosphatase activity Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate. RHEA:28362|KEGG_REACTION:R01855 go.json 2'-deoxyguanosine 5'-triphosphate diphosphohydrolase http://purl.obolibrary.org/obo/GO_0036217 GO:0061228 biolink:BiologicalProcess mesonephric nephron morphogenesis The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061228 GO:0061229 biolink:BiologicalProcess mesonephric juxtaglomerulus cell development The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061229 GO:0036218 biolink:MolecularActivity dTTP diphosphatase activity Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate. RHEA:28534|MetaCyc:RXN0-5107|EC:3.6.1.9 go.json http://purl.obolibrary.org/obo/GO_0036218 GO:0051892 biolink:BiologicalProcess negative regulation of cardioblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go.json down regulation of cardioblast differentiation|downregulation of cardioblast differentiation|inhibition of cardioblast differentiation|down-regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051892 GO:0051893 biolink:BiologicalProcess regulation of focal adhesion assembly Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions. go.json regulation of adhesion plaque assembly http://purl.obolibrary.org/obo/GO_0051893 GO:0051890 biolink:BiologicalProcess regulation of cardioblast differentiation Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go.json http://purl.obolibrary.org/obo/GO_0051890 GO:0051891 biolink:BiologicalProcess positive regulation of cardioblast differentiation Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go.json up-regulation of cardioblast differentiation|up regulation of cardioblast differentiation|activation of cardioblast differentiation|stimulation of cardioblast differentiation|upregulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051891 GO:0036210 biolink:BiologicalProcess protein modification process in other organism The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). go.json protein modification in other organism http://purl.obolibrary.org/obo/GO_0036210 GO:0036208 biolink:BiologicalProcess obsolete negative regulation of histone gene expression OBSOLETE. Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. go.json negative regulation of expression of histone-encoding gene|down-regulation of histone gene expression|downregulation of histone gene expression|inhibition of histone gene expression http://purl.obolibrary.org/obo/GO_0036208 GO:0036209 biolink:MolecularActivity 9beta-pimara-7,15-diene oxidase activity Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 NADPH + 3 H+ = 9beta-pimara-7,15-dien-19-oate + 3 NADP+ + 4 H2O. This is a three-step reaction: (a) 9beta-pimara-7,15-diene + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-ol + NADP+ + H2O, (b) 9beta-pimara-7,15-dien-19-ol + O2 + NADPH + H+ = 9neta-pimara-7,15-dien-19-al + NADP+ + 2 H2O, (c) 9beta-pimara-7,15-dien-19-al + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-oate + NADP+ + H2O. KEGG_REACTION:R09865|EC:1.14.14.111|RHEA:31951 go.json http://purl.obolibrary.org/obo/GO_0036209 GO:0061210 biolink:BiologicalProcess cell-cell signaling involved in mesonephros development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ. go.json cell-cell signalling involved in mesonephros development http://purl.obolibrary.org/obo/GO_0061210 GO:0061211 biolink:BiologicalProcess mesonephric collecting duct development The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. go.json http://purl.obolibrary.org/obo/GO_0061211 GO:0036200 biolink:MolecularActivity 3-ketosteroid 9-alpha-monooxygenase activity Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O. EC:1.14.15.30|KEGG_REACTION:R09860|RHEA:32199 go.json KshAB activity|3-ketosteroid 9alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0036200 GO:0036201 biolink:MolecularActivity ent-isokaurene C2-hydroxylase activity Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+. KEGG_REACTION:R09861|RHEA:56336|EC:1.14.14.76 go.json http://purl.obolibrary.org/obo/GO_0036201 GO:0061212 biolink:BiologicalProcess mesonephric juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. go.json http://purl.obolibrary.org/obo/GO_0061212 GO:0036202 biolink:MolecularActivity ent-cassa-12,15-diene 11-hydroxylase activity Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O. RHEA:31967|KEGG_REACTION:R09866|EC:1.14.14.112 go.json ent-cassadiene C11alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0036202 GO:0061213 biolink:BiologicalProcess positive regulation of mesonephros development Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go.json http://purl.obolibrary.org/obo/GO_0061213 GO:0061214 biolink:BiologicalProcess mesonephric smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061214 GO:0036203 biolink:MolecularActivity taxoid 14-beta-hydroxylase activity Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O. RHEA:31971|KEGG_REACTION:R09867|EC:1.14.13.146 go.json http://purl.obolibrary.org/obo/GO_0036203 GO:0036204 biolink:MolecularActivity abieta-7,13-dien-18-ol hydroxylase activity Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O. EC:1.14.14.145|KEGG_REACTION:R06354|RHEA:26221|MetaCyc:RXN-12799 go.json http://purl.obolibrary.org/obo/GO_0036204 GO:0061215 biolink:BiologicalProcess mesonephric nephron development The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. go.json http://purl.obolibrary.org/obo/GO_0061215 GO:0061216 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in mesonephros development Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061216 GO:0036205 biolink:BiologicalProcess histone catabolic process The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells. go.json histone protein catabolic process http://purl.obolibrary.org/obo/GO_0036205 GO:0036206 biolink:BiologicalProcess obsolete regulation of histone gene expression OBSOLETE. Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. go.json regulation of expression of histone-encoding gene http://purl.obolibrary.org/obo/GO_0036206 GO:0061217 biolink:BiologicalProcess regulation of mesonephros development Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. go.json http://purl.obolibrary.org/obo/GO_0061217 GO:0061218 biolink:BiologicalProcess negative regulation of mesonephros development Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go.json http://purl.obolibrary.org/obo/GO_0061218 GO:0036207 biolink:BiologicalProcess obsolete positive regulation of histone gene expression OBSOLETE. Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. go.json upregulation of histone gene expression|up-regulation of histone gene expression|activation of histone gene expression|positive regulation of expression of histone-encoding gene http://purl.obolibrary.org/obo/GO_0036207 GO:0061219 biolink:BiologicalProcess mesonephric mesenchyme development The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061219 GO:0061240 biolink:BiologicalProcess mesonephric nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061240 GO:0061241 biolink:BiologicalProcess mesonephric nephron epithelium development The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061241 GO:0061242 biolink:BiologicalProcess mesonephric nephron tubule development The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061242 GO:0061243 biolink:BiologicalProcess mesonephric renal vesicle morphogenesis The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. go.json http://purl.obolibrary.org/obo/GO_0061243 GO:0061244 biolink:BiologicalProcess mesonephric S-shaped body morphogenesis The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061244 GO:0061245 biolink:BiologicalProcess establishment or maintenance of bipolar cell polarity Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns. go.json http://purl.obolibrary.org/obo/GO_0061245 GO:0061246 biolink:BiologicalProcess establishment or maintenance of bipolar cell polarity regulating cell shape Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell. go.json http://purl.obolibrary.org/obo/GO_0061246 GO:0061247 biolink:BiologicalProcess mesonephric glomerular mesangium development The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. go.json http://purl.obolibrary.org/obo/GO_0061247 GO:0061248 biolink:BiologicalProcess mesonephric glomerulus vasculature morphogenesis The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. go.json http://purl.obolibrary.org/obo/GO_0061248 GO:0061249 biolink:BiologicalProcess mesonephric glomerular capillary formation The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. go.json http://purl.obolibrary.org/obo/GO_0061249 GO:0061230 biolink:BiologicalProcess mesonephric juxtaglomerulus cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell. go.json http://purl.obolibrary.org/obo/GO_0061230 GO:0061231 biolink:BiologicalProcess mesonephric glomerulus vasculature development The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. go.json http://purl.obolibrary.org/obo/GO_0061231 GO:0061232 biolink:BiologicalProcess mesonephric glomerular epithelium development The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061232 GO:0061233 biolink:BiologicalProcess mesonephric glomerular basement membrane development The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration. go.json http://purl.obolibrary.org/obo/GO_0061233 GO:0061234 biolink:BiologicalProcess mesonephric glomerulus morphogenesis The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061234 GO:0061235 biolink:BiologicalProcess mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go.json http://purl.obolibrary.org/obo/GO_0061235 GO:0061236 biolink:BiologicalProcess mesonephric comma-shaped body morphogenesis The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061236 GO:0061237 biolink:BiologicalProcess convergent extension involved in mesonephric nephron morphogenesis The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061237 GO:0061238 biolink:BiologicalProcess establishment of planar polarity involved in mesonephric nephron morphogenesis Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros. go.json establishment of planar cell polarity involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061238 GO:0061239 biolink:BiologicalProcess mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go.json http://purl.obolibrary.org/obo/GO_0061239 GO:0002885 biolink:BiologicalProcess positive regulation of hypersensitivity Any process that activates or increases the frequency, rate, or extent of hypersensitivity. go.json up regulation of hypersensitivity|stimulation of hypersensitivity|up-regulation of hypersensitivity|activation of hypersensitivity|upregulation of hypersensitivity http://purl.obolibrary.org/obo/GO_0002885 GO:0002886 biolink:BiologicalProcess regulation of myeloid leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. go.json http://purl.obolibrary.org/obo/GO_0002886 GO:0002887 biolink:BiologicalProcess negative regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. go.json down-regulation of myeloid leukocyte mediated immunity|down regulation of myeloid leukocyte mediated immunity|inhibition of myeloid leukocyte mediated immunity|downregulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002887 GO:0002888 biolink:BiologicalProcess positive regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. go.json upregulation of myeloid leukocyte mediated immunity|up-regulation of myeloid leukocyte mediated immunity|up regulation of myeloid leukocyte mediated immunity|activation of myeloid leukocyte mediated immunity|stimulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002888 GO:0002881 biolink:BiologicalProcess negative regulation of chronic inflammatory response to non-antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. go.json down-regulation of chronic inflammatory response to non-antigenic stimulus|down regulation of chronic inflammatory response to non-antigenic stimulus|downregulation of chronic inflammatory response to non-antigenic stimulus|inhibition of chronic inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002881 GO:0002882 biolink:BiologicalProcess positive regulation of chronic inflammatory response to non-antigenic stimulus Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. go.json up regulation of chronic inflammatory response to non-antigenic stimulus|activation of chronic inflammatory response to non-antigenic stimulus|stimulation of chronic inflammatory response to non-antigenic stimulus|upregulation of chronic inflammatory response to non-antigenic stimulus|up-regulation of chronic inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002882 GO:0002883 biolink:BiologicalProcess regulation of hypersensitivity Any process that modulates the frequency, rate, or extent of hypersensitivity. go.json http://purl.obolibrary.org/obo/GO_0002883 GO:0002884 biolink:BiologicalProcess negative regulation of hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity. go.json downregulation of hypersensitivity|down regulation of hypersensitivity|inhibition of hypersensitivity|down-regulation of hypersensitivity http://purl.obolibrary.org/obo/GO_0002884 GO:0061260 biolink:BiologicalProcess mesonephric mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061260 GO:0061261 biolink:BiologicalProcess mesenchymal to epithelial transition involved in mesonephros morphogenesis A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros. go.json mesonephric mesenchyme to epithelial transition http://purl.obolibrary.org/obo/GO_0061261 GO:0002880 biolink:BiologicalProcess regulation of chronic inflammatory response to non-antigenic stimulus Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. go.json http://purl.obolibrary.org/obo/GO_0002880 GO:0061262 biolink:BiologicalProcess mesonephric renal vesicle formation The developmental process pertaining to the initial formation of the mesonephros. go.json mesonephros formation http://purl.obolibrary.org/obo/GO_0061262 GO:0061263 biolink:BiologicalProcess mesonephric glomerular mesangial cell development The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061263 GO:0061264 biolink:BiologicalProcess mesonephric glomerular mesangial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell. go.json http://purl.obolibrary.org/obo/GO_0061264 GO:0061265 biolink:BiologicalProcess mesonephric nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061265 GO:0061266 biolink:BiologicalProcess mesonephric interstitial fibroblast differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state. go.json mesonephros interstitial cell differentiation http://purl.obolibrary.org/obo/GO_0061266 GO:0061267 biolink:BiologicalProcess mesonephric interstitial fibroblast development The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure. go.json mesonephros interstitial cell development http://purl.obolibrary.org/obo/GO_0061267 GO:0061268 biolink:BiologicalProcess mesonephric interstitial fibroblast fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast. go.json http://purl.obolibrary.org/obo/GO_0061268 GO:0061269 biolink:BiologicalProcess mesonephric glomerular mesangial cell proliferation involved in mesonephros development The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population. go.json http://purl.obolibrary.org/obo/GO_0061269 GO:0002889 biolink:BiologicalProcess regulation of immunoglobulin mediated immune response Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response. go.json http://purl.obolibrary.org/obo/GO_0002889 GO:0002896 biolink:BiologicalProcess negative regulation of central B cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction. go.json down regulation of central B cell tolerance induction|inhibition of central B cell tolerance induction|down-regulation of central B cell tolerance induction|downregulation of central B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002896 GO:0002897 biolink:BiologicalProcess positive regulation of central B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction. go.json upregulation of central B cell tolerance induction|up regulation of central B cell tolerance induction|stimulation of central B cell tolerance induction|up-regulation of central B cell tolerance induction|activation of central B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002897 GO:0002898 biolink:BiologicalProcess regulation of central B cell deletion Any process that modulates the frequency, rate, or extent of central B cell deletion. go.json http://purl.obolibrary.org/obo/GO_0002898 GO:0002899 biolink:BiologicalProcess negative regulation of central B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion. go.json down-regulation of central B cell deletion|down regulation of central B cell deletion|inhibition of central B cell deletion|downregulation of central B cell deletion http://purl.obolibrary.org/obo/GO_0002899 GO:0002892 biolink:BiologicalProcess regulation of type II hypersensitivity Any process that modulates the frequency, rate, or extent of type II hypersensitivity. go.json http://purl.obolibrary.org/obo/GO_0002892 GO:0002893 biolink:BiologicalProcess negative regulation of type II hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity. go.json downregulation of type II hypersensitivity|down regulation of type II hypersensitivity|inhibition of type II hypersensitivity|down-regulation of type II hypersensitivity http://purl.obolibrary.org/obo/GO_0002893 GO:0002894 biolink:BiologicalProcess positive regulation of type II hypersensitivity Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity. go.json up regulation of type II hypersensitivity|stimulation of type II hypersensitivity|activation of type II hypersensitivity|up-regulation of type II hypersensitivity|upregulation of type II hypersensitivity http://purl.obolibrary.org/obo/GO_0002894 GO:0002895 biolink:BiologicalProcess regulation of central B cell tolerance induction Any process that modulates the frequency, rate, or extent of central B cell tolerance induction. go.json http://purl.obolibrary.org/obo/GO_0002895 GO:0002890 biolink:BiologicalProcess negative regulation of immunoglobulin mediated immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response. go.json inhibition of immunoglobulin mediated immune response|downregulation of immunoglobulin mediated immune response|down-regulation of immunoglobulin mediated immune response|down regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002890 GO:0002891 biolink:BiologicalProcess positive regulation of immunoglobulin mediated immune response Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response. go.json up-regulation of immunoglobulin mediated immune response|up regulation of immunoglobulin mediated immune response|activation of immunoglobulin mediated immune response|stimulation of immunoglobulin mediated immune response|upregulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002891 GO:0061250 biolink:BiologicalProcess mesonephric glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. go.json http://purl.obolibrary.org/obo/GO_0061250 GO:0061251 biolink:BiologicalProcess mesonephric glomerular epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. go.json http://purl.obolibrary.org/obo/GO_0061251 GO:0061252 biolink:BiologicalProcess mesonephric glomerular epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. go.json http://purl.obolibrary.org/obo/GO_0061252 GO:0061253 biolink:BiologicalProcess mesonephric glomerular parietal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go.json http://purl.obolibrary.org/obo/GO_0061253 GO:0061254 biolink:BiologicalProcess mesonephric glomerular parietal epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go.json http://purl.obolibrary.org/obo/GO_0061254 GO:0061255 biolink:BiologicalProcess mesonephric glomerular parietal epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. go.json http://purl.obolibrary.org/obo/GO_0061255 GO:0061256 biolink:BiologicalProcess mesonephric glomerular visceral epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061256 GO:0061257 biolink:BiologicalProcess mesonephric glomerular visceral epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061257 GO:0061258 biolink:BiologicalProcess mesonephric glomerular visceral epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go.json http://purl.obolibrary.org/obo/GO_0061258 GO:0061259 biolink:BiologicalProcess mesonephric glomerular mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061259 GO:0051801 biolink:BiologicalProcess cytolysis in other organism involved in symbiotic interaction The killing by an organism of a cell in a second organism by means of the rupture of cell membranes and the loss of cytoplasm, where the two organisms are in a symbiotic interaction. go.json cytolysis of cells in other organism involved in symbiotic interaction|cytolysis of cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051801 GO:0051802 biolink:BiologicalProcess regulation of cytolysis in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. go.json regulation of cytolysis of cells in other organism during symbiotic interaction|regulation of cytolysis of cells in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051802 GO:0051800 biolink:MolecularActivity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate. Reactome:R-HSA-1676149|Reactome:R-HSA-1676204 go.json PTEN activity http://purl.obolibrary.org/obo/GO_0051800 GO:0051805 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051805 GO:0051806 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051806 GO:0051803 biolink:BiologicalProcess negative regulation of cytolysis in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. go.json down-regulation of cytolysis of cells in other organism during symbiotic interaction|inhibition of cytolysis of cells in other organism during symbiotic interaction|down regulation of cytolysis of cells in other organism during symbiotic interaction|downregulation of cytolysis of cells in other organism during symbiotic interaction|negative regulation of cytolysis of cells in other organism involved in symbiotic interaction|negative regulation of cytolysis of cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051803 GO:0051804 biolink:BiologicalProcess positive regulation of cytolysis in other organism involved in symbiotic interaction Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. go.json up-regulation of cytolysis of cells in other organism during symbiotic interaction|up regulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism during symbiotic interaction|activation of cytolysis of cells in other organism during symbiotic interaction|stimulation of cytolysis of cells in other organism during symbiotic interaction|upregulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051804 GO:0051809 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051809 GO:0051807 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051807 GO:0051808 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051808 GO:0051812 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051812 GO:0051813 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051813 GO:0051810 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051810 GO:0051811 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051811 GO:0051816 biolink:BiologicalProcess acquisition of nutrients from other organism during symbiotic interaction The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from a second organism, where the two organisms are in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0051816 GO:0051817 biolink:BiologicalProcess modulation of process of other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction. go.json modification of morphology or physiology of other organism during symbiotic interaction|modulation of biological process of other organism involved in symbiotic interaction|regulation of morphology or physiology of other organism during symbiotic interaction|modulation of morphology or physiology of other organism during symbiotic interaction|modification of morphology or physiology of other organism involved in symbiotic interaction|regulation of morphology of other organism during symbiotic interaction|regulation of physiological process in other organism during symbiotic interaction|regulation of physiology of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051817 GO:0051814 biolink:BiologicalProcess obsolete movement in other organism involved in symbiotic interaction OBSOLETE. The process in which an organism or its progeny spreads from one location to another within a second organism, where the two organisms are in a symbiotic interaction. go.json movement in other organism during symbiotic interaction|movement within other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051814 GO:0051815 biolink:BiologicalProcess obsolete migration in other organism involved in symbiotic interaction OBSOLETE. The directional movement of an organism from one place to another within a second organism, where the two organisms are in a symbiotic interaction. go.json migration within other organism during symbiotic interaction|migration in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051815 GO:0051818 biolink:BiologicalProcess disruption of cells of other organism involved in symbiotic interaction A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction. go.json disruption of cells of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051818 GO:0051819 biolink:BiologicalProcess induction by symbiont of tumor or growth in host The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic. go.json induction by symbiont in host of tumor, nodule, or growth|induction by symbiont of nodulation, tumor or growth in host|induction of tumor, nodule, or growth in other organism during symbiotic interaction|induction by symbiont in host of tumor, nodule, or growth containing transformed cells|induction of tumor, nodule, or growth containing transformed cells in other organism during symbiotic interaction|induction of tumor, nodule, or growth containing transformed cells in other organism involved in symbiotic interaction|induction of tumor, nodule, or growth in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051819 GO:0036299 biolink:BiologicalProcess non-recombinational interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination. go.json recombination-independent ICL repair|recombination-independent interstrand cross-link repair http://purl.obolibrary.org/obo/GO_0036299 GO:0036291 biolink:BiologicalProcess protein cis-autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues. go.json cis-autophosphorylation http://purl.obolibrary.org/obo/GO_0036291 GO:0036292 biolink:BiologicalProcess DNA rewinding The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA. go.json RPA-dependent DNA rewinding|single-stranded DNA bubble rewinding|DNA annealing http://purl.obolibrary.org/obo/GO_0036292 GO:0036293 biolink:BiologicalProcess response to decreased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. go.json response to lowered oxygen levels http://purl.obolibrary.org/obo/GO_0036293 GO:0036294 biolink:BiologicalProcess cellular response to decreased oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. go.json cellular response to lowered oxygen levels http://purl.obolibrary.org/obo/GO_0036294 GO:0036295 biolink:BiologicalProcess cellular response to increased oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. go.json cellular response to raised oxygen levels http://purl.obolibrary.org/obo/GO_0036295 GO:0036296 biolink:BiologicalProcess response to increased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. go.json response to raised oxygen levels http://purl.obolibrary.org/obo/GO_0036296 GO:0036297 biolink:BiologicalProcess interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. go.json ICL repair http://purl.obolibrary.org/obo/GO_0036297 GO:0036298 biolink:BiologicalProcess recombinational interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA. go.json recombination-dependent interstrand cross-link repair http://purl.obolibrary.org/obo/GO_0036298 GO:0051820 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051820 GO:0051823 biolink:BiologicalProcess regulation of synapse structural plasticity Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane. go.json regulation of synaptic structural plasticity http://purl.obolibrary.org/obo/GO_0051823 GO:0051824 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051824 GO:0051821 biolink:BiologicalProcess obsolete dissemination or transmission of organism from other organism involved in symbiotic interaction OBSOLETE. The movement of an organism from a second organism to another place in the environment, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism. go.json dissemination or transmission of organism from other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051821 GO:0036290 biolink:BiologicalProcess protein trans-autophosphorylation The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer. go.json trans-autophosphorylation http://purl.obolibrary.org/obo/GO_0036290 GO:0051822 biolink:BiologicalProcess obsolete dissemination or transmission of organism from other organism by vector involved in symbiotic interaction OBSOLETE. The movement of an organism from a second organism to another place in the environment by means of a vector, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism, and the vector organism is often an insect or an animal. go.json dissemination or transmission of organism from other organism by vector during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051822 GO:0051827 biolink:BiologicalProcess obsolete growth or development on or near surface of other organism during symbiotic interaction OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction. go.json growth or development on or near surface of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051827 GO:0051828 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051828 GO:0051825 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051825 GO:0051826 biolink:BiologicalProcess negative regulation of synapse structural plasticity Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity. go.json inhibition of synapse structural plasticity|downregulation of synapse structural plasticity|down-regulation of synapse structural plasticity|down regulation of synapse structural plasticity http://purl.obolibrary.org/obo/GO_0051826 GO:0120006 biolink:BiologicalProcess regulation of glutamatergic neuron differentiation Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation. go.json http://purl.obolibrary.org/obo/GO_0120006 GO:0120007 biolink:BiologicalProcess negative regulation of glutamatergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation. go.json http://purl.obolibrary.org/obo/GO_0120007 GO:0120008 biolink:BiologicalProcess positive regulation of glutamatergic neuron differentiation Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation. go.json http://purl.obolibrary.org/obo/GO_0120008 GO:0051829 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051829 GO:0120009 biolink:BiologicalProcess intermembrane lipid transfer The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). go.json http://purl.obolibrary.org/obo/GO_0120009 GO:0036288 biolink:BiologicalProcess response to ximelagatran Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus. go.json http://purl.obolibrary.org/obo/GO_0036288 gocheck_do_not_manually_annotate GO:0120002 biolink:CellularComponent fusiform vesicle A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder. go.json http://purl.obolibrary.org/obo/GO_0120002 GO:0120003 biolink:CellularComponent hinge region between urothelial plaques of apical plasma membrane A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane. go.json http://purl.obolibrary.org/obo/GO_0120003 GO:0036289 biolink:BiologicalProcess peptidyl-serine autophosphorylation The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein. go.json serine autophosphorylation http://purl.obolibrary.org/obo/GO_0036289 GO:0120001 biolink:CellularComponent apical plasma membrane urothelial plaque A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array. go.json asymmetric unit membrane|AUM http://purl.obolibrary.org/obo/GO_0120001 GO:0036280 biolink:BiologicalProcess cellular response to L-canavanine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. go.json http://purl.obolibrary.org/obo/GO_0036280 GO:0036281 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036281 GO:0036282 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036282 GO:0036283 biolink:BiologicalProcess obsolete positive regulation of transcription factor import into nucleus in response to oxidative stress OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress. go.json positive regulation of transcription factor import into nucleus in response to hydrogen peroxide http://purl.obolibrary.org/obo/GO_0036283 GO:0036284 biolink:CellularComponent tubulobulbar complex Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes. go.json TBC http://purl.obolibrary.org/obo/GO_0036284 GO:0036285 biolink:BiologicalProcess SAGA complex assembly The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof. go.json SAGA complex formation http://purl.obolibrary.org/obo/GO_0036285 GO:0036286 biolink:CellularComponent eisosome filament A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1. go.json linear eisosome http://purl.obolibrary.org/obo/GO_0036286 GO:0036287 biolink:BiologicalProcess response to iloperidone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus. go.json http://purl.obolibrary.org/obo/GO_0036287 gocheck_do_not_manually_annotate GO:0051830 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051830 GO:0051831 biolink:BiologicalProcess obsolete growth or development in other organism during symbiotic interaction OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism. go.json growth or development within other organism during symbiotic interaction|growth or development in other organism during symbiotic interaction|invasive growth http://purl.obolibrary.org/obo/GO_0051831 GO:0051834 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051834 GO:0051835 biolink:BiologicalProcess positive regulation of synapse structural plasticity Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity. go.json up-regulation of synapse structural plasticity|up regulation of synapse structural plasticity|activation of synapse structural plasticity|stimulation of synapse structural plasticity|upregulation of synapse structural plasticity http://purl.obolibrary.org/obo/GO_0051835 GO:0051832 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051832 GO:0051833 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051833 GO:0051838 biolink:BiologicalProcess cytolysis by host of symbiont cells The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0051838 GO:0051839 biolink:BiologicalProcess regulation by host of cytolysis of symbiont cells Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0051839 GO:0051836 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051836 GO:0051837 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051837 GO:0036277 biolink:BiologicalProcess response to anticonvulsant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity. go.json http://purl.obolibrary.org/obo/GO_0036277 gocheck_do_not_manually_annotate GO:0036278 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen. go.json http://purl.obolibrary.org/obo/GO_0036278 GO:0036279 biolink:BiologicalProcess positive regulation of protein export from nucleus in response to glucose starvation Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose. go.json http://purl.obolibrary.org/obo/GO_0036279 GO:0036270 biolink:BiologicalProcess response to diuretic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function. go.json http://purl.obolibrary.org/obo/GO_0036270 gocheck_do_not_manually_annotate GO:0036271 biolink:BiologicalProcess response to methylphenidate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus. go.json response to MPD|response to ritalin|response to MPH http://purl.obolibrary.org/obo/GO_0036271 gocheck_do_not_manually_annotate GO:0036272 biolink:BiologicalProcess response to gemcitabine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas. go.json response to 2',2'-difluorodeoxycytidine|response to 2'-deoxy-2',2'-difluorocytidine http://purl.obolibrary.org/obo/GO_0036272 gocheck_do_not_manually_annotate GO:0036273 biolink:BiologicalProcess response to statin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. go.json response to HMG-CoA reductase inhibitor|response to hydroxymethylglutaryl-CoA reductase inhibitor http://purl.obolibrary.org/obo/GO_0036273 gocheck_do_not_manually_annotate GO:0036274 biolink:BiologicalProcess response to lapatinib Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus. go.json http://purl.obolibrary.org/obo/GO_0036274 gocheck_do_not_manually_annotate GO:0036275 biolink:BiologicalProcess response to 5-fluorouracil Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus. go.json response to fluorouracil|response to 5-fluoropyrimidine-2,4(1H,3H)-dione http://purl.obolibrary.org/obo/GO_0036275 gocheck_do_not_manually_annotate GO:0036276 biolink:BiologicalProcess response to antidepressant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug. go.json http://purl.obolibrary.org/obo/GO_0036276 gocheck_do_not_manually_annotate GO:0051841 biolink:BiologicalProcess positive regulation by host of cytolysis of symbiont cells Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json upregulation by host of cytolysis of symbiont cells|up-regulation by host of cytolysis of symbiont cells|up regulation by host of cytolysis of symbiont cells|activation by host of cytolysis of symbiont cells|stimulation by host of cytolysis of symbiont cells http://purl.obolibrary.org/obo/GO_0051841 GO:0051842 biolink:BiologicalProcess obsolete evasion or tolerance of symbiont immune response OBSOLETE. Any process, either active or passive, by which an organism avoids the effects of the symbiont organism's immune response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json immune evasion|evasion or tolerance of symbiont immune response http://purl.obolibrary.org/obo/GO_0051842 GO:0051840 biolink:BiologicalProcess negative regulation by host of cytolysis of symbiont cells Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json down-regulation by host of cytolysis of symbiont cells|down regulation by host of cytolysis of symbiont cells|inhibition by host of cytolysis of symbiont cells|downregulation by host of cytolysis of symbiont cells http://purl.obolibrary.org/obo/GO_0051840 GO:0051845 biolink:BiologicalProcess obsolete passive evasion of symbiont immune response OBSOLETE. Any mechanism of immune avoidance that does not directly interfere with the symbiont immune system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json passive evasion of symbiont immune response|passive immune evasion http://purl.obolibrary.org/obo/GO_0051845 GO:0051846 biolink:BiologicalProcess obsolete active evasion of symbiont immune response OBSOLETE. Any mechanism of immune avoidance that directly affects the symbiont immune system, e.g. blocking any stage in symbiont MHC class I and II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json active evasion of symbiont immune response|active immune evasion http://purl.obolibrary.org/obo/GO_0051846 GO:0051843 biolink:BiologicalProcess obsolete evasion or tolerance of symbiont defense response OBSOLETE. Any process, either active or passive, by which an organism avoids or tolerates the effects of a symbiont organism's defense response. The symbiont defense response is mounted by the symbiont in response to the presence of the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json evasion of symbiont defence response|evasion or tolerance of symbiont defense response http://purl.obolibrary.org/obo/GO_0051843 GO:0051844 biolink:BiologicalProcess translocation of peptides or proteins into symbiont The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json transport of peptides or proteins into symbiont http://purl.obolibrary.org/obo/GO_0051844 GO:0051849 biolink:BiologicalProcess obsolete active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json active immune evasion via regulation of symbiont antigen processing or presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation|active immune evasion via modulation of symbiont antigen processing/presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation pathway|active immune evasion via modulation of symbiont antigen processing and presentation http://purl.obolibrary.org/obo/GO_0051849 GO:0051847 biolink:BiologicalProcess obsolete active evasion of symbiont immune response via regulation of symbiont complement system OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, symbiont macrophages, which are eventually destroyed. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json active immune evasion via regulation of symbiont complement system|active evasion of symbiont immune response via regulation of symbiont complement system|active immune evasion via modulation of symbiont complement system http://purl.obolibrary.org/obo/GO_0051847 GO:0051848 biolink:BiologicalProcess obsolete active evasion of symbiont immune response via regulation of symbiont cytokine network OBSOLETE. Any mechanism of active immune avoidance which works by regulating symbiont cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester symbiont cytokines and inhibit action. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json active evasion of symbiont immune response via regulation of symbiont cytokine network|active immune evasion via regulation of symbiont cytokine network|active immune evasion via modulation of symbiont cytokine network http://purl.obolibrary.org/obo/GO_0051848 GO:0036266 biolink:CellularComponent Cdc48p-Npl4p-Vms1p AAA ATPase complex A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p. go.json Vms1-Cdc48-Npl4 complex|Vms1p-Cdc48p-Npl4p complex|Cdc48p-Npl4p-Vms1p complex http://purl.obolibrary.org/obo/GO_0036266 GO:0036267 biolink:BiologicalProcess invasive filamentous growth The growth of colonies in filamentous chains of cells into a substrate. go.json invasive growth http://purl.obolibrary.org/obo/GO_0036267 GO:0036268 biolink:BiologicalProcess swimming Self-propelled movement of an organism from one location to another through water, often by means of active fin movement. go.json http://purl.obolibrary.org/obo/GO_0036268 GO:0036269 biolink:BiologicalProcess swimming behavior The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water. go.json swimming behaviour http://purl.obolibrary.org/obo/GO_0036269 GO:0036260 biolink:BiologicalProcess RNA capping The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts. go.json http://purl.obolibrary.org/obo/GO_0036260 GO:0036261 biolink:BiologicalProcess 7-methylguanosine cap hypermethylation Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation. go.json m(7)G cap hypermethylation|hypermethylation of snRNA cap|snRNA capping|hypermethylation of snoRNA cap|conversion of m(7)G to m(3)G|2,2,7-trimethylguanosine cap formation|snoRNA capping|TMG cap formation http://purl.obolibrary.org/obo/GO_0036261 GO:0036262 biolink:BiologicalProcess granulysin production The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go.json http://purl.obolibrary.org/obo/GO_0036262 gocheck_do_not_annotate GO:0036263 biolink:MolecularActivity L-DOPA monooxygenase activity Catalysis of the reaction: L-DOPA + O2 = ? + H2O. This reaction catalyzes the oxygenation of the dopamine precursor L-DOPA, to the corresponding o-quinone. go.json http://purl.obolibrary.org/obo/GO_0036263 GO:0036264 biolink:MolecularActivity dopamine monooxygenase activity Catalysis of the reaction: dopamine + O2 = ? + H2O. This reaction catalyzes the oxygenation of dopamine to the corresponding o-quinone. go.json http://purl.obolibrary.org/obo/GO_0036264 GO:0036265 biolink:BiologicalProcess RNA (guanine-N7)-methylation The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule. go.json http://purl.obolibrary.org/obo/GO_0036265 GO:0051852 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051852 GO:0051853 biolink:BiologicalProcess obsolete induction in symbiont of tumor, nodule, or growth OBSOLETE. The process by which an associated organism causes the formation of an abnormal mass of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json induction in symbiont of tumor, nodule, or growth http://purl.obolibrary.org/obo/GO_0051853 GO:0051850 biolink:BiologicalProcess acquisition of nutrients from symbiont The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0051850 GO:0051851 biolink:BiologicalProcess modulation by host of symbiont process The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json modification by host of symbiont morphology or physiology http://purl.obolibrary.org/obo/GO_0051851 GO:0051856 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051856 GO:0051857 biolink:BiologicalProcess obsolete growth or development of organism on or near symbiont surface OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json growth or development of organism during interaction with symbiont|growth or development of organism on or near symbiont surface http://purl.obolibrary.org/obo/GO_0051857 GO:0051854 biolink:BiologicalProcess obsolete induction in symbiont of tumor, nodule, or growth containing transformed cells OBSOLETE. The process by which an organism causes the formation in its symbiont organism of an abnormal growth whose cells have been transformed and continue to exist in the absence of the first organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json induction in symbiont of tumor, nodule, or growth containing transformed cells http://purl.obolibrary.org/obo/GO_0051854 GO:0051855 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051855 GO:0051858 biolink:BiologicalProcess obsolete avoidance of symbiont defenses OBSOLETE. Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of its symbiont organism's defense(s). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0051858 GO:0051859 biolink:BiologicalProcess obsolete suppression of symbiont defenses OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont defense(s) by active mechanisms that normally result in the shutting down of a symbiont pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0051859 GO:0036255 biolink:BiologicalProcess response to methylamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus. go.json http://purl.obolibrary.org/obo/GO_0036255 GO:0036256 biolink:BiologicalProcess cellular response to methylamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus. go.json http://purl.obolibrary.org/obo/GO_0036256 GO:0036257 biolink:BiologicalProcess multivesicular body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. go.json MVB organization http://purl.obolibrary.org/obo/GO_0036257 GO:0036258 biolink:BiologicalProcess multivesicular body assembly The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. go.json multivesicular body biogenesis|MVB formation|MVB biogenesis http://purl.obolibrary.org/obo/GO_0036258 GO:0036259 biolink:BiologicalProcess aerobic raffinose catabolic process The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen. go.json aerobic raffinose degradation|aerobic raffinose breakdown|aerobic raffinose catabolism http://purl.obolibrary.org/obo/GO_0036259 GO:0036250 biolink:BiologicalProcess peroxisome transport along microtubule The directed movement of a peroxisome along a microtubule, mediated by motor proteins. go.json http://purl.obolibrary.org/obo/GO_0036250 GO:0036251 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to salt stress OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go.json http://purl.obolibrary.org/obo/GO_0036251 GO:0036252 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to menadione Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position. go.json positive regulation of transcription from RNA polymerase II promoter in response to menadione stress http://purl.obolibrary.org/obo/GO_0036252 GO:0036253 biolink:BiologicalProcess response to amiloride Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus. go.json http://purl.obolibrary.org/obo/GO_0036253 GO:0036254 biolink:BiologicalProcess cellular response to amiloride Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus. go.json http://purl.obolibrary.org/obo/GO_0036254 GO:0051863 biolink:BiologicalProcess obsolete translocation of DNA into symbiont OBSOLETE. The directed movement of DNA from an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json translocation of DNA into symbiont http://purl.obolibrary.org/obo/GO_0051863 GO:0051864 biolink:MolecularActivity histone demethylase activity (H3-K36 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein. RHEA:42032|EC:1.14.11.27|MetaCyc:RXN-8661|MetaCyc:RXN-8660 go.json JmjC domain-containing histone demethylase 1A activity|JHDM1A activity|protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity|histone H3-lysine-36 demethylase activity|histone-lysine (H3-K36) demethylase activity|[histone-H3]-lysine-36 demethylase activity|H3-K36-specific demethylase activity|histone-lysine demethylase activity (H3-K36 specific)|histone-lysine(H3-K36) demethylase activity|protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051864 GO:0051861 biolink:MolecularActivity glycolipid binding Interacting selectively and non-covalently with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate. go.json http://purl.obolibrary.org/obo/GO_0051861 GO:0051862 biolink:BiologicalProcess translocation of molecules into symbiont The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json transport of molecules into symbiont http://purl.obolibrary.org/obo/GO_0051862 GO:0051867 biolink:BiologicalProcess general adaptation syndrome, behavioral process The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus. go.json behavioural process during general adaptation syndrome|behavioural response during general adaptation syndrome|general adaptation syndrome, behavioural process|behavioral process during general adaptation syndrome|general adaptation syndrome, behavioral response|behavioral response during general adaptation syndrome|general adaptation syndrome, behavioural response http://purl.obolibrary.org/obo/GO_0051867 GO:0051868 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051868 GO:0051865 biolink:BiologicalProcess protein autoubiquitination The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink. go.json protein autoubiquitinylation|protein self-ubiquitination|protein self-ubiquitinylation|protein auto-ubiquitination|protein auto-ubiquitinylation http://purl.obolibrary.org/obo/GO_0051865 GO:0051866 biolink:BiologicalProcess general adaptation syndrome General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses. go.json general adaptation syndrome, physiological response|physiological response during general adaptation syndrome|physiological process during general adaptation syndrome|general adaptation syndrome, physiological process http://purl.obolibrary.org/obo/GO_0051866 GO:0051869 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051869 GO:0036244 biolink:BiologicalProcess cellular response to neutral pH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go.json http://purl.obolibrary.org/obo/GO_0036244 GO:0036245 biolink:BiologicalProcess cellular response to menadione Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position. go.json cellular response to vitamin K3 http://purl.obolibrary.org/obo/GO_0036245 GO:0036246 biolink:BiologicalProcess phytochelatin 2 import into vacuole The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. go.json PC2 import into vacuole http://purl.obolibrary.org/obo/GO_0036246 GO:0036247 biolink:BiologicalProcess phytochelatin 3 import into vacuole The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. go.json PC3 import into vacuole http://purl.obolibrary.org/obo/GO_0036247 GO:0036248 biolink:BiologicalProcess phytochelatin 4 import into vacuole The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. go.json PC4 import into vacuole http://purl.obolibrary.org/obo/GO_0036248 GO:0036249 biolink:BiologicalProcess cadmium ion import into vacuole The directed movement of cadmium ions into the vacuole. go.json vacuolar cadmium import http://purl.obolibrary.org/obo/GO_0036249 GO:0036240 biolink:CellularComponent septal periplasm The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi. go.json cell wall-enclosed septal periplasm http://purl.obolibrary.org/obo/GO_0036240 GO:0036241 biolink:BiologicalProcess glutamate catabolic process to 4-hydroxybutyrate The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate. go.json glutamate degradation to 4-hydroxybutyrate http://purl.obolibrary.org/obo/GO_0036241 GO:0051860 biolink:BiologicalProcess obsolete evasion or tolerance of symbiont defenses OBSOLETE. The process, either active or passive, by which an organism evades or tolerates the effects of the defense(s) or defense molecules of a symbiont organism. Symbiont defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go.json http://purl.obolibrary.org/obo/GO_0051860 GO:0036242 biolink:BiologicalProcess glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase. MetaCyc:PWY3O-210|MetaCyc:PWY-4321 go.json glutamate degradation via gamma aminobutyrate transaminase activity http://purl.obolibrary.org/obo/GO_0036242 GO:0036243 biolink:MolecularActivity succinate-semialdehyde dehydrogenase (NADP+) activity Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+. RHEA:13213|EC:1.2.1.79 go.json succinyl semialdehyde dehydrogenase (NADP+) activity|NADP-dependent succinate-semialdehyde dehydrogenase activity|succinate semialdehyde:NADP+ oxidoreductase activity|succinic semialdehyde dehydrogenase (NADP+) activity http://purl.obolibrary.org/obo/GO_0036243 GO:0120299 biolink:MolecularActivity peptide histaminyltransferase activity Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein]. RHEA:66564 go.json http://purl.obolibrary.org/obo/GO_0120299 GO:0120295 biolink:MolecularActivity histone serotonyltransferase activity Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+). go.json http://purl.obolibrary.org/obo/GO_0120295 GO:0120296 biolink:MolecularActivity peptide dopaminyltransferase activity Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+). RHEA:66556 go.json http://purl.obolibrary.org/obo/GO_0120296 GO:0120297 biolink:MolecularActivity histone dopaminyltransferase activity Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+). go.json http://purl.obolibrary.org/obo/GO_0120297 GO:0120298 biolink:MolecularActivity peptide noradrenalinyltransferase activity Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+). RHEA:66560 go.json http://purl.obolibrary.org/obo/GO_0120298 GO:0120291 biolink:BiologicalProcess negative regulation of mitotic recombination involved in replication fork processing Any process that inhibits or decreases the rate of mitotic DNA recombination during replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching. go.json negative regulation of template switch recombination involved in replication fork processing|maintenance of template fidelity during replication fork processing|suppression of template switching during replication fork processing http://purl.obolibrary.org/obo/GO_0120291 GO:0120292 biolink:BiologicalProcess positive regulation of mitotic recombination-dependent replication fork processing Any process that activates or increases the frequency, rate or extent of replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart. go.json positive regulation of homologous recombination dependent replication fork recovery|positive regulation of recombination-dependent DNA replication|positive regulation of homologous recombination-dependent replication fork processing http://purl.obolibrary.org/obo/GO_0120292 GO:0120293 biolink:CellularComponent dynein axonemal particle An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm. go.json DynAP http://purl.obolibrary.org/obo/GO_0120293 GO:0120294 biolink:MolecularActivity peptide serotonyltransferase activity Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+). RHEA:66552 go.json http://purl.obolibrary.org/obo/GO_0120294 GO:0120290 biolink:BiologicalProcess stalled replication fork localization to nuclear periphery A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication. go.json stalled replication fork localization to nuclear periphery involved in replication fork processing http://purl.obolibrary.org/obo/GO_0120290 GO:0120259 biolink:CellularComponent 7SK snRNP A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb. go.json snRNP 7SK http://purl.obolibrary.org/obo/GO_0120259 GO:0120255 biolink:BiologicalProcess olefinic compound biosynthetic process The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). go.json alkene substituted compound synthesis|alkene substituted compound biosynthesis|alkene substituted compound biosynthetic process|alkene substituted compound anabolic process|alkene substituted compound anabolism http://purl.obolibrary.org/obo/GO_0120255 GO:0120256 biolink:BiologicalProcess olefinic compound catabolic process The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). go.json alkene substituted compound degradation|alkene substituted compound catabolism|alkene substituted compound breakdown|alkene substituted compound catabolic process http://purl.obolibrary.org/obo/GO_0120256 GO:0120257 biolink:BiologicalProcess peptidyl-threonine acetylation The acetylation of peptidyl-threonine. go.json http://purl.obolibrary.org/obo/GO_0120257 GO:0120258 biolink:BiologicalProcess peptidyl-threonine O-acetylation The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine. RESID:AA0364 go.json http://purl.obolibrary.org/obo/GO_0120258 GO:0120251 biolink:BiologicalProcess hydrocarbon biosynthetic process The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only. go.json hydrocarbon anabolism|hydrocarbon synthesis|hydrocarbon biosynthesis|hydrocarbon formation http://purl.obolibrary.org/obo/GO_0120251 GO:0120252 biolink:BiologicalProcess hydrocarbon metabolic process The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only. go.json hydrocarbon metabolism http://purl.obolibrary.org/obo/GO_0120252 GO:0120253 biolink:BiologicalProcess hydrocarbon catabolic process The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only. go.json hydrocarbon degradation|hydrocarbon catabolism|hydrocarbon breakdown http://purl.obolibrary.org/obo/GO_0120253 GO:0120254 biolink:BiologicalProcess olefinic compound metabolic process The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). go.json alkene substituted compound metabolic process|alkene substituted compound metabolism http://purl.obolibrary.org/obo/GO_0120254 GO:0120250 biolink:MolecularActivity fatty acid omega-hydroxylase activity Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:39023 go.json http://purl.obolibrary.org/obo/GO_0120250 GO:0120266 biolink:BiologicalProcess positive regulation of chromosome attachment to the nuclear envelope Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope. go.json stimulation of chromosome attachment to the nuclear envelope|upregulation of chromosome attachment to the nuclear envelope|up-regulation of chromosome attachment to the nuclear envelope|up regulation of chromosome attachment to the nuclear envelope|activation of chromosome attachment to the nuclear envelope http://purl.obolibrary.org/obo/GO_0120266 GO:0120267 biolink:CellularComponent pellicular membrane The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles. go.json pellicle membrane|pellicular plasma membrane http://purl.obolibrary.org/obo/GO_0120267 GO:0120268 biolink:BiologicalProcess paraflagellar rod assembly The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. go.json PFR assembly|paraflagellar rod formation|paraflagellar rod biogenesis http://purl.obolibrary.org/obo/GO_0120268 GO:0120269 biolink:CellularComponent ciliary centrin arm A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules. go.json http://purl.obolibrary.org/obo/GO_0120269 GO:0120262 biolink:BiologicalProcess negative regulation of heterochromatin organization Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization. go.json down regulation of heterochromatin organization|inhibition of heterochromatin organization|negative regulation of heterochromatin organization|down-regulation of heterochromatin organization|downregulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_0120262 GO:0120263 biolink:BiologicalProcess positive regulation of heterochromatin organization Any process that activates or increases the frequency, rate or extent of heterochromatin organization. go.json upregulation of heterochromatin organization|positive regulation of heterochromatin organization|up regulation of heterochromatin organization|stimulation of heterochromatin organization|up-regulation of heterochromatin organization|activation of heterochromatin organization http://purl.obolibrary.org/obo/GO_0120263 GO:0120264 biolink:BiologicalProcess regulation of chromosome attachment to the nuclear envelope Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope. go.json http://purl.obolibrary.org/obo/GO_0120264 GO:0120265 biolink:BiologicalProcess negative regulation of chromosome attachment to the nuclear envelope Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope. go.json down-regulation of chromosome attachment to the nuclear envelope|down regulation of chromosome attachment to the nuclear envelope|inhibition of chromosome attachment to the nuclear envelope|downregulation of chromosome attachment to the nuclear envelope http://purl.obolibrary.org/obo/GO_0120265 GO:0120260 biolink:CellularComponent ciliary microtubule quartet A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape. go.json ciliary MtQ http://purl.obolibrary.org/obo/GO_0120260 GO:0120261 biolink:BiologicalProcess regulation of heterochromatin organization Any process that modulates the frequency, rate, extent or location of heterochromatin organization. go.json http://purl.obolibrary.org/obo/GO_0120261 GO:0120277 biolink:BiologicalProcess positive regulation of cerebral blood circulation Any process that activates or increases the frequency, rate or extent of cerebral blood circulation. go.json up regulation of cerebral blood circulation|positive regulation of cerebrum blood circulation|up-regulation of cerebral blood circulation|activation of cerebral blood circulation|positive regulation of telencephalon blood circulation|upregulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120277 GO:0120278 biolink:BiologicalProcess negative regulation of cerebral blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation. go.json negative regulation of cerebrum blood circulation|negative regulation of telencephalon blood circulation|downregulation of cerebral blood circulation|down regulation of cerebral blood circulation|inhibition of cerebral blood circulation|down-regulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120278 GO:0120279 biolink:CellularComponent Z granule A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans. go.json germline granule http://purl.obolibrary.org/obo/GO_0120279 GO:0120273 biolink:BiologicalProcess ciliary centrin arm assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules. go.json ciliary centrin arm formation http://purl.obolibrary.org/obo/GO_0120273 GO:0120274 biolink:MolecularActivity virus coreceptor activity Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity. go.json viral coreceptor activity http://purl.obolibrary.org/obo/GO_0120274 GO:0120275 biolink:BiologicalProcess cerebral blood circulation The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products. go.json telencephelon blood circulation|cerebrum blood circulation http://purl.obolibrary.org/obo/GO_0120275 GO:0120276 biolink:BiologicalProcess regulation of cerebral blood circulation Any process that modulates the frequency, rate or extent of cerebral blood circulation. go.json regulation of telencephalon blood circulation|regulation of cerebrum blood circulation http://purl.obolibrary.org/obo/GO_0120276 GO:0120270 biolink:BiologicalProcess regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. go.json http://purl.obolibrary.org/obo/GO_0120270 GO:0120271 biolink:BiologicalProcess negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. go.json http://purl.obolibrary.org/obo/GO_0120271 GO:0120272 biolink:BiologicalProcess positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. go.json http://purl.obolibrary.org/obo/GO_0120272 GO:0120288 biolink:BiologicalProcess negative regulation of aspartic endopeptidase activity, intramembrane cleaving Any process that decreases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. go.json http://purl.obolibrary.org/obo/GO_0120288 GO:0120289 biolink:BiologicalProcess positive regulation of aspartic endopeptidase activity, intramembrane cleaving Any process that increases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. go.json http://purl.obolibrary.org/obo/GO_0120289 GO:0120284 biolink:MolecularActivity tryptophan binding Interacting selectively and non-covalently with 2-amino-3-(1H-indol-3-yl)propanoic acid. go.json Trp binding http://purl.obolibrary.org/obo/GO_0120284 GO:0120285 biolink:MolecularActivity tyrosine sensor activity Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of tyrosine. go.json http://purl.obolibrary.org/obo/GO_0120285 GO:0120286 biolink:MolecularActivity tryptophan sensor activity Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of tryptophan. go.json http://purl.obolibrary.org/obo/GO_0120286 GO:0120287 biolink:BiologicalProcess regulation of aspartic endopeptidase activity, intramembrane cleaving Any process that modulates the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. go.json http://purl.obolibrary.org/obo/GO_0120287 GO:0120280 biolink:CellularComponent ciliary pro-basal body The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium. go.json flagellar pro-basal body|pro-basal body|flagellar probasal body|probasal body|pro-centriole http://purl.obolibrary.org/obo/GO_0120280 GO:0120281 biolink:CellularComponent autolysosome membrane A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded. go.json http://purl.obolibrary.org/obo/GO_0120281 GO:0120282 biolink:CellularComponent autolysosome lumen The volume that is enclosed within the autolysosome single-membrane. go.json http://purl.obolibrary.org/obo/GO_0120282 GO:0120283 biolink:MolecularActivity protein serine/threonine kinase binding Interacting selectively and non-covalently with a protein serine/threonine kinase. go.json http://purl.obolibrary.org/obo/GO_0120283 GO:1901169 biolink:BiologicalProcess 3-chlorocatechol biosynthetic process The chemical reactions and pathways resulting in the formation of 3-chlorocatechol. go.json 3-chlorocatechol anabolism|3-chlorocatechol synthesis|3-chlorocatechol formation|3-chlorocatechol biosynthesis http://purl.obolibrary.org/obo/GO_1901169 GO:1901167 biolink:BiologicalProcess 3-chlorocatechol metabolic process The chemical reactions and pathways involving 3-chlorocatechol. go.json 3-chlorocatechol metabolism http://purl.obolibrary.org/obo/GO_1901167 GO:1901168 biolink:BiologicalProcess 3-chlorocatechol catabolic process The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol. go.json 3-chlorocatechol degradation|3-chlorocatechol breakdown|3-chlorocatechol catabolism http://purl.obolibrary.org/obo/GO_1901168 GO:1901165 biolink:BiologicalProcess positive regulation of trophoblast cell migration Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. go.json up regulation of trophoblast cell migration|up-regulation of trophoblast cell migration|activation of trophoblast cell migration|upregulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_1901165 GO:1901166 biolink:BiologicalProcess neural crest cell migration involved in autonomic nervous system development Any neural crest cell migration that is involved in autonomic nervous system development. go.json http://purl.obolibrary.org/obo/GO_1901166 GO:1901174 biolink:BiologicalProcess phytoene biosynthetic process The chemical reactions and pathways resulting in the formation of phytoene. go.json phytoene synthesis|phytoene formation|phytoene biosynthesis|phytoene anabolism http://purl.obolibrary.org/obo/GO_1901174 GO:1901175 biolink:BiologicalProcess lycopene metabolic process The chemical reactions and pathways involving lycopene. go.json lycopene metabolism http://purl.obolibrary.org/obo/GO_1901175 GO:1901172 biolink:BiologicalProcess phytoene metabolic process The chemical reactions and pathways involving phytoene. go.json phytoene metabolism http://purl.obolibrary.org/obo/GO_1901172 GO:1901173 biolink:BiologicalProcess phytoene catabolic process The chemical reactions and pathways resulting in the breakdown of phytoene. go.json phytoene breakdown|phytoene catabolism|phytoene degradation http://purl.obolibrary.org/obo/GO_1901173 GO:1901170 biolink:BiologicalProcess naphthalene catabolic process The chemical reactions and pathways resulting in the breakdown of naphthalene. UM-BBD_pathwayID:naph go.json naphthalene breakdown|naphthalene metabolism|naphthalene metabolic process|naphthalene catabolism|naphthalene degradation http://purl.obolibrary.org/obo/GO_1901170 GO:1901171 biolink:BiologicalProcess obsolete naphthalene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of naphthalene. go.json naphthalene formation|naphthalene biosynthesis|naphthalene anabolism|naphthalene synthesis http://purl.obolibrary.org/obo/GO_1901171 GO:0061390 biolink:BiologicalProcess positive regulation of direction of cell growth Any process that increases the direction of cell growth. go.json http://purl.obolibrary.org/obo/GO_0061390 GO:0061391 biolink:BiologicalProcess negative regulation of direction of cell growth Any process that decreases the direction of cell growth. go.json http://purl.obolibrary.org/obo/GO_0061391 GO:0061392 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to osmotic stress OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go.json http://purl.obolibrary.org/obo/GO_0061392 GO:0061393 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go.json http://purl.obolibrary.org/obo/GO_0061393 GO:1901178 biolink:BiologicalProcess spheroidene metabolic process The chemical reactions and pathways involving spheroidene. go.json spheroidene metabolism http://purl.obolibrary.org/obo/GO_1901178 GO:0061394 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. go.json http://purl.obolibrary.org/obo/GO_0061394 GO:0061395 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. go.json http://purl.obolibrary.org/obo/GO_0061395 GO:1901179 biolink:BiologicalProcess spheroidene catabolic process The chemical reactions and pathways resulting in the breakdown of spheroidene. go.json spheroidene catabolism|spheroidene degradation|spheroidene breakdown http://purl.obolibrary.org/obo/GO_1901179 GO:1901176 biolink:BiologicalProcess lycopene catabolic process The chemical reactions and pathways resulting in the breakdown of lycopene. go.json lycopene breakdown|lycopene degradation|lycopene catabolism http://purl.obolibrary.org/obo/GO_1901176 GO:0061396 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. go.json http://purl.obolibrary.org/obo/GO_0061396 GO:1901177 biolink:BiologicalProcess lycopene biosynthetic process The chemical reactions and pathways resulting in the formation of lycopene. go.json lycopene biosynthesis|lycopene formation|lycopene anabolism|lycopene synthesis http://purl.obolibrary.org/obo/GO_1901177 GO:0061397 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to copper ion OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. go.json http://purl.obolibrary.org/obo/GO_0061397 GO:1901185 biolink:BiologicalProcess negative regulation of ERBB signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway. go.json down regulation of EGFR family signaling pathway|negative regulation of EGF receptor family signaling pathway|down regulation of ERBB signaling pathway|down-regulation of EGF receptor family signaling pathway|inhibition of ERBB signalling pathway|inhibition of ErbB signaling|inhibition of ERBB signaling pathway|downregulation of EGFR family signaling pathway|down-regulation of ERBB signaling pathway|down regulation of EGF receptor family signaling pathway|down-regulation of ERBB signalling pathway|negative regulation of ERBB signalling pathway|downregulation of ErbB signaling|downregulation of EGF receptor family signaling pathway|inhibition of EGFR family signaling pathway|down regulation of ERBB signalling pathway|down regulation of ErbB signaling|negative regulation of EGFR family signaling pathway|down-regulation of EGFR family signaling pathway|downregulation of ERBB signaling pathway|downregulation of ERBB signalling pathway|inhibition of EGF receptor family signaling pathway|down-regulation of ErbB signaling|negative regulation of ErbB signaling http://purl.obolibrary.org/obo/GO_1901185 GO:0061398 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter in response to copper ion OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. go.json http://purl.obolibrary.org/obo/GO_0061398 GO:1901186 biolink:BiologicalProcess positive regulation of ERBB signaling pathway Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway. go.json upregulation of ErbB signaling|up regulation of ERBB signalling pathway|upregulation of EGF receptor family signaling pathway|activation of EGF receptor family signaling pathway|positive regulation of ErbB signaling|positive regulation of ERBB signalling pathway|up-regulation of EGFR family signaling pathway|upregulation of ERBB signaling pathway|up regulation of ErbB signaling|up regulation of EGFR family signaling pathway|upregulation of ERBB signalling pathway|up-regulation of ErbB signaling|activation of ERBB signalling pathway|positive regulation of EGFR family signaling pathway|up-regulation of EGF receptor family signaling pathway|up regulation of ERBB signaling pathway|up regulation of EGF receptor family signaling pathway|upregulation of EGFR family signaling pathway|activation of ErbB signaling|activation of ERBB signaling pathway|up-regulation of ERBB signaling pathway|positive regulation of EGF receptor family signaling pathway|activation of EGFR family signaling pathway|up-regulation of ERBB signalling pathway http://purl.obolibrary.org/obo/GO_1901186 GO:0061399 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus. go.json http://purl.obolibrary.org/obo/GO_0061399 GO:1901183 biolink:BiologicalProcess positive regulation of camalexin biosynthetic process Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process. go.json up regulation of camalexin biosynthesis|up regulation of camalexin anabolism|up regulation of camalexin biosynthetic process|up-regulation of camalexin synthesis|positive regulation of camalexin anabolism|up-regulation of camalexin biosynthesis|up-regulation of camalexin biosynthetic process|activation of camalexin biosynthetic process|up regulation of camalexin synthesis|up-regulation of camalexin formation|upregulation of camalexin anabolism|positive regulation of camalexin synthesis|up regulation of camalexin formation|activation of camalexin anabolism|positive regulation of camalexin formation|activation of camalexin biosynthesis|upregulation of camalexin synthesis|upregulation of camalexin biosynthesis|upregulation of camalexin biosynthetic process|activation of camalexin synthesis|upregulation of camalexin formation|up-regulation of camalexin anabolism|positive regulation of camalexin biosynthesis|activation of camalexin formation http://purl.obolibrary.org/obo/GO_1901183 GO:1901184 biolink:BiologicalProcess regulation of ERBB signaling pathway Any process that modulates the frequency, rate or extent of ERBB signaling pathway. go.json regulation of EGFR family signaling pathway|regulation of EGF receptor family signaling pathway|regulation of ErbB signaling|regulation of ERBB signalling pathway http://purl.obolibrary.org/obo/GO_1901184 GO:1901181 biolink:BiologicalProcess negative regulation of cellular response to caffeine Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine. go.json inhibition of cellular response to caffeine|downregulation of cellular response to caffeine|down-regulation of cellular response to caffeine|down regulation of cellular response to caffeine http://purl.obolibrary.org/obo/GO_1901181 GO:1901182 biolink:BiologicalProcess regulation of camalexin biosynthetic process Any process that modulates the frequency, rate or extent of camalexin biosynthetic process. go.json regulation of camalexin synthesis|regulation of camalexin formation|regulation of camalexin biosynthesis|regulation of camalexin anabolism http://purl.obolibrary.org/obo/GO_1901182 GO:1901180 biolink:BiologicalProcess spheroidene biosynthetic process The chemical reactions and pathways resulting in the formation of spheroidene. go.json spheroidene biosynthesis|spheroidene anabolism|spheroidene synthesis|spheroidene formation http://purl.obolibrary.org/obo/GO_1901180 GO:1901189 biolink:BiologicalProcess positive regulation of ephrin receptor signaling pathway Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway. go.json up-regulation of Eph receptor signalling pathway|activation of Eph receptor signaling pathway|up regulation of Eph receptor signalling pathway|upregulation of Eph receptor signaling pathway|up-regulation of ephrin receptor signaling pathway|positive regulation of Eph receptor signalling pathway|up regulation of ephrin receptor signaling pathway|positive regulation of Eph receptor signaling pathway|activation of ephrin receptor signaling pathway|up regulation of Eph receptor signaling pathway|upregulation of Eph receptor signalling pathway|activation of Eph receptor signalling pathway|upregulation of ephrin receptor signaling pathway|up-regulation of Eph receptor signaling pathway http://purl.obolibrary.org/obo/GO_1901189 GO:1901187 biolink:BiologicalProcess regulation of ephrin receptor signaling pathway Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway. go.json regulation of Eph receptor signalling pathway|regulation of Eph receptor signaling pathway http://purl.obolibrary.org/obo/GO_1901187 GO:1901188 biolink:BiologicalProcess negative regulation of ephrin receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway. go.json down regulation of ephrin receptor signaling pathway|down regulation of Eph receptor signaling pathway|downregulation of Eph receptor signalling pathway|inhibition of ephrin receptor signaling pathway|downregulation of ephrin receptor signaling pathway|down-regulation of Eph receptor signaling pathway|negative regulation of Eph receptor signaling pathway|inhibition of Eph receptor signalling pathway|inhibition of Eph receptor signaling pathway|down-regulation of Eph receptor signalling pathway|negative regulation of Eph receptor signalling pathway|down regulation of Eph receptor signalling pathway|downregulation of Eph receptor signaling pathway|down-regulation of ephrin receptor signaling pathway http://purl.obolibrary.org/obo/GO_1901188 GO:1901196 biolink:BiologicalProcess positive regulation of calcium-mediated signaling involved in cellular response to salt stress Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress. go.json up-regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|activation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular salinity response|up regulation of calcium-mediated signaling involved in cellular response to salt stress|activation of calcium-mediated signaling involved in cellular response to salt stress|up regulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular response to salt stress|activation of calcium-mediated signaling involved in cellular salinity response|stimulation of calcium-mediated signaling involved in cellular response to salt stress|positive regulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular salinity response|stimulation of calcium-mediated signaling involved in cellular salinity response|upregulation of calcium-mediated signaling involved in cellular response to salt stress|upregulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|upregulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular response to ionic osmotic stress|positive regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|stimulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular response to salt stress http://purl.obolibrary.org/obo/GO_1901196 GO:1901197 biolink:BiologicalProcess positive regulation of calcium-mediated signaling involved in cellular response to calcium ion Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion. go.json stimulation of calcium-mediated signaling involved in cellular response to calcium ion|upregulation of calcium-mediated signaling involved in cellular response to calcium ion|upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up-regulation of calcium-mediated signaling involved in response to calcium ion|up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up regulation of calcium-mediated signaling involved in cellular response to calcium ion|up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|activation of calcium-mediated signaling involved in cellular response to Ca2+ ion|activation of calcium-mediated signaling involved in cellular response to calcium ion|positive regulation of calcium-mediated signalling involved in cellular response to calcium ion http://purl.obolibrary.org/obo/GO_1901197 GO:1901194 biolink:BiologicalProcess negative regulation of formation of translation preinitiation complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex. go.json down-regulation of formation of translation pre-initiation complex|negative regulation of formation of translation pre-initiation complex|inhibition of translation preinitiation complex assembly|down regulation of formation of translation pre-initiation complex|downregulation of translation preinitiation complex assembly|downregulation of formation of translation preinitiation complex|downregulation of formation of translation pre-initiation complex|down regulation of formation of translation preinitiation complex|down regulation of translation preinitiation complex assembly|inhibition of formation of translation pre-initiation complex|inhibition of formation of translation preinitiation complex|negative regulation of translation preinitiation complex assembly|down-regulation of formation of translation preinitiation complex|down-regulation of translation preinitiation complex assembly http://purl.obolibrary.org/obo/GO_1901194 GO:1901195 biolink:BiologicalProcess positive regulation of formation of translation preinitiation complex Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex. go.json upregulation of formation of translation pre-initiation complex|positive regulation of translation preinitiation complex assembly|activation of formation of translation pre-initiation complex|up regulation of formation of translation preinitiation complex|up regulation of translation preinitiation complex assembly|up-regulation of translation preinitiation complex assembly|up-regulation of formation of translation preinitiation complex|up-regulation of formation of translation pre-initiation complex|activation of formation of translation preinitiation complex|up regulation of formation of translation pre-initiation complex|positive regulation of formation of translation pre-initiation complex|activation of translation preinitiation complex assembly|upregulation of translation preinitiation complex assembly|upregulation of formation of translation preinitiation complex http://purl.obolibrary.org/obo/GO_1901195 GO:1901192 biolink:BiologicalProcess positive regulation of formation of translation initiation ternary complex Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. go.json activation of translation initiation ternary complex assembly|up-regulation of formation of translation initiation ternary complex|up-regulation of translation initiation ternary complex assembly|up regulation of translation initiation ternary complex assembly|up regulation of formation of translation initiation ternary complex|positive regulation of translation initiation ternary complex assembly|activation of formation of translation initiation ternary complex|upregulation of formation of translation initiation ternary complex|upregulation of translation initiation ternary complex assembly http://purl.obolibrary.org/obo/GO_1901192 GO:1901193 biolink:BiologicalProcess regulation of formation of translation preinitiation complex Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex. go.json regulation of formation of translation pre-initiation complex|regulation of translation preinitiation complex assembly http://purl.obolibrary.org/obo/GO_1901193 GO:1901190 biolink:BiologicalProcess regulation of formation of translation initiation ternary complex Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. go.json regulation of translation initiation ternary complex assembly http://purl.obolibrary.org/obo/GO_1901190 GO:1901191 biolink:BiologicalProcess negative regulation of formation of translation initiation ternary complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. go.json down regulation of formation of translation initiation ternary complex|down regulation of translation initiation ternary complex assembly|inhibition of formation of translation initiation ternary complex|downregulation of translation initiation ternary complex assembly|downregulation of formation of translation initiation ternary complex|inhibition of translation initiation ternary complex assembly|down-regulation of formation of translation initiation ternary complex|negative regulation of translation initiation ternary complex assembly|down-regulation of translation initiation ternary complex assembly http://purl.obolibrary.org/obo/GO_1901191 GO:1901198 biolink:BiologicalProcess positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion. go.json positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion http://purl.obolibrary.org/obo/GO_1901198 GO:1901199 biolink:BiologicalProcess positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress. go.json positive regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress|positive regulation of calcium ion transport into cytosol involved in cellular salinity response http://purl.obolibrary.org/obo/GO_1901199 GO:0051995 biolink:MolecularActivity Se-methyltransferase activity Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule. go.json http://purl.obolibrary.org/obo/GO_0051995 GO:0051996 biolink:MolecularActivity squalene synthase activity Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate. EC:2.5.1.21|MetaCyc:RXN66-281 go.json squalene synthetase activity http://purl.obolibrary.org/obo/GO_0051996 GO:0051993 biolink:MolecularActivity abscisic acid glucose ester beta-glucosidase activity Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose. RHEA:31347|MetaCyc:RXN-11469|EC:3.2.1.175 go.json ABA-GE beta-glucosidase activity http://purl.obolibrary.org/obo/GO_0051993 GO:0051994 biolink:MolecularActivity P-methyltransferase activity Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule. EC:2.1.1.- go.json http://purl.obolibrary.org/obo/GO_0051994 GO:0051999 biolink:BiologicalProcess mannosyl-inositol phosphorylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative. go.json mannose inositol phosphoceramide biosynthetic process|MIPC biosynthetic process|mannosyl-inositol phosphorylceramide anabolism|mannosyl-inositol phosphorylceramide synthesis|mannosyl-inositol phosphorylceramide biosynthesis|mannosyl-inositol phosphorylceramide formation|mannose-inositol-P-ceramide (MIPC) biosynthetic process http://purl.obolibrary.org/obo/GO_0051999 GO:0051997 biolink:MolecularActivity 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2. KEGG_REACTION:R06604|RHEA:26301|MetaCyc:RXN-6201 go.json OHCU decarboxylase activity|4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity http://purl.obolibrary.org/obo/GO_0051997 GO:0051998 biolink:MolecularActivity protein carboxyl O-methyltransferase activity Catalysis of the transfer of a methyl group to a carboxyl group on a protein. go.json protein carboxyl methyltransferase activity http://purl.obolibrary.org/obo/GO_0051998 GO:2000104 biolink:BiologicalProcess negative regulation of DNA-dependent DNA replication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication. go.json http://purl.obolibrary.org/obo/GO_2000104 GO:2000105 biolink:BiologicalProcess positive regulation of DNA-dependent DNA replication Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication. go.json http://purl.obolibrary.org/obo/GO_2000105 GO:2000106 biolink:BiologicalProcess regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of leukocyte apoptotic process. go.json regulation of leukocyte apoptosis http://purl.obolibrary.org/obo/GO_2000106 GO:2000107 biolink:BiologicalProcess negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. go.json negative regulation of leukocyte apoptosis http://purl.obolibrary.org/obo/GO_2000107 GO:2000108 biolink:BiologicalProcess positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. go.json positive regulation of leukocyte apoptosis http://purl.obolibrary.org/obo/GO_2000108 GO:2000109 biolink:BiologicalProcess regulation of macrophage apoptotic process Any process that modulates the frequency, rate or extent of macrophage apoptotic process. go.json regulation of activation-induced cell death|regulation of AICD|regulation of macrophage apoptosis http://purl.obolibrary.org/obo/GO_2000109 GO:0061320 biolink:BiologicalProcess pericardial nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go.json pericardial cell differentiation http://purl.obolibrary.org/obo/GO_0061320 GO:0036354 biolink:MolecularActivity 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+. RHEA:19733|MetaCyc:RXN-8787 go.json http://purl.obolibrary.org/obo/GO_0036354 GO:0061321 biolink:BiologicalProcess garland nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go.json garland cell differentiation http://purl.obolibrary.org/obo/GO_0061321 GO:0036355 biolink:MolecularActivity 2-iminoacetate synthase activity Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+. MetaCyc:RXN-11319|EC:4.1.99.19|RHEA:26361 go.json http://purl.obolibrary.org/obo/GO_0036355 GO:0061322 biolink:BiologicalProcess disseminated nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061322 GO:0036356 biolink:MolecularActivity cyclic 2,3-diphosphoglycerate synthetase activity Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate. EC:4.6.1.- go.json cDPGS activity|CPGS activity http://purl.obolibrary.org/obo/GO_0036356 GO:0061323 biolink:BiologicalProcess cell proliferation involved in heart morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. go.json http://purl.obolibrary.org/obo/GO_0061323 GO:0061324 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells. go.json canonical Wnt-activated signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of cardiac outflow tract cell proliferation http://purl.obolibrary.org/obo/GO_0061324 GO:0036357 biolink:MolecularActivity 2-phosphoglycerate kinase activity Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP. EC:2.7.2.- go.json 2PGK activity http://purl.obolibrary.org/obo/GO_0036357 GO:0061325 biolink:BiologicalProcess cell proliferation involved in outflow tract morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. go.json http://purl.obolibrary.org/obo/GO_0061325 GO:2000100 biolink:BiologicalProcess regulation of establishment or maintenance of bipolar cell polarity regulating cell shape Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape. go.json http://purl.obolibrary.org/obo/GO_2000100 GO:0036358 biolink:BiologicalProcess lipoteichoic acid D-alanylation The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA). go.json D-alanyl lipoteichoic acid formation|D-alanyl LTA formation|LTA D-alanylation http://purl.obolibrary.org/obo/GO_0036358 GO:2000101 biolink:BiologicalProcess regulation of mammary stem cell proliferation Any process that modulates the frequency, rate or extent of mammary stem cell proliferation. go.json http://purl.obolibrary.org/obo/GO_2000101 GO:0061326 biolink:BiologicalProcess renal tubule development The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. go.json http://purl.obolibrary.org/obo/GO_0061326 GO:0036359 biolink:BiologicalProcess renal potassium excretion The elimination by an organism of potassium in the urine. go.json renal K+ elimination|renal K(+) excretion|renal potassium ion excretion http://purl.obolibrary.org/obo/GO_0036359 GO:2000102 biolink:BiologicalProcess negative regulation of mammary stem cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation. go.json http://purl.obolibrary.org/obo/GO_2000102 GO:0061327 biolink:BiologicalProcess anterior Malpighian tubule development The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. go.json http://purl.obolibrary.org/obo/GO_0061327 GO:0061328 biolink:BiologicalProcess posterior Malpighian tubule development The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. go.json http://purl.obolibrary.org/obo/GO_0061328 GO:2000103 biolink:BiologicalProcess positive regulation of mammary stem cell proliferation Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation. go.json http://purl.obolibrary.org/obo/GO_2000103 GO:0061329 biolink:BiologicalProcess Malpighian tubule principal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule. go.json http://purl.obolibrary.org/obo/GO_0061329 GO:0051991 biolink:MolecularActivity UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP. EC:2.4.1.227|MetaCyc:NACGLCTRANS-RXN|RHEA:31227 go.json http://purl.obolibrary.org/obo/GO_0051991 GO:0036350 biolink:BiologicalProcess mannose-specific flocculation The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other. go.json cell-cell adhesion involved in mannose-specific flocculation http://purl.obolibrary.org/obo/GO_0036350 GO:0036351 biolink:BiologicalProcess histone H2A-K13 ubiquitination The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin. go.json histone H2A ubiquitination (H2A-K13) http://purl.obolibrary.org/obo/GO_0036351 GO:0051992 biolink:MolecularActivity UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol. EC:2.7.8.13|MetaCyc:PHOSNACMURPENTATRANS-RXN|RHEA:28386 go.json http://purl.obolibrary.org/obo/GO_0051992 goslim_chembl GO:0036352 biolink:BiologicalProcess histone H2A-K15 ubiquitination The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin. go.json histone H2A ubiquitination (H2A-K15) http://purl.obolibrary.org/obo/GO_0036352 GO:0036353 biolink:BiologicalProcess histone H2A-K119 monoubiquitination The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms. go.json histone H2A monoubiquitination (H2A-K119) http://purl.obolibrary.org/obo/GO_0036353 GO:0051990 biolink:MolecularActivity (R)-2-hydroxyglutarate dehydrogenase activity Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. Reactome:R-HSA-880053|RHEA:38295|Reactome:R-HSA-880007|EC:1.1.99.39 go.json D-2-hydroxyglutarate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0051990 GO:2000115 biolink:BiologicalProcess regulation of maintenance of bipolar cell polarity regulating cell shape Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape. go.json http://purl.obolibrary.org/obo/GO_2000115 GO:2000116 biolink:BiologicalProcess regulation of cysteine-type endopeptidase activity Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity. go.json regulation of lysosomal cysteine-type endopeptidase|regulation of thiol endopeptidase activity http://purl.obolibrary.org/obo/GO_2000116 GO:2000117 biolink:BiologicalProcess negative regulation of cysteine-type endopeptidase activity Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity. go.json negative regulation of thiol endopeptidase activity|negative regulation of lysosomal cysteine-type endopeptidase http://purl.obolibrary.org/obo/GO_2000117 GO:2000118 biolink:BiologicalProcess regulation of sodium-dependent phosphate transport Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport. go.json http://purl.obolibrary.org/obo/GO_2000118 GO:2000119 biolink:BiologicalProcess negative regulation of sodium-dependent phosphate transport Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport. go.json http://purl.obolibrary.org/obo/GO_2000119 GO:0061310 biolink:BiologicalProcess canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation. go.json canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt-activated signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt receptor signalling pathway involved in cardiac neural crest cell differentiation involved in heart development http://purl.obolibrary.org/obo/GO_0061310 GO:0036343 biolink:BiologicalProcess psychomotor behavior The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument. go.json http://purl.obolibrary.org/obo/GO_0036343 GO:0061311 biolink:BiologicalProcess cell surface receptor signaling pathway involved in heart development Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time. go.json cell surface receptor linked signaling pathway involved in heart development|cell surface receptor linked signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061311 GO:0036344 biolink:BiologicalProcess platelet morphogenesis Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. go.json http://purl.obolibrary.org/obo/GO_0036344 GO:0061312 biolink:BiologicalProcess BMP signaling pathway involved in heart development A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time. go.json BMP signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061312 GO:0036345 biolink:BiologicalProcess platelet maturation A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. go.json http://purl.obolibrary.org/obo/GO_0036345 GO:0061313 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in heart development The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time. go.json fibroblast growth factor receptor signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061313 GO:0036346 biolink:BiologicalProcess cellular response to L-cysteine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration. go.json http://purl.obolibrary.org/obo/GO_0036346 GO:2000110 biolink:BiologicalProcess negative regulation of macrophage apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process. go.json negative regulation of AICD|negative regulation of activation-induced cell death|negative regulation of macrophage apoptosis http://purl.obolibrary.org/obo/GO_2000110 GO:2000111 biolink:BiologicalProcess positive regulation of macrophage apoptotic process Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process. go.json positive regulation of macrophage apoptosis|positive regulation of activation-induced cell death|positive regulation of AICD http://purl.obolibrary.org/obo/GO_2000111 GO:0061314 biolink:BiologicalProcess Notch signaling involved in heart development The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time. go.json Notch signalling involved in heart development http://purl.obolibrary.org/obo/GO_0061314 GO:0036347 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036347 GO:0061315 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells. go.json canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0061315 GO:0036348 biolink:MolecularActivity hydantoin racemase activity Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin. MetaCyc:RXN-9781|RHEA:46624|KEGG_REACTION:R09704|EC:5.1.99.5 go.json http://purl.obolibrary.org/obo/GO_0036348 GO:2000112 biolink:BiologicalProcess regulation of cellular macromolecule biosynthetic process Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process. go.json regulation of cellular macromolecule anabolism|regulation of cellular biopolymer biosynthetic process|regulation of cellular macromolecule synthesis|regulation of cellular macromolecule formation|regulation of cellular macromolecule biosynthesis http://purl.obolibrary.org/obo/GO_2000112 GO:0061316 biolink:BiologicalProcess canonical Wnt signaling pathway involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go.json canonical Wnt-activated signaling pathway involved in heart development|canonical Wnt receptor signalling pathway involved in heart development|canonical Wnt receptor signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061316 GO:0036349 biolink:BiologicalProcess galactose-specific flocculation The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other. go.json cell-cell adhesion involved in galactose-specific flocculation http://purl.obolibrary.org/obo/GO_0036349 GO:2000113 biolink:BiologicalProcess negative regulation of cellular macromolecule biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process. go.json negative regulation of cellular macromolecule biosynthesis|negative regulation of cellular macromolecule anabolism|negative regulation of cellular biopolymer biosynthetic process|negative regulation of cellular macromolecule synthesis|negative regulation of cellular macromolecule formation http://purl.obolibrary.org/obo/GO_2000113 GO:0061317 biolink:BiologicalProcess canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go.json canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment http://purl.obolibrary.org/obo/GO_0061317 GO:2000114 biolink:BiologicalProcess regulation of establishment of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity. go.json regulation of bud site selection/establishment of cell polarity|regulation of cell polarization http://purl.obolibrary.org/obo/GO_2000114 GO:0061318 biolink:BiologicalProcess renal filtration cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061318 GO:0061319 biolink:BiologicalProcess nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go.json http://purl.obolibrary.org/obo/GO_0061319 GO:0036340 biolink:BiologicalProcess chitin-based cuticle sclerotization by biomineralization The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate. go.json chitin-based cuticle hardening by biomineralisation http://purl.obolibrary.org/obo/GO_0036340 GO:0036341 biolink:BiologicalProcess chitin-based cuticle sclerotization by protein cross-linking The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle. go.json chitin-based cuticle sclerotization by protein cross-linking and cuticle tanning http://purl.obolibrary.org/obo/GO_0036341 GO:0036342 biolink:BiologicalProcess post-anal tail morphogenesis The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. go.json http://purl.obolibrary.org/obo/GO_0036342 GO:1901109 biolink:BiologicalProcess granaticin biosynthetic process The chemical reactions and pathways resulting in the formation of granaticin. go.json granaticin biosynthesis|granaticin anabolism|granaticin synthesis|granaticin formation http://purl.obolibrary.org/obo/GO_1901109 GO:1901107 biolink:BiologicalProcess granaticin metabolic process The chemical reactions and pathways involving granaticin. go.json granaticin metabolism http://purl.obolibrary.org/obo/GO_1901107 GO:1901108 biolink:BiologicalProcess granaticin catabolic process The chemical reactions and pathways resulting in the breakdown of granaticin. go.json granaticin catabolism|granaticin degradation|granaticin breakdown http://purl.obolibrary.org/obo/GO_1901108 GO:1901105 biolink:BiologicalProcess tetracenomycin C catabolic process The chemical reactions and pathways resulting in the breakdown of tetracenomycin C. go.json tetracenomycin C degradation|tetracenomycin C breakdown|tetracenomycin C catabolism http://purl.obolibrary.org/obo/GO_1901105 GO:2000126 biolink:BiologicalProcess negative regulation of octopamine or tyramine signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway. go.json negative regulation of octopamine/tyramine signaling pathway|negative regulation of octopamine or tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000126 GO:1901106 biolink:BiologicalProcess tetracenomycin C biosynthetic process The chemical reactions and pathways resulting in the formation of tetracenomycin C. go.json tetracenomycin C biosynthesis|tetracenomycin C anabolism|tetracenomycin C synthesis|tetracenomycin C formation http://purl.obolibrary.org/obo/GO_1901106 GO:2000127 biolink:BiologicalProcess positive regulation of octopamine or tyramine signaling pathway Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway. go.json positive regulation of octopamine or tyramine signalling pathway|positive regulation of octopamine/tyramine signaling pathway http://purl.obolibrary.org/obo/GO_2000127 GO:1901103 biolink:BiologicalProcess gramicidin S biosynthetic process The chemical reactions and pathways resulting in the formation of gramicidin S. go.json gramicidin S anabolism|gramicidin S biosynthesis|gramicidin S synthesis|gramicidin S formation http://purl.obolibrary.org/obo/GO_1901103 GO:2000128 biolink:BiologicalProcess regulation of octopamine signaling pathway Any process that modulates the frequency, rate or extent of octopamine signaling pathway. go.json regulation of octopamine signalling pathway http://purl.obolibrary.org/obo/GO_2000128 GO:2000129 biolink:BiologicalProcess negative regulation of octopamine signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway. go.json negative regulation of octopamine signalling pathway http://purl.obolibrary.org/obo/GO_2000129 GO:1901104 biolink:BiologicalProcess tetracenomycin C metabolic process The chemical reactions and pathways involving tetracenomycin C. go.json tetracenomycin C metabolism http://purl.obolibrary.org/obo/GO_1901104 GO:1901101 biolink:BiologicalProcess gramicidin S metabolic process The chemical reactions and pathways involving gramicidin S. go.json gramicidin S metabolism http://purl.obolibrary.org/obo/GO_1901101 GO:0061340 biolink:BiologicalProcess establishment or maintenance of monopolar cell polarity regulating cell shape Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell. go.json http://purl.obolibrary.org/obo/GO_0061340 GO:1901102 biolink:BiologicalProcess gramicidin S catabolic process The chemical reactions and pathways resulting in the breakdown of gramicidin S. go.json gramicidin S catabolism|gramicidin S degradation|gramicidin S breakdown http://purl.obolibrary.org/obo/GO_1901102 GO:0061341 biolink:BiologicalProcess non-canonical Wnt signaling pathway involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time. go.json non-canonical Wnt receptor signalling pathway involved in heart development|non-canonical Wnt receptor signaling pathway involved in heart development|non-canonical Wnt-activated signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061341 GO:0061342 biolink:BiologicalProcess regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart. go.json regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signalling pathway http://purl.obolibrary.org/obo/GO_0061342 GO:0036332 biolink:MolecularActivity placental growth factor-activated receptor activity Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity. go.json PlGF receptor activity|placental growth factor receptor activity|PlGF-activated receptor activity http://purl.obolibrary.org/obo/GO_0036332 GO:0061343 biolink:BiologicalProcess cell adhesion involved in heart morphogenesis The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. go.json http://purl.obolibrary.org/obo/GO_0061343 GO:0061344 biolink:BiologicalProcess regulation of cell adhesion involved in heart morphogenesis Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. go.json http://purl.obolibrary.org/obo/GO_0061344 GO:0036333 biolink:BiologicalProcess hepatocyte homeostasis Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. go.json http://purl.obolibrary.org/obo/GO_0036333 GO:2000120 biolink:BiologicalProcess positive regulation of sodium-dependent phosphate transport Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport. go.json http://purl.obolibrary.org/obo/GO_2000120 GO:0036334 biolink:BiologicalProcess epidermal stem cell homeostasis Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells. go.json http://purl.obolibrary.org/obo/GO_0036334 GO:0061345 biolink:BiologicalProcess planar cell polarity pathway involved in cardiac muscle cell fate commitment The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate. go.json http://purl.obolibrary.org/obo/GO_0061345 GO:0061346 biolink:BiologicalProcess planar cell polarity pathway involved in heart morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart. go.json http://purl.obolibrary.org/obo/GO_0061346 GO:2000121 biolink:BiologicalProcess regulation of removal of superoxide radicals Any process that modulates the frequency, rate or extent of removal of superoxide radicals. go.json regulation of removal of oxygen free radicals|regulation of removal of O2- http://purl.obolibrary.org/obo/GO_2000121 GO:0036335 biolink:BiologicalProcess intestinal stem cell homeostasis Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells. go.json http://purl.obolibrary.org/obo/GO_0036335 GO:0061347 biolink:BiologicalProcess planar cell polarity pathway involved in outflow tract morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract. go.json http://purl.obolibrary.org/obo/GO_0061347 GO:2000122 biolink:BiologicalProcess negative regulation of stomatal complex development Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development. go.json http://purl.obolibrary.org/obo/GO_2000122 GO:0036336 biolink:BiologicalProcess dendritic cell migration The movement of a dendritic cell within or between different tissues and organs of the body. go.json http://purl.obolibrary.org/obo/GO_0036336 GO:0061348 biolink:BiologicalProcess planar cell polarity pathway involved in ventricular septum morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum. go.json http://purl.obolibrary.org/obo/GO_0061348 GO:0036337 biolink:BiologicalProcess Fas signaling pathway A series of molecular signals initiated by the binding of a ligand to the receptor Fas on the surface of the cell, and ending with regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily. go.json FasR signaling pathway|FAS ligand-Fas signaling pathway|Apo-1 signaling pathway|Fas receptor signaling pathway|Fas-FasL signaling pathway|CD95 signaling pathway|FasL signaling pathway http://purl.obolibrary.org/obo/GO_0036337 GO:2000123 biolink:BiologicalProcess positive regulation of stomatal complex development Any process that activates or increases the frequency, rate or extent of stomatal complex development. go.json http://purl.obolibrary.org/obo/GO_2000123 GO:2000124 biolink:BiologicalProcess regulation of endocannabinoid signaling pathway Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway. go.json regulation of endocannabinoid signalling pathway http://purl.obolibrary.org/obo/GO_2000124 GO:0061349 biolink:BiologicalProcess planar cell polarity pathway involved in cardiac right atrium morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium. go.json http://purl.obolibrary.org/obo/GO_0061349 GO:0036338 biolink:CellularComponent viral membrane The lipid bilayer of a virion, a complete fully infectious extracellular virus particle. go.json http://purl.obolibrary.org/obo/GO_0036338 GO:2000125 biolink:BiologicalProcess regulation of octopamine or tyramine signaling pathway Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway. go.json regulation of octopamine/tyramine signaling pathway|regulation of octopamine or tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000125 GO:0036339 biolink:BiologicalProcess lymphocyte adhesion to endothelial cell of high endothelial venule The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream. go.json lymphocyte adhesion to high endothelial venule|lymphocyte adhesion to HEV cell http://purl.obolibrary.org/obo/GO_0036339 GO:0036330 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036330 GO:0036331 biolink:BiologicalProcess avascular cornea development in camera-type eye The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees. go.json avascular cornea development http://purl.obolibrary.org/obo/GO_0036331 GO:1901118 biolink:BiologicalProcess cephamycin C biosynthetic process The chemical reactions and pathways resulting in the formation of cephamycin C. go.json cephamycin C anabolism|cephamycin C synthesis|cephamycin C formation|cephamycin C biosynthesis http://purl.obolibrary.org/obo/GO_1901118 GO:1901119 biolink:BiologicalProcess tobramycin metabolic process The chemical reactions and pathways involving tobramycin. go.json tobramycin metabolism http://purl.obolibrary.org/obo/GO_1901119 GO:1901116 biolink:BiologicalProcess cephamycin C metabolic process The chemical reactions and pathways involving cephamycin C. go.json cephamycin C metabolism http://purl.obolibrary.org/obo/GO_1901116 GO:2000137 biolink:BiologicalProcess negative regulation of cell proliferation involved in heart morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000137 GO:0036329 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036329 GO:1901117 biolink:BiologicalProcess cephamycin C catabolic process The chemical reactions and pathways resulting in the breakdown of cephamycin C. go.json cephamycin C degradation|cephamycin C breakdown|cephamycin C catabolism http://purl.obolibrary.org/obo/GO_1901117 GO:2000138 biolink:BiologicalProcess positive regulation of cell proliferation involved in heart morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000138 GO:1901114 biolink:BiologicalProcess erythromycin catabolic process The chemical reactions and pathways resulting in the breakdown of erythromycin. go.json erythromycin breakdown|erythromycin catabolism|erythromycin degradation http://purl.obolibrary.org/obo/GO_1901114 GO:2000139 biolink:BiologicalProcess regulation of octopamine signaling pathway involved in response to food Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food. go.json regulation of octopamine signalling pathway involved in response to food http://purl.obolibrary.org/obo/GO_2000139 GO:1901115 biolink:BiologicalProcess erythromycin biosynthetic process The chemical reactions and pathways resulting in the formation of erythromycin. go.json erythromycin formation|erythromycin biosynthesis|erythromycin anabolism|erythromycin synthesis http://purl.obolibrary.org/obo/GO_1901115 GO:1901112 biolink:BiologicalProcess actinorhodin biosynthetic process The chemical reactions and pathways resulting in the formation of actinorhodin. go.json actinorhodin anabolism|actinorhodin synthesis|actinorhodin formation|actinorhodin biosynthesis http://purl.obolibrary.org/obo/GO_1901112 GO:1901113 biolink:BiologicalProcess erythromycin metabolic process The chemical reactions and pathways involving erythromycin. go.json erythromycin metabolism http://purl.obolibrary.org/obo/GO_1901113 GO:1901110 biolink:BiologicalProcess actinorhodin metabolic process The chemical reactions and pathways involving actinorhodin. go.json actinorhodin metabolism http://purl.obolibrary.org/obo/GO_1901110 GO:0061330 biolink:BiologicalProcess Malpighian tubule stellate cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. go.json http://purl.obolibrary.org/obo/GO_0061330 GO:1901111 biolink:BiologicalProcess actinorhodin catabolic process The chemical reactions and pathways resulting in the breakdown of actinorhodin. go.json actinorhodin degradation|actinorhodin breakdown|actinorhodin catabolism http://purl.obolibrary.org/obo/GO_1901111 GO:0061331 biolink:BiologicalProcess epithelial cell proliferation involved in Malpighian tubule morphogenesis The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. go.json http://purl.obolibrary.org/obo/GO_0061331 GO:0061332 biolink:BiologicalProcess Malpighian tubule bud morphogenesis The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. go.json Malpighian tubule formation http://purl.obolibrary.org/obo/GO_0061332 GO:0036321 biolink:BiologicalProcess ghrelin secretion The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone. go.json pancreatic ghrelin secretion http://purl.obolibrary.org/obo/GO_0036321 GO:0061333 biolink:BiologicalProcess renal tubule morphogenesis The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. go.json http://purl.obolibrary.org/obo/GO_0061333 GO:1901120 biolink:BiologicalProcess tobramycin catabolic process The chemical reactions and pathways resulting in the breakdown of tobramycin. go.json tobramycin degradation|tobramycin catabolism|tobramycin breakdown http://purl.obolibrary.org/obo/GO_1901120 GO:0036322 biolink:BiologicalProcess pancreatic polypeptide secretion The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas. go.json PP secretion http://purl.obolibrary.org/obo/GO_0036322 GO:2000130 biolink:BiologicalProcess positive regulation of octopamine signaling pathway Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway. go.json positive regulation of octopamine signalling pathway http://purl.obolibrary.org/obo/GO_2000130 GO:0061334 biolink:BiologicalProcess cell rearrangement involved in Malpighian tubule morphogenesis The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. go.json cell migration involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061334 GO:0036323 biolink:BiologicalProcess vascular endothelial growth factor receptor-1 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-1 (VEGFR-1) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go.json VEGFR1 signaling pathway|VEGFR-1 signaling pathway|FLT1 signaling pathway http://purl.obolibrary.org/obo/GO_0036323 GO:2000131 biolink:BiologicalProcess regulation of tyramine signaling pathway Any process that modulates the frequency, rate or extent of tyramine signaling pathway. go.json regulation of tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000131 GO:0036324 biolink:BiologicalProcess vascular endothelial growth factor receptor-2 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go.json VEGFR-2 signaling pathway|VEGFR2 signaling pathway|FLK-1 signaling pathway|KDR signaling pathway http://purl.obolibrary.org/obo/GO_0036324 GO:0061335 biolink:BiologicalProcess cell growth involved in Malpighian tubule morphogenesis The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule. go.json http://purl.obolibrary.org/obo/GO_0061335 GO:2000132 biolink:BiologicalProcess negative regulation of tyramine signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway. go.json negative regulation of tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000132 GO:0061336 biolink:BiologicalProcess cell morphogenesis involved in Malpighian tubule morphogenesis The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. go.json http://purl.obolibrary.org/obo/GO_0061336 GO:2000133 biolink:BiologicalProcess positive regulation of tyramine signaling pathway Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway. go.json positive regulation of tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000133 GO:0036325 biolink:BiologicalProcess vascular endothelial growth factor receptor-3 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-3 (VEGFR-3) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go.json VEGFR3 signaling pathway|VEGFR-3 signaling pathway|FLT4 signaling pathway http://purl.obolibrary.org/obo/GO_0036325 GO:0061337 biolink:BiologicalProcess cardiac conduction Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. go.json http://purl.obolibrary.org/obo/GO_0061337 GO:2000134 biolink:BiologicalProcess negative regulation of G1/S transition of mitotic cell cycle Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. go.json http://purl.obolibrary.org/obo/GO_2000134 GO:0036326 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036326 GO:2000135 biolink:BiologicalProcess obsolete positive regulation of regulation of secondary heart field cardioblast proliferation OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of secondary heart field cardioblast proliferation. go.json positive regulation of regulation of secondary heart field cardioblast proliferation|positive regulation of regulation of second heart field cardioblast proliferation http://purl.obolibrary.org/obo/GO_2000135 GO:0061338 biolink:BiologicalProcess obsolete atrioventricular node impulse conduction delay OBSOLETE. A heart process that modulates the propagation of the signal that causes the heart muscle to contract. go.json atrioventricular node impulse conduction delay http://purl.obolibrary.org/obo/GO_0061338 GO:0036327 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036327 GO:0061339 biolink:BiologicalProcess establishment or maintenance of monopolar cell polarity Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. go.json http://purl.obolibrary.org/obo/GO_0061339 GO:0036328 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0036328 GO:2000136 biolink:BiologicalProcess regulation of cell proliferation involved in heart morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000136 GO:0036320 biolink:MolecularActivity mating-type P-factor pheromone receptor activity Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus. go.json P-factor receptor activity|P-factor mating pheromone receptor activity http://purl.obolibrary.org/obo/GO_0036320 GO:1901129 biolink:BiologicalProcess gentamycin catabolic process The chemical reactions and pathways resulting in the breakdown of gentamycin. go.json gentamycin breakdown|gentamycin catabolism|gentamycin degradation http://purl.obolibrary.org/obo/GO_1901129 GO:1901127 biolink:BiologicalProcess candicidin biosynthetic process The chemical reactions and pathways resulting in the formation of candicidin. go.json candicidin formation|candicidin biosynthesis|candicidin anabolism|candicidin synthesis http://purl.obolibrary.org/obo/GO_1901127 GO:0036318 biolink:MolecularActivity peptide pheromone receptor activity Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity. go.json http://purl.obolibrary.org/obo/GO_0036318 GO:0036319 biolink:MolecularActivity mating-type M-factor pheromone receptor activity Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus. go.json M-factor mating pheromone receptor activity|M-factor receptor activity http://purl.obolibrary.org/obo/GO_0036319 GO:1901128 biolink:BiologicalProcess gentamycin metabolic process The chemical reactions and pathways involving gentamycin. go.json gentamycin metabolism http://purl.obolibrary.org/obo/GO_1901128 GO:1901125 biolink:BiologicalProcess candicidin metabolic process The chemical reactions and pathways involving candicidin. go.json candicidin metabolism http://purl.obolibrary.org/obo/GO_1901125 GO:1901126 biolink:BiologicalProcess candicidin catabolic process The chemical reactions and pathways resulting in the breakdown of candicidin. go.json candicidin breakdown|candicidin degradation|candicidin catabolism http://purl.obolibrary.org/obo/GO_1901126 GO:0061360 biolink:BiologicalProcess optic chiasma development The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. go.json optic chiasm development http://purl.obolibrary.org/obo/GO_0061360 GO:1901123 biolink:BiologicalProcess bacitracin A catabolic process The chemical reactions and pathways resulting in the breakdown of bacitracin A. go.json bacitracin A breakdown|bacitracin A catabolism|bacitracin A degradation http://purl.obolibrary.org/obo/GO_1901123 GO:0061361 biolink:BiologicalProcess positive regulation of maintenance of bipolar cell polarity regulating cell shape Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. go.json http://purl.obolibrary.org/obo/GO_0061361 GO:1901124 biolink:BiologicalProcess bacitracin A biosynthetic process The chemical reactions and pathways resulting in the formation of bacitracin A. go.json bacitracin A synthesis|bacitracin A formation|bacitracin A anabolism|bacitracin A biosynthesis http://purl.obolibrary.org/obo/GO_1901124 GO:0061362 biolink:BiologicalProcess negative regulation of maintenance of bipolar cell polarity regulating cell shape Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. go.json http://purl.obolibrary.org/obo/GO_0061362 GO:1901121 biolink:BiologicalProcess tobramycin biosynthetic process The chemical reactions and pathways resulting in the formation of tobramycin. go.json tobramycin anabolism|tobramycin synthesis|tobramycin formation|tobramycin biosynthesis http://purl.obolibrary.org/obo/GO_1901121 GO:0061363 biolink:BiologicalProcess negative regulation of progesterone biosynthesis involved in luteolysis Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis. go.json functional luteolysis http://purl.obolibrary.org/obo/GO_0061363 GO:1901122 biolink:BiologicalProcess bacitracin A metabolic process The chemical reactions and pathways involving bacitracin A. go.json bacitracin A metabolism http://purl.obolibrary.org/obo/GO_1901122 GO:0061364 biolink:BiologicalProcess apoptotic process involved in luteolysis The apoptotic process that contributes to luteolysis. go.json structural luteolysis|apoptosis involved in luteolysis http://purl.obolibrary.org/obo/GO_0061364 GO:0061365 biolink:BiologicalProcess positive regulation of triglyceride lipase activity Any process that increases the activity of triglyceride lipase. go.json positive regulation of TAG activity http://purl.obolibrary.org/obo/GO_0061365 GO:1901130 biolink:BiologicalProcess gentamycin biosynthetic process The chemical reactions and pathways resulting in the formation of gentamycin. go.json gentamycin anabolism|gentamycin synthesis|gentamycin formation|gentamycin biosynthesis http://purl.obolibrary.org/obo/GO_1901130 GO:0036310 biolink:MolecularActivity annealing helicase activity Catalysis of the ATP-dependent rewinding of single-stranded DNA (ssDNA) to reform base pairs between strands. Often acts on ssDNA bubbles bound by replication protein A (RPA). go.json nucleoside-triphosphatase activity involved in DNA annealing|ATP-dependent DNA annealing activity|annealing activity http://purl.obolibrary.org/obo/GO_0036310 GO:0061366 biolink:BiologicalProcess behavioral response to chemical pain Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus. go.json http://purl.obolibrary.org/obo/GO_0061366 GO:0036311 biolink:MolecularActivity chitin disaccharide deacetylase activity Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate. go.json chitin oligosaccharide amidohydrolase activity|chitobiose amidohydrolase activity|chitin oligosaccharide deacetylase activity http://purl.obolibrary.org/obo/GO_0036311 GO:1901131 biolink:BiologicalProcess kanamycin metabolic process The chemical reactions and pathways involving kanamycin. go.json kanamycin metabolism http://purl.obolibrary.org/obo/GO_1901131 GO:0061367 biolink:BiologicalProcess behavioral response to acetic acid induced pain Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus. go.json http://purl.obolibrary.org/obo/GO_0061367 GO:0036312 biolink:MolecularActivity phosphatidylinositol 3-kinase regulatory subunit binding Interacting selectively and non-covalently with a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location. go.json p85 binding|PI3K regulatory subunit binding http://purl.obolibrary.org/obo/GO_0036312 GO:0036313 biolink:MolecularActivity phosphatidylinositol 3-kinase catalytic subunit binding Interacting selectively and non-covalently with the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring. go.json p110 binding|PI3K catalytic subunit binding http://purl.obolibrary.org/obo/GO_0036313 GO:0061368 biolink:BiologicalProcess behavioral response to formalin induced pain Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus. go.json http://purl.obolibrary.org/obo/GO_0061368 GO:0061369 biolink:BiologicalProcess negative regulation of testicular blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle. go.json negative regulation of testicular vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0061369 GO:0036314 biolink:BiologicalProcess response to sterol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. go.json http://purl.obolibrary.org/obo/GO_0036314 GO:0036315 biolink:BiologicalProcess cellular response to sterol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. go.json http://purl.obolibrary.org/obo/GO_0036315 GO:0036316 biolink:BiologicalProcess SREBP-SCAP complex retention in endoplasmic reticulum Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER. go.json http://purl.obolibrary.org/obo/GO_0036316 GO:0036317 biolink:MolecularActivity tyrosyl-RNA phosphodiesterase activity Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis. go.json unlinkase activity|VPg unlinkase activity|uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity|Y-pUpN PDE activity http://purl.obolibrary.org/obo/GO_0036317 GO:0036307 biolink:MolecularActivity 23S rRNA (adenine(2030)-N(6))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA. go.json http://purl.obolibrary.org/obo/GO_0036307 GO:1901138 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_1901138 GO:0036308 biolink:MolecularActivity 16S rRNA (guanine(1516)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine. go.json http://purl.obolibrary.org/obo/GO_0036308 GO:1901139 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_1901139 GO:1901136 biolink:BiologicalProcess carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. go.json carbohydrate derivative degradation|carbohydrate derivative catabolism|carbohydrate derivative breakdown http://purl.obolibrary.org/obo/GO_1901136 GO:0036309 biolink:BiologicalProcess protein localization to M-band Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere. go.json protein localization to M line|cellular protein localization to M-band|protein localization to mesophragma|protein localization to M disc http://purl.obolibrary.org/obo/GO_0036309 GO:1901137 biolink:BiologicalProcess carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. go.json carbohydrate derivative anabolism|carbohydrate derivative synthesis|carbohydrate derivative biosynthesis|carbohydrate derivative formation http://purl.obolibrary.org/obo/GO_1901137 GO:0061350 biolink:BiologicalProcess planar cell polarity pathway involved in cardiac muscle tissue morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue. go.json http://purl.obolibrary.org/obo/GO_0061350 GO:1901134 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_1901134 GO:0061351 biolink:BiologicalProcess neural precursor cell proliferation The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. go.json http://purl.obolibrary.org/obo/GO_0061351 GO:1901135 biolink:BiologicalProcess carbohydrate derivative metabolic process The chemical reactions and pathways involving carbohydrate derivative. go.json carbohydrate derivative metabolism http://purl.obolibrary.org/obo/GO_1901135 goslim_agr|goslim_mouse GO:1901132 biolink:BiologicalProcess kanamycin catabolic process The chemical reactions and pathways resulting in the breakdown of kanamycin. go.json kanamycin catabolism|kanamycin degradation|kanamycin breakdown http://purl.obolibrary.org/obo/GO_1901132 GO:0061352 biolink:BiologicalProcess cell chemotaxis involved in Malpighian tubule morphogenesis The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule. go.json http://purl.obolibrary.org/obo/GO_0061352 GO:1901133 biolink:BiologicalProcess kanamycin biosynthetic process The chemical reactions and pathways resulting in the formation of kanamycin. go.json kanamycin anabolism|kanamycin biosynthesis|kanamycin synthesis|kanamycin formation http://purl.obolibrary.org/obo/GO_1901133 GO:0061353 biolink:BiologicalProcess BMP signaling pathway involved in Malpighian tubule cell chemotaxis A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule. go.json bone morphogenic protein receptor signalling pathway involved in Malpighian tubule cell chemotaxis http://purl.obolibrary.org/obo/GO_0061353 GO:1901141 biolink:BiologicalProcess regulation of lignin biosynthetic process Any process that modulates the frequency, rate or extent of lignin biosynthetic process. go.json regulation of lignin anabolism|regulation of lignin synthesis|regulation of lignin biosynthesis|regulation of lignin formation http://purl.obolibrary.org/obo/GO_1901141 GO:0061354 biolink:BiologicalProcess planar cell polarity pathway involved in pericardium morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium. go.json http://purl.obolibrary.org/obo/GO_0061354 GO:0036300 biolink:BiologicalProcess B cell receptor internalization A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell. go.json B cell receptor uptake of antigen|BCR endocytosis|BCR receptor internalization http://purl.obolibrary.org/obo/GO_0036300 GO:1901142 biolink:BiologicalProcess insulin metabolic process The chemical reactions and pathways involving insulin. go.json insulin metabolism http://purl.obolibrary.org/obo/GO_1901142 GO:0061355 biolink:BiologicalProcess Wnt protein secretion The controlled release of a Wnt protein from a cell. go.json http://purl.obolibrary.org/obo/GO_0061355 GO:0036301 biolink:BiologicalProcess macrophage colony-stimulating factor production The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go.json M-CSF production http://purl.obolibrary.org/obo/GO_0036301 gocheck_do_not_annotate GO:0061356 biolink:BiologicalProcess regulation of Wnt protein secretion Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell. go.json http://purl.obolibrary.org/obo/GO_0061356 GO:0036302 biolink:BiologicalProcess atrioventricular canal development The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle. go.json http://purl.obolibrary.org/obo/GO_0036302 GO:0061357 biolink:BiologicalProcess positive regulation of Wnt protein secretion Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell. go.json http://purl.obolibrary.org/obo/GO_0061357 GO:1901140 biolink:BiologicalProcess p-coumaryl alcohol transport The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json 4-hydroxycinnamyl alcohol transport http://purl.obolibrary.org/obo/GO_1901140 GO:0061358 biolink:BiologicalProcess negative regulation of Wnt protein secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell. go.json http://purl.obolibrary.org/obo/GO_0061358 GO:0036303 biolink:BiologicalProcess lymph vessel morphogenesis The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. go.json http://purl.obolibrary.org/obo/GO_0036303 GO:0061359 biolink:BiologicalProcess regulation of Wnt signaling pathway by Wnt protein secretion Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell. go.json regulation of Wnt receptor signaling pathway by Wnt protein secretion|regulation of Wnt receptor signalling pathway by Wnt protein secretion|regulation of Wnt-activated signaling pathway by Wnt protein secretion http://purl.obolibrary.org/obo/GO_0061359 GO:0036304 biolink:BiologicalProcess umbilical cord morphogenesis The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. go.json http://purl.obolibrary.org/obo/GO_0036304 GO:0036305 biolink:BiologicalProcess ameloblast differentiation The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. go.json http://purl.obolibrary.org/obo/GO_0036305 GO:0036306 biolink:BiologicalProcess embryonic heart tube elongation The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. go.json http://purl.obolibrary.org/obo/GO_0036306 GO:1901149 biolink:MolecularActivity salicylic acid binding Interacting selectively and non-covalently with salicylic acid. go.json salicylic acid receptor http://purl.obolibrary.org/obo/GO_1901149 GO:0061380 biolink:BiologicalProcess superior colliculus development The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain. go.json http://purl.obolibrary.org/obo/GO_0061380 GO:0061381 biolink:BiologicalProcess cell migration in diencephalon The orderly movement of a cell that will reside in the diencephalon. go.json http://purl.obolibrary.org/obo/GO_0061381 GO:1901147 biolink:BiologicalProcess mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis. go.json http://purl.obolibrary.org/obo/GO_1901147 GO:1901148 biolink:BiologicalProcess gene expression involved in extracellular matrix organization Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. go.json expression of extracellular matrix proteins|extracellular matrix protein production http://purl.obolibrary.org/obo/GO_1901148 GO:0061382 biolink:BiologicalProcess Malpighian tubule tip cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells. go.json http://purl.obolibrary.org/obo/GO_0061382 GO:1901145 biolink:BiologicalProcess mesenchymal cell apoptotic process involved in nephron morphogenesis Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis. go.json http://purl.obolibrary.org/obo/GO_1901145 GO:0061383 biolink:BiologicalProcess trabecula morphogenesis The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. go.json http://purl.obolibrary.org/obo/GO_0061383 GO:1901146 biolink:BiologicalProcess mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis. go.json http://purl.obolibrary.org/obo/GO_1901146 GO:0061384 biolink:BiologicalProcess heart trabecula morphogenesis The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. go.json http://purl.obolibrary.org/obo/GO_0061384 GO:1901143 biolink:BiologicalProcess insulin catabolic process The chemical reactions and pathways resulting in the breakdown of insulin. go.json insulin breakdown|insulin catabolism|insulin degradation http://purl.obolibrary.org/obo/GO_1901143 GO:0061385 biolink:BiologicalProcess fibroblast proliferation involved in heart morphogenesis The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. go.json http://purl.obolibrary.org/obo/GO_0061385 GO:1901144 biolink:BiologicalProcess obsolete insulin biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of insulin. go.json insulin formation|insulin anabolism|insulin biosynthesis|insulin biosynthetic process|insulin synthesis http://purl.obolibrary.org/obo/GO_1901144 GO:0061386 biolink:BiologicalProcess closure of optic fissure The closure of the temporary ventral gap in the optic cup that contributes to its shaping. go.json closure or choriod fissure http://purl.obolibrary.org/obo/GO_0061386 GO:1901152 biolink:BiologicalProcess vistamycin biosynthetic process The chemical reactions and pathways resulting in the formation of vistamycin. go.json vistamycin anabolism|ribostamycin synthesis|vistamycin synthesis|ribostamycin formation|vistamycin formation|ribostamycin biosynthetic process|ribostamycin biosynthesis|vistamycin biosynthesis|ribostamycin anabolism http://purl.obolibrary.org/obo/GO_1901152 GO:0061387 biolink:BiologicalProcess regulation of extent of cell growth Any process that modulates the extent of cell growth. go.json http://purl.obolibrary.org/obo/GO_0061387 GO:0061388 biolink:BiologicalProcess regulation of rate of cell growth Any process that modulates the rate of cell growth. go.json http://purl.obolibrary.org/obo/GO_0061388 GO:1901153 biolink:BiologicalProcess paromomycin metabolic process The chemical reactions and pathways involving paromomycin. go.json paromomycin metabolism http://purl.obolibrary.org/obo/GO_1901153 GO:1901150 biolink:BiologicalProcess vistamycin metabolic process The chemical reactions and pathways involving vistamycin. go.json ribostamycin metabolic process|ribostamycin metabolism|vistamycin metabolism http://purl.obolibrary.org/obo/GO_1901150 GO:0061389 biolink:BiologicalProcess regulation of direction of cell growth Any process that modulates the direction of cell growth. go.json http://purl.obolibrary.org/obo/GO_0061389 GO:1901151 biolink:BiologicalProcess vistamycin catabolic process The chemical reactions and pathways resulting in the breakdown of vistamycin. go.json ribostamycin degradation|vistamycin degradation|ribostamycin breakdown|ribostamycin catabolism|vistamycin catabolism|vistamycin breakdown|ribostamycin catabolic process http://purl.obolibrary.org/obo/GO_1901151 GO:1901158 biolink:BiologicalProcess neomycin biosynthetic process The chemical reactions and pathways resulting in the formation of neomycin. go.json neomycin synthesis|neomycin biosynthesis|neomycin formation|neomycin anabolism http://purl.obolibrary.org/obo/GO_1901158 GO:0061370 biolink:BiologicalProcess testosterone biosynthetic process The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5. go.json http://purl.obolibrary.org/obo/GO_0061370 GO:0061371 biolink:BiologicalProcess determination of heart left/right asymmetry Determination of the asymmetric location of the heart with respect to the left and right halves of the organism. go.json determination of cardiac left/right asymmetry http://purl.obolibrary.org/obo/GO_0061371 GO:1901159 biolink:BiologicalProcess xylulose 5-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate. go.json xylulose 5-phosphate synthesis|xylulose 5-phosphate biosynthesis|xylulose 5-phosphate formation|xylulose 5-phosphate anabolism http://purl.obolibrary.org/obo/GO_1901159 GO:0061372 biolink:BiologicalProcess activin receptor signaling pathway involved in heart jogging A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging. go.json activin receptor signalling pathway involved in heart jogging http://purl.obolibrary.org/obo/GO_0061372 GO:1901156 biolink:BiologicalProcess neomycin metabolic process The chemical reactions and pathways involving neomycin. go.json neomycin metabolism http://purl.obolibrary.org/obo/GO_1901156 GO:1901157 biolink:BiologicalProcess neomycin catabolic process The chemical reactions and pathways resulting in the breakdown of neomycin. go.json neomycin catabolism|neomycin degradation|neomycin breakdown http://purl.obolibrary.org/obo/GO_1901157 GO:0061373 biolink:BiologicalProcess mammillary axonal complex development The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain. go.json http://purl.obolibrary.org/obo/GO_0061373 GO:1901154 biolink:BiologicalProcess paromomycin catabolic process The chemical reactions and pathways resulting in the breakdown of paromomycin. go.json paromomycin catabolism|paromomycin degradation|paromomycin breakdown http://purl.obolibrary.org/obo/GO_1901154 GO:0061374 biolink:BiologicalProcess mammillothalamic axonal tract development The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit. go.json http://purl.obolibrary.org/obo/GO_0061374 GO:0061375 biolink:BiologicalProcess mammillotectal axonal tract development The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. go.json http://purl.obolibrary.org/obo/GO_0061375 GO:1901155 biolink:BiologicalProcess paromomycin biosynthetic process The chemical reactions and pathways resulting in the formation of paromomycin. go.json paromomycin anabolism|paromomycin biosynthesis|paromomycin synthesis|paromomycin formation http://purl.obolibrary.org/obo/GO_1901155 GO:1901163 biolink:BiologicalProcess regulation of trophoblast cell migration Any process that modulates the frequency, rate or extent of trophoblast cell migration. go.json http://purl.obolibrary.org/obo/GO_1901163 GO:0061376 biolink:BiologicalProcess mammillotegmental axonal tract development The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons. go.json http://purl.obolibrary.org/obo/GO_0061376 GO:0061377 biolink:BiologicalProcess mammary gland lobule development The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. go.json http://purl.obolibrary.org/obo/GO_0061377 GO:1901164 biolink:BiologicalProcess negative regulation of trophoblast cell migration Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. go.json downregulation of trophoblast cell migration|down regulation of trophoblast cell migration|inhibition of trophoblast cell migration|down-regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_1901164 GO:1901161 biolink:BiologicalProcess primary amino compound catabolic process The chemical reactions and pathways resulting in the breakdown of primary amino compound. go.json primary amino compound catabolism|primary amino compound degradation|primary amino compound breakdown http://purl.obolibrary.org/obo/GO_1901161 GO:0061378 biolink:BiologicalProcess corpora quadrigemina development The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi. go.json http://purl.obolibrary.org/obo/GO_0061378 GO:1901162 biolink:BiologicalProcess primary amino compound biosynthetic process The chemical reactions and pathways resulting in the formation of primary amino compound. go.json primary amino compound anabolism|primary amino compound biosynthesis|primary amino compound synthesis|primary amino compound formation http://purl.obolibrary.org/obo/GO_1901162 GO:0061379 biolink:BiologicalProcess inferior colliculus development The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally. go.json http://purl.obolibrary.org/obo/GO_0061379 GO:1901160 biolink:BiologicalProcess primary amino compound metabolic process The chemical reactions and pathways involving primary amino compound. go.json primary amino compound metabolism http://purl.obolibrary.org/obo/GO_1901160 GO:0051911 biolink:MolecularActivity Methanosarcina-phenazine hydrogenase activity Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine. EC:1.12.98.3|MetaCyc:RXN-7733|RHEA:24436 go.json methylviologen-reducing hydrogenase activity|methanophenazine hydrogenase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051911 GO:0051912 biolink:MolecularActivity CoB--CoM heterodisulfide reductase activity Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine. MetaCyc:1.8.98.1-RXN|EC:1.8.98.1|RHEA:18085 go.json coenzyme B--coenzyme M heterodisulfide reductase activity|CoB-CoM heterodisulfide reductase activity|soluble heterodisulfide reductase activity|heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|coenzyme B:coenzyme M:methanophenazine oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051912 GO:0051910 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_0051910 GO:0051915 biolink:BiologicalProcess induction of synaptic plasticity by chemical substance The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require. go.json induction of synaptic plasticity by drug|activation of synaptic plasticity by drug|activation of synaptic plasticity by chemical substance http://purl.obolibrary.org/obo/GO_0051915 GO:0051916 biolink:MolecularActivity granulocyte colony-stimulating factor binding Interacting selectively and non-covalently with granulocyte colony-stimulating factor, G-CSF. go.json granulocyte colony stimulating factor binding|G-CSF binding http://purl.obolibrary.org/obo/GO_0051916 GO:0051913 biolink:BiologicalProcess regulation of synaptic plasticity by chemical substance The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require. go.json regulation of synaptic plasticity by drug http://purl.obolibrary.org/obo/GO_0051913 GO:0051914 biolink:BiologicalProcess positive regulation of synaptic plasticity by chemical substance The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require. go.json up-regulation of synaptic plasticity by chemical substance|positive regulation of synaptic plasticity by drug|up regulation of synaptic plasticity by chemical substance|activation of synaptic plasticity by chemical substance|stimulation of synaptic plasticity by chemical substance|upregulation of synaptic plasticity by chemical substance http://purl.obolibrary.org/obo/GO_0051914 GO:0051919 biolink:BiologicalProcess positive regulation of fibrinolysis Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. go.json up-regulation of fibrinolysis|activation of fibrinolysis|upregulation of fibrinolysis|stimulation of fibrinolysis|up regulation of fibrinolysis http://purl.obolibrary.org/obo/GO_0051919 GO:0051917 biolink:BiologicalProcess regulation of fibrinolysis Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. go.json http://purl.obolibrary.org/obo/GO_0051917 GO:0051918 biolink:BiologicalProcess negative regulation of fibrinolysis Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. go.json downregulation of fibrinolysis|down regulation of fibrinolysis|inhibition of fibrinolysis|down-regulation of fibrinolysis http://purl.obolibrary.org/obo/GO_0051918 GO:2000184 biolink:BiologicalProcess positive regulation of progesterone biosynthetic process Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. go.json positive regulation of progesterone synthesis|positive regulation of progesterone formation|positive regulation of progesterone biosynthesis|positive regulation of progesterone anabolism http://purl.obolibrary.org/obo/GO_2000184 GO:2000185 biolink:BiologicalProcess regulation of phosphate transmembrane transport Any process that modulates the frequency, rate or extent of phosphate transmembrane transport. go.json regulation of phosphate membrane transport http://purl.obolibrary.org/obo/GO_2000185 GO:2000186 biolink:BiologicalProcess negative regulation of phosphate transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport. go.json negative regulation of phosphate membrane transport http://purl.obolibrary.org/obo/GO_2000186 GO:2000187 biolink:BiologicalProcess positive regulation of phosphate transmembrane transport Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport. go.json positive regulation of phosphate membrane transport http://purl.obolibrary.org/obo/GO_2000187 GO:2000188 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_2000188 GO:2000189 biolink:OntologyClass go.json http://purl.obolibrary.org/obo/GO_2000189 GO:2000180 biolink:BiologicalProcess negative regulation of androgen biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process. go.json negative regulation of androgen formation|negative regulation of androgen biosynthesis|negative regulation of androgen anabolism|negative regulation of androgen synthesis http://purl.obolibrary.org/obo/GO_2000180 GO:2000181 biolink:BiologicalProcess negative regulation of blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000181 GO:2000182 biolink:BiologicalProcess regulation of progesterone biosynthetic process Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. go.json regulation of progesterone biosynthesis|regulation of progesterone anabolism|regulation of progesterone synthesis|regulation of progesterone formation http://purl.obolibrary.org/obo/GO_2000182 GO:2000183 biolink:BiologicalProcess negative regulation of progesterone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process. go.json negative regulation of progesterone formation|negative regulation of progesterone anabolism|negative regulation of progesterone biosynthesis|negative regulation of progesterone synthesis http://purl.obolibrary.org/obo/GO_2000183 GO:0051922 biolink:MolecularActivity cholesterol sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate. EC:2.8.2.- go.json http://purl.obolibrary.org/obo/GO_0051922 GO:0051923 biolink:BiologicalProcess sulfation The addition of a sulfate group to a molecule. go.json sulfonation|phase II metabolism|sulfur addition|sulphation|sulphur addition http://purl.obolibrary.org/obo/GO_0051923 GO:0051920 biolink:MolecularActivity peroxiredoxin activity Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. Reactome:R-HSA-1222431|EC:1.11.1.24|Reactome:R-HSA-1500804|RHEA:10008|Reactome:R-HSA-1222755|MetaCyc:1.11.1.15-RXN go.json PRDX activity|Prx activity|alkyl hydroperoxide reductase C22 activity|AhpC activity|thiol-containing-reductant:hydroperoxide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051920 GO:0051921 biolink:MolecularActivity adenosylcobyric acid synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate. EC:6.3.5.10|MetaCyc:R345-RXN|RHEA:23256|KEGG_REACTION:R05225 go.json Ado-cobyric acid synthase [glutamine hydrolyzing] activity|CobQ activity|cobyric acid synthase activity|5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity|adenosylcobyric acid synthase (glutamine-hydrolysing) activity|adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0051921 GO:0051926 biolink:BiologicalProcess negative regulation of calcium ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json down regulation of calcium ion transport|inhibition of calcium ion transport|downregulation of calcium ion transport|negative regulation of calcium transport|down-regulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0051926 GO:0051927 biolink:BiologicalProcess obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel. go.json inhibition of calcium ion transport via voltage gated calcium channel|downregulation of calcium ion transport via voltage gated calcium channel|negative regulation of calcium ion transport via voltage-gated calcium channel activity|negative regulation of calcium transport via voltage gated calcium channel|down-regulation of calcium ion transport via voltage gated calcium channel|down regulation of calcium ion transport via voltage gated calcium channel http://purl.obolibrary.org/obo/GO_0051927 GO:0051924 biolink:BiologicalProcess regulation of calcium ion transport Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json regulation of calcium transport http://purl.obolibrary.org/obo/GO_0051924 GO:0051925 biolink:BiologicalProcess obsolete regulation of calcium ion transport via voltage-gated calcium channel activity OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel. go.json regulation of calcium transport via voltage-gated calcium channel|regulation of calcium ion transport via voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0051925 GO:0051928 biolink:BiologicalProcess positive regulation of calcium ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json positive regulation of calcium transport|up-regulation of calcium ion transport|up regulation of calcium ion transport|activation of calcium ion transport|stimulation of calcium ion transport|upregulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0051928 GO:0051929 biolink:BiologicalProcess obsolete positive regulation of calcium ion transport via voltage-gated calcium channel activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via the activity of voltage-gated calcium channels. go.json up-regulation of calcium ion transport via voltage gated calcium channel|up regulation of calcium ion transport via voltage gated calcium channel|activation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium ion transport via voltage-gated calcium channel activity|stimulation of calcium ion transport via voltage gated calcium channel|upregulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium transport via voltage gated calcium channel http://purl.obolibrary.org/obo/GO_0051929 GO:2000195 biolink:BiologicalProcess negative regulation of female gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. go.json negative regulation of ovarian development|negative regulation of ovary development http://purl.obolibrary.org/obo/GO_2000195 GO:2000196 biolink:BiologicalProcess positive regulation of female gonad development Any process that activates or increases the frequency, rate or extent of female gonad development. go.json positive regulation of ovary development|positive regulation of ovarian development http://purl.obolibrary.org/obo/GO_2000196 GO:2000197 biolink:BiologicalProcess regulation of ribonucleoprotein complex localization Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization. go.json regulation of establishment and maintenance of ribonucleoprotein complex localization|regulation of ribonucleoprotein complex localisation|regulation of RNP localization|regulation of cellular ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000197 GO:2000198 biolink:BiologicalProcess negative regulation of ribonucleoprotein complex localization Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization. go.json negative regulation of cellular ribonucleoprotein complex localization|negative regulation of ribonucleoprotein complex localisation|negative regulation of RNP localization|negative regulation of establishment and maintenance of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000198 GO:2000199 biolink:BiologicalProcess positive regulation of ribonucleoprotein complex localization Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization. go.json positive regulation of establishment and maintenance of ribonucleoprotein complex localization|positive regulation of cellular ribonucleoprotein complex localization|positive regulation of RNP localization|positive regulation of ribonucleoprotein complex localisation http://purl.obolibrary.org/obo/GO_2000199 GO:2000190 biolink:BiologicalProcess obsolete negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor. go.json negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor http://purl.obolibrary.org/obo/GO_2000190 GO:2000191 biolink:BiologicalProcess regulation of fatty acid transport Any process that modulates the frequency, rate or extent of fatty acid transport. go.json http://purl.obolibrary.org/obo/GO_2000191 GO:2000192 biolink:BiologicalProcess negative regulation of fatty acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport. go.json http://purl.obolibrary.org/obo/GO_2000192 GO:2000193 biolink:BiologicalProcess positive regulation of fatty acid transport Any process that activates or increases the frequency, rate or extent of fatty acid transport. go.json http://purl.obolibrary.org/obo/GO_2000193 GO:2000194 biolink:BiologicalProcess regulation of female gonad development Any process that modulates the frequency, rate or extent of female gonad development. go.json regulation of ovary development|regulation of ovarian development http://purl.obolibrary.org/obo/GO_2000194 GO:0051930 biolink:BiologicalProcess regulation of sensory perception of pain Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. go.json http://purl.obolibrary.org/obo/GO_0051930 GO:0051933 biolink:BiologicalProcess amino acid neurotransmitter reuptake The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go.json amino acid uptake during transmission of nerve impulse|amino acid neurotransmitter import into neuron|amino acid neurotransmitter import into glial cell|amino acid neurotransmitter recycling http://purl.obolibrary.org/obo/GO_0051933 GO:0051934 biolink:BiologicalProcess catecholamine uptake involved in synaptic transmission The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go.json catecholamine neurotransmitter recycling|catecholamine neurotransmitter reuptake|catecholamine reuptake during transmission of nerve impulse|catecholamine neurotransmitter import into neuron|catecholamine neurotransmitter import into glial cell|catecholamine uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051934 GO:0051931 biolink:BiologicalProcess regulation of sensory perception Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. go.json http://purl.obolibrary.org/obo/GO_0051931 GO:0051932 biolink:BiologicalProcess synaptic transmission, GABAergic The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go.json GABAergic synaptic transmission|synaptic transmission, gamma-aminobutyric acid-ergic|synaptic transmission, GABA mediated|synaptic transmission, gamma-aminobutyric acid mediated http://purl.obolibrary.org/obo/GO_0051932 GO:0051937 biolink:BiologicalProcess catecholamine transport The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. go.json http://purl.obolibrary.org/obo/GO_0051937 GO:0051938 biolink:BiologicalProcess L-glutamate import The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle. go.json L-glutamate uptake http://purl.obolibrary.org/obo/GO_0051938 GO:0051935 biolink:BiologicalProcess glutamate reuptake The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go.json glutamate uptake during transmission of nerve impulse|glutamate recycling|L-glutamate reuptake|L-glutamate uptake during transmission of nerve impulse|L-glutamate uptake involved in synaptic transmission|glutamate import into glial cell|glutamate import into neuron http://purl.obolibrary.org/obo/GO_0051935 GO:0051936 biolink:BiologicalProcess gamma-aminobutyric acid reuptake The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go.json gamma-aminobutyric acid uptake during transmission of nerve impulse|gamma-aminobutyric acid recycling|GABA import into neuron|GABA import into glial cell|GABA recycling|gamma-aminobutyric acid uptake involved in synaptic transmission|gamma-aminobutyric acid import into neuron|GABA reuptake|gamma-aminobutyric acid import into glial cell http://purl.obolibrary.org/obo/GO_0051936 GO:0051939 biolink:BiologicalProcess gamma-aminobutyric acid import The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. go.json gamma-aminobutyric acid uptake|GABA import|4-aminobutyrate import|gamma-aminobutyrate import http://purl.obolibrary.org/obo/GO_0051939 GO:0051940 biolink:BiologicalProcess regulation of catecholamine uptake involved in synaptic transmission Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. go.json regulation of catecholamine uptake during transmission of nerve impulse|regulation of catecholamine neurotransmitter reuptake|regulation of catecholamine neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0051940 GO:0051941 biolink:BiologicalProcess regulation of amino acid uptake involved in synaptic transmission Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. go.json regulation of amino acid neurotransmitter reuptake|regulation of amino acid neurotransmitter uptake|regulation of amino acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051941 GO:0051944 biolink:BiologicalProcess positive regulation of catecholamine uptake involved in synaptic transmission Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. go.json stimulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine neurotransmitter reuptake|upregulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine neurotransmitter uptake|up-regulation of catecholamine uptake during transmission of nerve impulse|up regulation of catecholamine uptake during transmission of nerve impulse|activation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051944 GO:0051945 biolink:BiologicalProcess negative regulation of catecholamine uptake involved in synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. go.json negative regulation of catecholamine uptake during transmission of nerve impulse|down-regulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine neurotransmitter reuptake|down regulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine neurotransmitter uptake|inhibition of catecholamine uptake during transmission of nerve impulse|downregulation of catecholamine uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051945 GO:0051942 biolink:BiologicalProcess negative regulation of amino acid uptake involved in synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. go.json inhibition of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid uptake during transmission of nerve impulse|downregulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter reuptake|down regulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter uptake|down-regulation of amino acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051942 GO:0051943 biolink:BiologicalProcess positive regulation of amino acid uptake involved in synaptic transmission Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. go.json stimulation of amino acid uptake during transmission of nerve impulse|positive regulation of amino acid neurotransmitter uptake|up regulation of amino acid uptake during transmission of nerve impulse|up-regulation of amino acid uptake during transmission of nerve impulse|activation of amino acid uptake during transmission of nerve impulse|upregulation of amino acid uptake during transmission of nerve impulse|positive regulation of amino acid neurotransmitter reuptake http://purl.obolibrary.org/obo/GO_0051943 GO:0051948 biolink:BiologicalProcess negative regulation of glutamate uptake involved in transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. go.json down-regulation of glutamate uptake during transmission of nerve impulse|down regulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate reuptake|inhibition of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake involved in conduction of nerve impulse|downregulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051948 GO:0051949 biolink:BiologicalProcess negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. go.json negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of GABA uptake during transmission of nerve impulse|negative regulation of 4-aminobutyrate reuptake|negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid reuptake|down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of 4-aminobutyrate uptake during transmission of nerve impulse|negative regulation of GABA reuptake|downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|inhibition of gamma-aminobutyric acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051949 GO:0051946 biolink:BiologicalProcess regulation of glutamate uptake involved in transmission of nerve impulse Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. go.json regulation of glutamate uptake involved in conduction of nerve impulse|regulation of glutamate uptake during transmission of nerve impulse|regulation of L-glutamate reuptake|regulation of glutamate reuptake|regulation of L-glutamate uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051946 GO:0051947 biolink:BiologicalProcess regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. go.json regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|regulation of GABA reuptake|regulation of gamma-aminobutyric acid reuptake|regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|regulation of GABA uptake during transmission of nerve impulse|regulation of 4-aminobutyrate uptake during transmission of nerve impulse|regulation of 4-aminobutyrate reuptake http://purl.obolibrary.org/obo/GO_0051947 GO:0051951 biolink:BiologicalProcess positive regulation of glutamate uptake involved in transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. go.json positive regulation of glutamate uptake during transmission of nerve impulse|up-regulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate uptake involved in conduction of nerve impulse|positive regulation of glutamate reuptake|up regulation of glutamate uptake during transmission of nerve impulse|activation of glutamate uptake during transmission of nerve impulse|stimulation of glutamate uptake during transmission of nerve impulse|upregulation of glutamate uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051951 GO:0051952 biolink:BiologicalProcess regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json http://purl.obolibrary.org/obo/GO_0051952 GO:0051950 biolink:BiologicalProcess positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. go.json positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse|upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of GABA uptake during transmission of nerve impulse|positive regulation of GABA reuptake|positive regulation of 4-aminobutyrate reuptake|positive regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|positive regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of gamma-aminobutyric acid reuptake|up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|activation of gamma-aminobutyric acid uptake during transmission of nerve impulse|stimulation of gamma-aminobutyric acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051950 GO:0051955 biolink:BiologicalProcess regulation of amino acid transport Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json http://purl.obolibrary.org/obo/GO_0051955 GO:0051956 biolink:BiologicalProcess negative regulation of amino acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json down-regulation of amino acid transport|negative regulation of amino acid transmembrane transport|downregulation of amino acid transport|down regulation of amino acid transport|inhibition of amino acid transport http://purl.obolibrary.org/obo/GO_0051956 GO:0051953 biolink:BiologicalProcess negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json down-regulation of amine transport|down regulation of amine transport|downregulation of amine transport|inhibition of amine transport http://purl.obolibrary.org/obo/GO_0051953 GO:0051954 biolink:BiologicalProcess positive regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json up regulation of amine transport|activation of amine transport|stimulation of amine transport|upregulation of amine transport|up-regulation of amine transport http://purl.obolibrary.org/obo/GO_0051954 GO:0051959 biolink:MolecularActivity dynein light intermediate chain binding Interacting selectively and non-covalently with a light intermediate chain of the dynein complex. go.json http://purl.obolibrary.org/obo/GO_0051959 GO:2000148 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in ventricular septum morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000148 GO:2000149 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000149 GO:0051957 biolink:BiologicalProcess positive regulation of amino acid transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go.json upregulation of amino acid transport|up regulation of amino acid transport|stimulation of amino acid transport|up-regulation of amino acid transport|activation of amino acid transport|positive regulation of amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0051957 GO:0051958 biolink:BiologicalProcess methotrexate transport The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase. go.json http://purl.obolibrary.org/obo/GO_0051958 GO:0036398 biolink:CellularComponent TCR signalosome A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology. go.json linker for activation of T cells signalosome|LAT signalosome http://purl.obolibrary.org/obo/GO_0036398 GO:2000140 biolink:BiologicalProcess negative regulation of octopamine signaling pathway involved in response to food Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food. go.json negative regulation of octopamine signalling pathway involved in response to food http://purl.obolibrary.org/obo/GO_2000140 GO:0036399 biolink:BiologicalProcess TCR signalosome assembly The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome. go.json LAT signalosome assembly|linker for activation of T cells signalosome assembly http://purl.obolibrary.org/obo/GO_0036399 GO:2000141 biolink:BiologicalProcess positive regulation of octopamine signaling pathway involved in response to food Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food. go.json positive regulation of octopamine signalling pathway involved in response to food http://purl.obolibrary.org/obo/GO_2000141 GO:2000142 biolink:BiologicalProcess regulation of DNA-templated transcription, initiation Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation. go.json regulation of DNA-dependent transcription, initiation|regulation of transcription initiation, DNA-dependent|regulation of initiation of DNA-dependent transcription http://purl.obolibrary.org/obo/GO_2000142 GO:2000143 biolink:BiologicalProcess negative regulation of DNA-templated transcription, initiation Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation. go.json negative regulation of initiation of DNA-dependent transcription|negative regulation of DNA-dependent transcription, initiation|negative regulation of transcription initiation, DNA-dependent http://purl.obolibrary.org/obo/GO_2000143 GO:2000144 biolink:BiologicalProcess positive regulation of DNA-templated transcription, initiation Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation. go.json positive regulation of DNA-dependent transcription, initiation|transcriptional transactivation|positive regulation of transcription initiation, DNA-dependent|transactivation|positive regulation of initiation of DNA-dependent transcription http://purl.obolibrary.org/obo/GO_2000144 GO:2000145 biolink:BiologicalProcess regulation of cell motility Any process that modulates the frequency, rate or extent of cell motility. go.json regulation of cell movement|regulation of cell locomotion|regulation of movement of a cell http://purl.obolibrary.org/obo/GO_2000145 GO:2000146 biolink:BiologicalProcess negative regulation of cell motility Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. go.json negative regulation of cell locomotion|negative regulation of cell movement|negative regulation of movement of a cell http://purl.obolibrary.org/obo/GO_2000146 GO:2000147 biolink:BiologicalProcess positive regulation of cell motility Any process that activates or increases the frequency, rate or extent of cell motility. go.json positive regulation of movement of a cell|positive regulation of cell movement|positive regulation of cell locomotion http://purl.obolibrary.org/obo/GO_2000147 GO:0036390 biolink:BiologicalProcess pre-replicative complex assembly involved in bacterial-type DNA replication The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go.json bacterial pre-RC assembly|bacterial pre-replicative complex assembly http://purl.obolibrary.org/obo/GO_0036390 GO:0036391 biolink:CellularComponent medial cortex septin ring A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. go.json http://purl.obolibrary.org/obo/GO_0036391 GO:0036392 biolink:BiologicalProcess chemokine (C-C motif) ligand 20 production The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go.json CCL-20 production|C-C motif chemokine 20 production|CCL20 production http://purl.obolibrary.org/obo/GO_0036392 gocheck_do_not_annotate GO:0036393 biolink:MolecularActivity thiocyanate peroxidase activity Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate. go.json lactoperoxidase activity http://purl.obolibrary.org/obo/GO_0036393 GO:0036394 biolink:BiologicalProcess amylase secretion The controlled release of amylase from a cell. go.json amylase release http://purl.obolibrary.org/obo/GO_0036394 GO:0036395 biolink:BiologicalProcess pancreatic amylase secretion The controlled release of amylase from a cell of the pancreas. go.json http://purl.obolibrary.org/obo/GO_0036395 GO:0036396 biolink:CellularComponent RNA N6-methyladenosine methyltransferase complex A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B). go.json m6A methyltransferase complex|m(6)A writer complex|Mum2, Ime4, and Slz1 complex|WMM complex|METTL3-METTL14-WTAP methyltransferase complex|MIS complex http://purl.obolibrary.org/obo/GO_0036396 GO:0036397 biolink:MolecularActivity formate dehydrogenase (quinone) activity Catalysis of the reaction: formate + a quinone = CO2 + a quinol. EC:1.1.5.6|KEGG_REACTION:R09494|MetaCyc:FORMATEDEHYDROG-RXN go.json Fdh-N activity|formate dehydrogenase-N activity|formate:quinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0036397 GO:0051962 biolink:BiologicalProcess positive regulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. go.json up regulation of nervous system development|stimulation of nervous system development|up-regulation of nervous system development|activation of nervous system development|upregulation of nervous system development http://purl.obolibrary.org/obo/GO_0051962 GO:0051963 biolink:BiologicalProcess regulation of synapse assembly Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. go.json regulation of synapse biogenesis|regulation of synaptogenesis http://purl.obolibrary.org/obo/GO_0051963 goslim_synapse GO:0051960 biolink:BiologicalProcess regulation of nervous system development Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. go.json http://purl.obolibrary.org/obo/GO_0051960 GO:0051961 biolink:BiologicalProcess negative regulation of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. go.json downregulation of nervous system development|down regulation of nervous system development|inhibition of nervous system development|down-regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051961 GO:0051966 biolink:BiologicalProcess regulation of synaptic transmission, glutamatergic Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. go.json http://purl.obolibrary.org/obo/GO_0051966 GO:0051967 biolink:BiologicalProcess negative regulation of synaptic transmission, glutamatergic Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. go.json downregulation of synaptic transmission, glutamatergic|down regulation of synaptic transmission, glutamatergic|inhibition of synaptic transmission, glutamatergic|down-regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051967 GO:0051964 biolink:BiologicalProcess negative regulation of synapse assembly Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. go.json negative regulation of synaptogenesis|downregulation of synapse assembly|down regulation of synapse assembly|inhibition of synapse assembly|down-regulation of synapse assembly|negative regulation of synapse biogenesis http://purl.obolibrary.org/obo/GO_0051964 GO:0051965 biolink:BiologicalProcess positive regulation of synapse assembly Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. go.json stimulation of synapse assembly|up-regulation of synapse assembly|activation of synapse assembly|positive regulation of synapse biogenesis|positive regulation of synaptogenesis|upregulation of synapse assembly|up regulation of synapse assembly http://purl.obolibrary.org/obo/GO_0051965 GO:2000159 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in heart morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000159 GO:0120307 biolink:CellularComponent Hechtian strand An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely. Wikipedia:Hechtian_strand go.json http://purl.obolibrary.org/obo/GO_0120307 GO:0120308 biolink:BiologicalProcess axonemal outer doublet assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule. go.json outer doublet assembly|outer-doublet microtubule assembly|axonemal outer doublet biogenesis|axonemal outer doublet morphogenesis|axonemal outer doublet formation|axoneme outer doublet assembly http://purl.obolibrary.org/obo/GO_0120308 GO:0051968 biolink:BiologicalProcess positive regulation of synaptic transmission, glutamatergic Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. go.json activation of synaptic transmission, glutamatergic|up-regulation of synaptic transmission, glutamatergic|upregulation of synaptic transmission, glutamatergic|up regulation of synaptic transmission, glutamatergic|stimulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051968 GO:0120309 biolink:BiologicalProcess cilium attachment to cell body A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species. go.json flagellar attachment to cell body|ciliary attachment to cell body|flagellum attachment to cell body|cilial attachment to cell body http://purl.obolibrary.org/obo/GO_0120309 GO:0051969 biolink:BiologicalProcess regulation of transmission of nerve impulse Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. go.json regulation of conduction of nerve impulse http://purl.obolibrary.org/obo/GO_0051969 GO:0120303 biolink:BiologicalProcess visually-mediated background adaptation Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells. go.json http://purl.obolibrary.org/obo/GO_0120303 GO:0120304 biolink:BiologicalProcess integument-mediated background adaptation Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument. go.json http://purl.obolibrary.org/obo/GO_0120304 GO:0120305 biolink:BiologicalProcess regulation of pigmentation Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism. go.json http://purl.obolibrary.org/obo/GO_0120305 GO:0120306 biolink:BiologicalProcess cellular response to actin cytoskeletal stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton. go.json cellular response to actin cytoskeleton stress|response to latrunculin B|response to latrunculin A|cellular response to latrunculin B|cellular response to latrunculin A http://purl.obolibrary.org/obo/GO_0120306 GO:0036387 biolink:CellularComponent pre-replicative complex A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go.json pre-RC|pre-replication complex http://purl.obolibrary.org/obo/GO_0036387 GO:2000151 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000151 GO:0120300 biolink:MolecularActivity peptide lactyltransferase activity Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein]. RHEA:61997 go.json http://purl.obolibrary.org/obo/GO_0120300 GO:0036388 biolink:BiologicalProcess pre-replicative complex assembly The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go.json pre-replication complex assembly|pre-RC assembly http://purl.obolibrary.org/obo/GO_0036388 GO:2000152 biolink:BiologicalProcess regulation of ubiquitin-specific protease activity Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity. go.json regulation of UBP|regulation of UCH2|regulation of deubiquitinase activity http://purl.obolibrary.org/obo/GO_2000152 GO:0036389 biolink:CellularComponent bacterial pre-replicative complex A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go.json bacterial pre-RC http://purl.obolibrary.org/obo/GO_0036389 GO:2000153 biolink:BiologicalProcess obsolete regulation of flagellar cell motility OBSOLETE. Any process that modulates the frequency, rate or extent of flagellar cell motility. go.json regulation of flagellar cell motility http://purl.obolibrary.org/obo/GO_2000153 GO:0120301 biolink:MolecularActivity histone lactyltransferase activity Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[histone]. go.json http://purl.obolibrary.org/obo/GO_0120301 GO:2000154 biolink:BiologicalProcess obsolete negative regulation of flagellar cell motility OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of flagellar cell motility. go.json negative regulation of flagellar cell motility http://purl.obolibrary.org/obo/GO_2000154 GO:0120302 biolink:BiologicalProcess background adaptation Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity. go.json http://purl.obolibrary.org/obo/GO_0120302 GO:2000155 biolink:BiologicalProcess positive regulation of cilium-dependent cell motility Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. go.json positive regulation of ciliary cell motility http://purl.obolibrary.org/obo/GO_2000155 GO:2000156 biolink:BiologicalProcess regulation of retrograde vesicle-mediated transport, Golgi to ER Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER. go.json regulation of cis-Golgi to rough ER vesicle-mediated transport|regulation of retrograde transport, Golgi to ER|regulation of cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|regulation of retrograde (Golgi to ER) transport|regulation of retrograde transport, Golgi to endoplasmic reticulum|regulation of cis-Golgi to rough endoplasmic reticulum transport|regulation of cis-Golgi to rough ER transport|regulation of retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum http://purl.obolibrary.org/obo/GO_2000156 GO:2000157 biolink:BiologicalProcess negative regulation of ubiquitin-specific protease activity Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. go.json negative regulation of UCH2|negative regulation of UBP|negative regulation of deubiquitinase activity|negative regulation of ubiquitin hydrolase activity http://purl.obolibrary.org/obo/GO_2000157 GO:2000158 biolink:BiologicalProcess positive regulation of ubiquitin-specific protease activity Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. go.json positive regulation of UBP|positive regulation of ubiquitin hydrolase activity|positive regulation of deubiquitinase activity|positive regulation of UCH2 http://purl.obolibrary.org/obo/GO_2000158 GO:0036380 biolink:MolecularActivity UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. KEGG_REACTION:R08856|RHEA:28090|MetaCyc:GLCNACPTRANS-RXN|EC:2.7.8.33 go.json UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|GlcNAc-P-P-Und synthase activity|UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-glucosaminephosphotransferase activity|UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase activity http://purl.obolibrary.org/obo/GO_0036380 GO:0036381 biolink:MolecularActivity pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate. KEGG_REACTION:R10089|MetaCyc:RXN-11322|EC:4.3.3.6|RHEA:31507 go.json PdxST activity|pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) activity http://purl.obolibrary.org/obo/GO_0036381 GO:0036382 biolink:MolecularActivity flavin reductase (NADH) activity Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+. MetaCyc:1.5.1.36-RXN|KEGG_REACTION:R09662|EC:1.5.1.36|RHEA:31303 go.json flavin:NADH oxidoreductase activity|NADH-dependent flavin reductase activity http://purl.obolibrary.org/obo/GO_0036382 GO:0036383 biolink:MolecularActivity 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O. MetaCyc:1.14.14.12-RXN|EC:1.14.14.12|KEGG_REACTION:R09819|RHEA:31731 go.json http://purl.obolibrary.org/obo/GO_0036383 GO:0036384 biolink:MolecularActivity cytidine-diphosphatase activity Catalysis of the reaction: CDP + H2O = CMP + phosphate. RHEA:64880 go.json CDPase activity http://purl.obolibrary.org/obo/GO_0036384 GO:0036385 biolink:BiologicalProcess nucleoid DNA packaging Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid. go.json http://purl.obolibrary.org/obo/GO_0036385 GO:2000150 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000150 GO:0036386 biolink:BiologicalProcess bacterial nucleoid DNA packaging Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling. go.json prokaryotic DNA condensation|nucleoid compaction|chromosomal compaction http://purl.obolibrary.org/obo/GO_0036386 GO:0051973 biolink:BiologicalProcess positive regulation of telomerase activity Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). go.json telomerase activator|up-regulation of telomerase activity|up regulation of telomerase activity|activation of telomerase activity|stimulation of telomerase activity|upregulation of telomerase activity http://purl.obolibrary.org/obo/GO_0051973 GO:0051974 biolink:BiologicalProcess negative regulation of telomerase activity Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). go.json telomerase inhibitor|down regulation of telomerase activity|inhibition of telomerase activity|downregulation of telomerase activity|down-regulation of telomerase activity http://purl.obolibrary.org/obo/GO_0051974 GO:0051971 biolink:BiologicalProcess positive regulation of transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. go.json up-regulation of transmission of nerve impulse|positive regulation of conduction of nerve impulse|up regulation of transmission of nerve impulse|activation of transmission of nerve impulse|stimulation of transmission of nerve impulse|upregulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051971 GO:0051972 biolink:BiologicalProcess regulation of telomerase activity Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. go.json telomerase regulator http://purl.obolibrary.org/obo/GO_0051972 GO:0051977 biolink:BiologicalProcess lysophospholipid transport The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. go.json http://purl.obolibrary.org/obo/GO_0051977 GO:0051978 biolink:MolecularActivity lysophospholipid:sodium symporter activity Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. go.json lysophospholipid transporter activity http://purl.obolibrary.org/obo/GO_0051978 GO:0051975 biolink:BiologicalProcess lysine biosynthetic process via alpha-aminoadipate and saccharopine The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine. MetaCyc:LYSINE-AMINOAD-PWY go.json lysine biosynthetic process via aminoadipic acid and saccharopine|lysine biosynthesis via aminoadipic acid and saccharopine http://purl.obolibrary.org/obo/GO_0051975 GO:0051976 biolink:BiologicalProcess lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine. MetaCyc:PWY-3081 go.json lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate|lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate http://purl.obolibrary.org/obo/GO_0051976 GO:0051979 biolink:BiologicalProcess alginic acid acetylation The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate. go.json alginate acetylation http://purl.obolibrary.org/obo/GO_0051979 GO:0120314 biolink:BiologicalProcess negative regulation of oocyte karyosome formation Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. go.json http://purl.obolibrary.org/obo/GO_0120314 GO:0120315 biolink:BiologicalProcess positive regulation of oocyte karyosome formation Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. go.json http://purl.obolibrary.org/obo/GO_0120315 GO:0120316 biolink:BiologicalProcess sperm flagellum assembly The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium). go.json http://purl.obolibrary.org/obo/GO_0120316 GO:0120317 biolink:BiologicalProcess sperm mitochondrial sheath assembly The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum. go.json http://purl.obolibrary.org/obo/GO_0120317 GO:0036376 biolink:BiologicalProcess sodium ion export across plasma membrane The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. go.json sodium export|sodium ion export|sodium ion export from cell http://purl.obolibrary.org/obo/GO_0036376 GO:2000162 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000162 GO:0120310 biolink:BiologicalProcess amastigogenesis The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites. go.json http://purl.obolibrary.org/obo/GO_0120310 GO:0036377 biolink:BiologicalProcess arbuscular mycorrhizal association A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil. go.json arbuscular mycorrhizas formation|arbuscular mycorrhizal symbiosis|arbuscular mycorrhizae formation http://purl.obolibrary.org/obo/GO_0036377 GO:2000163 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in outflow tract morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000163 GO:0061300 biolink:BiologicalProcess cerebellum vasculature development The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061300 GO:0120311 biolink:BiologicalProcess ciliary pro-basal body maturation A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium. go.json flagellar pro-basal body maturation|flagellar probasal body maturation|pro-basal body maturation http://purl.obolibrary.org/obo/GO_0120311 GO:0061301 biolink:BiologicalProcess cerebellum vasculature morphogenesis The process in which the vasculature of the cerebellum is generated and organized. go.json http://purl.obolibrary.org/obo/GO_0061301 GO:0036378 biolink:BiologicalProcess calcitriol biosynthetic process from calciol Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol. go.json calcitriol biosynthesis from calciol|vitamin D3 activation|1alpha,25(OH)2D3 biosynthesis|1alpha,25-dihydroxyvitamin D3 biosynthesis|1alpha,25-dihydroxycholecalciferol biosynthesis http://purl.obolibrary.org/obo/GO_0036378 GO:0120312 biolink:BiologicalProcess ciliary basal body segregation The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites. go.json microtubule basal body separation|microtubule basal body segregation|ciliary basal body separation http://purl.obolibrary.org/obo/GO_0120312 GO:2000164 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000164 GO:0120313 biolink:BiologicalProcess regulation of oocyte karyosome formation Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. go.json http://purl.obolibrary.org/obo/GO_0120313 GO:0061302 biolink:BiologicalProcess smooth muscle cell-matrix adhesion The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules. go.json http://purl.obolibrary.org/obo/GO_0061302 GO:2000165 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in pericardium morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000165 GO:0036379 biolink:CellularComponent myofilament Any of the smallest contractile units of a myofibril (striated muscle fiber). go.json striated muscle filament http://purl.obolibrary.org/obo/GO_0036379 GO:2000166 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in pericardium morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000166 GO:0061303 biolink:BiologicalProcess cornea development in camera-type eye The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. go.json http://purl.obolibrary.org/obo/GO_0061303 GO:2000167 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in neural tube closure Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. go.json http://purl.obolibrary.org/obo/GO_2000167 GO:0061304 biolink:BiologicalProcess retinal blood vessel morphogenesis The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. go.json http://purl.obolibrary.org/obo/GO_0061304 GO:0061305 biolink:BiologicalProcess maintenance of bipolar cell polarity regulating cell shape The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell. go.json http://purl.obolibrary.org/obo/GO_0061305 GO:2000168 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in neural tube closure Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. go.json http://purl.obolibrary.org/obo/GO_2000168 GO:0061306 biolink:BiologicalProcess obsolete DNA strand renaturation involved in double-strand break repair OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair. go.json http://purl.obolibrary.org/obo/GO_0061306 GO:2000169 biolink:BiologicalProcess regulation of peptidyl-cysteine S-nitrosylation Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. go.json http://purl.obolibrary.org/obo/GO_2000169 GO:0061307 biolink:BiologicalProcess cardiac neural crest cell differentiation involved in heart development The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. go.json http://purl.obolibrary.org/obo/GO_0061307 GO:0061308 biolink:BiologicalProcess cardiac neural crest cell development involved in heart development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. go.json http://purl.obolibrary.org/obo/GO_0061308 GO:0061309 biolink:BiologicalProcess cardiac neural crest cell development involved in outflow tract morphogenesis The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. go.json http://purl.obolibrary.org/obo/GO_0061309 GO:0036370 biolink:MolecularActivity D-alanyl carrier activity Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG). go.json D-alanyl carrier protein http://purl.obolibrary.org/obo/GO_0036370 GO:0036371 biolink:BiologicalProcess protein localization to T-tubule A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. go.json protein localization to transverse tubule|protein localization to T tubule|protein localisation to T-tubule http://purl.obolibrary.org/obo/GO_0036371 GO:0036372 biolink:BiologicalProcess opsin transport The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. go.json ciliary transport of opsin http://purl.obolibrary.org/obo/GO_0036372 GO:0051970 biolink:BiologicalProcess negative regulation of transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. go.json downregulation of transmission of nerve impulse|inhibition of transmission of nerve impulse|negative regulation of conduction of nerve impulse|down-regulation of transmission of nerve impulse|down regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051970 GO:0036373 biolink:MolecularActivity L-fucose mutarotase activity Catalysis of the reaction: alpha-L-fucose = beta-L-fucose. MetaCyc:RXN0-5298|EC:5.1.3.29|RHEA:25580 go.json fucose 1-epimerase activity|alpha-L-fucose 1-epimerase activity|type-2 mutarotase activity http://purl.obolibrary.org/obo/GO_0036373 GO:0036374 biolink:MolecularActivity glutathione hydrolase activity Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate. Reactome:R-HSA-9026927|Reactome:R-HSA-9026916|Reactome:R-HSA-5433072|Reactome:R-HSA-5602984|Reactome:R-HSA-9026912|Reactome:R-HSA-9026757|KEGG_REACTION:R00494|EC:3.4.19.13|Reactome:R-HSA-9035966|Reactome:R-HSA-8943279|MetaCyc:RXN-12618|Reactome:R-HSA-266046|Reactome:R-HSA-9026907|RHEA:28807|Reactome:R-HSA-1222712 go.json glutathionase activity|gamma-glutamyltranspeptidase activity http://purl.obolibrary.org/obo/GO_0036374 GO:2000160 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in heart morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000160 GO:2000161 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis. go.json http://purl.obolibrary.org/obo/GO_2000161 GO:0036375 biolink:CellularComponent Kibra-Ex-Mer complex An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2. go.json KEM complex|Kbr, Ex and Mer complex http://purl.obolibrary.org/obo/GO_0036375 GO:0051984 biolink:BiologicalProcess positive regulation of chromosome segregation Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. go.json upregulation of chromosome segregation|up regulation of chromosome segregation|stimulation of chromosome segregation|up-regulation of chromosome segregation|activation of chromosome segregation http://purl.obolibrary.org/obo/GO_0051984 GO:0051985 biolink:BiologicalProcess negative regulation of chromosome segregation Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. go.json down regulation of chromosome segregation|inhibition of chromosome segregation|down-regulation of chromosome segregation|downregulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0051985 GO:0051982 biolink:MolecularActivity copper-nicotianamine transmembrane transporter activity Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other. go.json Cu-NA chelate transporter activity http://purl.obolibrary.org/obo/GO_0051982 GO:0051983 biolink:BiologicalProcess regulation of chromosome segregation Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. go.json http://purl.obolibrary.org/obo/GO_0051983 GO:0051988 biolink:BiologicalProcess regulation of attachment of spindle microtubules to kinetochore Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. go.json regulation of kinetochore-microtubule attachment http://purl.obolibrary.org/obo/GO_0051988 GO:0051989 biolink:MolecularActivity coproporphyrinogen dehydrogenase activity Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine. RHEA:15425|MetaCyc:HEMN-RXN|EC:1.3.98.3 go.json radical SAM enzyme activity|oxygen-independent coproporphyrinogen-III oxidase activity|coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)|HemN|coproporphyrinogen III oxidase activity http://purl.obolibrary.org/obo/GO_0051989 GO:0051986 biolink:BiologicalProcess negative regulation of attachment of spindle microtubules to kinetochore Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. go.json downregulation of attachment of spindle microtubules to kinetochore|inhibition of attachment of spindle microtubules to kinetochore|down-regulation of attachment of spindle microtubules to kinetochore|down regulation of attachment of spindle microtubules to kinetochore http://purl.obolibrary.org/obo/GO_0051986 GO:0051987 biolink:BiologicalProcess positive regulation of attachment of spindle microtubules to kinetochore Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. go.json up-regulation of attachment of spindle microtubules to kinetochore|up regulation of attachment of spindle microtubules to kinetochore|activation of attachment of spindle microtubules to kinetochore|stimulation of attachment of spindle microtubules to kinetochore|upregulation of attachment of spindle microtubules to kinetochore http://purl.obolibrary.org/obo/GO_0051987 GO:0036365 biolink:BiologicalProcess transforming growth factor beta2 activation The release of transforming growth factor beta 2 (TGF-beta2) from its latent state. go.json TGFB2 activation|TGFbeta 2 activation|TGF-beta 2 activation http://purl.obolibrary.org/obo/GO_0036365 GO:2000173 biolink:BiologicalProcess negative regulation of branching morphogenesis of a nerve Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. go.json http://purl.obolibrary.org/obo/GO_2000173 GO:2000174 biolink:BiologicalProcess regulation of pro-T cell differentiation Any process that modulates the frequency, rate or extent of pro-T cell differentiation. go.json regulation of pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000174 GO:0036366 biolink:BiologicalProcess transforming growth factor beta3 activation The release of transforming growth factor beta 3 (TGF-beta3) from its latent state. go.json TGFB3 activation|TGFbeta 3 activation|TGF-beta 3 activation http://purl.obolibrary.org/obo/GO_0036366 GO:0036367 biolink:BiologicalProcess light adaption The ability of a photoreceptor to adjust to varying levels of light. go.json http://purl.obolibrary.org/obo/GO_0036367 GO:2000175 biolink:BiologicalProcess negative regulation of pro-T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation. go.json negative regulation of pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000175 GO:0036368 biolink:BiologicalProcess cone photoresponse recovery The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers. go.json cone phototransduction termination|cone response recovery http://purl.obolibrary.org/obo/GO_0036368 GO:2000176 biolink:BiologicalProcess positive regulation of pro-T cell differentiation Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation. go.json positive regulation of pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000176 GO:0036369 biolink:BiologicalProcess transcription factor catabolic process The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. go.json proteasome-mediated transcription factor catabolism|transcription factor degradation|transcription factor catabolism|sequence-specific DNA binding transcription factor catabolic process|transcription factor breakdown http://purl.obolibrary.org/obo/GO_0036369 GO:2000177 biolink:BiologicalProcess regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. go.json http://purl.obolibrary.org/obo/GO_2000177 GO:2000178 biolink:BiologicalProcess negative regulation of neural precursor cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. go.json http://purl.obolibrary.org/obo/GO_2000178 GO:2000179 biolink:BiologicalProcess positive regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. go.json http://purl.obolibrary.org/obo/GO_2000179 GO:0036360 biolink:BiologicalProcess sorocarp stalk morphogenesis The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum. go.json fruiting body stalk morphogenesis http://purl.obolibrary.org/obo/GO_0036360 GO:0036361 biolink:MolecularActivity racemase activity, acting on amino acids and derivatives Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative. go.json http://purl.obolibrary.org/obo/GO_0036361 GO:0051980 biolink:MolecularActivity iron-nicotianamine transmembrane transporter activity Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other. go.json Fe-NA chelate transporter activity http://purl.obolibrary.org/obo/GO_0051980 GO:2000170 biolink:BiologicalProcess positive regulation of peptidyl-cysteine S-nitrosylation Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. go.json http://purl.obolibrary.org/obo/GO_2000170 GO:0036362 biolink:CellularComponent ascus membrane A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi. go.json http://purl.obolibrary.org/obo/GO_0036362 GO:0051981 biolink:MolecularActivity copper chelate transmembrane transporter activity Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions. go.json http://purl.obolibrary.org/obo/GO_0051981 GO:0036363 biolink:BiologicalProcess transforming growth factor beta activation The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms. go.json L-TGF-beta activation|TGFbeta activation|TGFB activation|latent TGF-beta activation|TGF-B activation|TGF-beta activation http://purl.obolibrary.org/obo/GO_0036363 GO:2000171 biolink:BiologicalProcess negative regulation of dendrite development Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. go.json http://purl.obolibrary.org/obo/GO_2000171 GO:0036364 biolink:BiologicalProcess transforming growth factor beta1 activation The release of transforming growth factor beta1 (TGF-beta1) from its latent state. go.json TGFB1 activation|L-TGF-beta 1 activation|TGFbeta 1 activation|latent-TGF-beta1 activation|transforming growth factor-beta1 activation|TGF-beta 1 activation http://purl.obolibrary.org/obo/GO_0036364 GO:2000172 biolink:BiologicalProcess regulation of branching morphogenesis of a nerve Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. go.json http://purl.obolibrary.org/obo/GO_2000172 GO:0120178 biolink:BiologicalProcess steroid hormone biosynthetic process The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. go.json http://purl.obolibrary.org/obo/GO_0120178 GO:0120179 biolink:BiologicalProcess adherens junction disassembly The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go.json http://purl.obolibrary.org/obo/GO_0120179 GO:0120174 biolink:BiologicalProcess stress-induced homeostatically regulated protein degradation pathway A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway. go.json SHRED pathway http://purl.obolibrary.org/obo/GO_0120174 GO:0120175 biolink:BiologicalProcess regulation of torso signaling pathway Any process that modulates the frequency, rate or extent of the torso signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120175 GO:0120176 biolink:BiologicalProcess positive regulation of torso signaling pathway Any process that activates or increases the frequency, rate or extent of the torso signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120176 GO:0120177 biolink:BiologicalProcess negative regulation of torso signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120177 GO:0120170 biolink:MolecularActivity intraciliary transport particle B binding Interacting selectively and non-covalently with an intraciliary transport particle B (IFT B) complex. go.json intraflagellar transport complex B binding|IFT B complex binding|intraflagellar transport particle B binding|intraciliary transport complex B binding http://purl.obolibrary.org/obo/GO_0120170 GO:0120171 biolink:CellularComponent Cdc24p-Far1p-Gbetagamma complex A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit). go.json Cdc24p-Far1p-BG complex|CDC24-FAR1-Gbetagamma complex|CDC24-FAR1-BG complex http://purl.obolibrary.org/obo/GO_0120171 GO:0120172 biolink:BiologicalProcess positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly Any process that activates or increases the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly. go.json http://purl.obolibrary.org/obo/GO_0120172 GO:0120173 biolink:BiologicalProcess regulation of actin filament bundle convergence involved in mitotic contractile ring assembly Any process that modulates the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly. go.json http://purl.obolibrary.org/obo/GO_0120173 GO:0120189 biolink:BiologicalProcess positive regulation of bile acid secretion Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. go.json http://purl.obolibrary.org/obo/GO_0120189 GO:0120185 biolink:BiologicalProcess MBF transcription complex assembly The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex. go.json DSC1 transcription factor complex assembly|Mlu1-box binding factor assembly|MBF complex assembly http://purl.obolibrary.org/obo/GO_0120185 GO:0120186 biolink:BiologicalProcess negative regulation of protein localization to chromatin Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin. go.json negative regulation of protein localisation to chromatin http://purl.obolibrary.org/obo/GO_0120186 GO:0120187 biolink:BiologicalProcess positive regulation of protein localization to chromatin Any process that activates or increases the frequency, rate or extent of protein localization to chromatin. go.json positive regulation of protein localisation to chromatin http://purl.obolibrary.org/obo/GO_0120187 GO:0120188 biolink:BiologicalProcess regulation of bile acid secretion Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. go.json http://purl.obolibrary.org/obo/GO_0120188 GO:0120181 biolink:BiologicalProcess focal adhesion disassembly The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity. go.json http://purl.obolibrary.org/obo/GO_0120181 GO:0120182 biolink:BiologicalProcess regulation of focal adhesion disassembly Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components. go.json http://purl.obolibrary.org/obo/GO_0120182 GO:0120183 biolink:BiologicalProcess positive regulation of focal adhesion disassembly Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components. go.json http://purl.obolibrary.org/obo/GO_0120183 GO:0120184 biolink:BiologicalProcess negative regulation of focal adhesion disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components. go.json http://purl.obolibrary.org/obo/GO_0120184 GO:0120180 biolink:BiologicalProcess cell-substrate junction disassembly The disaggregation of a cell-substrate junction into its constituent components. go.json http://purl.obolibrary.org/obo/GO_0120180 GO:0120196 biolink:BiologicalProcess negative regulation of anther dehiscence Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence. go.json http://purl.obolibrary.org/obo/GO_0120196 GO:0120197 biolink:BiologicalProcess mucociliary clearance The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways. go.json mucociliary transport|MCT|MCC http://purl.obolibrary.org/obo/GO_0120197 GO:0120198 biolink:BiologicalProcess positive regulation of imaginal disc-derived wing size Any process that increases the size of an imaginal disc-derived wing. go.json http://purl.obolibrary.org/obo/GO_0120198 GO:0120199 biolink:CellularComponent cone photoreceptor outer segment The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins. go.json http://purl.obolibrary.org/obo/GO_0120199 GO:0120192 biolink:BiologicalProcess tight junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. go.json occluding junction assembly|occluding cell junction assembly http://purl.obolibrary.org/obo/GO_0120192 GO:0120193 biolink:BiologicalProcess tight junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. go.json occluding junction organization|occluding cell junction organization http://purl.obolibrary.org/obo/GO_0120193 GO:0120194 biolink:BiologicalProcess regulation of anther dehiscence Any process involved in the dehiscence of an anther to release the pollen grains contained within it. go.json http://purl.obolibrary.org/obo/GO_0120194 GO:0120195 biolink:BiologicalProcess positive regulation of anther dehiscence Any process that activates or increases the frequency, rate or extent of anther dehiscence. go.json http://purl.obolibrary.org/obo/GO_0120195 GO:0120190 biolink:BiologicalProcess negative regulation of bile acid secretion Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. go.json http://purl.obolibrary.org/obo/GO_0120190 GO:0120191 biolink:BiologicalProcess negative regulation of termination of RNA polymerase II transcription Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription. go.json downregulation of RNA polymerase II transcription termination factor activity|repression of termination of RNA polymerase II transcription|down-regulation of RNA 3'-end formation by RNA polymerase II|negative regulation of RNA 3'-end formation by RNA polymerase II|repression of RNA polymerase II transcription termination|repression of transcription termination from Pol II promoter|downregulation of termination of RNA polymerase II transcription|downregulation of transcription termination from RNA polymerase II promoter|downregulation of transcription termination from Pol II promoter|down regulation of RNA 3'-end formation by RNA polymerase II|down-regulation of RNA polymerase II transcription termination|negative regulation of RNA polymerase II transcription termination|down regulation of termination of RNA polymerase II transcription|down regulation of RNA polymerase II transcription termination|down regulation of transcription termination from Pol II promoter|downregulation of RNA 3'-end formation by RNA polymerase II|down-regulation of termination of RNA polymerase II transcription|negative regulation of RNA polymerase II transcription termination factor activity|repression of transcription termination from RNA polymerase II promoter|down-regulation of RNA polymerase II transcription termination factor activity|downregulation of RNA polymerase II transcription termination|negative regulation of transcription termination from Pol II promoter|down-regulation of transcription termination from Pol II promoter|negative regulation of transcription termination from RNA polymerase II promoter|down regulation of RNA polymerase II transcription termination factor activity|repression of RNA polymerase II transcription termination factor activity|down-regulation of transcription termination from RNA polymerase II promoter|repression of RNA 3'-end formation by RNA polymerase II|down regulation of transcription termination from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0120191 GO:0120138 biolink:BiologicalProcess regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. go.json http://purl.obolibrary.org/obo/GO_0120138 GO:0120139 biolink:BiologicalProcess positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. go.json http://purl.obolibrary.org/obo/GO_0120139 GO:0120134 biolink:CellularComponent proximal portion of axoneme The portion of the axoneme that is close to the base of the cilium. go.json proximal part of axoneme http://purl.obolibrary.org/obo/GO_0120134 GO:0120135 biolink:CellularComponent distal portion of axoneme The portion of the axoneme that is close to the tip of the cilium. go.json distal part of axoneme http://purl.obolibrary.org/obo/GO_0120135 GO:0120136 biolink:MolecularActivity dUMP kinase activity Catalysis of the reaction: ATP + dUMP = ADP + dUDP. RHEA:30655 go.json ATP:dUMP phosphotransferase activity|dUMP-kinase activity|deoxyuridine monophosphate kinase activity http://purl.obolibrary.org/obo/GO_0120136 GO:0120137 biolink:BiologicalProcess positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. go.json http://purl.obolibrary.org/obo/GO_0120137 GO:0120132 biolink:BiologicalProcess positive regulation of apoptotic process in bone marrow cell Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow. go.json positive regulation of bone marrow cell programmed cell death by apoptosis|positive regulation of bone marrow cell apoptosis|positive regulation of killing of bone marrow cells|up regulation of apoptosis in bone marrow|positive regulation of programmed cell death, bone marrow cells|activation of apoptosis in bone marrow|positive regulation of apoptotic process in bone marrow|up-regulation of apoptosis in bone marrow|positive regulation of apoptosis in bone marrow|positive regulation of programmed cell death of bone marrow cells by apoptosis|upregulation of apoptosis in bone marrow http://purl.obolibrary.org/obo/GO_0120132 GO:0120133 biolink:BiologicalProcess negative regulation of actin cortical patch assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches. go.json downregulation of actin cortical patch assembly|inhibition of actin cortical patch assembly|down-regulation of actin cortical patch assembly|down regulation of actin cortical patch assembly http://purl.obolibrary.org/obo/GO_0120133 GO:0120149 biolink:CellularComponent host cell peroxisome A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. go.json host peroxisome http://purl.obolibrary.org/obo/GO_0120149 GO:0120145 biolink:BiologicalProcess protein localization to basal ectoplasmic specialization A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization. go.json protein localisation in basal ectoplasmic specialization|protein localisation to basal ectoplasmic specialization|protein localization in basal ectoplasmic specialization http://purl.obolibrary.org/obo/GO_0120145 GO:0120146 biolink:MolecularActivity sulfatide binding Interacting selectively and non-covalently with sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group. go.json sulfated galactocerebroside binding|3-O-sulfogalactosylceramide binding|SM4 binding http://purl.obolibrary.org/obo/GO_0120146 GO:0120147 biolink:MolecularActivity Formylglycine-generating oxidase activity Catalysis of the reaction: A [sulfatase]-L-cysteine + O(2) + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H(2)O. RHEA:51152|MetaCyc:RXN-16226|EC:1.8.3.7 go.json http://purl.obolibrary.org/obo/GO_0120147 GO:0120148 biolink:CellularComponent host cell centrosome A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. go.json host centrosome http://purl.obolibrary.org/obo/GO_0120148 GO:0120141 biolink:BiologicalProcess regulation of ecdysone receptor-mediated signaling pathway Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120141 GO:0120142 biolink:BiologicalProcess positive regulation of ecdysone receptor-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120142 GO:0120143 biolink:BiologicalProcess negative regulation of ecdysone receptor-mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120143 GO:0120140 biolink:BiologicalProcess negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. go.json http://purl.obolibrary.org/obo/GO_0120140 GO:0120157 biolink:CellularComponent PAR polarity complex A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. go.json Cdc42p GEF-PAK complex|PAR6-PAR3-aPKC complex|BEM1-CDC24-CLA4 complex|apical polarity complex|PAR3-PAR6-atypical PKC|PAR3/PAR6/aPKC http://purl.obolibrary.org/obo/GO_0120157 GO:0120158 biolink:BiologicalProcess positive regulation of collagen catabolic process Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. go.json up regulation of collagen catabolic process|up-regulation of collagen catabolic process|activation of collagen catabolic process|positive regulation of collagen degradation|positive regulation of collagen catabolism|upregulation of collagen catabolic process|positive regulation of collagen breakdown http://purl.obolibrary.org/obo/GO_0120158 GO:0120159 biolink:MolecularActivity rRNA pseudouridine synthase activity Catalysis of the reaction: an rRNA uridine = an rRNA pseudouridine. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. EC:5.4.99.19|EC:5.4.99.29|EC:5.4.99.24|EC:5.4.99.23|EC:5.4.99.22|EC:5.4.99.43|EC:5.4.99.21|EC:5.4.99.20 go.json 23S rRNA pseudouridine(2605) synthase|23S rRNA pseudouridine(1911/1915/1917) synthase|23S rRNA pseudouridine(2604) synthase|23S rRNA pseudouridine(746) synthase|23S rRNA pseudouridine(2457) synthase|21S rRNA pseudouridine(2819) synthase|23S rRNA pseudouridine(955/2504/2580) synthase|16S rRNA pseudouridine(516) synthase http://purl.obolibrary.org/obo/GO_0120159 GO:0120152 biolink:MolecularActivity calcium-dependent outer dynein arm binding Interacting selectively and non-covalently with an outer dynein arm in the presence of calcium. go.json http://purl.obolibrary.org/obo/GO_0120152 GO:0120153 biolink:MolecularActivity calcium-dependent carbohydrate binding Interacting selectively and non-covalently with any carbohydrate in the presence of calcium. go.json http://purl.obolibrary.org/obo/GO_0120153 GO:0120154 biolink:BiologicalProcess negative regulation of ERBB4 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway. go.json http://purl.obolibrary.org/obo/GO_0120154 GO:0120155 biolink:CellularComponent MIH complex A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins. go.json Mlc1p-Iqg1p-Hof1p complex http://purl.obolibrary.org/obo/GO_0120155 GO:0120150 biolink:BiologicalProcess regulation of mitotic actomyosin contractile ring disassembly Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly. go.json regulation of mitotic constriction ring disassembly|regulation of mitotic cytokinetic ring disassembly|regulation of mitotic actomyosin ring disassembly|regulation of mitotic contractile actomyosin ring disassembly|regulation of mitotic CAR disassembly http://purl.obolibrary.org/obo/GO_0120150 GO:0120151 biolink:BiologicalProcess positive regulation of mitotic actomyosin contractile ring disassembly Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly. go.json positive regulation of mitotic CAR disassembly|positive regulation of mitotic constriction ring disassembly|positive regulation of mitotic actomyosin ring disassembly|positive regulation of mitotic cytokinetic ring disassembly|positive regulation of mitotic contractile actomyosin ring disassembly http://purl.obolibrary.org/obo/GO_0120151 GO:0120168 biolink:BiologicalProcess detection of hot stimulus involved in thermoception The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception. go.json thermoception, sensory transduction of hot stimulus|thermoception, sensory detection of hot stimulus|sensory detection of hot stimulus during thermoception|sensory detection of heat stimulus during thermoception|thermoception, sensory detection of heat stimulus|thermoception, sensory transduction of heat stimulus|sensory transduction of heat stimulus during thermoception|sensory transduction of hot stimulus during thermoception http://purl.obolibrary.org/obo/GO_0120168 GO:0120169 biolink:BiologicalProcess detection of cold stimulus involved in thermoception The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception. go.json sensory detection of cold stimulus during thermoception|sensory transduction of cold stimulus during thermoception|thermoception, sensory detection of cold stimulus|thermoception, sensory transduction of cold stimulus http://purl.obolibrary.org/obo/GO_0120169 GO:0120163 biolink:BiologicalProcess negative regulation of cold-induced thermogenesis Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis. go.json negative regulation of CIT http://purl.obolibrary.org/obo/GO_0120163 GO:0120164 biolink:BiologicalProcess conidium germination The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination. go.json http://purl.obolibrary.org/obo/GO_0120164 GO:0120165 biolink:BiologicalProcess perithecium development The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck. go.json http://purl.obolibrary.org/obo/GO_0120165 GO:0120166 biolink:BiologicalProcess protoperithecium formation The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium. go.json http://purl.obolibrary.org/obo/GO_0120166 GO:0120160 biolink:MolecularActivity intraciliary transport particle A binding Interacting selectively and non-covalently with an intraciliary transport particle A (IFT A) complex. go.json intraciliary transport complex A binding|intraflagellar transport complex A binding|IFT A complex binding|intraflagellar transport particle A binding http://purl.obolibrary.org/obo/GO_0120160 GO:0120161 biolink:BiologicalProcess regulation of cold-induced thermogenesis Any process that modulates the frequency, rate or extent of cold-induced thermogenesis. go.json regulation of CIT http://purl.obolibrary.org/obo/GO_0120161 GO:0120162 biolink:BiologicalProcess positive regulation of cold-induced thermogenesis Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis. go.json positive regulation of CIT http://purl.obolibrary.org/obo/GO_0120162 GO:0036516 biolink:BiologicalProcess chemoattraction of dopaminergic neuron axon The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. go.json chemoattraction of DA axon|chemoattraction of dopaminergic axon http://purl.obolibrary.org/obo/GO_0036516 GO:0036517 biolink:BiologicalProcess chemoattraction of serotonergic neuron axon The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. go.json chemoattraction of serotonergic axon|chemoattraction of 5-HT axon http://purl.obolibrary.org/obo/GO_0036517 GO:1901048 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription, that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. go.json TGF-beta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of multicellular organism growth|TGFbeta receptor signaling pathway of regulation of body size|transforming growth factor beta receptor signalling pathway of regulation of body size|transforming growth factor beta receptor signaling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of body size|TGF-beta receptor signaling pathway of regulation of body growth|TGF-beta receptor signalling pathway of regulation of body growth|TGFbeta receptor signaling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signalling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signaling pathway of regulation of multicellular organism growth|TGF-beta receptor signalling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of body growth|transforming growth factor beta receptor signalling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of body growth|TGFbeta receptor signalling pathway of regulation of body growth http://purl.obolibrary.org/obo/GO_1901048 GO:0036518 biolink:BiologicalProcess chemorepulsion of dopaminergic neuron axon The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. go.json chemorepulsion of DA axon|chemorepulsion of dopaminergic axon http://purl.obolibrary.org/obo/GO_0036518 GO:1901049 biolink:BiologicalProcess atropine metabolic process The chemical reactions and pathways involving atropine. go.json atropine metabolism http://purl.obolibrary.org/obo/GO_1901049 GO:0036519 biolink:BiologicalProcess chemorepulsion of serotonergic neuron axon The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. go.json chemorepulsion of serotonergic axon|chemorepulsion of 5-HT axon http://purl.obolibrary.org/obo/GO_0036519 GO:1901046 biolink:BiologicalProcess positive regulation of oviposition Any process that activates or increases the frequency, rate or extent of oviposition. go.json positive regulation of egg laying|up regulation of egg laying|up-regulation of oviposition|positive regulation of egg-laying|up regulation of egg-laying|up-regulation of egg laying|up regulation of oviposition|activation of oviposition|up-regulation of egg-laying|activation of egg laying|upregulation of oviposition|upregulation of egg laying|activation of egg-laying|upregulation of egg-laying http://purl.obolibrary.org/obo/GO_1901046 GO:1901047 biolink:BiologicalProcess insulin receptor signaling pathway involved in determination of adult lifespan The series of molecular signals generated as a consequence of the insulin receptor binding to insulin that controls viability and duration in the adult phase of the life-cycle. go.json daf-2 receptor signaling pathway of determination of adult lifespan|insulin receptor signalling pathway of determination of adult lifespan|insulin receptor signaling pathway of determination of adult lifespan http://purl.obolibrary.org/obo/GO_1901047 GO:1901044 biolink:BiologicalProcess protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process Any protein polyubiquitination that is involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process. go.json http://purl.obolibrary.org/obo/GO_1901044 GO:1901045 biolink:BiologicalProcess negative regulation of oviposition Any process that stops, prevents or reduces the frequency, rate or extent of oviposition. go.json downregulation of oviposition|inhibition of oviposition|inhibition of egg-laying|downregulation of egg laying|downregulation of egg-laying|down regulation of egg laying|down-regulation of oviposition|down regulation of egg-laying|down-regulation of egg laying|negative regulation of egg laying|down regulation of oviposition|down-regulation of egg-laying|negative regulation of egg-laying|inhibition of egg laying http://purl.obolibrary.org/obo/GO_1901045 GO:1901053 biolink:BiologicalProcess sarcosine catabolic process The chemical reactions and pathways resulting in the breakdown of sarcosine. go.json sarcosine degradation|sarcosine catabolism|sarcosine breakdown http://purl.obolibrary.org/obo/GO_1901053 GO:1901054 biolink:BiologicalProcess sarcosine biosynthetic process The chemical reactions and pathways resulting in the formation of sarcosine. go.json sarcosine anabolism|sarcosine synthesis|sarcosine biosynthesis|sarcosine formation http://purl.obolibrary.org/obo/GO_1901054 GO:0036510 biolink:BiologicalProcess trimming of terminal mannose on C branch The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. go.json conversion of M9 to M8C|conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2|glycoprotein mannose trimming on C branch http://purl.obolibrary.org/obo/GO_0036510 GO:1901051 biolink:BiologicalProcess atropine biosynthetic process The chemical reactions and pathways resulting in the formation of atropine. go.json atropine formation|atropine biosynthesis|atropine anabolism|atropine synthesis http://purl.obolibrary.org/obo/GO_1901051 GO:0036511 biolink:BiologicalProcess trimming of first mannose on A branch The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. go.json conversion of (Man)9(GlcNAc)2 to (Man)8A(GlcNAc)2|conversion of M9 to M8A|glycoprotein mannose trimming on A branch http://purl.obolibrary.org/obo/GO_0036511 GO:1901052 biolink:BiologicalProcess sarcosine metabolic process The chemical reactions and pathways involving sarcosine. go.json sarcosine metabolism http://purl.obolibrary.org/obo/GO_1901052 GO:0036512 biolink:BiologicalProcess trimming of second mannose on A branch The removal of the second alpha-1,2-linked mannose from the A-ch