id subject predicate object category relation description has_attribute source uuid:8ffe64b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:8ffe971a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:8ffec0a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:8ffee59e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:8fff0b14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.707']} DrugCentral uuid:8fff3472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:8fff595c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:8fff82b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) DrugCentral uuid:8fffabdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:8fffabdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:8fffdb20-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:90000488-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:90002df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90005820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90008174-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9000aad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:9000d070-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:13 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levdobutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:9000f546-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:90011e2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:90014708-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:90017034-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48760 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Folylpoly-gamma-glutamate synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:90019924-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:9001c1ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:9001eadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:90021552-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:90023f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:90026a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:25 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:900292ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:25 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:9002b7b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:9002dbfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:90030034-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96J66 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Transporter (ATP-binding cassette sub-family C member 11) DrugCentral uuid:90032492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:90034d8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8F0 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Enzyme (Uracil phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9003764a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O26232 biolink:molecularly_interacts_with DrugCentral:27 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:90039ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03962 biolink:molecularly_interacts_with DrugCentral:27 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9003c834-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9003f264-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:90041c30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:900444da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:90046d70-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:900496b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.276']} DrugCentral uuid:9004bf50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9004e7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:900510e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:35 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.49']} DrugCentral uuid:90054196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:90054196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:90054196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:900590ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:900590ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:900590ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:900590ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:900590ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:900590ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:900590ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:9005f172-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.697']} DrugCentral uuid:900619fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose is inhibitor of Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:90063e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90066760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:90069000-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9006b88c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9006e136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P94451 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:90070a26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53051 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Oligo-1,6-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:9007329e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00690 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:90075b0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:90078492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9007af1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9007d7bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:90080052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:90082960-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:900851ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.227']} DrugCentral uuid:90087ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:90089ed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9008c79e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9008f03e-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:900918c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:90093e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:900963ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:90098e86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:48 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acenocoumarol is inhibitor of Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9009b6f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:48 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acenocoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.114']} DrugCentral uuid:9009df6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:49 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:900a0988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:50 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceprometazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:900a2ddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:900a565e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:900a7a6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:900a9ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:900ac774-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:900af000-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:900b1896-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:900b4262-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:900b6aee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:900b9384-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:900bbc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:900be546-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:900c0dbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.547']} DrugCentral uuid:900c362c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:900c5ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:900c87d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02144 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Unclassified (Myoglobin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:900cb03e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is agonist of GPCR (Cannabinoid receptor 1) DrugCentral uuid:900cd456-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:54 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetanilide targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:900cfcce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:900d27ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:900d5098-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:900d794c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:900da2a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:900dcb2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:900df3c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:900e1d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29972 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Transporter (Aquaporin-1) DrugCentral uuid:900e4174-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:900e69f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:900e9278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:900ebb18-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:900ee548-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:900f0df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:900f3822-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:900f60ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:900f8a52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:900fb310-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERQ8 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:900fdb92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:90100428-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:90102d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:90105590-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:90107e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9010a6b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9010d060-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9011239e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:90114ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9011757e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:90119df6-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:9011c682-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9011ef40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:901217b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:90124030-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:90126998-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:90129314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9012bba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90130e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9013bcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9013bcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9013bcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9013bcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:90140c3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:90140c3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:90143ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46510 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:90146950-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.08']} DrugCentral uuid:901491c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:9014ba72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HVB9 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9014e48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:90150eb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:901537cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75493 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase-related protein 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:9015644a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:9015644a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:9015982a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:9015c886-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:9015c886-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:9015c886-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:90160012-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:90162916-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0PXQ5 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Urease subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:901653aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:59 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetophenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:901677e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:59 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetophenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9016a0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9016c9fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril is inhibitor of Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9016f260-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:90171ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:9017430a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08049 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:90176ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19621 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:901793fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42892 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Endothelin-converting enzyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9017bc72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00800 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Thermolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9017e4e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:90180e7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:901836de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:90185f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9018879c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9018b064-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:9018d9b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9019021c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:90192ab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9019546a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:90197cd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9019a51e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9019cd78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9019f9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:901a23ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:901a5054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:901a5054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:901a8812-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:901a8812-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:901abf80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:901abf80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:901af70c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:901af70c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:901b2f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:901b2f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:901b66f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:901b66f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:901bab3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:901bab3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:901bab3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:901bab3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:901bab3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:901c0598-dc5e-11ec-be2c-0242ac110005 UniProtKB:H6TY12 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Nicotinic acetylcholine receptor alpha8 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:901c2dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P99999 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Enzyme (Cytochrome c) DrugCentral uuid:901c5246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Secreted (Vascular endothelial growth factor A) DrugCentral uuid:901c7654-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04179 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Enzyme (Superoxide dismutase [Mn], mitochondrial) DrugCentral uuid:901c9a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48637 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine is modulator of Enzyme (Glutathione synthetase) DrugCentral uuid:901cbe7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine is modulator of Transporter (Cystine/glutamate transporter) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901cfdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:901d67c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:901d8d14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:901db118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:901dd968-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:901e01e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:901e2a6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60045 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Acidic phospholipase A2 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:901e52d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19440 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:901e7b16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:901ea370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:901ecc06-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:901ef44c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:901f1c92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:901f460e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:76 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acipimox is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:901f71e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:901f97c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:901fc02a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) DrugCentral uuid:901fe42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:90200cec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:9020353c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:90205d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:9020858c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:9020858c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:9020c312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:9020c312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:9020c312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:9020c312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:9020c312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:90210da4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:90213388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:90215ce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:90218522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9021ad7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Kinase (Thymidine kinase) DrugCentral uuid:9021d1e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9021fa34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:902222a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:90224692-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:90226af0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:90228eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04407 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:9022b3fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9022dc74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:902306b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:90233048-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:902358c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil is inhibitor of Polyprotein (Protein P) DrugCentral uuid:90237ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54098 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil targets Enzyme (DNA polymerase subunit gamma-1) DrugCentral uuid:9023a0f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9023c922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9023fcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9023fcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9023fcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9023fcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:902446e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:90246f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.509']} DrugCentral uuid:90249762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:9024bfa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9024eb0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9025164c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:902540a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:902568f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9025918a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9025b9a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9TVW2 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9025e220-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:90260ab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23526 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.796']} DrugCentral uuid:902636e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:902636e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:90266a74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BTU6 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:902692c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCG2 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9026bd9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04406 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Glyceraldehyde-3-phosphate dehydrogenase liver) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:9026f250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9026f250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9026f250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9026f250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:90273c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TEK3 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Histone-lysine N-methyltransferase, H3 lysine-79 specific) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9027651e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49652 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:90278d5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:9027b5fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9027dfd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:90280834-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:90283066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:902858c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:902882a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9028ab22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9028d386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41148 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Membrane other (Endoplasmin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9028fbc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49137 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (MAP kinase-activated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:90292494-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:90294cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:90297534-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:90299d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.836']} DrugCentral uuid:9029c642-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12931 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock protein 75 kDa, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9029eeba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:902a1732-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:902a3f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:902a69ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:902a931a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:902abb60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJX6 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:902ae39c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:902b0c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:902b3482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51579 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:902b5caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:902b8522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:902bad90-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:902bd5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09467 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:902bfe3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00636 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:902c2810-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:902c5218-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:902c7a54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:902ca290-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:902ccf22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:902ccf22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:902d02bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.19']} DrugCentral uuid:902d2b20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A9J4 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Ketopantoate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.2']} DrugCentral uuid:902d537a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:902d7d82-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43598 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:902da654-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35820 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:902dceb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902e291c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:902ec322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:902efac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:902efac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:902efac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:902efac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:902efac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:902f4fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:902f783a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:902fa490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:902fa490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:902fe0ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:902fe0ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:902fe0ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:90301f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:903047d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:903070aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:90309918-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9030bd1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9030e67a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:90310f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:903137a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alacepril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:90315fa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:90315fa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:903192be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:903192be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:9031c324-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole targets Structural (Tubulin alpha chain) DrugCentral uuid:9031ef20-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:9031ef20-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:9031ef20-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90323dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90323dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90323dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90323dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90323dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90323dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90323dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:90329bb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:104 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole sulfoxide targets Structural (Tubulin alpha chain) DrugCentral uuid:9032bfb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.613']} DrugCentral uuid:9032e8f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:9033117a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:903339de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:90336242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:903387b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclofenac targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:9033abbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:9033d416-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9033fc70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9034251a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:90344d60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.721']} DrugCentral uuid:90347718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:90349f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9034cfb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:9034cfb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:9034cfb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:90350ade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:90350ade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:90353e28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9035679a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:90358fe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9035b83a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:9035e076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:90360a42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9036327e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Protein farnesyltransferase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:90365a88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:90368314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9036ab50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9036d3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9036fbf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:903725da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WUK0 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine is inhibitor of Enzyme (Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:90374f10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9037772e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.951']} DrugCentral uuid:90379f56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9037c7d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9037fb72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9037fb72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9037fb72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9037fb72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:903847b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:903870d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:9038992e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:9038c160-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:9038e99c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:903912dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:90393b2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:90396386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.61']} DrugCentral uuid:90398bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:9039b502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9039dd2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9TSZ1 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:903a0552-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6DLS0 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:903a2e9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08424 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:903a56e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06281 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:903a7eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7M3D2 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:903aa70a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:903ad0f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6DLW5 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:903af930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:903b2180-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:903b49d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:903b72d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:903b9c3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:903bc02c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:903be872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:903c1270-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9FBI2 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Unclassified (Shiga toxin subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:903c3ab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:903c6306-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:903c8b6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:903cb554-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:903cdd86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:903d05d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:903d2e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.218']} DrugCentral uuid:903d5720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfacalcidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:903d7f7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfacalcidol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:903da356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Transporter (Sodium- and chloride-dependent GABA transporter 1) DrugCentral uuid:903dced0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:903dced0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:903dced0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903e477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:903f20d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:903f20d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:903f20d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:903f5f34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:903f8770-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:903fb178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9040e2b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:90410af0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Unclassified (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9041334a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem is partial agonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) DrugCentral uuid:90415730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:90417fda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.457']} DrugCentral uuid:9041a8b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:9041d0e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.61']} DrugCentral uuid:904200e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:904200e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:904200e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:90424b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:90424b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:90424b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:904295d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:904295d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:904295d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:9042dc2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9042dc2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9042dc2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:90431a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:904342a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:90436cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:904395d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:9043be08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9043e626-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:904411a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:90443c2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.678']} DrugCentral uuid:9044648e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.658']} DrugCentral uuid:90448d60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9044b57e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9044dd7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:904505a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:90452f86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:90455ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:904582f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9045ab28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9045d422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9045fcf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:90462530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:90464d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:904675ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:90469e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9046c634-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9046ee5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:90471710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:90473f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.35']} DrugCentral uuid:90476774-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:904790a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 altretamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:9047bb8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:9047e3d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:90480c9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:90483514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:90485d64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:904885aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:9048ade6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is inhibitor of Ion channel (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9048edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9048edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9048edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9048edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9048edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9048edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9048edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:90495a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q20MD5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:90498388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9049ac00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9049d446-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:9049f840-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.34']} DrugCentral uuid:904a2158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:904a4994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:904a71f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.254']} DrugCentral uuid:904a9a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:904abe88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:904ae6ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:904b1356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:904b1356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:904b1356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:904b5a14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:904b5a14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:904b5a14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:904b9862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifostine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:904bc094-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifostine targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) DrugCentral uuid:904be538-dc5e-11ec-be2c-0242ac110005 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amikacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.201']} DrugCentral uuid:904c0d88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37088 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Amiloride-sensitive sodium channel subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:904c35ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:904c5dec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:904c8682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.408']} DrugCentral uuid:904caebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19634 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:904cd6e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:904cff22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:904d2862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:904d509e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:904d7966-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:904da954-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:904da954-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:904da954-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:904de8d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9W6Q1 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:904e1240-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14940 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:904e3a9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26431 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:904e640c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50482 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:904e8c70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06869 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:904eb4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55926 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:904edd06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:904f0600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:904f2e46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:904f568c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amineptine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:904f7ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminocaproic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:904fa7c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminocaproic acid is inhibitor of Enzyme (Tissue-type plasminogen activator) DrugCentral uuid:904fcba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:904ff3e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:90501c3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:905040b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:905068ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:905090f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9050b978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9050e4f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:90510b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:90512f70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:905157b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopicoline is inhibitor of Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:905180b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9051a900-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:9051d150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9051fa0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9052224a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:90524a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:905273a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:90529d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9052c8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.177']} DrugCentral uuid:9052f33c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:90531b78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9053444a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:90536c90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:90539558-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9053bd94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9053e742-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:90540f88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:905437ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:90546046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:90548a26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.989']} DrugCentral uuid:9054b28a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:9054daee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.674']} DrugCentral uuid:9055033e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.045']} DrugCentral uuid:90552bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9055542e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:90557c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.984']} DrugCentral uuid:9055a532-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:9055cd8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:9055f65e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.168']} DrugCentral uuid:90561ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.296']} DrugCentral uuid:905648a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.968']} DrugCentral uuid:905673cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.498']} DrugCentral uuid:90569c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:9056c480-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.004']} DrugCentral uuid:9056ed2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:9057157a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.176']} DrugCentral uuid:90573dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.549']} DrugCentral uuid:9057662e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:90578ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.284']} DrugCentral uuid:9057b6f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.791']} DrugCentral uuid:9057df46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:90580782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:90583266-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.039']} DrugCentral uuid:90585aa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37268 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:905882de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.368']} DrugCentral uuid:9058ab24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:9058d3ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9058fc3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:90592478-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.347']} DrugCentral uuid:90594d18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:905975d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.407']} DrugCentral uuid:90599e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:9059c66c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.879']} DrugCentral uuid:9059f196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:905a1a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:905a4254-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.943']} DrugCentral uuid:905a6b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.932']} DrugCentral uuid:905a9434-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:905abc84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:905ae4de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:905b0d1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:905b35b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75151 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase PHF2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:905b5e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:905b866e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6ZMT4 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:905bae8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.953']} DrugCentral uuid:905bd84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:905c009e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:905c28ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.382']} DrugCentral uuid:905c5134-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:905c79de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.758']} DrugCentral uuid:905ca21a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:905cca60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:905cf29c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:905d1b46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:905d4396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:905d6bfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:905d95b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:905dbe52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:905de6ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:905e0efc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:905e37c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:905e60c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:905e8918-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.367']} DrugCentral uuid:905eb15e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.456']} DrugCentral uuid:905ed9fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:905f0230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:905f2a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:905f52d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:905f7c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:905fa44c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:905fcc9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:905ff5dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:90601f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:9060474e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:90606f9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:906097da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9060c084-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:9060e8d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.83']} DrugCentral uuid:90611124-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:90613974-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:90616494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:90618cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9061b534-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:9061ddd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.066']} DrugCentral uuid:90620642-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:90622e92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:906257e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:90628086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:9062a8e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9062d11c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:9062f962-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:90632388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:90634cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:906374fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:90639d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9063c608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9063ee4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:906416a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:90643eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:90646784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:90648fe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9064b824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:9064e06a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:906509fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:90654168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90654168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90654168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90654168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90654168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:906597da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9065c016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptylinoxide targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9065e960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:906611b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90663a50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:90666df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:90666df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:90666df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:90666df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:9066aed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.646']} DrugCentral uuid:9066da1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:906702fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:90672b2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9067535e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:90677c44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.358']} DrugCentral uuid:9067a48a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9067ccc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9067f57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:90681dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:906841ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:906865dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:90688ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9068b852-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.507']} DrugCentral uuid:9068e0ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:906908e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:906931ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:90695a28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:90698250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50135 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9069ab72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y251 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Enzyme (Heparanase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9069d412-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9069fc30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:906a248a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:906a4cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:906a762e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:906a9a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:906ac296-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:906aec12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:906b1502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:906b3d5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.182']} DrugCentral uuid:906b65a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:906b8dfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:906bb6c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:906bdf1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:906c0778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.734']} DrugCentral uuid:906c2fbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:906c58fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.542']} DrugCentral uuid:906c814e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:906ca994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:906cd25c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.616']} DrugCentral uuid:906cfbba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.211']} DrugCentral uuid:906d2414-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:906d4c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.365']} DrugCentral uuid:906d74fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:906d9d40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:906dc694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:906deeee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:906e18ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y345 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Sodium- and chloride-dependent glycine transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:906e42fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:906e6b3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:906e938a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:906ebc7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:906ee4d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:906f0d10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:906f3ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:906f3ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:906f3ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:906f74f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:906f9d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:906fc570-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:906fef46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:90702b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90702b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90702b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90702b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90702b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90702b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90702b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90708b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amperozide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9070b35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amperozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:9070dba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:9070ff94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.753']} DrugCentral uuid:90712852-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:90714d28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:90717122-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:90719954-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:9071be8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9071e6de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:90720f38-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9072377e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072605a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:90728882-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9072e1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9073a5c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9073a5c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9073a5c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9073a5c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9073f848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:9073f848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:9073f848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:9074393e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:90746166-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:9074856a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9074adc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:9074ed3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9074ed3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9074ed3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9074ed3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9074ed3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9074ed3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9074ed3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90754b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:907575b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:90759a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.172']} DrugCentral uuid:9075c268-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9075ea9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:90761358-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:90763b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:907663d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:90768c2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:9076b4c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9076dcfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:90771082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:90771082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:90771082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:90771082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:90775e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9077867a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9077aeb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9077d77e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9077ff9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:907827a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:90784fd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:90787c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:90787c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9078af64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagrelide is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:9078d796-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagrelide targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:9078ffd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anastrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:90792ab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androisoxazole targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:90794e92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:907976b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:90799ed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9079c7aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9079efe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.17']} DrugCentral uuid:907a1836-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:907a405e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:907a68d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:907a919e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:907abac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:907ae40a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:907b0f3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54939 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:907b3748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anecortave targets Secreted (Plasminogen activator inhibitor 1) DrugCentral uuid:907b5b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:907b7fdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:907ba3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:907bc762-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:907beb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Structural (Tubulin beta-4B chain) DrugCentral uuid:907c0f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anileridine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:907c336e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P38435 biolink:molecularly_interacts_with DrugCentral:222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anisindione is inhibitor of Enzyme (Vitamin K-dependent gamma-carboxylase) DrugCentral uuid:907c575e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anisindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:907c7f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:907ca380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:907cc9be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 antazoline is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:907ceea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 antazoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:907d16d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75342 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Arachidonate 12-lipoxygenase, 12R-type) DrugCentral uuid:907d3ac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:907d637e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:907d8bec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:907db450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:907ddc64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:907e0522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:907e2d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:907e55a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:907e7dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:907ea838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:907ed1b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:907efad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:907f23a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:907f4c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:907f74b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:907f9cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:907fc59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:907fee64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:908016b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:90803ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:90806a10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:90809260-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9080ba9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9080e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:90810bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9081342c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:90815c7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:908184ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9081adbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9081d60c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9081fe3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:90822670-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:90825bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90825bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90825bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90825bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9082d7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:90839a00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:90839a00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:90839a00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9083dc4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9083dc4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:90842038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:90842038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:90842038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:90842038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:90842038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:90847c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:90847c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:90847c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9084bc3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34949 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Enzyme (Mannose-6-phosphate isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:9084e478-dc5e-11ec-be2c-0242ac110005 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:90850cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:90853504-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:90855da4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.938']} DrugCentral uuid:90858612-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9085ae6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:9085dfb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9085dfb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9085dfb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:90861f78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:9086437c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:90866bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:90869502-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5DUB1 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:9086bd34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9086e138-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:90870546-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.757']} DrugCentral uuid:90872df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:90875622-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32418 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Transporter (Sodium/calcium exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:90877e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.359']} DrugCentral uuid:9087aef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:9087aef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:9087aef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:9087f4e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9087f4e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:90882390-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:90884780-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:9088700c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:90889852-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:9088c08e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9088e938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00735 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:9089117e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.851']} DrugCentral uuid:908939ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:9089620a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:90898bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:9089b516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.131']} DrugCentral uuid:9089dd52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:908a0584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:908a2df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:908a5624-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:908a7e88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:908aa69c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:908acf1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:908af778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:908b1f96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:908b47d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:908b7202-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.991']} DrugCentral uuid:908b9a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:908bc25c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.681']} DrugCentral uuid:908bea84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:908c1310-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.169']} DrugCentral uuid:908c3c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:908c6464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:908c8c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:908cb540-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.633']} DrugCentral uuid:908cdd7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:908d05a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:908d2ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.421']} DrugCentral uuid:908d5a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:908d8470-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:908dadc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.202']} DrugCentral uuid:908dd65a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.463']} DrugCentral uuid:908dfe8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:908e26c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:908e4efa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:908e77a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:908ea0da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:908ec92a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:908ef17a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:908f1b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:908f43e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:908f6c36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:908f9490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:908fbd30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:908fe59e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:90900e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9090376a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9090601e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arsenic trioxide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:90908878-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arsenic trioxide is inhibitor of Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:9090ac72-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.312']} DrugCentral uuid:9090d4c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.998']} DrugCentral uuid:9090fe20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:9091267a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:90914ee8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:909177b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.741']} DrugCentral uuid:9091a00a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:9091c850-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:9091f082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:9092197c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:909241b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:90926a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:90929276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:9092bc24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:9092e47e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.126']} DrugCentral uuid:90930ce2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.027']} DrugCentral uuid:9093353c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:90935e36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:909387a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:9093b002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:9093d85c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:909401f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:90942b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:909453a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:90947c6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:9094a782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.297']} DrugCentral uuid:9094cfbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:9094f818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:909520cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:9095491c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:9095713a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:9095998a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:9095c22a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:9095ea70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:90961298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:90963660-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:90966720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90966720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90966720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9096a582-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9096cdbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9096f6d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:90971efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:9097474e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.701']} DrugCentral uuid:90976f76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.546']} DrugCentral uuid:9097980c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.883']} DrugCentral uuid:9097c034-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:9097e87a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:909811ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:90983c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:90986642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:90988e88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.673']} DrugCentral uuid:9098b6c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.868']} DrugCentral uuid:9098dfd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:90990818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:90993036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9099599e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:9099861c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9099861c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9099b952-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:9099e198-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:909a0b50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:909a35bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.58']} DrugCentral uuid:909a5dda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asulacrine targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:909a81c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:909aaa9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:909ad364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:909afb96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:909b23dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.575']} DrugCentral uuid:909b4c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:909b74f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:909b9d26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:909bc576-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:909bee66-dc5e-11ec-be2c-0242ac110005 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.27']} DrugCentral uuid:909c179c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.12']} DrugCentral uuid:909c3fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:909c6814-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:909c910e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:909cb936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:909ce1ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:909d0a3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:909d32d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:909d5b0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:909d8366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.69']} DrugCentral uuid:909dacce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:909dd50a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:909dfd50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.282']} DrugCentral uuid:909e2582-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:909e4e4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:909e7686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:909e9fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:909ecbcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:909ecbcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:909f034e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:909f034e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:909f37e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:909f600a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:909f84d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:909fad12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:909fd648-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:909ffe7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90a027ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:90a04fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:90a0780a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q1W675 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:90a0a050-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:90a0c8c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43264 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial) DrugCentral uuid:90a0ed58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02768 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone is inhibitor of Enzyme (Cytochrome b) DrugCentral uuid:90a1112a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:90a13970-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:90a1626a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:90a18664-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:90a1aea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:90a1de84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:90a1de84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:90a1de84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:90a21dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:90a24608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:90a26e76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:90a2970c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:90a2bf5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:90a2e798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:90a30fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:90a33a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:90a3625e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:90a38b80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:90a3b3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:90a3dc98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:90a404de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:90a42d10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:90a45556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:90a47e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:90a4a68c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:90a4cffe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:90a4f862-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:90a5217a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:90a549b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:90a571fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:90a59ae2-dc5e-11ec-be2c-0242ac110005 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:90a5d26e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:90a5d26e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:90a5d26e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:90a5d26e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:90a5d26e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:90a626f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:90a65766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:90a65766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:90a65766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:90a69df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:90a69df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:90a69df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:90a6df38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapropazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:90a705ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapropazone targets Enzyme (Xanthine dehydrogenase/oxidase) DrugCentral uuid:90a72cd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:90a7574c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azatadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:90a77bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:90a7a40e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:90a7c7f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:90a7ebd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:90a81024-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63000 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Enzyme (Ras-related C3 botulinum toxin substrate 1) DrugCentral uuid:90a83400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:90a857e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelaic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) DrugCentral uuid:90a87bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:90a8a476-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:90a8c92e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:90a8f174-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:90a919ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90a94282-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.168']} DrugCentral uuid:90a96ac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:90a992fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90a9bb4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:90a9e55c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90aa118a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:90aa118a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:90aa3f16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:90aa675c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08703 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:90aa904c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70344 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:90aab892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:90aae1aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.39']} DrugCentral uuid:90ab09c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.7']} DrugCentral uuid:90ab324a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:90ab5a7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:90ab9596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:90ab9596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:90ab9596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:90ab9596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:90ab9596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:90ab9596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:90abea32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:90ac128c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:90ac3adc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.317']} DrugCentral uuid:90ac6584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:90ac8e10-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:90acb638-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:90acdeec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q83TT7 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Unclassified (AmpC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:90ad07fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:90ad3086-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:90ad58ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:90ad80d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:90adc046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90adc046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90adc046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90adc046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90adc046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90adc046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90adc046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:90ae1ee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:90ae4a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.716']} DrugCentral uuid:90ae736a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:90ae9cd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60932 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Unclassified (Undecaprenyl-diphosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:90aec982-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90aec982-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af00b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:90af00b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:90af33cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90af94de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90b06594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:90b08970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:90b0ae00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:90b0d1e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:90b0f590-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:90b11958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:90b141b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.25']} DrugCentral uuid:90b169d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:90b191e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:90b1b9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bamipine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:90b1e2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:90b1e2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:90b21042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:90b23860-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:90b26088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:90b28aae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90b2b2a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:90b2daae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:90b302cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:90b32bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:90b353e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Y34 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate is agonist of GPCR (Probable G-protein coupled receptor 97) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:90b37c02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:90b3a52e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90b3cdd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belotecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.561']} DrugCentral uuid:90b3f600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:90b41e28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:90b446c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:90b46fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:90b497cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:90b4bff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:90b4e862-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:90b51076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:90b538a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:90b560bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:90b58542-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.3']} DrugCentral uuid:90b5ad24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:90b5d0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:90b5f4b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:90b61930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benoxaprofen is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:90b63cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benoxaprofen targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:90b66516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.57']} DrugCentral uuid:90b68d5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:90b6b5de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:90b6dde8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:90b7061a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:90b72e4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:90b757d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:90b78162-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:90b7a976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:90b7d18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:90b7fa3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:90b82266-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:90b84bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:90b874c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:90b89d9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:90b8c5c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.486']} DrugCentral uuid:90b8edcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:90b91db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:90b91db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:90b91db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:90b95c94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:90b980e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:90b9a8d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:90b9d53e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:90b9d53e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:90ba0856-dc5e-11ec-be2c-0242ac110005 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:90ba3074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03313 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Unclassified (Genome polyprotein [Cleaved into: P1; Capsid protein VP0) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:90ba5932-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52789 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Kinase (Hexokinase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:90ba8146-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzarone targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:90baa95a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:90bad178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:90bafacc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:90bb2312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:90bb4b3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:90bb7344-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:90bb9ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:90bbc3c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:90bbebd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.908']} DrugCentral uuid:90bc14c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.711']} DrugCentral uuid:90bc3d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:90bc6556-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:90bc8d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.32']} DrugCentral uuid:90bcb588-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:90bcdefa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:90bd0722-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:90bd2f36-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15392 biolink:molecularly_interacts_with DrugCentral:321 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benziodarone targets Unclassified (Baculoviral IAP repeat-containing protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:90bd5768-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:321 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benziodarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:90bd7fd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:90bda3b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:90bdc784-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:90bdec82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:90be10fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:90be34da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:90be5942-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:90be7d0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:90bea1f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01118 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 7 subunit alpha) DrugCentral uuid:90bec792-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['3.495']} DrugCentral uuid:90beef88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzonatate targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:90bf1346-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:90bf3736-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:90bf5b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:90bf7f16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:90bfa306-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:90bfcb24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:90bff3e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.445']} DrugCentral uuid:90c01bf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:90c04522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:90c06d36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:90c098a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:90c0c0a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:90c0e46e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.17']} DrugCentral uuid:90c10c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:90c13072-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:90c15430-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:90c1780c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:90c1a03e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:90c1c910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:90c1f11a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:90c21942-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.157']} DrugCentral uuid:90c2414c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:90c26a5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:90c29296-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:90c2bac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:90c2e32c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.654']} DrugCentral uuid:90c30b5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:90c33386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:90c35bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.636']} DrugCentral uuid:90c385ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:90c3adfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:90c3d61a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:90c3fe4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:90c42750-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:90c45068-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.253']} DrugCentral uuid:90c47908-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:90c4a13a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:90c4c9bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:90c4f1ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:90c519ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:90c541ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:90c56aa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:90c592e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:90c5bb06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:90c5e338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzyl benzoate targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:90c60dcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzyl benzoate targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:90c635f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepotastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:90c6599e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:90c67d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:90c6a5c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:90c6cdf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.149']} DrugCentral uuid:90c6f624-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:90c71e24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:90c746ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:90c76ef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:90c79ebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:90c79ebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:90c79ebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:90c7df8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is gating inhibitor of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90c80b5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:90c82f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:90c85302-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:90c87b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:90c8a3ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:90c8cbd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:90c8f3f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:90c91c38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2Q167 biolink:molecularly_interacts_with DrugCentral:345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betacarotene targets Unclassified (Core protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:90c9458c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betahistine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:90c96db4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betahistine is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:90c995d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:90c9bf1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:90c9e2ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:90ca06a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone benzoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:90ca2a6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:90ca4efa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:90ca7722-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:90ca9ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:90cac2e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:90caeb76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:90cb1402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:90cb3c48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:90cb647a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:90cb8ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.53']} DrugCentral uuid:90cbb718-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:90cbdf4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betazole is agonist of GPCR (Histamine H2 receptor) DrugCentral uuid:90cc0326-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:90cc2cac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:90cc54de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:90cc7d1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:90cca542-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:90cccdc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VH27 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol targets GPCR (Muscarinic receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90ccf5d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betanidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:90cd19b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bevantolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:90cd3d72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:90cd67f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:90cd902e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:90cdb874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:90cde10a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:90ce0b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90ce33bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:90ce5be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:90ce8466-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:90ceac8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:90ced48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:90cefcac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43174 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:90cf27fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR63 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:90cf5094-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:90cf7970-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:90cfa166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Enzyme (Lipoprotein lipase) DrugCentral uuid:90cfc59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:90cfedce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:90d016dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:90d03f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:90d067a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:90d08fd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) DrugCentral uuid:90d0b394-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:90d0d752-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:90d0fc78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:90d12054-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:90d14408-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:90d167ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:90d19098-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90d1b8b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:90d1e0de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:90d208fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:90d2314c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:90d25988-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifemelane targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:90d2820a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:90d2aa32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:90d2d3b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:90d2fbcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:90d32480-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bimatoprost targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:90d34c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bimatoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:90d3752a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biotin targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:90d39d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.32']} DrugCentral uuid:90d3c5f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:90d3ee06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:90d4175a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:90d43f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:90d4678c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:90d48b7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:90d4b6ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:90d4e1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:90d509c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisantrene targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:90d5322a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:90d55a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:90d582a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:90d5aab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:90d5d356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:90d5fb7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisulepine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:90d61f78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bitolterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:90d64354-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bivalirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:90d66cbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:90d696a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:90d6bef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.854']} DrugCentral uuid:90d6e728-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:90d70faa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:90d737be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:90d75ff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.014']} DrugCentral uuid:90d7880e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:90d7b07c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.262']} DrugCentral uuid:90d7d85e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:90d8007c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:90d8298a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:90d852d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:90d87b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:90d8a34c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:90d8cb88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:90d8f478-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:90d91ca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:90d944c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:90d96ce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:90d99572-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:90d9bd90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:90d9e5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99460 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Cytosolic other (26S proteasome non-ATPase regulatory subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:90da0e1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.208']} DrugCentral uuid:90da3888-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:90da6092-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:90da88ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:90dab164-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:90dadacc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:90db02f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:90db2b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:90db53a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:90db7bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:90dba3bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:90dbcbe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:90dbf59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:90dc2044-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:90dc4966-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:90dc71b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:90dca08c-dc5e-11ec-be2c-0242ac110005 UniProtKB:A5PKW4 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Unclassified (PH and SEC7 domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:90dcd05c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:90dcd05c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:90dcd05c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:90dd0eb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:90dd3754-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IJT1 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:90dd5f9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28063 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.78']} DrugCentral uuid:90dd87cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:90ddafea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:90ddd9de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:90ddfd9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:90de25d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:90de4e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:90de76dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:90de9f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q29010 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:90dec704-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:90deeef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21451 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:90df174a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:90df3aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:90df5ebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:90df8284-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:90dfabf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:90dfd496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:90dffcc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:90e025cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:90e04e80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:90e07694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:90e0a010-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:90e0c838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:90e0f0d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:90e12076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90e12076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90e12076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90e1669e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:90e1669e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:90e1669e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:90e1a672-dc5e-11ec-be2c-0242ac110005 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:90e1cea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:90e1f6d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:90e21f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:90e2478a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:90e26fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:90e297c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90e2c048-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90e2e852-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:90e31066-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:90e33884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:90e362a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:90e38aaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:90e3b2d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:90e3dc4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:90e4048a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:90e42cbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:90e45516-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:90e47da2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:90e4a5f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:90e4ce1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:90e4f660-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:90e5211c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:90e54944-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:90e571e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:90e59a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:90e5c2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:90e5eaf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:90e6131a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:90e63c64-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:90e664e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:90e68d04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:90e6b50e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06479 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90e6dd18-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:90e7078e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:90e72fa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:90e757a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:90e77f8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:90e7a82e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:90e7d132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:90e7f950-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:90e821aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:90e85170-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:90e85170-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:90e85170-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:90e8887a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:90e8b0a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:90e8dec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:90e8dec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:90e911e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:90e93a18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:90e9629a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:90e98acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:90e9b2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.858']} DrugCentral uuid:90e9dafe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:90ea036c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:90ea2b94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:90ea53b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:90ea7bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:90eaa48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:90eaccac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:90eaf4c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90eb1cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:90eb45ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:90eb6dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:90eb96dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:90ebc06c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:90ebe90c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:90ec11c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:90ec39e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:90ec6224-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:90ec8b00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:90ecb33c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:90ecdb5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:90ed0454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:90ed2c7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:90ed54b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:90ed7cc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:90eda53a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:90edcd4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:90edf594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:90ee1d9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:90ee472e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:90ee7712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:90ee7712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:90ee7712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:90eec492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90eec492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90eec492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90eec492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90eec492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90ef1eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:90ef1eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:90ef520e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:90ef7acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:90efa2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:90efcb08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:90eff344-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:90f01c34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:90f0443e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:90f06c52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:90f0948e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:90f0bcfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:90f0e524-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.745']} DrugCentral uuid:90f10e78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:90f13682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:90f15f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.319']} DrugCentral uuid:90f1877c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:90f1afb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:90f1d7e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.218']} DrugCentral uuid:90f209d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:90f209d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:90f209d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:90f24806-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brotizolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:90f27042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:90f299aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buclizine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:90f2bd72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:90f2e14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:90f30958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:90f3320c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:90f35a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:90f382ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:90f3aaac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.701']} DrugCentral uuid:90f3d4dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:90f3fd0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:90f42536-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:90f44d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:90f475cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:90f4b4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90f4b4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90f4b4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90f4b4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90f4b4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90f4b4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90f4b4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:90f51f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:90f5434e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:90f56b80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:90f594e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:90f5bb44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:90f5e114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:90f605fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:90f62b10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:90f64f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:90f6771e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:90f69f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:90f6c822-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:90f6ebea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.59']} DrugCentral uuid:90f71426-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:90f73c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:90f7658e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:90f78eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:90f7b6b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:90f7da64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:90f7fe90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:90f82244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:90f84620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.399']} DrugCentral uuid:90f86e7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.263']} DrugCentral uuid:90f896ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:90f8bf6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:90f8e79c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:90f90fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:90f938f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:90f96168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:90f98990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:90f9b1d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:90f9da3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:90fa02b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.293']} DrugCentral uuid:90fa2b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90fa5398-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:90fa7c4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:90faa456-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.233']} DrugCentral uuid:90facc7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:90faf492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:90fb1ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:90fb4708-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z0V1 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:90fb6f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:90fb9730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:90fbbfc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:90fbe92e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:90fc1156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:90fc3974-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:90fc6232-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:90fc8a6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:90fcb2aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:90fcdaf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:90fd0480-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:90fd2cbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:90fd54ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:90fd7d70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:90fda5a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:90fdcdca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.796']} DrugCentral uuid:90fdf688-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:90fe2040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:90fe441c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:90fe6c30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:90fe943a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:90febdc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:90feecd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:90feecd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:90ff26d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90ff26d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:90ff5a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.569']} DrugCentral uuid:90ff826e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.52']} DrugCentral uuid:90ffaa82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01776 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:90ffd282-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:90fffb40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:91002372-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:91004be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:9100741c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:91009d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9100c570-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9100ed7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:91011598-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.435']} DrugCentral uuid:91013e1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:91016624-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:91018e2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.277']} DrugCentral uuid:9101b76e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9101e108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.471']} DrugCentral uuid:91020926-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:91023144-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9102598a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:9102839c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9102abba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9102d3d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9102fc78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:910324dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:91034ce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:910374dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:91039dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9103c5cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9103edf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:910415f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:91043ed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:91047242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:91047242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:91047242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:91047242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9104c328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9104c328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9104c328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:910510f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:910510f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:910510f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:910510f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:910510f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:91056efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:91056efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:91056efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:9105b54e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:9105b54e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:9105b54e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:9105f3a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 busulfan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.283']} DrugCentral uuid:910624b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:910624b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:910624b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:91066502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:91066502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:91066502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:91069c48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:9106c4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:9106ed88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:910715c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:91073de2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:9107666e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.161']} DrugCentral uuid:91078e6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:9107b24a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.805']} DrugCentral uuid:9107db30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:91080682-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92206 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.347']} DrugCentral uuid:91083166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:9108554c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:91087e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:9108a646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9108ce64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:9108f678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:91091ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.405']} DrugCentral uuid:9109470e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:91096aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:91098e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:9109b360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:9109d8d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:910a0112-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:910a2958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:910a5234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:910a7a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:910aa2a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:910acad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:910af360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:910b1b9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:910b43c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:910b6c00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:910b9522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:910bbd4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:910be68a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:910c0eb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:910c386a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:910c609c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:910c88ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cadralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:910cac8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cadralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:910cd50e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:910cfd36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:910d255e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:910d4da4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:910d791e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:910da150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:910dc96e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:910df18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:910e1a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:910e4268-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:910e6a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:910e9326-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:910ebf22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:910ebf22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:910efdd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:910efdd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:910efdd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:910efdd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:910f4a00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2T3 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Guanine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:910f7430-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:910f9c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:910fc494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcifediol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:910fea00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:465 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcipotriene is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:91101232-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:91103604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:91105e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:91108244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02774 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Secreted (Vitamin D-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9110aa6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9110d280-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42392 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.6']} DrugCentral uuid:9110fabc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28037 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:911125d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3RGC1 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:911150f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9PTN2 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:91117924-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camphor targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9111a278-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camphor is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:9111caaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9111f2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:91121b0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:91124390-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01177 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:91126ba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:911293c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9112bbd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9112e566-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:91130f46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:911337e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:91135ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:472 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camylofin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:91138890-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9113b0c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9113d8ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:911401d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:91142a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBT6 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase kappa) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:911452c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNA4 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase iota) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:91147b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y253 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase eta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:9114a32e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9114ce9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9114f9f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:91152556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:91154f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:911577f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9115a030-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:9115c862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9115f0d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:91161916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canrenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:91164120-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capecitabine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:9116651a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:91168f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9116b862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9116e0a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:911708c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91173292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:91175aba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:911782ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9117ab32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9117d3c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9117fcfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q93T40 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase II) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:91182526-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:91184dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.85']} DrugCentral uuid:911877d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:9118a014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9118c83c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9118f082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:91191940-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9119417c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.94']} DrugCentral uuid:911969ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:91199244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9119ba8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9119e2c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:911a0b16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:911a3492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:911a5e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:911a86a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:911aaea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.577']} DrugCentral uuid:911ad758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:911aff62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:911b2780-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:911b4fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:911b7848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:911ba066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:911bc884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:911bf1b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:911c1b86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:911c43d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.74']} DrugCentral uuid:911c6be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:911c97f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:911c97f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:911ccfcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:911ccfcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:911d085c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:911d085c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:911d401a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:911d401a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:911d774c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:911d774c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:911dae74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:911dae74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:911df226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:911df226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:911df226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:911df226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:911df226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:911e46c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:911e6a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.495']} DrugCentral uuid:911e9348-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.125']} DrugCentral uuid:911ebb84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:911ee492-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:911f0d00-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:911f385c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:911f385c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:911f385c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:911f7376-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:911f7376-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:911fa6b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H461 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is allosteric modulator of GPCR (Frizzled-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:911fd06e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:911ff88c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:912020a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:91205c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91205c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91205c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91205c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91205c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91205c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91205c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9120b9d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone is inhibitor of Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9120e256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:91210a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51661 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:912133aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:91215bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:91218526-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9121ad80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9121d5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:9121fdbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9122277e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:91224fa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:912277ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:9122a014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.149']} DrugCentral uuid:9122c8a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa is inhibitor of Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:9122ec72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.168']} DrugCentral uuid:91231490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:91233cae-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:912366f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbimazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:91239168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbimazole is inhibitor of Enzyme (Thyroid peroxidase) DrugCentral uuid:9123b53a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbinoxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:9123d9a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carboprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:912401de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:912401de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:91244bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91244bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91244bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91244bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91244bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91244bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91244bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9124aa4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:510 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carubicin targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:9124ce34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9124f65c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:91251e7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6P7S1 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9125490e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13510 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9125712c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9125995e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmustine is inhibitor of Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9125c258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:9125e67a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:91260eb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:9126383c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:515 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:91266118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18910 biolink:molecularly_interacts_with DrugCentral:515 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:91268922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:9126ad08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfenazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:9126d0bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carpipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:9126f8e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carpipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:91272418-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:91274c36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:91277454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:91279cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9127c4fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9127ed26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:91281562-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carteolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:91283df8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carteolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:91286616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carumonam targets Enzyme (Peptidoglycan synthase FtsI) DrugCentral uuid:91288a92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is inhibitor of Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9128b346-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:9128dc9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:912904ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:91292d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:9129556c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9129815e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:9129abf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9129d6b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:9129fee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.273']} DrugCentral uuid:912a27ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.476']} DrugCentral uuid:912a5034-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:912a7866-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:912aa0a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:912aca14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:912af282-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:912b1ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:912b43ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:912b6c62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:912b9494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:912bbcc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:912be55c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.054']} DrugCentral uuid:912c0d8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:912c36d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:912c5f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:912c88a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.706']} DrugCentral uuid:912cb2ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:912cdaca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:912d02de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:912d2b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:912d561c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:912d7e62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:912da680-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:912dd042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:912df856-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefacetrile targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:912e1c3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:912e4004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:912e80dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912e80dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912e80dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912e80dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912e80dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912e80dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912e80dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912ee036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.14']} DrugCentral uuid:912f2014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912f2014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912f2014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912f2014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912f2014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912f2014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912f2014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912f7e1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.09']} DrugCentral uuid:912fbe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912fbe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912fbe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912fbe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912fbe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912fbe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:912fbe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91301bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:91305b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91305b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91305b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91305b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91305b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91305b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91305b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9130baa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54286 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Enzyme (Pencillin binding protein 2a; Penicillin binding protein 2'; Penicillin binding protein, PBP2; Penicillin-binding protein 2; Penicillin-binding protein 2'; Peptidase) DrugCentral uuid:9130df26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:913102ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:913141aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913141aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913141aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913141aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913141aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913141aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913141aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9131a082-dc5e-11ec-be2c-0242ac110005 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9131c896-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:9131ec54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q54906 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein) DrugCentral uuid:91322ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91322ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91322ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91322ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91322ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91322ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91322ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132a018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132a018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132a018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132a018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132a018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132a018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132a018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9132fe6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:91332240-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:9133469e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:91336fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9133aec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9133aec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9133aec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9133aec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9133aec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9133aec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9133aec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91340e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19174 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets Enzyme (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:91344d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91344d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91344d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91344d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91344d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91344d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91344d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9134abce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:9134e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9134e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9134e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9134e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9134e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9134e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9134e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9135452a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:91356d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:91359584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:9135bfa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:9135e476-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:91360ca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:91364c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91364c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91364c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91364c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91364c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91364c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91364c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9136aa0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:9136e718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9136e718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9136e718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9136e718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9136e718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9136e718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9136e718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913744ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:9137810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9137810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9137810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9137810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9137810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9137810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9137810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9137deca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:913806f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.512']} DrugCentral uuid:91382ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.659']} DrugCentral uuid:9138580a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:91388028-dc5e-11ec-be2c-0242ac110005 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9138a86e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.617']} DrugCentral uuid:9138d2b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9138fad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:91391e98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:913946ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:91396f88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:9139979c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9139d680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9139d680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9139d680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9139d680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9139d680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9139d680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9139d680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913a34a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:913a5858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:913a806c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:913abffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913abffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913abffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913abffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913abffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913abffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913abffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913b1f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:913b4632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) DrugCentral uuid:913b69e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:913b9204-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:913bba22-dc5e-11ec-be2c-0242ac110005 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:913be29a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:913c216a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c216a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c216a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c216a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c216a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c216a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c216a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913c9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913cf6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefprozil targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:913d1d7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:913d4784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.522']} DrugCentral uuid:913d6fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:913d982e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:913dc042-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:913de84c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:913e1056-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5A7N4 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Unclassified (tRNA 2'-phosphotransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:913e3900-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.261']} DrugCentral uuid:913e6114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.534']} DrugCentral uuid:913e8928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:913eb128-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q1J5W5 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein) DrugCentral uuid:913ed78e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60FU1 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:913f1686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913f1686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913f1686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913f1686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913f1686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913f1686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913f1686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913f7c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:913f9fe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime targets Enzyme (Beta-lactamase) DrugCentral uuid:913fda62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913fda62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913fda62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913fda62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913fda62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913fda62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:913fda62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914038c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.142']} DrugCentral uuid:914060f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.513']} DrugCentral uuid:91408930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.744']} DrugCentral uuid:9140b356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.213']} DrugCentral uuid:9140dd54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:91410572-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:91412930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:914151c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:914179e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9141b8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9141b8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9141b8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9141b8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9141b8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9141b8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9141b8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91422dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91422dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91422dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91422dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91422dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91422dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91422dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91429112-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9142bc32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9142e75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:914312d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.477']} DrugCentral uuid:91433b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9143634e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:91438b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.917']} DrugCentral uuid:9143b484-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9143dca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:914404ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.856']} DrugCentral uuid:91442cac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:91445538-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:91447d42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9144a556-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9144cd6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9144f5ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:91451e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:91454646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:91456ea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:914597c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:9145bfe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:9145e8ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9146110c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:91463b32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:91466364-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:91468b96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9146b3b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9146dc36-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:91470440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.627']} DrugCentral uuid:91472c68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.29']} DrugCentral uuid:914754b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:91477cea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9147a4f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9147cce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:9147f5f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:91481f74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:91484788-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:91486f92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HZR1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9148983c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9148c06e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9148e896-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:914910be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9149392c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:91496140-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:91498940-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9149b14a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9149da76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:914a03a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:914a2bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:914a5410-dc5e-11ec-be2c-0242ac110005 UniProtKB:O78750 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:914a7cf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:914aa528-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:914acddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:914af60e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:914b1e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:914b46cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:914b6eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:914b96f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:914bc2a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:914becda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:914c1520-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:914c3df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:914c6610-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:914c8e24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:914cb638-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:914cda64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16348 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin targets Transporter (Solute carrier family 15 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:914d193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d8fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d8fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d8fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d8fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d8fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d8fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914d8fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914deecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:914e1776-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:914e3b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:914e6370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:914e8b8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:914eb3f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:914edc7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35236 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:914f1b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914f1b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914f1b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914f1b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914f1b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914f1b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914f1b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:914f7a30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:914fa23a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:914fca4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:914ff302-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:91501b0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9150432a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:91506b20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9150937a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:9150bb66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9150e456-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:9151081e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:915132a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:91515dbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:915188b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9151b0ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9151d97e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:91520174-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:91522abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:91525322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:91527b4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9152a372-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9152e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9152e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9152e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9152e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9152e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9152e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9152e2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:915347be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:91536b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9153943a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9153d314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9153d314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9153d314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9153d314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9153d314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9153d314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9153d314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91543214-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:9154560e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:91547e2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:9154a668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9154cfee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00488 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Coagulation factor XIII A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9154fb40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:91552598-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceruletide is agonist of GPCR (Cholecystokinin receptor type A) DrugCentral uuid:91554974-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:91557232-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:91559a5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9155c278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrorelix targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:9155e654-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrorelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:91560eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:915636ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.983']} DrugCentral uuid:91565efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:915686f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.883']} DrugCentral uuid:9156b084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.201']} DrugCentral uuid:9156d99c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9157019c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.93']} DrugCentral uuid:915729a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:91575246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:91577a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13443 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Disintegrin and metalloproteinase domain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:9157a25a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9157ca5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62580 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Chloramphenicol acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9157f2be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:91581ac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q88N29 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Unclassified (Probable HTH-type transcriptional regulator TtgR) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:915843cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorcyclizine targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:91586c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:915895b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:9158bdd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9158e5fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:91590eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:915936ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:91595f14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:91598f02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:91598f02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:91598f02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:9159d64c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:9159d64c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:9159d64c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:915a1c74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:915a1c74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:915a1c74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:915a6472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:915a6472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:915a6472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:915aaa9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:915aaa9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:915aaa9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915b22e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:915c05a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:915c05a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:915c05a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:915c05a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:915c05a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:915c05a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:915c700a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:915c700a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:915ca728-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:915ca728-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:915cdc16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:915d042a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:915d2c48-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:915d55a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:915d7de2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:915da61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:915dce46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:915df754-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:915e1f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:915e4786-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:915e6fa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:915e981c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.764']} DrugCentral uuid:915ec044-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:915ee858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:915f1076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.163']} DrugCentral uuid:915f40c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:915f40c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:915f40c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:915f793a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:915f9d16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloropyramine targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:915fc688-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:915ff0a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:916018c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:91604176-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:91606a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:91609374-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9160bbb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9160e3ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:91610cbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:916134fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:91615d36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:91618572-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9161af3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9161d748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05227 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Cytosolic other (Histidine-rich protein PFHRP-II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9161ff70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9162278e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:91625024-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:91627856-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9162a0a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N6S8 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Cysteine proteinase falcipain 2a) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9162c8b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorothiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:9162ed0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9163150e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorotrianisene targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:916338f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorotrianisene is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:91635cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9163864c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9163aeb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9163d6d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:9163ff14-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:91642782-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:91644fa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.818']} DrugCentral uuid:916477be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:9164a130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9164c980-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:9164f1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:91651b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:91654482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9165759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9165759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9165759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9165b3e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:9165dcd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96JM7 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:916604f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05BQ5 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (MBT domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:91662d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:91665552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.842']} DrugCentral uuid:91667dd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:9166a606-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphentermine is substrate of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.471']} DrugCentral uuid:9166ce2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.404']} DrugCentral uuid:9166f64c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:91671f46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.987']} DrugCentral uuid:9167476e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:91676fbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.233']} DrugCentral uuid:916797d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9167c0ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9167e8e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:91681108-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:91683930-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:916862ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:91688afc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9168b324-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:9168db60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:916905ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:91692dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9169561c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:91697e58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9169a748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9169cf84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:9169f7b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:916a206a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:916a48a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:916a70e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:916a9928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.759']} DrugCentral uuid:916ac358-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:916aeb80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:916b13a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.746']} DrugCentral uuid:916b3bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.251']} DrugCentral uuid:916b647a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:916b8c98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:916bb4b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:916bdcb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:916c054c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:916c2d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:916c56d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:916c7efa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:916ca9de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:916cd4fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:916cfd3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:916d2562-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:916d4e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:916d7df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:916d7df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:916d7df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:916dbc66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:916de506-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:916e0d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:916e35b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:916e5de2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:916e8808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.061']} DrugCentral uuid:916eb030-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.713']} DrugCentral uuid:916ed84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.569']} DrugCentral uuid:916f0076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:916f28ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:916f510c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.043']} DrugCentral uuid:916f793e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:916fa1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.797']} DrugCentral uuid:916fc9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:916ff22e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:91701b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.835']} DrugCentral uuid:91704490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:91706df8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:91709634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.777']} DrugCentral uuid:9170be5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:9170e6de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:91710f38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:91713788-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:91715fd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9171886e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9171b0aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:9171d8e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9172010e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:91722b16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9172535c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:91727b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:9172a37a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9172e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9172e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9172e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9172e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9172e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9172e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9172e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:917364b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:917364b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:917364b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:917364b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:917364b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:917364b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:917364b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9173e014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9173e014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9173e014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9173e014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9173e014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:91743c8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91743c8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91747f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:91747f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:91747f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:91747f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:91747f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9174dd48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9174dd48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9174dd48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:917523e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:917523e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:917523e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:91757cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:9175f926-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:91762126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9176494e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04925 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Unclassified (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:917671da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:917699f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9176c61c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:9176c61c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:9176fa1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:91772260-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:91774a88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.367']} DrugCentral uuid:917772b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:91779cae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:9177c7a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9177f1a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:917819c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:91784244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:91786a4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:91789258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9178bb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:9178e668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.194']} DrugCentral uuid:91790eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:917936cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:91795f12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral uuid:917989a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9179b1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9179d9e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Surface antigen (Major prion protein) DrugCentral uuid:9179fdfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:917a2640-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.56']} DrugCentral uuid:917a4e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:917a7280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:917a9b34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:917ac370-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:917aeb98-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:917b13d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:917b3d28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:917b665e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:917b8e72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:917bb6ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:917bdf26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:917c0758-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:917c2f9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:917c57b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:917c8070-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:917caa14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29474 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, endothelial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:917cd23c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29476 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.554']} DrugCentral uuid:917cfa64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:917d2408-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is opener of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:917d4c08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:917d7444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:917d9c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:917dc50c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:917ded52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:917e157a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:917e3dac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:917e669c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.31']} DrugCentral uuid:917e8eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:917eb836-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:917ee0fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:917f0ba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:917f33ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:917f5caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:917f8540-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:917fad7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:917fd586-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.39']} DrugCentral uuid:917ffda4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:91802680-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:91804ea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:918076da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:91809fde-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9180c95a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:9180f1b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4QEW7 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:918119e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9181422c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:91816ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:918192cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9181baf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:9181debc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:9182077a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:91822fac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:918257e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:91828024-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9182aa90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:9182d2b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:9182faea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:918322fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:91834b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:918373a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:9183ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9183ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9183ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9183ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9183ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9183ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9183ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:91840dae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:918436c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:91845fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox is inhibitor of Unclassified (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:91848a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9184b25e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicloprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9184da7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicloprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9185036c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cidofovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:91852752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16444 biolink:molecularly_interacts_with DrugCentral:640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilastatin is inhibitor of Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:91854f98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22412 biolink:molecularly_interacts_with DrugCentral:640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilastatin targets Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:918577de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilazapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9185a060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9185cd06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9185cd06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9185faba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:918622e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:91864da8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:918677ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:9186a014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9186c85a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:9186f172-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:91871990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is inhibitor of Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:918741ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:91876a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:918792c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9187baf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9187e320-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet is allosteric modulator of GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:91880c4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinalukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:918837a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinalukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:91885b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:918883c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:9188ac9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:9188d4ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9188fd0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:9189255a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.552']} DrugCentral uuid:91894ddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.208']} DrugCentral uuid:9189762c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.987']} DrugCentral uuid:91899e86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:9189c82a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:9189f160-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:918a19a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.064']} DrugCentral uuid:918a41e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:918a6a28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:918a9304-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:918abb4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:918ae368-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:918b0c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:918b34b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:918b5cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.242']} DrugCentral uuid:918b8534-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.299']} DrugCentral uuid:918bad7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.793']} DrugCentral uuid:918bd8cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:918c00ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.97']} DrugCentral uuid:918c31b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:918c31b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:918c31b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:918c7098-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:918c9c94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:918c9c94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:918cca5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:918cf2c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:918d1af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q45066 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:918d432e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:918d6b74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:918d9496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:918dbcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918e1dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:918ef372-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:918ef372-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:918f26c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:918f4eda-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:918f77e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:918f9ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:918fc82e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:918ff056-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:9190191e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:91904132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:9190693c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:91909164-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9190b9f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:9190e218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:91910a2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:9191334e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:91915bb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.281']} DrugCentral uuid:919183d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9191ac7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.947']} DrugCentral uuid:9191d52e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:9191fd38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:91922646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.472']} DrugCentral uuid:91924e64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:919276e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.063']} DrugCentral uuid:91929f18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:9192c754-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9192ef68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:91931894-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:919340d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:919368f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:91939116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9193bb0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:9193e724-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9193e724-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:919429b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:919429b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:919429b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:919429b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:919429b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:919489fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:919489fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:919489fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:919489fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9194dc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9194dc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9194dc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9195235a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:9195235a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:9195235a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:919561d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:91959254-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:91959254-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:91959254-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9195d0d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:9195f906-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:919621a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.935']} DrugCentral uuid:919649d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:919671f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:91969a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.931']} DrugCentral uuid:9196c37c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9196eb9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.456']} DrugCentral uuid:919713ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:91973be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:919764a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:91978cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:9197b4e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9197dd02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:91980566-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:91982e06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:91985764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:91987f96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9198ab6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:9198d3a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9198fbc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q48255 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:919924a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15474 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:91994cf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPK8 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:91997504-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:919998e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.441']} DrugCentral uuid:9199c16c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9199e994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:919a11a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:668 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clarithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:919a39b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'MPC', 'has_quantitative_value': ['8.719']} DrugCentral uuid:919a634c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.187']} DrugCentral uuid:919a8e62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:919ab7ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:919adfac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:919b0856-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:919b307e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:919b589c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:919b80b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:919ba928-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:919bd146-dc5e-11ec-be2c-0242ac110005 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:919bf95a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:919c215a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:919c4c8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:919c7696-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:919c9eb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:919cc830-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:919cf062-dc5e-11ec-be2c-0242ac110005 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:919d1880-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:919d4094-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4TVR4 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:919d692a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:919d912a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:919db934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A3M1 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:919de15c-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:919e0ad8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:919e37ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:919e61ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:919e8a12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:919eb2ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:919edb16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:919f035c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:919f2b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:919f53fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:919f7c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:919fa474-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:919fd430-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:919fd430-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:919fd430-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:91a01fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:91a01fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:91a01fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:91a05e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:91a087c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:91a0affe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:91a0d84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:91a10076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:91a1290c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:91a15148-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.036']} DrugCentral uuid:91a17998-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:91a1a1de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:91a1cca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:91a1f4ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:91a21d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.604']} DrugCentral uuid:91a24558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:91a26e20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:91a2963e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:91a2be66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:91a2e6f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.084']} DrugCentral uuid:91a30f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.558']} DrugCentral uuid:91a33738-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:91a35f6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:91a388c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:91a3b140-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:91a3da76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:91a402bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:91a42c24-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:91a45442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:91a47d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:91a4a5aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:91a4ce36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:91a4f65e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91a51eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:91a546ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:91a571ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN4 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:91a59cb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:91a5c55c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:91a5ed70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:91a61642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:91a63e74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:91a666a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:91a68f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:91a6b782-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:91a6dfd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:674 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:91a703b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:674 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:91a7278a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:91a74db4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:91a775f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clindamycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:91a799c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:91a7c1f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:91a7ead0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:91a812f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:91a842c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:91a842c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:91a842c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:91a87ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05141 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 2) DrugCentral uuid:91a89f7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12235 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Transporter (ADP/ATP translocase 1) DrugCentral uuid:91a8c338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12236 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 3) DrugCentral uuid:91a8e700-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:91a90bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT1 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid is inhibitor of Transporter (Solute carrier family 17 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:91a933ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:91a95c30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:91a9814c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91a9aa28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91a9d246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:91a9f60e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HA47 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 1) DrugCentral uuid:91aa1a4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BZX2 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 2) DrugCentral uuid:91aa3e8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:91aa6698-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L2G3 biolink:molecularly_interacts_with DrugCentral:692 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofazimine targets Enzyme (Uncharacterized oxidoreductase CzcO-like) DrugCentral uuid:91aa8a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:692 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofazimine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:91aab29c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:91aadc04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:91ab06ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Enzyme (Lipoprotein lipase) DrugCentral uuid:91ab2c22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:91ab5440-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:91ab7cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clometacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:91aba512-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.461']} DrugCentral uuid:91abcd4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:91abf59e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:91ac1e2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.745']} DrugCentral uuid:91ac4666-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:91ac6fa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:91ac97c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:91acc1f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:91acea4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.062']} DrugCentral uuid:91ad129e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:91ad3af8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:91ad63d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:91ad8bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:91adb410-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:91addc2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:91ae04d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.889']} DrugCentral uuid:91ae2d14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.358']} DrugCentral uuid:91ae553c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:91ae7e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:91aea730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.371']} DrugCentral uuid:91aecf62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.668']} DrugCentral uuid:91aef79e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:91af207a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:91af49b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:91af71e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:91af9aaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.979']} DrugCentral uuid:91afc322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:91afeb54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.778']} DrugCentral uuid:91b0134a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:91b03b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:91b0652a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:91b08d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:91b0b5a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:91b0dda2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:91b10642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:91b12e74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:91b156ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:91b17eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.703']} DrugCentral uuid:91b1a7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:91b1d004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:91b1f854-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:91b2207c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:91b2498a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:91b271da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:91b29a0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:91b2c2a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.412']} DrugCentral uuid:91b2ead4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.007']} DrugCentral uuid:91b31306-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.696']} DrugCentral uuid:91b33b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:91b363f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:91b38c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:91b3b4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:91b3dcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:91b405e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.319']} DrugCentral uuid:91b42de0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:91b45720-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:91b47f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:91b4a7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:91b4d010-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Glutathione S-transferase P) DrugCentral uuid:91b4f40a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:91b51c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:91b5464e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:91b56e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.937']} DrugCentral uuid:91b59752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:91b5bf7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:91b5e9a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:91b611be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:91b639dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b693be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91b758ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:91b758ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:91b758ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:91b758ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:91b7abe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:91b7abe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:91b7abe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:91b7f402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:91b7f402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:91b7f402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:91b832b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P39051 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:91b85b40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:91b88b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:91b88b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:91b88b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9031a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:91b9eee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91b9eee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91b9eee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91b9eee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91b9eee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91b9eee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91ba87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:91bb5912-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:91bb83f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:91bbac14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:91bbd482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:91bbfd22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:91bc2536-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:91bc4d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:91bc759a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:91bc9e76-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:91bcc68a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:91bceea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:91bd16da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:91bd41dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:91bd6cb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:91bd9678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:91bdbfae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:91bde7c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:91be0fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:91be37fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:91be60c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:91be88da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:91beb1de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:91bed9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:91bf0bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:91bf0bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:91bf0bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:91bf4fae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70507 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:91bf7a56-dc5e-11ec-be2c-0242ac110005 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:91bfa2c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonixin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:91bfcaec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloperastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:91bff314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.524']} DrugCentral uuid:91c01b64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:91c0447c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:91c07474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:91c07474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:91c07474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:91c0ba4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:91c0ba4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:91c0ba4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:91c0fe12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:91c0fe12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:91c0fe12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:91c13d00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:91c13d00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:91c13d00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:91c17496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:91c19cdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:91c1c5fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:91c1ee30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:91c21702-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:91c24e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:91c24e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:91c24e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:91c24e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:91c24e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:91c2abb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:91c2abb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:91c2abb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:91c2ea4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:91c31292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.379']} DrugCentral uuid:91c33ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:91c36346-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.136']} DrugCentral uuid:91c38b6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:91c3b3aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:91c3dc36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:91c404fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.351']} DrugCentral uuid:91c42d12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:91c4554e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:91c47e48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:91c4a670-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:91c4ce8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.104']} DrugCentral uuid:91c4f6c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.995']} DrugCentral uuid:91c520a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:91c548fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:91c57136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:91c59990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.235']} DrugCentral uuid:91c5c21c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.429']} DrugCentral uuid:91c5eba2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:91c613e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.466']} DrugCentral uuid:91c63c24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:91c66564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:91c68daa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:91c6b5f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:91c6de36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:91c70726-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:91c72f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.267']} DrugCentral uuid:91c7579e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:91c77fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.106']} DrugCentral uuid:91c7a85c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:91c7d0ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:91c7f8c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:91c81c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:91c84884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.521']} DrugCentral uuid:91c8720a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:91c89a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.598']} DrugCentral uuid:91c8c318-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:91c8e78a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:91c90fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:91c938d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.712']} DrugCentral uuid:91c96160-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:91c98988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.645']} DrugCentral uuid:91c9b246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:91c9da5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:91ca03d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.159']} DrugCentral uuid:91ca2c12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:91ca543a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.058']} DrugCentral uuid:91ca7c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.089']} DrugCentral uuid:91caa552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:91cacd70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:91caf5ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.497']} DrugCentral uuid:91cb1de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:91cb467e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:91cb6ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:91cb96d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:91cbc004-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:91cbeb6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.471']} DrugCentral uuid:91cc16a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:91cc40d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.906']} DrugCentral uuid:91cc69b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:91cc91f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:91ccba18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.942']} DrugCentral uuid:91cce236-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:91cd0a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:91cd3394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:91cd5bd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:91cd83f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:91cdace8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.99']} DrugCentral uuid:91cdd51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:91cdfd42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:91ce2588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:91ce4e50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:91ce76aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPN5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Putative cytochrome P450 130) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:91ce9ed2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:91cec722-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:91cef076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:91cf18b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:91cf40bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:91cf6498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:91cf8eaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:91cfb6e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:91cfdf04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:91d00722-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:91d03f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:91d03f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:91d03f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:91d03f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:91d03f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:91d08a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxazolam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:91d0b30c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:91d0db3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.783']} DrugCentral uuid:91d10460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:91d12cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:91d1580c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.154']} DrugCentral uuid:91d1837c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:91d1acc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:91d1d4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:91d246f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:91d27462-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:91d29d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:91d2c584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:91d2edac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:91d315e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:91d341f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:91d36c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:91d39482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:91d3bd7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:91d3e5ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.594']} DrugCentral uuid:91d40de0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:91d435fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:91d45e76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:91d4868a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.181']} DrugCentral uuid:91d4ae8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:91d4d694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.591']} DrugCentral uuid:91d4ff70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:91d5277a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.792']} DrugCentral uuid:91d5511e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:91d57932-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:91d5a22c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:91d5ca54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:91d5f344-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:91d61b4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:91d643ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:91d66c0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:91d6943e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:91d6bc66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22310 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (UDP-glucuronosyltransferase 1-4) {'has_attribute_type': 'IAO:0000004', 'name': 'app Km', 'has_quantitative_value': ['4.208']} DrugCentral uuid:91d6e646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:91d70e6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:91d736aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:91d75ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.445']} DrugCentral uuid:91d788b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:91d7b0d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:91d7d902-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:91d80198-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:91d829ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:91d851fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:91d87a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:91d8a396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:91d8cbfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:91d8f40e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:91d91c22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:91d944e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:91d96e20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:91d99648-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:91d9be84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:91d9e706-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:91da0f38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:91da3756-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:91da5f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:91da885a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:91dab078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:91dad8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:91db00d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:91db297c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:91db51ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:91db79c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:91dba1f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:91dbca94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:91dbf3a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:91dc1bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:91dc44d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:91dc703e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:91dc9b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:91dcc75a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:91dcc75a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:91dd0a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91dd0a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91dd0a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91dd0a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91dd0a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:91dd6cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:91dd6cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:91dd6cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:91dd6cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:91ddbe80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:91ddbe80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:91ddbe80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:91de00c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:91de00c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:91de44fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:91de44fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:91de44fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:91de44fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:91de44fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:91dea142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:91dea142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:91dea142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91defac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:91df790a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:91df790a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:91df790a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:91dfb780-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:91dfdfc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:91e00abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:91e034bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:91e05cd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:91e080a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:91e0a974-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:91e0d188-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:91e0fadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:91e12322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:91e14bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:91e173ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:91e19c4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:91e1c584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:91e1ef78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:91e21778-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:91e23b2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:91e263d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:91e2879e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:91e2afc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:91e2d7ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:91e3005c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:91e32960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:91e3516a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:91e37d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:91e37d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:91e3bc7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:91e3bc7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:91e3bc7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:91e3fa98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27922 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:91e422ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GJT6 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:91e44b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:91e473ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:91e49c0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:91e4cff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:91e4cff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:91e4cff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:91e4cff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:91e51964-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:91e54178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.801']} DrugCentral uuid:91e56a18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:91e58fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.49']} DrugCentral uuid:91e5b7c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:91e5dfca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:91e60874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:91e63088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:91e659be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6B856 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin beta-2B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:91e681fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine is inhibitor of Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:91e6ab9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27957 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Unclassified (Tubulin polymerization-promoting protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:91e6d3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin beta-4B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:91e70378-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:91e70378-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:91e70378-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:91e7468a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:91e7468a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:91e779e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08828 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:91e7a9a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:91e7a9a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:91e7a9a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:91e7e874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:91e8107e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19754 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:91e838ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:91e8610a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:91e88a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:91e8b222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:91e8da5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:91e9029a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:91e92bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:91e94f84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:91e977c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:91e99fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:91e9c8ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:91e9f4ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:91e9f4ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:91ea2922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortivazol is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:91ea4d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cotinine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:91ea7166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:91ea998e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:91eac1c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:91eaeace-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:91eb1526-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:91eb3d3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:91eb6576-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:91eb8e02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:91ebb756-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:91ebdf92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:91ec07ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:91ec3096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:91ec58b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:91ec80c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:91eca8d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:91ecd30c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q33BM1 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G protein-coupled receptor GPR35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:91ecfbf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES90 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:91ed23fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:91ed4c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25815 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets Cytosolic other (Protein S100-P) DrugCentral uuid:91ed7014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:91ed983c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:91edc064-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:91ede8a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:91ee1262-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:91ee3aa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:91ee62c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.602']} DrugCentral uuid:91ee8aee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:91eeb56e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:91eedd96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:91ef05b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:91ef2e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:91ef562c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:91ef7e5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.235']} DrugCentral uuid:91efa69a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:91efcf76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:91eff7a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:91f01fee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.993']} DrugCentral uuid:91f048a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.353']} DrugCentral uuid:91f07232-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:91f09cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.385']} DrugCentral uuid:91f0c50c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:91f0ed2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.924']} DrugCentral uuid:91f115ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:91f13dc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:91f165de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.206']} DrugCentral uuid:91f18f14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:91f1b7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:91f1dbb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:91f204d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.728']} DrugCentral uuid:91f22cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:91f2580e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:91f28270-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.541']} DrugCentral uuid:91f2aab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.812']} DrugCentral uuid:91f2d2fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:91f2fb92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:91f323ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:91f34bec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.829']} DrugCentral uuid:91f374aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:91f39caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:91f3c4dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:91f3ecf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:91f41630-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:91f44060-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclofenil targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:91f46892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclofenil targets Nuclear other (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:91f490ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:91f4b946-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:91f4e182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:91f509aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:91f531be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:91f55a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:91f58330-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:91f5ab76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclopentolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:91f5cf2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclophosphamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:91f5f914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f62132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:91f64964-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f67178-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f69a40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:91f6c2cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f6eaea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WQA8 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Enzyme (Alanine racemase) DrugCentral uuid:91f70ea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:91f73734-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60391 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f7606a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WP31 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine is inhibitor of Enzyme (D-alanine--D-alanine ligase) DrugCentral uuid:91f78446-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WQA9 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine is inhibitor of Enzyme (Alanine racemase) DrugCentral uuid:91f7a80e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:91f7d298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:91f811d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f811d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f811d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f811d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f811d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f811d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f811d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:91f87d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:91f8a560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:91f8cd7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:91f8f600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:91f91e28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:91f9465a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is modulator of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:91f96f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:91f99902-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:91f9c436-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:91f9ef88-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:91fa18c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:91fa41ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02790 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:91fa69d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:91fa9208-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23284 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.01']} DrugCentral uuid:91faba30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:91fae2da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:91fb0b02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:91fb333e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08752 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:91fb5b84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:91fb85f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:91fbadfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:91fbd640-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHG7 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:91fbfe72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:91fcf610-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:91fd220c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:91fd4c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:91fd74fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:91fdabaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:91fdabaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:91fdabaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:91fdabaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:91fdf90c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:91fe21f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:91fe4b46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05412 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Transcription factor (Transcription factor AP-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:91fe74cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycrimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:91fe98d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:91fec166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:91fee9b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:91ff13aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.855']} DrugCentral uuid:91ff3d4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:91ff618e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:91ff8a10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:91ffb328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:91ffdb78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.419']} DrugCentral uuid:92000404-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.812']} DrugCentral uuid:92002c72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.652']} DrugCentral uuid:92005580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:92007dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9200a652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9200ceca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9200f8e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:92012154-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:920149e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:92017230-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.185']} DrugCentral uuid:92019b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9201c3a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9201ec2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92021672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:92024264-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.559']} DrugCentral uuid:92026abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:9202934a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:9202bce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9202e57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:92031590-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:92031590-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:92031590-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:92034ee8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:92037800-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:9203a05a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9203c918-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:9203f21c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:92041a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:9204426c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:92046a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:920493de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9204bc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9204e438-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:92050c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9205358c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92056cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:92056cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:92056cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:92056cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:92056cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9205d2bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9205d2bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9205d2bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9205d2bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9205d2bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:92062f14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:92062f14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:92062f14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9206767c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:9206767c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:9206767c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:9206b4ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9206dcac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:920705ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:92072e0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:92075628-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:92077f5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:9207a7d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.315']} DrugCentral uuid:9207d01c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9207f83a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:769 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cysteine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:92082076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15309 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (Prostatic acid phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'GI50', 'has_quantitative_value': ['7']} DrugCentral uuid:920849c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:920871ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (DNA polymerase beta) DrugCentral uuid:92089d44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:92089d44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:92089d44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:9208d6b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9208fece-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacarbazine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.255']} DrugCentral uuid:920926e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14181 biolink:molecularly_interacts_with DrugCentral:773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacarbazine targets Enzyme (DNA polymerase alpha subunit B) DrugCentral uuid:92094abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62993 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9209734a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:92099b86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60631 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9209c3b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96IV0 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Enzyme (Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9209ecb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:920a166a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:920a40c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:920a68f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:920a911c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:920ab9d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:920ae20c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:920b0a0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:920b3248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:920b67b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:920b67b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:920b67b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:920ba5fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:920bce42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28731 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Unclassified (Thrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:920bf804-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:920c202c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:920c4840-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.163']} DrugCentral uuid:920c716c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.087']} DrugCentral uuid:920c9a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:920cc270-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:920cebc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.976']} DrugCentral uuid:920d140a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:920d3ca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.425']} DrugCentral uuid:920d64dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.708']} DrugCentral uuid:920d8d22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:920db658-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:920ddf84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.265']} DrugCentral uuid:920e07a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:920e2fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:920e587e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:920e80c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:920ea4a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:920ec886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:920ef0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Enzyme (Steryl-sulfatase) DrugCentral uuid:920f14bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:920f3cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.053']} DrugCentral uuid:920f655c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:920f8f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:920fb7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.757']} DrugCentral uuid:920fe018-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15413 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 3) DrugCentral uuid:921003d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:92102db6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.929']} DrugCentral uuid:921058fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.762']} DrugCentral uuid:92108446-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:9210ac82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:9210d50e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:9210f8cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.279']} DrugCentral uuid:92112130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.388']} DrugCentral uuid:92114958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:92116e2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:92119656-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9211be7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:9211e69c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:92120f82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:921237be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone is inhibitor of Enzyme (Dihydropteroate synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:92125fbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:921287d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9212b054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:9212d57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:9212fd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:921325c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:92134ff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q57P83 biolink:molecularly_interacts_with DrugCentral:783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daptomycin targets Transporter (Outer membrane porin protein OmpD) DrugCentral uuid:921373ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:92139be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9213c408-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9213ecb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:921414da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:92143d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:92146516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92148ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:9214b6d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9214df1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:92150854-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:921530f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:92155944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:9215816c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9215aa7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9215d2ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:9215faa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Breakpoint cluster region protein) DrugCentral uuid:92161e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:92164700-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:92166f28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:92169750-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9216bf8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.07']} DrugCentral uuid:9216e8a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:921710cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:921738ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:92176112-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9217896c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9217b180-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9217d98a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:92180194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.33']} DrugCentral uuid:92182a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:92185234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:92187b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.46']} DrugCentral uuid:9218a3a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9218cfa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9218f7d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:92191ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9219482e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:921970ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:921998e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:9219c100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9219e982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:921a11b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:921a39be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:921a61e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:921a8b94-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:921ab3b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.77']} DrugCentral uuid:921adbe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:921b03f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:921b2c5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:921b548e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:921b7cb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:921ba4d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:921bcd38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:921bf556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:921c1e0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:921c460a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:921c70bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.03']} DrugCentral uuid:921c98e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:921cc134-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:921ce952-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:921d11e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:921d3a1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:921d6256-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:921d8a6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.35']} DrugCentral uuid:921db300-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:921ddb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.25']} DrugCentral uuid:921e0346-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:921e2b6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.16']} DrugCentral uuid:921e567a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.47']} DrugCentral uuid:921e7ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:921ea6c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:921ed118-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:921ef940-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:921f2168-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:921f4986-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:921f7212-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:921f9a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:921fc21c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06240 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase LCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.19']} DrugCentral uuid:921fea3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:922013de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:92203be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:92206500-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:92208d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:9220b5be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9220dddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:92210618-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:92212e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:922156d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:92217ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9221a708-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9221cf30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9221f866-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9222207a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:92224898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27037 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:922270ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:92229956-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9222c228-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9222ea64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:922312fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:92233b18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9223634a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:92238b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9223b46c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9223dc76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:92240480-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:92242ca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36894 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:92245606-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:92247e24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9224a642-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9224cf8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:9224f7fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:92252036-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9225485e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:92257086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:92259b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:9225c5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9225edfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:92261626-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:92263ec6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:922666da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.41']} DrugCentral uuid:92268ee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9226b702-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9226df7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:922707b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:92272fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:92275946-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9227836c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9227ab76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9227d380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9227fbe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:922823e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92284cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:92287510-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:92289d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9228c59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9228edce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9229160a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:92293f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:92296830-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:92299be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:92299be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:92299be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:92299be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9229e972-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9229e972-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:922a2068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:922a2068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:922a54f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01538 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Transcription factor (Myelin transcription factor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:922a7d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:922aa18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:922ac554-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:922ae908-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:922b0e24-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:922b31f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:922b59f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:922b81e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deanol targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:922baa5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deanol targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:922bd35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:788 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:922bf730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:788 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:922c1aee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:922c4366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:922c6b8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:922c9398-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:922cbfb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:922cbfb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:922d0530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:922d0530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:922d0530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:922d0530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:922d0530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:922d5094-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:922d7934-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:922d9d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferoxamine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:922dc52e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferoxamine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:922ded4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:922e15ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.84']} DrugCentral uuid:922e3e1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:922e6628-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GRG7 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:922e8e3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:922eb84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.97']} DrugCentral uuid:922ee314-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:922f0b3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:922f333c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:922f5bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:922f84c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:922fae3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:922fde86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:922fde86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:922fde86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92305686-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:92312976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demecarium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:92314d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:923170fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:92319578-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9231bee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denopamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:9231e712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:92320f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deptropine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:92323780-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deptropine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:923268ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:923268ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:923268ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9232a788-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deserpidine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:9232cb64-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:9232ef9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:92331380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:9233375c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:92335b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:9233840a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:9233840a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9233eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9234a786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:9234cff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.631']} DrugCentral uuid:9234f81c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:92352030-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:92354844-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.755']} DrugCentral uuid:923570d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.081']} DrugCentral uuid:923598da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.194']} DrugCentral uuid:9235c0f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:9235e934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9236130a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:92363b28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:92366350-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:92368718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9236af86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:9236d7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9237004e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:92372876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:923750e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:923778ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:9237a116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:9237ca2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:9237f03a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:92381844-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:92384062-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:92386970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9238921a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:9238ba42-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9238e26a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:92390ace-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:923932ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92398bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:923a53b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:923a53b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:923a53b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:923a91fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:923aba36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:923ae3c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b26c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:923b912c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:923bb954-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:923be172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:923c0986-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.025']} DrugCentral uuid:923c3226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:923c5a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:923c829e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:923caad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:923cd3b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.189']} DrugCentral uuid:923cfbe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:923d2424-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:923d4cc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:923d77d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:923d9fee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:923dc820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:923df0d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:923e18fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:923e411a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:923e6a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:923e92a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.027']} DrugCentral uuid:923ebab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28476 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-2) DrugCentral uuid:923ee61a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:923ee61a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:923ee61a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:923f5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:92401fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:924047f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:92407084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:924098a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:9240c188-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9240e9a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:92411386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:92413bcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:924163f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:924187bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9241b052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.932']} DrugCentral uuid:9241d87a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone targets Cytosolic other (Annexin A1) DrugCentral uuid:9241fc42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:924224a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:92424d28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.498']} DrugCentral uuid:92427550-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:92429d5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9242c58c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:9242eff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:92431834-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:9243405c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycorticosterone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) DrugCentral uuid:92436438-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycorticosterone pivalate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:92438ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:9243b4d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.88']} DrugCentral uuid:9243dcce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:9244008c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:924428f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:92445104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05112 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytokine (Interleukin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:92447990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9244a3ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9244cdc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.786']} DrugCentral uuid:9244f5e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:92451dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.517']} DrugCentral uuid:92454672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:92456e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:92459816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9245bbd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9245e460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:92460c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:924634a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:92465cc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:924685e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9246adf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:9246d5fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9246fe04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:92472686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:92474ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:924776c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:92479ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9247c730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9247ef3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:9248174e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:92483f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexbrompheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:9248655a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:92488e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9248c5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9248c5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9248c5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9248c5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9248c5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:92491ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:924942ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:92496b1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:924993a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:9249bbd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9249e416-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.607']} DrugCentral uuid:924a0c34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.384']} DrugCentral uuid:924a36c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:924a61de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:924a8bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.257']} DrugCentral uuid:924ab40e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:924addbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:924b05e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:924b2e02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:924b5616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:924b7e8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:924ba698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:924bceb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.898']} DrugCentral uuid:924bf8be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:924c21c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:924c49f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:924c7244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:924c9ac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:924cc2c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexloxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:924ceae4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:924d12ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:924d3b84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:924d63d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:924d8c06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:924db42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:924dde9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:924e0712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:924e36ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:924e36ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:924e36ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:924e7d14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:924e7d14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:924e7d14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:924ebb80-dc5e-11ec-be2c-0242ac110005 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:924ee394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:924f07f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:924f3010-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:924f5824-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:924f8f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:924f8f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:924f8f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:924f8f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:924f8f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:924feaf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:92501322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:92503b9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:925063fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:92508c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9250b44e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9250dce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9251052a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:92512d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.824']} DrugCentral uuid:9251557a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:92517f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9251a96c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9251d194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9251fa48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:925222b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:92525286-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:92525286-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:92525286-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9252949e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9252949e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9252c270-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:9252e638-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:92530f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:92533782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:925361ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:925385de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9253adfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:9253d1ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:9253faaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:92541e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.87']} DrugCentral uuid:925446a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:92546eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:92549726-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:9254bf4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9254e74e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:92550f58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92556b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:92562618-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is agonist of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'D2', 'has_quantitative_value': ['6.458']} DrugCentral uuid:92564e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:925676ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.48']} DrugCentral uuid:92569eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:9256c6ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is blocker of Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9256ef26-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:92571a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9257425a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:92578116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:92578116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:92578116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:92578116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:92578116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:92578116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:92578116-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:9257f3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9257f3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9257f3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:92583278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:92585bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:925883fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9258a7d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:9258ccba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9258f5b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:925922dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:925922dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:925967b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:925967b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:925967b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:925967b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:925967b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:925967b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:925967b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9259d272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dezocine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9259fa9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dezocine is antagonist of GPCR (Kappa-type opioid receptor) DrugCentral uuid:925a1ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42574 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (Caspase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:925a4720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55210 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (Caspase-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:925a6f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q17339 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Unclassified (Female germline-specific tumor suppressor gld-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:925a9734-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02083 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (N-acylethanolamine-hydrolyzing acid amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:925ac9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:925ac9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:925ac9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:925b0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:925b3036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:925b58a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is allosteric modulator of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:925b80cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:925ba976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:925bd266-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:925bfbec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:925c24b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:925c4cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:925c766c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.67']} DrugCentral uuid:925c9f52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:925cc770-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:925cefa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:925d184c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:925d4074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:925d704e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:925d704e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:925d704e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:925db6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:925db6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:925db6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:925dfe42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:925dfe42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:925dfe42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:925e4550-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:925e4550-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:925e4550-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:925e8bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:925e8bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:925e8bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:925ed2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:925ed2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:925ed2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:925f4b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:92602cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92602cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92602cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92602cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92602cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92602cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9260953a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:9260953a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:9260953a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:9260dd2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9260dd2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9260dd2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9261234c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9261234c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9261234c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92619714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92626bf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:92626bf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:92626bf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9262b2d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9262b2d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9262b2d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9262f942-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:9262f942-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:9262f942-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:92633fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:92633fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:92633fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:926385c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:926385c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:926385c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:9263cdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:9263cdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:9263cdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:926411b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.64']} DrugCentral uuid:92643dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:92643dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:92647182-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is activator of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:92649978-dc5e-11ec-be2c-0242ac110005 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibekacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.921']} DrugCentral uuid:9264c2a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9264e66c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:92651222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:92651222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:92651222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9265505c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:92657898-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.081']} DrugCentral uuid:9265a232-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15118 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3']} DrugCentral uuid:9265ccb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15119 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.699']} DrugCentral uuid:9265f4e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15120 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.097']} DrugCentral uuid:92661d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16654 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.301']} DrugCentral uuid:9266473c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:92666f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9266975a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9266bf78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9266e822-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9267105e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:92673868-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:92676072-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:926789b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:9267b1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:9267d9d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:9268027a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.577']} DrugCentral uuid:92682b42-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:92685450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:92687c78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9268a4f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:9268cd0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9268f536-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:92691d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:92694748-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:92697344-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:92699b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9269c3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:9269ec8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:926a14ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:926a3ca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:926a64f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:926a8d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:926ab588-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:926addba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:926b05d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:926b2fa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:926b57a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:926b7fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:926ba7ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:926bd08a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:926bf894-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:926c20b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:926c49e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:926c7274-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:926c9a9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:926cc2a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:926ceb8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:926d15a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:926d3db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:926d65da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:926d8e98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:926db6d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:926ddef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:926e0710-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:926e2f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:926e57c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60656 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:926e7fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAW8 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:926ea88c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:926ed2d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:926efd0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:926f251e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:926f4d28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:926f76ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:926f9eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:926fc2b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:926feabc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:9270137a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:92703c56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:92707374-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:92707374-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:92707374-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:92707374-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:92707374-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:9270c220-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:9270eb56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9271137e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.388']} DrugCentral uuid:92713bec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.354']} DrugCentral uuid:9271641e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:92718c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9271b48c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:9271dd54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:92720568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WMN1 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (ATP phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:92722d86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05982 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (NULLD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:927255c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:92728038-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:9272a98c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.773']} DrugCentral uuid:9272d1d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:9272f9fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.082']} DrugCentral uuid:92732286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:92734aae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:927372ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:92739b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:9273c420-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.079']} DrugCentral uuid:9273ed24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:92741574-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.033']} DrugCentral uuid:92743e6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.386']} DrugCentral uuid:927467d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.767']} DrugCentral uuid:92749170-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.327']} DrugCentral uuid:9274b9ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70676 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Unclassified (SMR1-alpha2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:9274e35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:92750b96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.61']} DrugCentral uuid:92753b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:92753b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:92753b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:92757a54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 didanosine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9275a2a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dienestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:9275cacc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dienogest is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:9275eeb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:927617d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:92763c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:92766400-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:92766400-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:92769182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:9276b5c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:9276d994-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:927701b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:927729f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.252']} DrugCentral uuid:927752c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:92777b10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:9277a450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:9277cca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:9277f5c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:92781e1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:92784644-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.439']} DrugCentral uuid:92786e6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:927896ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:9278bf34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:9278e766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.223']} DrugCentral uuid:92790f98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.272']} DrugCentral uuid:92793860-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:927960a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.437']} DrugCentral uuid:927988d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:9279b1a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.317']} DrugCentral uuid:9279dbe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.657']} DrugCentral uuid:927a0420-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:927a2c48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:927a5588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:927a7e1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:927aa632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:927ace64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.739']} DrugCentral uuid:927af74a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:927b1f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:927b47ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.593']} DrugCentral uuid:927b6fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:927b9a56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:927bc594-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:927befce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.983']} DrugCentral uuid:927c1800-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.847']} DrugCentral uuid:927c4064-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.361']} DrugCentral uuid:927c6882-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:927c9096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.483']} DrugCentral uuid:927cb8b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:927ce186-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:927d09ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:927d31ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:927d5a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:927d853c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:927dad50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:927dd564-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08580 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:927dfd6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 difenoxin is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:927e2208-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:927e4a44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:927e7262-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:927e9a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd1', 'has_quantitative_value': ['7.125']} DrugCentral uuid:927ec30c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:927eeb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:927f137a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:927f3c6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.648']} DrugCentral uuid:927f647e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:927f8e2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:927fb208-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:927fdada-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92801db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9280951a-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.783']} DrugCentral uuid:9280bd10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.136']} DrugCentral uuid:9280e538-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:92810dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:92813858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92817b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9281f1da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51450 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:928219f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.007']} DrugCentral uuid:92824220-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:92826b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.187']} DrugCentral uuid:9282932e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.526']} DrugCentral uuid:9282bb60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:9282e432-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:92830ec6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:928336ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.085']} DrugCentral uuid:92835f16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:92838784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.121']} DrugCentral uuid:9283afc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:9283d7e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:92840006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:928428a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.261']} DrugCentral uuid:928450ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.369']} DrugCentral uuid:928478e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:9284a0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9284cacc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.299']} DrugCentral uuid:9284f380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:92851b6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:92854394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydrocodeine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:92856798-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:92858fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.462']} DrugCentral uuid:9285b7d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9285e0e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.309']} DrugCentral uuid:928609be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.127']} DrugCentral uuid:928631e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:928659fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.385']} DrugCentral uuid:92868222-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.373']} DrugCentral uuid:9286ab62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:9286d394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:9286fbd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:928723ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:92874824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.442']} DrugCentral uuid:92877056-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:9287987e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.605']} DrugCentral uuid:9287c0a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:9287e518-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:92880d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.183']} DrugCentral uuid:92883536-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:928858f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:92888388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:9288ab92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.896']} DrugCentral uuid:9288d3ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:9288fbce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.79']} DrugCentral uuid:92892428-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:92894c3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9289746e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:92899d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.922']} DrugCentral uuid:9289c57c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.529']} DrugCentral uuid:9289ee6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:928a169e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:928a3ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.424']} DrugCentral uuid:928a6ca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.644']} DrugCentral uuid:928a9600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.364']} DrugCentral uuid:928abebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:928ae740-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.83']} DrugCentral uuid:928b0f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:928b3772-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:928b5b3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.752']} DrugCentral uuid:928b83f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:928bac20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:928bd452-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:928bfc7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.821']} DrugCentral uuid:928c254c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:928c4d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:928c710a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 5A) DrugCentral uuid:928c94d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:928cbd54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:928ce586-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.349']} DrugCentral uuid:928d0dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.416']} DrugCentral uuid:928d35d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:928d5e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:928d8694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:928daeb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:928dd6bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:928e024a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:928e2a5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:928e5272-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:928e82ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:928e82ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:928e82ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:928ec112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:928ee4da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:928f088e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:928f2d00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:928f50be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:928f747c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:928f983a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:928fc986-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:928fc986-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:928fc986-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9290090a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54699 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:929030f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:92905504-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:929078c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:92909c6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:9290c016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9290e82a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:929110ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:929138ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:92916142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:92918a50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9291b3c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9291dbea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:9292066a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.017']} DrugCentral uuid:92922eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9292571e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:92927f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9292a73c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:9292d004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9292f80e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:929327d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:929327d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:929327d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:92936f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:92936f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:92936f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9293b294-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9293dab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:92940320-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:92942b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimemorfan is inhibitor of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:92945370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.791']} DrugCentral uuid:92947b84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.312']} DrugCentral uuid:9294a42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:9294cc74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:9294f488-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:92951da0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.479']} DrugCentral uuid:929547a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:92956fee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:9295982a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:9295c052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.785']} DrugCentral uuid:9295e8de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:929610f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:9296391a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:92966142-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:929689f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:9296b200-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:9296da14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7KQK5 biolink:molecularly_interacts_with DrugCentral:902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetacrine targets Unclassified (Apical membrane antigen 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9297020a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:92972c62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:92975458-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:92977c94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9297a4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9297cd20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9297fce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9297fce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9297fce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:92983f94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:92983f94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:92986d0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:929894ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:9298bdfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9298e76e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:929911bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:929939c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:929961ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:92998a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9299b28e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9299daac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:929a02ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:929a2b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:929a53a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:929a7bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:929aa3e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:929acdd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:929af612-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:929b1e4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:929b4658-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:929b6ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:929b970c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:929bc006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:929be8a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:929c10b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:929c38ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:929c60f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:929c8a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:929cb362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:929cdb8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:929d0394-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:929d2c70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:929d5498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:929d7cc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:929da4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:929dcdce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:929df5f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:929e1df6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:929e461e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:929e6f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:929e9772-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:929ebf7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:929ee786-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:929f1062-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:929f386c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:929f609e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:929f8466-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:929fa87e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:929fd074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.018']} DrugCentral uuid:929ff87e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:92a0209c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:92a04aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:92a072b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:92a09bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:92a0c52e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:92a0ee14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:92a1163c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:92a13e64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:92a166be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:92a18ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.932']} DrugCentral uuid:92a1b736-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:92a1df4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:92a210be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:92a210be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:92a210be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:92a252c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:92a27aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.658']} DrugCentral uuid:92a2a3da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:918 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenoxylate is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:92a2cc02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:918 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenoxylate targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:92a2f420-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.076']} DrugCentral uuid:92a31c3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:92a344a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:92a36d38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:92a390f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:92a3b900-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:92a3dde0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:92a4025c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:92a4261a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:92a449d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:92a46e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:92a492f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:92a4bb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:92a4e370-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92a50bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:92a53492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.802']} DrugCentral uuid:92a55cc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:92a5850a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:92a5ae04-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:92a5d672-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:92a5fe9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:92a626b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.158']} DrugCentral uuid:92a65098-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:92a678c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:92a6a4b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:92a6a4b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:92a6dbbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:92a6dbbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:92a72248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92a72248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92a72248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92a72248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92a72248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92a72248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92a78ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:92a78ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:92a78ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:92a7cd9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:92a7f5b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TP1 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Protein prune homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:92a81e0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:92a84614-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:92a86e3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:92a89204-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:92a8ba54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:92a8e29a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:92a9066c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:92a92a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:92a94dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48544 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:92a9799e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:92a9a2d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.604']} DrugCentral uuid:92a9cb7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 distigmine is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:92a9ef6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:92aa17f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:92aa4004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Translocator protein) DrugCentral uuid:92aa63cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:92aa8be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:92aab476-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.735']} DrugCentral uuid:92aadc94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.156']} DrugCentral uuid:92ab04a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.658']} DrugCentral uuid:92ab2f50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.129']} DrugCentral uuid:92ab5b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:92ab8360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.434']} DrugCentral uuid:92ababa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:92abd41e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:92abfc46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.957']} DrugCentral uuid:92ac2464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:92ac4cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:92ac7586-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.862']} DrugCentral uuid:92ac9da4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05091 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram is inhibitor of Enzyme (Aldehyde dehydrogenase, mitochondrial) DrugCentral uuid:92acc16c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.319']} DrugCentral uuid:92ace96c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.738']} DrugCentral uuid:92ad13ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:92ad3cc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:92ad64f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:92ad8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.794']} DrugCentral uuid:92adb572-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.669']} DrugCentral uuid:92addda4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:92ae05d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.333']} DrugCentral uuid:92ae2e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:92ae56bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:92ae7ebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:92aea6e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:92aecf02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:92aef89c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:92af20c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:92af498c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:92af7326-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:92af9b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:92afc3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92afebd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:92b014de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:92b03d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:92b06538-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:92b08d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:92b0b628-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:92b0de50-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:92b10722-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:92b13062-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:92b15902-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:92b18134-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:92b1a95c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92b1d184-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:92b1faa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:92b222ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:92b24ab0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:92b272d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z2W7 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:92b29ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:92b2c3b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:92b2ebb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.976']} DrugCentral uuid:92b313fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:92b33c72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:92b36576-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:92b38e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:92b3b6d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:92b3df06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:92b4072e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:92b42f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:92b4588c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:92b480e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:92b4a918-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:92b4d154-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.256']} DrugCentral uuid:92b4f9b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:92b521ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:92b54a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:92b5723a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:92b59b02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.401']} DrugCentral uuid:92b5c316-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.301']} DrugCentral uuid:92b5eb48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:92b6137a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:92b63ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:92b664f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:92b68cec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.223']} DrugCentral uuid:92b6b500-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:92b6dd78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:92b70578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:92b72eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:92b757c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:92b7808e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:92b7a88e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:92b7cc6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:92b7f032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.086']} DrugCentral uuid:92b81b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:92b8456e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets GPCR (Growth hormone-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b88c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92b90d28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9603e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:92b9f184-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:92ba19ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide targets Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:92ba3d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:92ba659c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:92ba8e3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:92bab696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.988']} DrugCentral uuid:92baded2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:92bb06dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:92bb2c98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:92bb54c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:92bb7cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:92bba588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:92bbcdce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:92bbf5ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:92bc1e28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.013']} DrugCentral uuid:92bc472c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:92bc6f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:92bc9790-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:92bcbf9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:92bce7fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:92bd1026-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:92bd3858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:92bd608a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:92bd90dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:92bd90dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:92bd90dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:92bdc94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:92bdf162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:92be1a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:92be428e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:92be6aca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:92be92f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:92bebb88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:92bee3a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:92bf0bba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:92bf3400-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:92bf5dcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:92bf861c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.046']} DrugCentral uuid:92bfaed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:92bfd702-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:92bfff98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:92c027b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:92c04fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:92c077d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:92c0a042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:92c0c842-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:92c0f16e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:92c11996-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:92c143bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:92c16bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:92c193f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:92c1bd06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:92c1e5a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:92c20dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:92c235f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:92c25e6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:92c2868c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.19']} DrugCentral uuid:92c2aeb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:92c2d6f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:92c2ffcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.18']} DrugCentral uuid:92c327d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:92c34fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:92c37812-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:92c3a0d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:92c3c8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:92c3f0ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.375']} DrugCentral uuid:92c41902-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:92c4418e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:92c469ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:92c491ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92c4b9de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:92c4e332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:92c50b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:92c5336e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:92c55ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:92c58472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:92c5ac7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:92c5d580-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:92c5fe16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09172 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3']} DrugCentral uuid:92c6320a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:92c6320a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:92c6320a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:92c6320a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:92c6832c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:92c6832c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:92c6832c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:92c6c936-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:92c6c936-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:92c70b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:92c70b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:92c70b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:92c70b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:92c70b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:92c7683c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:92c7683c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:92c7683c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c7c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92c83802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:92c8602a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:92c88a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:92c8b3ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopexamine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:92c8d776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopexamine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:92c8fb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:92c92442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:92c94c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:92c974e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:92c99d1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:92c9c5be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:92c9eddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:92ca15fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:92ca3e22-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:92ca683e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:92ca905c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92cab884-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:92cae200-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:92cb0ad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:92cb32fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:92cb5b18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:92cb8336-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:92cbaba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:92cbd3d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:92cbfbfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:92cc2660-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:92cc514e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:92cc79f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:92cca220-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:92cccae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:92ccf31a-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:92cd1b56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:92cd4388-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:92cd6c14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:92cd9432-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:92cdbc50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:92cde48c-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:92ce0f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.066']} DrugCentral uuid:92ce3766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.337']} DrugCentral uuid:92ce5f7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.588']} DrugCentral uuid:92ce8798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.378']} DrugCentral uuid:92ceb060-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:92ced888-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:92cf0088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.744']} DrugCentral uuid:92cf28a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:92cf511e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:92cf7932-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:92cfa13c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:92cfc9dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.275']} DrugCentral uuid:92cff1fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:92d01b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:92d03eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:92d062ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:92d08b56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:92d0b392-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:92d0dce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:92d105c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:92d12e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:92d1563a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.631']} DrugCentral uuid:92d17e80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:92d1a7e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:92d1d2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:92d1fb3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:92d22358-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:92d24be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:92d27498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:92d29cb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.381']} DrugCentral uuid:92d2c4d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:92d2edb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:92d315ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:92d33d9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:92d36588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:92d38f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:92d3b7ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:92d3dfe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.53']} DrugCentral uuid:92d408e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:92d43170-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:92d45984-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:92d48184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:92d4a9a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:92d4d274-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 7) DrugCentral uuid:92d4f65a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.629']} DrugCentral uuid:92d51e78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:92d54696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.325']} DrugCentral uuid:92d570d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:92d598da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:92d5c0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:92d5e93e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:92d6115c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:92d6397a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:92d66198-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:92d68a42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:92d6b260-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:92d6dbd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:92d703e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:92d72cd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:92d754ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d7ae0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92d867c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:92d89008-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:957 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxercalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:92d8b3c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxifluridine targets Enzyme (Thymidylate synthase) DrugCentral uuid:92d8d798-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:92d9009c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:92d928b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.433']} DrugCentral uuid:92d950c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:92d974b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:92d99d86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:92d9c13a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:92d9e4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:92da08b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.914']} DrugCentral uuid:92da3156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.496']} DrugCentral uuid:92da5988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.288']} DrugCentral uuid:92da8192-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:92daa99c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:92dad264-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:92dafb72-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:92db2386-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92db4bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:92db75c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61823 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Ribonuclease pancreatic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:92db9dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.867']} DrugCentral uuid:92dbc5fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.805']} DrugCentral uuid:92dbee7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:92dc16f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:92dc3f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43870 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme HindIII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:92dc6728-dc5e-11ec-be2c-0242ac110005 UniProtKB:O52691 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme ScaI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:92dc8f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:92dcb80e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:92dce018-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:92dd082c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:92dd2bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:92dd54ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:92dd7cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:92dda50c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:92ddcd34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:92ddf58e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:92de1d98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09237 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Matrilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.14']} DrugCentral uuid:92de45d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxylamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:92de699c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drostanolone propionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:92de8f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:92deb780-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:92dedfb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.602']} DrugCentral uuid:92df08c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:92df31a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:92df59ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:92df8282-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.132']} DrugCentral uuid:92dfab22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:92dfd35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:92dffb86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.996']} DrugCentral uuid:92e023c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.027']} DrugCentral uuid:92e04d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:92e0758e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:92e09d8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:92e0c5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:92e0ee4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.076']} DrugCentral uuid:92e11674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.175']} DrugCentral uuid:92e13e9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:92e167dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:92e19068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:92e1b872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:92e1e82e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:92e1e82e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:92e1e82e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:92e22776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:92e24f8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:92e277bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:92e29fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drotaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:92e2c6ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drotaverine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:92e2eaa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e33184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:92e3a39e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:92e3cbf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:92e3f588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:92e41ed2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:92e44704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:92e46f22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:92e49830-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:92e4c076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92e4e89e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:92e510c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:92e5393e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.402']} DrugCentral uuid:92e5617a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:92e589b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:92e5b1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.352']} DrugCentral uuid:92e5db5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:92e6040e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.09']} DrugCentral uuid:92e62d80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:92e6567a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:92e67f4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:92e6a760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:92e6cf7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:92e6f7b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:92e7203c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dyclonine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:92e74850-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dyclonine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:92e76c36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dydrogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:92e7947c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dydrogesterone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.561']} DrugCentral uuid:92e7bf56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:92e7e328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:92e806f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:92e82f0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:92e857c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.506']} DrugCentral uuid:92e87fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:92e8a7e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:92e8d04e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:92e8f88a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:92e9209e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:92e9489e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:92e97206-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:92e99a9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.905']} DrugCentral uuid:92e9c2c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:92e9eaec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.472']} DrugCentral uuid:92ea138c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.384']} DrugCentral uuid:92ea3b8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.543']} DrugCentral uuid:92ea6486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:92ea8ca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.554']} DrugCentral uuid:92eab526-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:92eadd44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.937']} DrugCentral uuid:92eb056c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.615']} DrugCentral uuid:92eb2d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:92eb56fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.397']} DrugCentral uuid:92eb7fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.106']} DrugCentral uuid:92eba7ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:92ebd014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:92ebf8fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:92ec2280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.126']} DrugCentral uuid:92ec4a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.253']} DrugCentral uuid:92ec72b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:92ec9b3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:92ecc33e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.191']} DrugCentral uuid:92eceb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.633']} DrugCentral uuid:92ed1370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:92ed3e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:92ed66a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:92ed8ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:92edb758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92eddf80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:979 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebrotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:92ee0352-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 echothiophate is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:92ee2710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.131']} DrugCentral uuid:92ee4f92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.543']} DrugCentral uuid:92ee78a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:92eea0be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:92eec8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:92eef208-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.086']} DrugCentral uuid:92ef1a3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:92ef4276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:92ef6ad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:92ef9370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:92efbba2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:92efe3b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:92f00bde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:92f03492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:92f05cc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.202']} DrugCentral uuid:92f084ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:92f0ad0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.572']} DrugCentral uuid:92f0d668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:92f0fe90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:92f12730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:92f14f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:92f177c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.421']} DrugCentral uuid:92f19fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.529']} DrugCentral uuid:92f1c7f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:92f1f016-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.178']} DrugCentral uuid:92f219ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:92f241ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.006']} DrugCentral uuid:92f26adc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:92f29322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.485']} DrugCentral uuid:92f2bc6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.359']} DrugCentral uuid:92f2e4bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.463']} DrugCentral uuid:92f30d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:92f3312e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:92f35a50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:92f382c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.864']} DrugCentral uuid:92f3aadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:92f3d354-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:92f3fb5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.489']} DrugCentral uuid:92f42368-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:92f44b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:92f47552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:92f49d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.916']} DrugCentral uuid:92f4c584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:92f4edac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:92f516a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:92f53ed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:92f566ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:92f58f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:92f5b75a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:92f5df6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.999']} DrugCentral uuid:92f607a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.431']} DrugCentral uuid:92f62ff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.503']} DrugCentral uuid:92f659d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49146 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Neuropeptide Y receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.959']} DrugCentral uuid:92f682f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.498']} DrugCentral uuid:92f6ab1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:92f6d34c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:92f6fc46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:92f72482-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:92f74ca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:92f774b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92f79d40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:92f7c568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:92f7ed90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:92f81824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:92f84240-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:92f86a72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:92f89290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:92f8bb08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:92f8dee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:92f9070c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:92f92f3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:92f957e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Ceramide glucosyltransferase) DrugCentral uuid:92f97be2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:92f9a3f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XAY4 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Unclassified (Beta-lactamase VIM-1; Class B carbapenemase VIM-1; Metallo-beta-lactamase; Metallo-beta-lactamase VIM-1; Metallobeta-lactamase; VIM-1; VIM-1 metallo-beta lactamase; VIM-1 metallo-beta-lactamase; VIM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:92f9cc1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:J3SE37 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:92f9f4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:92fa1cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:92fa452c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:92fa6e4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edrophonium is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.79']} DrugCentral uuid:92fa96bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edrophonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:92fabf02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:92fae70c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:92fb0ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:92fb336a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:92fb5ba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:92fb83ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:92fbac6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:92fbd612-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11926 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:92fbfe30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09057 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine targets Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:92fc2676-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9TZZ6 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) DrugCentral uuid:92fc4a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:92fc732e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.621']} DrugCentral uuid:92fc9f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:92fc9f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:92fcccac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:92fcf556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:92fd1d9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:92fd45ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:92fd6dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:92fd9704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:92fdc0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:92fde9fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:92fe19ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:92fe19ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:92fe19ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92fe92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:92ff60d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emedastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:92ff8d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:92ffb764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:92ffdf96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:93000822-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:93003040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9300584a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75884 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets Enzyme (Putative hydrolase RBBP9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9300805e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emtricitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:9300a57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9300cd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9300f5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:93011dc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:930146ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:93016f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:9301971e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5EGZ1 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9301bf32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09470 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.94']} DrugCentral uuid:9301e7aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:93020b72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:9302305c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:93025410-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:930278b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:93029c68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 endralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:9302c044-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:9302e416-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:93030806-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:93032e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:93035216-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:930375e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:93039992-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q53I07 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide targets Viral envelope protein (Envelope glycoprotein) DrugCentral uuid:9303bdd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O40239 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide is inhibitor of Membrane other (Transmembrane glycoprotein gp41) DrugCentral uuid:9303e190-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76270 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide targets Unclassified (GP41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:93040968-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin targets Enzyme (DNA gyrase subunit A) DrugCentral uuid:93042d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21281 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin targets Enzyme (V-type proton ATPase subunit B, brain isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:93045954-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:93045954-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:93048abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:93048abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:9304b82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.345']} DrugCentral uuid:9304ee5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9304ee5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9304ee5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9304ee5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:93053b9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:930563a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:93058c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9305b452-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.03']} DrugCentral uuid:9305dc70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:93060038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:9306289c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:930650ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:930678ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:9306a0f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9306ca22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9306f218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:93071a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostacyclin receptor) DrugCentral uuid:93073dd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:93076784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93078fa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:9307b7d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9307dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9308086a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9308306a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9308587e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:93088114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:9308ac70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17394 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir targets Polyprotein (Protein P) DrugCentral uuid:9308d042-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir is inhibitor of Polyprotein (Protein P) DrugCentral uuid:9308f40a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:93091c14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9309448c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:93096c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:93099496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9309bcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9309e52c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:930a0d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:930a3554-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02928 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat is inhibitor of Enzyme (Cytochrome P450 4A11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:930a5d86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.678']} DrugCentral uuid:930a8842-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:930ab074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.859']} DrugCentral uuid:930ad892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:930b0128-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:930b293c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1024 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ephedrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:930b5182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:930b754a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:930b9db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:930bc162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:930be534-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:930c0906-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:930c312e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Histamine H2 receptor) DrugCentral uuid:930c5834-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:930c8250-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:930caa46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:930cd3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:930cfbae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.401']} DrugCentral uuid:930d2516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:930d4d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.26']} DrugCentral uuid:930d75de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:930d9e1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:930dc642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:930dee74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:930e17be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:930e4086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.449']} DrugCentral uuid:930e68c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:930e9126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:930eb9b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.484']} DrugCentral uuid:930ee1c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:930f09da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:930f31e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:930f5a5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:930f827a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:930faab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:930fd2de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:930ffd68-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:93102d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:93102d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:93102d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:93107338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:93107338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:93107338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9310b302-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9310db16-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.878']} DrugCentral uuid:93110348-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:93112bac-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:931153c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:93117bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9311a410-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9311cf08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9311f974-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9312219c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear other (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:931249e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:93127278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:93129aa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol targets GPCR (P2Y purinoceptor 12) DrugCentral uuid:9312bf80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9312e7c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:93131066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93133884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:93136084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:93138dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:93138dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9313cbdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9313cbdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9313cbdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:93140f8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:93140f8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:93144332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:93146b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:93149378-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:9314bba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.333']} DrugCentral uuid:9314e422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:93150ccc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.58']} DrugCentral uuid:93153508-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:93155d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:931586fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:9315af2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.714']} DrugCentral uuid:9315d760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9316000a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.367']} DrugCentral uuid:93162814-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:93165014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.889']} DrugCentral uuid:93167828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9316a0a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9316c8dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:9316f104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:93171922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.722']} DrugCentral uuid:9317430c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:93176d5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:93179582-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.099']} DrugCentral uuid:9317bd96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9317e744-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.354']} DrugCentral uuid:93180f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:931838ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:931860fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:931889a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9318b1ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:9318d5aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.754']} DrugCentral uuid:9318fdd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.836']} DrugCentral uuid:931926d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93194eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.064']} DrugCentral uuid:93197712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:93199f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9319c848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9319f07a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:931a1898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.487']} DrugCentral uuid:931a4106-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:931a6938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:931a9200-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:931aba28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:931ae35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:931b0bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:931b33e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:931b5bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.041']} DrugCentral uuid:931b849e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:931bac9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.11']} DrugCentral uuid:931bd4a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:931bfdb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:931c264c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:931c4e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:931c7688-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:931c9ee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08786 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Cholecystokinin A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:931cc8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O32393 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Unclassified (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:931cf11c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:931d1962-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:931d4194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:931d6a66-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:1044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eritoran targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:931d9298-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:931dbaac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:931de2ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:931e0b60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:931e34aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:931e5cbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:931e84e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:931eaf7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:931ed7ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:931effb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:931f2892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:931f50b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:931f78c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:931fa0d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:931fc950-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:931ff286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:93201ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:932042ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93206c02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93209420-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9320bc48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9320e452-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:93210d88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:93213592-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:93215db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:932185c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9321aeaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9321d6b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9321fec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:932226d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9322512a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:93227952-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9322a170-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9322c984-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9322f1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:93231a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:93234256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:93236b28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:93239350-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9323bb5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9323e490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93240e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:932436a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:93245eb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:932486de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9324af4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9324d760-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9324ff7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9325279c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:9325505a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:93257882-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9325a082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9325c8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9325f316-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:93261d32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:93264546-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93266d82-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:932695e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9326be2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9326e64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:93270e5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:93273708-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:93275f12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9327871c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9327b016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9327dd0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:93280598-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:93282da2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:93285624-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:93287e56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9328a674-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9328ce9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9328f78c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:93291fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:932947e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:93296ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:93299944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9329c158-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:9329e976-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:932a12ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:932a3b4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:932a6360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:932a8b74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:932ab39c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:932adc6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:932b0482-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:932b2c96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:932b54a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:932b7f66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:932ba784-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:932bd0ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:932bf95a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:932c2182-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:932c498c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:932c71be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:932c9a68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:932cc29a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:932ceab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:932d12ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:932d3bb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:932d63e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:932d8c0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94956 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib is inhibitor of Transporter (Solute carrier organic anion transporter family member 2B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:932db524-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:932ddd88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:932e0150-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:932e250e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:932e496c-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:932e6dc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:932e919c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:932eb578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:932ed94a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1B) DrugCentral uuid:932efcfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:932f27d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:932f4fd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:932f77d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:932fa06e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:932fc95e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:932ff29e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:93301ac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9330460e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:93306e5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:93309686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.412']} DrugCentral uuid:9330becc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.706']} DrugCentral uuid:9330e7e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:9331100c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9331383e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:93316066-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:933188f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9331b0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9331d906-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9332050c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:9332050c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:93323af4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:93323af4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:93323af4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:933279b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:933279b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:933279b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:9332ba7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:9332ba7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:9332ba7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:9332f9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:9332f9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:9332f9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:93333292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:93335b14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.538']} DrugCentral uuid:93338332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.725']} DrugCentral uuid:9333ab50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.926']} DrugCentral uuid:9333d3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9333fc54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:93342490-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol is activator of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93344c9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:933474ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:93349e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9334c85a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:9334f064-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.83']} DrugCentral uuid:93351896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:93354104-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:9335690e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:93359118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.947']} DrugCentral uuid:9335b9e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:9335e212-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:93360a30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:93363226-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08537 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:93365b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19785 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:933685b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9336b192-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:9336b192-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:9336e5c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:93370e4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.767']} DrugCentral uuid:93373680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:93375ea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.637']} DrugCentral uuid:933786c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.446']} DrugCentral uuid:9337afa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:9337d7fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9338002e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:933828ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:93385312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.156']} DrugCentral uuid:93387b30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.902']} DrugCentral uuid:9338a36c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol cypionate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:9338c7b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol mustard targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9338efe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol valerate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:933913ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:93393796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:93395fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9339887c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:9339b0a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9339d8ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:933a01d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:933a2aa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:933a5284-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:933a7c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:933aa48c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:933acd9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:933af5cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:933b1dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:933b470c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:933b6f34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:933b9766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:933bc74a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:933bc74a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:933bc74a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:933c0976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:933c0976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:933c0976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:933c4850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:933c4850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:933c4850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:933c877a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:933c877a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:933c877a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:933cc64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:933cc64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:933cc64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:933d051a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:933d051a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:933d051a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:933d3cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid is inhibitor of Transporter (Solute carrier family 12 member 1) DrugCentral uuid:933d6096-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:933d88a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08263 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:933db320-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.939']} DrugCentral uuid:933ddca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:933e04c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:933e2cec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:933e556e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:933e7d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:933ea5a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:933ecdb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WNL8 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:933ef924-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WNL6 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase B) DrugCentral uuid:933f1d3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WNL5 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase C) DrugCentral uuid:933f40f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:933f6918-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WNL9 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol is inhibitor of Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:933f8ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:933fb256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:933fd60a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-2) DrugCentral uuid:93400166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:93400166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:93400166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:9340413a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9340413a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9340413a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9340783a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:9340a076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9340c916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.964']} DrugCentral uuid:9340f13e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:93411966-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:93414184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:93416a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:9341935a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9341bc40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.353']} DrugCentral uuid:9341e472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:93420ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.985']} DrugCentral uuid:934234fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.83']} DrugCentral uuid:93425d26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:93428562-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9342ae3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:9342d65c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9342fe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.246']} DrugCentral uuid:93432760-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:93435136-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:93437940-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9343a154-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:9343c9cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide targets Enzyme (Catalase-peroxidase) DrugCentral uuid:9343eda8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) DrugCentral uuid:9344115c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:93443a92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:9344631e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.78']} DrugCentral uuid:93448b46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:9344b35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.111']} DrugCentral uuid:9344db82-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:934504e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:93452b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:9345510c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:93457920-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9345a2ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:9345cb78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:9345f3be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:93461bdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:93464468-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:93466c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethosuximide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9346b268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:93472f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:9347575e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:93478058-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9347a88a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:9347d0bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9347f8e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:9348217a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:934849b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:934871c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:934899f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9348c2c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9348eb0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:93491422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:93493d6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:93496620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:93498e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9349b6c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9349df56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:934a0788-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:934a2f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:934a57c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:934a814a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:934aaba2-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:934ad3ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:934afc60-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:934b2514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:934b4d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:934b756e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:934ba188-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:934ba188-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:934bd554-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:934bfd68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:934c2590-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:934c4e62-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:934c78ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:1091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl biscoumacetate targets Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:934c9d7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:934cc5a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:934cee6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.983']} DrugCentral uuid:934d17e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:934d4042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:934d6414-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:934d8caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.889']} DrugCentral uuid:934db4e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:934ddd04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:934e054a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:934e2a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:934e5086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.368']} DrugCentral uuid:934e789a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:934ea0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:934ec9a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:934eee88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:934f126e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:934f3636-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:934f5ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:934f86b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:934faecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:1098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:934fd6f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:934fffda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilefrine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:93502bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:93502bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:93502bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:93507186-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:93507186-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:93507186-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:9350b100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:9350b100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:9350b100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:9350f0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:9350f0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:9350f0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:93512838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etodolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:935150ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etodolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.577']} DrugCentral uuid:935178d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:9351a100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9351c8f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9351f4d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:93521e96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:93524e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:93524e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:93524e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:935294d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:935294d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:935294d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9352d2a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:9352f654-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:93531a6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:93534276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:93536bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.051']} DrugCentral uuid:935393de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:9353bddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:9353e604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.282']} DrugCentral uuid:93540f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.21']} DrugCentral uuid:93543730-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:93545bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:935483d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:9354a792-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:9354cb5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:9354ef72-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:9355133a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:93553b4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:93556376-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93558c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9355b470-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:9355dca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:935604b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:93562d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9356560a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:93567e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9356a63c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9356cebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9356f6f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:93571ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:93574704-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:93576d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9357952e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9357bd4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9357e5ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1116 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:93580ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:1116 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) DrugCentral uuid:93582e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.63']} DrugCentral uuid:9358568a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:93587e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9358a6f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9358caca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9358f2f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93591b10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exemestane targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:935940fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exemestane is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:9359693a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:1123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:93599162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:1123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exenatide targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:9359b980-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHC9 biolink:molecularly_interacts_with DrugCentral:1125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ezetimibe is antagonist of Membrane other (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9359e23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6T3U3 biolink:molecularly_interacts_with DrugCentral:1125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ezetimibe targets Unclassified (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:935a0a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:935a328e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:935a5b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:935a832e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:935aab4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:935aceec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:1128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famciclovir targets Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:935af34a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.93']} DrugCentral uuid:935b1dac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:935b45ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:935b6dfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:935b969c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:935bbf46-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:935be76e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:935c1086-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:935c3944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:935c616c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:935c89a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:935cb1c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:935cdc00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:935d046e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:935d2c82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:935d54a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:935d7d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.304']} DrugCentral uuid:935da536-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:935dcd4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:1130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famprofazone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:935df57c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:935e1e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:935e468a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:935e6e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:935e96a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:935ec132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13500 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Cytokine (C-C motif chemokine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:935ee93c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:935f127c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:935f3ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62868 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:935f62d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:935f8b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:935fb31c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:935fdbda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:936004d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:93602cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:936054de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:93607a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:9360a3b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:9360c784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.049']} DrugCentral uuid:9360ef70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:93611838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:93614060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:93616432-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:9361880e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.339']} DrugCentral uuid:9361b0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.168']} DrugCentral uuid:9361d8f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:93620112-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is activator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:936230e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:936230e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:936230e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:93626fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:936297c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9362bfd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:9362e3f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:936307ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:93632fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:936357f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:936380be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9363a8e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35384 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:9363d1cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.004']} DrugCentral uuid:9363f9ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:9364235c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.428']} DrugCentral uuid:93644b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:936473ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.172']} DrugCentral uuid:93649bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:9364c564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:9364ed8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:936515d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:93653df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:936566ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:93658ed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:9365b6f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:9365def4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.726']} DrugCentral uuid:93660988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.489']} DrugCentral uuid:936633b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:93665bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:936683ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:9366ac62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.735']} DrugCentral uuid:9366d480-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:9366fc9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:936724a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:93674d7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:936775a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:93679dc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.331']} DrugCentral uuid:9367c854-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.032']} DrugCentral uuid:9367f388-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.164']} DrugCentral uuid:93681ba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:936843e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.808']} DrugCentral uuid:93686c78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:936894aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9368bcaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9368e4c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:93690d9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:936935ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:93695dd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:93698608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9369b088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9369d8c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:936a00ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:936a290a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:936a5934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:936a5934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:936a5934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:936a98c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:936ac0ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:936ae98a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:936b11a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:936b39a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:936b6572-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:936b6572-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:936b9dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:936bc7ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:936beff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:936c186e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.001']} DrugCentral uuid:936c4082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:936c6882-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:936c9096-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:936cb94a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:936ce17c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:936d0990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:936d31ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:936d5a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:936d8280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:936dab16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:936dd348-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:936dfbd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:936e23e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:936e5778-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:936e5778-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:936e5778-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:936e5778-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:936ea58e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:936ea58e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:936ed8d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:936f00f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:936f2a9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:936f52c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentiazac targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:936f7acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:936fa2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:936fcb94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:936ff4f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:93701d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:9370454c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:93706e1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14060 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:93709646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24008 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:9370be5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:9370ea60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9370ea60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:93711e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:93714690-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:93716ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.704']} DrugCentral uuid:9371a2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:9371a2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:9371a2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:9371a2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:9371e76c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:9371e76c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:937218ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:937218ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:93724720-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:93726f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:93729720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:9372c0c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:9372ec20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.77']} DrugCentral uuid:93731650-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:93733e96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9373670e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:93738fa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fleroxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:9373b7cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:9373dfea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:93740880-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flopropione is inhibitor of Enzyme (Catechol O-methyltransferase) DrugCentral uuid:93742c3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:93745006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:93747824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:9374a1fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxuridine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:9374c888-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxuridine targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9374f2b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:93751acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:93754466-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:93756c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9375947a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9375bca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9375e51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:93760d1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9376352e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:93765d4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:937687b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9376b0da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0CS13 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:9376d4b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12461 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:9376f87e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02829 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine targets Cytosolic other (ATP-dependent molecular chaperone HSP82) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:93772100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:93774928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:93777132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:93779946-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9377c1d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9377e9fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:93781240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:93783a68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:9378618c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9378898c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:9378ad68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:9378d586-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:9378febc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:937926c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:93794f02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9379775c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:93799f84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9379c784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9379ef98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:937a18a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:937a40f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:937a68f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:937a91fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:937abaae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:937ae3ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:937b0c0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:937b3420-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:937b5c8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZQ8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:937b84b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:937bad06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:937bd51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:937bfe0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:937c2600-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:937c4e32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is agonist of GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.863']} DrugCentral uuid:937c7628-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:937c9edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:937cc704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:937cef2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:937d174a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:937d4012-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:937d6ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:937d6ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:937d6ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:937db5f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:937db5f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:937db5f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:937dfeda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:937dfeda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:937dfeda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:937e4520-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:937e4520-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:937e4520-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937ebd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:937fa1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:937fa1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:937fa1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:937fa1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:937fa1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:937fa1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:93800a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:93800a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:93800a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:938050ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:938050ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:938050ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:938096ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:938096ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:938096ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9380dd6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:9380dd6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:9380dd6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9381544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:93822866-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumetasone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:93824c42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:93827488-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:93829cba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:9382c564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:9382ed96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:938315c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:93833ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.304']} DrugCentral uuid:93836744-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:93838f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:9383b79e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:9383e05c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:93840898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:938430de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:9384591a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:9384819c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:9384aac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9384d304-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.151']} DrugCentral uuid:9384fb2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:93852462-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.103']} DrugCentral uuid:93854c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:938574d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:93859d0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9385c64c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:9385ee92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:938616ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.357']} DrugCentral uuid:93863f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:93866778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:93868faa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:9386b7c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:9386e00e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:93870ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:938732f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:93875b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:938783e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9387b4b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9387b4b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9387b4b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9387f32c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:93881b2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:938843a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93886cbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:93889502-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9388be38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9388e71e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunisolide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:93890f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunisolide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:93893782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:93896068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:938988b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9389b108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9389e0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9389e0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9389e0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:938a2764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:938a2764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:938a2764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:938a6d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:938a6d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:938a6d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:938ab6de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:938ab6de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:938ab6de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:938b00c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:938b00c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:938b00c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:938b4874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:938b4874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:938b4874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938bc024-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:938c9896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:938c9896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:938c9896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:938cdeaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:938cdeaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:938cdeaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:938d2676-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:938d2676-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:938d2676-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:938d6c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:938d6c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:938d6c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:938db2c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:938db2c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:938db2c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:938df146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1204 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:938e1978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1204 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.475']} DrugCentral uuid:938e4326-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1205 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.622']} DrugCentral uuid:938e6d88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1205 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.538']} DrugCentral uuid:938e95c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.042']} DrugCentral uuid:938ebdd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:938ee696-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:938f0ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:938f36fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.801']} DrugCentral uuid:938f5f18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.067']} DrugCentral uuid:938f88b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:938fb0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:938fd8e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9390012a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:93902ad8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:9390530a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.091']} DrugCentral uuid:93907b32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9390a346-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:9390cc18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9390f42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:93911c40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:93914454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:93916ccc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:939194ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:9391bd30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:9391e648-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.047']} DrugCentral uuid:9392106e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:9392388c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:939260b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:9392895e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:9392b17c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.444']} DrugCentral uuid:9392d9a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:9393019a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:93932a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:93935294-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:93937ac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9393a2e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9393cd32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9393f726-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:9394203e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:93944870-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:93947156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:93949974-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9394c1a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9394f5ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9394f5ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9394f5ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9394f5ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9395482e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9395482e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9395482e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:93958f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:93958f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:93958f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9395cfa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:9395f7c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25122 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:93961ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:939648c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxymesterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:939670fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:93969936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9396c154-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:9396e9ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:939711cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.058']} DrugCentral uuid:93973a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:93975ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:93978832-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9397b046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.066']} DrugCentral uuid:9397d86e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:93980136-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:93982954-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9398517c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:939879a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9398b14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9398b14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9398b14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9398b14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9398b14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9399061c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.075']} DrugCentral uuid:93992e4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.649']} DrugCentral uuid:9399591e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.269']} DrugCentral uuid:939984c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:9399ad24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.067']} DrugCentral uuid:9399d60a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9399fe3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:939a2664-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:939a4fe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.838']} DrugCentral uuid:939a7858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.044']} DrugCentral uuid:939aa080-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:939ac8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:939af1de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.464']} DrugCentral uuid:939b1b1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:939b433c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.191']} DrugCentral uuid:939b6b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:939b9378-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:939bbc22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:939be436-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.793']} DrugCentral uuid:939c0c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:939c345e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:939c5d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.575']} DrugCentral uuid:939c8558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:939cad94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.315']} DrugCentral uuid:939cd5d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:939d000a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.655']} DrugCentral uuid:939d2828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:939d5050-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:939d78e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:939da168-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.788']} DrugCentral uuid:939dc97c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:939df1ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.535']} DrugCentral uuid:939e1a9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.019']} DrugCentral uuid:939e42da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:939e6af8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.005']} DrugCentral uuid:939e932a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:939ebca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:939ee6d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:939f0f12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.397']} DrugCentral uuid:939f3744-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:939f5fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:939f87ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.708']} DrugCentral uuid:939faff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.125']} DrugCentral uuid:939fd82a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93a000d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.67']} DrugCentral uuid:93a02ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:93a052dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.061']} DrugCentral uuid:93a07b0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:93a0a4a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:93a0ccda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:93a0f4da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:93a11cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:93a1458e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:93a16dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:93a19db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:93a19db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:93a19db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a1f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:93a26ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine decanoate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:93a2929a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:93a2bae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:93a2e308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:93a30b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:93a33394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:93a35bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:93a3840c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.048']} DrugCentral uuid:93a3ac84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:93a3d4ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:93a3fcd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:93a424de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:93a44e50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:93a47682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:93a49eaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:93a4c6c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:93a4f062-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.961']} DrugCentral uuid:93a51894-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.145']} DrugCentral uuid:93a540a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.841']} DrugCentral uuid:93a56916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:93a59152-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:93a5b970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:93a5e288-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:93a60bfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:93a6365c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:93a65e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:93a686a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:93a6af42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:93a6d774-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:93a6ff74-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 3) DrugCentral uuid:93a7235a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:93a74be6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1216 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:93a7704e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludroxycortide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.695']} DrugCentral uuid:93a79880-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludroxycortide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:93a7c094-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.222']} DrugCentral uuid:93a7f280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:93a7f280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:93a7f280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:93a83498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:93a85cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:93a885a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:93a8adc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:93a8d5d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:93a8fe28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:93a92696-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93a94ea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:93a976d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93a99fd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:93a9ca9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:93a9f2f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.436']} DrugCentral uuid:93aa1b1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:93aa4364-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93aa6c22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:93aa959e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:93aabdda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:93aae620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:93ab0e8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:93ab36ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:93ab5efc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:93ab87e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:93abb00a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:93abd828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:93ac0046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:93ac2904-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93ac512c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93ac794a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93aca168-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:93acc9ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.082']} DrugCentral uuid:93acf23a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:93ad1a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:93ad4276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:93ad6c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:93ad9870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.74']} DrugCentral uuid:93adc21e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:93adeac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.77']} DrugCentral uuid:93ae1368-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate targets Enzyme (Cytosolic phospholipase A2) DrugCentral uuid:93ae3744-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.12']} DrugCentral uuid:93ae5f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:93ae8780-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:93aeafee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:93aed3ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:93aefbde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:93af2406-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:93af4f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:93af778a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:93af9fda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:93afc7e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:93aff0b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:93b018d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:93b0411a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:93b06ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:93b09304-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:93b0bb0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:93b0e322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 folic acid targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:93b10bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 folic acid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:93b1341c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucovorin targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.071']} DrugCentral uuid:93b15c44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucovorin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:93b18d18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:93b18d18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:93b18d18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:93b1c8c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:93b1c8c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:93b1fc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fondaparinux is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:93b2243a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formestane targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:93b24cc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:93b274f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:93b29d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:93b2c548-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:93b2eed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:93b316e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:93b33eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:93b36796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosamprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:93b38c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosamprenavir is inhibitor of Enzyme (Pol polyprotein) DrugCentral uuid:93b3b002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet is inhibitor of Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:93b3d816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08546 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93b40016-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:93b42884-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93b4508e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfluconazole targets Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:93b4744c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q836E5 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1) DrugCentral uuid:93b4980a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q831A8 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2) DrugCentral uuid:93b4bcc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A749 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin is inhibitor of Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:93b4e4cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HVW7 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:93b50ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:93b534ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:93b55e70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosphenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:93b5824c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:93b5aa7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:93b5d2e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:93b5fce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fructose targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:93b624fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ftivazide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:93b64d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:93b67558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:93b69e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:93b6c65c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:93b6ee7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:93b716a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:93b73ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93b766fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93b78efc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:93b7b710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:93b7dfc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:93b807ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furaltadone targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:93b82fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:93b858e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:93b87f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:93b8a756-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:93b8cf60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:93b8f7e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:93b92000-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:93b9492c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93b97140-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:93b999fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:93b9c244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:93b9ea62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:93ba128a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:93ba3b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93ba638e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:93ba8bb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:93bab3ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:93badc42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96618 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Holo-[acyl-carrieir-protein] synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:93bb044c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93bb2c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:93bb547e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:93bb7d3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:93bba546-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:93bbce68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:93bbf67c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:93bc208e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:93bc48ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:93bc70a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48066 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:93bc98b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48065 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:93bcc124-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31650 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:93bce94c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31646 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:93bd1232-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31649 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:93bd3b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23574 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:93bd6354-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid is agonist of GPCR (Gamma-aminobutyric acid type B receptor subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:93bd8b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSD5 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:93bdb368-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:93bdd816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:93bdfbfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Adenosine receptor A1) DrugCentral uuid:93be1fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) DrugCentral uuid:93be436e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:93be6736-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:93be904e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:93beb880-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:93bee09e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:93bf08a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:93bf3166-dc5e-11ec-be2c-0242ac110005 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:93bf5998-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.928']} DrugCentral uuid:93bf81ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:93bfaace-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:93bfd63e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:93c00082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93c02896-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:93c0510e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:93c0794a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:93c0a14a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:93c0c94a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:93c0f2bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:93c11b0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:93c1432a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:93c16b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:93c196ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93c1c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:93c1e938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:93c21174-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is negative allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:93c241f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:93c241f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:93c241f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:93c2800a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:93c2a80a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:93c2d082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:93c2f896-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:93c320aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:93c348b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:93c3730c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:93c396d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Kinase (Thymidine kinase) DrugCentral uuid:93c3baa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:93c3e2c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:93c40b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10210 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Enzyme (Capsid scaffolding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:93c43382-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:93c45c40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganirelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:93c47ffe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93c4a95c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:93c4d558-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:93c4d558-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:93c506e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:93c506e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:93c5391c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93c5391c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93c56c5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:93c59470-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:93c5bcb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93c5e588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:93c60dba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:93c635ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:93c65dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:93c6863c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:93c6ae50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:93c6d664-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:93c700f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:93c72948-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:93c75166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:93c77998-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:93c7a242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93c7ca4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:93c7f260-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93c81a56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:93c842c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:93c86baa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:93c893dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:93c8bbf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:93c8e51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:93c90d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:93c9354e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:93c95d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:93c9862a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:93c9ae48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:93c9d666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:93c9fe7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:93ca26f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:93ca4efc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:93ca7706-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:93ca9fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:93cacb16-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:93caf32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:93cb1c06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93cb44ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:93cb6d00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:93cb951e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:93cbbd46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:93cbe5be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:93cc0f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:93cc37bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93cc60d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:93cc8a1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:93ccb25a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:93ccdbb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:93cd03e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:93cd2cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:93cd5520-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:93cd7d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:93cda570-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:93cdce88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:93cdf692-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:93ce1ec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:93ce46d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:93ce702c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93ce984a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:93cec054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:93cee868-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:93cf11a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:93cf39d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:93cf620c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93cf8ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:93cfb2f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93cfdb88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:93d0037e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93d02cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:93d055ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:93d07dd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:93d0a5f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:93d0cf0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:93d0f720-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:93d11f48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93d14770-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:93d17056-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:93d1989c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:93d1c0c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:93d1e8ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:93d212e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Enzyme (Thymidylate synthase) DrugCentral uuid:93d2369e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:93d25a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:93d27e4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:93d2a250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30085 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Kinase (UMP-CMP kinase) DrugCentral uuid:93d2ced8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:93d2ced8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:93d2ced8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:93d30632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Lipoprotein lipase) DrugCentral uuid:93d329d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:93d3524a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93d37a5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:93d3a290-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:93d3caae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:93d3f5ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:93d41db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:93d44696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:93d46ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:93d48e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestodene targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:93d4b248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestodene targets Enzyme (Cytochrome P450 3A5) DrugCentral uuid:93d4d61a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1292 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestrinone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:93d4fe42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12882 biolink:molecularly_interacts_with DrugCentral:1293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gimeracil is inhibitor of Enzyme (Dihydropyrimidine dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:93d526c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:93d54ece-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:93d57ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:93d57ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:93d5b42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:93d5b42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:93d5efb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93d5efb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93d627cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:93d627cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:93d66232-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:93d66232-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:93d6995a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:93d6995a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:93d6d0a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:93d6d0a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:93d7080e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:93d7080e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:93d73f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:93d73f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:93d77384-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:93d7a0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:93d7c910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:93d7f138-dc5e-11ec-be2c-0242ac110005 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:93d819ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:93d84214-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:93d86a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00367 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 1, mitochondrial) DrugCentral uuid:93d88dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49448 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 2, mitochondrial) DrugCentral uuid:93d8b258-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:93d8da76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:93d902bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:93d92ada-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:93d95488-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:93d97eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93d9a6ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:93d9cefe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:93d9f76c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14416 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:93da1f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:93da47a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:93da6fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:93da9866-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:93dac084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.595']} DrugCentral uuid:93dae898-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.738']} DrugCentral uuid:93db10b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:93db3a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:93db6354-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:93db8b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:93dbb372-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:93dbdbfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:93dc0412-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:93dc2c44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:93dc5444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:93dc7d2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:93dca53e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.31']} DrugCentral uuid:93dccd52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03469 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:93dcf6a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70579 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:93dd1f50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47743 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:93dd4750-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:93dd7068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23385 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:93dd98d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31421 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:93ddc0cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31422 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:93dde8e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56068 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:93de111c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:93de3980-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:1311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:93de619e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2Q3 biolink:molecularly_interacts_with DrugCentral:1312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutathione targets Enzyme (Glutathione S-transferase kappa 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:93de9178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:93de9178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:93de9178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:93dec936-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:93def460-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:93df1ddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.795']} DrugCentral uuid:93df4604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:93df6f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:93df9b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:93df9b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:93dfce62-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:93dff680-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:93e01f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96P20 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Unclassified (NACHT, LRR and PYD domains-containing protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:93e04748-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:93e06f66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Nuclear other (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:93e09b80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:93e09b80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:93e0d4ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:93e0d4ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:93e10840-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:93e1304a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48067 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Transporter (Sodium- and chloride-dependent glycine transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:93e16f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e16f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e16f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e16f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e16f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e16f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e16f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e1da7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:93e20380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:93e22cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:93e254de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:93e27ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:93e2a92a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:1327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 goserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:93e2cd10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 goserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:93e2f100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:93e3195a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:93e3416e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93e369a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:93e391c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:93e3ba86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:93e3e290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00346 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:93e40a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0PJ46 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Lactate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:93e43268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6VVP7 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:93e45b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11708 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:93e48312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:93e4ab44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:93e4d362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52732 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Kinesin-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:93e4fbe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:93e523ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:93e54bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07195 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:93e57402-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:93e59cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93e5c4f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:93e5edf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:93e619e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:93e619e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:93e651f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:93e651f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:93e68522-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:93e6ad5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:93e6d5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:93e70218-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:93e70218-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:93e733aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:93e733aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:93e761b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10875 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Structural (Tubulin beta chain) DrugCentral uuid:93e78576-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:93e7aede-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:93e7deb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:93e7deb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:93e7deb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:93e816bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:93e83f5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:93e86784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanadrel is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:93e88b42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanadrel targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:93e8af5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:93e8d336-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:93e8f6cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:93e91a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:93e93ede-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:93e9629c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:93e98650-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:93e9ab12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.065']} DrugCentral uuid:93e9d420-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:93e9fc52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:93ea2484-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.926']} DrugCentral uuid:93ea4cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:93ea751a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:93ea9d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:93eac588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:93eaedb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.164']} DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ebac64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ed8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:93ee442e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ulobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:93ee6800-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halofantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:93ee901e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:93eeb8dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:93eee0dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:93ef08fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:93ef310e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.947']} DrugCentral uuid:93ef5a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:93ef826c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:93efaa80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:93efd294-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:93effb20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93f02334-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93f04b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:93f0742e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:93f09cd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:93f0c4ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:93f0ed00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:93f1150a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:93f13fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:93f167da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:93f1900c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:93f1b884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:93f1e1ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:93f209d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:93f2320a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:93f25ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:93f282d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:93f2aaf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.569']} DrugCentral uuid:93f2d32c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:93f2fcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:93f327fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:93f350a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:93f38178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93f38178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93f38178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93f3c070-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.648']} DrugCentral uuid:93f3e88e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:93f410c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:93f43988-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:93f4619c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:93f489a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:93f4b1c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:93f4dc76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:93f507be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.76']} DrugCentral uuid:93f52ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:93f55818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:93f580a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:93f5a9b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:93f5d1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:93f5fa70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:93f6228e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:93f64a8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:93f672c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93f69c00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:93f6c75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:93f6f1e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:93f719fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:93f7427c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:93f76b6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:93f793da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:93f7bc0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:93f7e4de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:93f80d1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:93f83542-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:93f85d60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:93f88772-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50129 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:93f8af9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:93f8d7c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:93f8ffe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62744 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (AP-2 complex subunit sigma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:93f93898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93f93898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93f93898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93f93898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93f93898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:93f999b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93f999b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93f999b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93f999b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93f9ef36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:93f9ef36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:93f9ef36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:93f9ef36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:93fa40a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:93fa40a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:93fa40a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:93fa87f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:93fa87f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:93faca46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93faca46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93faca46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93faca46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93faca46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:93fb26bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93fb26bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93fb26bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:93fb6c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:93fb6c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:93fb6c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fbc6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:93fc44fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:93fc44fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:93fc44fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:93fc84c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:93fcace4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:93fcd570-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:93fcfdb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:93fd25f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60493 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (Zinc finger protein 664) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:93fd4ece-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:93fd770a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halopredone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:93fd9adc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:93fdc2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.339']} DrugCentral uuid:93fdebf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.366']} DrugCentral uuid:93fe1552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.561']} DrugCentral uuid:93fe3df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:93fe6610-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:93fe8e9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:93feb6c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:93fedfdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:93ff07f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:93ff30b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:93ff58d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:93ff80ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.338']} DrugCentral uuid:93ffa8f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:93ffd202-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:93fffa34-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:94001e06-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:940041d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:9400660e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:940089ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:9400b190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:9400b190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:940118ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9401d020-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9401f83e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:9402207a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin targets Unclassified (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:940248e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:94027110-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:94029942-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9402c174-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9402ea32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:9403123c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:94033a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:94036264-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:94038cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9403c808-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:9403c808-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:9403c808-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:9403c808-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:9403c808-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:9403c808-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:94041c9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.212']} DrugCentral uuid:94044558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.191']} DrugCentral uuid:94046d6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.043']} DrugCentral uuid:9404958a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.686']} DrugCentral uuid:9404be48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:9404e67a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:94050e98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:940536ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:94056226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:94058a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:9405b38e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.521']} DrugCentral uuid:9405dc2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:94060442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.882']} DrugCentral uuid:94062c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.126']} DrugCentral uuid:94065474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.911']} DrugCentral uuid:94067da0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06149 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (D-lactate dehydrogenase) DrugCentral uuid:9406a17c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.614']} DrugCentral uuid:9406c9a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.459']} DrugCentral uuid:9406f1b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.479']} DrugCentral uuid:94071af8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:940745f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:94076fe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.057']} DrugCentral uuid:94079816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:9407c084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.479']} DrugCentral uuid:9407e8ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:940810ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) DrugCentral uuid:94083492-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:94085d32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:94088550-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:9408ad50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:9408d550-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9408ffb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:940929b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:940952be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:94097b72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9409a3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:9409cc08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:9409efee-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:940a182a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:940a44e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:940a44e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:940a7c16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:940a7c16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:940ab316-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:940ab316-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:940af4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:940af4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:940af4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:940af4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:940b3fac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:940b6842-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:940b9042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexestrol is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:940bc01c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:940bc01c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:940bc01c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:940bff5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:940bff5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:940bff5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:940c3e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:940c3e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:940c3e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:940c7dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:940c7dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:940c7dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:940cbdbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:940cbdbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:940cbdbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:940cfc16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:940d1ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:940d4888-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:940d70ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:940d98ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:940dc11e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:940df1a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:940df1a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:940df1a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:940e2fe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:940e57f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:940e8130-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:940ea94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:940ed16c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:940ef980-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:940f21f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.508']} DrugCentral uuid:940f4b4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:940f734c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:940f9d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:940fc568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:940fed72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9410159a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:94103eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:94106928-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9410913c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:9410b950-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91ZY3 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9410e1c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histidine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:941109be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:941131e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:94115a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:941182cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:9411aaea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:9411d308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hycanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9411fb3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9412257e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:941249aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:94126d54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:9412913a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:9412b598-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9412ddac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.438']} DrugCentral uuid:941305ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94132dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:94135688-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:94137e88-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0LPN4 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.152']} DrugCentral uuid:9413a7a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine is blocker of Ion channel (Ryanodine receptor 2) DrugCentral uuid:9413cb7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9413f4b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.01']} DrugCentral uuid:94141c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:941444b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:94146870-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:94148ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9414b4d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9414dcec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9415064a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:94152f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:941557e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:94158016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocodone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9415a848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortamate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9415cdf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9415f60e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Cytosolic other (Annexin A1) DrugCentral uuid:941619d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.95']} DrugCentral uuid:941641d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:94166a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.881']} DrugCentral uuid:9416924e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9416ba6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.37']} DrugCentral uuid:9416e28a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone cypionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:941706e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.37']} DrugCentral uuid:94172f10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:94175742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:94177f74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9417b7b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9417b7b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9417b7b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9417b7b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:941803fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.1']} DrugCentral uuid:94182c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:941854a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.529']} DrugCentral uuid:94187cbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9418a4ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9418cd8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:9418f16a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:9419199c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.81']} DrugCentral uuid:941941b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:94196b5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:94199516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9419bd52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9419e584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:941a0dfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:941a31ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:941a59f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:941a8340-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:941aac80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:941ad494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxystilbamidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:941afc76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:941b2494-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:941b4e74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:941b7250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:941b9604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:941bbe18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:941be69a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:941c0ed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:941c36ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.409']} DrugCentral uuid:941c5f12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:941c87c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:941cafe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:941cd7ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:941d0002-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:941d2a8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:941d5296-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:941d7aa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:941da2c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:941dcb5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:941df390-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:941e1ba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:941e4476-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:941e6c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:941e94c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:941ebcd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:941ee5e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:941f0dfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:941f36f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:941f5f14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:941f8796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:941fafc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:941fd7f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:94200022-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:942028fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:94205234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:942075fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:94209e2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9420c8e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9420f162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:94211980-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:94214194-dc5e-11ec-be2c-0242ac110005 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:94216a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9421920c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9421ba20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9421e22a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:94220aca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:942236bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:942236bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:942269fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:94229350-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VD48 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9422bd4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.53']} DrugCentral uuid:9422e56c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9423123a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9423123a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:942345de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibutilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:94236e06-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75907 biolink:molecularly_interacts_with DrugCentral:1413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icosapent ethyl is inhibitor of Enzyme (Diacylglycerol O-acyltransferase 1) DrugCentral uuid:942391e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9423b636-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:9423da9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:9423fe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:94242666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:94244e98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:94247792-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:94249fc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:1417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idoxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9424c800-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:1417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idoxuridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9424f028-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:942518aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:942540b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:942568e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:94259104-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9425b9e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9425e58c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:94260df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:942636fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:94265fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:942687d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9426afee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9426d870-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.99']} DrugCentral uuid:94270566-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:94270566-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:94274058-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:94274058-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:94274058-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:94277f64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00960 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate [NMDA] receptor subunit epsilon 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9427a782-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60490 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Unclassified (3-beta-hydroxysteroid-delta(8),delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:9427cfc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9427f80e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:94282108-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:942849da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:94287400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:94289c0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9428c4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:9428ecb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:942914fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:94293d18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:942965ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:94298e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9429b8c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9429e146-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:942a096e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:942a3196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:942a59c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:942a8254-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:942aab58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:942ad362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:942afb76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:942b2448-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:942b4cb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:942b74de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:942b9e78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:942bc7ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:942bf012-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:942c13ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:942c3c16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:942c6506-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:942c8dc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:942cb5d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:942cddec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:942d0682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:942d2eaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:942d56d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:942d7ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:942da970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:942dd1b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:942df9de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:942e2292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:942e4ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:942e72e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:942e9bdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:942ec468-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:942eec86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:942f14a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:942f3cb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:942f660c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:942f8e3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:942fb684-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:942fdeac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:94300792-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94302fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:943057f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9430801e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9430a8a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9430d0b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9430f8be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:943120fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:94314abc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:943172e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:94319c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9431c44c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9431edb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:943215d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:94323df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:943265fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:94328f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9432b776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9432df94-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:94330988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:943331b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:943359ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:943381f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9433aafa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9433d30e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9433fb36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:94342368-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:94344bfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:94347426-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:94349c3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9434c44e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9434ed70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9435158e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:94353da2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:943565ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:94358e92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:9435b6a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9435deb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:943606e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:94362f50-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9436575a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9436804a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9436a872-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:9436d5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9436d5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:94370cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:94370cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:94374408-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:94374408-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9437795a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05030 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:9437a18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9437c9aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9437f218-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:94381a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:94384272-dc5e-11ec-be2c-0242ac110005 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:943881ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:943881ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:943881ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:943881ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:943881ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:943881ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:943881ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9438e510-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:94390d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:943935f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:94395ebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.854']} DrugCentral uuid:943986fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.432']} DrugCentral uuid:9439af18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:9439d8c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:943a00f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:943a290c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:943a512a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:943a7bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:943aa40e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.614']} DrugCentral uuid:943acc18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:943af4ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:943b1ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:943b4526-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:943b6d4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.081']} DrugCentral uuid:943b9634-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:943bbe7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:943be6a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:943c0ec0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:943c3774-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:943c5f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:943c87ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:943cb12c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:943cd9c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:943d01e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:943d29f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:943d523a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:943d7b0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:943da32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:943dcc2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:943df456-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:943e1e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:943e5d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:943e5d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:943e5d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:943e5d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:943e5d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:943e5d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:943e5d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:943ed6fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:943ed6fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:943ed6fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:943ed6fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:943ed6fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:943f5dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:9440241a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9440241a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9440241a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:94407366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:94407366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:94407366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:94407366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:94407366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9440cffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9440cffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9440cffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9441179e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9441179e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9441179e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:94415d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:94415d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:94415d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:94419bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9441c694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9441f1be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:944219d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:944242e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:94426b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:944293c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod is agonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:9442bbda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9442e4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8MTZ4 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid targets Unclassified (Vacuolar-type proton translocating pyrophosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:94430cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:94433524-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indalpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:94435d38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9443863c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9443ae3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:9443d66e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:9443fea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:94442718-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:94444f22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) DrugCentral uuid:944472f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:94449b1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:9444c3bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:9444ebe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:94451524-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:94453d42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.535']} DrugCentral uuid:94456754-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:94459148-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9445b97a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9445dd1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indenolol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:9446013c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indenolol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:94462504-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:94464df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:944675fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.733']} DrugCentral uuid:94469e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9446c720-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9446ef34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9447175c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:944741c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:94476c5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:9447947a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9447bca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:9447e54c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:94480d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:94483132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:9448550e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:94487de0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9448a608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:9448ce12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9448f626-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:94491ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:94494716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:94496ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:944996f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:9449bf66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9449e770-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:944a0f7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.691']} DrugCentral uuid:944a382e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:944a613c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:944a8964-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:944ab150-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:944ada9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:944b03d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:944b2be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:944b5420-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:944b7c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:944ba48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:944bccb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:944bf4ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:944c1d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:944c4574-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:944c7152-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:944c7152-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:944ca9ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:944ca9ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:944ce47a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:944ce47a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:944d17a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:944d3fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:944d6814-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17516 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:944d901e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:944db832-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:944de10e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:944e0a44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:1442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoprofen targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:944e3262-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:944e5a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:944e8384-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:944eabac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:944ed3e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:944efc06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:944f2488-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:944f4cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:944f74ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:944fa494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:944fa494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:944fa494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:944feb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:944feb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:944feb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:94502ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:945053c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:94507c34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9450a452-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.278']} DrugCentral uuid:9450cc5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.724']} DrugCentral uuid:9450f51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.609']} DrugCentral uuid:94511d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.804']} DrugCentral uuid:9451452e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.067']} DrugCentral uuid:94516d1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.279']} DrugCentral uuid:945196a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.439']} DrugCentral uuid:9451beaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.043']} DrugCentral uuid:9451e6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.532']} DrugCentral uuid:94520ebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:94523808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:94526030-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:94528876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.292']} DrugCentral uuid:9452b102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.181']} DrugCentral uuid:9452d98e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:945301ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:945329d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:945351fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.74']} DrugCentral uuid:94537ace-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:9453a2ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipriflavone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:9453caec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipriflavone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:9453f30a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:94541d80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:9454458a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:94546d9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.185']} DrugCentral uuid:9454962a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9454be34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9454e666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:94550e7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:94553742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:94555f56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:94558846-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9455b44c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9455b44c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9455f24a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9455f24a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9455f24a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:94563138-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9456596a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:94567d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:9456a596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:9456c95e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:9456f17c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:945715d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:94573970-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:94575d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:94578556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:9457aaa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:9457d4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9457fcca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:945824de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:94584d38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9458754c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:94589d4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:9458c54c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irofulven targets Kinase (Serine/threonine-protein kinase Chk2) DrugCentral uuid:9458ea2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isepamicin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.87']} DrugCentral uuid:94591268-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1490 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:94593662-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1490 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:94595b42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoetarine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:945984fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:9459af48-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:9459d324-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:9459f700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:945a1b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:945a3f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:945a66f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:945a66f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945ace0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:945b8778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:945bafb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:945bd7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:945c0072-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:945c2994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:945c51b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q29550 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Liver carboxylesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:945c79c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:945ca27a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Catalase-peroxidase) DrugCentral uuid:945cc674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:945cee88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:945d16b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:945d3fa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:945d67fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:945d902c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:945db854-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:945de0f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:945e0930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:945e3158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:945e5a0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.752']} DrugCentral uuid:945e8220-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:945eaa2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:945ed23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:945efb4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:945f268a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:945f4ea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:945f76bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:945fa060-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:945fc89c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:945ff0ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:946018f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94604290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59534 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94606ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59535 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 40) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:946092ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59536 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9460bb26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59537 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 43) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9460e48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59538 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 31) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94610cac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59539 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 45) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:946134ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94615cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59541 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 30) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94618560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59542 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 19) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9461ad7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59543 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9461d5a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59544 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 50) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9461fdd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59551 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 60) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:946226b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTR8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 42) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94624ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYV7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 16) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:946276fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94629fb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYV9 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9462c812-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9462f030-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW1 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9463184e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW2 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:946340e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW3 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:946369a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:946391b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW5 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9463b9c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW6 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9463e26a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94640aba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:94642f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:94645344-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:9464845e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9464845e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9464845e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9464845e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9464c752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:9464f678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9464f678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9464f678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9464f678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:94653926-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:94656162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:94658980-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:9465b252-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:9465da5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08319 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (Alcohol dehydrogenase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:9466027a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:94662a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9466534c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14756 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (17-beta-hydroxysteroid dehydrogenase type 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:94667b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin is inhibitor of Nuclear hormone receptor (Retinoic acid receptor beta) DrugCentral uuid:94669f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.597']} DrugCentral uuid:9466c78c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.335']} DrugCentral uuid:9466f004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9467182c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9467404a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1509 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:94676868-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1509 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:94679144-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:9467b50c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:9467da28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9468026e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:94682c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:94685674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:94687eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9468a6e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9468cf78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9468f822-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:94692068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:9469489a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.246']} DrugCentral uuid:9469719e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:946999d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9469c1f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9469ea20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:946a1464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:946a3c82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:946a6496-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:946a8e3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:946ab68a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946afd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:946b702a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:946b987a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:946bc0a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29033 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Unclassified (Gap junction beta-2 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:946bec26-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:1520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bekanamycin targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:946c164c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bekanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:946c3e6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:946c7e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:946c7e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:946c7e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:946c7e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:946c7e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:946c7e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:946c7e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:946cff6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:946cff6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:946cff6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:946cff6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:946cff6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:946cff6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:946cff6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:946d7596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:946d7596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:946d7596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:946d7596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:946dbdbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:946de5ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:946e0e2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki'} DrugCentral uuid:946e385a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:946e6064-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:946e888c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:946eb0b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:946ed990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:946f01e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:946f2a30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:946f5262-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:946f7bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:946fa672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:946fceb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:946ff6fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.747']} DrugCentral uuid:94701fda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:94704802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:94707020-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:9470983e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:9470c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9470e942-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9471116a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:94713992-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.903']} DrugCentral uuid:947164a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:94718cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9471b61a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9471de6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9472070a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.33']} DrugCentral uuid:94722f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:947257a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:94728144-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9472aba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9472db62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9472db62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9472db62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:947322fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:947322fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:947322fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:947361b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:947389fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9473b1fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9473dbac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:947403ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.585']} DrugCentral uuid:94742bde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:9474602c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9474602c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9474602c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9474602c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9474b4be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9474b4be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9474b4be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9474b4be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9474fffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.821']} DrugCentral uuid:9475282c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:947550fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:94757930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9475a1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:9475ca20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9475f248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:94761a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:9476434c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.667']} DrugCentral uuid:94766b9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:947693b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:9476bbce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.729']} DrugCentral uuid:9476e568-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:9477096c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:947731d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:947759f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:94778310-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9477abc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9477d3f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9477fc96-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:947824be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:94784d54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:9478757c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.665']} DrugCentral uuid:94789fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'app Ki', 'has_quantitative_value': ['7.197']} DrugCentral uuid:9478c7f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9478f010-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9479195a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9479439e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:94796bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.266']} DrugCentral uuid:9479940c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.897']} DrugCentral uuid:9479bc5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.211']} DrugCentral uuid:9479e4fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:947a0d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:947a3556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:947a5d88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07973 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.506']} DrugCentral uuid:947a86d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08686 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 21) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:947aaef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:947ad704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14137 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:947aff18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09128 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 24A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:947b2858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18125 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 7A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:947b508a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64654 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 51) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:947b78da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:947ba116-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:947bc998-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35084 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:947bf1b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:947c19e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:947c433c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.896']} DrugCentral uuid:947c6bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:947c94f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:947cbd1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:947ce65c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:947d1262-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:947d1262-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:947d45b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:947d6de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:947d967e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:947dbee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.214']} DrugCentral uuid:947de6f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:947e0f28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:947e389a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.361']} DrugCentral uuid:947e60e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:947e8912-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:947eacee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.839']} DrugCentral uuid:947ed76e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.047']} DrugCentral uuid:947effb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:947f27d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:947f5072-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:947f78b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.489']} DrugCentral uuid:947fa0e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:947fc912-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.509']} DrugCentral uuid:947ff28e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:94801c96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:94804496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:94806caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:94809658-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:9480be8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.075']} DrugCentral uuid:9480e6bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:94810eda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:948137a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:94815fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:948187fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.234']} DrugCentral uuid:9481b04c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:9481da7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.117']} DrugCentral uuid:948202c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.478']} DrugCentral uuid:94822b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:9482534e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:94827c2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:9482a452-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:9482cc7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:9482f4b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:94831d4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:94834560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:94836d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9483966e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9483c008-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:9483e812-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.245']} DrugCentral uuid:9484104e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:9484392a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:94846152-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:94848a6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:9484b292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.771']} DrugCentral uuid:9484dcb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:948508dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:948508dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9485367c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00214 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:94855e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00182 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.64']} DrugCentral uuid:948588a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17931 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.03']} DrugCentral uuid:9485b0ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:9485d4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine is inhibitor of Polyprotein (Protein P) DrugCentral uuid:9485f88c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:94862172-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:94864972-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.839']} DrugCentral uuid:9486717c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:94869562-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9486bdf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9486e62a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:94870e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:94873242-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:94875c40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.744']} DrugCentral uuid:9487847c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:9487ac9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:9487d4cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9488053c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:9488053c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:9488053c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:94884484-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:94886cac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1545 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 landiolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:9488910a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:9488b93c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9488e18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:948909c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:94893542-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:94895da6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:948985e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:9489ae14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:9489d6f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9489ff22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:948a274a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.275']} DrugCentral uuid:948a4fe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.473']} DrugCentral uuid:948a790c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:948aa1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCT1 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Phosphoethanolamine/phosphocholine phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:948ac9d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:948af31e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:948b1f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:948b1f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:948b4cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:948b74e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:948b9d64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:948bc564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:948be922-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:948c0ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:948c3634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:948c5e7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:948c86ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:948caf06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:948cd472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:948cfca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:948d24d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:948d4cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:948d759e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:948d9db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:948dc5e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:948dedf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:948e1698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:948e3ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:948e671a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:948e8f38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:948eba62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:948ee280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1549 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine hydrochloride targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:948f0ab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:1549 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine hydrochloride is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:948f332a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75746 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar1) DrugCentral uuid:948f56de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17174 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, cytoplasmic) DrugCentral uuid:948f7aa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45381 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartoacylase) DrugCentral uuid:948f9e64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08243 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Asparagine synthetase [glutamine-hydrolyzing]) DrugCentral uuid:948fc22c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00966 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Argininosuccinate synthase) DrugCentral uuid:948fe63a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03154 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aminoacylase-1) DrugCentral uuid:94900b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00505 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, mitochondrial) DrugCentral uuid:94903004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14868 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate--tRNA ligase, cytoplasmic) DrugCentral uuid:949053cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12797 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartyl/asparaginyl beta-hydroxylase) DrugCentral uuid:9490792e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9490a1d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9490ca00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:9490f214-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UJS0 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar2) DrugCentral uuid:94912ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:94912ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:94912ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:94912ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:94912ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:94912ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:94912ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:949197aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9491c022-dc5e-11ec-be2c-0242ac110005 UniProtKB:O59010 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Glutamate transporter homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:9491e82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.757']} DrugCentral uuid:9492104a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:94923886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:949262a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:94928ac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:9492b2de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:9492db60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9493039c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:94932ba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:949353c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.684']} DrugCentral uuid:94937d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9493a540-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9493cd5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9493f57c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:94941e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:949446e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:94946ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leuprorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:9494972a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leuprorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9494bfac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:9494e7f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:94951010-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:949544c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:949544c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:949544c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:949544c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:94958e64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N587 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Ion channel (Acetylcholine receptor subunit alpha-type unc-63) DrugCentral uuid:9495b218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9495da72-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96760 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole is agonist of Ion channel (Nicotinic acetylcholine receptor alpha subunit) DrugCentral uuid:94960038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.568']} DrugCentral uuid:949628ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09487 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:94965100-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:9496790a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:9496a18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9496c996-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:9496f1a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:94971aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94977440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94983128-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:94985536-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:94987912-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:94989d0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9498c534-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9498ed48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9499117e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.279']} DrugCentral uuid:949939c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95665 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9499630e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63384 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine targets GPCR (Neurotensin receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:94998b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70310 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9499b638-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:9499df96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:949a07c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.541']} DrugCentral uuid:949a3054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:949a587c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:949a80ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:949aa8c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa is agonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:949acd02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa is agonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:949af0de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.04']} DrugCentral uuid:949b18f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:949b4106-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:949b6eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:949b6eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:949ba060-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:949ba060-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:949bcdf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:949bf61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadyl acetate is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:949c1a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadyl acetate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:949c42e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:949c6b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:949c9330-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:949cb75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['12.796']} DrugCentral uuid:949cdf66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.91']} DrugCentral uuid:949d077a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:949d2fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.339']} DrugCentral uuid:949d5b4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:949d852e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:949dad56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:949dd6e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:949dfef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:949e270e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:949e4f36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:949e77a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:949e9fc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:949ec7ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55242 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:949f0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:949f0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:949f0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:949f0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:949f0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:949f0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:949f0836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:949f9210-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:949f9210-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:949f9210-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:949f9210-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:949f9210-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:949f9210-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:949f9210-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:94a00880-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:94a00880-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:94a00880-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:94a00880-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:94a05ace-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:94a05ace-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:94a05ace-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:94a0991c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:94a0c14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosalbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:94a0eafc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:94a10eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:94a1328c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15842 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 8) DrugCentral uuid:94a15668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63316 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan is opener of Cytosolic other (Troponin C, slow skeletal and cardiac muscles) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.155']} DrugCentral uuid:94a17ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:94a1a73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:94a1cf6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:94a1f816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:94a22084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:94a248ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:94a27ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:94a27ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:94a27ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:94a27ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:94a27ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:94a2df1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:94a2df1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:94a2df1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:94a32524-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:94a32524-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:94a32524-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:94a364c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:94a38cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:94a3b0e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:94a3d910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:94a40192-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:94a4299c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.296']} DrugCentral uuid:94a451b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:94a47564-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.559']} DrugCentral uuid:94a4a610-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:94a4a610-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:94a4a610-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:94a4ec38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:94a4ec38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:94a4ec38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:94a52aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:94a552f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:94a57afe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:94a5a34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:94a5d35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:94a5d35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:94a5d35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:94a611d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 limaprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:94a63598-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:1582 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lincomycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:94a65960-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:94a68264-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:94a6ab68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75NA5 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:94a6d390-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:94a703ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:94a703ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:94a703ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:94a749ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:94a749ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:94a749ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:94a789f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:94a789f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:94a789f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:94a7c94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94a7c94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94a7c94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94a80fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:94a80fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:94a80fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:94a85134-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:94a87a38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:94a8a260-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:94a8ca60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31040 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:94a8f2f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:94a91b3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:94a9435a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:94a96bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:94a993fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:94a9bd08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:94a9e51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94aa49b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ab52b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:94ac244e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1587 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:94ac4c62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1587 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:94ac749e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:94ac9d7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:94acc5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:94acedd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:94ad1642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.936']} DrugCentral uuid:94ad3e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:94ad6688-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.061']} DrugCentral uuid:94ad8ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:94adb782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.259']} DrugCentral uuid:94addfb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:94ae07be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.625']} DrugCentral uuid:94ae2fdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:94ae58cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:94ae80fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:94aeaa02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:94aed248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:94aefad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:94af22fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.203']} DrugCentral uuid:94af4b10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:94af74c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:94af9f7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.037']} DrugCentral uuid:94afc9aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:94aff1dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:94b01a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.338']} DrugCentral uuid:94b042c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:94b06acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:94b092b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.33']} DrugCentral uuid:94b0bacc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:94b0e362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:94b10b9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.489']} DrugCentral uuid:94b133bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:94b15cb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:94b185e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:94b1ae1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:94b1d63c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:94b1ff18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:94b2275e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.444']} DrugCentral uuid:94b24f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:94b2777c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:94b2a0da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:94b2c8f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.468']} DrugCentral uuid:94b2f120-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:94b31948-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:94b342a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:94b36ad8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:94b392f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:94b3c29e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:94b3c29e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:94b3c29e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:94b4092a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:94b4092a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:94b4092a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:94b4478c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:94b47054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:94b49cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:94b49cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:94b4cb76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomerizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:94b4f394-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonazolac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:94b51d10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:94b5454c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:94b56d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:94b5956a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:94b5b9aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:94b5e24a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:94b60a5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:94b63362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.343']} DrugCentral uuid:94b65c2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:94b6843e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:94b6ac5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:94b6d452-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:94b6fb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:94b7238a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:94b74ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:94b77bc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:94b77bc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:94b77bc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:94b7b2fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:94b7db04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.345']} DrugCentral uuid:94b8032c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) DrugCentral uuid:94b82794-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) DrugCentral uuid:94b84b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) DrugCentral uuid:94b86f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:94b89760-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:94b8c190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:94b8eae4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:94b9130c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:94b93b34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:94b963a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:94b98bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:94b9bb86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:94b9bb86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:94b9bb86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:94b9fb0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:94ba22f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:94ba4c4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:94ba7468-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:94ba9e20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:94bac1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:94baea42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:94bb126a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:94bb3ad8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.59']} DrugCentral uuid:94bb6300-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:94bb92a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:94bb92a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:94bb92a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:94bbd20e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:94bbd20e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:94bbd20e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:94bc114c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:94bc114c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:94bc114c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:94bc4fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:94bc4fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:94bc4fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:94bc8898-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:94bcc2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:94bcc2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:94bcc2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:94bcc2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:94bcc2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:94bcc2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:94bcc2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:94bd221c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:94bd4a4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:94bd7294-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:94bd9b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:94bdc3ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:94bdebac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:94be13c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:94be3c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:94be64a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:94be8dd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:94beb5fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2J7 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Transporter (Sodium-dependent neutral amino acid transporter B(0)AT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:94bede72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:94bf06a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:94bf367e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:94bf367e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:94bf367e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:94bf7562-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:94bf9920-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:94bfbce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:94bfe09c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:94c00554-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:94c02ade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.498']} DrugCentral uuid:94c052fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:94c07b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:94c0a3ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:94c0cbd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:94c0f4dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:94c11cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:94c14590-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:94c16da4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:94c195ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:94c1bdd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WV26 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:94c1ea9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:94c1ea9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:94c22960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:94c22960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:94c22960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:94c22960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:94c27776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:94c27776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:94c2b236-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:94c2b236-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:94c2b236-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:94c2f430-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:94c2f430-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:94c32824-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCN6 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Unclassified (Platelet glycoprotein VI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:94c3504c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loteprednol etabonate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:94c37540-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:94c39d68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:94c3c66c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:94c3ee94-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:94c416c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.67']} DrugCentral uuid:94c43fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:94c46838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:94c49056-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:94c4b86a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:94c4e074-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:94c50946-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:94c53150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.697']} DrugCentral uuid:94c55978-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:94c582ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:94c5aad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01237 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:94c5d2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:94c5fb08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:94c62358-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95214 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Acyl-CoA:cholesterol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:94c64b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:94c67394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:94c69bb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:94c6c45c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.244']} DrugCentral uuid:94c6ec70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:94c714c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:94c73cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:94c765d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:94c78dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:94c7b5ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:94c7de28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:94c8068c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:94c82f86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:94c857b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:94c87fb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:94c8a88a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:94c8d08a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.376']} DrugCentral uuid:94c8f92a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:94c9213e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:94c94b8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.829']} DrugCentral uuid:94c974fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:94c99d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:94c9c594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:94c9ee34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:94ca1666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:94ca3e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.276']} DrugCentral uuid:94ca6742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:94ca8f6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:94cab77e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:94cadf92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:94cb0850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:94cb3078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:94cb5896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:94cb80be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:94cba922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:94cbd118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:94cc00e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:94cc00e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:94cc00e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:94cc4102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:1614 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:94cc6916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:1614 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxiglumide is antagonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:94cc913e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:94ccb970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:94cce24c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lucanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:94cd0a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumefantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:94cd324c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:94cd5a6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:94cd8364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:94cdab82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:94cdd3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:94cdfbbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.979']} DrugCentral uuid:94ce2422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.856']} DrugCentral uuid:94ce4c4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.12']} DrugCentral uuid:94ce7468-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:94ce9c90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:94cec580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:94ceeda8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:94cf15b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:94cf3ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:94cf67ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:94cf8fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:94cfb878-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:94cfe1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:94d00a12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:94d03244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:94d05a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:94d083d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:94d0ae22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:94d0d654-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:94d0fe72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:94d12f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:94d12f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:94d12f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:94d16d6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:94d19594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:94d1be0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:94d1e634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:94d20e5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:94d2368e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:94d25fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:94d28396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:94d2aba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:94d2d3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:94d2fcb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:94d324d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:94d34cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:94d374fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:94d39d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:94d3c652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:94d3ee70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:94d41670-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:94d44082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:94d4688c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:94d490be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:94d4b8fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:94d4e1a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:94d50af8-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:94d5330c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:94d55bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:94d5846a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:94d5ac88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:94d5d4ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:94d5fdb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:94d625e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:94d64e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:94d67604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 malathion targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.538']} DrugCentral uuid:94d69f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2PZ98 biolink:molecularly_interacts_with DrugCentral:1626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 malathion is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:94d6c2ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:94d6eee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:94d6eee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:94d71c4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.308']} DrugCentral uuid:94d744bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:94d76cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.165']} DrugCentral uuid:94d7950c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.364']} DrugCentral uuid:94d7bdfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:94d7e854-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.27']} DrugCentral uuid:94d81248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:94d83a5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:94d8627a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:94d88b42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:94d8b360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.854']} DrugCentral uuid:94d8db6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.876']} DrugCentral uuid:94d90392-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:94d92c0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:94d95432-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.777']} DrugCentral uuid:94d97c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.406']} DrugCentral uuid:94d9a52c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:94d9cf52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:94d9f77a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:94da1f66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:94da482e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.939']} DrugCentral uuid:94da701a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:94da9824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.355']} DrugCentral uuid:94dac01a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:94dae9a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:94db11b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:94db3586-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:94db5d86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:94db875c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:94dbb04c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:94dbd888-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc is antagonist of GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:94dc00c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:94dc2982-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:94dc51b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61813 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:94dc79be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:94dca1d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:94dcca40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:94dcf24a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:94dd1a68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:94dd427c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:94dd6d92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:94dd98b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:94ddc24c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:94ddeb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:94de1314-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:94de3b28-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:94de6332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:94de8bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:94deb3c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:94dedbdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:94df03d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:94df2d4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:94df56ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:94df829e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:94df829e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:94dfb70a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:94dfdfbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:94e007b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:94e02fc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:94e057dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:94e08054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:1638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maxacalcitol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:94e0a994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:1638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maxacalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:94e0d1a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:94e0fb7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:94e125d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:94e14dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:94e1761c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:94e19ee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:94e1c702-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:94e1ef20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:94e21734-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:94e23f8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:94e267a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:94e28fac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BJF5 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Calmodulin-domain protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:94e2bf5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e2bf5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e2bf5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e310b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e310b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e310b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e310b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e310b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e310b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e310b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:94e37034-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:94e3987a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (Histamine H4 receptor) DrugCentral uuid:94e3bc4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:94e3e460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:94e40cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.161']} DrugCentral uuid:94e434e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:94e460c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:94e460c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:94e497ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:94e497ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:94e4d32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:94e4d32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:94e50d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:94e50d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:94e544fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:94e544fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:94e584e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:94e584e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:94e584e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:94e584e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:94e5ce24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:94e5f782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:94e61fa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:94e647be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:94e66fe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:1648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecillinam is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.035']} DrugCentral uuid:94e698e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:94e6c0fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:94e6e4d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is agonist of Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:94e70d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:94e736ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:94e75f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:94e7871e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:94e7afa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:94e7d7be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:94e7ffe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:94e82804-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:94e85158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:94e87b4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:94e8a37e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:94e8cbba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.503']} DrugCentral uuid:94e8f45a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:94e91c78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:94e94482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:94e97060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:94e97060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94e9dcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:94eab646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:94eab646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:94eab646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:94eafcdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:94eafcdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:94eafcdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:94eb42b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:94eb42b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:94eb42b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:94eb88e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:94eb88e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:94eb88e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:94ebc860-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxalol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['7.82']} DrugCentral uuid:94ebf074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['6.08']} DrugCentral uuid:94ec1a90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.561']} DrugCentral uuid:94ec42d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:94ec6b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:94ec9416-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:94ecbc3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.59']} DrugCentral uuid:94ece434-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:94ed0c48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:94ed34ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:94ed5d60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:94ed8574-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:94edad88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:94edd754-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.032']} DrugCentral uuid:94ee01b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:94ee2ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:94ee2ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:94ee61d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1662 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medrysone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:94ee864a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:94eeae7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:94eed686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:94eefe72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:94ef26cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:94ef4fda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:94ef7802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:94efa156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:94efc988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:94eff1a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:94f019a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:94f0425a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:94f06a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:94f09278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:94f0ba96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:94f0e2f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:94f106c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:94f12ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:94f152a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:94f17bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P90584 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Unclassified (Protein kinase Pfmrk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:94f1a51e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:94f1c8e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.057']} DrugCentral uuid:94f1f118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:94f21580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:94f23d94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:94f265b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:94f28dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meglutol targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:94f2b634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:94f2de7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:94f306a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:94f32f2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:94f359e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:94f381e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:94f3a9ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:94f3d320-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:94f3fc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:94f42bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:94f42bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:94f42bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:94f46a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:94f4927e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:94f4baba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:94f4e2e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:94f50b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:94f53422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:94f55c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:94f58422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:94f5ac2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:94f5d4ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:94f5f8c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:94f620e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:94f64916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:94f6717a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:94f69998-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.063']} DrugCentral uuid:94f6c1a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:94f6e9ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:94f71328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:94f73c4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.469']} DrugCentral uuid:94f7647c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:94f78858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:94f7b12a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:1678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melphalan targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:94f7d95c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:94f7fd2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:94f8211e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:94f849aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:94f871aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:94f89dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:94f89dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:94f8d64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:94f8d64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:94f909e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:94f931ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:94f95b4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:94f9841e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:94f9ac3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:94f9d45a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30305 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:94f9fcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:94fa24dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30307 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:94fa4cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15374 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Ubiquitin carboxyl-terminal hydrolase isozyme L3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:94fa74fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94fa9df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64346 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:94fac798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28563 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:94faf07e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:94fb18b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:94fb4150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione sodium bisulfite targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:94fb6978-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1685 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menatetrenone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:94fb9178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:94fbb9a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:94fbe222-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:94fc0a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:94fc3272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:94fc5a9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:94fc83d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:94fcabee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:94fcd402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:94fcfc02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.504']} DrugCentral uuid:94fd24c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:94fd4cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:94fd74f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:94fd9cfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:94fdc56a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:94fdedb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:94fe16be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:94fe3f54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:94fe689e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:94fe90bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:94feb8a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UDY8 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Enzyme (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:94fee256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:94ff0646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:94ff2e6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:94ff57cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:94ff80ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:94ffa934-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:94ffd134-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:94fff4d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:95001eaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:9500429a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:95006acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:950092ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9500bbf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9500ef7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9500ef7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9500ef7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9500ef7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9501444c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9501444c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9501444c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9501444c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95018ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:9501b878-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephentermine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:95020008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9502832a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9502832a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9502832a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9502bb4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9502df3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:9503032c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:950327f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:95034c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:9503710e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:950394f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:9503b8d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9503dde2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.821']} DrugCentral uuid:95040e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:95040e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:95040e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:95044d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:95044d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:95044d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:95048ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:95048ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:95048ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:9504cb6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9504cb6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:9504cb6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:950503b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meproscillarin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:95052896-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:95055122-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:95057954-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9505a32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:9505cb70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:9505f384-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:95061bc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:95064460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:95066c92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.276']} DrugCentral uuid:950694ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.955']} DrugCentral uuid:9506bcec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:9506e578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:95070d8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:950735c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q389T8 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:95075de6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:95078852-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:9507ac1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:9507cff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) DrugCentral uuid:9507f3d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06203 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine is inhibitor of Enzyme (Amidophosphoribosyltransferase) DrugCentral uuid:95081808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:95083d2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:95086556-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:9508890a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:9508ad2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:9508d0ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:9508f4a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:9509188e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:95093d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9509685c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:95099098-dc5e-11ec-be2c-0242ac110005 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9509b8ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XEC0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9509e246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:950a0db6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:950a31a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:950a5604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:950a7a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:950aa294-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:950acac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:950af2f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WU19 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Hydroxyacid oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:950b1cba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:950b455a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.724']} DrugCentral uuid:950b6da0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:950b95dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:950bbee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:950be708-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:950c0f30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:950c3758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:950c5fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.744']} DrugCentral uuid:950c87f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:950cb00c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:950cd820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:950d01d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:950d2a00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:950d5336-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.041']} DrugCentral uuid:950d7b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.647']} DrugCentral uuid:950da3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:950dcc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:950df494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.282']} DrugCentral uuid:950e1dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:950e466a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.958']} DrugCentral uuid:950e6ec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orciprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:950e96f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orciprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:950ec07c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metaraminol is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:950ee4c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:950f0d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:950f3534-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:950f5dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:950f8606-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:950fae10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:950fd642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:950ffeba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:951026f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:95104fc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:951077f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9510a130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9510c944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.124']} DrugCentral uuid:9510f176-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.583']} DrugCentral uuid:95111994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:951142fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:95116b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9511936a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:9511bba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:9511e43c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:95120cd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:95123518-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95125d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.872']} DrugCentral uuid:951287d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9512b006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9512d842-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9513006a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:9513295a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:95135182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:951379aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9513a222-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9513ca54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9513f39e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:95141be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:951450aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:951450aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:951450aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:951450aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9514a1cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9514a1cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9514a1cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9514e182-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:95150554-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:95152d54-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.697']} DrugCentral uuid:95155554-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.401']} DrugCentral uuid:95157dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.499']} DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951662f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:951861d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:95188af8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:9518b334-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:9518d71a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9518ff56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:951928d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:951950e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:951978fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9519a136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:1727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metacycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9519ca30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:9519f262-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:951a1b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:951a43a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:951a67ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:951a8ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:951abf1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:951abf1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:951abf1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:951abf1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:951b08d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylmethadol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:951b30e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylmethadol is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:951b549a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.383']} DrugCentral uuid:951b7cc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:951ba7ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:951bd320-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:951bfda0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:951c25be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:951c4e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:951c7690-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.611']} DrugCentral uuid:951c9ed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:951cc852-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:951cf084-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:951d188e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:951d4098-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:951d7982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:951d7982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:951d7982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:951d7982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:951d7982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:951dc41e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:951dec64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:951e1504-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:951e3d36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:951e65ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:951e8e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.409']} DrugCentral uuid:951eb6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:951edf0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:951f072a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:951f30a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:951f5c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:951f86c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:951faef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:951fd77c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:95200724-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:95200724-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:95200724-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:95204e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:95204e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:95204e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:95209464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:95209464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:95209464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:9520da82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:9520da82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:9520da82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:95212190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:95212190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:95212190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:95216786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:95216786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:95216786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:9521adfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:9521adfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:9521adfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:9521f016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:9521f016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:95222ae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:95222ae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:95222ae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:95227266-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:95227266-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:95227266-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9522eac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9523a0f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9523c954-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9523f1a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:95241a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9524424e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:95246a76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9524928a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9524bc92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9524e794-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:95250fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:952537c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9525607a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:95258898-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9525b0b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9525d8de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9526016a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:95262988-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:952651ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:952679e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9526a390-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9526cbcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9526f3ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:95271c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:952744ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:95276e6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:95279688-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9527be9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9527e714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:95280f46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:952861e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:95290900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:95290900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:95293c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:95296490-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:95298cb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9529b54e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methdilazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:9529d916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07944 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin targets Enzyme (Beta-lactam-inducible penicillin-binding protein) DrugCentral uuid:9529fcca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18843 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin targets Enzyme (NH(3)-dependent NAD(+) synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:952a34b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:952a34b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:952a34b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:952a34b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:952a34b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:952a810e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:952aa936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:952ad1a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:952afa3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15101 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:952b2262-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1747 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methocarbamol is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:952b4a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:952b76b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:952b76b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:952b76b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:952bb40c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:952bb40c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:952be17a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:952c0560-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:952c2b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:952c4ee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:952c72f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:952c9b4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:952cbfe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:952ce7fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:952d0bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:952d33c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:952d5c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:952d843a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:952dac9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:952dd4b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:952dfef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.14']} DrugCentral uuid:952e2714-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:952e4f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:952e7746-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:952ea022-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:952ec82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:952ef040-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:952f18b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:952f40cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:952f69da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:952f9216-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:952fbb92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:952fe3ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:95300bf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00380 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:9530340a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:95305ce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:9530850e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9530adc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9530d5f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomepromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.237']} DrugCentral uuid:9530ffac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomepromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:953127de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:95315006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:95317838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:9531a31c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9531d580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9531d580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9531d580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:953213ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is agonist of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9532712a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:95332796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:95334fd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:953378d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:9533a108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.01']} DrugCentral uuid:9533c93a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:9533f158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:953421d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:953421d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:953421d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:953458f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:95347cb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metildigoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:9534a0d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:9534c59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:9534e96e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.282']} DrugCentral uuid:9535118c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:95353aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.672']} DrugCentral uuid:953562ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:95358aae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9535b2a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9535dae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:953603da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:95362bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15770 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9536540c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:95367c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9536a498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9536cd56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:9536f588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:95371f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:95374786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.633']} DrugCentral uuid:95376fe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9537981c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is partial agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9537c0b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9537e8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.928']} DrugCentral uuid:953810f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.678']} DrugCentral uuid:95383920-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:953861b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:953889c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9538b1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9538dae2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.033']} DrugCentral uuid:95390396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:95392baa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:953953c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:95397c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:9539a472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9539cc7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:9539f5c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:953a1e70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:953a467a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:953a6ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.58']} DrugCentral uuid:953a97ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:953ac15e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:953ae9a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:953b11cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:953b39ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:953b6258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:953b8a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:953bbe1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:953bbe1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:953bbe1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:953bbe1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:953c0bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:953c0bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:953c3ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:953c6720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:953c90ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:953cb900-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:953ce1be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:953d09f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:953d3286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:953d5aae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:953d82f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:953dabf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.615']} DrugCentral uuid:953dd47a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:953dfcc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:953e24e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:953e4d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:953e77a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:953e9b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:953ec3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:953eebb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:953f0ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1771 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:953f3b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:953f3b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:953f3b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:953f72b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:953f9b16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:953fc460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:953fec7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9540149c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:95403df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:95406622-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95408e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.663']} DrugCentral uuid:9540b672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:9540ded6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:954106e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:95412ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.213']} DrugCentral uuid:9541571c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.334']} DrugCentral uuid:9541807a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:9541a8ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:9541d0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:9541f924-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:954223c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:95424bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:95427458-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:95429d16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:9542c57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:9542eda2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:954315b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:95433e42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9543666a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:95438ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9543b6ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:9543e7e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9543e7e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9543e7e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:95442640-dc5e-11ec-be2c-0242ac110005 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:95444e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:954476cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:95449efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9544c71c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:9544ef44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:95451bfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:95454520-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metiazinic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:95456e56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metipranolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:9545923c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metipranolol is antagonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:9545b76c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene is antagonist of GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:9545db7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:9545ff56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9546277e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metochalcone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:95465064-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:954678a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:9546a0d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:9546c90e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:9546f21c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:95471a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:95474276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:95476a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:9547900a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.509']} DrugCentral uuid:9547b9e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:9547e212-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:95480a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:954832da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:95485b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:95488366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:9548aba2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9548d474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9548fc9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:954924ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:954951ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:954951ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9549980a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9549980a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9549980a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9549980a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9549980a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9549f8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9549f8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9549f8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9549f8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:954a4a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:954a4a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:954a4a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:954a91ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:954a91ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:954a91ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:954ad7ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:954ad7ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:954ad7ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:954b19fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:954b19fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:954b4fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:954b77ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone targets Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.45']} DrugCentral uuid:954ba028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:954bc4f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:954bedee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:954c168e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:954c3ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:954c67b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:954c8fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:954cb7f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:954ce050-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:954d09ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.83']} DrugCentral uuid:954d3be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:954d3be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:954d3be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:954d7a2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:954da31e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:954dcb46-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4LW95 biolink:molecularly_interacts_with DrugCentral:1790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metronidazole targets Enzyme (Thioredoxin reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:954df404-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:954e1c0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:954e4486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:954e6ca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:954e94d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.84']} DrugCentral uuid:954ebcf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07101 biolink:molecularly_interacts_with DrugCentral:1792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metirosine is inhibitor of Enzyme (Tyrosine 3-monooxygenase) DrugCentral uuid:954ee26a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:954f0d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:954f31ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:954f56aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:954f7afe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:954f9ec6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:954fc7f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:954ff024-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:955018a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:955040ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:9550691e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:95509164-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9550ba7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:9550e29a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.51']} DrugCentral uuid:95510aae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:955132ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:95515b4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62205 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:95518362-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2APX8 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9551ab58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9551d376-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9551fbee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9552242a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:95524c2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:95526fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:955299e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9552c204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9552ea0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:95531218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:95533ad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:955362fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:95538b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9553b452-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:9553dcd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:955404e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:95542cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:955456aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:95547f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9554a790-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:9554cfa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9554f862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:955521ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:955549c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02768 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:955571d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:95559a38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14778 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Membrane receptor (Interleukin-1 receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9555c22e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41222 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95560126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:95560126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:95560126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:95560126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:95560126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:95560126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:95560126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:955661b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:955689f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9556b210-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:9556db00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:95570314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.149']} DrugCentral uuid:95572b3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:955754a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:95577dee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:9557a620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9557ce3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.175']} DrugCentral uuid:9557f65c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:95581ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9558480a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:95587028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:955898a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.245']} DrugCentral uuid:9558c122-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:9558e92c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:95591140-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:95593a26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:9559626c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:95598a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.541']} DrugCentral uuid:9559b2a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:9559dc06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:955a060e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:955a2e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:955a562c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:955a7fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:955aa7da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:955acfee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:955af816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:955b2138-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:955b4a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:955b726e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:955b9aa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:955bc5b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:955bee88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:955c169c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:955c3ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:955c6714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:955c8f28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:955cb746-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:955ce04a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:955d087c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:955d30b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:955d58d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:955d8252-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:955dab4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:955dd356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:955dff66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:955dff66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:955e3e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:955e3e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:955e3e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:955e3e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:955e8f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:955e8f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:955e8f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:955ed706-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:955ed706-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:955ed706-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:955f1914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:955f1914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:955f5514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:955f5514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:955f5514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:955f9d94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:955f9d94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:955fd35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NG02 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (G-protein coupled receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:955ffbd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9560241c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95604c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:95607444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:95609cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9560c502-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9560ed02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9561152a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:95613f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:95616732-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:95618f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:9561b750-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9561dfd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:95620962-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9562319e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:956259bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:95628266-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07652 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent R-type calcium channel subunit alpha-1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9562aa84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9562d2ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9562fbc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15390 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:956324c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:95634cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:956374dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AIC4 biolink:molecularly_interacts_with DrugCentral:1798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 micafungin targets Unclassified (Beta-1,3-glucan synthase) DrugCentral uuid:95639926-dc5e-11ec-be2c-0242ac110005 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:1798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 micafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) DrugCentral uuid:9563bce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.715']} DrugCentral uuid:9563e4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.137']} DrugCentral uuid:95640d2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.588']} DrugCentral uuid:956435fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:95645e2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:9564864c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.505']} DrugCentral uuid:9564ae74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9564d764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:9564ffa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:956528d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:95654c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:95657516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:95659d2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.535']} DrugCentral uuid:9565c534-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.183']} DrugCentral uuid:9565ee56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:9566173c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.452']} DrugCentral uuid:95663f64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.555']} DrugCentral uuid:9566678c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:95668fbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:9566ba34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.964']} DrugCentral uuid:9566e4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:95670cdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:956734e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:95675d54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.175']} DrugCentral uuid:956785fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:9567ae26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.386']} DrugCentral uuid:9567d64e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.869']} DrugCentral uuid:9567ff16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9568270c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.136']} DrugCentral uuid:95684f20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.799']} DrugCentral uuid:956877fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.271']} DrugCentral uuid:9568a330-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:9568cb94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:9568f3e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:9569187e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.923']} DrugCentral uuid:9569409c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:95696892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.729']} DrugCentral uuid:9569909c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:9569b8e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9569e0f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.534']} DrugCentral uuid:956a0a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:956a3222-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:956a5afe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:956a831c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:956aab30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.381']} DrugCentral uuid:956ad33a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.562']} DrugCentral uuid:956afcf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:956b251a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:956b4d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:956b7542-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:956b9dba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:956bc5e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:956bee14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.029']} DrugCentral uuid:956c1650-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.922']} DrugCentral uuid:956c408a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.674']} DrugCentral uuid:956c68bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.792']} DrugCentral uuid:956c90da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.692']} DrugCentral uuid:956cb8ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:956ce1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:956d09f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:956d327e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:956d5af6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:956d830a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:956dab28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:956dd346-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:956dfd12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:956e2530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:956e4d44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:956e7558-dc5e-11ec-be2c-0242ac110005 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:956e9e02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:956ec60c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6']} DrugCentral uuid:956eee34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.353']} DrugCentral uuid:956f165c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:956f3ede-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:956f6eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:956f6eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:956f6eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:956fb4b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:956fb4b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:956fb4b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:956ffdec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:956ffdec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:956ffdec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9570759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:95714e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:95714e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:95714e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:95719440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:95719440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:95719440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:9571dc66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9571dc66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9571dc66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95722284-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:95722284-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:95722284-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:95726956-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95726956-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95726956-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9572a8f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midodrine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:9572ccd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midodrine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:9572f556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.001']} DrugCentral uuid:95731d88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.957']} DrugCentral uuid:9573459c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:95736dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.918']} DrugCentral uuid:95739858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9573c1b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9573e9d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:957412a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:95743ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:957462e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:95748b1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9574b3dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9574dc22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:95750454-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.081']} DrugCentral uuid:95752c68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.255']} DrugCentral uuid:95755594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.256']} DrugCentral uuid:95757db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.374']} DrugCentral uuid:9575a5e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:9575cdf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:9575f6c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95761ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1Q298 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9576472e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1U3 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:95767050-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:957698dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:9576bcb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:9576e4e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:95770cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:957737d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:957761e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:957789f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9577b1fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9577dab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q58D55 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:957802da-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0HJB3 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Alpha-mannosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:95782b16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56526 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:95785334-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:95787bac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:9578a3d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9578cbe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9578f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q69ZF3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:95791e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:95794672-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:95796efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:957997a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9579c0e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70699 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9579e906-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5THE3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:957a1110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9LGC6 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Putative alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:957a3992-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70282 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Trehalase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:957a6192-dc5e-11ec-be2c-0242ac110005 UniProtKB:I3LIR5 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:957a8aa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88693 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:957ab2c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:957adc76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:957b04c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:957b2ce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:957b5502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:957b7e56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:957ba67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:957bce9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:957bf6ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:957c1f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:957c476e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:957c6f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:957c97a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:957cc0fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:957ce908-dc5e-11ec-be2c-0242ac110005 UniProtKB:O89085 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:957d14f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:957d14f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:957d54c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:957d54c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:957d54c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:957d54c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:957d9e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miltefosine targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:957dc62a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miltefosine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:957dee98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:957e135a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:957e3b6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08543 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:957e6382-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:957e8eca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:957eb9b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:957ee1d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:957f09ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:957f33ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:957f5bde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.638']} DrugCentral uuid:957f83f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z7H2 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Unclassified (30S ribosomal protein S4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['6']} DrugCentral uuid:957facf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z8T8 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Unclassified (30S ribosomal protein S9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['5.756']} DrugCentral uuid:957fd51e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:95800110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:95800110-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:95802e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:95805778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:95807fbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9580a7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:9580d004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9580f930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:9581216c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9581499e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:958171e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:95819a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:9581c298-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9581ead4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:95821400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:958239da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:95825dc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9582861a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9582ae4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:9582d6e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9582ff14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:9583273c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:95834f64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95837f70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:95837f70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:95837f70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9583bdfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9583e618-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:95840f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:95843794-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:958463a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:958463a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:95849720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitomycin targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9584c092-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:9584e8ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:9585110a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:95853996-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.512']} DrugCentral uuid:958561c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.186']} DrugCentral uuid:95858a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9585b218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:9585dd88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) DrugCentral uuid:95860178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10109 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Unclassified (Adrenodoxin, mitochondrial) DrugCentral uuid:95862554-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:95864926-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:95867194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.841']} DrugCentral uuid:958699b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.306']} DrugCentral uuid:9586c1c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.729']} DrugCentral uuid:9586ea02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.744']} DrugCentral uuid:95871266-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:95873a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.047']} DrugCentral uuid:9587628e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:95878674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC90', 'has_quantitative_value': ['5.959']} DrugCentral uuid:9587b036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.287']} DrugCentral uuid:9587d854-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kact', 'has_quantitative_value': ['5.155']} DrugCentral uuid:9588007c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:95882890-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:95885176-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:95887994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:9588a1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:9588c9da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9588f248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:95891a48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:95894248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95896a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:958995d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:9589bf02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9589e716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:958a0f8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:958a3784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:958a5fa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:958a88c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:958ab4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:958ab4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:958ab4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:958aebf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:958b13f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:958b37d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:958b626c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:958b8a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:958bb32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:958bdb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:958c03de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:958c2c38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:958c544c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:958c7cc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:958ca4f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:958ccd32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:958cf0f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.396']} DrugCentral uuid:958d1a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:958d4104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:958d6b20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:958d942e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moexipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:958dbc9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:958de4ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:958e0cf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:958e3514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:958e5d8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.157']} DrugCentral uuid:958e85a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:958eadbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:958ed5f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.421']} DrugCentral uuid:958eff94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:958f27b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:958f4fda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:958f780c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:958fa098-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:958fc8b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.254']} DrugCentral uuid:958ff0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95901938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:959042d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:95906af0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.763']} DrugCentral uuid:95909322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9590bb40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9590e764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:95910f82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:959137c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molsidomine targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:95916040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:95918958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9591b194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:9591d99e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.429']} DrugCentral uuid:9592020c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.992']} DrugCentral uuid:95922a48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.414']} DrugCentral uuid:95925270-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:959276ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.311']} DrugCentral uuid:9592a392-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9592cbce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:9592f41e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.574']} DrugCentral uuid:95931c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:959344dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:95936d22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:95939568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.853']} DrugCentral uuid:9593bd9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.495']} DrugCentral uuid:9593e626-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:95940e62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:95943676-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:95945e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.958']} DrugCentral uuid:95948856-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:9594b088-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9594d892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.328']} DrugCentral uuid:959500ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.495']} DrugCentral uuid:95952932-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:9595515a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.817']} DrugCentral uuid:95957a5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9595a2fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:9595cb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.895']} DrugCentral uuid:9595f358-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:95961cc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9596466e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:95966e82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:959696aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:9596bedc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.134']} DrugCentral uuid:9596e786-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moracizine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:95970b6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.86']} DrugCentral uuid:95973394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:95975bbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9597843e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9597ac48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:9597d45c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9597fc7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9598260a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:95984e3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:959876f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:95989f18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9598c7ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9598efd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:959917f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47748 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:95994bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:95994bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:95994bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:95994bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9599a5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:9599a5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:9599a5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:9599a5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:9599a5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:959a0632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:959a0632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:959a0632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:959a0632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:959a5006-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q98UH1 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu opioid receptor-like OR2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:959a7824-dc5e-11ec-be2c-0242ac110005 UniProtKB:B3DH72 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor, delta 1b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:959aa0a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O57585 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor homologue) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:959ac8d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:959af0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:959b1a54-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:959b42ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:959b6b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.891']} DrugCentral uuid:959b9330-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:959bbc2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:959be696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.694']} DrugCentral uuid:959c0ed2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.725']} DrugCentral uuid:959c36f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.683']} DrugCentral uuid:959c5f86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:959c87a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:959cb0bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:959cd8c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:959d0134-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:959d2cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:959d2cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:959d6070-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:959d888e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.938']} DrugCentral uuid:959db28c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.716']} DrugCentral uuid:959ddab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.637']} DrugCentral uuid:959e02e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:959e26a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:959e4f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:959e7b2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:959e7b2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:959ead22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:959ead22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:959ee0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:959f08e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:959f310c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:959f593e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:959f82b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:959faac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:959fd300-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine is agonist of Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:959ffb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00956 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:95a02396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41252 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:95a04ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41972 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:95a06f86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99YW3 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:95a0943e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56690 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:95a0bdd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:95a0e61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:95a10e46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:95a1366e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:95a169cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95a169cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95a19d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5KP44 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Unclassified (Inosine-5'-monophosphate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:95a1c548-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:95a1edde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:95a215e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:95a23dfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:95a2662e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:95a28a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.34']} DrugCentral uuid:95a2b246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.732']} DrugCentral uuid:95a2da6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:95a30278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.001']} DrugCentral uuid:95a32ce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:95a35520-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:95a37d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95a3a570-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:95a3cdc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:95a3f5e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:95a41df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:95a445f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:95a46f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:95a49840-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00736 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Complement C1r subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95a4c054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09871 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Complement C1s subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:95a4e9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:95a51400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:95a53c14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:95a56414-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:95a58c78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:95a5b482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:95a5dca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:95a604be-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:95a62da4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafarelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.699']} DrugCentral uuid:95a655a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:95a689d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:95a689d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:95a689d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:95a689d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:95a689d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:95a6d77c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftidrofuryl targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:95a701ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:95a729d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:95a751e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (Squalene monooxygenase) DrugCentral uuid:95a77614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:95a799dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:95a7c1f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O07855 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (Dehydrosqualene desaturase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:95a7ea04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:95a81a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:95a81a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:95a81a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:95a861d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:95a861d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:95a861d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:95a8a17e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:95a8c99c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:95a8f1f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:95a91a1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:95a942c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:95a96afa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:95a99340-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:95a9bb4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:95a9e804-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:95a9e804-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:95aa159a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.53']} DrugCentral uuid:95aa3de0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:95aa67e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:95aa933a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:95aabd88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:95aae5ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:95ab0e32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:95ab365a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:95ab5e46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:95ab8786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:95abb008-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:95abd916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:95ac0cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:95ac0cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:95ac0cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:95ac0cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:95ac63f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:95ac63f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:95ac63f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:95ac63f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:95acad82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:95acd654-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:95acfe7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:95ad2686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:95ad4ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:95ad771c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:95ad9f30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:95adc758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:95adef58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:95ae18fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:95ae4430-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:95ae6cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:95ae94f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:95aebdc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:95aee5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.98']} DrugCentral uuid:95af1914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:95af1914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:95af1914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:95af1914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:95af645a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:95af8804-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:95afb02c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95afd84a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:95b002a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.678']} DrugCentral uuid:95b02ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:95b05310-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:95b07818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:95b0a0f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95b0c9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:95b0f22a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:95b11ab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:95b142de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone phenpropionate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:95b16af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone phenpropionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:95b1931a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:95b1bc14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:95b1e450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:95b20c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:95b2345a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:95b25cdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:95b284dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:95b2acf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:95b2d504-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:95b30222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:95b30222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:95b33558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:95b35da8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:95b385da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.796']} DrugCentral uuid:95b3aeca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:95b3d6fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:95b3ff24-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:95b42bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:95b42bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:95b4632e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:95b4632e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:95b4968c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:95b4bebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:95b4e740-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:95b50f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:95b53786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:95b56076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nedocromil targets GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:95b58664-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nedocromil is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:95b5ae64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:95b5d696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:95b600bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.699']} DrugCentral uuid:95b628f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:95b65120-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:95b67966-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:95b6a2ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.143']} DrugCentral uuid:95b6caec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.789']} DrugCentral uuid:95b6f31e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.635']} DrugCentral uuid:95b71bdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:95b744f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:95b76d12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:95b794f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:95b7bcfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:95b7e580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:95b80db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:95b835d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:95b85de4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:95b886a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:95b8aea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:95b8d6ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:95b8feb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:95b92490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:95b94ca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:95b974a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:95b99cc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:95b9c53a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:95b9ed44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:95ba1562-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:95ba3d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:95ba663e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:95ba8f06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95bab6f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.057']} DrugCentral uuid:95badff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.209']} DrugCentral uuid:95bb09ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.592']} DrugCentral uuid:95bb321c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.909']} DrugCentral uuid:95bb5a26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.078']} DrugCentral uuid:95bb8294-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.842']} DrugCentral uuid:95bbaa94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.632']} DrugCentral uuid:95bbd2bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.255']} DrugCentral uuid:95bbfbde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:95bc2032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.101']} DrugCentral uuid:95bc4904-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.098']} DrugCentral uuid:95bc7122-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.676']} DrugCentral uuid:95bc9940-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.648']} DrugCentral uuid:95bcc244-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.739']} DrugCentral uuid:95bcea4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:95bd126c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.615']} DrugCentral uuid:95bd3a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:95bd62e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.236']} DrugCentral uuid:95bd8b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:95bdb3ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:95bddbf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:95be04ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:95be2cec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:95be550a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:95be7d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:95bea744-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:95becf80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:95bef794-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:95bf1fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:95bf4834-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:95bf6bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08312 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase alpha subunit) DrugCentral uuid:95bf8f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07395 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase beta subunit) DrugCentral uuid:95bfb364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95bfdc2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:95c0044a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:95c02c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:95c05486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:95c07d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:95c0a56c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:95c0cd6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:95c0f580-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:95c11e20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:95c14620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:95c16e2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:95c19ada-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:95c19ada-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:95c1d31a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:95c1d31a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:95c206b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepinalone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:95c22f54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nesiritide is agonist of Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:95c25506-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:95c27dec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:95c2a60a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:95c2ceaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95c2f6be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:95c31edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 2) DrugCentral uuid:95c34312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 3) DrugCentral uuid:95c36752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:95c38b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:95c3aece-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:95c3d6ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:95c3ff14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:95c42836-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53686 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase HST2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:95c45040-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NTG7 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase sirtuin 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:95c47868-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:95c4a0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8I6E4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Unclassified (Putative silent information regulator 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:95c4c8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:95c4f0fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:95c51908-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:95c541da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:95c569ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:95c58db6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:95c5b5c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95c5dee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.553']} DrugCentral uuid:95c609b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:95c6323e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:95c65a5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:95c683c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:95c6abf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54698 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:95c6d3f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:95c70394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:95c70394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:95c70394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:95c74b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:95c74b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:95c74b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:95c79142-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:95c79142-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:95c79142-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:95c7d472-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:95c7d472-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:95c801f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:95c829fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15385 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:95c852e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:95c87aee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:95c8a2f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:95c8caf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95c8f35c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:95c91b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95c9437a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:95c96b8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:95c99546-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:95c9be2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:95c9e640-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:95ca0e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:95ca373a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:95ca5f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:95ca874e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:95caaf76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:95cad7c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:95caffbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:95cb27da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:95cb4fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:95cb7aa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:95cba2d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:95cbcad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:95cbf35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:95cc1b72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:95cc43d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:95cc6bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:95cc95c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:95ccbde8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43144 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:95cce5fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit beta-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:95cd0e2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04757 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:95cd3764-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12389 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:95cd5f82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:95cd8886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:95cdb086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21687 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Enzyme (Lycopene cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:95cdd944-dc5e-11ec-be2c-0242ac110005 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:95ce0158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25162 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit beta-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:95ce2976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09482 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:95ce51a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70174 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:95ce7dd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95ce7dd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95ceb4f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:95ceb4f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:95ceec08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:95ceec08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:95cf256a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:95cf256a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:95cf5db4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95cf5db4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95cf94c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:95cf94c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95cff652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:95d0a80e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95d0a80e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:95d0e238-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:95d0e238-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:95d11c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:95d11c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:95d1533a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:95d1533a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:95d18b16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:95d18b16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:95d1cd60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:95d1cd60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:95d1cd60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:95d1cd60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:95d1cd60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:95d22e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:95d22e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:95d22e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:95d22e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:95d28458-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:95d28458-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:95d28458-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:95d28458-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:95d2d566-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:95d2d566-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:95d31724-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:95d31724-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:95d31724-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:95d31724-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:95d3703e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:95d3703e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:95d3703e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:95d3703e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:95d3703e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:95d3c48a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:95d3ed16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:95d41534-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95d43d3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:95d4657a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95d48fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.089']} DrugCentral uuid:95d4b7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:95d4e11c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:95d50926-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:95d53194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:95d559d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.019']} DrugCentral uuid:95d58202-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.348']} DrugCentral uuid:95d5aa2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:95d5d37e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:95d5fb92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:95d6239c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:95d64bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:95d6764e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:95d69e80-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.672']} DrugCentral uuid:95d6c69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:95d6eeb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:95d71716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95d73f34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:95d76752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.355']} DrugCentral uuid:95d7902e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:95d7b838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16389 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95d7e060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:95d8086a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.731']} DrugCentral uuid:95d83218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:95d85b6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95d883a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:95d8ac98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.821']} DrugCentral uuid:95d8d51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:95d8fd42-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:95d92588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:95d94dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:95d976a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:95d99ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:95d9c718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:95d9ef4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:95da1a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35505 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:95da4bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:95da4bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:95da4bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:95da9314-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:95da9314-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:95da9314-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:95dad1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:95daf9da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:95db21ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:95db4ab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:95db72ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95db9b92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:95dbc3d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:95dbeee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95dc19b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:95dc41f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:95dc6a18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:95dc9286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.037']} DrugCentral uuid:95dcba9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.973']} DrugCentral uuid:95dce2c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:95dd0b58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:95dd3380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51800 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Ka) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95dd5b9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:95dd8394-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:95ddacde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51801 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Kb) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95ddd7fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.55']} DrugCentral uuid:95de0210-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifuroxazide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:95de2a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:95de52a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:95de7ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:95dea2f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:95decb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:95def3d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:95df1bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95df4454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:95df6c7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:95df963e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:95dfbe8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.83']} DrugCentral uuid:95dfe6ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:95e010aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:95e0392c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.33']} DrugCentral uuid:95e06154-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:95e08986-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:95e0b19a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:95e0da4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:95e10276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:95e12a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:95e153b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:95e17e72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:95e1a690-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:95e1ce9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.387']} DrugCentral uuid:95e1f708-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:95e21f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:95e24730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:95e26f4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:95e29834-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:95e2c03e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:95e2e85c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:95e31084-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:95e33ac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:95e36322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:95e38b40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:95e3b368-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:95e3dc08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.096']} DrugCentral uuid:95e40516-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:95e42d3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:95e45552-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:95e47e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:95e4a642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:95e4ce6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.141']} DrugCentral uuid:95e4f67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:95e51fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:95e547c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:95e56ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:95e59872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:95e5c0a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:95e5e8c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:95e61216-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:95e63a8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:95e662b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:95e68ac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:95e6b2e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:95e6dc1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:95e70450-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:95e72c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:95e75496-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:95e77d54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:95e7a586-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:95e7cd9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:95e7f6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:95e81f5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:95e8477a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95e86f98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:95e8984c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:95e8c2c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:95e8eafe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:95e9131c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:95e93b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:95e96448-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:95e98c5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:95e9b47a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:95e9e10c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:95e9e10c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:95ea144c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:95ea3c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:95ea601e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:95ea854e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:95eaad6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:95eaad6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:95eadaf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:95eb032a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:95eb2bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.927']} DrugCentral uuid:95eb542e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:95eb7c42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:95eba460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:95ebced6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.632']} DrugCentral uuid:95ebf6f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:95ec1f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:95ec474e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2A865 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:95ec7124-dc5e-11ec-be2c-0242ac110005 UniProtKB:L8I2E6 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Dipeptidyl peptidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:95ec9960-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:95ecc1a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:95ecea64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:95ed1296-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:95ed3ac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:95ed62dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:95ed8708-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:95edaf26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:95edd2ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:95edf6c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95ee1ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:95ee4a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95ee75b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:95ee9eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:95eec834-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95eef066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95ef187a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:95ef40ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:95ef6938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:95ef916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:95efba78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:95efe282-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:95f00762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.395']} DrugCentral uuid:95f02fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:95f057ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:95f07bd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:95f0a4b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95f0d4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:95f0d4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:95f0d4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:95f11314-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:95f13ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99246 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:95f164d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:95f18cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q968X7 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate dehydrogenase [NADP(+)]) DrugCentral uuid:95f1b0d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q24982 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate:ferredoxin oxidoreductase) DrugCentral uuid:95f1d54c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0P8E1 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide targets Enzyme (Pyruvate-flavodoxin oxidoreductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:95f1fd92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32754 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone is inhibitor of Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:95f225c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02110 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone targets Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:95f24dec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32755 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone targets Unclassified (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:95f27e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:95f27e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:95f27e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:95f2cf74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95f2cf74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95f2cf74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95f2cf74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95f2cf74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95f2cf74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:95f3309a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:95f3589a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:95f380c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:95f3aa3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:95f3cfb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.921']} DrugCentral uuid:95f3f7f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:95f42022-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:95f448ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.056']} DrugCentral uuid:95f470cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:95f498fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95f4c108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:95f4ea16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:95f51234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95f53a48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95f56270-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21556 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:95f593bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:95f593bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:95f593bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:95f5d21e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:95f605c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f605c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f605c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f605c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f64988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurantoin targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:95f66d5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurantoin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:95f69596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurazone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:95f6b9b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:1950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurazone targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:95f6e1d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:95f7112e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f7112e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f7112e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f7112e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:95f753b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:95f77c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:95f7a454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:95f7cc54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:95f7f512-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:95f81d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:95f84544-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nizatidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:95f86d80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nizatidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.251']} DrugCentral uuid:95f895ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:95f8be16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:95f8e62a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:95f90e3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:95f9380a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:95f96028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.947']} DrugCentral uuid:95f98846-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.963']} DrugCentral uuid:95f9b05a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:95f9d8fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:95fa021c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:95fa2a44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:95fa5686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:95fa5686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:95fa89e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norelgestromin is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:95faae38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:95fad66a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:95faff5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:95fb2778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:95fb4fc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:95fb794e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:95fba1da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:95fbc9ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.367']} DrugCentral uuid:95fbf23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:95fc1a52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:95fc4324-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:95fc6b74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:95fc9392-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:95fcbba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:95fce5c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:95fd0dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:95fd361c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:95fd5e1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:95fd86c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:95fdaee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:95fdd72a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:95fe08a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:95fe08a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:95fe08a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:95fe4ed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:95fe4ed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:95fe4ed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:95fea15a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95fea15a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95fea15a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95fea15a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95fea15a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95fea15a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:95ff0910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95ff0910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95ff0910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:95ff47b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01337 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:95ff6fe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:95ff9808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:95ffc026-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:95ffe8ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.636']} DrugCentral uuid:96001238-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:96003a56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:96006260-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:96008c0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9600b49a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.914']} DrugCentral uuid:9600e186-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:9600e186-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:96011520-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:96013d3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.533']} DrugCentral uuid:9601657a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:96018da2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9601b656-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:9601de6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:96020674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:96022e9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:960258c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:96028194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethynodrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:9602a552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethynodrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:9602cd52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9602f5c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:96031dc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:960345de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:96036de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:960396a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9603beb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9603e6ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:96040eec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:96043a2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:960464a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:96048dae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9604eef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9605be22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.01']} DrugCentral uuid:9605e668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:96060d50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9606358c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:96065daa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:960685dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9606aecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:9606d726-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:960700d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.36']} DrugCentral uuid:9607297e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:960751b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:960779f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:9607a20a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9607cb40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:9607f368-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:96081ba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:960843c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:96086c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.033']} DrugCentral uuid:96089494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.639']} DrugCentral uuid:9608bcda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:9608e4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:96090d8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:960935b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:96095dd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:960985d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:9609b036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:9609d84a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.921']} DrugCentral uuid:960a0068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6.225']} DrugCentral uuid:960a29e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:960a52ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:960a7ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:960aa2e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:960acb06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:960af4b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:960b1cd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:960b450e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:960b6de0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78508 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:960b9662-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.087']} DrugCentral uuid:960bbe80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:960be694-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:960c0f66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:960c378e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:960c5f98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:960c8838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A4L9 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:960cb09c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7X1P7 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (ParE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:960cd8b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3SLN2 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:960d04ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:960d04ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:960d3c06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:960d3c06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:960d6ad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C559 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:960d9318-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A0K8 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:960dbb4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0QNE0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:960de41c-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3SLN3 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:960e13f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:960e13f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:960e13f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:960e5230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:960e7abc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.699']} DrugCentral uuid:960ea3de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:960ecc2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:960ef456-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:960f1d82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:960f45dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:960f6e22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.98']} DrugCentral uuid:960f964a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:960fc03e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:960fe88e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:961010d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08858 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:96103910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:9610617e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9610899c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:9610b1e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9610d9f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:9610ff08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9611271c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:961188a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:96125876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:96128080-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9612a86c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9612d170-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9612f9ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:961321ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:961349fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.492']} DrugCentral uuid:961372ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:96139af6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9613c2f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9613eb1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:961414c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:96143d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:96146530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:96148d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:9614b9ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:9614e3e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:96150d0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:961535e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:96155e2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:9615862c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:9615ae54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.506']} DrugCentral uuid:9615d6cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:9615fef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.136']} DrugCentral uuid:96162726-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.682']} DrugCentral uuid:96164f4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:9616791a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:9616a160-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.233']} DrugCentral uuid:9616c97e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:9616f1a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:96171a6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:961742a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:96176ad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:961792f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:9617bb86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.916']} DrugCentral uuid:9617e3ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:96180bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96183426-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.558']} DrugCentral uuid:96185ec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:96188700-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:9618af46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9618d746-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:96190112-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:96192944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:96195180-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:96197a2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9619a252-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9619ca7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9619f2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:961a1d40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:961a45f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:961a6e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:961a9676-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:961abf34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:961aeee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:961aeee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:961aeee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:961b34d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:961b34d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:961b34d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:961b73a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:961b9ba2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:961bc456-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmesartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:961bed6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmesartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:961c1762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olopatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.284']} DrugCentral uuid:961c3fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olopatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:961c6bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:961c6bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:961c9ade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:961cbece-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:961ce66a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:961ce66a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:961d1400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:961d3c96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:961d64c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:961d8cc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:961db4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:961dddae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:961e05b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.31']} DrugCentral uuid:961e2dcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.051']} DrugCentral uuid:961e55d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:961e7e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:961ea69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:961eceb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:961efb30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:961efb30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:961f3352-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:961f3352-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:961f669c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:961f8eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:961fb782-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:961fe388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:961fe388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:962016aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:9620406c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:9620688a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.678']} DrugCentral uuid:962090a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9620b8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:9620e148-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:96210970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:962131a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:962159ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:962183e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9621ac72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9621d472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9621fc9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9622254e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:96224d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:962275b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96229dbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9622c620-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9622ee20-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:962319f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:962319f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:96235248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:96235248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:96238d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:96238d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:96238d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9623d02e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9623d02e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:962403e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:96242c04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9624544a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:96247e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9624a684-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9624ced4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:9624f6fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:96251fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4D2 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9625480a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:96257032-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NCG7 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9625983c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95870 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Abhydrolase domain-containing protein 16A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9625c096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N2K0 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9625e896-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13093 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Platelet-activating factor acetylhydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:962610aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00591 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:962638aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BV23 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:96266168-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6WQJ1 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:96268990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:9626b212-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11150 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Hepatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9626da4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5X9 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Endothelial lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:96270488-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.9']} DrugCentral uuid:96272ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07098 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat is inhibitor of Enzyme (Gastric triacylglycerol lipase) DrugCentral uuid:96275082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:9627788c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:9627a1fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:9627ca1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.614']} DrugCentral uuid:9627f24e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:96281a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:9628435c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:96286b8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:962893c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:9628bcec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:9628e604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:96290e2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.165']} DrugCentral uuid:9629365e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:96295ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.873']} DrugCentral uuid:962986fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:9629af12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9629d73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:962a0002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.889']} DrugCentral uuid:962a2820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:962a5188-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.764']} DrugCentral uuid:962a79a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:962aa2d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:962acadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:962af2f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:962b3256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:962b3256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:962b3256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:962b3256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:962b3256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:962b3256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:962b3256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:962b9dfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06818 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.83']} DrugCentral uuid:962bc680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:962bef52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:962c178e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:962c3fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:962c6928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:962c9178-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:962cb9a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:962ce1d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:962d0a68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:962d329a-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:962d5ad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:962d82d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:962dab8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:962dd394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:962dfbc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:962e23e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.96']} DrugCentral uuid:962e4e64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:962e774a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11172 biolink:molecularly_interacts_with DrugCentral:2002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oteracil is inhibitor of Enzyme (Uridine 5'-monophosphate synthase) DrugCentral uuid:962e9b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.169']} DrugCentral uuid:962ec326-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.009']} DrugCentral uuid:962eeba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:962f107e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:962f389c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:962f60b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:962f8964-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:962fae4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:962fe5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:962fe5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:962fe5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:962fe5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:962fe5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:963032e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:96305af6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:963086fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:963086fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9630ba96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:9630de72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:963106ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:96312ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:96315334-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:96317c06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9631a406-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9631cc42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:9631f528-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:96321d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.148']} DrugCentral uuid:96324550-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:96326d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:963295fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9632befe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:9632ef0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9632ef0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9632ef0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:96332e2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxcarbazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9633521a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:96337600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:963399fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9633c3bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9633ef0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:96341a1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:96344378-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.991']} DrugCentral uuid:96346bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.589']} DrugCentral uuid:96349440-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:9634bd9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:9634e5e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:96350ee8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:96353738-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:96355f56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.168']} DrugCentral uuid:96358792-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:9635b186-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:9635d9ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:963601d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:96362a44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:9636528a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:96367bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:9636a406-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:9636cd6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9636f596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96371daa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:963745fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:96376ecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:96379708-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9637bf30-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9637e744-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:96380ff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:96383820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9638608e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:963888c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.493']} DrugCentral uuid:9638b50c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9638dd2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:9639055c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:96392d84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.111']} DrugCentral uuid:96395688-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:96397eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:9639a6ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9639cf14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9639f7aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:963a1fc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:963a47e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:963a71b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:963a99f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:963ac356-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:963aeb88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.162']} DrugCentral uuid:963b1478-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.041']} DrugCentral uuid:963b3cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:963b64f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:963b8d18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:963bb5ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:963bddea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:963c0626-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:963c2e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:963c5e96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:963c5e96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:963c5e96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:963ca4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:963ca4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:963ca4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:963ce438-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:963d0f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:963d3726-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:963d5b02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:963d801e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:963da850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:963dd096-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:963df8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:963e2258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:963e4a9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:963e72e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:963e9b2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:963ec406-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:963eec38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:963f1474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:963f4818-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:963f4818-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:963f4818-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:963f4818-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:963f9606-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:963f9606-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:963fca68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:963fee94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:96401658-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:96401658-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:964043da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:96406bf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:96409092-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:9640b464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:9640dc82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2041 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:9641005e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2041 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:964124d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:96414ce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:964174e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:96419cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9641c57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01178 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets Secreted (Oxytocin-neurophysin 1) DrugCentral uuid:9641ea32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:96421250-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:96423a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:964263ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:96428ed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49430 biolink:molecularly_interacts_with DrugCentral:2043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9642b8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9642e14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:96430a0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:96433234-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Bile salt export pump) DrugCentral uuid:964355fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:964379c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9643a2b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.621']} DrugCentral uuid:9643cac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.954']} DrugCentral uuid:9643f2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.643']} DrugCentral uuid:96441b04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:964444ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.794']} DrugCentral uuid:96446e2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:96449656-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9644be6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13509 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Structural (Tubulin beta-3 chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9644e73c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:96452dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9645b1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9645d9ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9646022a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:96462dae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol is agonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:964656b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:964682c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:964682c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:9646b6a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamabrom targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:9646deca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:964706e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:96472efc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07010 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:96475774-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:96477f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9647a7b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:9647cfc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9647fb34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q81VW8 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:96482546-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:96484d50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WNC6 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) DrugCentral uuid:96487122-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.92']} DrugCentral uuid:96489d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:96489d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:9648d2ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:9648d2ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:9648d2ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:964916d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:964916d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:964955ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:964955ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:964955ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:964955ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9649a02e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:9649c5ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9649ede0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:964a15fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:964a3e1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:964a668a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:964a9290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:964a9290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:964ac012-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:964aec68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:964aec68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:964b1f8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:964b4794-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:964b6f94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:964b955a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:964bbd82-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:964be582-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:964c0d82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.118']} DrugCentral uuid:964c36ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:964c5ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:964c871c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:964caf30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:964cd7da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:964cfff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:964d280c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:964d502a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:964d7ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QYJ6 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:964daa5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:964daa5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:964daa5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:964dec74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:964dec74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:964e27a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:964e27a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:964e27a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:964e6604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:964e8e86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:964ebeb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:964ebeb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:964ebeb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:964ef75e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.854']} DrugCentral uuid:964f1f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:964f48ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:964f7224-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:964f9a1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:964fc242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:964feab0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:965012ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paricalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:96503ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:96506300-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:96508b64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.068']} DrugCentral uuid:9650b3aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:9650dbc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.398']} DrugCentral uuid:9651054e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.52']} DrugCentral uuid:96512f6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:96515788-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:96517f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:9651a83c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9651d046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:9651f86e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:96522078-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:96524904-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:965270f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:96529904-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9652c104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9652e9f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:965311f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:96533a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9653633e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:96538bb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.36']} DrugCentral uuid:9653b3de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9653dc06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:9654042e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:96542d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:96545cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:96545cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:96545cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9654a442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9654a442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9654a442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9654e920-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:9655113e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:96553952-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21146 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:965561e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:965589de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:9655b1de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.097']} DrugCentral uuid:9655d9d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:96560242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.468']} DrugCentral uuid:96562a6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:9656527e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:96567646-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9656a1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Serine hydroxymethyltransferase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9656ca60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9656f274-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:96571bb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:965743d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:96576bdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:965793dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9657bc4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9657e45e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:96580c7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9658347c-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:96585e2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:E2QDN0 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:96588940-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.86']} DrugCentral uuid:9658b15e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:9658d972-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64737 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:96590208-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22102 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:96592a30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:96595258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:96597a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9659a302-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9659cb0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02763 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets Secreted (Alpha-1-acid glycoprotein 1) DrugCentral uuid:9659eeca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:965a1814-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:965a3d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:965a6594-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:965a8da8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:965ab5da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:965ade7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:965b06b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:965b2fc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:965b57f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:965b8064-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:965ba882-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:965bd0a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:965bf8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:965c2226-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:965c4a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:965c728a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:965c9b2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:965cc366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:965ceb98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:965d13b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:965d3c56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:965d6474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:965d8c9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:965db4c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:965def02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:965def02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:965def02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:965def02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:965def02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:965e481c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:2081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penicillamine targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:965e708a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:965e9434-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:965ebc66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:965efc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965efc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965efc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965efc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965efc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965efc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965efc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965f5c02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:965f8420-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:965fc19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965fc19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965fc19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965fc19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965fc19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965fc19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:965fc19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9660201a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:966048d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:966070f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:96609914-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9660c13c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.287']} DrugCentral uuid:9660e9d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:96611204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:96613a40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9661625e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:96618c98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:9661b786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.295']} DrugCentral uuid:9661e27e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:96620cae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.683']} DrugCentral uuid:96623530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:96625d6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:9662859e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.101']} DrugCentral uuid:9662adbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9662d62a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9662fe5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:96632670-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:96634e8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04271 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Cytosolic other (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:966377c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9663a000-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9663c81e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19801 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9663f1cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:966419ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9664421c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:96646a3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:966492b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9664babc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9664f978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9664f978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9664f978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9664f978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9664f978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9664f978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9664f978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:96656c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:96656c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9665a026-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21673 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Spermidine/spermine N(1)-acetyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9665c89e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75365 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein-tyrosine phosphatase 4A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:9665f0b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:966618a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04631 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Unclassified (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.36']} DrugCentral uuid:966640bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:96666902-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:96669102-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12974 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9666b916-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q93096 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9666e134-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:96670b3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.553']} DrugCentral uuid:96673e36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:96673e36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:96673e36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9667b9b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9668913c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9668913c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9668913c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9668d052-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:9668fb2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:9668fb2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:96692ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:2098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentostatin is inhibitor of Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.8']} DrugCentral uuid:966952fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56658 biolink:molecularly_interacts_with DrugCentral:2098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentostatin targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:96697ba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9669a3e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:9669c7be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9669efdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) DrugCentral uuid:966a13ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:966a3c12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:966a643a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:966a8c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:966ab67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:966ae19e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:966b0a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:966b337e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:966b5c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:966b8450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:966bac5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:966bd482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:966bfd18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:966c2540-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:966c4d86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:966c75a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:966ca204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:966ccc48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:966cf47a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.838']} DrugCentral uuid:966d1e78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:966d4696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:966d6eb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:966d96d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:966dbf40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:966de77c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:966e0f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:966e37b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:966e6896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:966e6896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:966e6896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:966eaaae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:966eaaae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:966eed70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:966eed70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:966eed70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:966eed70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:966eed70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:966f472a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:966f472a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:966f7a9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:966fa35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:966fcbaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:966ff3d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:96701bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.486']} DrugCentral uuid:9670467a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:96706eac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:967096c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9670bf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:9670e760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.027']} DrugCentral uuid:96710f74-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:96713332-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:96715bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) DrugCentral uuid:96717fa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:9671a362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23786 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:9671cb6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.828']} DrugCentral uuid:9671f362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:96721edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:96724e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:96724e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:96724e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:96728dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9672b702-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32198 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9672df0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:96730748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9673301a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9673582e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9673804c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2108 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perindopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9673a860-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:9673d182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.704']} DrugCentral uuid:9673fbbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:967423d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:96744bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9674743e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:96749c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9674c48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9674ecd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:967515a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:96753dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:96756600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:96758e32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9675b7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:9675dfb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:967607d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:967630e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:96765970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:967681a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:9676a9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9676d21a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:9676faec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.521']} DrugCentral uuid:96772314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.088']} DrugCentral uuid:96774b28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:96777346-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.481']} DrugCentral uuid:96779efc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9677c742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:9677f082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:96781918-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:96784140-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9678695e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacemide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:96788d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacetin targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:9678b18e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9678d9ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:967901e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:96792a10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:96795350-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96799f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:967a1b78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:967a4436-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:967a6c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:967a9558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:967abd9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:967ae5bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:967b0dee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:967b37a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:967b7694-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967b7694-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967b7694-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967b7694-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967b7694-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967b7694-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967b7694-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967bf84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:967bf84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:967bf84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:967bf84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:967bf84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:967bf84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:967bf84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:967c69d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:967c69d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:967ca0c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:967ca0c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:967ce344-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:967ce344-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:967ce344-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:967ce344-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:967ce344-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:967d38f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:967d5cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:967d84f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:967da914-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:967dd128-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.076']} DrugCentral uuid:967df93c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:967e2146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:967e49fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:967e720e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:967e9a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:967ec27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:967eee14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16853 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:967f193e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:967f4288-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:967f6aec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:967f92ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:967fbc0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:967fe3f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:2126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:968008da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9680310c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:968054c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione targets Enzyme (Prothrombin) DrugCentral uuid:9680786a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9680a182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2131 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:9680c7ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2131 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:9680eb92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:96810f5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:96813fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:96813fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:96813fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:96817dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.298']} DrugCentral uuid:9681a618-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.883']} DrugCentral uuid:9681ce18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:9681f230-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:968215d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:96824136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96824136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96824136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:968280f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:968280f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:968280f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9682bf44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9682e76c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:96831052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:96833992-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q834R3 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:968361ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:968389ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:9683b278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:9683dabe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:96841218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:96841218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:96841218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:96841218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:96841218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:96846fa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:96846fa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:96846fa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9684b5ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9684b5ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9684b5ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9684f5c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:96851de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9685461a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:96856e56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.745']} DrugCentral uuid:96859e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:96859e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:96859e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:9685d6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentermine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:9685faa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.801']} DrugCentral uuid:96862530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:96864fc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:968677e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:9686a00a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.667']} DrugCentral uuid:9686c936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:9686f168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.616']} DrugCentral uuid:96871990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.684']} DrugCentral uuid:968741e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:96876a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:968792a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:9687bae4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:9687e30c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:96880e36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:96883898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:968860c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:968888fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:9688b1c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9688d9e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:9689020a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:96892a82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:968952a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:96897ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:9689a2fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9689d4a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:9689d4a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:9689d4a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:968a1f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:968a1f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:968a1f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:968a5f2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:968a87f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:968ab00a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:968ad828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:968b00b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:968b28dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:968b517c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P98170 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Unclassified (E3 ubiquitin-protein ligase XIAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:968b79ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:968ba2d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:968bccb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:968bf078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:968c18aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:968c4514-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:968c4514-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:968c7822-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:968ca054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:968cc886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:968cf0fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:968d1944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:968d4158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:968d6994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:968d9b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:968d9b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:968d9b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:968de130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:968de130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:968de130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:968e27ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:968e27ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:968e27ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:968e6650-dc5e-11ec-be2c-0242ac110005 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:968e8e50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:968eb6b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:968eda86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:968f0290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:968f2ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:968f511e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:968f7946-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:968fa150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:968fc978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.166']} DrugCentral uuid:968ff218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:96901a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:9690427c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:96906aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:96909358-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9690bb80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:9690e484-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:96910cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:969136fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:96915ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:96917e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:9691a2f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:9691c714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9691ef46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:96921340-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:96923b7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:96926002-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:969283de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9692b3ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9692b3ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9692b3ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9692f332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phloroglucinol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:96931f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:96931f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:96935a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:96935a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:96935a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:969398fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:9693c118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.37']} DrugCentral uuid:9693e936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9694114a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:969439f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:969462ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:96948ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:9694b4d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:9694dff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:96950a96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:969532b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:96955ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:96958336-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:9695ab68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36196 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9695d386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9695fc58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:96962480-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:96964c94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9696b008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:96977fd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9697a7f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9697d0d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9697f986-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:969821a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:96984576-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:96986948-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:969894f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9698bf1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9698e742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9699202c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9699202c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9699202c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9699202c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9699202c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:969974aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:96999cf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:9699c5c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9699edea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:969a15fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:969a3e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilsicainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:969a69a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilsicainide is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.377']} DrugCentral uuid:969a91b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interleukin-5) DrugCentral uuid:969ab568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interferon gamma) DrugCentral uuid:969ad958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:969b01bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interleukin-2) DrugCentral uuid:969b2570-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) DrugCentral uuid:969b4956-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62658 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:969b7174-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:969b9a5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:969bc282-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:969bea96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:969c1796-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:969c1796-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:969c4b58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:969c738a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.862']} DrugCentral uuid:969c9b9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.798']} DrugCentral uuid:969cc416-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:969cec34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:969d143e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:969d3c48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.63']} DrugCentral uuid:969d652e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.559']} DrugCentral uuid:969d8d4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:969db574-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:969ddd92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.301']} DrugCentral uuid:969e070e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:969e2fb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:969e59ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:969e8206-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:969eaaa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:969ed2c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.709']} DrugCentral uuid:969efae2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:969f23be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.424']} DrugCentral uuid:969f4bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:969f7418-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:969f9c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:969fc594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:969ff078-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:96a0202a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:96a0202a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:96a0202a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:96a05eb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:96a086e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:96a0af04-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:96a0d718-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:96a0ff7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:96a127c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:96a14fd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:96a17808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:96a1a1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:96a1dbae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:96a1dbae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:96a1dbae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:96a1dbae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:96a1dbae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:96a231e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94782 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Enzyme (Ubiquitin carboxyl-terminal hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96a25a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EQ60 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:96a28220-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:96a2aa16-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:96a2d298-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60706 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil targets Ion channel (ATP-binding cassette sub-family C member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:96a2fa8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:96a32252-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:96a32252-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:96a355a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is partial agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:96a3801c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is partial agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:96a3a98e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:96a3d1c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:96a3f9de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96a422ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:96a44aec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.78']} DrugCentral uuid:96a472ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:96a49b14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.209']} DrugCentral uuid:96a4c3aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:96a4ebd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:96a51fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:96a51fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:96a51fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:96a51fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:96a575ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:96a575ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:96a575ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:96a5b440-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.943']} DrugCentral uuid:96a5dcea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:96a6051c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:96a62d44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.455']} DrugCentral uuid:96a65558-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:96a67dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:96a6a5e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.879']} DrugCentral uuid:96a6cde4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:96a6f602-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:96a71fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:96a747ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88275 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:96a77014-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:96a797f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96a7c0c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:96a7e8dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:96a810d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:96a838d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:96a86172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:96a88972-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.87']} DrugCentral uuid:96a8b190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:96a8dab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:96a903e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.461']} DrugCentral uuid:96a92d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:96a9556e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.992']} DrugCentral uuid:96a97da0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.256']} DrugCentral uuid:96a9a62c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:96a9ce54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:96a9f672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:96aa1f30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.105']} DrugCentral uuid:96aa4758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.799']} DrugCentral uuid:96aa6f8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.939']} DrugCentral uuid:96aa983e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:96aac1b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.189']} DrugCentral uuid:96aaea5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:96ab1250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:96ab3a5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:96ab62dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:96ab8b04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.429']} DrugCentral uuid:96abb304-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:96abdb18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:96ac03c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:96ac2bcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:96ac53f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:96ac7c08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:96aca584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:96accec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:96acf700-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.324']} DrugCentral uuid:96ad1f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:96ad47dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:96ad6ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:96ad982c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:96adc068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:96ade944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:96ae118a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:96ae39c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:96ae61da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:96ae8e80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:96ae8e80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:96aec3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:96aec3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:96aec3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:96af0036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:96af0036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:96af318c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:96af318c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:96af5f22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:96af82e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:96afab8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:96afea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:96afea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:96afea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:96afea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:96afea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:96afea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:96afea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:96b04b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:O18276 biolink:molecularly_interacts_with DrugCentral:2188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperazine targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) DrugCentral uuid:96b071d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipotiazine palmitate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:96b09d1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipotiazine palmitate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:96b0c56a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2199 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirbuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:96b0e9b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:96b111f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:96b13a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:96b16240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:96b18b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:96b1b358-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:96b1db9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:96b20448-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:96b22e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:96b256b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:96b27ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:96b2a722-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:96b2cfae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:96b306fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:96b306fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:96b306fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:96b306fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:96b306fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:96b36cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:96b36cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:96b36cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:96b36cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:96b36cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:96b3c29c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:96b3ec2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:2201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:96b416f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:96b43f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:96b4674c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:96b48fd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:96b4b7f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:96b4e028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:96b50850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:96b53136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:96b5595e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:96b5817c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:96b5a9cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:96b5d3e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:96b5fc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28347 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:96b62438-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:96b64c6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15562 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:96b674e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99594 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:96b69d14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:96b6c532-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirmenol targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:96b6e90e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:96b711ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:96b73a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:96b76712-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:96b76712-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:96b79fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:96b79fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:96b7d30a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:96b7f6dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:96b81ad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.168']} DrugCentral uuid:96b843ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:96b86c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:96b89556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:96b8bd92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:96b8e678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:96b90ea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:96b936e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:96b95f2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:96b988f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:96b9b12a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polythiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['9.09']} DrugCentral uuid:96b9d948-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralidoxime is activator of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.59']} DrugCentral uuid:96ba01de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08725 biolink:molecularly_interacts_with DrugCentral:2232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:96ba2a10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:2232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) DrugCentral uuid:96ba4de2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:96ba7614-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:96ba9edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.121']} DrugCentral uuid:96bac722-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:96baef5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:96bb1772-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:96bb41f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:96bb6a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.668']} DrugCentral uuid:96bb927e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:96bbbaa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:96bbe328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:96bc0b64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.282']} DrugCentral uuid:96bc33b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:96bc5c04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:96bc84ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:96bcad12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:96bcd90e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:96bcd90e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:96bd11a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:96bd11a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:96bd492a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:96bd492a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:96bd7c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:96bda488-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:96bdccec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:96bdf514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:96be1e4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:96be47d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Nuclear other (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:96be6ff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:96be9802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:96bec020-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:96beeaaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:96bf13d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:96bf3bfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:96bf6bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96bf6bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96bf6bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96bfa396-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:96bfcba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08515 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel targets Enzyme (Glutathione S-transferase class-mu 26 kDa isozyme) DrugCentral uuid:96bfef7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95US7 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB1) DrugCentral uuid:96c0138a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q962H3 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB2) DrugCentral uuid:96c037c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednicarbate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:96c05ba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:96c083b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:96c0a782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:96c0d1b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:96c0f9da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:96c121ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:96c14a0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:96c1763a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:96c19e76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:96c1c694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:96c1ef16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:96c21716-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:96c23f20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:96c26748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:96c290b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:96c2b70c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.28']} DrugCentral uuid:96c2df52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:96c3078e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:96c3306a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:96c3591e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:96c381be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:96c3aafe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:96c3d38a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:96c3fbbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:96c423d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:96c44bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:96c475c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:96c49e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:96c4c628-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:96c4ee64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:96c51704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone targets Cytosolic other (Annexin A1) DrugCentral uuid:96c53acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.801']} DrugCentral uuid:96c562ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:96c58b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:96c5b3bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:96c5dbd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:96c60402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:96c62c34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:96c655c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenalterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:96c67f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenalterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:96c6aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:96c6aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:96c6aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:96c6f5ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:96c6f5ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:96c6f5ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:96c73444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:96c75c6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:96c78502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:96c7ad34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.194']} DrugCentral uuid:96c7d55c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:96c7fd84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.799']} DrugCentral uuid:96c83150-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:96c83150-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:96c83150-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:96c87462-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.668']} DrugCentral uuid:96c89c6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.075']} DrugCentral uuid:96c8c548-dc5e-11ec-be2c-0242ac110005 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:96c8ea32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:96c91246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:96c93a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.739']} DrugCentral uuid:96c96304-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:96c98b0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:96c9aed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:96c9d7ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:96ca01c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35869 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transcription factor (Aryl hydrocarbon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:96ca29f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:96ca521e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:96ca7b5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:96caab56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96caab56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96caab56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:96cae292-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:96cb0aba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:96cb3332-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:96cb5b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:96cb8396-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:96cbabbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 8) DrugCentral uuid:96cbd1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 11) DrugCentral uuid:96cbf59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:96cc1dc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:96cc45f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:96cc6ea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.02']} DrugCentral uuid:96cc96d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:96ccbedc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.686']} DrugCentral uuid:96cce6e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96cd0f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95477 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol is inhibitor of Transporter (ATP-binding cassette sub-family A member 1) DrugCentral uuid:96cd338a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:96cd5c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:96cd8556-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.86']} DrugCentral uuid:96cdb09e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.812']} DrugCentral uuid:96cdd8bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:96ce00f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:96ce251a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:96ce48ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:96ce6caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96ceb82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:96cf3342-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.569']} DrugCentral uuid:96cf5cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.529']} DrugCentral uuid:96cf86c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:96cfaa70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.222']} DrugCentral uuid:96cfda18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:96cfda18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:96cfda18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:96d01d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:96d0452a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:96d06d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:96d095b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:96d0bdfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.764']} DrugCentral uuid:96d0e70a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:96d10f28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:96d13836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:96d16054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.207']} DrugCentral uuid:96d18868-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.402']} DrugCentral uuid:96d1b086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:96d1d976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:96d201b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:96d229b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:96d251da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:96d27a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.622']} DrugCentral uuid:96d2a266-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.324']} DrugCentral uuid:96d2ca84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.611']} DrugCentral uuid:96d2f2a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.723']} DrugCentral uuid:96d31c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.613']} DrugCentral uuid:96d345c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:96d36dcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.493']} DrugCentral uuid:96d395ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:96d3be62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:96d3e70c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:96d40f34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:96d4373e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:96d45fac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:96d48838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:96d4b04c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:96d4db3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.245']} DrugCentral uuid:96d50394-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:96d52bbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:96d553ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:96d57c70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.381']} DrugCentral uuid:96d5a498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:96d5cc8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:96d5f4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d61d10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.337']} DrugCentral uuid:96d64524-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:96d66d4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.907']} DrugCentral uuid:96d69574-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:96d6bf9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:96d6e808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:96d72700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d72700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d72700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d72700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d72700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d72700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d72700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:96d79a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:96d79a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:96d79a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d811e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d91dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96d9edfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.174']} DrugCentral uuid:96da162c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:96da3e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:96da6776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:96da8f94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:96dab79e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:96dadb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:96db04ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['9.876']} DrugCentral uuid:96db2dd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:96db55f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.94']} DrugCentral uuid:96db7e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35610 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Sterol O-acyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:96dba6a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:96dbceae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:96dbf6c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:96dc1eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:96dc4834-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:96dc703e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:96dc9866-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:96dcc0a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:96dcea3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:96dd164c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:96dd164c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:96dd4d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:96dd4d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:96dd8172-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:96dda986-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:96ddd1a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:96ddf9b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:96de2334-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:96de4b70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:96de738e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proglumide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.6']} DrugCentral uuid:96de9c38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proglumide is antagonist of GPCR (Gastrin/cholecystokinin type B receptor) DrugCentral uuid:96dec046-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0IJY2 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:96dee418-dc5e-11ec-be2c-0242ac110005 UniProtKB:O02604 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:96df07f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:96df2bd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:96df542a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:96df7c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:96dfa484-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:96dfccb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:96dff812-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:96e0221a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:96e04a38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.529']} DrugCentral uuid:96e073aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:96e09ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.656']} DrugCentral uuid:96e0c620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:96e0ee48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:96e116ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.226']} DrugCentral uuid:96e13f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:96e1679c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:96e18fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:96e1b8be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.551']} DrugCentral uuid:96e1e0d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:96e208e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:96e23118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.056']} DrugCentral uuid:96e259e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:96e28208-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:96e2aa12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.796']} DrugCentral uuid:96e2d21c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:96e2faa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:96e322c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:96e34ae4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:96e372e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:96e39c38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:96e3c4d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.344']} DrugCentral uuid:96e3ed0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.806']} DrugCentral uuid:96e4151e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:96e43e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:96e4665e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:96e48f58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:96e4bbb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:96e4bbb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:96e4fe16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:96e4fe16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:96e4fe16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:96e4fe16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:96e4fe16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:96e55b9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:96e55b9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:96e55b9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:96e59a06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:96e5c206-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promegestone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:96e5ea42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promegestone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:96e6142c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:96e63c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:96e66486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:96e68db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:96e6b5da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:96e6ddf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:96e70616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:96e72f88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:96e75aa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:96e784f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.188']} DrugCentral uuid:96e7ad32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.948']} DrugCentral uuid:96e7d6f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:96e7fad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:96e822ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:96e84b2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:96e873a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.941']} DrugCentral uuid:96e89bc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.823']} DrugCentral uuid:96e8c49c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.479']} DrugCentral uuid:96e8ecba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:96e916ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.382']} DrugCentral uuid:96e93f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.975']} DrugCentral uuid:96e96730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:96e98f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:96e9b7e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.452']} DrugCentral uuid:96e9dff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:96ea0834-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:96ea303e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:96ea58d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:96ea80c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:96eaa8c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:96ead192-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:96eafbb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:96eb23d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:96eb5392-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:96eb5392-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:96eb5392-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:96eb93b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:96ebbd00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:96ebe500-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:96ec0d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:96ec3654-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pronetalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:96ec5e90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:96ec86d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:96ecb070-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:96ecd88e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:96ecfc42-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:96ed1fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:96ed4468-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:96ed6844-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:96ed9076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:96edb89e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:96ede120-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:96ee0934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.029']} DrugCentral uuid:96ee3166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.728']} DrugCentral uuid:96ee5984-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:96ee8314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:96eeabc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:96eed3fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:96eefc04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.498']} DrugCentral uuid:96ef24e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:96ef4cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.337']} DrugCentral uuid:96ef7530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:96ef9e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.483']} DrugCentral uuid:96efc71a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:96efef2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:96f01760-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:96f03f88-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:96f069c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:96f091d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:96f0ba08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:96f0e212-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:96f10ab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.602']} DrugCentral uuid:96f136b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:96f136b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:96f169f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:96f193a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:96f1bbe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:96f1e414-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:96f20d40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:96f23662-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:96f25e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:96f28a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:96f28a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:96f28a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:96f2c99c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propentofylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:96f2f1b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:96f315fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(2) dopamine receptor) DrugCentral uuid:96f33b34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:96f35f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:96f383b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:96f3a786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:96f3cb44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:96f3ef0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:96f413f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:96f437be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:96f45b7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(4) dopamine receptor) DrugCentral uuid:96f47f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:96f4a3c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiram is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:96f4c77e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:96f4efa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.417']} DrugCentral uuid:96f517e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.031']} DrugCentral uuid:96f54064-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:96f56882-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.218']} DrugCentral uuid:96f59082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.005']} DrugCentral uuid:96f5b85a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:96f5e12c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:96f60918-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.119']} DrugCentral uuid:96f63140-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:96f65954-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:96f689c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96f689c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96f689c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96f6d0d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:96f6d0d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:96f6d0d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f74990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:96f823ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:96f823ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:96f823ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:96f862da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:96f88ada-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:96f8b37a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:96f8dbfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.913']} DrugCentral uuid:96f9050a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:96f92d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:96f95578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:96f97eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:96f9a83e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.699']} DrugCentral uuid:96f9d066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:96f9f884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:96fa212e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:96fa4960-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:96fa7156-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.319']} DrugCentral uuid:96fa9974-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:96fac1ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:96faeb4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.297']} DrugCentral uuid:96fb135e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:96fb3b7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:96fb6610-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:96fb8e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:96fbb6a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.01']} DrugCentral uuid:96fbdec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:96fc07e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:96fc3018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:96fc5822-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:96fc882e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:96fc882e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:96fc882e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:96fcc7a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:96fcefc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:96fd17f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:96fd421e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:96fd6a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:96fd92be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:96fdbae6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:96fde412-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49895 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil is inhibitor of Enzyme (Type I iodothyronine deiodinase) DrugCentral uuid:96fe07da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:96fe3002-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:2309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propyphenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.481']} DrugCentral uuid:96fe587a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:96fe7c42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:96fea474-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:96fea474-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:96fed796-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proscillaridin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:96ff011c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proscillaridin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:96ff26b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:96ff4ed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:96ff7700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:96ff9fbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R297 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Protein Trhr2; Thyrotropin releasing hormone receptor 2; Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:96ffc84a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:96fff05e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERT1 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:97001872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protokylol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:97003c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.928']} DrugCentral uuid:970065ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:97008e92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:9700b7a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9700e234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:97010c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:970134be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:97015cd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:97018586-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9701adcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9701d5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:9701fe08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:97022680-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:97024f20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:97027720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:97029ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:9702c09a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:9702e458-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:97030802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9703300c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:970358d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPB6 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cyclopropane mycolic acid synthase 1) DrugCentral uuid:97037c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50575 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Amidase; Nicotinamidase; Nicotinamidase/pyrazinamidase; Pyrazinamidase; Pyrazinamidase/nicotinamidase; Pyrazinamidase/nicotinamidase PncA) DrugCentral uuid:9703a03c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9703c878-dc5e-11ec-be2c-0242ac110005 UniProtKB:P95029 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide is inhibitor of Enzyme (3-oxoacyl-ACP synthase; Fatty acid synthase Fas; Probable fatty acid synthase Fas (Fatty acid synthetase)) DrugCentral uuid:9703ecc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:970414fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:97043d3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:97046558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:97048f92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:9704b8be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:9704e168-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:970509ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:97053276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:97055a9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.751']} DrugCentral uuid:970582c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:9705ab48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9705d384-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:9705fbac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:970624c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:97064e4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:97067672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:97069e72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:9706c67c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9706ef26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.288']} DrugCentral uuid:97071744-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.409']} DrugCentral uuid:97073f58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:9707680c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:9707908e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:9707b8ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9707e0c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:970808e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:97083354-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:97085bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:970883c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.009']} DrugCentral uuid:9708acd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9708d598-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:9708fdb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08966 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:970925de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K0H1 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Unclassified (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:97094df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9709766a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06865 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:97099e6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07686 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9709c69c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3V050 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Unclassified (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9709eed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:970a1994-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8I1R6 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:970a41c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1KRD8 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Unclassified (Fumarate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:970a6a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:970a9342-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43426 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Synaptojanin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:970abb60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:970aeb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:970aeb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:970aeb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:970b316c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:970b316c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:970b316c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:970b77d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:970b77d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:970b77d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:970bb75e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:970be328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:970c0dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:970c3666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.483']} DrugCentral uuid:970c5efc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:970c8850-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:970cb06e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:970cd896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:970d0118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:970d294a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:970d5172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:970d7990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:970da2f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:970dcd32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.512']} DrugCentral uuid:970df55a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.027']} DrugCentral uuid:970e1d6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.127']} DrugCentral uuid:970e4636-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:970e6e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:970e9686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:970ebe9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:970ee71c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:970f0f9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.795']} DrugCentral uuid:970f37c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.266']} DrugCentral uuid:970f5fda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:970f89a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:970fb1a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:970fdab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:971002f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.241']} DrugCentral uuid:97102bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:971053ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:97107c12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:9710a444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.506']} DrugCentral uuid:9710ccda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9710f516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:97111d3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.866']} DrugCentral uuid:97114638-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:97116ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9711996c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9711c194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9711ea48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:971212fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:97123b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:97126324-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:97128bba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9712b3d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:9712dc14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.542']} DrugCentral uuid:97130446-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:97132d68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.079']} DrugCentral uuid:9713559a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:97137dcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.459']} DrugCentral uuid:9713a5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:9713cfac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:9713f7d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.575']} DrugCentral uuid:97142010-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.558']} DrugCentral uuid:9714484c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:971470ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:971498d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:9714c114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:9714e964-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.574']} DrugCentral uuid:9715131c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:97153b3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:97156380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:97158c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9715b484-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:9715e06c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:9715e06c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:97161b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:97161b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:97161b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:97166528-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97166528-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97166528-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97166528-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9716aefc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00592 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9716d936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04055 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:971732b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9717f474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9717f474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9717f474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9718374a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9718374a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9718720a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9718720a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9718720a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9718b27e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:9718da92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.397']} DrugCentral uuid:971902ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:971926be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinethazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:97194ae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quingestanol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:97196fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:971997d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:9719bbb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:9719e00e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:971a03d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:971a27b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:971a4fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:971a7988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:971aa41c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:971acc30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:971af5c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:971b1e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.106']} DrugCentral uuid:971b466a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:971b6e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:971b9688-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:971bbf46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:971bef16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:971bef16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:971bef16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:971c2d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:971c56ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:971c7f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:971ca762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:971ccf9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is inhibitor of Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:971cf898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:971d21b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.102']} DrugCentral uuid:971d49d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:971d7214-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:971d96a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:971dbed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:971deafa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:971deafa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:971e1a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:971e431a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:971e6b9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:971e93c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:971ebc50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:971ee48c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:971f0cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:971f34e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:971f5dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.408']} DrugCentral uuid:971f85fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:971fae30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.205']} DrugCentral uuid:971fd676-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:971fffd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9720281a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:9720502e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:97207982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:9720a20e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:9720ca54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9720f2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:97211c0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:972144d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:97216d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:972194f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:9721bd4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:9721e628-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:97220e5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:9722365a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:97225f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.193']} DrugCentral uuid:9722874a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9722af72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:9722d79a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:9723004e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:97232876-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:97235076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:97237876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9723a2ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:9723cc04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:9723f42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.876']} DrugCentral uuid:97241c40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13393 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Phospholipase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:972444c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14939 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Phospholipase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:97246cb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:972494e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:9724bd12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.625']} DrugCentral uuid:9724e5d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:972510fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:97253b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:972563fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:97258f12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:9725bae6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:9725bae6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:9725ee44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:972616c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.66']} DrugCentral uuid:97263f52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:972668b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:972690f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9726b996-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9726e1b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:972709d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9727345c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:97275cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:972784f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9727acfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9727d506-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.244']} DrugCentral uuid:9727fd88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:972825ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:97284dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:97287948-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:9728a17a-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9728c998-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9728f29c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:97291c18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:97294594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is inverse agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:97296dbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:972995f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XKD3 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9729bf06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9729e74c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:2355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.9']} DrugCentral uuid:972a0f92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:2355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.39']} DrugCentral uuid:972a37e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:972a60c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramipril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:972a88f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:972ab118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:972ad940-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:972b030c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:972b2b34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:972b5366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:972b7bac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:972ba42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:972bcc38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:972bf032-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5YLN7 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Unclassified (Voltage-gated sodium channel Nav1.5 cardiac isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:972c1850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rebamipide is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:972c426c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:972c6a9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:972c92b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:972cbb5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:972ce7d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:972d107a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:972d388e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:972d611a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:972d894c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:972db552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:972db552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:972dec5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:972dec5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:972e2046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:972e485a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.398']} DrugCentral uuid:972e7078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:972e99d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:972ec442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:972eec88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:972f105a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:972f38c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:972f60f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:972f89ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:972fb1b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:972fda8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:9730029e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:97302ad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:973052f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:97307c56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9730a474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9730dcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9730dcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9730dcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9730dcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9730dcb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:973131be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09428 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Ion channel (ATP-binding cassette sub-family C member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:973159dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:97317d9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:9731ab44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:9731ab44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:9731e294-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:9731e294-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:973215f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reproterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:97323a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rescinnamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:97325e4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:97328672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.415']} DrugCentral uuid:9732aea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.232']} DrugCentral uuid:9732d71c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9732ff26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:97332762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:97334f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:9733783e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9733a052-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9733c88e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9733f0ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:97342270-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97342270-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97342270-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:973466f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:97349034-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.836']} DrugCentral uuid:9734b8ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol acetate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9734e0e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol acetate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9735092e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:97353156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Kinase (Adenosine kinase) DrugCentral uuid:973555b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22413 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 1) DrugCentral uuid:97357972-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49902 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (Cytosolic purine 5'-nucleotidase) DrugCentral uuid:97359d4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9735c60c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9735eede-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:973616fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (NS5B protein) DrugCentral uuid:97363ad8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:973662ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WGY9 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin targets Enzyme (DNA-directed RNA polymerase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:973696ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:973696ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:973696ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:973696ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:9736d916-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9737010c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:973729a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:973751c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:973779d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9737a206-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9737cc36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:9737f2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:97381b00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:9738433c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97386baa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:973893be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9738c73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:9738c73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:9738c73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:9738c73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:973908f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:97393c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:97393c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:97393c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:97393c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:97397d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9739a7fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9739d0ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:9739f920-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:973a215c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:973a49de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:973a722e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:973a95f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:973abe0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:973ae6f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:973b0f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:973b32cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:973b5ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:973b868c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:973baf40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:973bd740-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:973c00c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21430 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Ion channel (Matrix protein 2) DrugCentral uuid:973c24b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:973c4cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:973c74fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine is inhibitor of Ion channel (Matrix protein 2) DrugCentral uuid:973c98e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:973cc16e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:973ce978-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:973d11aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:973d3ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimexolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973d976a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:973e6708-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:973e8fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:973eb7da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q197X6 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:973edff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WS26 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:973f0816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:973f31d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:973f59ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:973f820a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:973faaf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:973fd30e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:973ffb22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9740234a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:97404cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:97407502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:97409d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9740c57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9740ef64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.788']} DrugCentral uuid:97411818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:974140ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.443']} DrugCentral uuid:974168d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.364']} DrugCentral uuid:97419194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9741b9a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9741e2ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:97420af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:97423388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:97425bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:974283ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:9742ac0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.023']} DrugCentral uuid:9742d752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:97430074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:9743289c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:97435150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:9743798c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9743a1a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:9743c9d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9743f27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:97441aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:974442c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.278']} DrugCentral uuid:97446aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:97449466-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9744bce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9744e4f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:97450d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.687']} DrugCentral uuid:974535d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:97455e32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9745865a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.967']} DrugCentral uuid:9745ae82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9745d7d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:97460012-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:97462844-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:97465198-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:97467bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:9746a404-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9746cc2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9746f44a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:97471d94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:9747459e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:97476dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:97479620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9747be48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:9747e67a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:97480eac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:974838be-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:974862da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9748966a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9748966a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9748966a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9748966a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9748e8f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:9748e8f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:9748e8f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:97492ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:97492ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:97492ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:97496ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:97499718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritodrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9749bf40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritodrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9749e74a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:974a10bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:974a3b14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:974a6346-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:974a8b46-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:974aafae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:974ad7e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:974afff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.303']} DrugCentral uuid:974b281c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:974b50d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.119']} DrugCentral uuid:974b7a1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:974ba256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:974bca7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:974bf454-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:974c1c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:974c44ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:974c6ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:974c959e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:974cbda8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.47']} DrugCentral uuid:974ce5da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:974d0e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:974d37b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:974d5fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:974d87ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:974db01e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:974ddb20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:974e0334-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:974e2b34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:974e5406-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:974e7cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:974ea4d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:974eccf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:974ef578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:974f1dbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:974f45dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:974f6e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:974f979e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:974fbfda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:974fe802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:975013d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:975013d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:97504f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:97504f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:97504f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:975098ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:975098ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:975098ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:975098ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9750e522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:97510d40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:97513568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.466']} DrugCentral uuid:97515e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:97518702-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9751aef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:9751d702-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9751ffac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:975227ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:97524fde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:975277fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9752a042-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9752c860-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9752f04c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9753184c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:97534290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:97536de2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:9753965a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9753be82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9753e722-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:97540f40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9754375e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:97545f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9754890c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:9754b13e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:9754d9ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:975501fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:97552ad8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9755530a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:97557b14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9755a3fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:9755cc0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:9755eff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:975613a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:97563798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:97565bba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:97567fa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:9756a4b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:9756c88e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9756f23c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:97571a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:97574278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:97576a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:97579318-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9757bb22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:9757e340-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:97580b5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:975833cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:97585bea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:975884f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:9758ada2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9758d7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9758fffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9759280e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:975950c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:975978c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9759a0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:9759c908-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:9759f1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:975a19bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:975a428e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:975a6aac-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:975a93a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:975abba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:975ae3d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:975b0bce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:975b3446-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:975b5c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:975b8478-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43924 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin targets Enzyme (Phosphodiesterase 6D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:975bac96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:975bd518-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:975bfd40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:975c2568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:975c4e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:975c7888-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:975ca0c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:975cc900-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxatidine acetate is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:975cf114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:975d15a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:975d3dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.261']} DrugCentral uuid:975d65fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rupatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:975d8e3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rupatadine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:975db69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:975ddec6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:975e06da-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3SIU2 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Unclassified (Met repressor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:975e2ffc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11086 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Phenylethanolamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:975e5a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22061 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Protein-beta-aspartate methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:975e824a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:975eaa54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:975ed312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.95']} DrugCentral uuid:975efb12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6RYA0 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Salicylic acid-binding protein 2) DrugCentral uuid:975f1eda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:975f46ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:975f6f7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:975f9798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:975fbfc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:975fe7d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:97601164-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:97603978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9760629a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.36']} DrugCentral uuid:97608ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9760b330-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9760db62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:976103b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:97612be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9761545c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:97617c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.004']} DrugCentral uuid:9761a498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9761cc98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9761f7cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:97621ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:97624934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:976271ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:976299ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:9762c1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:9762e9e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.282']} DrugCentral uuid:976312ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.699']} DrugCentral uuid:97633b14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.555']} DrugCentral uuid:97636332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.556']} DrugCentral uuid:97638b3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:9763b080-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.003']} DrugCentral uuid:9763d9d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.153']} DrugCentral uuid:976401f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.187']} DrugCentral uuid:97642a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.661']} DrugCentral uuid:9764529c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:97647ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:9764a3d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9764cbd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9764f4ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:97651ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:976544ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:97656d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:976596f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9765bf24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9765e76a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:976617b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:976617b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:976617b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:97665678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:97667e82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:9766a6b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9766cf2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:9766f74a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:97671f5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:97674786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:976772b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:97679d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:9767c5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9767fd7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9767fd7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9767fd7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9767fd7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9767fd7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:976854b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:2427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secnidazole targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:97687cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.578']} DrugCentral uuid:9768acfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:9768acfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:9768acfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:9768e42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.171']} DrugCentral uuid:97690c4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.764']} DrugCentral uuid:97693672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:97696084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:976988a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:9769b0ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9769d938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:976a016a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:976a2d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:976a2d66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:976a60e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 seratrodast targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:976a8900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:2433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sermorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:976aacdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:976ad0a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertaconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:976af8e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:976b2450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:976b4c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:976b74a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.194']} DrugCentral uuid:976b9e3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:976bc66c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:976bef02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:976c1734-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:976c4362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:976c6b9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:976c93d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:976cbc02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:976ce51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:976d0d38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:976d3682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:976d5ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:976d8754-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:976daf7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:976dd7ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:976dffea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:976e28a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:976e50c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:976e78da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:976ea0f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:976ecc5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:976ef4ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:976f1d12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:976f459e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:976f755a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:976f755a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:976f755a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:976fbc68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:976fbc68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:976fbc68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:976ffba6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:977023c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:97704c1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9770743c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.965']} DrugCentral uuid:97709fa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9770c8ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:9770f0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.54']} DrugCentral uuid:97711982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:97714204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:97716a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:97719254-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.246']} DrugCentral uuid:9771bacc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:9771e2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.082']} DrugCentral uuid:97720b80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:9772338a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:97725d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:97728556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:9772ad74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:9772d6b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:9772ff54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:97732862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9773506c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.475']} DrugCentral uuid:97737894-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:9773a10c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:9773c948-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:9773f166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:9774198e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:977443b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:97746bdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:97748fae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:9774b380-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:9774d806-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:9774fbec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:97751fc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:977543a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9775a0b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:97765e74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:977686e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:9776afbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:9776d8ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:9776fdf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.026']} DrugCentral uuid:9777262e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97774eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:977776e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.538']} DrugCentral uuid:97779f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9777c71e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9777f1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:977819e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:97784298-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Transporter (Multidrug resistance-associated protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97786b4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:97789360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) DrugCentral uuid:9778b728-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9778df28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:97790796-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97792f96-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:977957be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:97797fdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9779a912-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9779d202-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9779fb38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.094']} DrugCentral uuid:977a236a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:977a4c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:977a7446-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:977a9c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16586 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:977ac46e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:977aecf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:977b150e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:977b4100-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:977b4100-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:977b80fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:977b80fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:977b80fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:977b80fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:977bdc8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:977bdc8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:977bdc8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:977bdc8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:977c2e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:977c2e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:977c2e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:977c716a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:977c716a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:977cb814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:977cb814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:977cb814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:977cb814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:977cb814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:977cb814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:977d2060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:977d2060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:977d2060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:977d5fe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:977d8802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14099 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:977db016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:977dd83e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:977e00fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:977e292e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:977e516a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:977e79a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:977ea228-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.73']} DrugCentral uuid:977eca46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:977ef2fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:977f1b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:977f452a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:977f6d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:977f9548-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:977fbe06-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:977fe638-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:97800e56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9780366a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:97805fe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:97808818-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9780b05e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14142 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:9780d87c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:9780fda2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:978127e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:97815022-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:9781784a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9781a11c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q10283 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:9781c93a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.431']} DrugCentral uuid:9781f16c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:97821962-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:978241d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:978269ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:978291f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:9782b9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9782e374-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:97830b6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9783336a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:97835b92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q53EL6 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Nuclear other (Programmed cell death protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9783843c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06730 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Nuclear other (Eukaryotic translation initiation factor 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9783ac46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26883 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9783d43c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2447 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sisomicin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:9783f7fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:97842086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:97844a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.774']} DrugCentral uuid:97847252-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:97849a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9784c360-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9784eb88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:978513ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHL4 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:97853c64-dc5e-11ec-be2c-0242ac110005 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:97856482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:2449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitafloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:9785884a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:2449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitafloxacin targets Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:9785ac12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:9785d41c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9785fcb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:978624d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:97864cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:97867584-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:97869da2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9786c5b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (DNA polymerase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:9786edd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:978717c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:97873ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:97876836-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:9787904a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9787b8a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24158 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Myeloblastin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9787e086-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3UP87 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:97880872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9788309a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:97885af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:97888310-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9788ab42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9788d374-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9788fc46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9789245a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:97894c82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:97897522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:97899dae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:9789c5e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:9789ee12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:978a164e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:978a3ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:978a6824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:978a906a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:978ab87e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:978ae150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:978b0982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:978b3196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:978b5a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:978b8218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:978baa54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:978bd2d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:978bfc20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:978c247a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:978c4d92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:978c75ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:978c9ea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:978cc6f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:978cf04e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:978d1880-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:978d4102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:978d6934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:978d915c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:978db966-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:978de440-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:978e0c90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:978e349a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:978e5cc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:978e8580-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:978ead94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:978ed5bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:978efde4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:978f267a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:978f4f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:978f7724-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:978fa046-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:978fca76-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:978ff28a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:97901a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9790447e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:97906ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:979094c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9790bcec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9790e578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:97910d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:97913582-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:97915da0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:97918668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53778 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9791aea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9791d6b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9791fec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:97922776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:97924f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:979277c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:97929fe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9792c848-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9792f188-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:979319a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:979341c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:97936b7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9793939a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9793bbae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9793e462-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:97940c8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:97943598-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:97945dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9794864c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9794ae6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9794d66a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9794fe88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97952750-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:97954f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:979577a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:97959fc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9795c926-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15264 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9795f158-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97961958-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9796416c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:979669da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:97969202-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9796ba16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9796e234-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:97970cd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:979734f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:97975d04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:97978518-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:9797adfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9797d5f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9797fe12-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:97982766-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:97984f8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:979877c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:97989fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9798c900-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9798f2b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:97991ae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00526 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:97994326-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:97996bd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:979993f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9799bbf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9799e3f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:979a0c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:979a3498-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:979a5cc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVW4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:979a84ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:979aadf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:979ad614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:979afe1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:979b263c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:979b4f0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:979b7722-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:979b9f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:979bc768-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:979befe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:979c18f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:979c410c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:979c692a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:979c9440-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:979cbcfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5GIT4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:979ce51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:979d0dda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:979d35ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:979d5e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05622 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:979d8648-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:979daeb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:979dd6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:979dfefc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:979e2706-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:979e5032-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:979e7846-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:979ea050-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:979ec86e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XZT6 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Deoxynucleoside kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:979ef226-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00142 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:979f1a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:979f429e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:979f6ad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:979f9370-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:979fbb8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:979fe3ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.413']} DrugCentral uuid:97a010a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:97a010a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:97a04298-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:97a04298-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:97a0701a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spectinomycin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:97a093d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2469 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiclomazine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:97a0bc6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:97a0e4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:97a10cdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:97a134dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:97a15d54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:97a18572-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:97a1ad9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:97a1d5cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97a1ff70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:97a2278e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:97a24fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:97a277e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:97a2a088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.322']} DrugCentral uuid:97a2c89c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:97a2f0c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:97a318c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:97a34182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:97a369b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:97a391be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:97a3b9d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:97a3e34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:97a40c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:97a434ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:97a45d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:97a48560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:97a4aec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:97a4d704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:97a4fff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:97a52830-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:97a55058-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:97a57876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:97a5a148-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97a5c970-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:97a600ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:97a600ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:97a600ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:97a600ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:97a600ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:97a66132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:97a66132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:97a66132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:97a66132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:97a6b9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:97a6b9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:97a6b9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:97a6b9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:97a6b9f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:97a71762-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:97a71762-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:97a71762-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:97a75d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:97a75d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:97a75d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:97a7aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:97a7aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:97a7aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:97a7aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:97a7aef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:97a80352-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:97a82c1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:97a85456-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:97a87c9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spirapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:97a8a532-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spirapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:97a8ce7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.227']} DrugCentral uuid:97a8f71c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:97a91b02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.884']} DrugCentral uuid:97a94438-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:97a96e22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.029']} DrugCentral uuid:97a99636-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:97a9be4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:97a9e6ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:97aa0ecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.663']} DrugCentral uuid:97aa37f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:97aa6002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:97aa8870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.327']} DrugCentral uuid:97aab098-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:97aad8d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:97aafc92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.948']} DrugCentral uuid:97ab2668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:97ab4e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:97ab76b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.316']} DrugCentral uuid:97ab9eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:97abc320-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:97abeb3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:97ac1334-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:97ac36f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:97ac5f4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:97ac831e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:97aca6dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WH62 biolink:molecularly_interacts_with DrugCentral:2481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 streptomycin targets Ribosomal protein (30S ribosomal protein S12) DrugCentral uuid:97accaa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:97acf498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:97ad1d38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:97ad454c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:97ad6d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97ad9d76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:97ad9d76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:97ad9d76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:97addb74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07727 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:97ae0482-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:97ae2cdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is agonist of GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.367']} DrugCentral uuid:97ae54f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:2487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinic acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:97ae7e12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXA5 biolink:molecularly_interacts_with DrugCentral:2487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinic acid is agonist of GPCR (Succinate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97aea644-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:97aee1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:97aee1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:97aee1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:97aee1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:97aee1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:97af3366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:97af5c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:97af8424-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:97afac42-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:97afd442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:97affcce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97b03022-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:97b03022-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:97b03022-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:97b03022-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:97b079ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:97b0a2e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97b0cae6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:97b0f2f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:97b11b04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:97b1441c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:97b16d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:97b19570-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:97b1bd7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:97b1e5de-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:97b20de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:97b235f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:97b25e1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:97b286f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:97b2af1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7X575 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:97b2d71e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0VTR6 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:97b2ff28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0VTR8 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:97b327d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:D5HSX5 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:97b34fd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P83111 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Serine beta-lactamase-like protein LACTB, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:97b377d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:97b3a1a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0VTS0 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (ADC-18 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:97b3c9b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00809 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:97b3f1b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:97b419b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:97b44374-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:97b46b9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:97b493ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:97b4bbba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:97b4e4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:97b50ce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.716']} DrugCentral uuid:97b5350e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:97b55d36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.786']} DrugCentral uuid:97b5869e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:97b5aeee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:97b5d720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:97b5ff3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.258']} DrugCentral uuid:97b628b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:97b650e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.144']} DrugCentral uuid:97b67928-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:97b6a150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:97b6c9c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:97b6f1f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:97b715c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:97b73dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:97b7663a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:97b78e58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:97b7b676-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:97b7de80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.431']} DrugCentral uuid:97b80914-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.738']} DrugCentral uuid:97b8311e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:97b85928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:97b881be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:97b8aa18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:97b8d222-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97b8fa40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:97b9233a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:97b94b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97b96f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:97b999c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacytine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:97b9bf16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:97b9e734-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:97ba0f48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:97ba3310-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97ba5746-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:97ba7f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZV3 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:97baa75a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimethoxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:97bacf8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimidine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97baf3ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimidine targets Enzyme (Lactoylglutathione lyase) DrugCentral uuid:97bb1820-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2503 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadoxine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:97bb3bde-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IAU3 biolink:molecularly_interacts_with DrugCentral:2503 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadoxine targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:97bb6410-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:2504 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaethidole targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:97bb8c24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:97bbbcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:97bbbcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:97bbbcf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:97bbfb78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2510 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamerazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97bc1f68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfameter is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97bc4380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethizole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97bc6752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08192 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Bifunctional protein FolC) DrugCentral uuid:97bc8b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:97bcb34c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:97bcdbb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:97bd03e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:97bd2bf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfalene is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97bd4fa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:97bd7886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:97bda1a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:97bdc9d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:97bdf1f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:97be1a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97be3e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:97be667e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:97be8eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:97beb782-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:97bedfaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:97bf0976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:97bf3194-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:97bf5c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:97bf846e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:97bfaca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:97bfd52c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:97bffd40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:97c02554-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:97c04d7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:97c07662-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:97c09e80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:97c0c6b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:97c0eebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:97c1184c-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:97c142fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:97c16b1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:97c19344-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:97c1bc84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:97c1e4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:97c20ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:97c234fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:97c25dc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:97c285ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:97c2ae14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaphenazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:97c2d650-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaphenazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97c2fbee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfapyridine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97c31fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q49184 biolink:molecularly_interacts_with DrugCentral:2524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfapyridine targets Enzyme (Dihydropteroate synthase type-1) DrugCentral uuid:97c34392-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:97c36bf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:97c39464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24752 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Acetyl-CoA acetyltransferase, mitochondrial) DrugCentral uuid:97c3b840-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:97c3dc08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:97c4041c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:97c42d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.707']} DrugCentral uuid:97c4555c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.628']} DrugCentral uuid:97c47d70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:97c4a5a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:97c4d04a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.768']} DrugCentral uuid:97c4f872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.198']} DrugCentral uuid:97c52464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:97c52464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:97c5524a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:97c57a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:97c5a2b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:97c5cba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.161']} DrugCentral uuid:97c5f470-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:97c61c98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25084 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets Unclassified (Transcriptional activator protein LasR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:97c6448e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:97c6687e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:97c69222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:97c6bc2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:97c6e43e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:97c70c52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:97c7307e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:97c75446-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:97c77c78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:97c7a496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:97c7cd40-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfobromophthalein targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:97c7f52c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulforidazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:97c81d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulforidazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:97c84572-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:2533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesulfone is inhibitor of Enzyme (Dihydropteroate synthase 1) DrugCentral uuid:97c86a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesulfone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:97c88de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:97c8b5f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97c8ddfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:97c90638-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:97c92e42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:97c95638-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (72 kDa type IV collagenase) DrugCentral uuid:97c979ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:97c9a2b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.362']} DrugCentral uuid:97c9caa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:97c9f386-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:97ca1c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:97ca4610-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:97ca71d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:97ca9a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:97cac23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.307']} DrugCentral uuid:97caead4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:97cb12e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.857']} DrugCentral uuid:97cb3af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.508']} DrugCentral uuid:97cb631a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:97cb8bec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.146']} DrugCentral uuid:97cbb414-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:97cbdc3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.053']} DrugCentral uuid:97cc045a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:97cc3010-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:97cc58e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.196']} DrugCentral uuid:97cc810a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:97cca9a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.426']} DrugCentral uuid:97ccd1dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:97ccfa04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:97cd2240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:97cd4af4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:97cd72f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.141']} DrugCentral uuid:97cd9b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.645']} DrugCentral uuid:97cdc326-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:97cdee14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:97ce16c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:97ce3efa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:97ce6718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97ce8f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:97ceb7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97cedfc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:97cf07d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:97cf3094-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:97cf58bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:97cf80f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:97cfa92a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:97cfd2a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:97cffb5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:97d02378-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:97d04ccc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GJU1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:97d0754e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:97d09d80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:97d0c59e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:97d0ee70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:97d11684-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:97d13ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:97d166a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:97d1901e-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:97d1b896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:97d1e0b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:97d209cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:97d2419e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97d2419e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97d2419e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97d2419e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97d2419e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:97d29612-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:97d2be44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:97d2e70c-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:97d30f34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:97d33766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:97d36038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:97d38860-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:97d3b088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:97d3d8a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:97d4011e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.38']} DrugCentral uuid:97d4290a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:97d45128-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:97d47928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:97d4a1e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:97d4ca04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:97d4f204-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:97d51a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:97d543a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:97d56bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:97d593e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:97d5bd74-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:97d5e740-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:97d60f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:97d637b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:97d65fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:97d6889e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:97d6b0a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:97d6d8c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2541 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.571']} DrugCentral uuid:97d700d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2541 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:97d729c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:97d751e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:97d77a1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:97d7a288-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:97d7caba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:97d7f2e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:97d81b28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:97d843b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:97d86bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:97d893d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:97d8bbe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:97d8e558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:97d910a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:97d93990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:97d96190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:97d98a26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:97d9b320-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:97d9db3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:97da035c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:97da2bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N2B7 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:97da53e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8MI13 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Unclassified (5-hydroxytryptamine 1D receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:97da7bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:97daa41a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97dace68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:97daf668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:97db1e72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.12']} DrugCentral uuid:97db46a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:97db6f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:97db9820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:97dbc034-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97dbe9d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:97dc120a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:97dc3a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:97dc6250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:97dc8bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:97dcb61a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:97dcde38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:97dd0660-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:97dd2f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:97dd5728-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:97dd7f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:97dda854-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:97ddd0cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:97ddf8e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:97de2126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:97de493a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:97de7306-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:97de9b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:97dec342-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:97deeb7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:97df13e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:97df3c14-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:97df6428-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:97df8c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:97dfb4b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:97dfdcdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:97e00504-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:97e02dfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:97e05860-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:97e08092-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:97e0a8b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:97e0d13c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97e0f950-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:97e12178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:97e149a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:97e1720e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:97e19b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:97e1c4b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:97e1ed6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:97e216a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:97e23ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:97e266e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:97e28efa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:97e2b7e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:97e2dff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:97e30812-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:97e3301c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:97e3589e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:97e380a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:97e3a8bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97e3d0da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:97e3fb50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:97e4236e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:97e44b96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:97e4745e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:97e49c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:97e4c49a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:97e4ecc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:97e5153a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:97e53d3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:97e5654e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97e58e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:97e5b814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:97e5e1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:97e609ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:97e631fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:97e65abc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2H1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:97e682e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:97e6ab02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:97e6d320-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:97e6fbac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:97e723b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:97e74bc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:97e773e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:97e79cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:97e7c60e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:97e7ee2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:97e8164a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:97e83f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:97e86730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:97e88f4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:97e8b848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:97e8e05c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:97e90870-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:97e9307a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:97e959a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:97e984d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:97e9ad0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:97e9d534-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:97e9fdf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:97ea2606-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:97ea4e10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:97ea764c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:97ea9ece-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:97eac6d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97eaeef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:97eb1714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:97eb4086-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:97eb68b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:97eb90cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:97ebb908-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:97ebe1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:97ec09e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:97ec31ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:97ec5a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:97ec827a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:97ecaaa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:97ecd2c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:97ecfad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:97ed2630-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:97ed4e4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:97ed7766-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:97eda024-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:97edc978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97edf1aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:97ee19d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:97ee4254-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:97ee6a7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:97ee929a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:97eebaae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:97eee4ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:97ef0d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:97ef35ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:97ef5e0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:97ef86c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:97efaef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:97efd718-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:97efff36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:97f027b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:97f04fc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:97f077cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:97f09ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:97f0ca38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:97f0f256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:97f11a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:97f1426a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:97f16c36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:97f1945e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:97f1bc90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:97f1e51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:97f20d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:97f2354e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:97f25d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:97f286fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:97f2b244-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:97f2dc74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:97f3049c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:97f32d5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:97f35578-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:97f37d6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:97f3a58c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:97f3cf3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:97f3f758-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:97f41f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:97f44776-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:97f47098-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:97f498ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:97f4c0ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:97f4e8f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:97f514ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:97f53d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:97f56610-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:97f58e88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:97f5b6c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:97f5df82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:97f607b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:97f630fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:97f6591c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:97f68130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:97f6a94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:97f6d1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:97f6f9da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:97f72202-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11799 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:97f74a0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:97f77270-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:97f79a98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:97f7c2c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:97f7ead4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:97f815b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCP0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:97f83ebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:97f866d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:97f88eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:97f8b766-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:97f8df66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:97f9077a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:97f92f84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:97f958f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:97f9811e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:97f9a950-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:97f9d3bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:97f9fbf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:97fa2416-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:97fa4c34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:97fa74b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:97fa9cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:97fac4e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:97faed24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:97fb1588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:97fb3da6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:97fb65c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:97fb8de2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:97fbb740-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:97fbdf68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:97fc077c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:97fc2fae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:97fc5812-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80370 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Unclassified (Protein delta homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:97fc80da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:97fca8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:97fcd0f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:97fcf97a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:97fd217a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:97fd4a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:97fd7292-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:97fd9e02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:97fdc620-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:97fdee3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:97fe16d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:97fe3ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:97fe6706-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:97fe8f10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:97feb79c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:97fedfce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:97ff07f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:97ff3000-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:97ff59ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:97ff824e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:97ffaa62-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:97ffd3ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:97fffc38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:98002442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.23']} DrugCentral uuid:98004c74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9800747e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:98009ce2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9800c4ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9800ecf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:980115e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9801416a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:98016b86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:980193ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9801bbcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9801e444-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:98020c62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9802348a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:98025d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9802850c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9802ad34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9802d566-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9802ff1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:980328a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:980350d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:98037912-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9803a450-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9803cf20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9803f72a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:98041f48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:980447b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:98046fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:980497e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9804c006-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H8M2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Unclassified (Bromodomain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9804ea04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:98051308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.509']} DrugCentral uuid:98053b3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:98056376-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:98058c02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.959']} DrugCentral uuid:9805b43e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9805dd7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:98060646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:98062e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47872 biolink:molecularly_interacts_with DrugCentral:2548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secretin human is agonist of GPCR (Secretin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:980656aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:98067ebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9806a83a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:9806d274-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:9806fa92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:980722c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04844 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Acetylcholine receptor subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:98074b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9807730a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:98079b1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:9807c328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9807ebfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:98081418-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:98083c22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:98086418-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:98088d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9808b5a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:9808ddd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:980906d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:98092f4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9809576a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:98098000-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01984 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9809a80a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9809d0e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9809f904-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.61']} DrugCentral uuid:980a2514-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:980a2514-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:980a5d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:980a5d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:980a9f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:980a9f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:980a9f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:980a9f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:980a9f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:980af3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:980b1c12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:980b4552-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:980b6d5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:980b95e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:980bbdde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:980be5de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.398']} DrugCentral uuid:980c0df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interleukin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:980c3796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:980c60ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:980c88c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:980cb0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:980cd94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:980d016c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15393 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Nuclear other (Splicing factor 3B subunit 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:980d2976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96AY3 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:980d5176-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:980d7a52-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:980da284-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:980dcab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:980df2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:980e1d7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:980e457c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:980e8096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:980e8096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:980e8096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:980e8096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:980e8096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:980e8096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:980ef328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:980ef328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:980ef328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:980ef328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:980ef328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:980ef328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:980f5476-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:980fb574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98106dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:98109606-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9810be24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9810e214-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:98110ac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:98113318-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:98115b18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:9811834a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.915']} DrugCentral uuid:9811ad2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9811d66a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:9811fe88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:981227b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:98125040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:98127886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9812a0b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9812c8d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9812f158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:98132146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:98132146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:98132146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:98135fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 taltirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:98138938-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.807']} DrugCentral uuid:9813b156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.001']} DrugCentral uuid:9813d99c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:981401c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:98142a82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:981452d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:98147c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.335']} DrugCentral uuid:9814a494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9814cd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.139']} DrugCentral uuid:9814f566-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:98151d98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:981545a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:98157126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:98159bc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:9815c3ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:9815ed9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:981615ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:98163e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:98166658-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.618']} DrugCentral uuid:98168eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:9816b7b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.794']} DrugCentral uuid:9816dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:98170838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:981732b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:98175cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.557']} DrugCentral uuid:98178538-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:9817ad60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:9817d63c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.731']} DrugCentral uuid:9817fe5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:98182678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.238']} DrugCentral uuid:98184ebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.835']} DrugCentral uuid:9818774a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.858']} DrugCentral uuid:98189f86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:9818c7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:9818f044-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:98191a74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.611']} DrugCentral uuid:981942b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.204']} DrugCentral uuid:98196b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:981993c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9819bbe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.328']} DrugCentral uuid:9819e512-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:981a0d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:981a35da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:981a5e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:981a877e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:981aafba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.095']} DrugCentral uuid:981ad9c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.923']} DrugCentral uuid:981b01ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:981b2a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.038']} DrugCentral uuid:981b523a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:981b7abc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.913']} DrugCentral uuid:981ba2e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.821']} DrugCentral uuid:981bcb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.919']} DrugCentral uuid:981bf33e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:981c1c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.604']} DrugCentral uuid:981c4438-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.761']} DrugCentral uuid:981c6c74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.419']} DrugCentral uuid:981c953c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.515']} DrugCentral uuid:981cbfe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.587']} DrugCentral uuid:981ce80c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:981d102a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:981d38ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:981d60de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:981d88f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:981db4ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:981db4ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:981dea0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:981e1240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:981e3a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:981e62d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:981e8d60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:981eb5a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:981eddf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:981f061e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:981f2ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:981f56fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:981f7f36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:981fa812-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:981fd058-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:981ff876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:982020bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:982055be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:982055be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:982055be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:982055be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9820a0c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9820c8e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9820f172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:982119b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:982141f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:98216b20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:982193de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9821bbe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:9821e49c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:98220cf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:98223834-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9822605c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:9822887a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:9822b084-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q46991 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (IMI-1; IMI-1 carbapenemase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9822d906-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9823011a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6W9J1 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:98232938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:982351e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P94958 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:98237a14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05193 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9823a21e-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9823ca64-dc5e-11ec-be2c-0242ac110005 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9823f3b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:98241db6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:982445d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:98246e06-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9824966a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9824be9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9824e6b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:98250ec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:98253778-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:98255f8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:98258886-dc5e-11ec-be2c-0242ac110005 UniProtKB:B8R6A5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9825b0a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:9825da02-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:98260220-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:98262b56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:98265374-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:98267bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1A) DrugCentral uuid:98269fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9826c7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:9826ebb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9827149e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod is partial agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:98273cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:2580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teicoplanin aglycone is inhibitor of Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:98276502-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:98278d84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9827b7b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9827e05e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.31']} DrugCentral uuid:98280886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:982830a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:9828591c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:98288144-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:9828a976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9828d23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:9828fd9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:9828fd9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:9828fd9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:982934e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.444']} DrugCentral uuid:98295dee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:982983b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9829a7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:9829cb76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:9829ef2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:982a134c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:982a3714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:982a5f3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:2592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:982a875a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir disoproxil targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:982aab9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir disoproxil is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:982acf62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:982af33e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.943']} DrugCentral uuid:982b1b48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:982b4488-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.628']} DrugCentral uuid:982b6d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.388']} DrugCentral uuid:982b9690-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:982bbeb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:982be794-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:982c0b7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.662']} DrugCentral uuid:982c33b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52020 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:982c5be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2598 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbutaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:982c8474-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2598 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbutaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:982cac92-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.373']} DrugCentral uuid:982cd4b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:982cfcd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.895']} DrugCentral uuid:982d25dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.433']} DrugCentral uuid:982d4e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:982d77c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.216']} DrugCentral uuid:982da002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.599']} DrugCentral uuid:982dc8fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.632']} DrugCentral uuid:982df138-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.438']} DrugCentral uuid:982e196a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:982e4192-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:982e6a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.862']} DrugCentral uuid:982e9264-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:982ebaa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:982ee2c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:982f0cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:982f350c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:982f5d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:982f85f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:982fae4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:982fd21e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.666']} DrugCentral uuid:982ffa46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.963']} DrugCentral uuid:983022e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:98304b18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:98307340-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.612']} DrugCentral uuid:98309b5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.102']} DrugCentral uuid:9830c46c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.389']} DrugCentral uuid:9830ecbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:983114ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:98313d20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:983166a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.874']} DrugCentral uuid:98319022-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.687']} DrugCentral uuid:9831b872-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:9831e09a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:9832091c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:9832314e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:98325980-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:983281b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9832ab42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:9832d37e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:9832fbba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:98332496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:98334d40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:98337572-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:98339d90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.448']} DrugCentral uuid:9833c5c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9833ee62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:98341676-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51589 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Enzyme (Cytochrome P450 2J2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:98343e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9834673e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:98349132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.734']} DrugCentral uuid:9834b96e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:9834e18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:983511e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:983511e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:983511e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:98355162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:98357962-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9835a234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9835ca70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9835f2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:98361ade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:98364464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:98366eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:98369734-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9836bf66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9836e7f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:98371006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:9837395a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9837618c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:98378a72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9837b2a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9837dac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:983802fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:98382df6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9838563c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:98387e46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:9838a66e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9838cf04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9838f740-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terodiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:98392030-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.087']} DrugCentral uuid:98394876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9839715c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:98399998-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9839c1de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9839ebd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testolactone is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:983a1418-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:983a3c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:983a6486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:983a8cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:983ab51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:983add58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:983b0576-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:983b2e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:983b568e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.599']} DrugCentral uuid:983b7ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:983baae4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:983baae4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:983be1da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:983c0cdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone undecanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:983c30ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:983c5926-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:983c814e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:983ca976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:983cd19e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:983cfb56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:983d24aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:983d5484-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:983d5484-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:983d5484-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:983d941c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:983dbe2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:983de656-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:983e0e9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:983e375a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:983e5f78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel protein type 8 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:983e87be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:983eafdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.499']} DrugCentral uuid:983ed8a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00194 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:983f089c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:983f089c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:983f089c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:983f4f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:983f4f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:983f4f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:983f90c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:983fb490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:983fd84e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:2612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sapropterin targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.95']} DrugCentral uuid:984000c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00439 biolink:molecularly_interacts_with DrugCentral:2612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sapropterin is activator of Enzyme (Phenylalanine-4-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:98402a38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:9840527e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:98407ab0-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9840a3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:9840cbd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:9840f404-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.432']} DrugCentral uuid:98411c18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:984145bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:98416ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:98419706-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9841bf38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.393']} DrugCentral uuid:9841e7ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:98421014-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:9842385a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:984261b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:98428ad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9842b316-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9842db3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9843035c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:98432c42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:98435474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:98437c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9843a4b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9843cd3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9843f55a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:98442246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:98442246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:98445630-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:984489c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:984489c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:984489c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:984489c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9844da9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9844da9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9844da9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:98451cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:98454522-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:98456d72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS9 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Unclassified (Transmembrane domain-containing protein TMIGD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:9845966c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:9845be8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:9845e69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09508 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) DrugCentral uuid:98460a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:98463338-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:98465b60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AE18 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:98468374-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9846b344-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:9846b344-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:9846b344-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:984702e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:984702e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:984702e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:984702e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:984702e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:984702e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:984702e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:98476398-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:98478742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9847af4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98481112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9848c634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:9848ee70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:984916b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:98493f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:98496756-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:98498f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9849b7a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9849e078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:984a099a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:984a31c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:984a59e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:984a7f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:984aa332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:984ac704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:984aebee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:984b0ffc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:984b3824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:984b6038-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.221']} DrugCentral uuid:984b884c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.912']} DrugCentral uuid:984bb10a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:984bd4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:984bf8a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) DrugCentral uuid:984c1c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:984c45c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) DrugCentral uuid:984c6992-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:984c8de6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:984cb5e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.792']} DrugCentral uuid:984cde72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26281 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.75']} DrugCentral uuid:984d0e4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:984d0e4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:984d0e4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984d7f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:984e54fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63734 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is gating inhibitor of Ion channel (Potassium voltage-gated channel subfamily C member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:984e8042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioproperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:984ea914-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioproperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:984ed150-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:984ef518-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:984f1e62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:984f4720-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.872']} DrugCentral uuid:984f6f70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:984f978e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:984fbf7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:984fe842-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.813']} DrugCentral uuid:9850106a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:98503888-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:98506088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:985089e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9850b222-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9850da54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9851027c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:98512b30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.466']} DrugCentral uuid:98515362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:98517b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9851a3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9851cd4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.866']} DrugCentral uuid:9851f574-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:98521d9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:985245d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:98526e46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.595']} DrugCentral uuid:9852965a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:9852be82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:9852e6a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:98530f40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:9853375e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:98535f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.126']} DrugCentral uuid:98538826-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.774']} DrugCentral uuid:9853b210-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.751']} DrugCentral uuid:9853da1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:98540256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:98542ace-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:985452f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:98547c7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:9854a4a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9854ccf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:9854f63e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:98551e48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.195']} DrugCentral uuid:98554666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.297']} DrugCentral uuid:98556fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:985597ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:9855c046-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:9855e850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:9856110e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:98563936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:98566168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:98568968-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9856b1ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9856da1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9857114e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9857114e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9857114e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9857114e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9857114e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:98577224-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:98577224-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:98577224-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:98577224-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9857c418-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9857c418-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9857c418-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9858121a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9858121a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9858121a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9858121a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9858121a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:98586e5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:98586e5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:98586e5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9858b42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9858b42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9858b42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9858f284-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:98591c82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiotepa is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:985944b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:98596cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:98599518-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:9859bdea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:9859e5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:985a0e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:985a363a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:985a5e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.681']} DrugCentral uuid:985a869e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.817']} DrugCentral uuid:985aafb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:985ad7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:985b0132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:985b2950-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:985b518c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:985b7a54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:985ba27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:985bca9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:985bf2b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:985c1bbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:985c43d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:985c6bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:985c9402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.181']} DrugCentral uuid:985cbd88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:985ce5f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:985d0e0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:985d361e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:985d5ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:985d870e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) DrugCentral uuid:985daad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:985dd36c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:985dfbbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:985e2416-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:985e4c3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Unclassified (THAP domain-containing protein 1) DrugCentral uuid:985e6fe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:985e9a18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40926 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:985ec24a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine is inhibitor of Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:985eeb9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:985f13d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:985f3c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31651 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:985f6c4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:985f6c4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:985f6c4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:985fb272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:985fb272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:985fb272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:985ff142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tianeptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:98601956-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.077']} DrugCentral uuid:98604156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.108']} DrugCentral uuid:98606b2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.756']} DrugCentral uuid:98609520-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:9860bd52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9860e566-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:98610df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.317']} DrugCentral uuid:98613606-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:98615e1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:986181d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:9861a62c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:9861ce04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Enzyme (Steryl-sulfatase) DrugCentral uuid:9861f1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.123']} DrugCentral uuid:986219fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.542']} DrugCentral uuid:98624528-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:986280a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:986280a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:986280a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:986280a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:986280a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:986280a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:986280a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9862deac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:986306c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:98632ede-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:98635710-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.747']} DrugCentral uuid:98637fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:9863a814-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.767']} DrugCentral uuid:9863d154-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:9863f968-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9864235c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:98644b8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:98646f74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.175']} DrugCentral uuid:9864979c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9864c028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:9864e83c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:98651050-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tienilic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.494']} DrugCentral uuid:98653846-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tilidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:98656104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiliquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:986588fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:9865acae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13488 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (V-type proton ATPase 116 kDa subunit a isoform 3) DrugCentral uuid:9865d08a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9865fd08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:98662774-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:98664f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tinoridine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.987']} DrugCentral uuid:98667800-dc5e-11ec-be2c-0242ac110005 UniProtKB:O69638 biolink:molecularly_interacts_with DrugCentral:2673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiocarlide targets Enzyme (Epoxide hydrolase EphE; Hydrolase, alpha/beta hydrolase fold family) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9866a01e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2675 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:9866c3dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:2675 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9866ec04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiopronin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:986714b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:98673cb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:986764ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11.1']} DrugCentral uuid:98678cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:9867b652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:9867e078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:98680896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:986830aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:98685918-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1PT23 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:986881ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1PWR7 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.94']} DrugCentral uuid:9868a9cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:F1PGZ2 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:9868d1ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiracizine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9868fe86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:9868fe86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:986931bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:986959bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:98697ec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:9869a96c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9869d2ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:9869faca-dc5e-11ec-be2c-0242ac110005 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:986a2342-dc5e-11ec-be2c-0242ac110005 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:2684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tobramycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.824']} DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986a6e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:986ae9c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:986b11d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:986b39ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.292']} DrugCentral uuid:986b675c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:986b675c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:986b9506-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:986bbd38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:986be588-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:986c0e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:986c3650-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:986c6616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:986c6616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:986c6616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:986caca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:986caca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:986caca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:986cec1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:986d1444-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:986d4144-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:986d4144-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:986d747a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:986d9c8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:986dc5c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:986dee14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:986e16a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:986e3ebe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.569']} DrugCentral uuid:986e67ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:986e8fa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:986eb79a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:986edf90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:986f08f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:986f3346-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:986f5b50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:986f8364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:986fabb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:986fd3d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:986ffbb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.667']} DrugCentral uuid:987023aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:2701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolonium targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:98704c40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:2701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolonium targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:98707436-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:98709d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9870c594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9870ee66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:987116ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:98713ee8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:9871672e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:98718fc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70634 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Unclassified (SMR1-alpha3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:9871b7d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70635 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Unclassified (BetaB2-crystallin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.474']} DrugCentral uuid:9871dff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:98720800-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:987230a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:987258aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:987280aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9872a92c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9872d276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9872fa94-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:987322bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.509']} DrugCentral uuid:98734b3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9873735c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:98739b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:9873c4f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:9873ed64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:9874160e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:98743e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:9874662c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:98749016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9874b85c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:9874e066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:987508a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:98752cf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:987550aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:98757468-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:98759c90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9875c51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9875ed58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:98761580-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:98763dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:98766710-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:98768f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9876b724-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:9876df2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:987707ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:98773014-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:98775828-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:98778078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:9877a8be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27139 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9877d0b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9877f8be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.63']} DrugCentral uuid:987820dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:98784b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:98787370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:98789c6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9878c53c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9878ed50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9879155a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:98793dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:98796690-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:98798fe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9879b80c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9879e034-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:987a09ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:987a398a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:987a398a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:987a398a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:987a7490-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:987a7490-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:987ab7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:987ab7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:987ab7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:987ab7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:987ab7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:987b0dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:987b0dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:987b0dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:987b0dd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:987b4f28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:987b775a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:987b9f82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.818']} DrugCentral uuid:987bc778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:987bee56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:987c1214-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:987c35c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:987c5986-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:987c7dee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan is inhibitor of Enzyme (DNA topoisomerase I, mitochondrial) DrugCentral uuid:987ca1b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.58']} DrugCentral uuid:987cc9ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:987cf1de-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:987d1a4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:987d4288-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:987d6a88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04750 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (DNA topoisomerase I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:987d9288-dc5e-11ec-be2c-0242ac110005 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:987dbbaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:987de3be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 torsemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:987e0bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:987e3404-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene is modulator of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:987e59a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets Nuclear hormone receptor (Estrogen-related receptor gamma) DrugCentral uuid:987e7d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05320 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets Unclassified (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:987ea59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:987ece6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:987ef6c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:987f1edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:987f46f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:987f6f0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:987f9a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:987fc35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trandolapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:987feb8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranexamic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:988014a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranilast targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:98803d3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:9880653a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:98808db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:9880b652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:9880de84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:98810698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:98812f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:988158be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:988180be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:9881a8d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:9881d0f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:9881f990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9882217c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:988249a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:988271b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NB78 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:98829a26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9882c23a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 travoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:9882ea62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 travoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:9883126c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:98833c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:98836492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:98838c9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.033']} DrugCentral uuid:9883b49c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9883dd5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:98840672-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98842fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:988457da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:98848070-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9884a8a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:9884d0c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:9884f96a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.551']} DrugCentral uuid:9885230e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:98854b22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:98857322-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:98859bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.483']} DrugCentral uuid:9885c3d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:9885ebcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:988613f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:98863c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:98866462-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:98868c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:9886b48a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.081']} DrugCentral uuid:9886dd66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.083']} DrugCentral uuid:9887057a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:98872d70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:988755ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:98877e4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9887a67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9887cea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9887f7b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:98882086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9888489a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:988870ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:988898b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9888c306-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.642']} DrugCentral uuid:9888eb2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:98891338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:98893b2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:988963a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:98898bba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9889b3ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9889dca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:988a05ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:988a2e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:988a569e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:988a8006-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92753 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is antagonist of Nuclear hormone receptor (Nuclear receptor ROR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:988aaa7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:988ad2a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:988afaa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:988b231c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:988b4b3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:988b7358-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62965 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:988b9b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22935 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:988bc538-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:988bed4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:988c1556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:988c3d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:988c6754-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:988c8f86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:988cb768-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:988cdf86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13526 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Unclassified (Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:988d07f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:988d2ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:988d57fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:988d8026-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:988da8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:988dd0da-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.76']} DrugCentral uuid:988e006e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:988e006e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:988e006e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:988e5032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:988e5032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:988e5032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:988e5032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:988e5032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:988eb75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:988eb75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:988eb75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:988eb75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:988eb75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:988eb75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:988f219c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:988f219c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:988f219c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:988f60c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:988f88ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone targets Cytosolic other (Annexin A1) DrugCentral uuid:988facac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:988fd088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:988ff978-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide targets Cytosolic other (Annexin A1) DrugCentral uuid:98901dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:9890461c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:989069da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Transporter (Solute carrier family 12 member 1) DrugCentral uuid:98908e10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9890b674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:9890de6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:98910674-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:989136da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:989136da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:989136da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9891751e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:98919d82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.879']} DrugCentral uuid:9891c5aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:9891f67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:9891f67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:9891f67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:98923f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:98923f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:98923f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:98928652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:98928652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:98928652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:9892cc8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:9892cc8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:9892cc8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:9893136a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:9893136a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:9893136a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:98935abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:98935abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:98935abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9893d3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9894d196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:98958816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:98958816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:98958816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:9895cf88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:9895cf88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:9895cf88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:989617ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:989617ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:989617ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:98965e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:98965e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:98965e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:9896a444-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9896a444-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9896a444-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9896e3a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:98970bb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7']} DrugCentral uuid:989733aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:98975cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:98978530-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9897ad62-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9897d60c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9897ff60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:9898277e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:98984f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:989877ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9898a12c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9898c968-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclabendazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:98992b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:9899e2a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:989a0698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:989a2a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:989a5288-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:989a7b1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:989aa332-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:989acb64-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:989af49a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:989b2028-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.31']} DrugCentral uuid:989b4864-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:989b7096-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:989b99fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:989bc244-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:989bea6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:989c12b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:989c3b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.841']} DrugCentral uuid:989c638e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:989c8bca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:989cb410-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:989cde04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:989d0640-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:989d2e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:989d56a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:989d7f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:989da762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:989dcf8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:989df7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:989e2034-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.786']} DrugCentral uuid:989e48fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.251']} DrugCentral uuid:989e712e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:989e9960-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:989ec494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:989eecbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:989f1c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:989f1c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:989f1c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:989f5d50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:989f8578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.27']} DrugCentral uuid:989fada0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:989fd73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:989fffb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:98a027ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06760 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Beta-glucuronidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:98a0500c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00697 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Lysozyme C-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:98a07956-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:98a0a1b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:98a0c9ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:98a0f9b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:98a0f9b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:98a0f9b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:98a1402a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:98a1402a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:98a1402a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:98a185f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:98a185f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:98a185f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:98a1c4fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:98a1ed0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:98a21536-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:98a23d68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:98a26680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:98a28eb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:98a2b7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:98a2e042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:98a30892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:98a330e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:98a3590a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:98a38204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:98a3aa4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:98a3d27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:98a3faa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2743 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:98a42416-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2743 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.01']} DrugCentral uuid:98a44edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:98a47844-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:98a4a076-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.73']} DrugCentral uuid:98a4c8e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:98a4f116-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:98a51934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:98a5415c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.611']} DrugCentral uuid:98a56a2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26439 biolink:molecularly_interacts_with DrugCentral:2746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilostane is inhibitor of Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2) DrugCentral uuid:98a58e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alimemazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:98a5b1c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alimemazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:98a5d9b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2750 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetazidine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:98a602d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethadione is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:98a626a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:98a64a66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) DrugCentral uuid:98a66e2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:98a696b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:98a6c3ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:98a6c3ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:98a6f150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:98a71982-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:98a74272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:98a76ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:98a792cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27713 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:98a7baea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:98a7e696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:98a80ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:98a8383a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:98a860b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:98a888e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:98a8b10c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:98a8d92a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:98a90210-dc5e-11ec-be2c-0242ac110005 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:98a92a2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:98a952ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:98a97af6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:98a9a404-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:98a9cc18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04174 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:98a9f42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59487 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:98aa1d6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:98aa460c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27552 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:98aa6e20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:98aa974c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:98aabf92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q54801 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:98aae85a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UUP5 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:98ab1078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:98ab38a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:98ab5c72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:98ab8760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:98abafe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:98abd814-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:98ac001e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:98ac28a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:98ac50c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:98ac78e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:98aca122-dc5e-11ec-be2c-0242ac110005 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:98acc9f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:98acf212-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:98ad1a62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:98ad437a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:98ad6c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:98ad9456-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.423']} DrugCentral uuid:98adbc9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:98ade51e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:98ae0d82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:98ae35b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:98ae5dd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:98ae878a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:98aeafda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:98aed898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tripelennamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:98af00ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triprolidine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:98af29d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triprolidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.9']} DrugCentral uuid:98af5214-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.208']} DrugCentral uuid:98af7a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.078']} DrugCentral uuid:98afa282-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:98afcb18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:98aff462-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:98b01c8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:98b044bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:98b06d8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:98b095c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Aldose reductase) DrugCentral uuid:98b0b988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:98b0e192-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:98b10bea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54840 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Glycogen [starch] synthase, liver) DrugCentral uuid:98b12fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:98b157f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:98b18020-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.907']} DrugCentral uuid:98b1a906-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:98b1d138-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:98b1f96a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:98b2219c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:98b24a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:98b2725a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:98b29b72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:98b2c49e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2769 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troleandomycin is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:98b2eff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:98b319a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:98b341e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:98b36aac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:98b392de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:98b3bb1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:98b3e342-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:98b40bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:98b433e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:98b45c1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:98b48450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:98b4aea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:98b4d6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:98b4ff0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:98b5272a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:98b54ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:98b57806-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:98b5a042-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:98b5c96e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:98b5f20e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:98b61a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70212 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:98b64646-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:98b64646-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:98b67f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:98b67f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:98b6be3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:98b6be3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:98b6be3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:98b6be3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:98b70c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:98b70c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:98b73fb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:98b767e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:98b7901e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:98b7b896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:98b7dc68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:98b8003a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:98b823e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:98b848ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.306']} DrugCentral uuid:98b8710a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.395']} DrugCentral uuid:98b89cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:98b89cf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:98b8ce5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:98b8ce5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:98b8fc92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan is allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:98b92488-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:98b94c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:98b97488-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:98b99cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:98b9c4d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:98b9eddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:98ba16f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:98ba3f94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2S1 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:98ba67c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:98ba8fe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:98bab92e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q401N2 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Zinc-activated ligand-gated ion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:98bae278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:98bb0aaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:98bb32dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:98bb5b68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:98bb8386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:98bbabae-dc5e-11ec-be2c-0242ac110005 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:98bbd7c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:98bbd7c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:98bc171a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:98bc171a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:98bc171a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:98bc5a72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:98bc5a72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:98bc921c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:98bc921c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:98bcc94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:98bcc94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:98bd004e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:98bd004e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:98bd40b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98bd40b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98bd40b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98bd40b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98bd8e10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:98bd8e10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:98bdc2b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98be25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98bef688-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:98bf1ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tulobuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:98bf46ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tulobuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:98bf6a96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:98bf9390-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.7']} DrugCentral uuid:98bfbdde-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:98bfe5de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:98c00dd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c06770-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:98c11ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:98c14708-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyrosine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:98c1702a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:98c19816-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15144 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:98c1c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28838 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:98c1e9ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:98c21264-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15145 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:98c23a8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96935 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (M1 family aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:98c26296-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VCT3 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:98c28a8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97629 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Leucyl-cystinyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:98c2b408-dc5e-11ec-be2c-0242ac110005 UniProtKB:O09175 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:98c2dc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00727 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:98c30444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97449 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:98c32c62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:98c35552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:98c37d5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15684 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:98c3a566-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55786 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Puromycin-sensitive aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:98c3cd52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:98c3f5de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ08 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Endoplasmic reticulum aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:98c41dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:98c445f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:98c46e1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:98c496a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:98c4beb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Enzyme (Aldo-keto reductase family 1 member C2) DrugCentral uuid:98c4e296-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol is agonist of Nuclear hormone receptor (Bile acid receptor) DrugCentral uuid:98c50654-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:98c52ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:98c55712-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:98c57f3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valaciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:98c5a30c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:98c5cc92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:98c5f49c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.537']} DrugCentral uuid:98c61cba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:98c644e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:98c66d64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:98c6958c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:98c6bdaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:98c6e6ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:98c70f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:98c73730-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:98c75f58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:98c7885c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:98c7b08e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:98c7d8a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:98c800c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:98c8292e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:98c8514c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:98c87960-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:98c8a2aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:98c8cbe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:98c8f3fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:98c91c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:98c94444-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:98c96d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:98c99598-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:98c9bea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:98c9e6b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:98ca0f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:98ca378c-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:98ca5fa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:98ca87c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:98cab392-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:98caddb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:98cb05b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:98cb2e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:98cb5658-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:98cb7e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:98cba6b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:98cbcf70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:98cbf798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:98cc1fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:98cc47de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:98cc710a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:98cc9928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:98ccbd72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51649 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid is inhibitor of Enzyme (Succinate-semialdehyde dehydrogenase, mitochondrial) DrugCentral uuid:98cce130-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:98cd096c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:98cd3180-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:98cd596c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:98cd8180-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:98cdaa16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:98cdd306-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:98cdfae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35504 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (UDP-glucuronosyltransferase 1-5) DrugCentral uuid:98ce1ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5RJP0 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase-related protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:98ce4796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valrubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:98ce6b86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:98ce94da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:98cebd02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:98cee958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:98cee958-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:98cf1c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:98cf44ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06241 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets Enzyme (D-alanyl-D-alanine dipeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:98cf6cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17443 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets Enzyme (UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:98cf957e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:98cfbd92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:98cfe98e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:98cfe98e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:98d0217e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:98d0217e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:98d05892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:98d05892-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:98d08f88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:98d08f88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:98d0c78c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:98d0c78c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:98d0feb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:98d0feb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:98d136cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:98d136cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:98d16e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:98d16e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:98d1acf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:98d1acf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:98d1acf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:98d1acf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:98d1fb84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:98d1fb84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:98d23a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:98d23a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:98d23a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:98d23a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:98d2841e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:98d2ac1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.465']} DrugCentral uuid:98d2d554-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:98d2fd40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.041']} DrugCentral uuid:98d32644-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:98d34e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:98d3764e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:98d3a222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:98d3a222-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:98d3e430-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:98d3e430-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:98d3e430-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:98d3e430-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:98d4312e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:98d4312e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:98d4650e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:98d48d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:98d4b59a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:98d4ddc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:98d5063a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32307 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:98d52e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:98d55658-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:98d57e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48044 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:98d5a8ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:98d5d0d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:98d5fcd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:98d5fcd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:98d630a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:98d658b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:98d680be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:98d6ac88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:98d6ac88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:98d6e23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:98d6e23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:98d6e23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:98d72564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:98d72564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:98d7569c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:98d7569c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:98d7929c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98d7929c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98d7929c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98d7929c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:98d7dd6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.051']} DrugCentral uuid:98d80632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:98d82e50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.652']} DrugCentral uuid:98d85664-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:98d87e78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.554']} DrugCentral uuid:98d8a704-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:98d8cf0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:98d8f718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:98d91f36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:98d948ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:98d97120-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:98d9992a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:98d9bce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:98d9e592-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:98da0da6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:98da35d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:98da5e00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:98da866e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.763']} DrugCentral uuid:98daafc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:98dad7f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:98db001c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:98db2b28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:98db533c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.594']} DrugCentral uuid:98db7b50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:98dba3c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:98dbcc0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:98dbf42c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:98dc1c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:98dc447c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:98dc6826-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (G protein-activated inward rectifier potassium channel 2) DrugCentral uuid:98dc8be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.485']} DrugCentral uuid:98dcb42a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) DrugCentral uuid:98dcd7fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:98dd0286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:98dd2bb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96PR1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:98dd53b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:98dd7c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.348']} DrugCentral uuid:98dda47a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:98ddcc8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:98ddf4de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:98de1d42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:98de4560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:98de6d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:98de9664-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:98dec01c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:98deeb3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:98df156c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:98df3d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.071']} DrugCentral uuid:98df6e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:98df6e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:98df6e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:98dfb44a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:98dfb44a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:98dfb44a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:98dff2e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:98e01b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:98e0432e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:98e06b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULQ1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:98e094fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NHX9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:98e0bf16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:98e0e72a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:98e10f34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:98e13b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:98e13b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:98e16e98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Transitional endoplasmic reticulum ATPase) DrugCentral uuid:98e19288-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:98e1b63c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:98e1da86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:98e1ff20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:98e222d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:98e24692-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16854 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Deoxyguanosine kinase, mitochondrial) DrugCentral uuid:98e26c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:98e292be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:98e2bad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04400 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Adenylate cyclase type V) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:98e2e2fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50247 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:98e30b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80404 biolink:molecularly_interacts_with DrugCentral:2819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vigabatrin is inhibitor of Enzyme (4-aminobutyrate aminotransferase, mitochondrial) DrugCentral uuid:98e32f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50554 biolink:molecularly_interacts_with DrugCentral:2819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vigabatrin targets Enzyme (Gamma-amino-N-butyrate transaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:98e35780-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.76']} DrugCentral uuid:98e37f9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:98e3a884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:98e3d098-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:98e3f8c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:98e420e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine is antagonist of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:98e44a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:98e4725a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:98e49618-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:98e4b9d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:98e4de20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.728']} DrugCentral uuid:98e50634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.298']} DrugCentral uuid:98e52e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e57678-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:98e5f8aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:98e622f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:98e64b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:98e67366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:98e69b84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:98e6bfb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:98e6e35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:98e70704-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:98e73260-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:98e73260-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:98e73260-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e7916a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e80618-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vindesine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.607']} DrugCentral uuid:98e82e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:98e8564a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e89d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:98e90fd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:98e93876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:98e96094-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine is inhibitor of Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:98e98c9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:98e98c9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:98e9c192-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (11-cis retinol dehydrogenase) DrugCentral uuid:98e9e6fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NR8 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 12) DrugCentral uuid:98ea0a9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NBN7 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 13) DrugCentral uuid:98ea2e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10745 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Surface antigen (Retinol-binding protein 3) DrugCentral uuid:98ea5256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P82980 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 5) DrugCentral uuid:98ea75f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96R05 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinoid-binding protein 7) DrugCentral uuid:98ea99b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:98eac1be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50120 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 2) DrugCentral uuid:98eae554-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94788 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 2) DrugCentral uuid:98eb0976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00352 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 1) DrugCentral uuid:98eb2d16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12271 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Transporter (Retinaldehyde-binding protein 1) DrugCentral uuid:98eb51f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:98eb7a00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09455 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 1) DrugCentral uuid:98eb9fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:98ebc7a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60779 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Transporter (Thiamine transporter 1) DrugCentral uuid:98ebebde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29401 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Transketolase) DrugCentral uuid:98ec0f88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3S4 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Kinase (Thiamin pyrophosphokinase 1) DrugCentral uuid:98ec338c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BU02 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Thiamine-triphosphatase) DrugCentral uuid:98ec581c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51854 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Transketolase-like protein 1) DrugCentral uuid:98ec7be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:98eca40c-dc5e-11ec-be2c-0242ac110005 UniProtKB:A2RI47 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Transporter (Thiamine transporter ThiT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.91']} DrugCentral uuid:98eccca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30043 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Enzyme (Flavin reductase (NADPH)) DrugCentral uuid:98ecf060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969G6 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Kinase (Riboflavin kinase) DrugCentral uuid:98ed141e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:98ed3c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:98ed65cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:98ed8bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:98edaf78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinamide phosphoribosyltransferase) DrugCentral uuid:98edd32c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80Z39 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:98edfba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EP66 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:98ee23b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:98ee4be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:98ee73f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:98ee985c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NVS9 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Pyridoxine-5'-phosphate oxidase) DrugCentral uuid:98eebc06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD0 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Pyridoxal phosphate phosphatase) DrugCentral uuid:98eedfc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00764 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Kinase (Pyridoxal kinase) DrugCentral uuid:98ef036e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35520 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Cystathionine beta-synthase) DrugCentral uuid:98ef270e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y617 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Phosphoserine aminotransferase) DrugCentral uuid:98ef4df6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:98ef722c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:98ef95e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:98efb994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:98efe25c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:98f00642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:98f02e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:98f051e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02318 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (Sterol 26-hydroxylase, mitochondrial) DrugCentral uuid:98f07636-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydrotachysterol targets Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:98f099fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:98f0c3de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:98f0ebfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:98f114ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:98f13ce2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:98f164ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:98f18d1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['8.73']} DrugCentral uuid:98f1b5aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:98f1dda0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:98f205a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['5.844']} DrugCentral uuid:98f22dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:98f25712-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:98f27f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:98f2a71c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:98f2cf30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6A2 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cholesterol 24-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:98f2faa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.98']} DrugCentral uuid:98f3230e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.867']} DrugCentral uuid:98f34b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:98f373a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:98f39bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N0U8 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Vitamin K epoxide reductase complex subunit 1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.284']} DrugCentral uuid:98f3c3e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.75']} DrugCentral uuid:98f3ec1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:98f41502-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:98f43d16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:98f46516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:98f48d16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:98f4b796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:98f4e054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08709 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor VII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:98f50872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:98f53072-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:98f558d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03951 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor XI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:98f580e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:98f5a908-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:98f5d126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.873']} DrugCentral uuid:98f5f9ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.114']} DrugCentral uuid:98f62202-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:98f64a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:98f67266-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytosolic phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:98f69c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:98f6c572-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:98f6ed72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.419']} DrugCentral uuid:98f71590-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.359']} DrugCentral uuid:98f73e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:98f76644-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.452']} DrugCentral uuid:98f78e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:98f7b66c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:98f7e006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.269']} DrugCentral uuid:98f8081a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:98f8320e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:98f85b6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:98f884ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:98f8adec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:98f8d704-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:98f90008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:98f92808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zalcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:98f94be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zalcitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:98f97bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:98f97bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:98f97bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:98f9c27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:98f9c27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:98f9c27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:98fa00d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:98fa29c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:98fa52be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:98fa7af0-dc5e-11ec-be2c-0242ac110005 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:98faa2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:98facbfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:98faf408-dc5e-11ec-be2c-0242ac110005 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:98fb1c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:98fb443a-dc5e-11ec-be2c-0242ac110005 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:98fb6ca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:98fb94a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:98fbc18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:98fbe994-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ49 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:98fc12a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:98fc3cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:98fc64d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3S340 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:98fc8d90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WWR8 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:98fcb72a-dc5e-11ec-be2c-0242ac110005 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:98fcdf48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:98fd075c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:98fd2f70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:98fd58b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:98fd80ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:98fda900-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23919 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:98fdd11e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:98fdfbe4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:98fe24de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:98fe50da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:98fe798e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:98fea198-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:98fec9b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9PPP5 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:98fef1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:98ff1b00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:98ff431e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:98ff6b32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:98ff9332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:98ffbcfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:98ffe526-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:99000d26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:99003530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:99005eca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:99008774-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9900af88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:9900d79c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:9901000a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:990132fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9901613a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:99018a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:9901b270-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:9901db24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:99020338-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:99022bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9902557c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:99027e80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:9902a6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9902cf48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.565']} DrugCentral uuid:9902f784-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:99031fa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:990347d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:99037240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:99039a54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:9903c27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:9903eaa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:99041358-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:99043b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:990464b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:99048d4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:9904b57e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9904dd9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:990505ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:99052f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9905598e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:990581ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:9905ae48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:9905d2ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9905fb00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9906233c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:99064b6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:9906747c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:99069cb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9906c4d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9906ecf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99071760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:99073f92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:990767b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:99079802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99079802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99079802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9907d70e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9907ff36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:99082d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:990856ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:99087ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9908a79c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9908d0be-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9908f9f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:99092244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:99094a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:990977ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9909a0a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9909c94c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9909f156-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:990a19ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:990a45b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:990a6de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:990a95fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:990ac04a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00481 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Unclassified (Butyrophilin subfamily 3 member A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:990ae822-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:990b10fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:990b396c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:990b6248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:990b8eda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:990bb70c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:990bdf8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:990c0f5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:990c0f5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:990c0f5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:990c4f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:990c77be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:990ca0b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:990cc8cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.703']} DrugCentral uuid:990cf0f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:990d1a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:990d42ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:990d6af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:990d9acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:990d9acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:990d9acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:990de27a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:990de27a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:990de27a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:990e2938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:990e2938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:990e2938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:990e714a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:990e714a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:990e714a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990eee72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:990fc644-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:990fc644-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:990fc644-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:99100c44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:99100c44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:99100c44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:99105938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:99105938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:99105938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:99109f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:99109f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:99109f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:9910e862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:9910e862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:9910e862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:991126c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:99114eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:9911773c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:9911a324-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9911a324-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9911d650-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:9911fb62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:9912238a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:99124734-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:99126f52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9912986a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9912c07e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9912e89c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:991310c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:99133928-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9913613c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:99138950-dc5e-11ec-be2c-0242ac110005 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9913b16e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9913dafe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:99140312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:99142b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9914536c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:99147d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9914a5a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:9914cdd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9914f614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:99151e82-dc5e-11ec-be2c-0242ac110005 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:991546a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:99156ec8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:991596f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9915c116-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9915e948-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:99161184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:99163eca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:99163eca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:99167390-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:99169bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6NSN2 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:9916c3d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:9916ec4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:99171476-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:99177614-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:991855d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:991855d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:991855d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:99189c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:99189c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:99189c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:9918e2ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:9918e2ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:9918e2ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:991928c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:991928c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:991928c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:9919702c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:9919702c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:9919702c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:9919b7f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9919b7f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9919b7f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9919feca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:9919feca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:9919feca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:991a44c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:991a44c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:991a44c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:991a837c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.394']} DrugCentral uuid:991aaba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:991ad3c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:991afbea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:991b2548-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:991b4f82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:991b7796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:991b9fa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:991bc836-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:991bf068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:991c1886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:991c40ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:991c6912-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:991c9126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.273']} DrugCentral uuid:991cb94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:991ce18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.606']} DrugCentral uuid:991d0c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:991d3450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:991d5c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.704']} DrugCentral uuid:991d8482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:991dadae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:991dd5b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:991dfdcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:991e25f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:991e4e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:991e76c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:991e9ee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:991ec78e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:991ef1aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:991f1af4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:991f4312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:991f6bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:991f93f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:991fbc2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:991fe43e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:99200cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:992030c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:992058ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:99207cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:9920a1a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:9920c7a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) DrugCentral uuid:9920eb72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9921148a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:99213d20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotarolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:99216534-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotarolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:99218d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eledoisin is agonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9921b566-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:2955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eledoisin targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:9921de1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:99220638-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:99222e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16235 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:99225e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:99225e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:99225e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:99229828-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifamurtide is activator of Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) DrugCentral uuid:9922bbf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9922e3fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['4']} DrugCentral uuid:99230c22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9923349a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99235c9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:99238512-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9923adda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9923d94a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:99240168-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9924297c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:992452bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:99247ada-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.749']} DrugCentral uuid:9924a30c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15648 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (ATP-dependent 6-phosphofructokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9924f276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:99258ac4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:9925b2ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:9925dae2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80Z26 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Nucleoside triphosphate diphosphohydrolase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:99260300-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35795 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Ectonucleoside triphosphate diphosphohydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:99262c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49654 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:99265490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:99267c9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47824 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9926a4a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9926cd1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42224 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 1-alpha/beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:9926f558-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42229 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:99271d6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51692 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:99274580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.025']} DrugCentral uuid:99276e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:99279634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:9927b9de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:9927e616-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:9927e616-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:9927e616-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:99282446-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histrelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:99284822-dc5e-11ec-be2c-0242ac110005 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9928704a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4WLT4 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin is inhibitor of Enzyme (1,3-beta-glucan synthase catalytic subunit FksP) DrugCentral uuid:9928950c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O13383 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin targets Unclassified (1,3-beta-D-glucan synthase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:9928c108-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:9928c108-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:9928f826-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:9928f826-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:99292fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:99292fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:9929641e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.086']} DrugCentral uuid:99298c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['12.7']} DrugCentral uuid:9929b4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9929ddea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:992a05e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30082 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992a4a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:992ac1ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:F8V479 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:992ae9e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35659 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.36']} DrugCentral uuid:992b12d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lepirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['13']} DrugCentral uuid:992b3af0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:992b6304-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:992b8b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:992bb476-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:992bdc76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:992c1394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:992c1394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:992c1394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:992c1394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:992c1394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:992c7870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:992c7870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:992c7870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:992c7870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:992c7870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:992cccee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.46']} DrugCentral uuid:992cf606-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:992d1e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:992d466a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:992d6fe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:992d9976-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96529 biolink:molecularly_interacts_with DrugCentral:2999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrantel targets Enzyme (Acetylcholinesterase) DrugCentral uuid:992dbd52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:992de57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:992e0f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:992e3796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:992e5fdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban is antagonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:992e87fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:992eb478-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:992eb478-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:992eb478-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:992ef2d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.934']} DrugCentral uuid:992f1b02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:992f4474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:992f6cf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:992f951e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:992fbd46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:992fe654-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.532']} DrugCentral uuid:99300efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.004']} DrugCentral uuid:99303712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:99305f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.092']} DrugCentral uuid:9930883e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:9930b066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:9930d87a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:99310098-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:99312ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.649']} DrugCentral uuid:993152dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.115']} DrugCentral uuid:99317af0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.681']} DrugCentral uuid:9931a2fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.192']} DrugCentral uuid:9931cc8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:9931f4a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969F8 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (KiSS-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:99321cbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:993244bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:993272c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:99329ade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9932c2fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:9932ebc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:993314aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.299']} DrugCentral uuid:99333dd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.651']} DrugCentral uuid:993365f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:99338e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:9933b6b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:9933ded0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.501']} DrugCentral uuid:993406e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:99342fac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:993457c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:99347ff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.844']} DrugCentral uuid:9934a7fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:9934d1aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.761']} DrugCentral uuid:9934f9d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9935220e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:99354acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:99357358-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.212']} DrugCentral uuid:99359b58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.647']} DrugCentral uuid:9935c466-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:9935ec66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.735']} DrugCentral uuid:99361524-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.498']} DrugCentral uuid:99363d60-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:99366574-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:99368d9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.415']} DrugCentral uuid:9936b7f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9936e01c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:99370830-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9937304e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:99375b32-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9937833c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:9937aba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9937d468-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9937fc72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:99382486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:3042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:99384cae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:3042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxuridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9938763e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.97']} DrugCentral uuid:9938a078-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.91']} DrugCentral uuid:9938c8a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9938f0b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:993920c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:993920c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:993920c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9939683c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:9939683c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:9939683c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:9939a888-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9939d0ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9939f8d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:993a20d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:993a49fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:993a7218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54577 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Tyrosine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:993a9a40-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:993ac272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03887 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Unclassified (NADH-ubiquinone oxidoreductase chain 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:993aeb6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:993b1394-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q704Y3 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is activator of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:993b3ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:993b63bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:993b8c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:993bb4a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:993bdcac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:993c04ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:993c2e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NJH6 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Unclassified (Ace-orthologous acetylcholinesterase; Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:993c5646-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7YWJ9 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:993c7e78-dc5e-11ec-be2c-0242ac110005 UniProtKB:K4JQ36 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:993ca68c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:3067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbon tetrachloride targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:993ccf86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31327 biolink:molecularly_interacts_with DrugCentral:3068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carglumic acid is positive allosteric modulator of Enzyme (Carbamoyl-phosphate synthase [ammonia], mitochondrial) DrugCentral uuid:993cfb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:993cfb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:993cfb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:993d3a66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:3082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrimonium targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:993d634c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetylpyridinium targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:993d8b6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42575 biolink:molecularly_interacts_with DrugCentral:3083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetylpyridinium targets Enzyme (Caspase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:993db3c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxylenol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:993ddbf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxylenol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.738']} DrugCentral uuid:993e05b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:3095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorquinaldol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:993e2dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:993e55fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:3096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:993e7e12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:993ea7ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:993ed3c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:993ed3c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:993f0ac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:993f0ac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:993f42c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:993f42c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:993f79d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:993f79d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:993fb0ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:993fb0ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:993fe586-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:99400dcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.9']} DrugCentral uuid:994036ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:3102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinromide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99406006-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9940881a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9940b024-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:9940d838-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9941086c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9941086c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9941086c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:994146ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cynarine targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99416eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demoxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9941a48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9941a48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9941a48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9941a48e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9941f0c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:99421496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99423d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:99426536-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:99428dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9942b5fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 difluprednate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9942e1fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9942e1fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9942e1fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:99432048-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:9943497e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:99437412-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxadrol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:99439c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9943c480-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9943ecbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:3165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:99441552-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30987 biolink:molecularly_interacts_with DrugCentral:3165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:99443d98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:994465b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:99448dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9944b66a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9944de92-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:3173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edoxudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9945067e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:99452eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99455804-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99458040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9945a872-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9945d09a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9945f930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:99462162-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:99464a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9946723e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:99469ab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enilconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:9946c2e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:9946eb06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:9947148c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9947404c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9947687e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.91']} DrugCentral uuid:994790a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:9947b928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:9947e150-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:99480978-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:994831b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:99485a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16232 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:99488254-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50233 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9948aa68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9948d286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:9948fbc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:9949252e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:99494d60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9CPU0 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9949759c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:99499e0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9949c61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:9949ee3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:994a1664-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.748']} DrugCentral uuid:994a3f18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:994a6754-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:994a8f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:994ab7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:994ae0b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.064']} DrugCentral uuid:994b08e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:994b3206-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:994b5a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:994b8346-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.062']} DrugCentral uuid:994bab96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:994bd3be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:994bfc2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:994c244a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:994c4c68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:994c7486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:994c9da8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:994cc5c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:994cee02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:994d162a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:994d3eac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacridine targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:994d66ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:3194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacridine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:994d8ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:994db710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:994ddfb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:994e07ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:994e3000-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:994e581e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:994e82bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:994eaaee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:994ed32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:994efb5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:994f25dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:994f4e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:994f7640-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:994f9ed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:994fc712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:994fef44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:99501780-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01812 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:995040ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:995068e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:99509c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:99509c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:99509c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:99509c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9950f61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:9950f61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:9950f61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:9950f61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:9950f61e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:995151e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:995151e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:995151e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9951a7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9951a7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9951a7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9951a7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9951a7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9951a7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9951a7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:995214d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:99523d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:99526558-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:99528d9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13822 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9952b60c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9952de3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.217']} DrugCentral uuid:9953065c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:99532ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.859']} DrugCentral uuid:99535710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:99537f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:9953a896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:9953d0c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.641']} DrugCentral uuid:9953fa94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.377']} DrugCentral uuid:995422c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:99544aee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:9954730c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:99549b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.328']} DrugCentral uuid:9954c3ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:9954ebd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.688']} DrugCentral uuid:995513f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:99553c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:995564ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:3224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendosal is inhibitor of Secreted (Plasminogen activator inhibitor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:99558de6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoxazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9955b726-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04303 biolink:molecularly_interacts_with DrugCentral:3227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenticlor targets Enzyme (Uracil-DNA glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:9955dff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:3229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fumaric acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:99560820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:99563066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:995658e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:99568516-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:99568516-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:9956dff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:995777aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fumagillin targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:9957a144-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9957c96c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9957f176-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:99581ac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:995843ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:99586bf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:9958950e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9958bd4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9958e5ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:99590e08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:9959361c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:99595e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9959877a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9959af98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:9959d7a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:995a002e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:995a2842-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:995a506a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:995a78a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:995aa132-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:995ac95a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:995af178-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:995b19aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:995b43da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:995b6e0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:995b961e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:995bbe32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:995be6c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:995c0edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:995c36e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:995c5efa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:995c877c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:995cb080-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:995cd894-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:995d00bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:995d2c40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:995d56de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:995d7f06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:995da814-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:995dd01e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:995df850-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:995e21ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:995e4a30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.89']} DrugCentral uuid:995e7262-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:995e9a6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:995ec276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:995eec56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:995f1654-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:995f3e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:3293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibufenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:995f6690-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:995f8f12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.969']} DrugCentral uuid:995fb726-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:995fdf4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9960074e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:99602fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.181']} DrugCentral uuid:996057f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.859']} DrugCentral uuid:99608016-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.227']} DrugCentral uuid:9960a91a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:9960d3cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9960fbfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9961241c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:99614c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:996174da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.496']} DrugCentral uuid:99619cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:9961c516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9961ed98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:996215ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:99623db6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:996265ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:99628f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:9962b732-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:9962df3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:99630750-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:99632fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:996357b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:99637fdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9963a7f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9963d05e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9963f99e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:996421b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:996449c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:99647ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:99647ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:99647ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9964bc26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:3309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9964e43a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:99650cb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:996534da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:99655d02-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9965852a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9965adb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:9965d1ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9965fa32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 khellin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:99662246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:99664c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:996674d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:99669d2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:9966c53e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9966edca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:996715e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99673e1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9967664c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:99678ec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9967b70a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9967df28-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9968087c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14721 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is activator of Ion channel (Potassium voltage-gated channel subfamily B member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:99683234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:99685a5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:996882a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:9968ab24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:9968d36a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9968fbc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lodoxamide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.793']} DrugCentral uuid:996923f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:3328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubeluzole targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:99694c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:3328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubeluzole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:996974b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestanolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:996999bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.81']} DrugCentral uuid:9969c202-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesterolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.6']} DrugCentral uuid:9969ebe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesterolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:996a140a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O34667 biolink:molecularly_interacts_with DrugCentral:3347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methionine targets Unclassified (S-ribosylhomocysteine lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:996a3c3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.077']} DrugCentral uuid:996a648c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:996a8cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:996ab522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:996add2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:996b054a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:3362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoguazone targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:996b2dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36633 biolink:molecularly_interacts_with DrugCentral:3362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoguazone targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:996b59b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:996b59b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:996b8d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:996bb710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:996be15e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:996c0a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:996c32d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:996c6386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996c6386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996c6386-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996ca9c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:996ca9c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:996ca9c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:996cfb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996cfb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996cfb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996cfb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996cfb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996cfb7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:996d5b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:3377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neridronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:996d8400-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifenalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.88']} DrugCentral uuid:996daf20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:996dd914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:996e0100-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:996e2950-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:996e5150-dc5e-11ec-be2c-0242ac110005 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:996e7a7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01705 biolink:molecularly_interacts_with DrugCentral:3399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleandrin targets Unclassified (Neurogenic locus notch homolog protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:996ea286-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:996ecb08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:996ef31c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:996f1c02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:996f442a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:996f6da6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:996f9592-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:996fbda6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01469 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, epidermal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:996fe646-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:99700eb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:997036be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07148 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:99705ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:997086fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9970af72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9970d786-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9970ff90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:3401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ornithine is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9971305a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9971305a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9971305a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:99716e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:9971969e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.815']} DrugCentral uuid:9971bed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:9971e748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.372']} DrugCentral uuid:99720f66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.723']} DrugCentral uuid:99723798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:99725fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:9972886a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.533']} DrugCentral uuid:9972b182-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:9972d9be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.169']} DrugCentral uuid:997302ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.943']} DrugCentral uuid:99732b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:99735376-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.449']} DrugCentral uuid:99737bc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:9973a470-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.676']} DrugCentral uuid:9973ccac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9973f4c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:99741d10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:99744268-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:99746aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.333']} DrugCentral uuid:997492b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:9974bae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:9974e4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.209']} DrugCentral uuid:99750f18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9975372c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.969']} DrugCentral uuid:99755f2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:99758826-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:3412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybenzone targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9975b044-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:3413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycinchophen targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9975d86c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9976008a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:9976292a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine is modulator of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:99765152-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.658']} DrugCentral uuid:9976797a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.307']} DrugCentral uuid:9976a288-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:9976cd12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9976f56c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:99771d9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:997751c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:997751c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:997751c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:997751c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9977a30e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9977a30e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9977a30e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9977e170-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3467 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picloxydine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:997809fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:3467 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picloxydine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:99783224-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:3474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adipic acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:99785a4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:997883be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9978adb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:9978d5c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9978fdda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04015 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:99792648-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:99794e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03118 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.98']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9979ab86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:997a7a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:997a7a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:997a7a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:997abc56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:997abc56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:997aefb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03120 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Human papillomavirus regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:997b184a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polyestradiol phosphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:997b3bea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:997b5fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.398']} DrugCentral uuid:997b87da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:997bb05c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:997bd8fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:997c011a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:997c29e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:997c528c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:997c7bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.69']} DrugCentral uuid:997ca3f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:997ccc8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:997cf4b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18762 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:997d1ce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:997d457a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:997d761c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:997d761c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:997d761c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:997db5be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:997ddde6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:997e0f50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:997e0f50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:997e0f50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:997e4d76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:3500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protoporphyrin targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:997e756c-dc5e-11ec-be2c-0242ac110005 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:3500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protoporphyrin targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:997e9e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:997ec68e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:997eeea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:997f16c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:997f3fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:3505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homonicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:997f67d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:3506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxal phosphate targets Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:997f8fec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:997fb828-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:997fe1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:99800af8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:99803334-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:99805b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9980844c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:9980ac92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9980d4b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9980fd96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:998126ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:99814eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:998176d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:99819f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9981c87a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9981f0c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:998218d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:99824106-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:99826992-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:998291ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9982b9d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9982e282-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:99830ad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:99833412-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:99835c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:998385ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9983adca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9983d660-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9984070c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9984070c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9984070c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:998445aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:99846daa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:998495b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:9984be2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9984e64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:99850e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9985365e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:99855f8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:9985878a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9985afb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9985d7bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:998600ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:998628c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:998650c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:998678d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9986a12e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9986c942-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9986f14c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9987194c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:99874494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:99876eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:998796b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9987beb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9987e822-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9988102c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9988384a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:998860b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:998888ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9988b0b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9988d8ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:998903d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:99892e1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9989563a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:99897e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:9989a6b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9989ced0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9989f6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:998a1eda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:998a473e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:998a6f52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:998a9748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:998abf66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:998ae928-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:998b1146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:998b3946-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:998b6164-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:998b89aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:998bb1be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:998bdad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:998c0362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:998c2bee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:998c5402-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:998c7c02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:998ca4de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:998cce64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P39900 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Macrophage metalloelastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:998cf678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:998d1e78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:998d4768-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:998d6f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:998d979a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:998dbf9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:998de7f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:998e0ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06737 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Glycogen phosphorylase, liver form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:998e37fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:998e5ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:998e890c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:998eb102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:998ed902-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:998f022e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:998f2aa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:998f52b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:998f7bb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:998fa3d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:998fcc68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:998ff56c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:99901d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:999045a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:99907028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:99909832-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9990c05a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9990e85a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:999110c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:999138e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:99916104-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:99918986-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9991b1ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9991d9b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:999201cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:99922c06-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:99925640-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:99927e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9992a640-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9992ce9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:9992f6d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:99931ef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:999346fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:99936f58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10584 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:99939744-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21588 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (5'-nucleotidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9993bf62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q965D6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (3-oxoacyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9993e866-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q965D7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-hydroxyacyl-ACP dehydratase; Fatty acid synthesis protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:99941354-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27986 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Phosphatidylinositol 3-kinase regulatory subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:99943c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPH5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (NADPH oxidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:99946494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:99948ca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9994b516-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9994dd34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q1CTD3 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (D-alanine--D-alanine ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:99950674-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:99952eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:99955af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:99955af2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9995921a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:9995921a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:9995d1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9995d1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9995d1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9995d1d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:99961f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:99961f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:999655f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:999655f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:999689ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9996b1e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:9996d9ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:999701f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:99972b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03114 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cell division protein kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:99975366-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:99977b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07862 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (D-alanylalanine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9997a4d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:9997cdd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01062 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9997f5dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:99981dfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41921 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:999846ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:99986f08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:99989712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11168 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9998bf08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14576 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (ELAV-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9998e794-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15717 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (ELAV-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99990fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:999937b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:99995fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19357 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:99998a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9999b41c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9999dc44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:999a046c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:999a3c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:999a3c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:999a3c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:999a3c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:999a3c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:999a87f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:999ab07e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:999ad9aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:999b01a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:999b29b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:999b534e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:999b7c52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:999ba470-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:999bcc8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:999bf51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:999c1d24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:999c459c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:999c6dba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:999c9632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:999cbe3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:999cea2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:999cea2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:999d179c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:3529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rioprostil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) DrugCentral uuid:999d3dc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:999d65bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.46']} DrugCentral uuid:999d8db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:999dc228-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:999dc228-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:999dc228-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:999dc228-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:999e0b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WQX9 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (Phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:999e3370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:999e5bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:999e8514-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:999ead32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:999ed564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:999efef4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:999f2a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:999f53f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:999f7d2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:999fa5f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:999fce1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:999ff642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:99a01e42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:99a046c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:99a06ece-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:99a096ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:99a0bed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:99a0ea2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:99a11446-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:99a13c78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:99a16504-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:99a18d36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:99a1b54a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:99a1dd7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:99a205fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:99a22e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:99a25720-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:99a27f48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99a2a860-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:99a2d092-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:99a2f892-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:99a320b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:99a3495a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:99a37204-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:99a39a18-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:99a3c236-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:99a3eaae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:99a412c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:99a43ad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99a462e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:99a48bf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:99a4b42a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:99a4dc34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:99a50452-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:99a52ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99a5561e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:99a57e32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99a5a650-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:99a5cee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:99a5f6fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:99a61f18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:99a648e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:99a6710c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:99a6992a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:99a6c13e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:99a6ea38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:99a71260-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99a73a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:99a76288-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:99a78af6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:99a7b31e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:99a7db32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:99a80382-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:99a82d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:99a8559e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:99a87db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:99a8a5c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:99a8ce70-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:99a8f670-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:99a91e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99a946a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:99a96f10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:99a9972e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99a9bf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:99a9e7f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:99aa1244-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:99aa3b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:99aa637a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:99aa8b8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:99aab49c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:99aadcba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:99ab04ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:99ab2e68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99ab56b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99ab7eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:99aba712-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:99abcfc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:99abf7ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:99ac2002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:99ac4802-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99ac70c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:99ac98c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:99acc0c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:99ace8d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:99ad1142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:99ad3960-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:99ad617e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:99ad899c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:99adb336-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:99addb68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:99ae0476-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:99ae2ca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:99ae555c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:99ae7d7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:99aea5b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:99aece38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99aef6ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:99af1ed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:99af46ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:99af6fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:99af9836-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:99afc054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41743 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C iota type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99afe85e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99b01130-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:99b03958-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99b061ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:99b089f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99b0b270-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b0f500-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:99b17b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:99b17b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:99b17b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:99b17b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:99b1c4c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b20f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:99b28a78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:99b2b296-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:99b2dadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.454']} DrugCentral uuid:99b3030e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:99b32c30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:99b35444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:99b37c4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:99b3a458-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:99b3ccf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:99b3f4f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:99b41cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:99b4452a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:99b46e9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:99b496b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:99b4beb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:99b4e7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:99b5111c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:99b53944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:99b56180-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:99b58a48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:99b5b270-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:99b5e9b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:99b5e9b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:99b5e9b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:99b5e9b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:99b5e9b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:99b63ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:99b666e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:99b68f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:99b6b76a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin is antagonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:99b6e4c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:99b6e4c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:99b7189a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:99b740d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:99b76994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:99b791c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:99b7b9d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:99b7e6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:99b7e6d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:99b81a88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbentine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:99b842a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:3557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbentine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:99b86ace-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:99b89788-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:99b89788-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:99b8cd98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxedrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:99b8f5c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxedrine targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:99b91dd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:99b94232-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:99b96a5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:99b9926e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:99b9ba64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:99b9e2e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:99ba0ae6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:99ba3462-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:99ba5c94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:99ba8656-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:99baae9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:99bad6c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:99bafeec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:99bb23e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:99bb4bea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:99bb73fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:99bb9c26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:99bbc598-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:99bbedde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:99bc161a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:99bc475c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:99bc475c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:99bc475c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:99bc8dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99bc8dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99bc8dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99bcdff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99bcdff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99bcdff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99bcdff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99bcdff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99bcdff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99bd52fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:99bd52fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:99bd52fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:99bd52fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:99bd52fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:99bd52fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:99bda7a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:99bdcfa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:99bdf7d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:99be2158-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:99be49f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:99be7234-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:99be9c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:99bec50e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:99beed5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99bf15a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:99bf3db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:99bf663a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.72']} DrugCentral uuid:99bf8e62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:99bfb680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:99bfde8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:99c008b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:99c030a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:99c05464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:99c07c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:99c0a52c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:99c0cd36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:99c0f54a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Pepsin A-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99c11d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:99c145d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:99c16df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:99c19608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:99c1bed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:99c1e928-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:99c211d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:99c239d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:3613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Vitamin E targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:99c262a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49638 biolink:molecularly_interacts_with DrugCentral:3613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Vitamin E targets Transporter (Alpha-tocopherol transfer protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:99c28b9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:99c2b3c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:99c2dbee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:99c30466-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.75']} DrugCentral uuid:99c32c8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:99c354c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:99c37cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:99c3a6c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:99c3cefa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:99c3f718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:99c426de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:99c426de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:99c426de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:99c46e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99c46e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99c46e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99c4acda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:99c4d548-dc5e-11ec-be2c-0242ac110005 UniProtKB:P95276 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase; Epoxide hydrolase EphB) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:99c4fd5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07099 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:99c52552-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D379 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:99c54d7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:99c57674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16152 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Carbonyl reductase [NADPH] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:99c59e92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6GI75 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:99c5c6c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:99c5eeba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:99c61868-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54616 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:99c64090-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6UCJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-acyl carrier reductase; Enoyl-acyl carrier reductase ENR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:99c668c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BJJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-ACP reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:99c690f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9RMI3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:99c6b980-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:99c6e19e-dc5e-11ec-be2c-0242ac110005 UniProtKB:M9TGV3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NULLDH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:99c709ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:99c73202-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:99c75c0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:99c78432-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:99c7acc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:99c7d4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:99c7fd9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:99c825c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:99c84db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:99c87630-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:99c89e58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:99c8c680-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1BI31 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:99c8ee94-dc5e-11ec-be2c-0242ac110005 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:99c91824-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:99c94218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:99c96a40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:99c99286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99c9bba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca0298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:99ca7610-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:99ca9e10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:99cac642-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:99caefc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:99cb1868-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:99cb409a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:99cb68cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:99cb918a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:99cbb994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99cbe1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:99cc09bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:99cc323e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:99cc5a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:99cc82b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:99ccaae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:99ccd59a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:99ccffb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:99cd27f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:99cd502e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:99cd79e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:99cda204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:99cdca04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:99ce0258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:99ce0258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:99ce0258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:99ce0258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:99ce0258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:99ce56b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:99ce7ee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:99ceac80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:99ced4bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:99cefcd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:99cf2d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:99cf2d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:99cf2d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:99cf72f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:99cf72f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:99cf72f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:99cfc3fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99cfc3fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99cfc3fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99cfc3fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99cfc3fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99cfc3fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:99d024ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:99d04cfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.163']} DrugCentral uuid:99d07678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:99d09edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:99d0c70e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:99d0ef54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:99d117e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:99d1401c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99d16862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:99d19094-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:99d1b934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:99d1e17a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:99d209c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:99d231d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:99d25c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:99d284a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:99d2acd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:99d2d544-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:99d2fd80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:99d325bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:99d34de4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:99d376c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:99d39ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:99d3c80a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:99d3f03c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:99d41a44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:99d44244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:99d46a6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:99d492b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:99d4bbd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:99d4e410-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:99d50c38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:99d5346a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:99d55d3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:99d58d0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:99d58d0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:99d58d0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:99d5da8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99d5da8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99d5da8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99d5da8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99d5da8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99d63e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:99d63e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:99d63e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:99d68716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:99d68716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:99d68716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:99d6c55a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:99d6ed82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:99d7169a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:99d73f9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:99d767c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:99d79796-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:99d79796-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:99d79796-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:99d7d814-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:99d80032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:99d8288c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:99d850be-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:99d87a8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bropirimine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:99d8a2a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:3707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorthenoxazine targets Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:99d8cada-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciramadol is modulator of GPCR (Mu-type opioid receptor) DrugCentral uuid:99d8eea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:3715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobenztropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:99d91f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:99d91f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:99d91f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:99d96512-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:99d96512-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:99d96512-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:99d9a4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 myrtecaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:99d9d498-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:99d9d498-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:99d9d498-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:99da17d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:99da17d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:99da4b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:99da742a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:99da9c3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:99dac4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:99daecfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:99db1510-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:99db3d42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:99db6678-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:99db91f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:99dbbc2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:99dbe44a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:99dc0ccc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:99dc34d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:99dc5cea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:99dc8526-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:99dcadf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:99dcd620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:99dcfe48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:99dd2652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:99dd5000-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:99dd7814-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:99dda168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:99ddca62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:99ddf2f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:99de1b20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:99de4352-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:99de6b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:99de942e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:99debc4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:99dee438-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22736 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Nuclear receptor subfamily 4 group A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:99df0d32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:99df355a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99df5da0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 artemisinin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:99df865e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:99dfaed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:99dfd6d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:99dffefe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:99e026fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:99e04fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.843']} DrugCentral uuid:99e07bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:99e07bd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:99e0ba6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:99e0ba6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:99e0ba6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:99e0ba6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:99e10466-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:99e12c70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:99e15574-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:99e17e1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:99e1a66e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:99e1ca40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:99e1f27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:99e21b44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.665']} DrugCentral uuid:99e24376-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.372']} DrugCentral uuid:99e26bbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:99e293ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:99e2bcb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:99e2e4fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:99e30d1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:99e33682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:99e35f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:99e3874a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:99e3af7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:99e3d7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:99e40058-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:99e4379e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:99e4379e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:99e4379e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:99e4379e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:99e4379e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:99e49522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:99e49522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:99e49522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:99e4e0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:99e4e0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:99e4e0d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:99e51f38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:99e547c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:99e56fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:99e598aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99e5c154-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:99e5e9a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.79']} DrugCentral uuid:99e611e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:99e63a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:99e664c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:99e68d1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:99e6b532-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:99e6dd46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:99e705a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:99e72db4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:99e755b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:99e77ddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:99e7a6ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.57']} DrugCentral uuid:99e7cee0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:99e7f712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:99e8203e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:99e84ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:99e875de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:99e89df2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:99e8c610-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolasetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.226']} DrugCentral uuid:99e8ef00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.698']} DrugCentral uuid:99e91746-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:3944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide phosphate is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:99e93b22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:99e9635e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:99e98be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:99e9b41c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:99e9dc44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:99ea0494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:99ea2e9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.793']} DrugCentral uuid:99ea56c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:99ea7ef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:99eaa7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:99eacff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:99eaf8b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:99eb20cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.122']} DrugCentral uuid:99eb4944-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:99eb7162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:99eba114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:99eba114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:99eba114-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:99ebe052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:99ec0820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:99ec0820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:99ec36a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:99ec5ee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:99ec87be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:99ecafe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:99ecd7fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:99ed0040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.924']} DrugCentral uuid:99ed28b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.891']} DrugCentral uuid:99ed50f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:99ed791c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:99eda180-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.451']} DrugCentral uuid:99edcc82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.539']} DrugCentral uuid:99edf4be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is allosteric modulator of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:99ee1cc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:99ee5102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99ee5102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99ee5102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99ee5102-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:99ee9a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P91730 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:99eebe3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:99eee1f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11507 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:99ef0a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06685 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:99ef3284-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64578 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:99ef5aac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is allosteric modulator of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:99ef82ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:3976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kinetin targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:99efad86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:99efd680-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:99effebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:99f027fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00371 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:99f05042-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:99f0786a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:99f0a074-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2ZB02 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:99f0c9dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:99f0f27c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00024 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:99f11ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meldonium targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:99f142d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:99f16c02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:99f1943e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niperotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:99f1b806-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:99f1e01a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:99f208d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:99f230f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:99f2590a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:99f2851a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:99f2851a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:99f2b8d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:99f2e104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:99f30922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:99f3335c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:99f35d82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:99f38596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:99f3add2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:4050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spaglumic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:99f3d762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:99f3ff8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:99f4279e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f48900-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:99f55c18-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:99f5845e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:99f5ad26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:99f5d54e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:99f5fd80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:99f625b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:99f64f2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.78']} DrugCentral uuid:99f6777e-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.44']} DrugCentral uuid:99f69fb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:99f6c7ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:99f6f316-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.929']} DrugCentral uuid:99f71d46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.425']} DrugCentral uuid:99f74582-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.857']} DrugCentral uuid:99f76dbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:99f7967c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:99f7bfd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.802']} DrugCentral uuid:99f7e802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.952']} DrugCentral uuid:99f8107a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:99f838ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:99f860de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:99f888f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13674 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Prolyl 4-hydroxylase subunit alpha-1) DrugCentral uuid:99f8ad5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02809 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1) DrugCentral uuid:99f8d302-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGH3 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 2) DrugCentral uuid:99f8f6c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHI7 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 1) DrugCentral uuid:99f91a74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00689 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:99f942a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:99f96b6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:99f993a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:99f9bbd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:99f9e85a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:99f9e85a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:99fa15fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:4106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sucralfate is inhibitor of Enzyme (Pepsin A-5) DrugCentral uuid:99fa39e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:99fa632a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:99fa8c92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:99fab690-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:99fadea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:99fb06b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:99fb2f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:99fb579e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:99fb7fb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:99fba7d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:99fbd052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:99fbf87a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:99fc248a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:99fc248a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:99fc5c8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:99fc5c8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:99fc8fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:99fcb7ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:99fce014-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:99fd08d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:99fd319a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:99fd5eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:99fd5eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:99fd90c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:99fd90c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:99fdbe3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:99fde658-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:99fe0f66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:99fe384c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:99fe6074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:99fe88a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:99feb0d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) DrugCentral uuid:99fed568-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:99fef958-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) DrugCentral uuid:99ff1d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) DrugCentral uuid:99ff411a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasugrel is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:99ff6532-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:99ff88fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:99ffacfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:99ffd51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:99fffd4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9a002706-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9a004f2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9a00774c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9a00a032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:9a00c850-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.187']} DrugCentral uuid:9a00f078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:9a0118b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.61']} DrugCentral uuid:9a014140-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9a016972-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.93']} DrugCentral uuid:9a0191ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9a01b9d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:9a01e2d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9a020be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.73']} DrugCentral uuid:9a02341a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9a025c24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.644']} DrugCentral uuid:9a0284e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9a02acf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:9a02d618-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.107']} DrugCentral uuid:9a02fe4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.039']} DrugCentral uuid:9a0326d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.491']} DrugCentral uuid:9a034eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.565']} DrugCentral uuid:9a03771c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9a039f58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9a03c94c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:9a03f17e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:9a0419b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:9a0441c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:9a046b22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:9a04934a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9a04bb86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9a04e41c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:9a050c8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9a0534b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:9a055cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a058674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9a05b09a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9a05d8cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9a0601e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9a062aca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9a06531a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9a067b42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a06a360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9a06cbd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a06f400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9a071c1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9a07443c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:9a076e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9a07966c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9a07be9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9a07e6da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9a08101a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9a08386a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9a08607e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a0888a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a08b150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9a08daae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9a0902ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a092c3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9a095484-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9a097ca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a09a4ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a09cfd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9a09f916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a0a213e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9a0a49de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:9a0a72d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9a0a9b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a0ac33c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9a0aeb50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a0b14e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9a0b3cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9a0b6512-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a0b8d30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9a0bb5bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9a0bdde4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a0c05f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9a0c2e02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a0c5684-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9a0c7e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a0ca6ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9a0cceb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9a0cf99a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9a0d21cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9a0d49ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9a0d724e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9a0d9a76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a0dc280-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9a0deba2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9a0e13fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9a0e3c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9a0e6442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9a0e8c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) DrugCentral uuid:9a0eb208-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9a0edd8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:9a0f05aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9a0f2dc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9a0f564a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9a0f7e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9a0fa69a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9a0fcec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9a0ff730-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9a101f4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9a10474e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9a106f9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9a1099e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9a10c20a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a10ea1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9a1112dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a113b5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9a116390-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9a118bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a11b43a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a11dd66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a12058e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9a122dac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a125714-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:9a127f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9a12a75a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a12cf6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9a12f7e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a131fe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9a1347fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9a13700e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9a1398a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9a13c0a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a13e8f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9a141108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9a143ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9a1462fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9a148b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9a14b32e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:9a14dcdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9a15050e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9a152d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9a155568-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a157dfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a15a6ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a15cf34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9a15f748-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:9a1620d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9a1648f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9a16713c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.328']} DrugCentral uuid:9a1699be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9a16c1e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.604']} DrugCentral uuid:9a16ea04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:9a171236-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9a173ad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:9a176312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:9a178b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a17b376-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9a17e134-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9a17e134-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9a181834-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:9a181834-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:9a184b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z2V5 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a1899da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a19325a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9a195a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9a198278-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9a19ad52-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9a19d57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9a19fd66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a1a2584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9a1a4dfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a1a762e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:9a1a9e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:9a1ac660-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9a1aeec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.405']} DrugCentral uuid:9a1b16e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:9a1b3ab4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:9a1b5e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.922']} DrugCentral uuid:9a1b882a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9a1bb052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51788 biolink:molecularly_interacts_with DrugCentral:4123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubiprostone is opener of Ion channel (Chloride channel protein 2) DrugCentral uuid:9a1bd424-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9a1bfc6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9a1c25aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9a1c4e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9a1c774e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9a1c9f9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9a1cc870-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:9a1cf098-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9a1d18b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9a1d40fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9a1d6a8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9a1d92c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q94F81 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (HD2 type histone deacetylase HDA106; Histone deacetylase 2b; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9a1dbadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O09106 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:9a1de304-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ZTP8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9a1e0b7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:9a1e341c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q70I53 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase-like amidohydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9a1e5c3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9a1e84b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7K6A1 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9a1eace4-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:9a1ed50c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f0108-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9a1f0108-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9a1f39d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9a1f39d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a1f9442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a2037bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a2037bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a2037bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a2037bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a2085a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a2085a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9a20cf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a20cf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a20cf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a20cf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a20cf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a20cf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a20cf4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:9a213ed2-dc5e-11ec-be2c-0242ac110005 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9a216718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24527 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9a218f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:4125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9a21b7ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:4125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proline targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:9a21e012-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asparagine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9a220844-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9a2230bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9a225bfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07314 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9a22845e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63116 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Unclassified (Asc-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9a22ac7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9a22d670-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:4128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:9a23006e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:4134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxal targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9a2328aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:9a234dda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:9a237224-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:9a239600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9a23be28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:9a23e650-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:9a240f40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.925']} DrugCentral uuid:9a243786-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a245f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9a2487b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:9a24b300-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.209']} DrugCentral uuid:9a24db3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:9a250350-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:9a252b82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:9a25540e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:9a257c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.635']} DrugCentral uuid:9a25a47c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:9a25ccc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:9a25f698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.251']} DrugCentral uuid:9a261eca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.916']} DrugCentral uuid:9a2646f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:9a26701e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:9a269b48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:9a26c38e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:9a26ebc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.265']} DrugCentral uuid:9a2714ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:9a273ce2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.556']} DrugCentral uuid:9a276528-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:9a278d50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9a27b5e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:9a27de18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9a28065e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9a282ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:9a285866-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.975']} DrugCentral uuid:9a28808e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:9a28a8ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:9a28d106-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9a28f988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.124']} DrugCentral uuid:9a2922fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:9a294b36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9a297372-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.945']} DrugCentral uuid:9a299c8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:9a29c4a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:9a29ecd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:9a2a150c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:9a2a3eba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.416']} DrugCentral uuid:9a2a67d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:9a2a900e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9a2ab84a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.084']} DrugCentral uuid:9a2ae0c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:9a2b0962-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.012']} DrugCentral uuid:9a2b3194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9a2b5a98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.233']} DrugCentral uuid:9a2b82d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.325']} DrugCentral uuid:9a2baafc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:9a2bd338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:9a2bfcd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9a2c2518-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:9a2c4d36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 udenafil targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9a2c7130-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 udenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.084']} DrugCentral uuid:9a2c99b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine silver is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:9a2cbdac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine silver targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9a2ce5de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9a2d0e06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.658']} DrugCentral uuid:9a2d369c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.85']} DrugCentral uuid:9a2d5ef6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.21']} DrugCentral uuid:9a2d871e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.96']} DrugCentral uuid:9a2daf50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9a2dd890-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:9a2e00cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9a2e2908-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9a2e5144-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:9a2e7b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:9a2ea338-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a2ee230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a2ee230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a2ee230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a2ee230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a2ee230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a2ee230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a2ee230-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a2f4202-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9a2f6a20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9a2f923e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:9a2fbbd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9a2fe3ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:9a300c14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9a3034be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9a305da4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a3085ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant is antagonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:9a30ae26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9a30d69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9a30fab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:9a3122f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9a314b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9a317464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9a319f84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2VKV7 biolink:molecularly_interacts_with DrugCentral:4152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 permethrin is blocker of Ion channel (Sodium channel protein) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a31e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9a325636-dc5e-11ec-be2c-0242ac110005 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:4156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edaravone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:9a328246-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9a328246-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:9a32b02c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9a32d412-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) DrugCentral uuid:9a32f7da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9a331fee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) DrugCentral uuid:9a3349e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:9a3349e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:9a337980-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9a33a1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a345e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a3644f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9a366d84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9a3695b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liraglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.2']} DrugCentral uuid:9a36bdca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcaftadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:9a36e1a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ulipristal is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9a370d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95470 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod targets Enzyme (Sphingosine-1-phosphate lyase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9a37375a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9a375f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9a378782-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9a37b02c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9a37d84a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923J1 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9a38005e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:9a3828f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:9a38511c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.305']} DrugCentral uuid:9a387930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.967']} DrugCentral uuid:9a38a130-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:9a38caac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:9a38f608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:9a391e62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.003']} DrugCentral uuid:9a394798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:9a398758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a398758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a398758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a398758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a398758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a398758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a398758-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9a39e50e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:4170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tesamorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3a27c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a3aaab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9a3ad2ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9a3afae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9a3b22de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9a3b4b92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9a3b739c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9a3b9b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9a3bc37e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9a3bebec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBX1 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a3c1900-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9a3c1900-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9a3c4c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9a3c7580-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9a3c9e7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9a3cc68e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNI1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Chymotrypsin-like elastase family member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9a3cee84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a3d171a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9a3d3f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9a3d672e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9a3d8f38-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:9a3db77e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9a3de000-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9a3e0bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:9a3e0bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:9a3e3960-dc5e-11ec-be2c-0242ac110005 UniProtKB:C1KIQ2 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9a3e6390-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9a3e8bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q91RS4 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:9a3eb3ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9a3edbf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:9a3f005c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9a3f285c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9a3f5192-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9a3f79ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9a3fa1f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:9a3fca14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9a3ff2fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9a401c44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9a404660-dc5e-11ec-be2c-0242ac110005 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9a406e88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a409692-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9a40bf46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:9a40e750-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:9a410f78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:9a413778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9a416018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:4177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) DrugCentral uuid:9a4183f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:4177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) DrugCentral uuid:9a41a7c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9a41cfb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9a41f96a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9a4223a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:9a424bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:9a4273cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9a429c6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9a42c458-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9a42ec62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a431476-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a433d16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9a4365b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9a438dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9a43b5e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9a43e216-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9a440c00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a443414-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9a445cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9a4484c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9a44acc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9a44d4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a44fd5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:9a4526a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9a454ec6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9a457716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a45a09c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:9a45c996-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9a45f196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a4619a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9a4642e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9a466aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a4692fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9a46bb08-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9a46e362-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a470b8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:9a4733b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9a475bd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a4785b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a47add8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9a47d704-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9a47ff18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a4827cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9a484fe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a4877f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a48a026-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9a48c8a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9a48f0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9a4918d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9a4941e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.34']} DrugCentral uuid:9a496af6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9a499314-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9a49bb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9a49e44a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9a4a0c4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9a4a3472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9a4a5c72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9a4a84ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9a4aacea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a4ad4fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a4afe34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9a4b274c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9a4b4f6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9a4b777e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9a4b9f9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9a4bc95e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9a4bf168-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a4c1990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9a4c41c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9a4c6a3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a4c9244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9a4cba62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a4ce276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9a4d0c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9a4d3442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9a4d5c74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9a4d8532-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9a4dad6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a4dd55a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9a4dfd78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9a4e25dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a4e4e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:9a4e7604-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9a4e9e22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9a4ec79e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9a4ef1ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9a4f19f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a4f420a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9a4f6ac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a4f930e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a4fbc08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9a4fe444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9a500ca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:9a5034da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a505ce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9a508584-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9a50ae4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a50d656-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9a50ff82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9a5127b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9a515068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9a517886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a51a090-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9a51c8d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:9a51f0f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9a521908-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:9a524112-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9a5269e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9a5291ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9a52ba16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9a52e248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9a531682-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:9a531682-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:9a531682-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:9a531682-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:9a53576e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9a538072-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9a53a8ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9a53d112-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9a53f91c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z351 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a542126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9a544a3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9a54725c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9a549a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:9a54c2c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9a54eb4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9a55134c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:9a553b6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9a556392-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor is negative allosteric modulator of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9a558c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9a55b478-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EPX4 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor targets GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9a55dc6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9a560482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9a562ed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a5656ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:9a56802e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9a56a8ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:9a56d128-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22830 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Enzyme (Ferrochelatase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9a56f950-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9a572164-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:9a574a90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25023 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.11']} DrugCentral uuid:9a5776fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70526 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.96']} DrugCentral uuid:9a579f18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46663 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9a57c754-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32299 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:9a57f0ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97583 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9a581b14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9a58433c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:9a586b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9a5893be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9a58bbd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a58e404-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9a590c18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9a5934e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9a595d4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a59856c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9a59ad76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a59d80a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a5a0014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9a5a2832-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a5a5032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9a5a78b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9a5aa0dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a5ac8fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9a5af17c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9a5b19b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9a5b41ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9a5b6b02-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9a5b944c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a5bbf94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9a5be7d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9a5c0fda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9a5c39e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9a5c6214-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9a5c8b4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9a5cb37c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9a5cdbea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9a5d041c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9a5d2cda-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:9a5d54f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9a5d7eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9a5da6ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9a5dcec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9a5df6e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a5e2018-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a5e484a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9a5e704a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9a5e9886-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9a5ec144-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.13']} DrugCentral uuid:9a5ee976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9a5f119e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:9a5f3ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9a5f6428-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9a5f8c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9a5fb45a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9a5fdd7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9a600586-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9a602d9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9a6055ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9a607e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a60a64e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9a60ce6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9a60f68a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9a6120ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9a6149e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9a6171f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a6199fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9a61c290-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9a61ea9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9a6212b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9a623ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9a626452-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9a628c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a62b4ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9a62dcc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a63079a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9a632fa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9a6358bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a638134-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9a63a966-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9a63d1de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9a63fa1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a642288-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9a644ab0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9a6472ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9a649ae2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9a64c4fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a64ed9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9a65159e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9a653da8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9a656670-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9a658e98-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9a65b68e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9a65de98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a660d6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a663596-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9a665d8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9a6685b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9a66b048-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9a66d866-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9a67008e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9a6728fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a675228-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:9a677a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9a67a25a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9a67cb0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9a67f322-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9a681b40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9a684354-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9a686dac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a6895d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9a68bde8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a68e5f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9a690e6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9a693674-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9a695e88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a6986a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a69af5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9a69d782-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:9a69ff96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:9a6a27b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9a6a5248-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9a6a7a7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9a6aa324-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9a6acb56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a6af43c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9a6b1c5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9a6b4568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9a6b6dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9a6b9608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9a6bbe1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9a6be644-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9a6c0fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a6c396e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9a6c6182-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9a6c8996-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a6cb236-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a6cda54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9a6d0268-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a6d2a72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a6d52fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9a6d7b08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:9a6da326-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9a6dcb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a6df47a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9a6e1cb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9a6e45e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a6e6df6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9a6e96d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62190 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9a6ebed2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02858 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9a6ee6dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a6f0ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9a6f3880-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9a6f609e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9a6f88a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9a6fb5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:9a6fb5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:9a6fed2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15357 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Enzyme (Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9a701570-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9a703d98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NB16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mixed lineage kinase domain-like protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9a706660-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9a708e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:4188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferiprone targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9a70b714-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:9a70df32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.261']} DrugCentral uuid:9a7107b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.573']} DrugCentral uuid:9a712fd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9a71580e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9a718040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.501']} DrugCentral uuid:9a71ab9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:9a71d59a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:9a71fdd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.664']} DrugCentral uuid:9a722676-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9a724e94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a72769e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9a729ea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a72c7f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9a72effc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a731810-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a734038-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9a736964-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9a73918c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9a73b996-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9a73e22c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9a740be4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:9a74340c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9a745c34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9a74845c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a74ad24-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.44']} DrugCentral uuid:9a74d542-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9a74fd74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9a75259c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9a7550ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9a757b1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9a75a328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9a75cb8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9a75f3be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9a761c04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9a76440e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9a766ce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9a769602-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9a76be98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9a76e6a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9a771028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:9a77383c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9a776050-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a778846-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9a77b0be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a77d8dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9a78010e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9a78290e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9a7851e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9a7879fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9a78a230-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9a78ca30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9a78f32a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a791b3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9a79435c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a796b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9a7993d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9a79bbe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a79e4a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9a7a0df0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9a7a3672-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9a7a5e9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9a7a87bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9a7ab0ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9a7adabe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9a7b02c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9a7b2ad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a7b5372-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a7b7ba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9a7ba3d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a7bcbf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9a7bf46c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9a7c1c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a7c449e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a7c6cbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9a7c96d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9a7cc14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9a7ce96c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9a7d1180-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a7d3a34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9a7d62b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a7d8ab6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9a7db2d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:9a7ddb60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9a7e037e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a7e2b88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9a7e53b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9a7e7fa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9a7ea7ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9a7ecfc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a7ef838-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a7f206a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9a7f4888-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9a7f70a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9a7f9928-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9a7fc13c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9a7fea7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9a80129a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9a803cca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9a806704-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a808f22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a80b72c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9a80df90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:9a8107b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9a812fe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9a8157e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a818080-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a81a89e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a81d0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9a81f8e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9a822486-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a824d80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9a8275d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9a829e3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9a82c648-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9a82ee52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9a83167a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a833ee8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a836710-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a838f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9a83b742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9a83e186-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9a840b8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9a8433ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a845bc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a84842e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a84ac38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a84d42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a84fc4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9a852492-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9a854cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9a8574c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:9a859cd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9a85cb18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9a85cb18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9a86039e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:9a86039e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:9a863bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:9a863bf2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:9a867716-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9a867716-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9a867716-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9a86b938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9a86b938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9a86ecb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9a8714f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9a873d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:9a876536-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9a878f52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.393']} DrugCentral uuid:9a87b96e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:9a87e1a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:9a8809a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:9a883204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:9a885a2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:9a888254-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:9a88aa72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.627']} DrugCentral uuid:9a88d2fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is binding agent of Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.812']} DrugCentral uuid:9a88fb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99707 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase) DrugCentral uuid:9a891ef8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBK8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase reductase) DrugCentral uuid:9a8942ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXJ7 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Unclassified (Protein amnionless) DrugCentral uuid:9a8967aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96EY8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial) DrugCentral uuid:9a898b86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH4 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methylmalonic aciduria type A protein, mitochondrial) DrugCentral uuid:9a89b0ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20062 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-2) DrugCentral uuid:9a89d47e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20061 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-1) DrugCentral uuid:9a89f8b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:4197 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vitamin A palmitate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9a8a20d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:4197 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vitamin A palmitate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9a8a490e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4199 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium chloride targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9a8a7136-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:9a8a99a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:9a8ac5c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:9a8ac5c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:9a8af48a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:9a8b1852-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a8b423c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a8b6a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:9a8b9296-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.582']} DrugCentral uuid:9a8bbadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:9a8be35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9a8c0b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:9a8c33c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9a8c5bea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:9a8c8462-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9a8cac9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9a8cd50c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:9a8cfe10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9a8d2872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.157']} DrugCentral uuid:9a8d5090-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.394']} DrugCentral uuid:9a8d78b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9a8da216-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:9a8dca34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9a8df266-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9a8e1aa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9a8e42fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9a8e6b10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:9a8e932e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a8ebb60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:9a8ee496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:9a8f0cc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9a8f357c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9a8f5dae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:9a8f866c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:9a8fae8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9a8fd69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:9a90063c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9a90063c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9a90063c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9a904ca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:9a904ca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:9a904ca0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:9a9093fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9a9093fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9a9093fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9a90ddf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:9a90ddf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:9a90ddf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:9a91251c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9a91251c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9a91251c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9a916432-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:9a918c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9a91b464-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9a91dc96-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15552 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid is agonist of GPCR (Free fatty acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9a920522-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14843 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9a922d4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9a925108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9a928218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:9a928218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:9a928218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:9a92bcf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium phosphate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9a92e532-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:4220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telbivudine targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9a930d64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:4220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telbivudine is inhibitor of Polyprotein (Protein P) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:9a93360e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4221 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequinol is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:9a9359c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9a9381ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9a93aa12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9a93d29e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9a93fac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9a9422da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9a944b02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9a947474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9a949d78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9a94c578-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9a94ee18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9a9516ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a953eae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9a9566ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:9a95905c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a95b85c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9a95e066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9a960870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9a963156-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9a965956-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9a96853e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9a96853e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9a96c012-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9a96c012-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9a96c012-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9a970694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a970694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a970694-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9a9744e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9a976d64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9a979582-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9a97bdb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9a97e604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.31']} DrugCentral uuid:9a981066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9a983884-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a9860ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a9888c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9a98b188-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9a98d9ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:9a990200-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:9a992a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9a9952be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9a997adc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.29']} DrugCentral uuid:9a99a2f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9a99cb0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9a99f67e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a9a2068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a9a4854-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9a9a7126-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a9a9930-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9a9ac14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9a9aea7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a9b12e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9a9b3b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9a9b634c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a9b8b74-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:9a9bb45a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9a9bdcf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9a9c05e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9a9c2dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9a9c5662-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9a9c7e76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9a9ca68a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9a9cce9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9a9cf752-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a9d1f66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9a9d478e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9a9d6fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a9d9888-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:9a9dc0a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9a9de8ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9a9e10ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9a9e393c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9a9e6164-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9a9e898c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9a9eb286-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9a9edaae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a9f02d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9a9f2ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9a9f5420-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9a9f7edc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9a9fa6f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9a9fcf0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9a9ff862-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9aa02080-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9aa048b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9aa070bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9aa09970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9aa0c17a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9aa0eb14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9aa11328-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9aa13e02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9aa16684-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9aa18eb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9aa1b6b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9aa1df42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9aa2077e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9aa22f92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9aa25792-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9aa2805a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9aa2a8e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9aa2d0f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9aa2f9fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9aa3250a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9aa35034-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9aa37a50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9aa3a2d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9aa3cae6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:9aa3f408-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9aa41c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9aa4448a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9aa46c9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9aa494bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9aa4bcee-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9aa4e6b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9aa50ed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9aa536f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9aa55f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9aa587dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9aa5affa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:9aa5d804-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9aa60022-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9aa6289a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9aa650a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9aa678ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9aa6a162-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9aa6c96c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9aa6f2ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9aa71afc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.79']} DrugCentral uuid:9aa743ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:9aa76c00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.197']} DrugCentral uuid:9aa79414-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9aa7bc1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:9aa7e590-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.328']} DrugCentral uuid:9aa80d86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9aa8359a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15465 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9aa85dd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib is inhibitor of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:9aa88734-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9aa8afe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivacaftor is positive modulator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9aa8d810-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafluprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:9aa8fbe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginesatide is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.43']} DrugCentral uuid:9aa9248c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:9aa94854-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9aa97068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9aa9989a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:9aa9c108-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:9aa9e91c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:9aaa1144-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9aaa3976-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9aaa6306-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:9aaa8b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9aaab360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9aaadb6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9aab0428-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:9aab2c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9aab5478-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9aab7c82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:9aaba504-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9aabce1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9aabf644-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9aac1f20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9aac4d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:9aac4d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:9aac7b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9aaca440-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9aaccd12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4QYD9 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Unclassified (Heat sensitive channel TRPV3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9aacf530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9aad1d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9aad459e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:4264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamide targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:9aad6e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:9aad9602-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9aadbe16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9aade620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9aae1082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9aae3896-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9aae6096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9aae88b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:9aaeb172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9aaed990-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:9aaf01b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00720 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Endolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9aaf29ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:9aaf5262-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:9aaf7ad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9aafa2f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:9aafcd14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:9aaff762-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:9ab01f76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9ab04780-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9ab07002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9ab09866-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab140b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:9ab2b196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:9ab2da54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:9ab30290-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9ab32ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9ab352c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Florbetapir F-18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:9ab37c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:9ab3a74a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9ab3cf90-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9ab3f7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9ab42044-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9ab44858-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9ab47080-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6RI86 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9ab49916-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9ab4c2c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium iodide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9ab4eaec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9ab5131e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9ab53b64-dc5e-11ec-be2c-0242ac110005 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:9ab572f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:9ab572f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:9ab572f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:9ab572f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:9ab5c336-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9ab5ebfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:9ab61444-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9ab63c4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:9ab6644e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Flutemetamol (18F) targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9ab68ce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.69']} DrugCentral uuid:9ab6b53e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:9ab6dd7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:9ab705d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9ab72f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab77960-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:9ab7f4b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9ab81cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:9ab8450c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9ab86d84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9ab8967e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.87']} DrugCentral uuid:9ab8bed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:9ab8e700-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.201']} DrugCentral uuid:9ab9114e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9ab93d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:9ab93d2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:9ab971c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9ab99a88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9ab9c346-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9ab9eb50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9aba1382-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9aba3bf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9aba6422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:9aba8c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9abab47c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9abade34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9abb0648-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9abb2e7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9abb5698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9abb7f6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9abba7b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9abbcf9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9abbf7c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9abc2082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9abc488c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16555 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Dihydropyrimidinase-related protein 2) DrugCentral uuid:9abc6d4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9abc9576-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9abcbe5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9abce670-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9abd0e8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9abd3738-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9abd5f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9abd967e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9abd967e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9abd967e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9abd967e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9abd967e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9abdeb92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9abe1388-dc5e-11ec-be2c-0242ac110005 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9abe3b74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9abe6388-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9abe8eda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:9abeb914-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9abee132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9abf09be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9abf3218-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9abf5a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9abf8240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9abfaad6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9abfd308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9abffc02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9ac024ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ac04e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9ac077c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9ac09fc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9ac0c7c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ac0f080-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ac1189e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9ac140b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9ac168d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9ac19134-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9ac1b95c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9ac1e166-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9ac2097a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9ac2333c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9ac25b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9ac2836e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9ac2aba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9ac2d454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9ac2fc7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9ac3249a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:9ac34ca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9ac3751c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9ac39d3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9ac3c544-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9ac3ef4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9ac4197c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9ac441a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ac469b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azilsartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:9ac49262-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:4322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azilsartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9ac4bbb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:9ac4e3d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:9ac50c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9ac53492-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9ac55cc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:9ac584ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:9ac5ad1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9ac5d6f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant is antagonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.52']} DrugCentral uuid:9ac5ff30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9ac6274e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9ac64f58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9ac67848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9ac6a070-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:9ac6c924-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9ac6f16a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac7ae02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:9ac94de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambrisentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:9ac97728-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambrisentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:9ac99f96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9ac9c7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zucapsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:9ac9effa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:9aca18ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:9aca40e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9aca68fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.726']} DrugCentral uuid:9aca9126-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.363']} DrugCentral uuid:9acab9c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.958']} DrugCentral uuid:9acae1e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43194 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets GPCR (G-protein coupled receptor 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:9acb09e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6QR73 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets GPCR (G protein-coupled receptor 39-1b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9acb31ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPD8 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Unclassified (Ubiquitin-conjugating enzyme E2 T) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9acb5d04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9acb9e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9acb9e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9acb9e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9acb9e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9acb9e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9acb9e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9acb9e0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:9acbfdc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:9acc25f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:9acc4e3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:9acc77a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:9acc9fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9accc7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bilastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:9accf006-dc5e-11ec-be2c-0242ac110005 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:4357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anidulafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:9acd190a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:4358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine glutamate targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9acd411e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9acd693c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9acd91d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9acdba90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.54']} DrugCentral uuid:9acde2ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9ace0ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9ace32ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:9ace5b58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.23']} DrugCentral uuid:9ace8362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9aceab6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9aced380-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9acefc3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9acf2448-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9acf4c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9acf747a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9acf9d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9acfc56a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9acfed7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ad01592-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9ad03e1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9ad0672c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9ad08f54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.47']} DrugCentral uuid:9ad0b754-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9ad0e1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9ad109d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9ad131d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9ad15a88-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9ad182b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9ad1abe6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9ad1d418-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9ad1fc86-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9ad224b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9ad24d26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9ad2754e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9ad29ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9ad2ca12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.38']} DrugCentral uuid:9ad2f348-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9ad31b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9ad34406-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9ad36c24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9ad39424-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9ad3bc56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9ad3e4ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9ad40d6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9ad43582-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9ad45e86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9ad4874e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9ad4af76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9ad4d794-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9ad4ffb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9ad52870-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9ad55084-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9ad578a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9ad5a11a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9ad5c938-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9ad5f156-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9ad6196a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:9ad642b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9ad66bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:9ad693fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9ad6bc26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9ad6e4d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9ad70cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9ad73520-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9ad75d34-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9ad786c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9ad7aed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9ad7d700-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9ad7ff0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9ad82868-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9ad85162-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9ad8799e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.33']} DrugCentral uuid:9ad8a1b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9ad8ca66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9ad8f284-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9ad91a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:9ad9428e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9ad96b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9ad9932e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9ad9bb6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9ad9e374-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9ada0df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9ada3608-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9ada5e30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:9ada86ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9adaaf16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9adad7c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9adaffe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9adb2856-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:9adb507e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9adb789c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9adba0a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9adbc98c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9adbf196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9adc19be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9adc42c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9adc6b3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9adc936c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9adcbb80-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9adce39e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9add0c84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9add34a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9add5cc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9add861e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9addb01c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9addd844-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9ade0062-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9ade288a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9ade50ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9ade7916-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9adea120-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9adec9fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9adef1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9adf1a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9adf422e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9adf6b1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9adf933c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9adfbb6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9adfe38c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9ae00be6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9ae034fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9ae05d1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9ae08562-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9ae0ae20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9ae0d648-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:9ae0fe5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9ae1267a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9ae150be-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9ae17bac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9ae1a460-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.29']} DrugCentral uuid:9ae1cc6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9ae1f4ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9ae21ce2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9ae244f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9ae26d00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ae2956e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9ae2bd6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9ae2e582-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9ae30e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9ae336fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9ae35efe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9ae38834-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9ae3b0e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9ae3d938-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9ae4014c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9ae42a96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9ae45304-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9ae47b22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9ae4a336-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9ae4cb54-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9ae4f57a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9ae520d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9ae54bec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:9ae57400-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.49']} DrugCentral uuid:9ae59cd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9ae5c4fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:9ae5ed04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9ae61518-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9ae63d86-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9ae665a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9ae68db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9ae6b658-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9ae6de9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9ae706d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9ae72f16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9ae757a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9ae77fd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:9ae7a7e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9ae7cff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:9ae7f892-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9ae82196-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9ae849be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9ae87268-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9ae89b30-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9ae8c34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ae8eb6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9ae9139e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9ae93c20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9ae9643e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9ae98d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9ae9b5a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9ae9de8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9aea06a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9aea2ea0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9aea56be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.11']} DrugCentral uuid:9aea7f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9aeaa7a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9aeacfae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9aeaf7ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9aeb2012-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9aeb481c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9aeb7030-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9aeb98d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9aebc0f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9aebe916-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9aec121a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9aec3b78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9aec66ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9aec9122-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9aecbd32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9aecbd32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9aecf482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:9aecf482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:9aed2ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9aed2ba0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9aed5ecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:4360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrimide targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9aed8780-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:9aedafb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9aedd7b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9aedffd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:4362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chiniofon targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9aee2a14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:9aee5232-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9aee7a50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZV8 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9aeea282-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.875']} DrugCentral uuid:9aeecb86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9aeef3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9aef1bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9aef45ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:9aef6dfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:9aef9624-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9aefbf32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:9aefe8a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:9af013c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:9af03c00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9af0640a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9af08c96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9af0b4c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9af0dce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9af104f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29973 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9af12dae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16280 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Cyclic nucleotide-gated olfactory channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9af155cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:4379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 degarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:9af17e3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.325']} DrugCentral uuid:9af1a68a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:9af1d18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9af1fba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.95']} DrugCentral uuid:9af223da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirabegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.65']} DrugCentral uuid:9af24bf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9af274a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9af29cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9af2c510-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9af2ee1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9af31646-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9af33e5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9af36682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9af39058-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9af3b876-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9af3e0bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9af40952-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9af43698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9af43698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9af46e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:9af46e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:9af4a740-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9af4a740-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9af4a740-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9af4a740-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9af4f2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9af52684-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9af52684-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9af52684-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9af52684-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9af57530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:9af57530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:9af5b00e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9af5b00e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9af5b00e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9af5ee52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9af6176a-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:9af63f7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:9af66882-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9af690a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:9af6b54e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9af6dd76-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:9af70134-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:9af724fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.582']} DrugCentral uuid:9af74f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.639']} DrugCentral uuid:9af7772c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.321']} DrugCentral uuid:9af79f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.024']} DrugCentral uuid:9af7c786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.029']} DrugCentral uuid:9af7f080-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.154']} DrugCentral uuid:9af818a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.335']} DrugCentral uuid:9af840a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:9af8692a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofenotane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:9af891b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9af8b9de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltrombopag targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9af8e1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9af90b3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casopitant targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:9af93364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casopitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:9af95b8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7DHH4 biolink:molecularly_interacts_with DrugCentral:4402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftobiprole medocaril targets Enzyme (MecA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9af98396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61073 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is partial agonist of GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9af9add0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:9af9d5da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48061 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets Cytokine (Stromal cell-derived factor 1) DrugCentral uuid:9af9f9ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is antagonist of GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9afa21c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08565 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9afa4a9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25106 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is agonist of GPCR (Atypical chemokine receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9afa7422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.118']} DrugCentral uuid:9afa9c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.157']} DrugCentral uuid:9afac45e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:9afaee8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.308']} DrugCentral uuid:9afb16ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:9afb3ed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.915']} DrugCentral uuid:9afb66f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:9afb8f92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:9afbb7ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.085']} DrugCentral uuid:9afbdfe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.478']} DrugCentral uuid:9afc07f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:9afc30b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.262']} DrugCentral uuid:9afc58c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:9afc8104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:9afca918-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:9afcd302-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.781']} DrugCentral uuid:9afcfb0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:9afd233e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.931']} DrugCentral uuid:9afd4ba2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9afd7708-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9afd9f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9afdc73a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibutylphthalate is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9afdefb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9afe17da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9afe40f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9afe6924-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:9afe921e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.018']} DrugCentral uuid:9afeba46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.652']} DrugCentral uuid:9afee246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:9aff0a5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.604']} DrugCentral uuid:9aff32d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.775']} DrugCentral uuid:9aff5afa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9aff844e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9affad48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9affd5f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9afffe24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:9b00264c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9b004e4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9b0078b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9b00a0c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9b00c8d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9b00f0e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9b011976-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9b01454a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9b01454a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9b017c68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:9b017c68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:9b01b5ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9b01b5ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9b01b5ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9b01b5ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9b020066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:9b0235b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9b0235b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9b0235b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9b0235b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9b028356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:9b028356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:9b02be34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9b02be34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9b02be34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9b02fcd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9b03250e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:9b035100-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9b035100-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9b038878-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:9b038878-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:9b03bfbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:9b03bfbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:9b03f2f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone sodium phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9b041a90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.179']} DrugCentral uuid:9b0442d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Cytosolic other (Annexin A1) DrugCentral uuid:9b04669e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9b048eb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:9b04b748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9b04df5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.818']} DrugCentral uuid:9b05086a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9b05306a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:9b05596e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9b058196-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone cypionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:9b05a55e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9b05c926-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:4456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone succinate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9b05f3ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:9b061796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9b063fb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:9b0667d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9b069040-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:4466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eosin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9b06b82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:4466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eosin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:9b06f6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:9b06f6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:9b06f6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:9b06f6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:9b06f6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:9b06f6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:9b06f6e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:9b076150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosaprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9b07898c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9b07b2ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:9b07db58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9b080434-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:9b082c5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:4480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium phosphate, monobasic targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9b0854c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9b08856c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:9b08856c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:9b08856c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:9b08cb94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9b08cb94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9b08cb94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9b09134c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:9b09134c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:9b09134c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:9b094aa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9b0972ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9b099cd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9b09c4f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:9b09ed1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:9b0a1530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9b0a3d9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:9b0a65bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9b0a8dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9b0ab5ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9b0adf06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:9b0b071a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9b0b2f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9b0b58e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9b0b821c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9b0baa30-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9b0bd276-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4485 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflorasone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.536']} DrugCentral uuid:9b0bfc10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4485 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflorasone diacetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:9b0c2460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9b0c4846-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:9b0c7078-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:9b0c98dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:9b0cc0fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9b0ce936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol acetate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:9b0d0cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9b0d360c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:9b0d59f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:9b0d7db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:9b0da5ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:9b0dce50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:9b0df646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:9b0e1a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:9b0e3ed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:9b0e62fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9b0e8b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4504 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9b0eaf32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:9b0ed778-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:9b0f00ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9b0f2b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9b0f534c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.135']} DrugCentral uuid:9b0f7b6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:9b0fa3ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.917']} DrugCentral uuid:9b0fcc0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9b0ff52c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:9b101d54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9b104a5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:9b104a5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:9b1077f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:9b109bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9b10c3f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49190 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9b10eee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P70555 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9b111808-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25961 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b11403a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracosactide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.19']} DrugCentral uuid:9b116876-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracosactide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:9b119102-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:9b11b4f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9b11dd24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:9b12010a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92953 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine is blocker of Ion channel (Potassium voltage-gated channel subfamily B member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9b12298c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:9b12593e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9b12593e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9b12593e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9b129764-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:9b12c252-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbendazole targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.496']} DrugCentral uuid:9b12ed9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:4536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbendazole targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:9b1317ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.12']} DrugCentral uuid:9b133fc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:9b136842-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9b139164-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:9b13ba9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9b13e33a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9b140b58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9b143394-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9b145bbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9b14854c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9b14b8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9b14b8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9b14b8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9b14b8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9b1509f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9b1509f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9b1509f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9b154c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:9b154c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:9b1579f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6RY99 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate targets Unclassified (Gamma-hydroxybutyrate receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9b15a210-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochloric acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9b15cab0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone probutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9b15ef04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9b161718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9b163f22-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9b166934-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9b169cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b169cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b169cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b169cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b16e7a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9b171032-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9b17386e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9b176096-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88944 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9b1788c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9b17b140-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9b17d95e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9b180168-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9b182ad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:9b1852f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9b187b0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9b18a320-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tonzonium targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:9b18cc9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:4605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tonzonium targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9b18f4b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clocortolone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9b1918a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:4608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9b1940be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:4608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:9b196936-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone enantate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:9b198d12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9b19b530-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9b19dd44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9b1a06e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9b1a2f06-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9b1a5738-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27471 biolink:molecularly_interacts_with DrugCentral:4615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 N-Acetylglucosamine targets Unclassified (Killer cell lectin-like receptor subfamily B member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b1a8064-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9b1aa8fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9b1ad118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:9b1af972-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9b1b2190-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9b1b4ab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9b1b72d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9b1b9ae4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:9b1bc302-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b1bee9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.56']} DrugCentral uuid:9b1c19f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9b1c426e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9b1c6aaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9b1c9336-dc5e-11ec-be2c-0242ac110005 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:9b1cbb40-dc5e-11ec-be2c-0242ac110005 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:9b1ce37c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9b1d0bea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:9b1d341c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9b1d5c1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:4621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomefolic acid targets Enzyme (Thymidylate synthase) DrugCentral uuid:9b1d7ff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23897 biolink:molecularly_interacts_with DrugCentral:4622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:9b1da988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:4622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.907']} DrugCentral uuid:9b1de8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:9b1de8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:9b1de8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:9b1de8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:9b1de8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:9b1de8da-dc5e-11ec-be2c-0242ac110005 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:9b1e3f2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:4624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylacetic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:9b1e67ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:9b1e8ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:9b1eb828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:9b1ee122-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:9b1f0968-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9b1f319a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:9b1f5d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9b1f5d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9b1f92c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4628 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enzalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9b1fbaca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4628 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enzalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:9b1fe2de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium pyrophosphate targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:9b200b1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:9b203aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9b203aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9b203aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9b203aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:9b207bea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trabectedin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9b20a41c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:4633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trabectedin is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9b20cd3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9b20f584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9b211da2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9b2145c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:9b21702c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9b21985e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:4635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Choline C-11 targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9b21c16c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9b21e994-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9b2211f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9b223a16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9b2262ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O06446 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9b228b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2FUW6 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b22b3d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9b22dc00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:9b23040a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9b232dcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9b23582e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9b23816e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9b23a9be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9b23d22c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9b23fa2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid is agonist of GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9b242240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:9b244a68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9b2472cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:9b249afe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:9b24c312-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9b24eb1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b251560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:9b253d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b25659c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9b258f54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9b25b7d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b25dffe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9b26081c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b26306c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b2658bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9b2680e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b26a8ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b26d292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b26fd12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b27253a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b274d58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b2775c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b279dbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b27c602-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9b27ee16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b281698-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:4655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedisamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:9b283eca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metamizole is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.041']} DrugCentral uuid:9b2866e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:9b288f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9b28b990-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:9b28e1cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:9b2909ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:4663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoin targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9b29321c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:4663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoin targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:9b295ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:9b2984e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b29ad00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9b29d532-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:9b29fdbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.776']} DrugCentral uuid:9b2a25fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:9b2a4e2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:9b2a7794-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:9b2aa20a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.428']} DrugCentral uuid:9b2aca14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:9b2af2aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:9b2b1b18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:9b2b4322-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9b2b6b4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9b2b9372-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:9b2bbbc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:9b2be3c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:9b2c0be0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9b2c33e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9b2c5d70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:9b2c858e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9b2cadb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:9b2cd5d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:9b2cfe56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:9b2d2688-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9b2d4f78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:9b2d77a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9b2da02c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9b2dc868-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9b2df086-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:9b2e18c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obidoxime targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.67']} DrugCentral uuid:9b2e43d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9b2e6be2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9b2e9400-dc5e-11ec-be2c-0242ac110005 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9b2ebc6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9b2ee4b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:9b2f0cfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9b2f3658-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:9b2f5f16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9b2f8766-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:9b2fafac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9b2fd7fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:9b30020e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9b302c5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9b30552e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:9b307d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:9b30a5b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9b30cdc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9b30f632-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9b311e50-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:9b3147cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9b316fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b3197ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O35678 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b31bffe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O08914 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9b31f686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:9b31f686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:9b31f686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:9b31f686-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:9b323fce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9b326828-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9b329050-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7T664 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9b32b878-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:4696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remikiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:9b32e08c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9b33090e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9b33314a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:9b33594a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:9b33817c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:9b33ab48-dc5e-11ec-be2c-0242ac110005 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9b33d352-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 semustine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:9b33fb8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.074']} DrugCentral uuid:9b3423ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:9b3447ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.624']} DrugCentral uuid:9b346fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:9b349800-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9b34c172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:4710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatorelin is agonist of GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9b34eabc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:9b3512ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9b353b20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9b35633e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9b358e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9b35b8e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b35e2d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9b360b90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:9b363458-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b365c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9b368494-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9b36ad16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9b36d534-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9b36fd66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9b37258e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9b374f00-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9b37773c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9b379f64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9b37c78c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b37f02c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:9b38184a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9b384068-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9b38e11c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9b390e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9b39390a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:9b3962e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b398b12-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9b39b34e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9b39dc48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9b3a0466-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9b3a2ca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9b3a5524-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62137 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9b3a7d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9b3aa588-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:9b3acdba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b3afb78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:9b3afb78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:9b3b3c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9b3b3c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9b3b3c32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9b3b7eae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9b3b7eae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9b3bb284-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63272 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b3bde8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:9b3bde8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:9b3c1670-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:9b3c1670-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:9b3c4a1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.907']} DrugCentral uuid:9b3c723c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:9b3c9a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9b3cc37c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9b3cef32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9b3d1a66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:9b3d4590-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9b3d7056-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:9b3d9874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9b3dc0ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:9b3de8e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.947']} DrugCentral uuid:9b3e1150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:9b3e3982-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.456']} DrugCentral uuid:9b3e61b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.845']} DrugCentral uuid:9b3e89f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.886']} DrugCentral uuid:9b3eb498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9b3edfd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:9b3f09ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.903']} DrugCentral uuid:9b3f31f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Breakpoint cluster region protein) DrugCentral uuid:9b3f56d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9b3f7ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9b3fa70e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9b3fcf40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:9b3ff7ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9b401fd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:9b4047e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.268']} DrugCentral uuid:9b4070ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:9b409bbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:9b40c3fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9b40ec22-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:9b4114ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9b413d12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9b41653a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.17']} DrugCentral uuid:9b418d8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9b41b5f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9b41e1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9b41e1c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9b421520-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9b423dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95838 biolink:molecularly_interacts_with DrugCentral:4718 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teduglutide is agonist of GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:9b4266ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z0W0 biolink:molecularly_interacts_with DrugCentral:4718 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teduglutide targets GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:9b428ece-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:9b42b2a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:9b42d668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:9b42fad0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:9b431ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:9b434274-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55157 biolink:molecularly_interacts_with DrugCentral:4721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomitapide is inhibitor of Cytosolic other (Microsomal triglyceride transfer protein large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:9b436ab0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinimide targets Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:9b43933c-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinimide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9b43bb50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:4727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9b43e382-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.573']} DrugCentral uuid:9b440b8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9b443670-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:9b445f6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9b44886e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9b44b082-dc5e-11ec-be2c-0242ac110005 UniProtKB:O97554 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9b44d9ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O02768 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9b450582-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9b450582-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9b4538b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48050 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap is activator of Ion channel (Inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4599e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b46749e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:9b46749e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:9b46749e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:9b46bc88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:9b46bc88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:9b46bc88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:9b4702b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:9b4702b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:9b4702b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:9b474162-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9b476d72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9b476d72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9b47a0b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9b47c998-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:9b47f1d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:9b4819e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:9b48421a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:9b486b28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:9b48935a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:9b48bb82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.135']} DrugCentral uuid:9b48e3be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:9b490c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:9b493454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9b495c7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9b4984a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9b49af2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9b49dbac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9b4a06f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b4a2f12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b4a57f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9b4a803e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9b4aa87a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:9b4ad0e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9b4af92e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:9b4b212e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4b63a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:9b4bce3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5TIX5 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9b4bf658-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00845 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9b4c1eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crofelemer is inhibitor of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:9b4c4720-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5XXA6 biolink:molecularly_interacts_with DrugCentral:4744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crofelemer is inhibitor of Ion channel (Anoctamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:9b4c6f3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9b4c977a-dc5e-11ec-be2c-0242ac110005 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9b4cc02e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.577']} DrugCentral uuid:9b4ce84c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ospemifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.082']} DrugCentral uuid:9b4d1088-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobetaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9b4d38c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobetaxolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9b4d63a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:4757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyl fumarate targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9b4d8cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14145 biolink:molecularly_interacts_with DrugCentral:4757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyl fumarate is inhibitor of Cytosolic other (Kelch-like ECH-associated protein 1) DrugCentral uuid:9b4db0c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:9b4dd964-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9b4e01fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9b4e2a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9b4e5272-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:9b4e7ae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9b4ea330-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:9b4ecb30-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9b4ef498-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9b4f1e8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9b4f4920-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9b4f7184-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4778 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ridaforolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:9b4f998e-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.289']} DrugCentral uuid:9b4fc210-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:9b4fea2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.961']} DrugCentral uuid:9b501242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.477']} DrugCentral uuid:9b503a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:9b5062ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:9b508aec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:9b50b314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:9b50db3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium propionate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:9b510486-dc5e-11ec-be2c-0242ac110005 UniProtKB:B2GV46 biolink:molecularly_interacts_with DrugCentral:4796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium propionate targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9b512ca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.2']} DrugCentral uuid:9b5154e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.08']} DrugCentral uuid:9b517e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.9']} DrugCentral uuid:9b51a6ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9b51ced4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9b51f6d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9b521ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9b524792-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:9b526fe2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:9b52980a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9b52c186-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:9b52ecd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:9b5315a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9b533e36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9b536690-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b538eae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:9b53b6d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:9b53df08-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:9b54078a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b542fa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:9b5457c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:9b548002-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.036']} DrugCentral uuid:9b54a91a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:9b54d25a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4804 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palifermin is agonist of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:9b54f640-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9b551e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9b554816-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9b55705c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:9b55985c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9b55c0ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.131']} DrugCentral uuid:9b55e92e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9b56116a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9b5639a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9b5661ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9b568d70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9b56b796-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9b56dfdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9b5708a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9b5730e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9b5758f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9b57811c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9b57a99e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9b57d1c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:9b57f9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:9b58222a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:9b584c1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:9b58754a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:9b589e6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:9b58c6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:9b58ef8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:4807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riociguat targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:9b5917de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riociguat is positive allosteric modulator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'MEC', 'has_quantitative_value': ['7.523']} DrugCentral uuid:9b5940f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9b5968f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9b59916e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9b59b98c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.658']} DrugCentral uuid:9b59e1a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.569']} DrugCentral uuid:9b5a09e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macitentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:9b5a348e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macitentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.408']} DrugCentral uuid:9b5a5cc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9b5a852e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9b5aadce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:9b5ad718-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9b5aff9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:9b5b27b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9b5b508a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9b5b7894-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9b5ba0ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9b5bc916-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRX8 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Unclassified (Redox-regulatory protein FAM213A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9b5bf2ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:9b5c1cc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:9b5c44ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:9b5c6d08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:9b5c95c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:9b5cbdee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:9b5ce616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:9b5d0ede-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:9b5d3864-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:9b5d60a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:9b5d88d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9b5db104-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:9b5ddb5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9b5e038e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:9b5e2bc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.143']} DrugCentral uuid:9b5e5410-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofosbuvir is inhibitor of Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9b5e7d5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofosbuvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC90', 'has_quantitative_value': ['6.959']} DrugCentral uuid:9b5ea58c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9b5ed21e-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9b5ed21e-dc5e-11ec-be2c-0242ac110005 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9b5f05cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:9b5f2dea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6GYR8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Polyprotein (Polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:9b5f5630-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:9b5f7e6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:4813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luliconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:9b5fa34c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:9b5fcb88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9b5ff3d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:9b601c14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lixisenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.845']} DrugCentral uuid:9b6044b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9b606cf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:9b609662-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:9b60bebc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.824']} DrugCentral uuid:9b60e7ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:9b6110ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b613914-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b616150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9b618d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9b61b59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:9b61d964-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 florbetaben F18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:9b620204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:4820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:9b622a4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:4820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9b625290-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 seractide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.009']} DrugCentral uuid:9b627acc-dc5e-11ec-be2c-0242ac110005 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9b62a3a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:4822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9b62cbda-dc5e-11ec-be2c-0242ac110005 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9b62f3f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:9b631c16-dc5e-11ec-be2c-0242ac110005 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9b6345a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9b636e3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:9b63966e-dc5e-11ec-be2c-0242ac110005 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9b63be5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b63e6f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:9b640f36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9b643790-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9IGQ6 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:9b645fd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilefrine pivalate is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:9b648484-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48357 biolink:molecularly_interacts_with DrugCentral:4826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metreleptin is agonist of Membrane receptor (Leptin receptor) DrugCentral uuid:9b64a874-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9b64d092-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9b64f8b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:9b6523b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:9b654c98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M3M2 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:9b6574ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0PJK1 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:9b659ce8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.081']} DrugCentral uuid:9b65c54c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:9b65ee0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.244']} DrugCentral uuid:9b661646-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxegol is antagonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:9b663a36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemigliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.328']} DrugCentral uuid:9b666434-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:9b668c7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:4834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eliglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.827']} DrugCentral uuid:9b66b498-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9b66dcca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9b6705e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9b672df6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:9b675628-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33033 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9b677e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41149 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9b67a68c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56450 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:9b67ce96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01727 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:9b67f6aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:9b681f9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprotinin is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9b6847ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprotinin is inhibitor of Enzyme (Plasma kallikrein) DrugCentral uuid:9b686bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ecallantide is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.602']} DrugCentral uuid:9b689434-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:4848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatropin is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:9b68b8b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:4853 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cridanimod targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9b68e0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3TBT3 biolink:molecularly_interacts_with DrugCentral:4853 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cridanimod targets Unclassified (Stimulator of interferon genes protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9b690914-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:9b692e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:9b6951ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:9b697a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9b69a2d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:9b69c6c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:9b69eaa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q60748 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9b6a137c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47866 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9b6a3bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13324 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9b6a63ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34998 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.481']} DrugCentral uuid:9b6a90f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:9b6a90f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:9b6ac1e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9b6aea36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:9b6b2a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b6b2a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b6b2a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b6b2a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b6b2a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b6b2a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b6b2a0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9b6b9620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.951']} DrugCentral uuid:9b6bbe52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.035']} DrugCentral uuid:9b6be7a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:9b6c0b6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:9b6c2f36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9b6c574a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9b6c8242-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9b6caa60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9b6cd27e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9b6cfa88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9b6d236e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9b6d4b8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9b6d7396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9b6d9c04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9b6dc422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9b6dec40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:9b6e1454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9b6e3dbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9b6e6652-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9b6e8e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:9b6eb67a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9b6edf10-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9b6f072e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9b6f2f4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:9b6f5760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9b6f7fd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9b6fa7ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:9b6fcfce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:9b6ff7d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9b70223a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9b704a76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9b707370-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9b709b98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9b70c474-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9b70ec92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41212 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transcription factor (Transcription factor ETV6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9b7114ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9b713d6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:9b71674e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:9b718f76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:9b71b7a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:9b71e084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9b720a46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9b723278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9b725abe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9b7283ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9b72abe0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9b72d412-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9b72fc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:9b7324b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9b734ce4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9b7378d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:9b7378d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:9b73a680-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25116 biolink:molecularly_interacts_with DrugCentral:4870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorapaxar is antagonist of GPCR (Proteinase-activated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.092']} DrugCentral uuid:9b73d18c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9b73faf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9b742308-dc5e-11ec-be2c-0242ac110005 UniProtKB:F2SHH3 biolink:molecularly_interacts_with DrugCentral:4874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efinaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:9b7447b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:9b747074-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:9b749892-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:9b74c0ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:9b74e8d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.301']} DrugCentral uuid:9b751146-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:9b753996-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:9b7561c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:9b758ae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9b75b3d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9b75dca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:9b7604f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9b762dc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9b7655e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:9b767e1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:9b76a628-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9b76ce82-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9b76f682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.569']} DrugCentral uuid:9b771fb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9b7747e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b777238-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9b779c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9b77c472-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26637 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Leucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:9b77ec86-dc5e-11ec-be2c-0242ac110005 UniProtKB:F2SF18 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole is inhibitor of Enzyme (Leucine-tRNA ligase) DrugCentral uuid:9b7810e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9b7839fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NEB9 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 3-kinase catalytic subunit type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9b786238-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.086']} DrugCentral uuid:9b788a60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.248']} DrugCentral uuid:9b78b2f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.051']} DrugCentral uuid:9b78db28-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:9b790364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:4879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxaparin sodium is activator of Secreted (Antithrombin-III) DrugCentral uuid:9b792740-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58308 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant targets GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:9b795170-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58307 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:9b7979b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9b79a210-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:9b79ca42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9b79f332-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9b7a1b64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9b7a43a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9b7a6c9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9b7a94c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9b7abcd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9b7ae51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:9b7b0eac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dulaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) DrugCentral uuid:9b7b33fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:4886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetilistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.225']} DrugCentral uuid:9b7b5c04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:4888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiroxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:9b7b8422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:4888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiroxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.276']} DrugCentral uuid:9b7bacd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:4889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asunaprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9b7bd4e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asunaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:9b7bfd76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9b7c268e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8C3K6 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:9b7c4ef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53790 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:9b7c772e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q923I7 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:9b7c9f2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.727']} DrugCentral uuid:9b7cc756-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.132']} DrugCentral uuid:9b7cf208-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luseogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.399']} DrugCentral uuid:9b7d1a44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luseogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.646']} DrugCentral uuid:9b7d4258-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4892 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.073']} DrugCentral uuid:9b7d6a6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4892 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:9b7d9398-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07650 biolink:molecularly_interacts_with DrugCentral:4893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipiracil targets Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9b7dbbde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19971 biolink:molecularly_interacts_with DrugCentral:4893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipiracil is inhibitor of Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:9b7de3f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:4894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iguratimod targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9b7e0c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.54']} DrugCentral uuid:9b7e3474-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:9b7e5c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:9b7e84b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:9b7eacce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:9b7ed76c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:9b7eff76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:9b7f279e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9b7f50e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edoxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.252']} DrugCentral uuid:9b7f791a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4898 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:9b7fa14c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:9b7fc94c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:9b7ff1ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:9b801ad2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.509']} DrugCentral uuid:9b8042f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:4900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9b806b0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:4900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:9b8094da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin glargine is agonist of Kinase (Insulin receptor) DrugCentral uuid:9b80b938-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidafenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['8.384']} DrugCentral uuid:9b80e160-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidafenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['9.499']} DrugCentral uuid:9b810988-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:9b81325a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:9b815a8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:9b8182b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9b81aac8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9b81d340-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:9b81fb54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9b82237c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:9b824b86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9b8275b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9b829dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9b82c700-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.38']} DrugCentral uuid:9b82ef1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.02']} DrugCentral uuid:9b8317e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9b833ffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9b83682c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9b839040-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9b83b8a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9b83e0ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9b8409b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9b8432d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9b845e26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9b848860-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9b84b09c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9b84d946-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9b8501f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9b852a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:9b855236-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9b857aae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9b85a2c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:9b85cacc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9b85f2fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9b861f54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9b864768-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9b866f7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9b869786-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9b86bff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9b86e81c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9b871044-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9b873862-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9b8760e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9b8788f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9b87b0f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9b87da38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9b8805f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9b882f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9b885742-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9b887fb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9b88a7c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b88d12c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9b88f954-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:9b8921c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9b8949e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9b8971ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9b8999f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9b89c460-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9b89ee68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9b8a167c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9b8a3e86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9b8a6762-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.66']} DrugCentral uuid:9b8a8f6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9b8ab780-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:9b8adf94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9b8b0820-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9b8b308e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9b8b58a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9b8b80ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9b8baa5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9b8bd2e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9b8bfbf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9b8c24d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9b8c4cf8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.29']} DrugCentral uuid:9b8c750c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9b8c9d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9b8cc5ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9b8cedca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9b8d15b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9b8d3de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9b8d67dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9b8d92e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9b8dbc28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9b8de432-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9b8e0ce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9b8e3504-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9b8e5d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9b8e852c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:9b8eaec6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9b8ed6ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9b8eff02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9b8f2716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9b8f5286-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9b8f7ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9b8fa39e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9b8fcc52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9b8ff542-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9b901d74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9b9046be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9b906f36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9b90974a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9b90bf5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9b90e77c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9b911094-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9b9138bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9b9160e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9b918902-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9b91b1ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9b91d9e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9b920210-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9b922a24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9b9252ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9b927b5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9b92a378-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9b92cb8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9b92f6ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:9b93212c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9b93494a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9b9371e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9b939a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9b93c212-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9b93eb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9b9413b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9b943be8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9b9463f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:9b948c10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9b94b9c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9b94e3a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9b950bc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b9533ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9b955c58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9b958476-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9b95ac80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9b95d49e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9b95fd02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9b962520-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9b964d3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9b967552-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:9b969e60-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9b96c674-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9b96ee92-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9b9716a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:9b973f1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9b976728-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9b978f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9b97b890-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9b97e0a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9b9808c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:9b9830ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9b985a48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9b988270-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b98aa84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9b98d28e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.07']} DrugCentral uuid:9b98fafc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9b99239c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9b994bc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9b9973e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:9b999cf0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9b99c4fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9b99ed18-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9b9a1522-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9b9a3f20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9b9a673e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9b9a915a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9b9ab978-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9b9ae1dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b9b0a04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9b9b3204-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9b9b5a22-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9b9b829a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9b9bab9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b9bd3bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9b9bfc98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9b9c26c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9b9c4ee6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9b9c76fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9b9c9f72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9b9cc79a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9b9cefcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9b9d17d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9b9d4044-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9b9d684e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9b9d9076-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9b9db88a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9b9de21a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9b9e0a38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b9e324c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9b9e5a7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9b9e82f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9b9eab1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9b9ed332-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9b9efb32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9b9f23aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9b9f4bd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:9b9f73d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:9b9f9cfe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9b9fc922-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9b9ff1cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9ba019f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9ba04244-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:9ba06a6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9ba093b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9ba0bbd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9ba0e46a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9ba10c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9ba1349c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9ba15ca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9ba185c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9ba1add2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9ba1d5e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9ba1fdfa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:9ba22668-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9ba24e72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9ba27690-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9ba29ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9ba2c730-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9ba2ef58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9ba3176c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9ba33f76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:9ba36a5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9ba39278-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:9ba3baaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.983']} DrugCentral uuid:9ba3e2d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9ba40b54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9ba43372-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9ba45bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9ba483d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adalimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:9ba4a83e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4905 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegaptanib is antagonist of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:9ba4cc1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fimasartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.377']} DrugCentral uuid:9ba4f442-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9ba51c60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9ba5465e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9ba56e7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9ba596ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9ba5beae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2NL67 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Unclassified (Poly [ADP-ribose] polymerase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9ba5e726-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5Y8 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Unclassified (Mono [ADP-ribose] polymerase PARP16) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9ba60f1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:9ba63730-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9ba66142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9ba6897e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9ba6b1a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acotiamide is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:9ba6d9c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31358 biolink:molecularly_interacts_with DrugCentral:4909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alemtuzumab is antibody binding of Surface antigen (CAMPATH-1 antigen) DrugCentral uuid:9ba6ff12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4910 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felypressin is agonist of GPCR (Vasopressin V1a receptor) DrugCentral uuid:9ba7233e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.85']} DrugCentral uuid:9ba74b66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.92']} DrugCentral uuid:9ba7746a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.301']} DrugCentral uuid:9ba79cec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:9ba7c50a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasabuvir targets Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9ba7ecf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasabuvir targets Unclassified (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9ba8151e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:9ba845f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9ba845f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9ba845f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9ba8847c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:9ba8acc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49763 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Placenta growth factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.409']} DrugCentral uuid:9ba8d666-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49765 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.717']} DrugCentral uuid:9ba8ff10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4917 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramucirumab is antibody binding of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9ba9274c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:9ba94f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9ba977b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:9ba9a0aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9ba9d066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9ba9d066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9ba9d066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9baa0f90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:9baa37c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nivolumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.14']} DrugCentral uuid:9baa601c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pembrolizumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:9baa8c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:9baa8c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:9baabc60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:4927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9baae604-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:9bab0e36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:4928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 follitropin is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:9bab3244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:4929 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lutropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.9']} DrugCentral uuid:9bab5aee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16473 biolink:molecularly_interacts_with DrugCentral:4930 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyrotropin alfa is agonist of GPCR (Thyrotropin receptor) DrugCentral uuid:9bab7eca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9baba710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9babd082-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9babf95e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:9bac1d44-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q64326 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9bac495e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:9bac495e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:9bac779e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:4934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secukinumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:9bac9e72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03420 biolink:molecularly_interacts_with DrugCentral:4935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palivizumab is antibody binding of Surface antigen (Fusion glycoprotein F0) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:9bacc6e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4936 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parathyroid hormone is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) DrugCentral uuid:9baceac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9bad1320-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:9bad3b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9bad637a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:9bad8bc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:9badb49c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.319']} DrugCentral uuid:9baddcba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9bae04ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:9bae2d32-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:9bae56b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:9bae7f44-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9baea776-dc5e-11ec-be2c-0242ac110005 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9baed0a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.301']} DrugCentral uuid:9baef99c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:9baf21f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01589 biolink:molecularly_interacts_with DrugCentral:4940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 basiliximab is antibody binding of Membrane receptor (Interleukin-2 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:9baf4a1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9baf7232-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9baf9aaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9bafc6ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9bafc6ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9baffdd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9baffdd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9bb035c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9bb035c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9bb06912-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:9bb0913a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:9bb0b958-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:9bb0e23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:9bb10a70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:9bb133ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:9bb15c64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:9bb18496-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:9bb1acd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9bb1d518-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9bb1fe8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.658']} DrugCentral uuid:9bb22716-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:9bb24f48-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:9bb27874-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:9bb2a146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:9bb2c96e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:9bb2f16e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:9bb31a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.947']} DrugCentral uuid:9bb34290-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.538']} DrugCentral uuid:9bb36ac2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:9bb392cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin is agonist of GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9bb3bae0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9bb3e59c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:9bb40dec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9bb4360a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:9bb45e46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9bb4870e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9bb4af36-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.155']} DrugCentral uuid:9bb4d772-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9bb4ffa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9bb52844-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y275 biolink:molecularly_interacts_with DrugCentral:4949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belimumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 13B) DrugCentral uuid:9bb54ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:9bb54ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:9bb57da8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofatumumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.92']} DrugCentral uuid:9bb5a6c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:4952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canakinumab is antibody binding of Cytokine (Interleukin-1 beta) DrugCentral uuid:9bb5d244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9bb5d244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9bb5d244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9bb6109c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetuximab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:9bb639d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panitumumab is agonist of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9bb66308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bevacizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:9bb686ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4957 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pertuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:9bb6aade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16410 biolink:molecularly_interacts_with DrugCentral:4958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipilimumab is antibody binding of Surface antigen (Cytotoxic T-lymphocyte protein 4) DrugCentral uuid:9bb6cffa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:4959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efalizumab is antibody binding of Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.4']} DrugCentral uuid:9bb6f8c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin degludec is agonist of Kinase (Insulin receptor) DrugCentral uuid:9bb71ca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:4961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raxibacumab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.556']} DrugCentral uuid:9bb74584-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28908 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is binding agent of Membrane receptor (Tumor necrosis factor receptor superfamily member 8) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb78a1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bb7fb50-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14788 biolink:molecularly_interacts_with DrugCentral:4965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denosumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 11) DrugCentral uuid:9bb823aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:9bb823aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:9bb85528-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:9bb85528-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:9bb882be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 golimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:9bb8a6b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 certolizumab pegol is antibody binding of Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.046']} DrugCentral uuid:9bb8cf62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:4969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eculizumab is antibody binding of Secreted (Complement C5) DrugCentral uuid:9bb8f712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:9bb8f712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:9bb9289a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:9bb9289a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:9bb95702-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranibizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:9bb97ad4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01854 biolink:molecularly_interacts_with DrugCentral:4972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omalizumab is antibody binding of Antibody (Ig epsilon chain C region) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:9bb9a400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9bb9cc1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide targets Cytokine (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9bb9f4f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.135']} DrugCentral uuid:9bba1d22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.365']} DrugCentral uuid:9bba455e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:9bba6d90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.022']} DrugCentral uuid:9bba9630-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:9bbabe62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.108']} DrugCentral uuid:9bbae69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infliximab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:9bbb0a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rituximab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:9bbb35b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone hexacetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:9bbb599e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:4977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siltuximab is antibody binding of Cytokine (Interleukin-6) DrugCentral uuid:9bbb7d7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4978 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etanercept is inhibitor of Cytokine (Tumor necrosis factor) DrugCentral uuid:9bbba16a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4979 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:9bbbc640-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20138 biolink:molecularly_interacts_with DrugCentral:4980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemtuzumab ozogamicin is antibody binding of Surface antigen (Myeloid cell surface antigen CD33) DrugCentral uuid:9bbbea3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin aspart is agonist of Kinase (Insulin receptor) DrugCentral uuid:9bbc11fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9bbc11fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9bbc455c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obinutuzumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) DrugCentral uuid:9bbc69b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4984 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibritumomab tiuxetan is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.854']} DrugCentral uuid:9bbc920a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin detemir is agonist of Kinase (Insulin receptor) DrugCentral uuid:9bbcb604-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:9bbcd9ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:9bbcfee8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:9bbd2738-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:9bbd4f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:9bbd774c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07445 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid targets Unclassified (Steroid Delta-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9bbda118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbde380-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9bbe5504-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4991 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lipegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:9bbe7cbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9bbe7cbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9bbeb008-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.15']} DrugCentral uuid:9bbeda42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romiplostim is agonist of Membrane receptor (Thrombopoietin receptor) DrugCentral uuid:9bbf0102-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5000 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evolocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.72']} DrugCentral uuid:9bbf2c2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9bbf5760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:9bbf817c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9bbfaab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9bbfd2f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:9bbffb2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:9bc023e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin lispro is agonist of Kinase (Insulin receptor) DrugCentral uuid:9bc047b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:9bc06fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15127 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.71']} DrugCentral uuid:9bc097ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human is agonist of Kinase (Insulin receptor) DrugCentral uuid:9bc0bca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirodenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.469']} DrugCentral uuid:9bc0e4a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9bc10da8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9bc135e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.627']} DrugCentral uuid:9bc15ea2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin theta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:9bc18256-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:5008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sonidegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9bc1aa88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sonidegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:9bc1d2b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecasermin targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:9bc1fb3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecasermin is agonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9bc22454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:9bc25424-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:9bc25424-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:9bc25424-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:9bc28d40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:5012 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacubitril is inhibitor of Enzyme (Neprilysin) DrugCentral uuid:9bc2b108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trelagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:9bc2d980-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9bc301b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:9bc32b06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:9bc353c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:9bc37bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:9bc3a3f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:9bc3cc6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:9bc3f48c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:9bc41cbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:9bc44568-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.857']} DrugCentral uuid:9bc46e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:9bc4969e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:9bc4bea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:9bc4e87e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:9bc510ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9bc539fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9bc5622c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9bc58aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:9bc5b2cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:9bc5daf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:9bc6031c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.025']} DrugCentral uuid:9bc62d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:9bc657ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:9bc67fea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:9bc6a81c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:9bc6d0c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:9bc6f90c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.921']} DrugCentral uuid:9bc7213e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:9bc74970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegvisomant is antagonist of GPCR (Growth hormone receptor) DrugCentral uuid:9bc76df6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alirocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:9bc799e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9bc799e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9bc7cd14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:9bc7f690-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.516']} DrugCentral uuid:9bc81fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:9bc84820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:9bc87066-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.049']} DrugCentral uuid:9bc898fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:9bc8c246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.093']} DrugCentral uuid:9bc8ea96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9bc91368-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9bc9402c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9bc9402c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9bc9777c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:9bc9777c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:9bc9a51c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolapitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:9bc9ce0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:5031 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mogamulizumab is antibody binding of GPCR (C-C chemokine receptor type 4) DrugCentral uuid:9bc9f1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9bca1a4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:9bca426a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9bca6b00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9bca931e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9bcabc5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9bcae486-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9bcb0d62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:9bcb359e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:9bcb5de4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.07']} DrugCentral uuid:9bcb862a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:9bcbafa6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9bcbd7e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:9bcc0028-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:9bcc2864-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:9bcc50fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:9bcc7922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9bcca24e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9bccca6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9bccf33e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9bcd1b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9bcd4352-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9bcd6b70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9bcd9564-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9bcdbd82-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9bcde5c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9bce0e40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9bce3668-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9bce5eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9bce8712-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:9bceafa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9bced7d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6XA80 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Unclassified (Leukotriene C4 synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9bceffda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatrem is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:9bcf23a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:9bcf48aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:9bcf728a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib is allosteric modulator of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9bcf9abc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:9bcfc2d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.187']} DrugCentral uuid:9bcfeb52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:9bd01352-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9bd03b5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:9bd0637a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9bd08d0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9bd0b64a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9bd0de4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9bd10668-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9bd13048-dc5e-11ec-be2c-0242ac110005 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9bd15866-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9bd1807a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9bd1a8d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:9bd1d1ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9bd1fa0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9bd22232-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9bd24a6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9bd27354-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9bd29b86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9bd2c39a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9bd2ec8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:9bd317d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:9bd34004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:9bd36822-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:9bd390ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:9bd3b8f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.469']} DrugCentral uuid:9bd3e14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:9bd40a16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.469']} DrugCentral uuid:9bd432de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:9bd45ade-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:9bd48428-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:9bd4ac78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin glulisine is agonist of Kinase (Insulin receptor) DrugCentral uuid:9bd4d1bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lusutrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.076']} DrugCentral uuid:9bd4f9a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5060 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9bd521c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:5060 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9bd549f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepolizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:9bd57284-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:9bd59a84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9bd5c298-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9bd5eaa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9bd61360-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53634 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Enzyme (Dipeptidyl peptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:9bd63b92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9bd664e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:9bd68d0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daratumumab is antibody binding of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9bd6b7ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 climbazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9bd6dfc0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trenbolone hexahydrobenzylcarbonate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:9bd707e8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trenbolone hexahydrobenzylcarbonate targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:9bd7304c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenecteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:9bd7543c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.509']} DrugCentral uuid:9bd77c50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:9bd7a4a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:9bd7cd4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:5068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivaracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9bd7f59a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:5068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivaracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9bd81de0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 necitumumab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.49']} DrugCentral uuid:9bd84626-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQ25 biolink:molecularly_interacts_with DrugCentral:5072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elotuzumab is antibody binding of Membrane receptor (SLAM family member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9bd8701a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:5075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.432']} DrugCentral uuid:9bd898e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.137']} DrugCentral uuid:9bd8c10a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9bd8e93c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9bd911b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9bd939dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9bd96204-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:9bd98a2c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9bd9b308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:9bd9db4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:9bda0362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:9bda2b76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:9bda542a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:9bda7c3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.523']} DrugCentral uuid:9bdaa452-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:9bdacc70-dc5e-11ec-be2c-0242ac110005 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:9bdaf524-dc5e-11ec-be2c-0242ac110005 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:9bdb1d38-dc5e-11ec-be2c-0242ac110005 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:9bdb4560-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9bdb6d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.301']} DrugCentral uuid:9bdb9628-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.398']} DrugCentral uuid:9bdbbe46-dc5e-11ec-be2c-0242ac110005 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:9bdbe664-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:5083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixekizumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:9bdc11de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:9bdc11de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:9bdc11de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:9bdc4c12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06729 biolink:molecularly_interacts_with DrugCentral:5088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alefacept is inhibitor of Surface antigen (T-cell surface antigen CD2) DrugCentral uuid:9bdc6ff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9bdc982a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9bdcc0c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) DrugCentral uuid:9bdce596-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) DrugCentral uuid:9bdd0a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5093 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reslizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.092']} DrugCentral uuid:9bdd3244-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:5094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obiltoxaximab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.481']} DrugCentral uuid:9bdd5b34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01583 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.854']} DrugCentral uuid:9bdd8366-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18510 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Unclassified (Interleukin-1 receptor antagonist protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.215']} DrugCentral uuid:9bddab98-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:9bddd3d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urokinase is activator of Enzyme (Plasminogen) DrugCentral uuid:9bddf882-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9bde2082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9bde488c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9bde708c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9bde98f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9bdec0f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:9bdee8f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:9bdf10e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59750 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9bdf399a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02401 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:9bdf61a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UUZ4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Alpha-galactosidase C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:9bdf89a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q42656 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Alpha-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9bdfb1ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:D3ZUM4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:9bdfdb16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8VNN2 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:9be00348-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06280 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat is pharmacological chaperone of Enzyme (Alpha-galactosidase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9be02c42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chromic chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:9be05456-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chromic chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:9be07ce2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:9be0a50a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:9be0cd46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:9be0fa78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be0fa78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be12bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be12bd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be15d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be15d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be18c0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:9be1b0a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9be1d902-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9be20148-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9be2297a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O88587 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9be2522e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:9be27a38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:5144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gluconolactone targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:9be2a256-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:5149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choriogonadotropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:9be2c628-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atezolizumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:9be2ef04-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:9be317a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:9be33fc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.796']} DrugCentral uuid:9be368d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:9be392d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.979']} DrugCentral uuid:9be3baec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:9be3e404-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:9be40c90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9DHD6 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:9be434b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O91936 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.426']} DrugCentral uuid:9be45cf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5I2N3 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.097']} DrugCentral uuid:9be48512-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:5155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obeticholic acid targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9be4add0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:5155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obeticholic acid is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.004']} DrugCentral uuid:9be4d5f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darbepoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:9be4fdb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be4fdb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be52b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:9be55442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be55442-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9be581ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxy polyethylene glycol-epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:9be5a5d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:5167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenograstim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:9be5c99a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:5169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eldecalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:9be5edc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:5169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eldecalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9be61616-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin zeta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:9be639de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05362 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast targets Unclassified (Intercellular adhesion molecule 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:9be665e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:9be665e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:9be6a18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:9be6a18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:9be6a18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:9be6ddee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:9be6ddee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:9be71246-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etelcalcetide is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:9be73aaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eteplirsen is binding agent of RNA (exon 51 of dystrophin pre-mRNA) DrugCentral uuid:9be75f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaratumab is antibody binding of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:9be787bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallium (68Ga) edotreotide is antagonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9be7b0f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18177 biolink:molecularly_interacts_with DrugCentral:5186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezlotoxumab is antibody binding of Enzyme (Toxin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:9be7d91a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 radotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.514']} DrugCentral uuid:9be80124-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9be82938-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9be85d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9be85d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9be85d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9be85d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9be8a6b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9be8ced8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9be8f82c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9be92054-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.87']} DrugCentral uuid:9be94872-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.276']} DrugCentral uuid:9be97068-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:9be998fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:9be9c0fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9be9e8fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:9bea1112-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9bea39bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9bea61d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9bea89e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9beab1e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:9beadac0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9beb03c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:9beb2bec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9beb5400-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9beb7c6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19438 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide targets Unclassified (Tumor necrosis factor receptor superfamily member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:9beba482-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.721']} DrugCentral uuid:9bebccaa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:9bebf554-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9bec1ea8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmutinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.036']} DrugCentral uuid:9bec46c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9bec6eda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.368']} DrugCentral uuid:9bec9810-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.276']} DrugCentral uuid:9becc02e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:9bece856-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9bed1146-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17752 biolink:molecularly_interacts_with DrugCentral:5214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telotristat ethyl is inhibitor of Enzyme (Tryptophan 5-hydroxylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:9bed39aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclabuvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:9bed61c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O39930 biolink:molecularly_interacts_with DrugCentral:5215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclabuvir targets Unclassified (RNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9bed89d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9bedb1fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9beddaae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:9bee0330-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:9bee2b62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:9bee5380-dc5e-11ec-be2c-0242ac110005 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:9bee7f0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:9beeaa6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:9beed594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9beefd9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naldemedine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:9bef2620-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naldemedine is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:9bef4e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5221 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avelumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:9bef7224-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9bef9a9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9befc2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9befeaec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9bf01328-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9bf03c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9bf067a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:9bf091c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9bf0b9f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9bf0e26c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:9bf10a80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:5223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ocrelizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:9bf1333e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24394 biolink:molecularly_interacts_with DrugCentral:5224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dupilumab is antibody binding of Membrane receptor (Interleukin-4 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.06']} DrugCentral uuid:9bf15b52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deutetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:9bf17fba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:5227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:9bf1a7d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:9bf1d014-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:9bf1f95e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55859 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.64']} DrugCentral uuid:9bf22280-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine is inhibitor of Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.143']} DrugCentral uuid:9bf24a9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9bf272bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9bf29ada-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9bf2c42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9bf2ec56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:9bf31456-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9bf33c6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9bf3651e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9bf38d1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9bf3b532-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9bf3dd46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9bf408d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9bf430de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9bf45910-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9bf48160-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9bf4a96a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:9bf4d17e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9bf4f97e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9bf5221e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9bf54a14-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9bf57228-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9bf59a3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9bf5c3b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9bf5ebcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9bf613fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9bf63c08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9bf664e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9bf68cee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9bf6b624-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9bf6de38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9bf70782-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9bf72f96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9bf75836-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9bf7804a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9bf7aaa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9bf7d2b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9bf7fc28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:9bf8243c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9bf84d22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9bf8754a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9bf89d68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9bf8c69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9bf8eed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9bf916da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9bf93ee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9bf96838-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9bf99164-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9bf9b950-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9bf9e16e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9bfa0a40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9bfa327c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9bfa5a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9bfa839e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9bfaac52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9bfad484-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9bfafca2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:9bfb24d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9bfb4fae-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9bfb7b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9bfba33c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9bfbcb6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:9bfbf404-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9bfc1c22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9bfc444a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9bfc6cc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9bfc94ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9bfcbcf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9bfce508-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9bfd0e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9bfd367a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9bfd5e8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9bfd86a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9bfdaf42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9bfdd882-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9bfe0122-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9bfe292c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9bfe51ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9bfe7abc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9bfea2c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9bfecada-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9bfef55a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9bff1f62-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9bff4776-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9bff6f80-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9bff9848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9bffc05c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9bffe870-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:9c00107a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9c003906-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9c00611a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9c008938-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9c00b1ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9c00dc3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9c010462-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9c012c62-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9c015516-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9c017d52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9c01a566-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9c01cd66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c01f66a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9c021e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:9c02476e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9c027054-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9c029a02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9c02c234-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:9c02ea52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9c031266-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c033ae8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c036306-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9c038b10-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9c03b32e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9c03dd22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9c04054a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9c042d5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9c04557c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9c048114-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c04aba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9c04d3d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9c04fcb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9c0524d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9c054d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9c057510-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9c059d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9c05c588-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9c05edc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9c0616be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9c063ff4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9c066812-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9c06903a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:9c06b862-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9c06e198-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9c0709ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9c0731d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9c0759f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9c078274-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c07aa92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c07d2a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9c07fab0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9c082454-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:9c084c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:9c087490-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9c089ca4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c08c602-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9c08ee02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9c091616-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c093e84-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9c0966a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9c098e98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9c09b7e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9c09e172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9c0a0ab2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9c0a32d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9c0a5aee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9c0a8406-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9c0aac24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9c0ad42e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9c0afc4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c0b2514-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9c0b4d1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9c0b7528-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9c0b9d3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c0bc690-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9c0beeb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9c0c16cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:9c0c3ed6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9c0c6794-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9c0c8fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9c0cb7d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9c0cdff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9c0d0870-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9c0d3098-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:9c0d58b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9c0d80d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c0dab5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c0dd35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9c0dfc44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9c0e250c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9c0e4d16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c0e753e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c0e9d48-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9c0ec5ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9c0eedde-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9c0f1606-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9c0f3e10-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9c0f67e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9c0f9022-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9c0fb976-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9c0fe18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9c100a52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9c10325c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9c105a8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9c1082a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c10ab24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9c10d32e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c10fb38-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9c112356-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9c114d68-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9c11757c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9c119d90-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:9c11c676-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9c11ef34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c1217d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:9c123ffc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9c12687e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9c12909c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9c12b8b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51817 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit PRKX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9c12e0ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9c1309e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9c13322c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:5232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abaloparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9c135a40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:9c138268-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:9c13aafe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.137']} DrugCentral uuid:9c13d308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:9c13fb12-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:9c142344-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:9c144bb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 durvalumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:9c146f84-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5235 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenegermin is agonist of Kinase (High affinity nerve growth factor receptor) DrugCentral uuid:9c149356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08138 biolink:molecularly_interacts_with DrugCentral:5235 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenegermin is agonist of Membrane receptor (Tumor necrosis factor receptor superfamily member 16) DrugCentral uuid:9c14bb1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:9c14bb1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:9c14f008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evogliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:9c15181c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:9c154030-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c156970-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c15930a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.081']} DrugCentral uuid:9c15bb46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:9c15e364-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9c160bb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:9c163454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:9c165c90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.42']} DrugCentral uuid:9c1684c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:9c16ae0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pibrentasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.19']} DrugCentral uuid:9c16d800-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:5244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pibrentasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9c17001e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:5245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corifollitropin alfa is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:9c172846-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:9c172846-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:9c17567c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inotuzumab ozogamicin is antibody binding of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9c177ea4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:9c17a6ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.801']} DrugCentral uuid:9c17cecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9c17f730-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:9c181f26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:9c184744-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:9c186f76-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9c18985c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9c18c084-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48735 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP], mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9c18e88e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c1910ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:9c1939e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9c1962e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9c198af0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c19b2fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9c19db86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9c1a03a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c1a2bb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c1a5444-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9c1a7c80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9c1aa494-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9c1acca8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9c1af598-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9c1b1db6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9c1b46e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9c1b6f0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9c1b9804-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9c1bc036-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9c1be836-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9c1c1054-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9c1c393a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9c1c616c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c1c8976-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9c1cb18a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9c1cd9ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9c1d0216-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9c1d2aa2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9c1d53ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9c1d7c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9c1da4d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:9c1dcce6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9c1df4fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9c1e1dae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:9c1e45d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c1e6df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9c1e961c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9c1ebe9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:9c1ee6c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9c1f0ed0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9c1f3798-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:9c1f5fb6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9c1f87d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9c1fafde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9c1fd932-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9c2001e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9c202a0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9c205218-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9c207a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9c20a286-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9c20cab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9c20f2c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9c211cde-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9c2145e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9c216e14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9c21961e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:9c21bf9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c21e7cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:9c221008-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9c22381c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9c22609e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9c2288bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9c22b0d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9c22d8e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:9c2301a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9c2329ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9c2351ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9c2379ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9c23a4cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9c23cce0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9c23f576-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9c241df8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9c24460c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:9c246e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9c24962a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9c24bed4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9c24e6f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c250f10-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9c253828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9c256230-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:9c258a76-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9c25b28a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9c25daa8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c260384-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9c262cd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9c26550a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c267d1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:9c26a654-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9c26ce72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9c26f690-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:9c271fd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9c27492e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9c27714c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:9c279956-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9c27c19c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c27ea50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9c28126e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9c283a82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9c28639a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9c288bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY57 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 32B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9c28b3e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:9c28dc08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.036']} DrugCentral uuid:9c29052a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:9c292e38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:9c29566a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.432']} DrugCentral uuid:9c297e7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:9c29a7d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:9c29cff0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:9c29f872-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:5257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butylphthalide is blocker of Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:9c2a2072-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:9c2a494e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:9c2a716c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.764']} DrugCentral uuid:9c2a998a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.788']} DrugCentral uuid:9c2ac1b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.375']} DrugCentral uuid:9c2aeafc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.866']} DrugCentral uuid:9c2b1310-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:9c2b3b42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:9c2b636a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.796']} DrugCentral uuid:9c2b8caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:9c2bb4b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:9c2bdcc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9c2c04d2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9c2c2dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9c2c55ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9c2c7dc2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9c2ca75c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:9c2ccff2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:9c2cf914-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:9c2d2240-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9c2d4ab8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:9c2d72d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:9c2d9af4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:9c2dc308-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:9c2deb80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.434']} DrugCentral uuid:9c2e139e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.292']} DrugCentral uuid:9c2e3ba8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:5261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprostene bunod targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9c2e63c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:5261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprostene bunod is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9c2e94d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:9c2e94d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:9c2e94d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:9c2ed324-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01344 biolink:molecularly_interacts_with DrugCentral:5263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benralizumab is antibody binding of Membrane receptor (Interleukin-5 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.959']} DrugCentral uuid:9c2efb42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:5267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 semaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.42']} DrugCentral uuid:9c2f243c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.73']} DrugCentral uuid:9c2f4c78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00740 biolink:molecularly_interacts_with DrugCentral:5268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor IX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c2f7496-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9c2f9cbe-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:9c2fc522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.94']} DrugCentral uuid:9c2fed40-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9c30155e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.708']} DrugCentral uuid:9c303d9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.057']} DrugCentral uuid:9c306860-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:5271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macimorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:9c309150-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II is agonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.2']} DrugCentral uuid:9c30b978-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:9c30e1be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:9c310e46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9c313682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II is agonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9c315e96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:9c3186fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:9c31af36-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.125']} DrugCentral uuid:9c31d75e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lutetium (177Lu) oxodotreotide is agonist of GPCR (Somatostatin receptor type 2) DrugCentral uuid:9c31fb76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tezacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9c3224ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12908 biolink:molecularly_interacts_with DrugCentral:5277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elobixibat is inhibitor of Transporter (Ileal sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.276']} DrugCentral uuid:9c324f4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apalutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9c32779a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apalutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:9c329fb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01730 biolink:molecularly_interacts_with DrugCentral:5279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibalizumab is antibody binding of Membrane receptor (T-cell surface glycoprotein CD4) DrugCentral uuid:9c32c51a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9c32ed24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:9c331560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9c333d88-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.092']} DrugCentral uuid:9c336682-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.387']} DrugCentral uuid:9c339292-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:9c339292-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:9c33c5e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZV9 biolink:molecularly_interacts_with DrugCentral:5282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 burosumab is antibody binding of Secreted (Fibroblast growth factor 23) DrugCentral uuid:9c33e9ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosnetupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:9c341974-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:9c341974-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:9c344df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avatrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:9c347612-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:5286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxidectin is inhibitor of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:9c349a52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9c34c27a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9c34eaac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is agonist of GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:9c3512ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:9c353b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9c3563c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:9c358bec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9c35b40a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5S1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:9c35dd68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:9c36059a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is inhibitor of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:9c36296c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is antagonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9c365194-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c367a16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:9c36a248-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.328']} DrugCentral uuid:9c36ca70-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9c36f2a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:9c371b7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33815 biolink:molecularly_interacts_with DrugCentral:5291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tecovirimat is inhibitor of Viral envelope protein (Envelope protein F13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.382']} DrugCentral uuid:9c3743b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5292 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivosidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.149']} DrugCentral uuid:9c376be2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9c37940a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8SPZ1 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9c37be4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:9c37e676-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9c380e9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9c3837ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:9c3861c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c3889f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9c38b2b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.638']} DrugCentral uuid:9c38db58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:9c3903a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:9c392bb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9c3953c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9c397d38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:9c39a88a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9c39d2d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.133']} DrugCentral uuid:9c39fb0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9c3a23f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:9c3a4c18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baloxavir marboxil is inhibitor of Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.854']} DrugCentral uuid:9c3a742c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9c3a9c5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.959']} DrugCentral uuid:9c3ac4e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:9c3aed12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9c3b154e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:9c3b3d6c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:9c3b679c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9c3b8fd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:9c3bb7f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:9c3be032-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:9c3c0a08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.569']} DrugCentral uuid:9c3c323a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:9c3c5a58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:9c3c8302-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9c3cab52-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:9c3cd398-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9c3cfc74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9c3d25fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:5304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glasdegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9c3d4e4a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glasdegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9c3d7690-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.187']} DrugCentral uuid:9c3d9eb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.092']} DrugCentral uuid:9c3dc76c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.975']} DrugCentral uuid:9c3defda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:9c3e1802-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:9c3e408e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9c3e6a32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9c3e9250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9c3eba64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c3ee2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9c3f0d2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:9c3f3548-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5307 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evocalcet is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:9c3f5d70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04275 biolink:molecularly_interacts_with DrugCentral:5308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caplacizumab is antibody binding of Unclassified (von Willebrand factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.509']} DrugCentral uuid:9c3f85a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanadelumab is antibody binding of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:9c3fae60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:9c3fd75a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O02662 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9c3fff8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q28524 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9c4027aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:9c4050b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omidenepag isopropyl is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:9c4078d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 patisiran is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:9c409cb2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxetumomab pasudotox is binding agent of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9c40c4ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5315 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fremanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:9c40eee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galcanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9c411732-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cemiplimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.102']} DrugCentral uuid:9c413f6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inotersen is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:9c416354-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:5320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emapalumab is antibody binding of Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:9c418c08-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:5322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ravulizumab is antibody binding of Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.357']} DrugCentral uuid:9c41b818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:9c41b818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:9c41e590-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:9c4215b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:9c4215b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:9c4215b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:9c425bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:9c425bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:9c425bb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:9c42a2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:9c42a2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:9c42a2dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:9c42e4fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.088']} DrugCentral uuid:9c430e16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:9c433652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.848']} DrugCentral uuid:9c435f2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:9c43886e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3']} DrugCentral uuid:9c43b08c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:9c43d904-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.409']} DrugCentral uuid:9c440118-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.009']} DrugCentral uuid:9c442918-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:9c445118-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:9c447a94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.434']} DrugCentral uuid:9c44a500-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:9c44cd14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.921']} DrugCentral uuid:9c44f53c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:9c451ecc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:9c4546d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9c456eea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c459708-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9c45bf8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Z1L0 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c45e7d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:9c460ff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:9c463848-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:9c46612e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.02']} DrugCentral uuid:9c468956-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:9c46ad50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:9c46d8ac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14980 biolink:molecularly_interacts_with DrugCentral:5330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selinexor is inhibitor of Nuclear other (Exportin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:9c4701a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prabotulinumtoxinA is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c474422-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c47b5c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40259 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is antibody binding of Tumour-associated antigen (B-cell antigen receptor complex-associated protein beta chain) DrugCentral uuid:9c47d9aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9c4801f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is antagonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:9c482734-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.187']} DrugCentral uuid:9c485268-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02656 biolink:molecularly_interacts_with DrugCentral:5335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 volanesorsen is antisense inhibitor of RNA (apolipoprotein C-III (apoC-III) mRNA) DrugCentral uuid:9c487806-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risankizumab is inhibitor of Cytokine (Interleukin-23 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:9c48a42a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9c48a42a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:9c48d292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:9c48fad8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.444']} DrugCentral uuid:9c492382-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9c494b8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9c4973fa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9c499c0e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9c49c422-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9c49ec40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:9c4a174c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:9c4a405a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:9c4a6878-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9c4a9154-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9c4ab968-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9c4ae19a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c4b09c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9c4b3230-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9c4b5a4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:9c4b8276-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9c4baa94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9c4bd41a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9c4bfc38-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9c4c246a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9c4c4c7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:9c4c7528-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:9c4c9d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9c4cc5be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9c4ceddc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9c4d1654-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9c4d3e54-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:9c4d6672-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9c4d8e86-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9c4db7c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9c4ddfda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9c4e07e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9c4e3200-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c4e5a82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9c4e82a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9c4eaadc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c4ed35e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9c4efba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.796']} DrugCentral uuid:9c4f23e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8RL90 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9c4f4bf4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2PUH3 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:9c4f7548-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9X5A7 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9c4f9de8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q93LQ9 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9c4fc610-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q93DC4 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:9c4fee38-dc5e-11ec-be2c-0242ac110005 UniProtKB:B1PL86 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9c501692-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c503ea6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9c5066b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:9c508ed8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:9c50b7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9c50e004-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.56']} DrugCentral uuid:9c510818-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:9c51304a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.88']} DrugCentral uuid:9c51598a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9c518194-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:9c51a994-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9c51d19e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:9c51fa02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9c52231a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9c524b38-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:9c52734c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:9c529c14-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:9c52c4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9c52ecd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9c53150e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9c53410a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9c536c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:9c5394b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c53bd2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:9c53e560-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9c540d56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9c5436be-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:9c545ffe-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:9c5488bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c54b0d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:9c54d8f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9c55024c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:9c552a74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9c555292-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:9c557a9c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9c55a314-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c55cb28-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:9c55f35a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9c561c54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:9c564526-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9c566d3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9c56954e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9c56bd58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c56e706-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9c570f10-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9c573742-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9c576014-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c578878-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c57b096-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9c57d8b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c580118-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:9c582940-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c585154-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:9c587986-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c58a226-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9c58ca58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:9c58f24e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9c591a76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9c594352-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c596b70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9c59937a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:9c59bb8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9c59e406-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c5a0e04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9c5a3636-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9c5a5e72-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9c5a8956-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:9c5ab408-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9c5adc26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:9c5b044e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:9c5b2d98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:9c5b55b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c5b7dd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9c5ba64c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9c5bce56-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c5bf674-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9c5c1e74-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:9c5c47be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c5c70e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9c5c98f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9c5cc0f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:9c5ce9b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:9c5d11d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9c5d39da-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:9c5d6202-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9c5d8a5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c5db2a2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9c5ddaac-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:9c5e03b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9c5e2e1c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:9c5e56da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9c5e7f02-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9c5ea716-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9c5ecfd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:9c5ef7f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c5f2006-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9c5f481a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9c5f709c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:9c5f98b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9c5fc0d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9c5fe98c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9c60154c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:9c603d6a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9c60657e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:9c608e3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9c60b650-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c60de78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9c61068c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:9c612ef0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9c615704-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9c617f22-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:9c61a736-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c61d166-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:9c61fd94-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:9c622760-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c624f74-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9c627832-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c62a050-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:9c62c878-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:9c62f08c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:9c631922-dc5e-11ec-be2c-0242ac110005 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9c634136-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9c636954-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9c6391fe-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9c63bcb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9c63e4ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c640cf6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:9c643582-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9c645da0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9c6485be-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9c64adc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c64d67c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c64fe9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:9c65269a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c654ec2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9c65779e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9c659fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:9c65c7e4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c65f1ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c661a50-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9c66428c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c666aa0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9c6692c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c66bb90-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c66e3ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9c670bcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c6733e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:9c675f32-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c6787c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9c67afdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:9c67d836-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:9c680054-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9c682868-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9c68507c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:9c68793a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9c68a14e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:9c68c9f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9c68f216-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9c691b92-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9c69466c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9c696e8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9c69969e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9c69bf20-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c69e842-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c6a1060-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9c6a387e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9c6a6132-dc5e-11ec-be2c-0242ac110005 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9c6a8946-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c6ab15a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9c6ad978-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c6b02a4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9c6b2aa4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:9c6b52d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9c6b7aea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9c6ba3d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9c6bcbee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9c6bf524-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9c6c1fcc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9c6c4858-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c6c7076-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c6c9894-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:9c6cc1fc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:9c6ceb46-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:9c6d1364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9c6d3b78-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9c6d645e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9c6d8c86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9c6db490-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:9c6ddda8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:9c6e0616-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9c6e2e34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9c6e5652-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9c6e7e66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9c6ea90e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c6ed424-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9c6eff4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c6f2ae6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:9c6f530e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:9c6f7bae-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9c6fa3cc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9c6fcc58-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9c6ff476-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:9c701c8a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:9c70448a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:9c706d98-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9c7095b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9c70bdca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:9c70e5f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c710eb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9c7136ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9c715ee2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9c718700-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:9c71af64-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9c71d958-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9c72018a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:9c7229bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c72537e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9c727b92-dc5e-11ec-be2c-0242ac110005 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9c72a3ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9c72cbec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:9c72f496-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:9c731caa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9c7344b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:9c736cc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c739540-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c73bd5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:9c73e572-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:9c740e4e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9c7436d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c745eee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9c748716-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:9c74afe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:9c74d810-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:9c75001a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:9c752838-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:9c75509c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:9c7578ba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9c75a0d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9c75c9f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:9c75f326-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:9c761bda-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c7643ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9c766c16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c76954c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9c76bd74-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c76e592-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9c770db0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9c77363c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9c775e6e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c778682-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9c77ae96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9c77db46-dc5e-11ec-be2c-0242ac110005 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:9c7804c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:9c782cd6-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:9c7855a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:9c787dd0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c78a5ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9c78ce02-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:9c78f684-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:9c791eac-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:9c7946ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c796ec0-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9c799864-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:9c79c370-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9c79eb98-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:9c7a13c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9c7a3c88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:9c7a64b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9c7a8cce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c7ab4ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:9c7add5a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9c7b0582-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9c7b2d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:9c7b55aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9c7b7fc6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9c7ba7da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9c7bcff8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:9c7bf816-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9c7c20de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:9c7c48f2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:9c7c7106-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:9c7c9974-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9c7cc214-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:9c7cea28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9c7d1246-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:9c7d3b9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9c7d65c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:9c7d8dde-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9c7db7dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c7de0b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c7e08d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9c7e30ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:9c7e5908-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:9c7e8216-dc5e-11ec-be2c-0242ac110005 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:9c7eaa52-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:9c7ed27a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:9c7efa8e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:9c7f241e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:9c7f4c46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51957 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:9c7f7478-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q58F21 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Unclassified (Bromodomain testis-specific protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9c7f9c96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96PY6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9c7fc57c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:9c7fedae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9c8015c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9c803df4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:9c8066ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c808f20-dc5e-11ec-be2c-0242ac110005 UniProtKB:P26433 biolink:molecularly_interacts_with DrugCentral:5349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenapanor targets Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:9c80b752-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48764 biolink:molecularly_interacts_with DrugCentral:5349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenapanor is inhibitor of Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:9c80e04c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9c810946-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:9c81315a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9c815964-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:5351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasmiditan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:9c8182ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9c81ab3a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c81d362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9c81fc7a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9c822556-dc5e-11ec-be2c-0242ac110005 UniProtKB:G1C775 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:9c824da6-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6T4V3 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:9c8275d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:H4I819 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c829e1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0A0W8ASI8 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:9c82c876-dc5e-11ec-be2c-0242ac110005 UniProtKB:A6T4M7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9c82f3f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:G3XD46 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:9c831e52-dc5e-11ec-be2c-0242ac110005 UniProtKB:D0CCM7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:9c834698-dc5e-11ec-be2c-0242ac110005 UniProtKB:A0A5E6DR09 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:9c836f24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanubrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:9c839760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13196 biolink:molecularly_interacts_with DrugCentral:5354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 givosiran is antisense inhibitor of RNA (aminolevulinate synthase1 (ALAS1) mRNA) DrugCentral uuid:9c83bc68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:9c83e49a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9c840d9e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:9c8435da-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:9c845e0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:9c84862a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:9c84b0f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:9c84d954-dc5e-11ec-be2c-0242ac110005 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Transporter (hemoglobin subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:9c850172-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 golodirsen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:9c852594-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:9c854dbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:9c857706-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:9c859f42-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:9c85c828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9c85f050-dc5e-11ec-be2c-0242ac110005 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:9c8618a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:9c8640c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:9c866b34-dc5e-11ec-be2c-0242ac110005 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:9c86947e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:9c86bcb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99572 biolink:molecularly_interacts_with DrugCentral:5359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brilliant Blue G is antagonist of Ion channel (P2X purinoceptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9c86e4ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P37840 biolink:molecularly_interacts_with DrugCentral:5359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brilliant Blue G targets Transporter (Alpha-synuclein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9c870d3c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9c87356e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9c875dd2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c878618-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubrogepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:9c87aeea-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9BQB4 biolink:molecularly_interacts_with DrugCentral:5362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romosozumab is binding agent of Glycoprotein (Sclerostin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.7']} DrugCentral uuid:9c87d730-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brolucizumab is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9c87ff76-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95390 biolink:molecularly_interacts_with DrugCentral:5364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.13']} DrugCentral uuid:9c8827a8-dc5e-11ec-be2c-0242ac110005 UniProtKB:O14793 biolink:molecularly_interacts_with DrugCentral:5364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.69']} DrugCentral uuid:9c885142-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16109 biolink:molecularly_interacts_with DrugCentral:5365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizanlizumab is inhibitor of Adhesion (P-selectin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c8897ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:9c890bc8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96NY8 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Nectin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:9c89342c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab deruxtecan is binding agent of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:9c895c7c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab deruxtecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:9c89854e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 botulinum toxin type A is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:9c89a948-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:9c89d170-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9c89f9c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9c8a22f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:9c8a4b0a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elexacaftor targets Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:9c8a767a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9c8a9ede-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine is inhibitor of Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) DrugCentral uuid:9c8ac328-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine is inhibitor of Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) DrugCentral uuid:9c8ae79a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:5376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remdesivir is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c8b0fb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9c8b37ea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:9c8b60bc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P05532 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:9c8b8902-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:9c8bb13e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:9c8bd970-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9c8c0544-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92800 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:9c8c2f60-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15910 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9c8c579c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimegepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.56']} DrugCentral uuid:9c8c8032-dc5e-11ec-be2c-0242ac110005 UniProtKB:P53396 biolink:molecularly_interacts_with DrugCentral:5382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bempedoic acid is inhibitor of Enzyme (ATP-citrate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:9c8ca95e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9c8cd190-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:9c8cf9c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:9c8d229e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:9c8d4ada-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9c8d72d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:9c8d9ac6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:9c8dc3ca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:9c8debe8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:9c8e1406-dc5e-11ec-be2c-0242ac110005 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9c8e3c2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:9c8e64c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isatuximab is binding agent of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9c8e8e18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.82']} DrugCentral uuid:9c8eb654-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10092 biolink:molecularly_interacts_with DrugCentral:5386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:9c8ede9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teprotumumab is antagonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9c8f074e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:9c8f3016-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9c8f5852-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:9c8f807a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:9c8fa9ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:9c8fd5b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:9c8fd5b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:9c9008ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:9c90316e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9c905a86-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:9c9082c2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:9c90aaea-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is antibody binding of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.71']} DrugCentral uuid:9c90d3d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is binding agent of Enzyme (DNA topoisomerase 1) DrugCentral uuid:9c90f7d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09758 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is antibody binding of Tumour-associated antigen (Tumor-associated calcium signal transducer 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.58']} DrugCentral uuid:9c91201a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capmatinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.88']} DrugCentral uuid:9c91484c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selpercatinib is inhibitor of Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:9c9172b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selpercatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:9c919b26-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9c91c362-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:9c91eb80-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:9c921416-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:9c923c66-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9c9264b6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:9c928d06-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoroestradiol F 18 is binding agent of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.07']} DrugCentral uuid:9c92b600-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:5396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flortaucipir F 18 is binding agent of Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:9c92de46-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inebilizumab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:9c930696-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inebilizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:9c933760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9c933760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9c933760-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:9c937dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c937dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c937dce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:9c93c4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9c93c4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9c93c4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:9c940c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:9c940c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:9c940c76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:9c9461d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9c9461d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9c9461d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9c9461d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9c9461d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9c9461d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9c9461d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:9c94ccc4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:5401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostemsavir is inhibitor of Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:9c94f50a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32320 biolink:molecularly_interacts_with DrugCentral:5402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inqovi is inhibitor of Enzyme (Cytidine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:9c951fbc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c9547ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9c95700c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:9c959820-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9c95c110-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51685 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9c95e942-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafasitamab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:9c961188-dc5e-11ec-be2c-0242ac110005 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:9c9639c4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12314 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (High affinity immunoglobulin gamma Fc receptor I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:9c966250-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9c968ba4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02223 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Tumour-associated antigen (Tumor necrosis factor receptor superfamily member 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:9c96b3e0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9c96dd16-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9c9707f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:9c973220-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:9c975a52-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:9c978306-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9c97ab1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine is agonist of GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:9c97d342-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9c97fb7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viltolarsen is binding agent of RNA (exon 53 of dystrophin pre-mRNA) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:9c98284c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9c98284c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9c985bb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clascoterone is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9c9883f0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copper dotatate Cu-64 is binding agent of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:9c98ae16-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:9c98d634-dc5e-11ec-be2c-0242ac110005 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9c98fe70-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9c992698-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:9c994ff6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9c99781e-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9c99a050-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:9c99c86e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:9c99f0e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:9c9a192c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:9c9a423a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somapacitan targets GPCR (Growth hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:9c9a6a76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9c9a947e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9c9abca6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01111 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase NRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:9c9ae4ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9c9b0cd8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:9c9b3992-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9c9b3992-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:9c9b6cb4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UJM8 biolink:molecularly_interacts_with DrugCentral:5415 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumasiran is antisense inhibitor of RNA (Hydroxyacid oxidase 1 (HAO1) mRNA) DrugCentral uuid:9c9b90ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9c9bb926-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9c9be16c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:9c9c099e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:9c9c31d0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:9c9c5b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:9c9c869e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:9c9cb11e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:5417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bulevirtide is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:9c9ce4b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:9c9ce4b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:9c9ce4b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:9c9ce4b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:9c9d272a-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9c9d4f2a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9c9d7748-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:9c9d9fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9c9dc7de-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:9c9df0ec-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:9c9e1a18-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:9c9e44c0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:9c9e6d4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:9c9e956a-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:9c9ebdba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:9c9ee68c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:9c9f0f04-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9c9f372c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9c9f5fb8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:9c9f8858-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8N543 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Prolyl 3-hydroxylase OGFOD1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9c9fb094-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:9c9fd8b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:9ca001de-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.93']} DrugCentral uuid:9ca02d12-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:9ca05800-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:9ca08046-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:9ca0a92c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:9ca0d15e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:5422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 borofalan (10B) is substrate of Transporter (L-type amino acid transporter 1) DrugCentral uuid:9ca0f5b2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9ca11f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9ca147a6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9ca17050-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:9ca19878-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:9ca1c082-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:9ca1ea94-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:9ca212c6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:9ca23af8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9ca26320-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:9ca28bfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tepotinib is inhibitor of Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:9ca2b41a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tepotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:9ca2dc56-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9ca3047e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:9ca32d28-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:9ca3553c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:9ca37d96-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:9ca3a5b4-dc5e-11ec-be2c-0242ac110005 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:9ca3cf76-dc5e-11ec-be2c-0242ac110005 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:9ca3f906-dc5e-11ec-be2c-0242ac110005 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:9ca4214c-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:9ca44a14-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:9ca47250-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9ca49a82-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:9ca4c2e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:9ca4eb72-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofpironium bromide is inhibitor of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:9ca51052-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07288 biolink:molecularly_interacts_with DrugCentral:5429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallium (68Ga) gozetotide is binding agent of Surface antigen (Prostate-specific antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:9ca53898-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5430 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 berotralstat is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:9ca560d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:9ca58a64-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9ca5b354-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:9ca5dc58-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:9ca6048a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:9ca62d3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:9ca6558e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:9ca67dca-dc5e-11ec-be2c-0242ac110005 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ansuvimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:9ca6a624-dc5e-11ec-be2c-0242ac110005 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 margetuximab is antagonist of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.55']} DrugCentral uuid:9ca6cec4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 margetuximab is antagonist of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:9ca6f746-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atoltivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:9ca71f96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atoltivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:9ca747e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maftivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:9ca772d4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 odesivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:9ca79b24-dc5e-11ec-be2c-0242ac110005 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 odesivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:9ca7c356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P20595 biolink:molecularly_interacts_with DrugCentral:5439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:9ca7eb88-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:5439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) DrugCentral uuid:9ca81004-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9ca83822-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9ca86054-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:9ca88886-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:9ca8b108-dc5e-11ec-be2c-0242ac110005 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:9ca8d94e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:9ca90216-dc5e-11ec-be2c-0242ac110005 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:9ca92b60-dc5e-11ec-be2c-0242ac110005 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9ca9555e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9ca97d9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:9ca9a69e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9ca9d074-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:9ca9f89c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:9caa20ce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:9caa48f6-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:9caa71a0-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6ZWH5 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Serine/threonine-protein kinase Nek10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.57']} DrugCentral uuid:9caa99dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:9caac22c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:9caaea5e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casimersen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:9cab0fca-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9NZB8 biolink:molecularly_interacts_with DrugCentral:5444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosdenopterin targets Enzyme (Molybdenum cofactor biosynthesis protein 1) DrugCentral uuid:9cab339c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:9cab5bce-dc5e-11ec-be2c-0242ac110005 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9cab83d8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:9cabac96-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:9cabd4aa-dc5e-11ec-be2c-0242ac110005 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:5447 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasiglucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:9cabfcdc-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9Y5C1 biolink:molecularly_interacts_with DrugCentral:5449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evinacumab is inhibitor of Secreted (Angiopoietin-related protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:9cac2522-dc5e-11ec-be2c-0242ac110005 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:9cac4db8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:5450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:9cac7608-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dostarlimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:9cac9e44-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loncastuximab tesirine is antibody binding of Surface antigen (B-lymphocyte antigen CD19) DrugCentral uuid:9cacc23e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5453 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bamlanivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:9cacec1e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etesevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:9cad1450-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casirivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.34']} DrugCentral uuid:9cad3c8c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imdevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.33']} DrugCentral uuid:9cad64e6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01024 biolink:molecularly_interacts_with DrugCentral:5457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegcetacoplan is inhibitor of Unclassified (Complement C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:9cad8f34-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04609 biolink:molecularly_interacts_with DrugCentral:5458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piflufolastat F-18 is binding agent of Enzyme (Glutamate carboxypeptidase 2) DrugCentral uuid:9cadb324-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9caddb2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9cae0356-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9cae2bce-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:9cae53e2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9cae7c00-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9caea432-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9caecee4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9caef72a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9caf1f5c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9caf484c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9caf7074-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9caf99c8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9cafc1dc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9cafea54-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9cb01268-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9cb03a9a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9cb062b8-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:9cb08c0c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9cb0b42a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9cb0dc3e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9cb1043e-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9cb12cfc-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9cb15510-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9cb17e32-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9cb1a66e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9cb1cefa-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:9cb1f72c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9cb21f40-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:9cb24754-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:9cb27206-dc5e-11ec-be2c-0242ac110005 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9cb29a2e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:9cb2c238-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9cb2eaba-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:9cb31364-dc5e-11ec-be2c-0242ac110005 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:9cb33b78-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:9cb36396-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:9cb38c22-dc5e-11ec-be2c-0242ac110005 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9cb3b454-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9cb3dc68-dc5e-11ec-be2c-0242ac110005 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9cb4047c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:9cb42db2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:9cb455da-dc5e-11ec-be2c-0242ac110005 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:9cb47dda-dc5e-11ec-be2c-0242ac110005 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:9cb4a5f8-dc5e-11ec-be2c-0242ac110005 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:9cb4cef2-dc5e-11ec-be2c-0242ac110005 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:9cb4f710-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:9cb51f1a-dc5e-11ec-be2c-0242ac110005 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:9cb54828-dc5e-11ec-be2c-0242ac110005 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:9cb571ae-dc5e-11ec-be2c-0242ac110005 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:9cb599d6-dc5e-11ec-be2c-0242ac110005 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:9cb5c1f4-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:9cb5ea26-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:9cb61424-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:9cb63c4c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:9cb66488-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:9cb68cb0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) DrugCentral uuid:9cb6b12c-dc5e-11ec-be2c-0242ac110005 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:9cb6d508-dc5e-11ec-be2c-0242ac110005 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) DrugCentral uuid:9cb6f8ee-dc5e-11ec-be2c-0242ac110005 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) DrugCentral uuid:9cb71cd4-dc5e-11ec-be2c-0242ac110005 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:9cb74556-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:9cb76d7e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is partial agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:9cb795b0-dc5e-11ec-be2c-0242ac110005 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotorasib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:9cb7bdec-dc5e-11ec-be2c-0242ac110005 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:9cb7e86c-dc5e-11ec-be2c-0242ac110005 UniProtKB:Q6FTN8 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:9cb8109e-dc5e-11ec-be2c-0242ac110005 UniProtKB:P87204 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral